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Two Honeysuckles: A Tale Of Dr. Jekyll And Mr. Hyde, W. John Hayden

Biology Faculty Publications

There are about 180 species of Lonicera (honeysuckles) widely distributed in the north temperate zone. These are mostly shrubby plants, but in Virginia, we have two species that are woody vines (lianas). These two lianous honeysuckles should be familiar to all Virginia Native Plant Society members. One is this year’s VNPS Wildflower of the Year, Lonicera sempervirens (coral honeysuckle), and the other is Lonicera japonica (Japanese honeysuckle), widely and deservedly reviled as one of our most aggressive invasive exotic species. Together, these two plants make an odd pair, a sort of botanical Dr. Jekyll and Mr. Hyde. What is it, …

Making Patents Useful, Sean B. Seymore

Vanderbilt Law School Faculty Publications

It is axiomatic in patent law that an invention must be useful. The utility requirement has been a part of the statutory scheme since the Patent Act of 1790. But what does it mean to be useful? The abstract and imprecise nature of the term combined with the lack of objective criteria for assessing it make utility the most malleable patentability requirement. As the invention landscape has evolved over time, the Patent Office and the courts have exploited this malleability to create technologically specific utility standards — de minimis for some inventions, but considerably more stringent for others. This has …

Differential Resource Allocation Of Black Mustard Plants (Brassica Nigra L.) With Proximity To Black Walnut Trees (Jug/Ans Californica L.) In A Southern California Riparian Ecosystem, Victor D. Carmona-Galindo, Matt Cronrod, Kellyanne Gold

Biology Faculty Works

The invasive forb Brassica nigra (black mustard) and the native tree Jug/ans californica (black walnut) are allelopathic species that suppress the growth of neighboring plants. This study evaluates how allocation to root, reproductive, and photosynthetic biomass in B. nigra was affected with proximity to J. califomica. We hypothesized that a joint suppressive effect would lead to lower root biomass allocation in B. nigra near J. californica due to reduced interspecific competition. Our results indicate that B. nigra plants growing near J. califomica had significantly lower root : total biomass ratios, and provide insights into how to effectively control this invasive …

Melt Water Input From The Bering Glacier Watershed Into The Gulf Of Alaska, Edward G. Josberger, Robert Shuchman, Liza K. Jenkins, K. A. Endsley

Michigan Tech Research Institute Publications

The annual runoff from the melting of large glaciers and snow fields along the northern perimeter of the Gulf of Alaska is a critical component of marine physical and biological systems; yet, most of this freshwater is not measured. Here we show estimates of melt for the watershed that contains the largest and longest glacier in North America, the Bering Glacier. The procedure combines in situ observations of snow and ice melt acquired by a long-term monitoring program, multispectral satellite observations, and nearby temperature measurements. The estimated melt is 40 km3 per melt season, ± 3.0 km3, observed over the …

A Lensing Effect Of Inner Retinal Cysts On Images Of The Photoreceptor Mosaic, Christopher S. Langlo, John A. Flatter, Alfredo Dubra, William J. Wirostko, Joseph Carroll

Biomedical Engineering Faculty Research and Publications

No abstract provided.

Evaluation Of Electrocoagulation For The Removal Of Chromium (Vi) From Brackish Groundwater, Shaima S Hamdan

Theses

Electrocoagulation (EC) has been evaluated for the removal of Cr (VI) from brackish groundwater using three different bench-scale EC reactors, namely batch stirred tank reactor (BSTR), continuous stirred tank reactor (CSTR) and a continuous electrocoagulation column (ECC). Batch EC process was experimentally examined at room temperature and the results indicated that Fe-Fe electrode pair was the most efficient arrangement and was able to achieve 100 % Cr removal at an electrocoagulation time of 5 minutes, a current density of 7.94 mA/cm², and pH of 8. A kinetic study of batch EC was then performed using both pseudo-first-order and …

Emotional Intelligence Predicts Success In Medical School, Nele Libbrecht, Filip Lievens, Bernd Carette, Stephane Cote

Research Collection Lee Kong Chian School Of Business

Accumulating evidence suggests that effective communication and interpersonal sensitivity during interactions between doctors and patients impact therapeutic outcomes. There is an important need to identify predictors of these behaviors, because traditional tests used in medical admissions offer limited predictions of "bedside manners" in medical practice. This study examined whether emotional intelligence would predict the performance of 367 medical students in medical school courses on communication and interpersonal sensitivity. One of the dimensions of emotional intelligence, the ability to regulate emotions, predicted performance in courses on communication and interpersonal sensitivity over the next 3 years of medical school, over and above …

Practicing Environmental Etiquette In Utah's Deserts, Jordan Burningham, Roslynn Brain

Environment and Society Faculty Publications

No abstract provided.

Identification Of T-Cell Epitopes In The Hepatitis C Virus Genotype 4 Proteome: A Step Towards Epitope-Driven Vaccine Development, Karim Mohamed Ali Abdel-Hady

Theses and Dissertations

Hepatitis C is an inflammatory infectious disease of the liver caused by the Hepatitis C Virus (HCV). It is a global pandemic, chronically inflicting 150 million people worldwide, with millions of new infections arising annually. The standard therapy of HCV is expensive, associated with severe side effects, and has variable success rates. Thus far, no HCV vaccine has been developed, owing to the challenges that faced and still face its development. Despite these challenges, several attempts have been taken to develop a vaccine, some of which have progressed to phase II clinical trials. Most of these attempts, however, have focused …

How Much Value Is Added By Value Added Models? An Analysis Of Teachers’ Performance Over Time Using New York State Assessment Data, Mariana Ristea

Dissertations, Theses, and Capstone Projects

There is a strong movement to evaluate teachers on the basis of students’ performance. To compare teachers fairly, as each may have a mixture of students with different abilities in a given subject area, one should account for variables reflective of students’ subject knowledge and background when entering a course. Most methods of control consist of highly sophisticated statistical models mostly difficult to explain to educators who are being evaluated using such methods. This research presents two value-added methods that could be replicated by using in-house resources and standardized student assessment data which are either continuous or ordinal. One method …

Reading The Restaurant: Social Class, Identity, And The Culture Of Consumption In The Nineteenth Century French Novel, Joseph J.B. Rienti

Dissertations, Theses, and Capstone Projects

The restaurant, like so many of the institutions of French modern society, developed at a very particular moment in history. In this project, I tell the story of the maturation of the restaurant and study its unique role in the social history of Paris during the nineteenth century. By examining the restaurant as a site of modernity, I illuminate its important role in precipitating class distinctions, locating the emerging consumer culture, highlighting gender differentiation, challenging prevailing views of domesticity, and revealing a debate over public and private space.

Through a close reading of the realist novel as a discourse on …

Identification And Characterization Of Protein Phopshatases Regulating The Sma/Mab Pathway In C. Elegans, Sheng Xiong

Dissertations, Theses, and Capstone Projects

TGF-beta signaling is a conserved signaling pathway among eukaryotes, which controls various normal cellular responses from cell proliferation to cell death. The mutations in its components are found in developmental disorders and cancer. Therefore, this signaling pathway is extensively investigated so that new therapeutic targets could be discovered and novel drugs could be developed. Previous studies suggested the involvement of phosphatases in regulation of TGF-beta signaling, but these studies were performed in cell culture rather than intact organisms. C. elegans is a tractable organism in which to study signaling in vivo. In C. elegans, growth is controled by a conserved …

Nickel-Catalyzed Cross-Coupling Reactions Involving Secondary And Tertiary Alkyl Nucleophiles, Amruta Ajit Joshi

Dissertations, Theses, and Capstone Projects

In the first chapter, introduction of transition metal-catalyzed cross-coupling reactions has been given. These transition metal-catalyzed C-C bond forming reactions have been used extensively in organic synthesis. Among them, C(sp2)-C(sp2) bond forming reactions have been widely studied over decades. More recently, some reports have demonstrated the use of C(sp3) nucleophiles and electrophiles in cross-coupling reactions. However, use of secondary and tertiary alkyl nucleophiles has remained a challenge due to competitive β-hydride elimination and slow transmetallation of bulky secondary and tertiary alkyl organometallic nucleophiles.

In the second chapter, the first general nickel-catalyzed Negishi reaction for the cross-coupling of unactivated, acyclic secondary …

Testing Assumptions Of Coevolution In An Egg-Rejecting Brood Parasite Host: Uncovering Sensory, Cognitive, And Evolutionary Drivers Of Responses To Parasitism In American Robins (Turdus Migratorius), Rebecca Croston

Dissertations, Theses, and Capstone Projects

Hosts of brood parasitic birds face fitness costs associated with rearing unrelated offspring. In response, the recognition and rejection of parasitic eggs is a common host defense. Brown-headed cowbirds (Molothrus ater) challenge coevolutionary theory, because although they exploit over 200 host species, they lay non-mimetic eggs, and most hosts do not combat cowbird parasitism with egg rejection. American robins (Turdus migratorius) are one of a handful of cowbird hosts known to recognize and remove cowbird eggs from the nest. I addressed the mechanistic and evolutionary drivers of egg rejection in this host species, by disentangling the roles of spectral tuning …

Battles With Words: Literate And Linguistic Resistance In Multi-Ethnic U.S. Literature And Everyday Life, Melissa A. Dennihy

Dissertations, Theses, and Capstone Projects

Battles with Words analyzes the role of multi-ethnic U.S. literature as an alternative form of cultural production which critiques and challenges U.S. linguistic and literate hegemony and homogeneity. The texts comprising this field continually emphasize the ways in which words, through language and literacy, become tools of power and action used by the ethnically marginalized to negotiate everyday advantages for themselves and challenge the linguistic and cultural domination of Anglo America. Through their critiques of the culture of English-only monolingualism that has continued to dominate the national landscape of the U.S. throughout the twentieth and twenty-first centuries, these authors indicate …

Discovering Regularity In Point Clouds Of Urban Scenes, Sam Friedman

Dissertations, Theses, and Capstone Projects

Despite the apparent chaos of the urban environment, cities are actually replete with regularity. From the grid of streets laid out over the earth, to the lattice of windows thrown up into the sky, periodic regularity abounds in the urban scene. Just as salient, though less uniform, are the self-similar branching patterns of trees and vegetation that line streets and fill parks. We propose novel methods for discovering these regularities in 3D range scans acquired by a time-of-flight laser sensor. The applications of this regularity information are broad, and we present two original algorithms. The first exploits the efficiency of …

The Interplay Of Visual Attention And Saccade Planning In Active Vision, Afsheen Khan

Dissertations, Theses, and Capstone Projects

Vision is a highly active process. When we view the world, we do not hold our eyes still, but constantly move them around in order to view the object or area of interest with the fovea (the region of the retina with the highest acuity). Saccades are the step-like movements that we most often employ for this purpose. In addition, our attention is constantly being covertly attracted or directed to points of interest. Combining these different aspects of viewing: visual processing, the orienting of attention, and eye movements can be referred to as `active vision'.

Most work on active vision …

Iron Regulates Mrna Translation Initiation Through Rna Iron Responsive Element (Ire), Jia Ma

Dissertations, Theses, and Capstone Projects

The non-coding IRE-RNA structure, a 30 nt stem loop structure, regulates synthesis of proteins in iron trafficking, cell cycling, and nervous system function. IRE-RNA binding with iron regulatory protein (IRP) proteins inhibits ribosome accessing mRNA. Increasing iron concentration decreases IRP binding with IRE-RNA. Previous models of IRE-mRNA translation regulation concentrate on Fe-S binding to IRP and IRP degradation after release from IRE-RNA. These models lack information on the details of decreasing IRE-RNA/IRP protein binding with iron concentration elevation. This research shows 1. Eukaryotic initiation factor 4F (eIF4F) binds to IRE-RNA with high affinity and works as a positive control element …

Nature's Goodness: An Aristotelian Account, Nathan K. Metzger

Dissertations, Theses, and Capstone Projects

Neo-Aristotelians have made major headway in moral theory, and it is now commonplace to find philosophers defending the reality of goodness through a teleological analysis of human being. Whatever the merits of this approach, it has suffered from a lack of a sustained defense of its pre-modern metaphysical panorama: the Aristotelian conception of the human good gets traction only if its decidedly pre-modern and `robust' philosophy of nature is defensible in its own right. In this dissertation, I aim to give a partial breakdown of the particular sort of metaphysical project that the Aristotelian moral theorist assumes, but does not …

"When I Heard About The March": Testimonies And Participatory Archiving In Peacebuilding, Carolina Muñoz Proto

Dissertations, Theses, and Capstone Projects

This dissertation studies the Memoscopio archive and its collection of testimonies about the 2009 World March for Peace and Nonviolence (the March). This collection came into existence during 2009 and 2010 through a participatory archiving project carried out by a team of peace advocates and researchers in collaboration with March participants. The March was a transnational and decentralized campaign that promoted peace, nonviolence, and justice through activities in 600 cities, social media, and a three-month march around the world. Through the case of Memoscopio and the March, this dissertation explores the personal and cultural meanings of transnational peace marchers in …

Long-Term Warming And The Size And Phenology Of Long Island Sound Plankton, Edward Rice

Dissertations, Theses, and Capstone Projects

In coastal ecosystems with decades of eutrophication and other anthropogenic stressors, the impact of climate change on planktonic communities can be difficult to detect. A time-series of monthly surface water temperatures in the Central Basin of Long Island Sound (LIS) from the late 1940s until 2012 indicates a warming rate of 0.03°C per year, with recent summer temperatures increasing most consistently. During this warming trend, the proportion of chlorophyll produced by smaller phytoplankton and flagellates appears to be higher during warmer summer and fall months, enabling an increase in annual chlorophyll despite static nutrient levels. The phenology of phytoplankton and …

Lipid Dependence In Ras-Driven Tumors, Darin Salloum

Dissertations, Theses, and Capstone Projects

Over past decade, metabolic alterations in cancer cells have received a substantial amount of interest. It had been established that cancer cells undergo a significant amount of metabolic alterations, and some of these alterations are similar to those in normal highly proliferative cells. However, it is becoming more apparent that many of the metabolic alterations are specific to particular oncogenic signaling pathways. Although altered metabolic machinery makes cancer cells more efficient at promoting growth when nutrients are supplied at the sufficient amounts, the dependency of cancer cells on particular metabolic reprogramming deems cancer cells susceptible to disruptions within metabolic network. …

Neuroimmune Crosstalk: A Role For Neuropeptide Y In Inflammatory Bowel Disease, Henry H. Ruiz

Dissertations, Theses, and Capstone Projects

Neuropeptide Y (NPY) is a 36-amino acid peptide widely expressed in the central and peripheral nervous systems. In addition to other cells, NPY is also synthesized and co-released from sympathetic nerve fibers functioning as a potent sympathetic neuromodulator. NPY has been implicated in playing important roles in the regulation of energy balance, appetite, anxiety, vascular tone, and immune cell functioning. In addition, immune cells of both the innate and adaptive immune systems express functional NPY receptors. Some immune cells can produce and secrete NPY, and genetic alteration of these receptors results in altered immune cell functioning. Its direct association with …

Intelligent Nano/Microgels For Cell Scaffold And Drug Delivery System, Jing Shen

Dissertations, Theses, and Capstone Projects

Stimulus-responsive polymer microgels swell and shrink reversibly upon exposure to various environmental stimuli such as change in pH, temperature, ionic strength or magnetic fields. Therefore, they become ideal candidates for biomaterial applications. For this work, we focus on the several intelligent microgels and their application on two areas: the cell scaffold and the drug delivery system.

As for the cell scaffold, it can be realized by colloidal supra-structure microgels, which constructed by the thermo-driven gelation of the colloidal dispersion of poly(N-isopropylacrylamide-co-acrylamide) poly(NIPAM-co-AAm) microgels (Chapter 3). Such microgels exhibit a reversible and continuous volume transition in water with volume phase transition …

Affective Language And Attitudes Toward Public Policy, Rachel A. Wolitzky

Dissertations, Theses, and Capstone Projects

This dissertation project focused on affective and unconscious processes involved in the evaluation of public policy. It follows recent scholarship in political psychology showing how the response to political messages depends greatly on what values and emotions are evoked. Of particular focus has been the notable discrepancy between the conscious way people construe their political judgments and the unconscious operations that more truly account for their views and actions. Motivated by a neuroscientific and psychoanalytic model of the mind and brain that recognizes both the pre-eminence of unconscious (implicit) processing and the primacy of affect in mind (brain) activity, this …

Comparison Of Food-Based Attractants For Bactrocera Invadens (Diptera: Tephritidae) And Evaluation Of Mazoferm - Spinosad Bait Spray For Field Suppression In Mango, Sunday Ekesi, Samira Mohamed, Chrysantus M. Tanga

All Peer-Reviewed Publications

Catches of Bactrocera invadens Drew, Tsuruta, & White (Diptera: Tephritidae) in Multi-lure traps baited with six commercial food-based attractants, Mazoferm E802, Torula yeast, GF-120, Hymlure, Biolure, and Nulure were compared in mango orchards in Kenya. In 2007, Mazoferm E802 and Torula yeast were the most effective attractants and captured 2.4-2.6 times more females and 3.4-4.0 times more males than the standard Nulure. All attractants captured more females than males (ranging from 63 to 74%). In 2008, Mazoferm E802 was the most effective bait capturing 5.6 and 9.1 times more females and males, respectively, than the standard Nulure. Among all the …

Optimal Control In The Treatment Of Retinitis Pigmentosa, Erika T. Camacho, Luis A. Melara, Cristina Villalobos, Stephen Wirkus

School of Mathematical & Statistical Sciences Faculty Publications

Numerous therapies have been implemented in an effort to minimize the debilitating effects of the degenerative eye disease Retinitis Pigmentosa (RP), yet none have provided satisfactory long-term solution. To date there is no treatment that can halt the degeneration of photoreceptors. The recent discovery of the RdCVF protein has provided researchers with a potential therapy that could slow the secondary wave of cone death. In this work, we build on an existing mathematical model of photoreceptor interactions in the presence of RP and incorporate various treatment regiments via RdCVF. Our results show that an optimal control exists for the administration …

Illinois State, February 2014, Illinois State University, University Marketing And Communications

State: The Magazine of Illinois State University (1999-present)

Illinois State University alumni magazine

Policy Makers’ Influence On The Emergence Of A New Scientific Discipline: The Case Of Nanotechnology In Ireland, Nicolas Battard

Doctoral

Science has undergone tremendous changes since World War II with the blurring of boundaries between science, government, and industry, as well as the so-called convergence of scientific disciplines. Nanotechnology is an illustrative example of this phenomenon. Boundaries between all these spheres are challenged, renegotiated, and reshaped under the influence of the multiple actors involved. I question here the extent to which nanoscience and nanotechnology (N&N) are emerging as a new scientific discipline under the influence of science and technology policies. With the study of N&N in Ireland from the late 1990s onwards, a focus is placed on both the macro-meso …

Criticality And Quenched Disorder: Harris Criterion Versus Rare Regions, Thomas Vojta, José A. Hoyos

Physics Faculty Research & Creative Works

We employ scaling arguments and optimal fluctuation theory to establish a general relation between quantum Griffiths singularities and the Harris criterion for quantum phase transitions in disordered systems. If a clean critical point violates the Harris criterion, it is destabilized by weak disorder. At the same time, the Griffiths dynamical exponent z' diverges upon approaching the transition, suggesting unconventional critical behavior. In contrast, if the Harris criterion is fulfilled, power-law Griffiths singularities can coexist with clean critical behavior, but z' saturates at a finite value. We present applications of our theory to a variety of systems including quantum spin chains, …