Digital Commons Network^™

Simulations Of Space Radiation Interactions With Materials, With Application To Dose Estimates For Lunar Shelter And Aboard The International Space Station, Tai Pham

Nuclear Engineering ETDs

This research performed simulations using the state-of-art three dimensional computer codes to investigate the interactions of space radiation with materials and quantify the biological dose onboard the International Space Station (ISS) and in a lunar shelter for future manned missions. High-energy space radiation of Trapped Protons, Solar Particle Events, and GCRs particles interactions are simulated using MCNPX and PHITS probabilistic codes. The energy loss and energy deposition within the shielding materials and in a phantom are calculated. The contributions of secondary particles produced by spallation reactions are identified. Recent experimental measurements of absorbed dose in a phantom aboard the International …

Six Elevated To Distinguished Professor, Natalie Wade

Browse All News

No abstract provided.

God's Care For Creation: An Ode To "The Little Things That Run The World", Matthew Dowling

Leaven

No abstract provided.

As-777-14 Resolution On Proposal To Establish The Strawberry Sustainability Research And Education Center, C. Kitts, J. Peterson, And M. Shelton

Academic Senate Resolutions

That the Academic Senate endorses the establishment of the Strawberry Sustainability Research Education Center.

Joint Report Of Peer Review Panel For Numeric Nutrient Criteria For The Great Bay Estuary New Hampshire Department Of Environmental Services June, 2009, Victor J. Bierman, Robert J. Diaz, W. Judson Kenworthy, Kenneth H. Reckhow

Additional Regional Technical Reports & Resources

This peer review was authorized through a collaborative agreement sponsored by the New Hampshire Department of Environmental Services (DES) and the Cities of Dover, Rochester and Portsmouth, New Hampshire. The purpose was to conduct an independent scientific peer review of the document entitled, “Numeric Nutrient Criteria for the Great Bay Estuary,” dated June, 2009 (DES 2009 Report).

Lanthorn, Vol. 48, No. 42, February 13, 2014, Grand Valley State University

Volume 48, July 1, 2013 - June 2, 2014

Lanthorn is Grand Valley State's student newspaper, published from 1968 to the present.

What’S Queer About Remy, Ratatouille, And French Cuisine?, Laure Murat

Cinema & Media Studies

This chapter appears from the book, What’s Queer about Europe: Productive Encounters and Re-enchanting Paradigms, Edited by Mireille Rosello, and Sudeep Dasgupta.

"What’s Queer about Remy, Ratatouille, and French Cuisine?" focuses on Ratatouille (2007), the story of Remy, a rat who becomes a chef. This spectacular animated movie could be read as a coming-out story, where the rat embodies the symbolic lonely gay, refined as an object of disgust, excluded and successful. Ratatouille is also a story about race, species and nationality in contemporary France. In this context, Queer studies is an appropriate tool to address a series of …

Vol.41 N.29 February 13th 2014, Brown Publishing Company

Black Voice News

No abstract provided.

The Setonian, February 13, 2014, Seton Hall University

2014

No abstract provided.

Genome-Wide Rnai Ionomics Screen Reveals New Genes And Regulation Of Human Trace Element Metabolism, Mikalai I. Malinouski, Nesrin M. Hasan, Yan Zhang, Javier Seravalli, Jie Lin, Andrei Avanesov, Svetlana Lutsenko, Vadim N. Gladyshev

Department of Biochemistry: Faculty Publications

Trace elements are essential for human metabolism and dysregulation of their homoeostasis is associated with numerous disorders. Here we characterize mechanisms that regulate trace elements in human cells by designing and performing a genome-wide high-throughput siRNA/ionomics screen, and examining top hits in cellular and biochemical assays. The screen reveals high stability of the ionomes, especially the zinc ionome, and yields known regulators and novel candidates. We further uncover fundamental differences in the regulation of different trace elements. Specifically, selenium levels are controlled through the selenocysteine machinery and expression of abundant selenoproteins; copper balance is affected by lipid metabolism and requires …

Perceived Risk Of Predation Affects Reproductive Life-History Traits In Gambusia Holbrooki, But Not In Heterandria Formosa, Shomen Kukherjee, Michael Heithaus, Joel C. Trexler, Jayanti Ray-Mukherjee, Jeremy Vaudo

Marine & Environmental Sciences Faculty Articles

Key to predicting impacts of predation is understanding the mechanisms through which predators impact prey populations. While consumptive effects are well-known, non-consumptive predator effects (risk effects) are increasingly being recognized as important. Studies of risk effects, however, have focused largely on how trade-offs between food and safety affect fitness. Less documented, and appreciated, is the potential for predator presence to directly suppress prey reproduction and affect life-history characteristics. For the first time, we tested the effects of visual predator cues on reproduction of two prey species with different reproductive modes, lecithotrophy (i.e. embryonic development primarily fueled by yolk) and matrotrophy …

Functional Interactions Between The Cannabinoid System And Memory Consolidation In The Hippocampus: A Synthesis Of Findings From Behavior, Morphology, Physiology, And Synaptic Signaling In The Rat, Felicha Candelaria-Cook

Psychology ETDs

The hippocampus is essential for long-term memory storage and consolidation. The dentate gyrus acts as a gateway into the hippocampal formation, specifically with reference to medial and lateral perforant path projections from the entorhinal cortex. The dentate gyrus and the hippocampus contain a high density of cannabinoid receptors and may be a key location in which cannabinoids exert influence to disrupt memory. Administration of a cannabinoid agonist often leads to short-term and long-term memory deficits in a variety of tasks. Cannabinoids can impair memory acquisition, task performance, along with memory consolidation and retrieval mechanisms. Endogenous cannabinoids are retrograde messengers involved …

The Montclarion, February 13, 2014, The Montclarion

The Montclarion

Student Newspaper of Montclair State University

A Student Assessment In Value Of Cooperative Education Curriculum Integrated Through Character Development: The Greenwood School, Rebecca Clarke

Capstone Collection

Cooperative education programming as a model of teaching to varied learning styles, is based on a small scale school working to teach children to their specific learning styles centered around their brain function strengths and limitations. The Greenwood School is a boarding school located in Putney, VT specializing in teaching boys with academic, social, and behavioral differences. The school caters to about fifty boys from ages ten to eighteen. Within all of the programs operating on this campus, one of the newest is the internship program, which offers off-campus, community based work learning opportunities with adult mentors and small business …

Flyer News, Vol. 61, No. 18 (Feb. 13, 2014), University Of Dayton

Flyer News

Student-run newspaper of the University of Dayton.

Locating Resistance To The Tomato Virus Disease “Tomov” With Rflp Markers On Chromosome 6, Heidi Lynn Stevens-Robbins, Dr. Eric N. Jellan

Journal of Undergraduate Research

Tomato yellow leaf curl virus (TYLCV) and tomato mottle virus (ToMoV), are both geminiviruses, and are considered major limiting factors in the commercially grown tomato (Lycopersicon esculentum Mill.) in Florida and the Middle East (1). These viruses have been identified as reducing yields and/or reducing fruit quality in an infected crop. TYLCV appears to have originated in Old World and has been recently identified in Florida (1). ToMoV was originally identified in Florida and has since been found throughout the Southeastern United States (2).

The Effects Of Prenatal Phytoestrogen Exposure On Fetal Brain Calbindin Levels, Heather Taylor, Dr. Edwin Lephart

Journal of Undergraduate Research

Calcium plays a major part in muscle contraction, bone growth, but especially in central nervous system (CNS) development and function. Calcium participates in neuronal growth and degeneration. For example, the CNS depends on calcium during the development of neuronal cytoskeletal structures and synapse formation. When there is an excess of calcium, it disrupts the formation and the essential synapses or connections and they fail to form correctly.

The Pan American (2014-02-13), Susan Gonzalez

UTPA Archives - The Pan American Newspaper

Vol. 70, No. 19

Effects Of Prematurity On The Presence Of Weibel-Palade Bodies In Human Umbilical Vein Endothelial Cells In Situ, Niloufar Tabatabeai, Dr. John S. Gardner

Journal of Undergraduate Research

Newbom, premature infants have greater susceptibility to infection compared to older newborn infants. Although the reason for greater susceptibility to bacterial infection in premature infants is unknown, there are many reports that focus on neutrophils as the defective cell type in the immature neonatal system. However, it was recently reported by Lorant et al. that in a rat model of inflammation, neutrophils from adult rats failed to migrate efficiently in neonatal rats.’ Furthermore, we found that this defect was associated with decreased expression of Pselectin on the surface of neonatal endothelial cells in situ.

Phylogeny Of The Order Siphonaptera Based On Molecular Data, Alison Swindle, Dr. Michael F. Whiting

Journal of Undergraduate Research

The insect order Siphonaptera (fleas) has been historically significant for thousands of years. Beginning as early as 430 B.C. outbreaks of the bubonic plague have swept across continents and killed millions of people. Before fleas were linked with the plague, they were a little known order. Karl Linne recognized only two species of fleas in his “Systemae Naturae” in 1735. From 1735 to 1897 the described species count increased slowly from two up to sixty-eight. After 1897, and the recognition that fleas may be carriers of the plague, there was a rapid escalation in the research and interest in the …

Chanticleer | February 13, 2014, Jacksonville State University

Chanticleer

No abstract provided.

The Cowl - V.78 - N.15 - Feb 13, 2014

The Cowl

The Cowl - student newspaper of Providence College. Volume 78 - No. 15 - February 13, 2014. 32 pages.

Wsu Board Of Trustees Meeting Minutes, February 13-14, 2014

Board of Trustees Minutes

Minutes from the Wright State University Board of Trustees Meeting held on February 13-14, 2014.

Computational Design Of The Affinity And Specificity Of A Therapeutic T Cell Receptor, Brian G. Pierce, Lance M. Hellman, Moushumi Hossain, Nishant K. Singh, Craig W. Vander Kooi, Zhiping Weng, Brian M. Baker

Molecular and Cellular Biochemistry Faculty Publications

T cell receptors (TCRs) are key to antigen-specific immunity and are increasingly being explored as therapeutics, most visibly in cancer immunotherapy. As TCRs typically possess only low-to-moderate affinity for their peptide/MHC (pMHC) ligands, there is a recognized need to develop affinity-enhanced TCR variants. Previous in vitro engineering efforts have yielded remarkable improvements in TCR affinity, yet concerns exist about the maintenance of peptide specificity and the biological impacts of ultra-high affinity. As opposed to in vitro engineering, computational design can directly address these issues, in theory permitting the rational control of peptide specificity together with relatively controlled increments in affinity. …

Ube3a Role In Synaptic Plasticity And Neurodevelopmental Disorders.The Lessons From Angelman Syndrome., Irina Filonova

USF Tampa Graduate Theses and Dissertations

Angelman Syndrome (AS) is a severe neurodevelopmental disorder that affects 1:12000 newborns. It is characterized by mental retardation, delayed major motor and cognitive milestones, seizures, absence of speech and excessive laughter. The majority of AS cases arise from deletions or mutations of UBE3A gene located on the chromosome 15q11-13. UBE3A codes for E3-ubiquitin ligase that target specific proteins for degradation. To date, a wide variety of Ube3a substrates has been identified. The accumulation of Ube3a-dependent proteins and their effect on the multitude of signal transduction pathways are` considered the main cause of the AS pathology. While the majority of research …

Microelectrode Array For Capacitive Transduction Of Retinal Responses, Brittany Branch

Nanoscience and Microsystems ETDs

Neural degenerative diseases and traumatic injuries to the eye affect millions of people worldwide, motivating the development of neural prosthetic interfaces to restore sensory or motor function in affected individuals. Advances in neural sensing and stimulation interface technology will allow a more comprehensive understanding of neural function while leading to the development of hybrid biological-electronic sensor devices for robust, functioning neural prosthetic systems. Current techniques of neural activity sensing employ multi-electrode arrays (MEAs) that typically incorporate metal electrodes and measure currents via an electrochemical junction, leading to corrosion and charge transfer across the electrode-tissue interface. High-density neural interface technology will …

Development Of Synthetic Polymers For Bone Tissue Engineering: Engineering The Degradation Rate, Kirsten Cicotte

Biomedical Engineering ETDs

In this work the development, synthesis, and characterization of biodegradable synthetic polymers, poly (butylene fumarate) (PBF) and the copolymer poly (butylene fumarate)-co-(butylene maleate) (PBFcBM) is described. The unsaturated linear polyesters were synthesized via two synthetic routes, including an acid catalyzed transesterification reaction of (Z)-4-((4-hydroxybutan-2-yl)oxy)-4-oxobut-2-enoic acid which was formed via a ring opening reaction of maleic anhydride with 1,3-butylene glycol (BG) and reacting the acid chlorides, maleoyl chloride (MCl) and fumaryl chloride (FCl) with BG. Both methods introduce the cis (maleate) functionality into the polymer backbone, however a controlled fumarate to maleate ratio was only obtained via the acid chloride starting …

The Roddey Mcmillan Record - February 13, 2014, Winthrop University

The RMR 2010-2019

The Roddey McMillan Record (RMR) is Winthrop’s monthly multicultural student publication. The RMR has been a significant voice of the minority population of the Winthrop community since its creation by Gail Harris in April 1986. It promotes awareness and understanding of issues concerning minorities for the prosperity of the entire Winthrop community. The purpose of the RMR is to shine light on the many diverse cultures at Winthrop, focusing on issues, concerns and happenings of those who represent the multicultural community on campus. The Roddey McMillan Record is named after Dr. Cynthia Roddey and Atty, Sheila McMillan. Cynthia Roddey was …

Minutes From The February 13, 2014 Meeting Of The University Of Montana Faculty, University Of Montana--Missoula. Faculty

University of Montana Faculty Senate Meeting Minutes

Meeting minutes from the February 13, 2014 meeting of the University of Montana faculty.

Application Of Multiple Kernel Learning On Brain Imaging For Mental Illness Characterization, Eduardo Jose Castro Witting

Electrical and Computer Engineering ETDs

Mental disorders are diagnosed on the basis of reported symptoms and externally observed clinical signs. Nonetheless, these cannot be evaluated by means of clinical tests. This is the case for schizophrenia, a complex disease characterized by perturbations in language, perception, thinking, social relationships and will that affects about 1% of the U.S. population. Besides the absence of an objective assessment of symptoms to diagnose schizophrenia, not even a set of symptoms that uniquely characterize this disorder have been found. Given the absence of a biologically-based diagnosis of schizophrenia, several studies have used different brain imaging techniques in an attempt to …