Digital Commons Network^™

Table 1 - Gregoricka & Ullinger 2026, Lesley Gregoricka, Jaime Ullinger

Gregoricka et al. 2026 AJBA

No abstract provided.

Educational Efficacy Of Training Videos And Simulators For Teaching Basic Mouse Experimental Skills To Novice Veterinary Students., Atsushi Tsukamoto, Thum Su Zan, Makie Nitta, Hiromitsu Yoshida, Hirotaka Katahira, Yoshiharu Fujita, Satoshi Takagi, Shinichiro Nakamura

Faculty Research 2026

Alternative educational tools, such as training videos and simulators, are recommended in the education of laboratory animal science. However, evidence supporting their educational utility in the training of rodent experimental techniques remains limited. In this study, we assessed the utility of alternative educational tools in the practice of laboratory animal science for novice veterinary students. 149 students participated in a stepwise program beginning with lectures, followed by preparatory learning sessions using training videos and two types of mouse simulators (a silicone-based model and fabric toy mouse), and then hands-on training with live mice. The program covered basic techniques: habituation, restraint, …

Overcoming Egfr-Mediated Dendritic Cell Dysfunction To Enhance Anti-Tumor Immunity In Egfr-Mutant Nsclc By Precisely Targeting Cd73 With Ph-Responsive Nanocarriers., Xiaoling Shang, Xudong Geng, Zixu Wang, Shumin Yuan, Shanshan Ding, Ni Liu, Xinchun Ma, Xuan Sun, Huimin Wang, Ying Sun, Xun Qu, Guangwen Ren, Yong Qiang Li, Xiuwen Wang, Yanguo Liu

Faculty Research 2026

EGFR mutations remain a major challenge in immunotherapy for non-small cell lung cancer (NSCLC), with poor responses to immune checkpoint inhibitors driven by mechanisms associated with EGFR mutation-mediated tumor microenvironment (TME) modulation. This study reveals that EGFR mutations prominently impaired dendritic cell (DC) maturation, disrupting their capacity to effectively prime CD8+ T cells and thereby compromising anti-tumor immune responses. By application of clinical specimen analyses, multi-omics approaches, and in vivo mouse models, this work demonstrates that EGFR mutations elicited adenosine production through the ERK/c-Jun signaling axis in tumor cells, establishing an immunosuppressive TME that impeded maturation and antigen presentation of …

Metallothionein 1 Mediates Growth And Survival Of Dnmt3a;Npm1-Mutant Acute Myeloid Leukemia, Patricia A Colom Díaz, Jayna J Mistry, Kira Young, Chih-Hsing Chou, Nathan Boyer, Ross L Levine, Nathan Salomonis, H Leighton Grimes, Jennifer J. Trowbridge

Faculty Research 2026

No abstract provided.

Growth And Development Of Lettuce And Mizuna Under Urrm-Representative Conditions, Claudia Garrido-Ruiz, Bruce Bugbee, Juan D. González-Teruel, Alexandra Cartwright, Scott B. Jones

NASA

The Utah Reusable Root Module (URRM) is a zero-discharge plant growth system under development for operation in microgravity aboard the International Space Station. Qualification of the URRM requires defining expected crop performance under representative operating conditions to evaluate nominal biological behavior. This study presents experimental results documenting the growth of mizuna (Brassica rapa var. japonica) and Outredgeous lettuce (Lactuca sativa L.) under URRM-representative conditions defined by the use of a silicone rubber fringe top cover for root-zone containment. 

Ground-based experiments were conducted using the Greenhouse System, URRM Simulator – Replicate 1, and URRM Simulator – Replicate 2, …

Winter 2026, Humayun Islam

PMI Newsletter

No abstract provided.

2025-2026 Common Data Set, Southwestern Oklahoma State University

Common Data Sets

This document contains data compiled by the SWOSU Office of Institutional Research for the 2025-2026 academic year.

Integrating Domain Knowledge And Machine Learning In Rice Cultivation: A Case Study Of Algeria, Sara Faruqui, Jenna M. Handal, Navi Gill Dhillon

Bioinformatics

Research has highlighted Artificial Intelligence (AI) as a promising solution to mitigate the threat of food insecurity. Rice, a staple in the global diet, is particularly vulnerable to heat stress caused by climate change. The challenges of climate change, population growth, and increased famine risk may be alleviated through the implementation of AI models in rice cultivation. For decades, agricultural workers have faced the dilemma of needing to increase crop yields while dealing with dwindling resources and the need for more efficient practices. AI models, however, are limited by the quality and scope of the data they receive. Integrating domain …

Unveiling Microplastic Removal And Characteristics In Wastewater From Two Municipal Wastewater Treatment Facilities In Indonesia, Nurul Setiadewi, Prayatni Soewondo, Cynthia Henny

Applied Environmental Research

Wastewater treatment plants (WWTPs) are considered an entrance pathways for microplastic (MP) pollution in aquatic environments. This study reveals the removal and characteristics of MPs in wastewater from two municipal WWTPs in Indonesia. The influent contained 17.1 ± 5.65 particles L-1 (WWTP A) and 15.45 ± 4.31 particles L-1 (WWTP B), whereas the effluent contained 1.41 ± 0.01 and 1.5 ± 0.16 particles L-1. The removal efficiency was 91.75% for WWTP A and 90.32% for WWTP B, with no statistically significant difference (p > 0.05). WWTP A employed advanced treatment units, whereas WWTP B used a conventional pond-based system. MPs were …

Untangling Ai Openness, Parth Nobel, Alan Rozenshtein, Chinmayi Sharma

Articles

The debate over AI openness—whether to make components of an artificial intelligence system available for public inspection and modification—forces policymakers to balance innovation, democratized access, safety, and national security. By inviting startups and researchers into the fold, it enables independent oversight and inclusive collaboration. But technology giants can also use it to entrench their own power, while adversaries can use it to shortcut years and billions of dollars in building systems, like China’s DeepSeek, that rival our own. How we govern AI openness today will shape the future of AI and America’s role in it.

Policymakers and scholars grasp the …

Nanocomposite Mediated Delivery Of 5-Fluorouracil Using Silver Nanoparticles To Promote Wound Healing, Kamal Nath Kasi

Theses, Dissertations and Capstones

Chronic wounds, particularly in diabetic patients, remain a significant clinical challenge due to the complex interaction of persistent infection, chronic inflammation, and impaired cellular regeneration. Conventional drug therapies often fail to achieve effective treatment due to rapid drug degradation, poor targeting, and localized toxicity. This study explores a nanotechnology-based approach by developing and evaluating 5-FU loaded AgNP (AgNP–5FU) as a controlled drug delivery system. AgNP (AgNP) were synthesized and characterized using scanning electron microscopy (SEM), energy dispersive X-ray (EDX) analysis, particle size, and zeta potential analysis, while Fourier Transform Infrared Spectroscopy (FTIR) analysis suggested possible interaction between 5-FU and the …

Development And In Vitro Characterization Of 5-Fluorouracil–Loaded Plga Nanoparticles For Controlled Drug Delivery, Kavya Yandapalli

Theses, Dissertations and Capstones

Non-Alcoholic Fatty Liver Disease (NAFLD) is a progressive metabolic disorder characterized by excessive lipid accumulation in hepatocytes and chronic inflammation. Nanoparticle-based drug delivery systems offer a promising strategy to enhance therapeutic efficacy while minimizing systemic toxicity. The objective of this study is to formulate and characterize 5-FU–loaded PLGA nanoparticles and evaluate their in vitro performance. 5-FU–loaded PLGA nanoparticles were prepared using the double emulsion solvent evaporation method. The nanoparticles were characterized by particle size, polydispersity index, zeta potential and SEM. Drug encapsulation efficiency, loading capacity and in vitro drug release studies were conducted. The formulated nanoparticles exhibited sizes within the …

Comparative Machine Learning Models For Disease Risk Prediction, Mercy Mawusi Agbley

Theses, Dissertations and Capstones

Accurate prediction of disease outcomes is crucial for improving clinical decision-making and enabling early intervention. This study compares the performance of various statistical and machine learning models for clinical risk prediction using two healthcare datasets: diabetic retinopathy and heart disease. The models assessed include Logistic Regression, LASSO, k-Nearest Neighbors (KNN), Support Vector Machines (SVM), Neural Networks, Random Forests, Gradient Boosting Machines (GBM), and a stacked ensemble model. Prior to modeling, datasets were split into train and test sets. Standardization was applied to numeric features whilst categorical features were one-hot encoded. These transformations were later applied to the test set. Principal …

Hepatocyte Peroxisome Biogenesis And Phytol-Induced Metabolic Stress In Liver Disease, William Galloway

Theses, Dissertations and Capstones

Hepatocyte peroxisomes are required for metabolism of phytol-derived branched-chain fatty acids through the ACOX2-SCPx beta-oxidation pathway. This study tests whether hepatocyte-specific deletion of PEX16 (Pex16^Alb-Cre), which eliminates peroxisome biogenesis, sensitizes the liver to phytol-induced injury. The Pex16^Alb-Cre mice and their normal control Pex16^fl/fl mice were fed the Lieber-DeCarli liquid with or without 0.1 percent phytol for eight weeks. Serum alanine aminotransferase (ALT) and liver index were measured. Liver sections were stained with hematoxylin and eosin and Masson’s trichrome. Immunoblot analysis of peroxisomal enzyme expression was also performed. Phytol had no effect in Pex16^fl/fl mice as …

Anaerobic Digestion Of Variable, Heterogeneous Organic Wastes Under Changing Operational Conditions And Bioaugmentation: Impacts On Process Performance And Microbiome Dynamics, Victoria Holliday

Theses and Dissertations--Biosystems and Agricultural Engineering

Expanding the adoption of anaerobic digestion (AD) is limited by system instabilities caused by feedstock composition and variability. Understanding how changes in feedstock and operational parameters influence microbiome dynamics is essential for developing biology-driven strategies to improve digester stability.

Two semi-continuous reactors, an experimental and a control, operated over 39 weeks across five phases with varying feedstocks and organic loading rates. Substrate-specific enrichment cultures were developed for bioaugmentation and implemented in select phases to assess its impact. Both reactors exhibited similar performance, transitioning through periods of stability, stress, and recovery in response to operational changes. Corresponding shifts in dominant taxa …

Investigating The Viability Of Fully Online Asynchronous Physics Instruction In Formal Education, Clifton W. Massey-Noel

Physics Dissertations

In this dissertation we present results from two consecutive investigations into the fully online asynchronous modality in Physics Education. We first discuss the efficacy of a fully online asynchronous section of Modern Physics held in Fall 2024. The asynchronous section is compared with four prior partially-flipped sections of the same class, two of which were held in-person, and two of which were held synchronously online. Results suggest that all three modalities can be made to be about equally as effective. We also discuss the efficacy of a fully online asynchronous section of Calculus-Based Introductory Mechanics held in Fall 2025. The …

Sexually Dimorphic Effects Of Gpnmb Modulation On Vertebral Bone Mass Regulation And Intravertebral Disc Health, Hakem Altawil, Fayez Safadi

Williams Honors College, Honors Research Projects

Osteoporosis and vertebral degeneration are major contributors to musculoskeletal morbidity, yet the molecular mechanisms regulating vertebral bone and intervertebral disc (IVD) homeostasis remain incompletely understood. GPNMB (osteoactivin) has been identified as a regulator of bone remodeling, though its role in spine health is unclear. This study evaluated the effects of GPNMB deficiency on lumbar vertebral bone microarchitecture and IVD integrity in a sex-dependent context.

Six-month-old male and female wild-type (WT) and GPNMB knockout (KO) mice were analyzed using micro–computed tomography (µCT) of lumbar vertebrae (L4–L6) and histological assessment of the L5–L6 IVD. KO males exhibited increased bone volume fraction, bone …

Innocence Interrupted: A 25-Year Study Of Reported Filicide Incidents In The United States, 1999 To 2023, Jeffrey A. Walsh, Jessie L. Krienert, Ema Voksic

Faculty Publications - Criminal Justice Sciences

This study examines filicide, the killing of a child by a parent or parental figure, using 25 years of data (1999–2023) from the National Incident-Based Reporting System (N = 3,974). Multinomial logistic regression was used to analyze variations in offender, victim, and incident characteristics across four victim age categories: neonaticide (within 24 hr of birth), infanticide (1–364 days), child filicide (1–17 years), and adult filicide (18+ years). Results reveal significant differences in offender age, sex, race, weapon use, and victim demographics. Neonaticide is most often associated with younger female offenders and the use of personal weapons, while adult filicide …

Reading Wars, Don Herzog

Books

Once again, we’re fighting wars over reading. Who gets to read? What do they get to read? These days, the right is obsessed with removing LGBTQ books from school and public library shelves and ensuring students read only the Correct version of American history. The left is obsessed with eradicating right-wing fantasies, not to mention outright lies, from the internet, and with airbrushing or even purging racist texts. You don’t have to stoop to whataboutery to notice a suspicious resemblance. But once again is wrong. We’ve always fought these wars, even if the enemies come and go. In this book, …

Covering The Care: The Fourth Trimester, Susy Hawes

All Materials

The weeks following the birth of a baby are often described as a time of extremes: profound joy paired with deep exhaustion, vulnerability, and adjustment. For birthing people, this period involves physical recovery from childbirth, dramatic hormonal shifts, disrupted sleep, learning to feed and care for an infant, and navigating major emotional changes. While some new parents have strong support systems, others face isolation, housing instability, or unsafe home environments. This critical 12-week period after birth is now widely known as the “fourth trimester.” Although the language is new, the reality is not. Across cultures and history, the postpartum period …

Retrospective Analysis And Glp-1 Usage And Thyroid Cancer, Kyle Distler, Suzanne Martinez, Des'ree Garvin, Aysu Erdemir, Jyoti Moorjani, Jean Ramos Cardona, Patrick Bailey, Jacqueline Gilmore

South Atlantic Division GME Research Days 2026

No abstract provided.

Reading Between The Lines: Representations Of Dyslexia In Young Adult Literature, Carli B. Gauvin

Honors Theses and Capstones

While dyslexia affects upwards of 20% of the population, this learning disability is not commonly brought up in young adult literature. This lack of representation negatively impacts those with dyslexia, who often fail to find themselves in the books they read, and readers in general, who are given fewer opportunities to gain insight into the learning disability. Young adult books that do discuss dyslexia can be at risk of portraying the learning disability in an unfavorable light, which can make dyslexic readers feel undervalued in society and can introduce misconceptions about dyslexia to all readers. It is crucial to analyze …

The Lie Group Basis Of Neuronal Membrane Architecture: Why The Hodgkin–Huxley Equations Take Their Form, Robert Melendy, Daniel Blue

Faculty Publications - Department of Electrical Engineering and Computer Science

The Hodgkin–Huxley equations have successfully described neuronal excitability for over seventy years, yet their mathematical structure remains empirically justified rather than theoretically explained. Why are gating variables bounded between 0 and 1? Why does sodium conductance depend on m³h rather than other combinations? Why does potassium depend on n⁴? Why do all rate functions contain exponential voltage dependencies? Why are the kinetics first-order? We demonstrate that these structural features arise naturally from three fundamental physical symmetries governing ion channel dynamics: the compactness of conformational state space, the scaling invariance of membrane conductance, and temporal translation invariance. …

Commencement Program (Spring 2026), Csusb

CSUSB Commencement Programs

No abstract provided.

Cultural Logics In Agriculture: A Critical Christian Perspective, John Hill Price, Travis Ryan Pickell, Paul Capel, Kyungsoo Yoo, Dominic Christiensen, Marie Culhane, Tyler Dick, John Deen, Erik Watkins

Faculty Publications - George Fox School of Theology

Imagine a precocious, driven, and empathetic undergraduate student. She has discovered a passion and a talent for biochemistry, and wants to apply to graduate school to pursue agronomy, with the goal of returning to her rural community home after graduation. She loves science and nature; she is also a committed Christian. She has a vague sense that these things are connected, but she isn’t sure how. And to be honest, the people around her in college do not always believe these two parts of her identity are compatible. Nevertheless, she plans to pursue graduate studies and hopes her faith will …

Advancing Lipidomics Through Fluoroalcohol-Induced Multiphase Fractionation And Orthogonal Lc×Lc–Ms Detection, Md Al Amin

Chemistry & Biochemistry Dissertations

Comprehensive characterization of the lipidome remains a significant analytical challenge due to the immense structural diversity, wide dynamic range, and complex physicochemical continuum of lipid species. Conventional extraction methods, such as those by Bligh–Dyer and Folch, and one-dimensional liquid chromatography (1D-LC) often fail to resolve this complexity, leading to chromatographic overlap, severe ion suppression, and limited coverage of low-abundance or highly hydrophobic species. This dissertation addresses these bottlenecks by establishing a separation-driven analytical framework that integrates novel fluoroalcohol-induced multiphase systems (FAiTPS) with orthogonal multidimensional liquid chromatography–mass spectrometry (LC×LC–MS).

The core of this research is the development and physicochemical characterization of …

He Rengao Super-Consciousness Imagery, A Global Touring Exhibition, Jun Dong

MA Projects

Focusing squarely on He Rengao’s long-developed visual philosophy, this exhibition will take the form of a solo presentation introducing Super-Consciousness Imagery to New York audiences. As one of China’s most established contemporary artists, He has spent decades refining a highly introspective and philosophically grounded painterly language. This exhibition aims to situate his mature body of work within an international conversation, foregrounding painting as a site where civilizational imagination, spiritual inquiry, and aesthetic experimentation converge. The exhibition title, Super-Consciousness Imagery, encapsulates two key elements central to He’s artistic practice; it refers to the expanded state of awareness the artist seeks to …

Raining Plastics: Quantification Of Atmospheric Deposition Of Plastic And Anthropogenic Particles Into An Estuary Of National Significance With The Assistance Of Citizen Scientists, Linda Walters, Madison Serrate, Tara Blanchard, Paul Sacks, Fnu Joshua, Lei Zhai

Research Data and Datasets

Globally, little is known about the dispersal of microplastics (MP) and anthropogenic particles (AP) via atmospheric deposition (AD) into water bodies. Correlating AD to the large number of MP in estuaries is challenging but an important first step toward reducing this form of pollution. A previously published model of the surface waters of the Indian River Lagoon (IRL, east central coast of Florida, USA) estimated it contained 1.4 trillion microplastics. To determine if AD could produce this much plastic deposition, we deployed passive AD collectors throughout a 145 km2 area at three site types with assistance from citizen scientists. We …

Spieltrieb, Edward F. Newcomb

College of Graduate Studies: Theses & Dissertations

This thesis investigates the creative and pedagogical intersections of nostalgia, play, and neurodivergent experience through a mixed-media studio practice. Grounded in Friedrich Schiller’s concept of Spieltrieb—the human drive to play as a balance between sensual and rational impulses—this work explores how childhood memory, instinct, and impulsive mark making inform both artistic production and art education.

Drawing on theoretical frameworks by Susan Sontag and John Berger, the work resists overinterpretation in favor of sensory immediacy, inviting viewers into direct, embodied encounters with material form. Sontag’s critique of mimetic representation and Berger’s analysis of reproducibility and context inform a practice that …

Crispr Transgenic Clytia Hemisphaerica As A Vector For Toxin Delivery In A Zebrafish Melanoma Model, Theodore G. Paz

Theses, Dissertations and Culminating Projects

The jellyfish Clytia hemisphaerica has the potential to be used in cancer therapies with the discovery of potential active toxin target regions to be modified for use. The program Venomix is a Uniprot-based database that was utilized in this experiment to generate likely flagged hit regions using Clytia hemisphaerica CDS files run against its database of terrestrial toxins (Furuno et al., 2003; Macrander et al., 2018). By themselves they are indeterminate as to whether they are active toxin region hits (Macrander et al., 2018). With further analysis such as toxin homology in closely related, annotated marine taxa and accounting for …