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Cultural Capital And The Family-School Mesosystem : A Multiple Groups Analysis Of School-Based Parent Involvement Types And Their Relations With Early Student Achievement., Emily R. Dickinson 1974-

Electronic Theses and Dissertations

This dissertation study explored the relationship between school-based parent involvement and early reading outcomes by positing that different types of parent involvement activities reflect access to different forms of cultural capital and therefore should be analyzed as separate constructs. Exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) techniques were used to establish the factor structure underlying measures of school-based parent involvement available in the Early Childhood Longitudinal Study-Kindergarten Cohort of 2011 (ECLS-K: 2011). Also of interest were the variations in the amount of participation in different types of involvement between families from various sociocultural backgrounds, as well as the …

Competitive Evaluation Of Data Mining Algorithms For Use In Cassification Of Leukocyte Subtypes With Raman Microspectroscopy, Adrian Maguire, I. Vega-Carrascal, Jane Bryant, Lisa White, Orla Howe, Fiona Lyng, Aidan Meade

Articles

Raman microspectroscopy has been investigated for some time for use in label-free cell sorting devices. These approaches require coupling of the Raman spectrometer to complex data mining algorithms for identification of cellular subtypes such as the leukocyte subpopulations of lymphocytes and monocytes. In this study, three distinct multivariate classification approaches, (PCA-LDA, SVMs and Random Forests) are developed and tested on their ability to classify the cellular subtype in extracted peripheral blood mononuclear cells (T-cell lymphocytes from myeloid cells), and are evaluated in terms of their respective classification performance. A strategy for optimisation of each of the classification algorithm is presented …

Pathogenic Role Of Acrolein In Alcoholic Liver Disease., Wei-Yang (Jeremy) Chen

Electronic Theses and Dissertations

Alcohol is the most socially accepted addictive drug, and it can cause alcoholic liver disease (ALD), which is a major cause of morbidity and mortality in the United States and worldwide. Animal and human studies demonstrate that chronic alcohol consumption causes a pro-oxidant environment in the liver and increases hepatic lipid peroxidation and the accumulation of by-products such as acrolein and 4-hydroxynonenal. Acrolein is the most reactive and toxic aldehyde generated through lipid peroxidation. Also, acrolein is a major component of cigarette smoke, and there is increasing evidence that smoking negatively impacts the incidence, severity, and clinical course of chronic …

Pathogenic Role Of Phosphodiesterase 4 (Pde4) In The Development Of Alcohol Induced Hepatic Steatosis., Diana Veronica Avila

Electronic Theses and Dissertations

Alcohol induced hepatic steatosis is a significant risk factor for progressive liver disease. Steatotic hepatocytes have increased sensitivity to injury produced by inflammatory cytokines, particularly TNF. Cyclic adenosine monophosphate (cAMP) has been shown to play a significant role in the regulation of both TNF production and lipid metabolism. However, the role of altered cAMP homeostasis in alcohol mediated hepatic steatosis and injury has not been studied. cAMP levels are tightly regulated by phosphodiesterase family of enzymes. Our recent work demonstrated that increased expression of hepatic PDE4, which specifically hydrolyzes and decreases cAMP levels, plays a pathogenic role in the development …

Prompting Discussion : Writing Prompts, Habits Of Mind, And The Shape Of The Writing Classroom., William Matthew Wiles

Electronic Theses and Dissertations

Much of the important writing students will be tasked with in their college careers calls upon them to approximate the writing styles academics and professionals use to shape and advance their respective fields. Many disciplinary values are encoded within the such texts. Learning these styles can be difficult for students who lack the experience and ingrained habits that their instructors may take for granted. In most cases, college writers are outsiders peeking in from the outskirts of academic and professional discourse. Also, the “Expert Blind Spot” (Ambrose et. al) can make college instructors oblivious to the nuances of the writing …

Novel Analytical Tools For Studies In Molecular Assemblies : I. Electro-Active Single-Mode Integrated Optical Waveguides ; Ii. Coupled Plasmon Waveguide Resonances., Xue Han

Electronic Theses and Dissertations

Two optical analytical tools were developed for studying molecular assemblies at solid/liquid interfaces. Electro-active single-mode integrated optical waveguide (EA-SM-IOW) technology was developed as a platform for spectroelectrochemical investigations on redox adsorbates at the sub-monolayer level. With an optimized ultra-thin indium tin oxide film combined with a single-mode integrated optical waveguide, for the first time, a more than 14,000 times higher sensitivity (compared to conventional potential-modulated transmittance) was achieved. From optical signals, this technique was able to reconstruct electrochemical information of redox adsorbates, including the formal potential and the electron transfer rate. A few major advantages were achieved with the developed …

The Impact Of Inflammatory And Immune Response-Related Genetic Variants On Prostate Cancer Risk Among Men Of African Descent., Dominique Zilpha Jones

Electronic Theses and Dissertations

Background: In the U.S., prostate cancer (PCA) metastasis is associated with a 5-yr survival rate of 29% and disproportionately affects men of African descent. Single nucleotide polymorphisms (SNPs) may serve as genetic markers to identify individuals at high risk of developing PCA. Methods: We examined main and joint effects of 119 inflammatory and immune response-associated SNPs among men of African descent (535 controls, 279 cases) via logistic regression (LR) and entropy-based-multi-factor dimensionality reduction (MDR) modeling. Results: MDR yielded highly synergistic [(TLR10, TLR6 and IRF3), (TLR2, IRAK4), (IL1R2, IL10, IL10RA)] interaction …

Modulation Of The Ovarian Cancer Humoral Response By Tumor-Derived Exosomes., Carolyn Denise Roberson

Electronic Theses and Dissertations

The pathogenesis of epithelial ovarian cancer is complicated by its diagnosis during the latter stages of the disease resulting from lack of symptoms or from presence of symptoms that mimic other conditions. Because of the often fatal prognosis by the time of actual detection, efforts are being made to better understand the host immune response to ovarian cancer. In this study, the contributions of the humoral immune response were investigated by focusing on the role of tumor-derived exosomes and their ability to modulate humoral immune responses. First, ovarian cancer patient-derived free circulating antibodies were investigated for immunoreactivity to patient antigen. …

The Use Of Surface Cytokines As Biomarkers In B Cell Mediated Autoimmune Diseases, Abby Jones Weldon

Loma Linda University Electronic Theses, Dissertations & Projects

RA and SLE are B cell-mediated autoimmune diseases dominated by autoantibodies that affect over 1.5 million Americans. Together RA and SLE contribute to over 29 billion in healthcare costs, therefore due to the high financial burden and physical toll of these diseases on the population, there is a critical need to effectively and efficiently diagnose and treat RA and SLE patients. The aim of our studies was to identify biomarkers and drug targets to improve the identification and treatment of RA and SLE patients. As discussed above, APRIL, BAFF and TSLP have been implicated in the pathogenesis of RA and …

The Effect Of Grapes In Mice With Alzheimer's Disease And Brain Injury, Nikita Mistry

Loma Linda University Electronic Theses, Dissertations & Projects

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder resulting in cognitive and memory deficits and deposits of amyloid beta (Aβ) in the cortex and hippocampus are thought to be significant contributors to the disease process. Increasing evidence suggests that foods rich in polyphenols, such as pomegranates and grapes, may have neuroprotective effects in both rodents and humans. Our previous research has shown that a pomegranate-enriched diet decreased Aβ plaque load and improved behavior in Tg2576 mice. In this study, we determined whether a grape-enriched diet altered Aβ neuropathology and TBI in PSAPP mice. Mice received either craniotomy or a moderate …

Modulation Of T Lymphocytes By Tumor-Released Survivin, Jessica Marie Jutzy

Loma Linda University Electronic Theses, Dissertations & Projects

The tumor microenvironment is an area of intense interaction between normal and malignant cells. Factors and cell types within this environment can play a crucial role in the progression or regression of the tumor. Of primary interest are tumor-infiltrating T lymphocytes, which have been shown to have a key role in modifying the dynamics of the tumor microenvironment to promote or prevent tumor growth. While there is much in vitro and in vivo evidence for a modification of the tumor infiltrating T cell population toward a pro-tumor environment, what induces these changes within the tumor microenvironment has remained elusive. Our …

Risk Factors For Substance Use In The American Indian/Alaska Native Community, Kelli Lewis Rugless

Loma Linda University Electronic Theses, Dissertations & Projects

Research has indicated that substance use is a significant problem in the American Indian/Alaska Native adolescent community. What is less understood are the risk and protective factors specific to this community. Using data available from the Communities That Care Youth Survey, we analyzed risk and protective factors for current (30-day) and lifetime use of smokeless tobacco, cigarettes, alcohol, marijuana, and alcohol in a sample of 5,912 AI/AN adolescents. Logistic regression analyses were used and our findings indicated that peer and family influences, as well as ease of access to alcohol and other drugs had the greatest overall impact on AI/AN …

Aberrant Neurogenic And Epigenetic Processes Are Associated With Depression Induced By Developmental Arsenic Exposure, Christina René Tyler

Biomedical Sciences ETDs

Arsenic is a pervasive environmental contaminant derived from both natural and anthropogenic sources. Epidemiological evidence supports a correlation between arsenic exposure in drinking water and increased rates of psychiatric disorders, including depression, in exposed populations. Previous studies have established that perinatal exposure to arsenic (through all three trimesters of fetal/neonatal development, DAE) has long-lasting consequences into adulthood including deficits in learning and memory, molecular aberrations in the hypothalamic-adrenal-pituitary (HPA) axis, and depressive-like symptoms in mice. The studies described in this dissertation were designed to assess the impact of DAE on adult hippocampal neurogenesis (AHN) as a possible mechanism of action …

The Role Of Mir-137 In Schizophrenia, Carrie Leigh Wright

Biomedical Sciences ETDs

The genetic basis of schizophrenia is still largely unknown. Recent evidence suggests that a microRNA (miRNA), miR-137 may be involved. The first large schizophrenia genome wide association (GWAS) study, published in 2011, identified a variant within the host gene of this miRNA (MIR-137) as the top association. Since then, further evidence for the potential influence of this miRNA within the disorder has accumulated. These studies used a variety of methods from GWAS to neuroimaging. However, few studies have evaluated the mechanism for the association of the MIR-137 variant, nor how alterations in the miRNA may have downstream effects on its …

Investigation Into The Early Events Of Epithelial Wound Healing And Hpv16 Infection, Michael P. Kivitz

Biomedical Sciences ETDs

HPV16 infection evidently occurs within wounded epithelial tissue, but the cellular and molecular events that culminate in infection establishment remain poorly understood. While HPV is exposed to a multitude of cells in the wound environment, only hyperproliferative keratinocytes are believed to support productive infection. Keratinocytes acquire mobility during wound repair by undergoing prominent phenotypic alterations through an epithelial-to-mesenchymal transition (EMT). In this study, cell- and tissue-based models were employed to characterize HPV infection during epithelial wound healing, using both physical injury and growth factor treatment to induce keratinocyte migration. In a tissue-based model of wounding and infection using NIKS-derived organotypic …

In Vivo Dosimetry Using Plastic Scintillation Detectors For External Beam Radiation Therapy, Landon S. Wootton

Dissertations and Theses (Open Access)

In vivo dosimetry, the direct measurement of dose delivered to patients during radiation therapy, has significant potential in ensuring safe and effective treatment in radiation therapy. It can serve as point-of-delivery, patient specific quality assurance and direct verification of treatment. Despite evidence that in vivo dosimetry can detect errors in patient treatment that would otherwise go undetected, it is not commonly practiced. This is due in part to a lack of available detectors ideally suited to perform in vivo dosimetry. Plastic scintillation detectors (PSDs) possess a number of dosimetric characteristics advantageous for in vivo dosimetry including water equivalence, real-time capability, …

Novel Posttranslational Modification In Lkb1 Activation And Function, Szu-Wei Lee

Dissertations and Theses (Open Access)

Cancer cells display dramatic alterations in cellular metabolism to meet their needs of increased growth and proliferation. In the last decade, cancer research has brought these pathways into focus, and one emerging issue that has come to attention is that many oncogenes and tumor-suppressors are intimately linked to metabolic regulation (Jones and Thompson, 2009). One of the key tumor-suppressors involved in metabolism is Liver Kinase B1 (LKB1). LKB1 is the major upstream kinase of the evolutionarily conserved metabolic sensor—AMP-activated protein kinase (AMPK). Activation of the LKB1/AMPK pathway provides a survival advantage for cells under energy stress. LKB1 forms a heterotrimeric …

Lady Gaga: Performer, Persona, And Political Advocate, Cassidy Burns

Communication Studies

No abstract provided.

Metal Assisted Nanowire Growth For Silicon Nanowire/Amorphous Silicon Composite Solar Cell, Asmaa Ali Sadoon

Graduate Theses and Dissertations

Solar cells are photovoltaic devices that convert the energy of light to electricity by the photovoltaic effect. Crystalline silicon-based solar cells are the most dominant solar cells in the market today due to the high efficiency and relatively low cost. However, the cost of such solar cell is still high due to the large amount of material that is consumed in fabricating such a device. Polycrystalline/amorphous thin films and nanomaterial technologies have emerged to reduce the high cost of c-Si based solar cells and increase the efficiency. In this research, we combined these two technologies to propose and fabricate silicon …

The Mechanism Of Lhcp Insertion Into Thylakoid Membranes, Larae Brown

Graduate Theses and Dissertations

The light harvesting chlorophyll a/b-binding proteins (LHCPs) are the most abundant membrane proteins. LHCP is a nuclear encoded protein which is targeted to the thylakoid membranes by chloroplast signal recognition particles (cpSRP). Insertion into thylakoid membranes is facilitated by the cpSRP receptor cpFtsY and the Alb3 translocase. Work here focused on understanding the molecular events of LHCP insertion into the thylakoid membranes. Specifically, we sought to develop a tool to detect the insertion of the lumen-localized loop of LHCP into thylakoid membranes, which relies on cleavage of the loop by a thylakoid lumen processing protease. We also sought to understand …

Teacher Internship Report- Ceres High School, Michael L. Patterson

Agricultural Education: Graduate Internship Reports

This internship/project report includes validation documents required in meeting the quality criteria for secondary-level programs of instruction in agriculture. The documents are concurrently used for the Agriculture Incentive Grant review process at Ceres High School conducted by representatives of the California Department of Education. The internship included the development of a comprehensive program plan for Ceres High School. The plan includes information to receive state/local funding, outline the goals and objectives of the program, along with an overview of Ceres High School, the agriculture program and community.

Pattern And Outcome Of Epilepsy At Department Of Neurology At Cmc Teaching Hospital Larkana, Alam Ibrahim Siddiqui, Badaruddin Junejo, Lal Chander Dhingra, Anila Mumtaz

Pakistan Journal of Neurological Sciences (PJNS)

Epilepsy is third most common chronic neurological disease. Mortality is 2-3% more common in epilepsy patients than in general population. World wide survey have shown that epilepsy responds to treatment in about 70 % of epileptic patients and three fourth of the affected people do not get the treatment they need. So objective of our study was to know the outcome and pattern of epilepsy at Department of Neurology CMC teaching hospital Larkana ,so that in next step we could know which factors could reduce the morbitity and mortality due to epilepsy hence could prevent complications due to epilepsy. Total …

A Clinical Approach To Disorders Of Speech, Apoorva Pauranik

Pakistan Journal of Neurological Sciences (PJNS)

Disorders of speech and communication, including Aphasia (mainly post stroke) are a major community health burden in terms of DALY (Disability Adjusted Life Years). Unfortunately they are relatively neglected with huge treatment gap. Traditionally aphasia related lesion sites have been grouped with reference to Rolandic & Sylvian fissures. However the theoretical models of language and speech organization in brain have undergone major conceptual shifts due to advances in cognitive neuropsychology, linguistics and functional neuro-imaging. Much more widely distributed overlapping neural networks are understood to be actively involved in various communication activities. The notion of speech centers or areas is somewhat …

A Portable Impedance Biosensing System Based On A Laptop With Labview For Rapid Detection Of Avian Influenza Virus, Yixiang Wang

Graduate Theses and Dissertations

Avian Influenza Virus (AIV) H5N1 is a highly pathogenic virus found not only in birds but also in human. Rapid and sensitive detection method is needed to help prevent the spread of AIV H5N1. In this study, a portable impedance biosensing system based on a laptop with LabVIEW software was developed for detection of AIV H5N1. First, a virtual instrument was programmed with LabVIEW software to form a platform for impedance measurement, data processing and control. The audio card of a laptop was used as a function generator while a data acquisition card was used with the signal channels for …

Control Of Agrilus Ruficollis (Coleoptera: Buprestidae) With Insecticides And Identifying Visual Attractants For Use In A Monitoring Trap, Soo-Hoon Kim

Graduate Theses and Dissertations

The rednecked cane borer, Agrilus ruficollis (F.), is a pest of cultivated and wild blackberries in the Midwestern and Eastern parts of the United States. Feeding, mating, egg laying and development of A. ruficollis from larvae to adult only occurs on primocane, the first year vegetative growth stage of blackberries, and not on the second year fruiting stage called floricanes that die after fruiting. Damage from this pest is caused by the larva girdling the primocane and tunneling in the pith, causing the formation of a gall. Gall formation on the primocane increases the chance of winter injury and can …

Functional Genomics And Microbiome Profiling Of The Asian Longhorned Beetle (Anoplophora Glabripennis) Reveal Insights Into The Digestive Physiology And Nutritional Ecology Of Wood Feeding Beetles, Erin D. Scully, Scott M. Geib, John E. Carlson, Ming Tien, Duane Mckenna, Kelli Hoover

Department of Agronomy and Horticulture: Faculty Publications

Background: Wood-feeding beetles harbor an ecologically rich and taxonomically diverse assemblage of gut microbes that appear to promote survival in woody tissue, which is devoid of nitrogen and essential nutrients. Nevertheless, the contributions of these apparent symbionts to digestive physiology and nutritional ecology remain uncharacterized in most beetle lineages.

Results: Through parallel transcriptome profiling of beetle- and microbial- derived mRNAs, we demonstrate that the midgut microbiome of the Asian longhorned beetle (Anoplophora glabripennis), a member of the beetle family Cerambycidae, is enriched in biosynthetic pathways for the synthesis of essential amino acids, vitamins, and sterols. Consequently, the midgut …

Reconciliation Ecology: A New Paradigm For Advancing Creation Care, Dave P. Warners, Michael Ryskamp, Randall Van Dragt

University Faculty Publications and Creative Works

Current global environmental challenges—species loss, overconsumption, climate change, and others—have not been countered in the faith community with a response worthy of their signifi cance. While the prevailing faith-based creation-care paradigm, environmental stewardship, has been invaluable in moving us beyond the utilitarian notion of “dominion,” the stewardship concept does not suffi ciently emphasize our embedded, dependent relationship with the creation. To better represent our creationcare responsibilities, we propose a new paradigm based on a model of servanthood and informed by the concept of reconciliation ecology, which focuses on mending broken relationships between human beings and nonhuman creation. Drawing from the …

Effects Of Feeding Distillers Grains Throughout A Yearling Heifer Beef Production System On Meat Quality Attributes And Effects Of Omnigen-Af With Ractopamine Hydrochloride On Animal Performance And Beef Carcass Characteristics Of Feedlot Steers, Kelby M. Sudbeck

Department of Animal Science: Dissertations, Theses, and Student Research

Heifers (n = 229; 225 kg ± 2) were used in a 2 x 2 x 2 factorial to determine the effects of longterm exposure to corn distillers grains plus solubles (DGS) on meat quality characteristics. Factors included supplementing 0.91 kg (LW) or 2.3 kg (HW) modified DGS (MDGS) while grazing corn stalks; 0.6% BW dry DGS (SS) daily or none (NS) during summer grazing; and finishing diet containing 40% wet corn gluten feed (CGF) or 40% MDGS (DGF) on a DM basis. An interaction was observed within CGF for discoloration, with SS increasing discoloration 30%; but no differences between …

Metadata Determination For A Cadaveric Collection, Shamsi Rebecca Berry

Biomedical Sciences ETDs

The number, size and complexity of research databases continue to grow unabated. Yet, despite significant advances in information technology, scientists continue to struggle with 'data wrangling' or issues of finding, sharing, and reusing data, often for unanticipated future purposes. Most research databases are designed ad hoc, by native investigators for specific research functions and immediate needs with little to no input from database designers, informaticians, or other subject matter experts. Little thought is usually given to the implications of future data retrieval, sharing and reuse. When the needs of future investigators or research requirements change, the original design of the …

The Greenback, The Humpback, And The Silverback: How A Third Wave Of Federal Water Policy Could Benefit The West, Reed D. Benson

Faculty Scholarship

Proposing any major new federal initiative regarding water in the western United States might seem preposterous, given conventional wisdom and entrenched positions on state control of water resources. But there is a strong rationale, and a growing imperative, for a new federal water .policy for the West. Many river basins face serious problems as limited water supplies are over-allocated, demands continue to increase, and climate change promises to exacerbate the West's perennial problems of scarcity and variability. Solutions to such problems are likely to be expensive and will need to address national interests as well as state and local concerns. …