Digital Commons Network^™

Alkaloid Production By Hairy Root Cultures, Bo Zhao

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

In the present research, nicotine alkaloid production by Nicotiana tabacum (tobacco) hairy roots and tropane alkaloid production by Hyoscyamus niger hairy roots were investigated. The first objective of this research was to improve the oxygen mass transfer in hairy root cultures with microbubbles. Oxygen was shown as a critical nutrient for the growth of tobacco and H. niger hairy roots. In a 1-liter fermentor, microbubble dispersion improved the oxygen mass transfer, tobacco hairy root growth, and nicotine production in the medium. In a novel ground-joint column bioreactor, microbubbles enhanced the oxygen mass transfer and the growth of H. niger hairy …

Landscape Evolution Of The Needles Fault Zone, Utah, Investigated Through Chronostratigraphic And Terrain Analyses, Faye L. Geiger

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Arcing eastward from the deep gorge of Cataract Canyon on the Colorado River is a series of aligned valleys (graben) and ridges (horst). This unusual landscape has formed as subsurface salt deforms toward the river and dissolves away, causing the overlying rocks to fault, slide, and subside. Geologists have long been interested in this actively evolving area they call the Needles fault zone, because understanding its mechanics and origin may shed light on how faults work in general and similar, yet inaccessible places like offshore rift zones or even the surface of the Moon. Despite this interest, the timing and …

Metabolic Modeling Of Spider Silk Production In E. Coli, Sarah Allred

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Spider silk has the potential to be a useful biomaterial due to its high tensile strength and elasticity. It is also biocompatible and biodegradable, making it useful for wound dressings and sutures, tissue and bone scaffolds, vessels for drug delivery, and ligament and tendon replacements. In some studies where spider silk has been used to grow cells, the silk has promoted more cell growth than the control. However, it is difficult to obtain the high volume of silk needed for these undertakings on a large scale. Spiders are territorial and cannibalistic, so they cannot be easily farmed. Therefore, spider silk …

Effect Of Poultry Litter Biochar On Saccharomyces Cerevisiae Growth And Ethanol Production From Steam-Exploded Poplar And Corn Stover, Oumou Diallo

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The use of ethanol produced from lignocellulosic biomass for transportation fuel offers solutions in reducing environmental emission and the use of non-renewable fuels. However, lignocellulosic ethanol production is still hampered by economic and technical obstacles. For instance, the inhibitory effect of toxic compounds produced during biomass pretreatment was reported to inhibit the fermenting microorganisms, hence there was a decrease in ethanol yield and productivity. Thus, there is a need to improve the bioconversion of lignocellulosic biomass to ethanol in order to promote its commercialization. The research reported here investigated the use of poultry litter biochar to improve the ethanol production …

Information And Hardness Quantification Of Graphs: A Computational Study, Brent Dutson

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

New techniques to measure the information contained within a network of interconnected nodes (such as links between computers in the Internet) have recently been developed. This work studies the relationship between the computer time needed to solve a common network problem and the information contained within the given network.

Synthesizing Research And Education: Ecology And Genetics Of Independent Fern Gametophytes And Teaching Science Inquiry And Content Through Simulations, Aaron M. Duffy

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The mission statements of Utah State University and the Department of Biology, as well as the requirements of funding agencies like the National Science Foundation encourage an integration of teaching and research. I have attempted to achieve that in my dissertation work by using tools I originally created to support and inform my biological research projects to teach science content and inquiry to middle school and undergraduate students.

Chapter 2 of this dissertation reports the results of surveys for Hymenophyllum wrightii, a fern with independent gametophyte populations in the Pacific Northwest, which improved our understanding of the range, distribution, …

Ghrelin Concentrations In Milk And Plasma Of Dairy Cows During Early Lactation, Sameer M. Alhojaily

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Ghrelin is a hormone produced mainly by the cells lining the gastric mucosa. Ghrelin was first extracted from human and rat stomachs, and identified as an endogenous stimulator of growth hormone release. Ghrelin is synthesized and produced in several tissues, but the gastric mucosa remains the major source of circulating ghrelin. Besides growth hormone release, ghrelin stimulates appetite and plays some major roles in different organs. In several studies, ghrelin was described as a hormone with multiple functions and diverse biological actions. Ghrelin exists in two major forms, active ghrelin and inactive ghrelin, and only the active from binds to …

Self-Reported Psychopathology Correlates Of Homeless Youth In Utah, Kimberlee Taylor

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Homelessness among unaccompanied youth is a unique, yet pervasive, social problem. Youth often become homeless through three central pathways: conflict with family, involvement in the foster system, and involvement in juvenile justice systems. As youth experience homelessness during important developmental period(s), vulnerability to mental illness may occur if not already present. The present study examined the type and prevalence of mental illness. Characteristics of homelessness, health and mental health service utilization, and pathways to homelessness were examined in relation to the occurrence of mental illness. Findings indicated that a variety of characteristics are associated with mental illness. Mental health service …

Impact Of Organic Matter Composition From Urban Streams And Storm Water On Oxygen Consumption In The Jordan River, Jacob Matt Richardson

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The water quality of the Jordan River has been the subject of a Total Maximum Daily Load study conducted under the direction of the Utah Department of Environmental Quality's Water Quality Division (DWQ). They have determined the oxygen impairment issues in the river are most likely tied to the amount of organic material entering the river from various sources.

The focus of the study conducted by Jacob Richardson was organic material that enters the Salt Lake City storm drain system, and is eventually released into the Jordan River. He found that leaves, grass, and wood particles that enter the storm …

Effects Of Processing And Packaging Modifications On The Quality And Shelf Life In Meats, Abdulla Khan

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Shelf life of foods, mainly meat and meat products, is affected by its physical and chemical properties like color, pH, water holding capacity etc. In developed countries
food losses occur at production, retail and consumer levels with meat commodities accounting for 41% of the total loss in US during 2008. These losses are because of
spoilage due to inappropriate packaging, improper storage conditions, food wastage, and lack of consumer awareness. By focusing on shelf life and quality issues at the production level, we can overcome some of the major problems faced by the food manufacturers.

Active packaging is an innovative …

Specific Learning Disabilities: Beliefs About The Construct, Identification Methods, And Job Satisfaction Among Practicing School Psychologists, Joseph M. Cottrell

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Students with specific learning disabilities (SLDs) account for approximately 40% of all students receiving special education services. Debate among professionals regarding the causes of SLDs and the most appropriate methods used to identify SLDs persists. This debate may be related to the increase in prevalence of SLDs since the implementation of special education law in 1975. There are three prominent theories regarding the cause of SLDs: (a) environmental theory, (b) biological theory, and (c) interactional theory. The Individuals with Disabilities Education Act (IDEA) allows school districts to implement the following SLD identification procedures: (a) the IQ-Achievement discrepancy method, (b) response-to-intervention …

Effects Of Dietary Polyunsaturated Fatty Acids On Colorectal Cancer And The Development Of The Total Western Diet-2, Sara Kellen

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The Western diet is commonly consumed by industrialized societies and characterized by an increased consumption of vegetable oils rich in omega-6 (n-6) fatty acids. This results in a higher ratio of omega-6 to omega-3 (n-3) fatty acids in the diet. Omega-6 polyunsaturated fatty acids (PUFA) are believed to induce a pro-inflammatory response in the body. Therefore, this change in PUFA concentration and/or ratio of n-6:n-3 in the Western diet may contribute to colorectal cancer (CRC) risk. Five identical diets, varying only in PUFA concentration and n-6:n-3 ratio, were fed to mice dosed with a carcinogen and an inflammatory accent (AOM+DSS). …

Distribution Of Heavy Metals From Flue Gas In Algal Bioreactor, Katerine Napan

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Algae are microscopic organisms with a great potential to produce biomass and lipids at productivities several times higher than terrestrial crops. To grow, these organisms consume carbon dioxide (CO₂), a greenhouse gas. This gas, emitted primarily by power plants after coal burning, can be effectively used for algae production, thus resulting in CO₂ remediation and biomass beneficial utilization as feedstuff, industrial filler and biodiesel feedstock. However, since coal is a fuel mined from the earth’s crust, it contains heavy metals that are released during coal burning and inevitably enter the algal cultivation system, contaminating the water were …

Investigations Of Cho 1-15 And Silk Gland Cell Line Development, Susan Kathleen Robinson

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The BioProcessing Demonstration and Training Laboratory was established with a collaboration between Utah State University and Thermo Fisher-Scientific, Inc. This lab was developed into a fully functioning tissue culture facility. Demonstration of tissue culture procedures were necessary for the lab to be industry-fully qualified. The CHO 1-15 cell line protocols were optimized by establishing conditions for reproducibility in shaker flasks and bioreactors (2 to 250 L capacity). CHO 1-15 is the cell line of choice for protein production in the bio-manufacturing industry. Oxidative stress is a problem in the industry because it can cause a decrease in protein production. Mesobiliverdin …

Macroinvertebrate-Driven Nutrient Recycling In Four Large Rivers, Matt A. Schroer

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The cycling of nutrients is a fundamental process in streams and rivers, and scientists are increasingly recognizing the importance of animal communities to nutrient dynamics in these ecosystems. Despite growing evidence that animal excretion (i.e. urine) can supply limiting nutrients to primary producers in small streams, the importance of excretion is uncertain in large rivers. Accordingly, I used three estimation approaches based on past and new excretion rate data to determine nitrogen (N) and phosphorus (P) excretion inputs from insect communities in four large rivers (discharge > 10 cubic meters per second) in North America, and I compared these rates to …

The Ecosystem Role Of Fishes In Lotic Environments, Christopher C. Wheeler

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

It is important for humans to understand how ecosystems work because we depend on them for a variety of products and services. For example, rivers and streams provide fisheries, improved water quality, and recreational opportunities to many individuals. In rivers, interactions among fishes, other stream plants and animals, and the physical river environment can influence continued provision of these valuable services. However, the role played by many freshwater fishes in the provision of these services remains unknown. Additionally, it is important to identify different factors that affect the outcome of interactions involving riverine fishes. To address these issues, I evaluated …

Adolescent Self-Described Volume Of Texting: Discovering Relationships With Psychosocial Development And Interpersonal Relationships, Tessa Cutler

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Researchers explored the relationship among adolescent self-reported amounts of texting and self-esteem, self-construal, autonomy, and attachment. Data were collected from a high school in an urban area in the Mountain West. Participants included 180 students (53% female). Participants were asked to self-describe their volume of texting as high, medium, or low. Participants were also asked to complete the following scales: Rosenberg Self-Esteem Scale, the Self-Construal Scale, the Case Inventory, The Adolescent Autonomy Questionnaire, and The Modified Inventory of Parent and Peer Attachment.

It is suggested that text messaging is more strongly related to self-esteem when texting is placed as the …

Barriers To Curricular Change In General Education Mathematics At A Large Public Institution, Marcus Jorgensen

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

This qualitative study looked for barriers to curricular change in general education mathematics at a large public university (LPU) in the Western United States. The literature showed that a number of national organizations dealing in math education have recommended alternatives to the traditional algebra-intensive curriculum. LPU still relies predominantly on traditional College Algebra as its quantitative literacy (QL) course. With such an algebra-heavy emphasis, students may be missing more relevant and useful mathematics. In addition, the College Algebra course has a low success rate, which becomes a barrier to student retention and graduation. Interviews were conducted with 14 participants who …

Systematics And Behavioral Evolution Of Spider Wasps (Hymenoptera: Pompilidae), Cecilia Waichert Monteiro

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Spider wasps form a diverse and widespread group of stinging wasps. Although all Pompilidae have similar life history characteristics, there is considerable variation in nesting behavior modes and, thus, this family could be useful for learning about the evolution of nesting behavior in insects. The nesting behavior of many species is well known, the family is monophyletic and easily recognized, and certain species have some degree of pre-sociality, i.e., communal nesting. All these factors suggest that the Pompilidae are an important model group for understanding mechanisms and patterns of behavioral evolution.

Pompilidae, however, are rarely studied and their research potential …

Effects Of Gangliosides On The Activity Of The Plasma Membrane Ca2+-Atpase, Lei Jiang, Misty D. Bechtel, Jennifer L. Bean, Robert Winefield, Todd D. Williams, Asma Zaidi, Elias K. Michaelis, Mary L. Michaelis

Faculty and Staff Publications

Control of intracellular calcium concentrations ([Ca(2+)]i) is essential for neuronal function, and the plasma membrane Ca(2+)-ATPase (PMCA) is crucial for the maintenance of low [Ca(2+)]i. We previously reported on loss of PMCA activity in brain synaptic membranes during aging. Gangliosides are known to modulate Ca(2+) homeostasis and signal transduction in neurons. In the present study, we observed age-related changes in the ganglioside composition of synaptic plasma membranes. This led us to hypothesize that alterations in ganglioside species might contribute to the age-associated loss of PMCA activity. To probe the relationship between changes in endogenous ganglioside content or composition and PMCA …

Pop2: A Potential Regulator Of Hmt1-Catalyzed Arginine Methylation In Yeast, Celeste Excell

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Protein arginine methylation is an important post-translational modification that is vital in regulating various cellular processes such as gene transcription, cell signaling, and RNA processing. Protein arginine methyltransferases (PRMTs) are responsible for performing this important modification. PRMT1 (protein arginine methyltransferase 1) and Hmt1 (hnRNP methyltransferase 1) are the predominant PRMTs in humans and yeast, respectively. Despite growing momentum in this field, relatively little is understood about PRMT regulation. Further work discovering how PRMTs are regulated will greatly advance our understanding of diseases where PRMTs have been implicated, such as heart disease, viral pathogenesis, and cancer.

It has been discovered that …

Ecomorphological And Genetic Investigations Into The Utah Lake, Ut Sucker Complex With Comparisons To The Jackson Lake, Wy Sucker Complex, David D. Cole

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Natural selection within the sucker family of fishes has produced populations including typical benthic (bottom-feeding) suckers (Catostomus) and lakesuckers (Chasmistes), mid-water plankton eaters, in several large western North American lakes. Suckers of intermediate morphology (shape) exist in a continuum of head, mouth, and body characteristics between these two extremes. All current lakesuckers are listed Endangered, and population declines have been attributed in part to hybridization with their Catostomus neighbors.

Chapter 2 describes the investigation of the relationship between morphology and genetics of June sucker, a lakesucker, and Utah sucker, a benthic sucker, in Utah Lake, Utah. …

The Mental Health Disparity Among Nonheterosexuals: Risk, Resiliency, And New Perspectives To Consider In The Context Of Mormonism, Katherine Ann Crowell

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Nonheterosexuals disproportionately experience mental illness when compared with heterosexuals. Although it has been well established that the apparent mental health disparity among sexually diverse populations is almost exclusively derived from minority stress (i.e., the excess stress associated with culturally maintained sexual stigma), our understanding of how specific aspects of minority stress lead to specific psychological syndromes (e.g., depression) remains limited. On the other hand, in attempts to destigmatize individuals who do not identify as heterosexual, researchers have increasingly begun to shift the focus of their work towards understanding the specific characteristics or experiences that facilitate individuals’ capacity to adapt and …

Parental Perceptions Of The Influence Of Digital Media And Technology On Children's Reading Habits At Home, Kurt W. Johnson

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

This study explored how parents from six participating families in Northern Utah felt about the influence of technology and media on their children’s reading at home. Each family was interviewed about their feelings, filled out a survey about the amount of technology devices in the home, and took photographs of the areas in the home where their children read or used technology. Additionally, each family kept a journal recording the technology and reading activities their children participated in over a 1-week period

Parents talked about how their childhood experiences influenced them to create rules for technology and as well as …

Excimer-Monomer Switching Molecular Beacon: The Study On Synthetic Cryptosporidium Dna Detection, Thermodynamics, And Magnesium Effects, Michael L. Davis

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The purpose of this study is to quantify and determine the binding of a molecular DNA probe or molecular beacon used in the detection of a known waterborne pathogen Cryptosporidium parvum. The objectives of this study are to determine the stability, sensitivity, and selectivity of the molecular beacon in detecting synthesized Cryptosporidium DNA sequences. The designed probe is based on a two-fluorophore system that is different than similar molecular beacons that utilize a fluorophore and quencher detection method. A comparative study between the two probes was also performed to demonstrate enhanced selectivity of the fluorophore based molecular beacon. Magnesium …

Three Essays On The Economics Of Controlling Invasive Species, Yanxu Liu

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Invasive species have caused notable economic damages in agriculture, fisheries, forestry, and other industries over the past several decades. Invasive species control must therefore be designed to prevent the both the introduction and spread of invasive species. This dissertation examines the efficiency and efficacy of tariffs and inspections as a joint control mechanism at a home (i.e., importing) country's border. I find that a traditional tariff can be optimal in the short run when the invasive species level is directly related to a foreign (i.e., exporting) country's shipment size. However, in the long run a traditional tariff results in a …

Quantum Mechanical Study Of Weak Molecular Interactions, Upendra Adhikari

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Molecular interactions play key role in the existence of biomolecules like proteins and nucleic acids, and various materials. Molecular interactions are weak forces that hold different molecules or different fragments of the same molecule together, and are often referred to as noncovalent interactions. Due to the complexity in biomolecules, these interactions are still poorly understood. This dissertation presents results from quantum mechanical simulations of various types of noncovalent interactions, which are extremely important for the structure and functions of biomolecules and materials.

A new sort of noncovalent interaction is identified. This new sort of interaction originates from a direct interaction …

Nonlinear Weir Hydraulics, Mitchell R. Dabling

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

A hydraulically undersized control structure (i.e., an emergency dam spillway) could result in water overtopping a dam or riverbanks. To increase hydraulic capacity and reduce flooding risk, nonlinear weirs are being used to replace undersized linear weirs during control structure rehabilitation. The complex geometry of a nonlinear weir creates an infinite number of designs and three-dimensional flow patterns. This study investigates four subjects to further knowledge on two types of nonlinear weir, the piano key and labyrinth.

Weir submergence is a condition when the downstream water level of a weir exceeds the weir crest elevation, and can influence the head-discharge …

An Evaluation Of The Food Web Dynamics And Predator Prey Interactions In Scofield Reservoir, Lisa K. Winters

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Reservoirs are artificial, dynamic, and highly manipulated systems, where the appearance of either intentionally or unintentionally introduced species may disrupt interactions within an already complex food web. In some situations, a top predator fish may be stocked as a biological control agent, if these fish-eating predators monopolize on the nuisance and unwelcome prey. Scofield Reservoir, Utah has historically been an extremely popular blue-ribbon fishery. However, a recent decrease in rainbow trout catch and increase in the minnow, Utah chub, have made it difficult to find a balance between providing the public with a trophy sport fishery and maintaining an ecologically …

Activated Carbon Decreases Invasive Plant Growth By Mediating Plant-Microbe Interactions, Nicole E. Nolan

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

To restore lands invaded by dense, non-native vegetation, it may be necessary to develop targeted restoration tools than can remove the mechanism used by these non-native species as a competitive advantage. Activated carbon (AC) is one such tool, with the ability to disrupt the mechanisms of plant to plant communication (allelopathy) and positive plant to microbe communication commonly used by non-native species. Previous studies have shown the success of high concentrations, 1000g/m², of AC in native plant community restoration on a small scale. Here, our goals are twofold: first, to test AC effectiveness in restoring desirable plant communities …