Digital Commons Network^™

Subcellular Metabolite And Lipid Analysis Of Xenopus Laevis Eggs By Laesi Mass Spectrometry, Bindesh Shrestha, Prabhakar Sripadi, Brent R. Reschke, Holly D. Henderson, Matthew J. Powell, Sally Ann Moody, Akos Vertes

Anatomy and Regenerative Biology Faculty Publications

Xenopus laevis eggs are used as a biological model system for studying fertilization and early embryonic development in vertebrates. Most methods used for their molecular analysis require elaborate sample preparation including separate protocols for the water soluble and lipid components. In this study, laser ablation electrospray ionization (LAESI), an ambient ionization technique, was used for direct mass spectrometric analysis of X. laevis eggs and early stage embryos up to five cleavage cycles. Single unfertilized and fertilized eggs, their animal and vegetal poles, and embryos through the 32-cell stage were analyzed. Fifty two small metabolite ions, including glutathione, GABA and amino …

College Co-Hosts D.C. Policy Forum; Alum On Panel, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Film Tourism: The Pre-Production Perspective. A Case Study Of Visit Somerset And The Hollywood Story Of Glastonbury., Na Semley, G Busby

Plymouth Business School

Film tourism has been researched now for many years and the consequences of post-production are clear. However, there has been little opportunity to explore the perceptions of filming, pre-production, until now. Using a case study approach to the making of one particular Hollywood film on a rural location, the paper focuses on evaluating the business of film tourism and establishing the perceived impacts of film tourism from advanced practitioners and local residents, respectively. Two stages of data collection were adopted during pre-production: elite interviews and focus groups. The findings reveal that the role of each practitioner shapes their level of …

How Has Poland Done The Eu Cohesion Policy Lesson? The Case Of Polish Regional Development System Modification, Izabela Siekierska-Rosiak

European Management Studies

In the beginning of the last decade of XX century regional policy in Poland constituted a small part of all the actions under the public policy. In the second decade of XXI century, regional policy become the main policy realizing the development policy in Poland. During this twenty years the system of regional policy has changed a lot. The changes were mainly caused by transformation of polish economy from the central planning economy to market economy as well as the accession to European Union. The research concentrates on changes of the system of regional policy. The article starts with presentation …

Kaczmarz Iterative Projection And Nonuniform Sampling With Complexity Estimates, Tim Wallace, Ali Safak Sekmen

Computer Science Faculty Research

Kaczmarz’s alternating projection method has been widely used for solving mostly over-determined linear system of equations Ax = b in various fields of engineering, medical imaging, and computational science. Because of its simple iterative nature with light computation, this method was successfully applied in computerized tomography. Since tomography generates a matrix A with highly coherent rows, randomized Kaczmarz algorithm is expected to provide faster convergence as it picks a row for each iteration at random, based on a certain probability distribution. Since Kaczmarz’s method is a subspace projection method, the convergence rate for simple Kaczmarz algorithm was developed in …

Comment On The Cfpb's Policy On No-Action Letters, Jeffrey Lederman, K. Sabeel Rahman, David J. Reiss

Cornell Law Faculty Working Papers

A No-Action Letter reduces uncertainty for Businesses that are attempting to bring legitimate and innovative Products to market. Businesses will rely on these letters and shape their behavior based on them.

At the same time, issuing a No-Action Letter risks encouraging the development of abusive Products if granted with insufficient analysis. Perhaps as importantly, but not as obviously, failing to issue a No-Action Letter at all can also damage consumers by failing to incentivize the development of innovative Products that help consumers. The goal of the Policy should be to balance the promotion of innovation with consumer protection.

Honors Recital Presentation, David Rutter

Honors Projects

The purpose of this project was rooted in the belief that the reception of a piece of music can be altered or enhanced when the audience is given a compelling historical or cultural background of each composition. With sometimes hundreds of years between the audience members and the composers, to deliver an emotionally stirring and relevant performance to a modern audience is an incredible feat. In the spirit of making my senior violin recital more accessible and entertaining to my own audience, I devoted my Honors project to gathering information on the philosophies, personalities, successes and tragedies of each of …

Cd151-Α3Β1 Integrin Complexes Suppress Ovarian Tumor Growth By Repressing Slug-Mediated Emt And Canonical Wnt Signaling, Lauren A. Baldwin, John T. Hoff, Jason Lefringhouse, Michael Zhang, Changhe Jia, Zeyi Liu, Sonia Erfani, Hongyan Jin, Mei Xu, Qing-Bai She, John R. Van Nagell Jr., Chi Wang, Li Chen, Rina Plattner, David M. Kaetzel, Jia Luo, Michael Lu, Dava West, Chunming Liu, Fred R. Ueland, Ronny Drapkin, Binhua P. Zhou, Xiuwei H. Yang

Pharmacology and Nutritional Sciences Faculty Publications

Human ovarian cancer is diagnosed in the late, metastatic stages but the underlying mechanisms remain poorly understood. We report a surprising functional link between CD151-α3β1 integrin complexes and the malignancy of serous-type ovarian cancer. Analyses of clinical specimens indicate that CD151 expression is significantly reduced or diminished in 90% of metastatic lesions, while it remains detectable in 58% of primary tumors. These observations suggest a putative tumor-suppressing role of CD151 in ovarian cancer. Indeed, our analyses show that knocking down CD151 or α3 integrin enhances tumor cell proliferation, growth and ascites production in nude mice. These changes are accompanied by …

Scientizing Culpability: The Implications Of Hall V. Florida And The Possibility Of A “Scientific Stare Decisis”, Christopher Slobogin

William & Mary Bill of Rights Journal

The Supreme Court’s decision in Hall v. Florida held that “clinical definitions” control the meaning of intellectual disability in the death penalty context. In other words, Hall “scientized” the definition of a legal concept. This Article discusses the implications of this unprecedented move. It also introduces the idea of scientific stare decisis—a requirement that groups that are scientifically alike be treated similarly for culpability purposes—as a means of implementing the scientization process.

Tech Edge Use Of New Literacies In Elementary Classrooms Today: A Partnership To Enhance Student Learning Through Teacher Preparation And Professional Development, Qizhen Deng, Laurie A Friedrich, Guy Trainin

Research and Evaluation in Education, Technology, Art, and Design

Tech EDGE has been able to capitalize on past funding to create significant impact across multiple public and private schools. Support from UNL’s resources have enabled us to operate far beyond the official end date so we can keep building on our successes and the energy the project provided for school change. We have trained hundreds of practicing and new teachers to integrate technology and while the work is not done it did a lot to boost the capacity in all the participating districts and teacher education programs. We would like to thank the Post Secondary Commission for the generous …

Neutral Density Behavior From 45-90 Km Based On Rayleigh Lidar Observations Above Usu, David Barton

Physics Capstone Projects

There are over 900 nights of observations taken by the Rayleigh lidar above Utah State University from 1993 to 2004. The data have been reduced to give absolute temperatures and relative densities in the mesosphere, from 45-90 km (Herron, 2004, 2007). From the 11 years of relative density data an 11-year climatology of mesospheric densities above Logan, Utah has been created. From this climatology I have been able to normalize the 11 years of density data to the following models: the MSISe00 empirical model, the CPC (Climate Prediction Center) reanalysis model, the ERA Interim reanalysis model, and the NASA MERRA …

Homeland Self Storage Management Llc Order Deferring Defendants' Motion For Protective Order And Appointment Of Special Master For Financial Discovery, John J. Goger

Superior Court of Fulton County: Metro Atlanta Business Case Division Opinions

No abstract provided.

Daily Eastern News: December 15, 2014, Eastern Illinois University

December

No abstract provided.

Michael Lehtonen V. Governor Of The Virgin Islands

2014 Decisions

USDC for the District Court of the Virgin Islands

Mathematics And Statistics Academic Program Review, 2014, College Of Science And Mathematics, Wright State University

Academic Program Review Reports - All

This 23 page report reviews several programs from Wright State University's Department of Mathematics and Statistics, specifically looking at the time from Fall 2009 to Fall 2014. Programs Reviewed: Applied Mathematics Mathematics (BA/BS, MS, and minor) Applied Statistics Statistics (BS and minor)

(Un)Wrapping Felix Gonzalez-Torres: The Relational Power And Contagious Wonderment Of Candy And Other Things, Brooke Clark

Honors Theses

Huddled in the corner of the cold, sterile floor of The Art Institute of Chicago, Felix Gonzalez-Torres's Untitled (Portrait of Ross in L.A.), 1991 is a mound of individually wrapped, multihued candy that can be possessed, consumed, and rearranged by the audience (artic.edu). The parenthetical remark within the title suggests the portrait is that of a human. In fact, Ross was the artist's lover, who died of AIDS in the year 1991. The candy spill memorializes Ross at his healthy weight of one hundred seventy-five pounds. Even as Ross's body is implicated in the candy, the candies themselves contain and …

Compositional Traits In Sorghum Bicolor Characterized By Transcriptome, Ionome And Genome-Wide Association Analysis, Nadia Shakoor

Theses and Dissertations

To address the challenge of global mineral malnutrition, current biofortification research in crop plants aims to improve mineral concentration and micronutrient bioavailablity via genetic and traditional breeding methods. Many staple food crops are also used as biofuels, and the chemical and mineral composition of these energy crops directly affect biomass quality and subsequent energy output. Identification of genes and QTL that impact mineral and compositional traits in the grain and biomass of major cereals, including sorghum, is fundamental to developing breeding and selection methods aimed at increasing bioavailable minerals and improving biofuel suitability and seed nutritional quality. A combinatorial strategy …

The African American Male Achievement Dilemma Through The Eyes Of The African American Male Superintendent, J.R. Falor Green

Theses and Dissertations

This research study explores the perspective of African American male superintendents on the African American male achievement dilemma. How do African American male superintendents theorize and respond to the underachievement of African American male students? Do their experiences give them greater insight, and how has this potential insight contributed to the implementation of initiatives that have improved the performance of this subgroup? Three major theoretical perspectives were explored during my review of the literature. Critical Race, Social Reproduction, and Oppositional Culture Theory encompassed the most consistent themes during my research, and helped to situate the study within the broader education …

The Daryl Atkins Story, Mark E. Olive

William & Mary Bill of Rights Journal

No abstract provided.

Challenges Of Conveying Intellectual Disabilities To Judge And Jury, Caroline Everington

William & Mary Bill of Rights Journal

No abstract provided.

The True Legacy Of Atkins And Roper: The Unreliability Principle, Mentally Ill Defendants, And The Death Penalty’S Unraveling, Scott E. Sundby

William & Mary Bill of Rights Journal

In striking down the death penalty for intellectually disabled and juvenile defendants, Atkins v. Virginia and Roper v. Simmons have been understandably heralded as important holdings under the Court’s Eighth Amendment jurisprudence that has found the death penalty “disproportional” for certain types of defendants and crimes. This Article argues, however, that the cases have a far more revolutionary reach than their conventional understanding. In both cases the Court went one step beyond its usual two-step analysis of assessing whether imposing the death penalty violated “evolving standards of decency.” This extra step looked at why even though intellectual disability and youth …

Everyone Forgets About The Third Amendment: Exploring The Implications On Third Amendment Case Law Of Extending Its Prohibitions To Include Actions By State Police Officers, Samantha A. Lovin

William & Mary Bill of Rights Journal

No abstract provided.

State V. Casad Respondent's Brief Dckt. 41613

Not Reported

No abstract provided.

Women In The Crowd Of Corporate Directors: Following, Walking Alone, And Meaningfully Contributing, Joan Macleod Heminway

William & Mary Journal of Race, Gender, and Social Justice

No abstract provided.

Mail Order Feminism, Marcia Zug

William & Mary Journal of Race, Gender, and Social Justice

This Essay will argue that America’s current marriage crisis is a problem that could be solved by encouraging mail order marriages. Specifically, Part I of this Article will show how the current marriage crisis is the result of an increasing educational gap between American men and women that is leaving less educated men with few marriage prospects. It will further argue that the loss of marriage prospects is concerning both because marriage is often the social institution that supports men as their job prospects falter and because it has the potential to create an angry and dangerous underclass of men …

Feminist Legal Theory As A Way To Explain The Lack Of Progress Of Women’S Rights In Afghanistan: The Need For A State Strength Approach, Isaac Kfir

William & Mary Journal of Race, Gender, and Social Justice

Cultural and religious practices are critical to explaining Afghanistan’s dreadful reputation concerning the preservation, protection, and promotion of women’s rights. Those advocating misogynistic practices assert that the calls for reforms challenge their religion and culture, while also claiming that many women’s issues exist within the private realm. Accordingly, they assert that reforms that aim at addressing disempowerment are not vital to the state and go beyond the established limits of state authority. Building on feminist legal theory, which distinguishes between the public and private spheres, I argue in Afghanistan misogynistic and discriminatory practices stem from contrived cultural and religious norms. …

Procedurally Criminal: How Peremptory Challenges Create Unfair And Unrepresentative Single-Gender Juries, Chelsea V. King

William & Mary Journal of Race, Gender, and Social Justice

No abstract provided.

Suicide In The Name Of Honor: Why And How U.S. Asylum Law Should Be Modified To Allow Greater Acceptance Of Honor-Violence Victims To Prevent “Honor Suicides”, Ayla M. Kremen

William & Mary Journal of Race, Gender, and Social Justice

No abstract provided.

A Travesty Of Justice: Revisiting Harris V. Mcrae, Jill E. Adams, Jessica Arons

William & Mary Journal of Race, Gender, and Social Justice

No abstract provided.

School-Based Sexuality Education, Gender, And Relationship Self-Efficacy: A Moderated-Mediation Analysis Of Sexual Behavior In First-Year College Students, Sara C. Schmidt

Theses and Dissertations

While the effectiveness at abstinence-only versus comprehensive sexuality education in preventing adolescent risky sexual behavior is widely researched, little is known about whether material learned in secondary school sexuality education classes impacts emerging adult sexual behavior in the college environment. Furthermore, research suggests that self-efficacy – or beliefs in one’s abilities to organize and execute actions – may be more critical than knowledge or skills in terms of how individuals enact behavior. We hypothesized a moderated-mediation effect by which the causal impact of type of sexuality education on four different sexual behaviors during the first year in college is transmitted …