Digital Commons Network^™

Antibacterial And Antioxidative Properties Of Essential Oils From Armoise (Artemisia Herba-Alba), Bay (Laurus Nobilis) And Rose Geranium (Pelargonium Capitatum X Radens) In Vitro, Ragina B. Rafiq

Theses

The prevalence of food contamination by pathogenic bacteria resulting in foodborne illness has raised concern to the food industry. In addition, oxidation in food, which affects the shelf life and quality of the food through the formation of off odor and off flavor, is another concern to the food industry. Nitrates, sulfates, benzoates of sodium and potassium, butylated hydroxytoluene (BHT) and butylated hydroxyanisole (BHA) are commonly used as preservatives in the food industry. However, long-term safety issues of synthetic preservatives in human health along with negative perception of consumers have lead researchers to find alternative natural preservatives. The purpose of …

Annual Report 2014, Eastern Illinois University

Lumpkin College Annual Reports

This 2014 Annual Report records the achievements, outreach activities, and student honors work of the Eastern Illinois University's Lumpkin College of Business and Applied Sciences. It also includes reports from the School of Business, the School of Family and Consumer Science, the School of Technology, and the department of Military Science.

Inverse Association Of Colorectal Cancer Prevalence To Serum Levels Of Perfluorooctane Sulfonate (Pfos) And Perfluorooctanoate (Pfoa) In A Large Appalachian Population, Kim E. Innes, Jeffrey H. Wimsatt, Stephanie Frisbee, Alan M. Ducatman

Faculty & Staff Scholarship

Background

Perfluorooctanoate (PFOA) and perfluorooctane sulfonate (PFOS) are persistent environmental contaminants that affect metabolic regulation, inflammation, and other factors implicated in the development and progression of colorectal cancer (CRC). However, the link between these compounds and CRC remains unknown. In this cross-sectional study, we investigated the association of CRC diagnosis to PFOA and PFOS blood levels in a large Appalachian population.

Methods

Participants were 47,359 adults ≥ 21 years of age and residing in six PFOA-contaminated water districts in the mid-Ohio Valley (N = 47,151 cancer-free adults, 208 cases of primary CRC). All participants completed a comprehensive health survey between …

Predictors Of Weight Loss Maintenance Following An Insurance-Sponsored Weight Management Program, Christiaan Abildso, Olivier Schmid, Megan Byrd, Sam Zizzi, Alessandro Quartiroli, Sean J. Fitzpatrick

Faculty & Staff Scholarship

Intentional weight loss among overweight and obese adults (body mass index ≥ 25 kg/m²) is associated with numerous health benefits, but weight loss maintenance (WLM) following participation in weight management programming has proven to be elusive. Many individuals attempting to lose weight join formal programs, especially women, but these programs vary widely in focus, as do postprogram weight regain results. We surveyed 2,106 former participants in a community-based, insurance-sponsored weight management program in the United States to identify the pre, during, and post-intervention behavioral and psychosocial factors that lead to successful WLM. Of 835 survey respondents (39.6% response …

College Catalog, 2014-2015, Graduate, Buffalo State College

Academic Catalogs, 1871-2018

No abstract provided.

College Catalog, 2014-2015, Buffalo State College

Academic Catalogs, 1871-2018

No abstract provided.

Escherichia Coli Pathotypes Occupy Distinct Niches In The Mouse Intestine, Jessica P. Meador, Matthew E. Caldwell, Paul S. Cohen, Tyrrell Conway

Cell and Molecular Biology Faculty Publications

Since the first step of the infection process is colonization of the host, it is important to understand how Escherichia coli pathogens successfully colonize the intestine. We previously showed that enterohemorrhagic O157:H7 strain E. coli EDL933 colonizes a niche in the streptomycin-treated mouse intestine that is distinct from that of human commensal strains, which explains how E. coli EDL933 overcomes colonization resistance imparted by some, but not all, commensal E. coli strains. Here we sought to determine if other E. coli pathogens use a similar strategy. We found that uropathogenic E. coli CFT073 and enteropathogenic E. coli E2348/69 occupy intestinal …

Annual Report From The University Library, 2013-2014, Peter Gavin Ferriby

Library Annual Report

Annual report for the academic year 2013-2014.

Dietary Supplement Labeling: Cognitive Biases, Market Manipulation & Consumer Choice, Michael Mccann

Law Faculty Scholarship

There exists increasing concern that the Dietary Supplements Health and Education Act (DSHEA) has proven ineffective. Much of the concern regards the disparity in legislative treatment between dietary supplements, foods, and pharmaceutical drugs. Namely, while pharmaceutical drugs must undergo years of costly pre-market testing, most supplements, like foods, can immediately enter the market, and only after repeated instances of adverse reactions can the Food and Drug Administration (FDA) remove them. Such a framework appears to belie both consumer expectations and marketing strategies, as supplements tend to be most perceived for their apparent medicinal qualities. This philosophy of waiting for a …

Overcoming India’S Food Security Challenges: The Role Of Intellectual Property Management And Technology Transfer Capacity Building, Stanley Kowalski, Aarushi Gupta, Ifica Mehra

Law Faculty Scholarship

The growth of the Indian economy after Independence has had little impact on the food security of the country. The paper analyses the development of advanced crop varieties through the use of agricultural technologies (hereinafter "agbiotech") within the technology transfer system, a framework which comprises of the interactions of intellectual property rights law and agricultural research and development in India. Through this, the author argues that agricultural innovation in India is failing due to the absence of connections within the technology transfer system and advocates for the creation of a national program aimed at advancing IP and tech-transfer capacity in …

Student Handbook 2014-15, Dmacc

Student Handbooks

No abstract provided.

Cyclodextrin-Promoted Energy Transfer For Broadly Applicable Small-Molecule Detection, Nicole Serio, Chitapom Chanthalyma, Lindsey Prignano, Mindy Levine

Chemistry Faculty Publications

Reported herein is the development of non-covalent, proximity-induced energy transfer from small-molecule toxicants to organic fluorophores bound in the cavity of γ-cyclodextrin. This energy transfer occurs with exceptional efficiency for a broad range of toxicants in complex biological media, and is largely independent of the spectral overlap between the donor and acceptor. This generally applicable phenomenon has significant potential in the development of new turn-on detection schemes.

Mississippi State University - Student Enrollment Profile - Fall 2014, Mississippi State University Office Of Institutional Research And Effectiveness

Enrollment Profiles

No abstract provided.

The Impact Of Diet On Goat Rumen Microbes And Innate Immune Gene Expression, Ahmed Abdalla

Theses

Gastrointestinal nematodes in goats have developed resistance to chemical anthelmintics, resulting in the need for alternative control strategies. One approach is incorporation of Sericea Lespedeza (SL) as high quality forage that suppresses these parasites in goats due to its high condensed tannin (CT) content. However, little is known about its effect on rumen microorganisms and innate immunity in goats. A diverse collection of microorganisms is found in the goat rumen and Bifidobacteria is one of the important organisms in the immunity, yet its presence in the goat rumen is not fully studied. The objective of this study was to evaluate …

Behavioral Health Guidelines For Shelter-In-Place And Evacuation Of Assisted Living And Long-Term Care Facilities, Denise Bulling, Stacey Hoffman, Robin Zagurski

University of Nebraska Public Policy Center: Publications

This document is intended to assist Nebraska facilities to meet behavioral health needs of residents in assisted living or long-term care in the event of a disaster or other emergency requiring sheltering in place or evacuation. Disasters are typically chaotic and noisy. This can be overwhelming for residents, caregivers and responders. Facility administrators probably have plans already in place for most emergencies including evacuation and sheltering in place. Practicing the procedures related to implementing these plans will help residents and staff members deal with the chaos of an actual disaster better and could lessen everyone’s anxiety. Having a specific plan …

Determining The Presence, Genetic Variability, And Function Of Cytolethal Distending Toxin In Samoa Strains Of Haemophilus Ducreyi, Andrea Faye Anstead

Theses

Haemophilus ducreyi is the causative agent of the genital ulcerative disease chancroid. Chancroid is an important facilitator for increased transmission of HIV amongst heterosexuals. Chancroid is endemic to Asia, Africa, and Latin America, but there have been several outbreaks within the United States. Chancroidal ulcers are categorized as soft, painful, bloody ulcers that may remain chronic if untreated. H. ducreyi produces and secretes a cytolethal distending toxin (CDT) that causes various cell types to undergo cell cycle arrest or apoptosis. The CDT holotoxin consists of three genes: cdtA, cdtB, and cdtC. In 2006, the first report of nonsexual transmission of …

Effectiveness Of Lurasidone In Schizophrenia Or Schizoaffective Patients Switched From Other Antipsychotics: A 6-Month, Open-Label, Extension Study, L. Citrome, P. J. Weiden, J. P. Mcevoy, C. U. Correll, J. Cucchiaro, J. Hsu, A. Loebel

Journal Articles

Objective. To evaluate the long-term safety and tolerability of lurasidone in schizophrenia and schizoaffective disorder patients switched to lurasidone. Method. Patients in this multicenter, 6-month open-label, flexible-dose, extension study had completed a core 6-week randomized trial in which clinically stable, but symptomatic, outpatients with schizophrenia or schizoaffective disorder were switched to lurasidone. Patients started the extension study on treatment with the same dose of lurasidone taken at study endpoint of the 6-week core study; following this, lurasidone was flexibly dosed (40-120 mg/day), if clinically indicated, starting on Day 7 of the extension study. The primary safety endpoints were the proportion …

Are Exotic Herbivores Better Competitors? A Meta-Analysis, Laura Radville, Liahna Gonda-King, Sara Gomez, Ian Kaplan, Evan L. Preisser

Biological Sciences Faculty Publications

Competition plays an important role in structuring the community dynamics of phytophagous insects. As the number and impact of biological invasions increase, it has become increasingly important to determine whether competitive differences exist between native and exotic insects. We conducted a meta-analysis to test the hypothesis that native/exotic status affects the outcome of herbivore competition. Specifically, we used data from 160 published studies to assess plant-mediated competition in phytophagous insects. For each pair of competing herbivores, we determined the native range and coevolutionary history of each herbivore and host plant. Plant-mediated competition occurred frequently, but neither native nor exotic insects …

Using Non-Dietary Gastropods In Coastal Shell Middens To Infer Kelp And Seagrass Harvesting And Paleoenvironmental Conditions, Amira F. Ainis, René Vellanoweth, Queeny G. Lapeña, Carol S. Thornber

Biological Sciences Faculty Publications

Archaeologists analyzing shell middens typically focus on larger (>2 cm) mollusks to examine subsistence practices, impacts on littoral habitats, and paleoenvironmental conditions as well as a host of other natural and cultural phenomena. Small (<2 cm), non-dietary gastropods in archaeological shell middens also provide important clues regarding human resource procurement in littoral areas and coastal paleoenvironments. We present data from two sites on the California Channel Islands to demonstrate the range of information that can be gained by analyzing small gastropod shells. Identifications revealed the remains of over 4500 non-dietary small gastropods from 75 taxa. Human harvesting of marine macrophytes is suggested by the presence of 18 species that are predominantly associated with seaweeds and seagrasses. Quantification measures revealed high diversity and equitability indices, oscillating taxonomic richness, and decreasing densities through time at both sites. Likelihood ratio tests revealed differences in assemblage composition between Early Holocene and later components at one site, and demonstrated similarities in the relative composition of non-dietary shell assemblages between both sites during the Middle Holocene. Incorporating detailed studies of less conspicuous “incidental” shellfish remains in archaeological midden studies has the potential to contribute to our understanding of past human land use practices and littoral paleoecology. Our findings are applicable to archaeologists working in coastal settings around the world, as well as marine ecologists interested in intertidal paleo-habitats and kelp forest ecosystems.

Intraspecific Variation In Vertical Habitat Use By Tiger Sharks (Galeocerdo Cuvier) In The Western North Atlantic, Jeremy J. Vaudo, Bradley M. Wetherbee, Guy Harvey, Richard S. Nemeth, Choy Aming, Neil Burnie, Lucy A. Howey-Jordan, Mahmood S. Shivji

Biological Sciences Faculty Publications

Tiger sharks (Galeocerdo cuvier) are a wide ranging, potentially keystone predator species that display a variety of horizontal movement patterns, making use of coastal and pelagic waters. Far less, however, is known about their vertical movements and use of the water column. We used pop‐up satellite archival tags with two data sampling rates (high rate and standard rate tags) to investigate the vertical habitat use and diving behavior of tiger sharks tagged on the Puerto Rico–Virgin Islands platform and off Bermuda between 2008 and 2009. Useable data were received from nine of 14 sharks tagged, tracked over a …

Leveraging Practice-Based Research Networks To Accelerate Implementation And Diffusion Of Chronic Kidney Disease Guidelines In Primary Care Practices: A Prospective Cohort Study, James W. Mold, Cheryl B. Aspy, Paul D. Smith, Therese M. Zink, Lyndee Knox, Paula Darby Lipman, Margot Krauss, D. Robert Harris, Chester Fox, Leif I. Solberg, Rachel Cohen

Family Medicine Faculty Publications

Background

Four practice-based research networks (PBRNs) participated in a study to determine whether networks could increase dissemination, implementation, and diffusion of evidence-based treatment guidelines for chronic kidney disease by leveraging early adopter practices.

Methods

Motivated practices from four PBRNs received baseline and periodic performance feedback, academic detailing, and weekly practice facilitation for 6 months during wave I of the study. Each wave I practice then recruited two additional practices (wave II), which received performance feedback and academic detailing and participated in monthly local learning collaboratives led by the wave I clinicians. They received only monthly practice facilitation. The primary outcomes …

On The Association Of Common And Rare Genetic Variation Influencing Body Mass Index: A Combined Snp And Cnv Analysis, Roseann Peterson, Hermine Maes, Peng Lin, John R. Kramer, Victor M. Hesselbrock, Lance O. Bauer, John I. Nurnberger, Howard J. Edenberg, Danielle Dick, Bradley T. Webb

Psychiatry Publications

Background As the architecture of complex traits incorporates a widening spectrum of genetic variation, analyses integrating common and rare variation are needed. Body mass index (BMI) represents a model trait, since common variation shows robust association but accounts for a fraction of the heritability. A combined analysis of single nucleotide polymorphisms (SNP) and copy number variation (CNV) was performed using 1850 European and 498 African-Americans from the Study of Addiction: Genetics and Environment. Genetic risk sum scores (GRSS) were constructed using 32 BMI-validated SNPs and aggregate-risk methods were compared: count versus weighted and proxy versus imputation.

Results The weighted SNP-GRSS …

Virginia Commonwealth University Graduate And Professional Programs Bulletin Courses [2014], Virginia Commonwealth University

VCU Bulletins

Listing of professional and graduate courses for 2014-2015.

Character Evolution And Microbial Community Structure In A Host-Associated Grasshopper, Tyler Raszick

Electronic Theses and Dissertations

The spotted bird grasshopper, Schistocerca lineata Scudder (Orthoptera: Acrididae), is a widely distributed species found throughout most of the continental United States and southern Canada. This species is known to be highly variable in morphology, with many distinct ecotypes across its native range. These ecotypes display high levels of association with type-specific host plants. Understanding the evolutionary relationships among different ecotypes is crucial groundwork for studying the process of ecological differentiation. I examine four ecotypes from morphological and phylogeographic perspectives, and look for evidence of distinct evolutionary lineages within the species. I also begin to explore the potential role of …

Genetics Of Rheumatoid Arthritis Contributes To Biology And Drug Discovery, Y. Okada, D. Wu, G. Trynka, T. Raj, C. Terao, K. Ikari, Y. Kochi, K. Ohmura, P. K. Gregersen, R. M. Plenge, +85 Additional Authors

Journal Articles

A major challenge in human genetics is to devise a systematic strategy to integrate disease-associated variants with diverse genomic and biological data sets to provide insight into disease pathogenesis and guide drug discovery for complex traits such as rheumatoid arthritis (RA). Here we performed a genome-wide association study meta-analysis in a total of >100,000 subjects of European and Asian ancestries (29,880 RA cases and 73,758 controls), by evaluating approximately 10 million single-nucleotide polymorphisms. We discovered 42 novel RA risk loci at a genome-wide level of significance, bringing the total to 101 (refs 2 - 4). We devised an in silico …

Integration Of Sequence Data From A Consanguineous Family With Genetic Data From An Outbred Population Identifies Plb1 As A Candidate Rheumatoid Arthritis Risk Gene, Y. Okada, D. Diogo, J. D. Greenberg, F. Mouassess, W. A. L. Achkar, R. S. Fulton, J. C. Denny, N. Gupta, P. K. Gregersen, R. M. Plenge, +38 Additional Authors

Journal Articles

Integrating genetic data from families with highly penetrant forms of disease together with genetic data from outbred populations represents a promising strategy to uncover the complete frequency spectrum of risk alleles for complex traits such as rheumatoid arthritis (RA). Here, we demonstrate that rare, low-frequency and common alleles at one gene locus, phospholipase B1 (PLB1), might contribute to risk of RA in a 4-generation consanguineous pedigree (Middle Eastern ancestry) and also in unrelated individuals from the general population (European ancestry). Through identity-by-descent (IBD) mapping and whole-exome sequencing, we identified a non-synonymous c.2263G. C (p.G755R) mutation at the PLB1 gene on …

Interaction And Protection Of Antimicrobial Compounds With Carbohydrate-Based Colloidal Systems For Improved Food Safety, Preetam Sarkar

Open Access Dissertations

The food processing industry has focused on using conventional methods for food preservation. However, the recurring incidence of food borne illnesses and outbreaks due to pathogenic or spoilage organisms have called for creation of novel intervention strategies. In recent years, antimicrobial compounds from natural sources are gaining significant importance in improving food safety and security. However, antimicrobials suffer from extensive degradation when applied to complex food systems due to several specific or non-specific interactions. There is an urgent need for the protection of such antimicrobials to prolong their activity in foods. One strategy of achieving the goal is by the …

Giving The Honey Bear A New Home, Brianna Rhoads

Biology Posters

No abstract provided.

2013-2014 Annual Report, Tennessee. Department Of Labor And Workforce Development

Annual Reports

This report highlights the accomplishments of the Department of Labor and Workforce Development for the fiscal year.

The Effect Of Sodium Bicarbonate Ingestion On Back Squat And Bench Press Exercise To Failure, Michael J. Duncan, Anthony Weldon, Michael J. Price

Faculty of Management & Hospitality (THEi)

This study examined the acute effects of NaHCO3 ingestion on repetitions to failure and rating of perceived exertion in the back squat and bench press in trained men. Eight resistance-trained men took part in this double-blind, randomized crossover experimental study whereby they ingested NaHCO3 (0.3 g[middle dot]kg-1 body mass) or placebo (sodium chloride NaCl: 0.045 g[middle dot]kg-1 body mass) solution 60 minutes before completing a bout of resistance exercise (3 sets of bench press and back squat exercise to failure at an intensity of 80% 1 repetition maximum). Experimental conditions were separated by at least 48 hours. Participants completed more …