Digital Commons Network^™

The Rule Of Law In The Recent Jurisprudence Of The Ecj, Thomas Von Danwitz

Fordham International Law Journal

No abstract provided.

Characterization Of The Disulfide In The Ectodomain Of Anthrax Toxin Receptor 2, Pedro Raymundo Jacquez

Open Access Theses & Dissertations

Anthrax toxin receptors act as molecular clamps or switches that control anthrax toxin entry, pH-dependent pore formation, and translocation of enzymatic moieties across the endosomal membranes. The ectodomain of anthrax toxin receptor 2 (ANTXR2) is composed of a von Willebrand factor A (VWA) domain that binds to anthrax toxin protective antigen (PA) and a newly defined immunoglobulin-like (Ig) domain, in which the disulfide bonds are required for PA pore formation and for the folding of ANTXR2. While the VWA domain has been well characterized, the structure and function of the whole ectodomain (VWA-Ig) are poorly defined, this is mainly due …

Digital Biliteracy: Digital Technologies As Homes For Arab Immigrant Children's Biliteracy Development, Laila Al-Salmi

Open Access Theses & Dissertations

The revolution of digital technologies and children's increasing access to them is

impacting the literacy development of children around the world. However, few studies have investigated the relationship between digital technologies and immigrant children's biliteracy development. The purpose of this study was to understand the digital literacy practices of Arab pre-kindergarten children and how these shape biliteracy development in Arabic and English. Tomake sense of the emergent biliteracy of these young participants, the study proposed Digital Biliteracy, a theoretical framework that draws on elements of New Literacy Studies, MultimodalLiteracies, Digital Literacies and Situated Learning Theory.

The study employed a qualitative …

Biochemical Characterization Of Four Distinct Proteins, Gustavo A. Avila

Open Access Theses & Dissertations

Proteins are ubiquitous in all living organisms, executing the majority of cellular functions in distinct ways. Understanding a protein's role necessitates investigating its structure and function, which are closely related. My research couples these two aspects by delving into the biochemical and structural characterization of proteins in four distinct systems, all playing central roles in numerous significant disease progressions. These four original research endeavors were all targeted for structural studies with a unifying relationship to establish our new structural biochemistry lab. These four systems are: (1) Gam1, an early adenovirus protein globally inhibiting host SUMOylation; (2) Anthrax toxin complexed with …

Psychographic Characteristics And Health Behaviors In Young Adults, Jose Alonso Cabriales

Open Access Theses & Dissertations

Tobacco use remains the leading cause of preventable death in the U.S. Non trivial smoking rates are observed among young adults and Hispanics, particularly as light and intermittent smoking is on the rise. Additionally, the assessment of other health behaviors including alcohol use, physical activity, and dietary practices seems warranted in young adults. The primary aim of this study was to identify clusters of individuals based on psychographics (e.g., lifestyle, preferences, personality characteristics), and their relation to tobacco use within a primarily Hispanic young adult border sample. Secondary aims were the assessment of group differences with respect to alcohol use, …

Through The Eyes Of The Dead Others, Isaac Aaron Ceniceros

Open Access Theses & Dissertations

I use Edith Wyschogrod's figure of the heterological historian to argue that we have a responsibility to learn from the "dead others" of the past in order to better apply in practical ways the lessons we learn from history. I draw on an interpretation of Nietzsche's view on historiography, to examine the claims of Hegel's dialectic, namely, that the Ideal Absolute for which Spirit pines, is actually achievable, particularly through the advent of the Internet. Beginning with a relatively well-known interpretation of Hegel's philosophy of history, Fukuyama's, I show how Hegel's dialectic takes shape in Fukuyama's interpretation as a negative …

Effects Of Electrical Pulse Stimulation On In Vitro Measurement Of Mitochondrial Content And Lipid In Human Myotubes, Daniel Alberto Conde

Open Access Theses & Dissertations

It has been previously shown that human myotubes retain certain in vivo characteristics of the donors. Furthermore, we have shown that Electrical pulse stimulation (EPS), an in vitro exercise mimetic, increases mitochondrial and lipid content in cultured human myotubes after 24 hr. of stimulation. Purpose: We aimed to examine the EPS induced adaptations to lipid, mitochondrial, and Glucose transporter 4 (GLUT4) content using human myotubes. Methods: EPS was applied to myotubes for 60 min (bipolar pulses of 100 Hz, 30V, every 5 seconds), 24 hr. or 48 hr. (single bipolar pulses of 1 Hz for 2 ms; 30V) and were …

Spingolipid Metabolism In A Reptillian Protozoan, Entamoeba Invadens, Duran Dogan Debons

Open Access Theses & Dissertations

Entamoeba invadens (hereinafter E. invadens) is an anaerobic parasitic protozoan that can be found in water and soil. Although the host organisms for this parasite are snakes, lizards, and other reptile species, the parasite is morphologically identical to Entamoeba histolytica, a causative agent of human amebiasis. Entamoeba inavdens exists in two morphological forms--(1) a replicative trophozoite, and (2) a relatively dormant cyst. While the transformation of cyst to trophozoites (called "excystation") takes place in the stomach, the differentiation of trophozoites to cyst (known as "encystation"), occurs in the small intestine. Unlike the cyst, a trophozoite is unable to survive …

Global Sphingolipid Profile Of Giardia Lamblia During Stage Differentiation: The Influence Of Sphingomyelin Abundance On Viable Cyst Production, Trevor Thomas Duarte

Open Access Theses & Dissertations

Giardia lamblia is a protozoan parasite and a major cause of the waterborne-illness, giardiasis, worldwide. Giardiasis is endemic in developing countries and is a leading cause of non-viral- and non-bacterial-associated intestinal disorders. Acute symptoms of giardiasis include diarrhea, cramps, and malabsorption. The disease is often self-limiting, although the infection can result in long-term disorders such as chronic fatigue, stunted cognitive skills, and failure to thrive even after the parasite has been cleared.

This parasite exists in two morphologic forms--infective trophozoites and transmissible, water-resistant cyst, which is passed by the fecal-oral route and is likely to be spread by contaminated drinking …

Optimized Integrated Software Package For Classification Of Small Airway Dysfunction Using Genetic Algorithms, Elias Estrada

Open Access Theses & Dissertations

Due to the similarity in the symptoms of respiratory disorders, an accurate diagnosis could be a difficult task. Regarding asthma as the main focus of this research, early detection of small airway impairment could represent a better opportunity for timely diagnosis. An integrated software package (ISP) based on the impulse oscillometry technique, has been developed to serve as an important tool for clinicians during classification of asthma severities on children [1]. The current version of the ISP was tested with data obtained during several years by Dr. Homer Nazeran and Dr. Michael Goldman from 110 Hispanic children [2], providing an …

3d Printed Spatially Variant Metamaterials, Cesar Roman Garcia

Open Access Theses & Dissertations

The recent advancement in 3D printing has created a new way to design electronics and electromagnetic devices. This allows for a new breed of non-planar designs to be used, fully exploiting all three dimensions like never before. More functions can be fit into the same amount of space, products with novel form factors can be more easily manufactured, interconnects can be routed more smoothly, interfaces can be better implemented, electrical and mechanical functions can be comingled, and entirely new device paradigms will be invented. When departing from traditional planar topologies many new problems arise like signal integrity, crosstalk, noise, and …

Why Ricker Wavelets Are Successful In Processing Seismic Data: Towards A Theoretical Explanation, Afshin Gholamy Salehabady

Open Access Theses & Dissertations

In many engineering applications ranging from engineering seismology to petroleum engineering and civil engineering, processing seismic data plays a key role. In processing seismic data, it turns out to be very efficient to describe the signal's spectrum as a linear combination of Ricker wavelet spectra.

In this Thesis, we provide a possible theoretical explanation for this empirical efficiency. Specifically, signal propagation through several layers is discussed, and it is shown that the Ricker wavelet is the simplest non-trivial solution for the corresponding data processing problem, under the condition that the described properties of the approximation family are satisfied.

Sisma, Paul Jesus Guillen Delgado

Open Access Theses & Dissertations

En Sobre la violencia: seis reflexiones marginales, Slavoj Zizek cuenta la anécdota de un hombre sospechoso de robar en el trabajo. Cada tarde los vigilantes inspeccionan su carretilla, pero nunca encuentran nada. Un día descubren el ardid: lo que el trabajador está robando son las carretillas. He tratado en este libro titulado SISMA de actuar como ese obrero frente al lenguaje y el Poder. El lenguaje que es una manifestación humana debe ser "robado" de los aparatos ideológicos del Estado (Althusser) y del Poder (Foucault). Mi investigación poetica se centra en el terremoto que asoló parte del Perú en el …

Experiencias De Discriminación Lingüística En Contra De Inmigrantes De Primera Generación En El Paso, Tx, Maria Asuncion Gutierrez

Open Access Theses & Dissertations

El poder simbólico del idioma, la racialización y la discriminación lingüística, no sólo afectan la forma en que las personas son tratadas dentro de una sociedad, también influencian la identidad de éstas y la manera en que son tratadas como parte de un determinado grupo. Este estudio revela las diferentes formas en que el idioma inglés es usado como poder simbólico en contra de la gente, racializándola y discriminándola porque no lo habla o lo habla con acento mexicano, ejerciendo de esta manera violencia simbólica. En este sentido, las/los inmigrantes de primera generación que no saben hablar inglés o lo …

A Comparative Approach To Assessing The Functional And Structural Characteristics Of Human Fkbp52 In The Regulation Of Steroid Hormone Receptor Signaling Pathway, Diondra Crystal Harris

Open Access Theses & Dissertations

The 52 kDa FK506 binding protein (h52) is a key positive regulator of Androgen Receptor (AR) in cellular and animal models and is an attractive target for the treatment of prostate cancer. Human FKBP52 is a known regulatory protein and co-chaperone that has been shown to play an important role in the regulation of the AR signaling pathway, and in the development of the male sexual phenotype. Cellular studies in mammalian and yeast cells reveal that FKBP52 is a positive regulator of AR, glucocorticoid receptor (GR), and progesterone receptor (PR), potentiating receptor-mediated gene expression up to 60-fold in some systems. …

Design Of Three Different Particle Size Distributions In Silver Paste Through Computer Simulation For Higher Electrical Conductivity, Kyungdeok Jang

Open Access Theses & Dissertations

In the field of printed electronics technology, researchers have tried to print highly conductive electrodes with fine width and height in order to manufacture high performance devices.

The purpose of this research is to print particle monolayer silver patterns which have better electrical conductivity than existing ones. The key idea of this experiment is to analyze silver inks with different sized particles. Let us consider a particle monolayer pattern printed with silver ink consisting of mono-sized particles. Inside of the pattern, there are some vacant spaces between the particles, which can lead to low electrical conductivity and discontinuity of the …

Art And Hyperreality, Alfredo Martin-Perez

Open Access Theses & Dissertations

My Thesis pertains to philosophy of art. Its main purpose is a reconsideration of the notion of art as a response to claims stating the end of art, as in the case of the writings on hyperreality, stating that the transformation of reality, has resulted in a world that is permeated with a virtual reality that replaces traditional schemas for ways of living in the world, that valued the originality of art.

In the setting up of the subject, I will briefly mention descriptions of both reality and hyperreality, and the developments in art throughout the modern, and post modern …

Light Scattering From Aerosol Particles In The El Paso Del Norte Region / The Effect Of Humidity, Richard Medina Calderon

Open Access Theses & Dissertations

Atmospheric aerosols play an important role in climate forcing, through scattering and absorption of the incoming solar radiation. The extinction of light by the presence of atmospheric aerosols was studied using two first-principle models, and corresponding computer codes. In the first model the extinction of light from irregularly shaped aerosol particles was analyzed. In the second model it was assumed that the irregularly shaped aerosol particles were covered by a film of water, and the hygroscopicity and the extinction of light by the aerosols was analyzed. These models were then applied to the Paso del Norte region and their light …

Super Resolution Pump-Probe Microscopy With Point Spread Function Engineering, Farzaneh Mohajerani

Open Access Theses & Dissertations

Since the last decade, new techniques have made optical microscopy break the diffraction barrier of resolution where all of them are based on molecular fluorescence. Among them, stimulated emission depletion microscopy (STED) has reached less than 25 nm resolution by engineering the point spread function. However, the existing obstacles associated with fluorescence tagging makes it desirable to achieve label-free imaging. Recently the pump-probe method has made it possible to obtain image contrast from molecular absorption and vibration signatures that do not depend on fluorescence. We introduce Super Resolution Pump-Probe Microscopy (SRPPM), in which we combine both PSF engineering method and …

Structural Investigation Of The Molecular Chaperonin Tf55 From Thermophilic Archaeon Sulfolobus Solfataricus, Sanjay Kumar Molugu

Open Access Theses & Dissertations

Chaperonins are ubiquitous multi-subunit macromolecules that mediate the folding and assembly of certain proteins that cannot fold properly in vivo. The Archaea bacterium Sulfolobus solfataricus encodes for three chaperonin complexes formed from three different, but closely related subunits named alpha,betaand Gamma. These subunits form a homo-18mer composed of all beta subunits at temperatures ranging between 80oC-85oC, a hetero-16mer composed of alpha and beta subunits at temperatures ranging between 70oC-75oC and a hetero 18mer composed of alpha, beta and gamma subunits at temperatures of 60oC. Structures exist for the chaperonin TF55 all-beta complex and for the TF55 alpha-beta complex but not …

Evaluation Of Static And Dynamic Postural Control In Athletes With Concussions During Recovery, Nicholas Murray

Open Access Theses & Dissertations

Approximately seventy-six percent of individuals with a sport-related concussion present with reduced balance. Current Return-to-Play (RTP) protocols rely heavily on measures of static balance that are not environmentally relevant. However, due to the variable nature of symptom presentation, research has not clearly defined a requisite time for balance recovery following a sport-related concussion. The use of novel procedures such as monitoring postural control during an environmentally relevant dynamic balance tasks could refine the timeline for recovery of postural control and aid in mitigating the potential severe consequences of Second Impact Syndrome. Therefore, the purpose of this study was to investigate …

Functional Genomic And Proteomic Analysis Of Highly Drug Resistant Chronic Myeloid Leukemia, Derrick Matthew Oaxaca

Open Access Theses & Dissertations

Chronic Myeloid Leukemia (CML) has served as a model for how cancer can be selectively targeted with advanced forms of chemotherapies known as kinase inhibitors. Such new therapies have significantly altered the field of oncology and have led to monumental increases in both survival rates and quality of life for cancer patients. However, approximately one-third of CML patients will go on to develop drug resistance against major kinase inhibitors. Along with this, other cancers are showing increased incidences of drug resistance. Understanding how these cancers, such as CML, overcome drug sensitivity is of major importance within the clinic. To predict …

Design And Evaluation Of A High Temperature/Pressure Supercritical Carbon Dioxide Direct Tubular Receiver For Concentrating Solar Power Applications, Jesus Daniel Ortega

Open Access Theses & Dissertations

This work focuses on the development of a solar power thermal receiver for a supercritical-carbon dioxide (sCO2), Brayton power-cycle to produce ~1 MWe. Closed-loop sCO2 Brayton cycles are being evaluated in combination with concentrating solar power to provide higher thermal-to-electric conversion efficiencies relative to conventional steam Rankine cycles. High temperatures (923 - 973 K) and pressures (20 - 25 MPa) are required in the solar receiver to achieve thermal efficiencies of ~50%, making concentrating solar power (CSP) technologies a competitive alternative to current power generation methods. In this study, the CSP receiver is required to achieve an outlet temperature of …

The Big [Motion] Picture: Analyzing The Factors Affecting The International Motion Picture Industry, Dalila Salazar

Open Access Theses & Dissertations

The motion picture industry is one of the largest private sector employers in the United States, supporting 1.9 million jobs, and providing its workforce approximately $104 billion in total wages in 2011 (Motion Picture Association of America, 2012b). With U.S. films distributed in over 140 countries, not only is the industry successful domestically, it is one of the country's leading exports, reaping more than $23.9 billion in 2012 (Motion Picture Association of America, 2012a). Despite the importance of the global marketplace, we know very little about the factors that influence the success of movies internationally. My study partially addresses this …

The Argentine Tango As A Discursive Instrument And Agent Of Social Empowerment: Buenos Aires, 1880-1955, Lorena Elizabeth Tabares

Open Access Theses & Dissertations

As an indisputable central element of Argentine popular culture, the tango constitutes much more than an artistic expression or a recreational activity. It is the manifestation of a collective ideology and idiosyncrasy. The development of the tango as a song of the people and social history between the 1880's and the first half of the 20th century, was not merely the result of a matter of identification but more importantly, the fact that it, in its `tridimensionality' comprised of music, dance and lyrics, offered the milieu to the existence of the people that identified with it. In other words, the …

Operational Code And Al-Ikhwan: An Assessment Of The Evolution Of The Muslim Brotherhood's Operational Code And Possible Public Diplomacy Options For The United States, Robert Kevin Thomson

Open Access Theses & Dissertations

The primary aim of this Thesis is to provide the reader with a firm understanding of the evolution of the Muslim Brotherhood's operational code from the early 2000s to 2013. Specifically, this research will address and analyze the evolution of the Brotherhood's political rhetoric from its historical context to the present. The Brotherhood's political rhetoric will be analyzed utilizing Operational Code Analysis. The secondary aim of this research is to provide a potential framework for policymakers and diplomats to utilize public diplomacy and strategic communication strategies to engage and constrain the influence of the Brotherhood in a globalized society. This …

Countering The Dreamer Narrative: Storytelling, Immigration Reform, And The Work Of 67 Sueños, Drew Schmenner

Master's Theses

Research question: How has the practice of storytelling been used in the current U.S. conflicts over immigration?

Telling an effective story is an essential part of a complex strategy to bring about social change, but storytelling as a part of collective action has not been extensively studied. For activists in the United States fighting for immigrant rights, especially the passage of the DREAM Act, storytelling has been an important tactic, but the nature of the narrative that was constructed has its drawbacks because it excluded some members of the immigrant community. In 2010, the Bay Area-based group 67 Sueños (“67 …

Is The White Collar Offender Privileged?, Samuel W. Buell

Duke Law Journal

Much public commentary has asserted or implied that the American criminal-justice system unjustly privileges individuals who commit crimes in corporations and financial markets. This Article demonstrates that this claim is not accurate—at least not in the ways commonly believed. Law and practice of sentencing, evidence, and criminal procedure cannot persuasively be described as privileging the white collar offender. Substantive criminal law makes charges in white collar cases easier to bring and harder to defend against than in other cases. Enforcement institutions, and the political economy in which they exist, include features that both shelter corporate offenders and heighten their exposure …

Mentor Preparation: A Qualitative Study Of Stem Master Teacher Professional Development, Heather Lynn Click-Cuellar

Open Access Theses & Dissertations

The No Child Left Behind Act of 2001 has required districts to staff all classrooms with highly qualified teachers. Yet, retaining certified teachers in the profession has been a national concern, especially among new teachers who leave at alarming rates within their first three years. This comes at a heavy cost to districts financially and in trying to maintain highly qualified status, but also to the continuity and effective education of students. Mentoring has been identified by many researchers as a plausible solution to reducing attrition rates for beginning teachers.

In this Dissertation, I conducted qualitative research to explore and …

The Contributions Of Leonard Bernstein And Frederick Fennell To The World Of Music, Ryan James Dore

Open Access Theses & Dissertations

Examination of the lives and contributions of Leonard Bernstein and Frederick Fennell to the world of music. Brief biography and comparison between their accomplishments, conducting, professional lives and education philosophies.