Digital Commons Network^™

Affinity Proteomics Within Rare Diseases: A Bio‐Nmd Study For Blood Biomarkers Of Muscular Dystrophies, Brucu Ayoglu, Amina Chaouch, Hans Lochmuller, Luisa Politano, Enrico Bertini, Sebahattin Cirak, +17 Additional Authors

Genomics and Precision Medicine Faculty Publications

Despite the recent progress in the broad‐scaled analysis of proteins in body fluids, there is still a lack in protein profiling approaches for biomarkers of rare diseases. Scarcity of samples is the main obstacle hindering attempts to apply discovery driven protein profiling in rare diseases. We addressed this challenge by combining samples collected within the BIO‐NMD consortium from four geographically dispersed clinical sites to identify protein markers associated with muscular dystrophy using an antibody bead array platform with 384 antibodies. Based on concordance in statistical significance and confirmatory results obtained from analysis of both serum and plasma, we identified eleven …

The Phenology Of Ticks And The Effects Of Long-Term Prescribed Burning On Tick Population Dynamics In Southwestern Georgia And Northwestern Florida, Elizabeth R. Gleim, L. Mike Conner, Roy D. Berghaus, Michael L. Levin, Galina E. Zemtsova, Michael J. Yabsley

Environmental Studies / Environmental Science Faculty Scholarship

Some tick populations have increased dramatically in the past several decades leading to an increase in the incidence and emergence of tick-borne diseases. Management strategies that can effectively reduce tick populations while better understanding regional tick phenology is needed. One promising management strategy is prescribed burning. However, the efficacy of prescribed burning as a mechanism for tick control is unclear because past studies have provided conflicting data, likely due to a failure of some studies to simulate operational management scenarios and/or account for other predictors of tick abundance. Therefore, our study was conducted to increase knowledge of tick population dynamics …

Abuse Awareness Training For Adults Relating To Sexual Misconduct And Sexual Harassment, Catholic Church. Archdiocese Of Santa Fe (N.M.)

Sexual Misconduct Policies

No abstract provided.

Antibiotic Prophylaxis And Reflux: Critical Review And Assessment, Bernarda Viteri Baquerizo, Craig A. Peters

Urology Faculty Publications

The use of continuous antibiotic prophylaxis (CAP) was critical in the evolution of vesicoureteral reflux (VUR) from a condition in which surgery was the standard of treatment to its becoming a medically managed condition. The efficacy of antibiotic prophylaxis in the management of VUR has been challenged in recent years, and significant confusion exists as to its clinical value. This review summarizes the critical factors in the history, use, and investigation of antibiotic prophylaxis in VUR. This review provides suggestions for assessing the potential clinical utility of prophylaxis.

Death Patterns During The 1918 Influenza Pandemic In Chile, Gerardo Chowell, Lone Simonsen, Jose Flores, Mark A. Miller, Cecile G. Viboud

Global Health Faculty Publications

Scarce information about the epidemiology of historical influenza pandemics in South America prevents complete understanding of pandemic patterns throughout the continent and across different climatic zones. To fill gaps with regard to spatiotemporal patterns of deaths associated with the 1918 influenza pandemic in Chile, we reviewed archival records. We found evidence that multiple pandemic waves at various times of the year and of varying intensities occurred during 1918-1921 and that influenza-related excess deaths peaked during July-August 1919. Pandemic-associated mortality rates were elevated for all age groups, including for adults >50 years of age; elevation from baseline was highest for young …

The Impact Of An Eu–Us Transatlantic Trade And Investment Partnership Agreement On Biofuel And Feedstock Markets, John C. Beghin, Jean-Christophe Bureau, Alexandre Gohin

Department of Agricultural Economics: Faculty Publications

We assess the impact of a potential TTIP bilateral free trade agreement on the EU and US bio-economies (feedstock, biofuels, by-products, and related competing crops) and major trade partners in these markets. The analysis develops a multi-market model that incorporates bilateral trade flows (US to EU, EU to US, and similarly with third countries) and is calibrated to OECD-FAO baseline for 2013–2022 to account for recent policy decisions. The major policy reforms from a TTIP involve tariff and TRQ liberalization and their direct contractionary impact on US sugar supply, EU biofuel production, and indirect negative effect on US HFCS production. …

Coagulopathy In Newborns With Hypoxic Ischemic Encephalopathy (Hie) Treated With Therapeutic Hypothermia: A Retrospective Case-Control Study, Katie R. Forman, Yaser A. Diab, Edward C.C. Wong, Stephen Baumgart, Naomi L. Luban, An Nguyen Massaro

Pediatrics Faculty Publications

Background

Newborns with hypoxic ischemic encephalopathy (HIE) are at risk for coagulopathy due to systemic oxygen deprivation. Additionally, therapeutic hypothermia (TH) slows enzymatic activity of the coagulation cascade, leading to constitutive prolongation of routinely assessed coagulation studies. The level of laboratory abnormality that predicts bleeding is unclear, leading to varying transfusion therapy practices.

Methods

HIE infants treated with TH between 2008–2012 were included in this retrospective study. Initial, minimum (min) and maximum (max) values of International Normalized Ratio (INR), activated partial thromboplastin time (aPTT), fibrinogen (Fib) and platelet (PLT) count (measured twice daily during TH) were collected. Bleeding was defined …

The Impact Of Polio Eradication On Routine Immunization And Primary Health Care: A Mixed-Methods Study, Svea Closser, Kelly Cox, Thomas M. Parris, R Matthew Landis, Judith Justice, Ranjani Gopinath, Kenneth Maes, Hailom Banteyerga Amaha, Ismaila Zango Mohammed, Rashid Jooma

Section of Neurosurgery

Background: After 2 decades of focused efforts to eradicate polio, the impact of eradication activities on health systems continues to be controversial. This study evaluated the impact of polio eradication activities on routine immunization (RI) and primary healthcare (PHC).
Methods: Quantitative analysis assessed the effects of polio eradication campaigns on RI and maternal healthcare coverage. A systematic qualitative analysis in 7 countries in South Asia and sub-Saharan Africa assessed impacts of polio eradication activities on key health system functions, using data from interviews, participant observation, and document review.
Results: Our quantitative analysis did not find compelling evidence of widespread and …

Redeeming Bond?, Alison Lacroix

Articles

No abstract provided.

Music, Personhood, And Eudaimonia: Implications For Educative And Ethical Music Education, David J. Elliott, Marissa Silverman

John J. Cali School of Music Scholarship and Creative Works

This paper proposes that educative and ethical music making and teaching, which is based on a praxial philosophy of music education (Elliott and Silverman, 2014), can be carried out in a variety of ways that create places and spaces, in schools and community settings, for a variety of human values or "goods" that include, but go beyond, making and listening to classical instrumental music, or any other kind of music, for "the music itself." One premise of this philosophical discussion is that music does not have one value; music has numerous values, depending on the ways in which it is …

November 2014, Pope Francis

Marian Thoughts of Pope Francis

No abstract provided.

Path Flow Estimator For Planning Applications In Small Communities, Seungkyu Rya, Anthony Chen, H. Michael Zhang, Will Recker

Graduate Student Publications

This paper presents an alternative planning framework to model and forecast network traffic for planning applications in small communities, where limited resources debilitate the development and applications of the conventional four-step travel demand forecasting model. The core idea is to use the path flow estimator (PFE) to estimate current and forecast future traffic demand while taking into account of various field and planning data as modeling constraints. Specifically, two versions of PFE are developed: a base year PFE for estimating the current network traffic conditions using field data and planning data, if available, and a future year PFE for predicting …

Symptom Burden And Healthcare Utilization In Pulmonary Arterial Hypertension, Catherina Anne Madani Phd

Dissertations

Background: Pulmonary arterial hypertension (PAH) is a rapidly progressive disease. There is currently no cure; thus treatment is aimed at prolonging survival, improving functional status (FS), and symptom mitigation. Symptom burden (SB) can impact quality of life (QOL), and lead to increased healthcare utilization. Palliative care (PC) has been associated with higher QOL, decreased depression, aggressive care, and mortality. The Institute of Medicine's (IOM) recent report supports earlier integration of PC for people living with serious illness. Detection of patients at high risk for heavy SB may help to identify patients who could benefit from earlier integration of PC into …

Patients With Advanced Lung Cancer: Quality Of Life And Perception Of Dyspnea, Barbara A. Roces Phd, Msn, Np, Rn

Dissertations

Background: Dyspnea perception can be defined as a multidimensional experience of breathing discomfort, influenced by physiological, psychological, social, and environmental factors, that includes secondary psychological and behavioral responses and cannot be defined only by physical objective abnormalities (Mularski et al., 2010). Dyspnea is the most common and distressing symptom in patients with advanced lung cancer and decreases one's quality of life (QOL) (Smith et al., 2001). Furthermore, dyspnea has been found to interfere with physical activities such as walking, work, and psychological activities such as disposition, taking pleasure in life, relationship with others, and sleep (Tanaka, Akechi, Okuyama, Nishiwaki, & …

Patient Care Technology And The Nurse-Patient Relationship, Belinda M. Toole Phd, Msn, Rn

Dissertations

Background: Technological devices are increasingly used in healthcare and their proliferation has providers questioning the impact on the patient-provider relationship. Technological device integration has been studied in the primary care setting, less extensively in the acute care setting. The impact of device use on the nurse-patient relationship in acute care setting required further study, particularly with nursing's history of holistic practice incorporating caring and presence. Objectives: The study purpose was to explore the patient's perceptions of nurse caring and presence when technological devices were used in care delivery in the acute care setting. Specific aims were: 1) to describe the …

5th Asian Preventive Cardiology And Cardiac Rehabilitation Conference Cum 9th Certificate Course In Cardiac Rehabilitation

Journal of the Hong Kong College of Cardiology

No abstract provided.

An Approach For Actions To Prevent Suicides On Commuter And Metro Rail Systems In The United States, Mti Report 12-33, Jan L. Botha, Marissa K. Neighbour, Satnam Kaur

Mineta Transportation Institute

The primary goals of this report are to discuss measures to prevent suicides on commuter and metro rail systems, and to outline an approach for suicide prevention on rail systems. Based on existing literature and analysis of data obtained from the Metrolink system in Southern California, it was found that most suicides occur near station platforms and near access points to the track. Suicides occurred most frequently when relatively more trains were in operation and in areas of high population density. There do not appear to be suicide “hot spots” (e.g., linked to mental hospitals in the proximity, etc.), based …

November 2014 News Releases, University Of Montana--Missoula. Office Of University Relations

University of Montana News Releases, 1928, 1956-present

No abstract provided.

Planning For Adaptation To Climate Change: Lessons From The Us National Wildlife Refuge System, Robert L. Fischman, Vicky J. Meretsky, Alexei Babko, Michael Kennedy, Lei Liu, Michelle Robinson

Articles by Maurer Faculty

US national wildlife refuges have recent, detailed management plans illustrating the state of planning for climate-change adaptation in protected areas. Discussion of and prescriptions for addressing climate change increased in refuge plans between 2005 and 2010 but decreased in 2011. The plans respond to some climate-change impacts on biodiversity and call for monitoring but with little clarity regarding how to act on monitoring results and scant attention to future changes in phenology and community composition. The threats posed by sea-level rise generated the best-developed plan prescriptions. Examples of excellent prescriptions provide models for future planning. Some decision-support tools, such as …

Dr. Darrell Krueger’S Remarks: 16th Presidential Inauguration At Winona State University, November 1, 2024, Darrell W. Krueger

President's Papers

These are the transcribed remarks of Dr. Darrell W. Krueger, a past president of Winona State University for the 16th Presidential Inauguration of Dr. Kenneth Janz at Winona State University on November 1, 2024.

Transcribed from the recording of the “Inauguration of Kenneth Janz: 16th President of Winona State University” by Allison Quam, Archives and Special Collections Librarian- Winona State University.

SOURCE: "Inauguration of Kenneth Janz: 16th President of Winona State University" (2024). President's Videos. 6. https://openriver.winona.edu/presidentsvideos/6

Calmodulin Enhances Ribbon Replenishment And Shapes Filtering Of Synaptic Transmission By Cone Photoreceptors., Matthew J. Van Hook, Caitlyn M. Parmelee, Minghui Chen, Karlene M. Cork, Carina Curto, Wallace B. Thoreson

Journal Articles: Pharmacology & Experimental Neuroscience

At the first synapse in the vertebrate visual pathway, light-evoked changes in photoreceptor membrane potential alter the rate of glutamate release onto second-order retinal neurons. This process depends on the synaptic ribbon, a specialized structure found at various sensory synapses, to provide a supply of primed vesicles for release. Calcium (Ca(2+)) accelerates the replenishment of vesicles at cone ribbon synapses, but the mechanisms underlying this acceleration and its functional implications for vision are unknown. We studied vesicle replenishment using paired whole-cell recordings of cones and postsynaptic neurons in tiger salamander retinas and found that it involves two kinetic mechanisms, the …

High School Athletes’ Perceptions Of Concussion, Theresa Miyashita, Eleni Diakogeorgiou, Brian Hellstrom, Nick Kuchwara, Erica Tafoya, Lori Young

All PTHMS Faculty Publications

Background: The perception high school athletes have regarding concussions may influence their injury-reporting behavior, and if their perceptions are based on incorrect or incomplete information, they may be at risk for subsequent head injuries.

Purpose: To determine whether the recent influx of concussion information has had a positive impact on high school athletes’ knowledge of concussions, to determine their perceptions regarding the severity of a concussion injury, and to determine whether receiving correct information will potentially alter their future reporting behavior.

Benchmarks 2014, November 21, The Rockefeller University

BenchMarks 2014

BenchMarks. Friday, November 21, 2014

The community newsletter of The Rockefeller University

BenchMarks is published monthly and is distributed on the campus of The Rockefeller University. It produced by the Office of Communications and Public Affairs

Tremblings, November 2014, Western Aspen Alliance

Tremblings

Aspen soil - The dynamic world below the surface

Helga Van Miegroet

We sometimes forget that the ecosystem services provided by forests are supported by the belowground component of the ecosystem—the soil. Soils, comprised of mineral material, biota, organic matter, water, and gasses represent a microcosm of hydrological, chemical, physical, and biological processes that underlie critical forest functions, such as the ability to hold and supply water and nutrients. As a manager, it is important to know how and to what extent ecosystem changes, whether natural or human-caused, have altered site quality or productive capacity, as it may inform future …

Pharmacy Student Perceptions: How Do They Change And What Does That Mean?, Erika Lynn Michalski

Dissertations

With healthcare moving rapidly toward interprofessional expectations, this study examined the perceptions of a particular population of students pursuing a degree in the healthcare field. Pharmacy students attending a free-standing pharmacy institution were interviewed over the course of the 2012 – 2013 academic year. Interviews were conducted before, during, and after the students engaged in collaborative coursework with students from a variety of health care majors attending a nearby institution. The results demonstrated the positive impact exposure to peer students pursuing degrees in health care fields can have. Results of the interview process highlighted the impact intentional interaction with a …

Hydrolyzed Tuna Meat By-Product Supplement For Juvenile Red Sea Bream, Pagrus Major, And Its Effect On Growth, Enzyme Activity, Plasma Parameters, And Apparent Nutrient Digestibility, Janice A. Ragaza, Roger Edward P. Mamauag, Shunsuke Koshio, Manabu Ishikawa, Saichiro Yokoyama

Biology Faculty Publications

A growth experiment was conducted on juvenile red sea bream, Pagrus major to investigate the effect of the inclusion in fish diets, of tuna meat by-product hydrolysate which was processed through enzymatic hydrolysis using a commercially available enzyme, derived from Bacillus subtilis. Six experimental diets were formulated in the experiment. Three diets contained 50, 150 and 250 g/kg of TPM-H (tuna meat by-product hydrolysate), and two diets with the unprocessed TPM (tuna meat by-product) at an inclusion level of 50 and 250 g/kg. A control diet was formulated without any addition of the test ingredients. Treatment diets were fed ad …

Stand With Sam: Missouri, Survivor Benefits, And Discrimination Against Same-Sex Couples, Lesley A. Hall

Missouri Law Review

In Glossip v. Missouri Department of Transportation and Highway Patrol Employees’ Retirement System, the Supreme Court of Missouri perpetuated these fears. The court refused to identify sexual orientation as a classification worthy of heightened or “intermediate” equal protection scrutiny, signaling to Missourians that homosexuality is still something to discount, fear, and hide. The holding also erroneously deprived Kelly Glossip of Corporal Engelhard’s survivor benefits after Engelhard, his partner of many years, was killed in the line of duty. This Note discusses the resolution of this case and analyzes why the court’s holding demonstrates a regressive step for gays and lesbians …

Table Of Contents - Issue 4

Missouri Law Review

Table of Contents - Issue 4

A Tiger With No Teeth: The Case For Fee Shifting In State Public Records Law, Heath Hooper, Charles N. Davis

Missouri Law Review

A federal lawsuit filed against the city of Columbia, Missouri, alleging police brutality seemed destined for headlines in 2010. At its core was an incident in which a routine traffic stop for a broken taillight erupted into a “fracas” in which police allegedly both tased and beat a man and threw a woman to the ground. A Columbia Daily Tribune reporter following the case filed a public records request for any documents concerning the incident. A police spokesperson contacted him days later to let him know the records were ready for pickup.

Legal Journalism Today: Change Or Die, Howard Mintz

Missouri Law Review

Several years ago, I was a guest speaker for a media and law class at San Jose State University, volunteering my expertise as a legal journalist with a couple decades under my belt of covering courts and law. As I went through my usual dialogue, describing some of the newfound challenges of being a journalist in this brave new digital world, one of the students piped in about Twitter, which at the time was an emerging phenomenon that I frankly considered a mind-numbing threat to intelligent reporting with the shelf life of the Pet Rock (an obsolete cultural reference that …