Digital Commons Network^™

Visualization Of Oxytocin Release That Mediates Paired Pulse Facilitation In Hypothalamic Pathways To Brainstem Autonomic Neurons, Ramon A. Pinol, Heather Jameson, Anastas Popratiloff, Norman H. Lee, David Mendelowitz

Pharmacology and Physiology Faculty Publications

Recent work has shown that oxytocin is involved in more than lactation and uterine contraction. The paraventricular nucleus of the hypothalamus (PVN) contains neuroendocrine neurons that control the release of hormones, including vasopressin and oxytocin. Other populations of PVN neurons do not release hormones, but rather project to and release neurotransmitters onto other neurons in the CNS involved in fluid retention, thermoregulation, sexual behavior and responses to stress. Activation of oxytocin receptors can be cardioprotective and reduces the adverse cardiovascular consequences of anxiety and stress, yet how oxytocin can affect heart rate and cardiac function is unknown. While anatomical work …

Medical Education Digest, Vol. 16 No. 6 (November/December 2014), Nova Southeastern University

Medical Education Digest

No abstract provided.

Evaluating Gps Effectiveness For Natural Resource Professionals: Integrating Undergraduate Students In The Decision-Making Process, Daniel Unger, I-Kuai Hung, Yanli Zhang, David Kulhavy

Faculty Publications

Undergraduate students pursuing a Bachelor of Science in Forestry (BSF) degree at Stephen F. Austin State University (SFA) attend an intensive 6-week residential hands-on instruction in applied field methods. For students pursuing the BSF degree knowing the exact location of a forestland is crucial to the understanding and proper management of any related natural resource. The intensive 6-week instruction includes teaching how to use the Global Positioning System (GPS) to accurately record the spatial location of an earth’s surface feature. After receiving hands-on instructions during the summer of 2014, students were taken to the field to collect real-world locations. Students …

Generating Caenorhabditis Elegans Unc-33 Antigens To Be Used For The Synthesis Of Polyclonal Antibodies, Matt Abbott, Jacob Fuller, Mason Howe, Michael Caniglia, Andrea Holgado

SWOSU Journal of Undergraduate Research

UNC-33 and its human homolog, CRMP2 (Collapsin Response Mediator Protein-2), have been demonstrated to be involved in neurodevelopment as well as neurodegenerative disorders, primarily Alzheimer’s Disease. However, the physiology and interactions of these associations are vague. In order to further understand UNC-33/CRMP2, our group decided to use molecular biology and work toward the production of polyclonal antibodies specific to C. elegans UNC-33. To do this, we utilized the GST tag Gene Fusion System and produced two antigens- UNC-33 amino acid 48 to 212 and UNC-33 amino acid 48 to131 (UNC-3348-212 and UNC-3348-131). During this process, parameters were developed for the …

Multidisciplinary Group Clinic Appointments: The Self-Management And Care Of Heart Failure (Smac-Hf) Trial, Carol A. Smith, Ubolrat Piamjariyakul, Jo A. Wick, John A. Spertus, Christy Russell, Kathleen M. Dalton, Andrea Elyachar, James L. Vacek, Katherine M. Reeder, Niaman Nazir, Edward F. Ellerbeck

College of Nursing Faculty Publications

Background—This trial tested the effects of multidisciplinary group clinic appointments on the primary outcome of time to first heart failure (HF) rehospitalization or death.

Methods and Results—HF patients (n=198) were randomly assigned to standard care or standard care plus multidisciplinary group clinics. The group intervention consisted of 4 weekly clinic appointments and 1 booster clinic at month 6, where multidisciplinary professionals engaged patients in HF self-management skills. Data were collected prospectively for 12 months beginning after completion of the first 4 group clinic appointments (2 months post randomization). The intervention was associated with greater adherence to recommended vasodilators …

Faculty Perspectives On The Inclusion Of Spirituality Topics In Nonsectarian Leadership And Management Education Programs, Peter E. Williams, Stuart Allen

School of Educational Leadership

The purpose of this study was to explore faculty views on the inclusion of spiritual topics in graduate leadership and management programs, focusing on faculty experiences, perceived benefits and challenges, and teaching methods and principles in use. We interviewed twelve faculty members in leadership or management programs from eleven nonsectarian universities. Participants discussed eight benefits including the opportunity for whole person growth and skill development that would benefit leaders in a global workplace. Eight barriers to such inclusion were identified such as proselytizing and the misuse of power. The sampled instructors also made some suggestions for how to include spirituality …

New Oral Anticoagulants For The Treatment Of Venous Thromboembolism: Understanding Differences And Similarities., Paul P. Dobesh, John Fanikos

Journal Articles: Pharmacy Practice

Venous thromboembolism (VTE) is a major cause of morbidity, mortality, and healthcare expenditure. In the United States, approximately 0.1 % of the population experiences an initial VTE event each year. Anticoagulation therapy is the cornerstone of acute VTE treatment and for prevention of recurrent VTE events. Conventional anticoagulants, including heparin, low-molecular-weight heparins, fondaparinux, and vitamin K antagonists are widely used but have limitations. Newer oral anticoagulant agents, including direct thrombin inhibitors (e.g., dabigatran etexilate) and direct factor Xa inhibitors (e.g., rivaroxaban, apixaban, and edoxaban) have been developed to attempt to overcome some of the limitations of conventional anticoagulant therapy. These …

Keynoter, November/December 2014, Boise State University Association Of Office Professionals

Boise State University Association of Office Professionals - Keynoter

President's Message

BSUAOP Officers

Standing Committees

Mind Tools

Did You Know?

BSUAOP Member Representatives

BSUAOP Membership - What's in It For You?

The Christmas Cards Extraordinaire Stampin’ Up!

Instant Notification

Solving the Only Problem You've Ever Had

BSUAOP Luncheon & Annual Holiday Auction

Looking Back….Waaay Back!

Recycling Program

Are There Benefits to Being an Affiliate of NAEOP and IAEOP?

University Health Services for Boise State Employees

I Know Something Good About You

BSUAOP Board Meetings...In a Nutshell

One Sky International Awareness Event

BSUAOP Purpose and Code of Ethics

BSUAOP Membership List

PSP Endorsements

Professional Standards Program

Boise State University Association …

Checkup, Lehigh Valley Health Network

Checkup

No abstract provided.

Miracles, Science, Or Both?, Deborah Tyokighir

Student Work

What is a miracle? What is science? Do miracles cease to be exciting when a scientific explanation is found? Does an event, explainable by science, undermine the power of the Divine? This work investigates the tension that we have created between divine action and natural law, using the medieval Eucharist experience and related scientific findings as an example of this tension.

Progress Notes, Lehigh Valley Health Network

Progress Notes

No abstract provided.

Scholarworks Statistics - November 2014, Scholarworks

ScholarWorks Reports

For the month of November 2014, ScholarWorks recorded a total of 30,878 full-text downloads and 13,404 page views.

Communicator, Nov. 2014, San Jose State University, Department Of Kinesiology

Communicator (Kinesiology)

Volume 27, Issue 1

Fostering Reflective Insight In Graduate Speech-Language Pathology Students Using Lonergan’S Generalized Empirical Method., Theresa E. Bartolotta

Praxis Presentations

Lonergan’s Theory of Cognition was implemented in a graduate course in speech-language pathology. Students were introduced to the Generalized Empirical Method as a way to: •develop reflective practice •make informed clinical decisions •increase awareness of critical thinking processes.

Social Desire Paths: A New Theoretical Concept To Increase The Usability Of Social Science Research In Society, Laura Nichols

Sociology

Social scientists are well-trained to observe and chart social trends, but less experienced at presenting scientific findings in formats that can inform social change work. In this article, I propose a new theoretical concept that provides a mechanism by which social science research can be more effectively applied for proactive policy, organizational, and program development. The approach is to use the metaphor of “desire paths” from landscape architecture to show how social scientists can identify and analyze social desire paths that appear on the social structural landscape. Social desire paths usually emerge because existing formal structures do not meet individual …

Strengthening Neglected Tropical Disease Research Through Enhancing Research-Site Capacity: An Evaluation Of A Novel Web Application To Facilitate Research Collections, Tanzin Furtado, Samuel Franzen, Francois Van Loggerenberg, Gwenaelle Carn, Shannon Grahek, Megan Mcbride, Maureen Power, Barbara Savarese, Margaret Ann Snowden, Gwynn Stevens, Almarie Uys, Trudie Lang

Microbiology, Immunology, and Tropical Medicine Faculty Publications

No abstract provided.

The Translational Biology Of Remyelination: Past, Present, And Future, Robin J.M. Franklin, Vittorio Gallo

Pediatrics Faculty Publications

Amongst neurological diseases, multiple sclerosis (MS) presents an attractive target for regenerative medicine. This is because the primary pathology, the loss of myelin-forming oligodendrocytes, can be followed by a spontaneous and efficient regenerative process called remyelination. While cell transplantation approaches have been explored as a means of replacing lost oligodendrocytes, more recently therapeutic approaches that target the endogenous regenerative process have been favored. This is in large part due to our increasing understanding of (1) the cell types within the adult brain that are able to generate new oligodendrocytes, (2) the mechanisms and pathways by which this achieved, and (3) …

Vitamin A, Vitamin E, Iron And Zinc Status In A Cohort Of Hiv-Infected Mothers And Their Uninfected Infants, Jacqueline Pontes Monteiro, Maria Leticia Santos Cruz, Marisa Marcia Mussi-Pinhata, Roberta Garcia Salomao, Alceu Jordao Junior, Jennifer S. Read, Jose Henrique Da Silva Pilotto, Rachel Ann Cohen, Sonia Karolina Stoszek, George Kelly Siberry

Pediatrics Faculty Publications

Introduction

We hypothesized that nutritional deficiency would be common in a cohort of postpartum, human immunodeficiency virus (HIV)-infected women and their infants.

Methods

Weight and height, as well as blood concentrations of retinol, α-tocopherol, ferritin, hemoglobin, and zinc, were measured in mothers after delivery and in their infants at birth and at 6-12 weeks and six months of age. Retinol and α-tocopherol levels were quantified by high performance liquid chromatography, and zinc levels were measured by atomic absorption spectrophotometry. The maternal body mass index during pregnancy was adjusted for gestational age (adjBMI).

Results

Among the 97 women 19.6% were underweight. …

Wright State University Women's Basketball Media Guide 2014-2015, Wright State University Athletics

Athletics Publications

A media guide for Wright State University's 2014-2015 Women's Basketball team. This guide includes photographs, player stats, game results, and records.

Research Digest Number 10: Parents And Teachers: Working Together To Foster Children’S Learning, Kate Perkins, Pat Knight, Marion Meiers

Research Digest

This edition of the Research Digest focuses primarily on parent-teacher collaboration, considering what research can tell us about:

• why parental engagement is important
• key features of effective collaborations
• critical challenges and issues that teachers and parents may face
• strategies that have helped teachers and parents build effective relationships

Some examples of activities undertaken as part of whole-school programs are also included. These illustrate the kind of scaffolding that helps teachers, parents and children establish the foundations for effective interactions.

The Digest draws on searches of data bases and bibliographic resources including the Australian Education Index, Education Resources Information Center (ERIC), …

Geophysical Survey Of Wisconsin Burial Site Ou-0122: Outagamie County Insane Asylum Cemetery, Peter N. Peregrine

Archaeological Reports

No abstract provided.

Does The Worsening Galactic Cosmic Radiation Environment Observed By Crater Preclude Future Manned Deep Space Exploration?, Nathan A. Schwadron, J. B. Blake, Anthony Case, Colin J. Joyce, Justin Kasper, J. E. Mazur, N. Petro, M. Quinn, Jamie A. Porter, Charles W. Smith, Sonya S. Smith, Harlan E. Spence, Lawrence W. Townsend, R. Turner, Jody K. Wilson, Cary Zeitlin

Physics & Astronomy

Abstract

The Sun and its solar wind are currently exhibiting extremely low densities and magnetic field strengths, representing states that have never been observed during the space age. The highly abnormal solar activity between cycles 23 and 24 has caused the longest solar minimum in over 80 years and continues into the unusually small solar maximum of cycle 24. As a result of the remarkably weak solar activity, we have also observed the highest fluxes of galactic cosmic rays in the space age and relatively small solar energetic particle events. We use observations from the Cosmic Ray Telescope for the …

Molecular Characterization Of Protease Activity In Serratia Sp. Strain Scbi And Its Importance In Cytotoxicity And Virulence, Lauren M. Petersen, Louis S. Tisa

New Hampshire Agricultural Experiment Station Publications

A newly recognized Serratia species, termed South African Caenorhabditis briggsae isolate (SCBI), is both a mutualist of the nematode Caenorhabditis briggsae KT0001 and a pathogen of lepidopteran insects. Serratia sp. strain SCBI displays high proteolytic activity, and because secreted proteases are known virulence factors for many pathogens, the purpose of this study was to identify genes essential for extracellular protease activity in Serratia sp. strain SCBI and to determine what role proteases play in insect pathogenesis and cytotoxicity. A bank of 2,100 transposon mutants was generated, and six SCBI mutants with defective proteolytic activity were identified. These mutants were also …

Potential Immunotherapy For Prostate Cancer: Recombinant Bacille Calmette-Guerin Expressing Prostate Specific Molecules, Christine Zeoli-Costa, Henry P. Godfrey, Michael Iatropoulos, Polly Gregor, Abraham Mittelman, Jan Geliebter

NYMC Faculty Publications

Purpose: The emergence of prostate cancer as a major health issue and the absence of curative treatment for metastatic disease requires the development of new treatment modalities. Prostate specific antigen (PSA) and prostate-specific membrane antigen (PSMA) are possible targets for prostate cancer immunotherapy. We have previously shown that PSA and PSMA can be expressed in recombinant bacille Calmette-Guérin (BCG) strains. Methods: The in vivo immunogenicity of the prostate-specific proteins produced by this recombinant BCG strain were examined by detection of specific antibody responses and delayed-type hypersensitivity (DTH) responses in mice vaccinated with these strains. These immune responses were compared with …

Psychosocial Factors In Sports Injury Rehabilitation And Return To Play, Leslie W. Podlog, John Heil, Stefanie Podlog (Nee Schulte)

Athletic Training Collection

This article discusses the principles and practices that guide psychological intervention with injury, and encourages a psychological approach to injury for clinicians. Part 1 reviews the research literature, and serves as a foundation for the review of clinical practices in part 2. Examination of the research literature highlights 4 areas: (1) psychological factors influencing rehabilitation, (2) social factors affecting rehabilitation, (3) performance concerns among returning athletes, and (4) tools/inventories for assessing psychological readiness to return. A synopsis of an injury intervention plan is provided, and the influence of pain and fear in the rehabilitation process is described.

Intercultural Interactions Outside The Classroom: Narratives On A U.S. Campus, Xinran Lehto, Liping A. Cai, Xiaoxiao Fu, Yi Chen

Rosen Faculty Scholarship and Creative Works

This study provides a picture of the interactional experiences between domestic and international undergraduate students outside the classroom on a US campus. Based on 9 focus group sessions, 8 distinctive themes emerged as a result. The study revealed some similarities but many differences between domestic and international students, illuminating the lack of and barriers to intercultural learning. The findings highlight the challenges and opportunities currently faced on US campuses, thereby making a timely contribution to efforts at developing students’ readiness to be successful in a global and multicultural environment.

Method For Investigating Nursing Behaviors Related To Isolation Care., Elizabeth L. Beam, Shawn G. Gibbs, Angela L. Hewlett, Peter C. Iwen, Suzanne L. Nuss, Philip W. Smith

Journal Articles: College of Nursing

BACKGROUND: Although an emphasis has been placed on protecting patients by improving health care worker compliance with infection control techniques, challenges associated with patient isolation do exist. To address these issues, a more consistent mechanism to evaluate specific clinical behaviors safely is needed.

METHODS: The research method described in this study used a high fidelity simulation using a live standardized patient recorded by small cameras. Immediately after the simulation experience, nurses were asked to view and comment on their performance. A demographic survey and a video recorded physical evaluation provided participant description. A questionnaire component 1 month after the simulation …

November Post 6, Breeanne Martin

Digital Folklore Project 2014

No abstract provided.

November Post 1, Liz Leavitt

Digital Folklore Project 2014

No abstract provided.

Discovery Of Thienoquinolone Derivatives As Selective And Atp Non-Competitive Cdk5/P25 Inhibitors By Structure-Based Virtual Screening, Arindam Chatterjee, Stephen J. Cutler, Robert J. Doerksen, Ikhlas A. Khan, John S. Williamson

Office for Research Publications and Presentations

Calpain mediated cleavage of CDK5 natural precursor p35 causes a stable complex formation of CDK5/p25, which leads to hyperphosphorylation of tau. Thus inhibition of this complex is a viable target for numerous acute and chronic neurodegenerative diseases involving tau protein, including Alzheimer’s disease. Since CDK5 has the highest sequence homology with its mitotic counterpart CDK2, our primary goal was to design selective CDK5/p25 inhibitors targeting neurodegeneration. A novel structure-based virtual screening protocol comprised of e-pharmacophore models and virtual screening workflow was used to identify nine compounds from a commercial database containing 2.84 million compounds. An ATP non-competitive and selective thieno[3,2- …