Digital Commons Network^™

The Mechanism For Inhibition Of Vibrio Cholerae Virulence Gene Expression By Bile And Its Fatty Acid Components, Sarah Plecha

Wayne State University Dissertations

Vibrio cholerae is responsible for the diarrheal disease cholera by producing two major virulence factors: cholera toxin (CT) and toxin-coregulated pilus (TCP). During infection, V. cholerae downregulates its motility genes, which are actively expressed in the environment, and upregulates its virulence genes, which are inactive in the environment. Virulence gene transcription is regulated by the major transcriptional activator, ToxT. ToxT is regulated, in part, by host signals, which in turn, make ToxT active or inactive in respect to virulence gene expression. Host signals include temperature and pH as well as the chemical molecules bicarbonate and bile, which are positive and …

Cervical Remodeling/Ripening At Term And Preterm Delivery: The Same Mechanism Initiated By Different Mediators And Different Effector Cells, Juan Miguel Gonzalez Velez

Wayne State University Dissertations

Premature cervical remodeling/ripening is believed to contribute to preterm delivery (PTD), the leading cause of perinatal morbidity and mortality. Despite considerable research, the causes of term and PTD remain unclear, and there is no effective treatment for PTD. We tested the hypothesis that complement activation plays a role in cervical remodeling and PTD. We studied cervical remodeling at term.

We studied two mouse models of inflammation-induced PTD. The first model was induced by vaginal administration of lipopolysaccharide (LPS)and the second one by administration of progesterone antagonist RU486. Increased cervical C3 deposition and macrophage infiltration and increased serum C3adesArg and C5adesArg …

An Exploration Of Emotional Intelligence And Its Relationship To Higher Education Effective Leadership Practices Of Leaders In A Community College Environment, Vicki Golden

Wayne State University Dissertations

ABSTRACT

AN EXPLORATION OF EMOTIVIONAL INTELLIGENCE AND ITS RELATIONSHIP TO HIGHER EDUCATION EFFECTIVE LEADERSHIP PRACTICES OF LEADERS IN A COMMUNITY COLLEGE ENVIRONMENT

By

VICKI A. GOLDEN

November, 2014

Advisor: Dr. Ingrid Guerra-Lopez

Major: Performance Improvement

Degree: Doctor of Philosophy

Emotional intelligence (EI) has been shown to directly relate to the enhancement of successful leadership attributes (Giesecke, 2008a, 2008b; Goleman, 2011a; Kruml & Yockey, 2010; Nadler, 2011; Riggio, 2010) and effective leaders have been found to possess significant degrees of EI in business settings (Lykins, 2011; Allen, Shankman, & Miguel, 2012; Rehman, 2011)). Although the positive effects of EI on leadership …

Development And Human Performance Evaluation Of Control Modes Of An Exo-Skeletal Assistive Robotic Arm (Esara), Umer Khalid

Wayne State University Dissertations

This research was conducted to assist with functional tasks for a targeted group of individuals with spinal cord injury (SCI); with C5 to C7 level of injury relating to upper extremity movement. The specific population was selected as the existing technology was either too expensive, too bulky or was unable to address their needs in regards to upper extremity mobility. In addition, no platforms allowed multimodal control options for customization or provided a methodology for this crucial evaluation. The motivation of this research was to provide a methodology for selecting the appropriate control of an assistive device based on the …

Characterization Of Initial Iron Binding Location And The Structure/Iron Binding Site On S.Cerevisiae Isu And On D.Melanogaster Frataxin, Andria V. Rodrigues

Wayne State University Dissertations

Iron-induced free radical damage has been implicated in the pathology of diseases of iron overload such as Friedreich's Ataxia, a genetic disorder characterized by an accumulation of iron in actively metabolizing tissues ultimately leading to cardio- and neuro- degeneration and cell death. It is caused by an inability to synthesize the mitochondrial protein, frataxin. Frataxin has been shown by numerous groups to be a part of the iron-sulfur cluster (ISC) multicomplex, where it functions in the capacity of a potential iron provider and an allosteric modulator of both the cysteine desulfurase and scaffold protein ISU. My research has been focused …

A Designed Research Study Examining The Impact Of Using A Motivational Model For Mastering The Crash Cart, Debra Amaro

Wayne State University Dissertations

Abstract

This research study examined the effects of strategically designed crash cart training using Keller's motivational design model ARCS (Keller, 2010) for novice nurses. The purpose of this mixed methods design-based research study was to determine the motivational levels of novice/beginner nurses in the work environment and seek out whether or not motivational designed instruction for the crash cart will significantly impact their mastery of the crash cart. Quantitative and qualitative data were collected within iterations of the study to determine the motivational levels of novice nurses pertaining to crash cart training. Motivational levels were determined utilizing Keller's (2010), "Course …

Table Of Contents - Cardozo Journal Of Conflict Resolution, Vol. 15, Iss. 2

Cardozo Journal of Conflict Resolution

No abstract provided.

Symposium Issue Introduction And Dedication, Shawna Benston

Cardozo Journal of Conflict Resolution

The 2013 Jed D. Melnick Annual Symposium, which took place on November 18th, 2013, was entitled "Bioethics, Healthcare Policy, and Alternative Dispute Resolution in the Age of Obamacare." Scholars and practitioners of bioethics alternative dispute resolution came together to discuss the likely impact of a healthcare overhaul born of an ethical challenge: to achieve the greatest good for the greatest number while continuing to honor the value of the individual. Collectively, the Symposium participants anticipated the particular importance of mediation and bioethical debate within the complex health-delivery system that has been drafted under this biomedical imperative.

The Growing Power Of Healthcare Ethics Committees Heightens Due Process Concerns, Thaddeus Mason Pope

Cardozo Journal of Conflict Resolution

Complex ethical situations, such as end-of-life medical treatment disputes, occur on a regular basis in healthcare settings. Healthcare ethics committees (HECs) have been a leading dispute resolution forum for many of these conflicts. But while the function of HECs has evolved from mediation to adjudication, the form of HECs has not evolved to adapt to this expanded and more consequential function.

Bioethics Mediation At The End Of Life: Opportunities And Limitations, Ellen Waldman

Cardozo Journal of Conflict Resolution

Medical advances in a wide variety of areas are helping more and more elderly people live longer. When hearts, lungs and kidneys failed in the past, death came swiftly and without discussion. Today, failing organs mobilize a sophisticated arsenal of medical technology designed to keep death at bay.

Managing Conflict In Clinical Health Care With Diminished Reliance On Third Party Intervention: Forging An Ethical And Legal Mandate For Effective Physician-Patient Communication, Edward J. Bergman

Cardozo Journal of Conflict Resolution

The world of clinical medicine is rife with conflict among caregivers, patients and their surrogates. This should not surprise given medicine's scientific, psychological, and language complexities, high stakes, fragmentation of care, multiplicity of players, time constraints, institutional politics, cultural differences, competing philosophies and economic dimensions. "Hospital life with its byzantine array of moving parts layered atop the unpredictable rhythms of illness is a permanent state of flux."

Bioethics Mediation & The End Of Clinical Ethics As We Know It, Autumn Fiester

Cardozo Journal of Conflict Resolution

In this Article, I will not only argue that bioethics mediation is a superior approach for resolving ethics conflicts, but I will also defend the controversial position that it is the only ethically justifiable method for resolving values-based conflicts in a pluralistic society. Although it has so far been relegated to the status of mere handmaiden to conventional consultation, bioethics mediation-as its detractors have surmised-has the potential to end clinical ethics consultation as we know it.

"Cut The Dog In Half": Resolving Animal Law Disputes Through The Use Of Alternative Dispute Resolution, Michael Ploudre Kaiser

Cardozo Journal of Conflict Resolution

In this article, I discuss ADR within the context of three types of animal law issues. In Part I, I discuss animal custody disputes, which I have found to be very well-suited to resolution by means of mediation. In Part II, I discuss the debate surrounding laboratory testing on animals and the reasons why several current approaches to this issue are insufficient and wasteful of resources. I outline how mediation has the potential to bridge differences and find at least short-term workable resolutions to a highly charged issue, which in turn may lead to longer-term resolutions. Lastly, in Part III, …

Chapter 9 Bankruptcy In California: The Efficacy Of Mandating Alternative Dispute Resolution In Municipal Bankruptcy Filings, Michael Galen

Cardozo Journal of Conflict Resolution

The subject of this Note is of importance to ADR practitioners: the incorporation of ADR into a new state law can mitigate a heated legal struggle involving state and federal law, while balancing the competing interests of powerful parties like local governments and large unions. This subject demonstrates the efficacy of ADR as applicable to bankruptcy law, a realm with which many ADR practitioners may be unfamiliar. This Note's case study focuses solely on California law and cases because California stands alone in its approach of mandating ADR as a precondition to a municipal bankruptcy filing. Since all states have …

The Sec Adds A New Weapon: How Does The New Admission Requirement Change The Landscape?, Paul Radvany

Cardozo Journal of Conflict Resolution

This Article will examine the SEC's revised settlement policy in the aftermath of Judge Rakoff's concerns about the SEC's longstanding "no admit, no deny" policy. In order to determine the import of the SEC's new settlement policy on the conduct of companies, as well as ongoing investigations and cases, this Article will also include analysis from lawyers who have advised their clients on the SEC's policy change.

Part II provides an overview of the SEC and its Enforcement Division, and describes the SEC's prosecutorial discretion. Part III examines Judge Rakoff's decisions in SEC v. Bank of Am. Corp.1 4 and …

Informed Consent In Mediation: Promoting Pro Se Parties' Informed Settlement Choice While Honoring The Mediator's Ethical Duties, Michael T. Colatrella Jr.

Cardozo Journal of Conflict Resolution

In explaining the proper role of informed consent in mediation, this Article will proceed as follows: Part II will examine mediation's core ethical values of self-determination, impartiality and promoting a quality process. Part III will explore the meaning and origins of the informed consent doctrine; and, in Part IV, analyze the application of informed consent policies and principles to mediation in the light of mediation's core ethical values. Part V will explore ways that mediators can promote informed outcome consent within the existing ethical framework and recommend legislative reform that will help clarify the mediator's proper role of promoting fair …

Status And Contract In An Emerging Democracy: The Evolution Of Dispute Resolution In Ghana, Paul F. Kirgis

Cardozo Journal of Conflict Resolution

Ghana is one of the developing world's success stories. The first sub-Saharan colony to gain independence, it is a stable democracy experiencing sustained economic growth. Yet as Ghana reaches for the material gains of participation in modern commercial life, its dual legal systems-the system of customary adjudication by traditional authorities and the formal court systemhave come under increasing pressure. New legal developments have truncated the authority of traditional decision-makers, while an overburdened court system lacks the resources to fill the resulting adjudicative gaps. To solve the problem, Ghana is now experimenting with a system of quasi-public dispute resolution, including contractual …

Brazil's Legacy Of International Parental Child Abduction: Mediation Under The Hague Abduction Convention As A Solution, Paula Shulman

Cardozo Journal of Conflict Resolution

This Note argues that Brazil's failures to comply with the commands of the Hague Convention, to expeditiously return children abducted by a parent from their habitual residence to Brazil, can be remedied with the adoption of a new mediation model in lieu of its current system. This new mediation protocol can be modeled on those adopted in the United Kingdom and Germany. Section II of this Note provides a history of IPCA and an analysis of the problems unresolved or springing from the Hague Convention. Section III examines Brazil's accession to the Hague Convention, the Brazilian Central Authority, the body …

Frcp 26 Vs. Fre 408: Why Settlement Negotiations Should Be Privileged Against Third-Party Discovery, Andrew Sher

Cardozo Journal of Conflict Resolution

This Note proposes that courts should recognize a settlementnegotiation privilege because it will incentivize parties to settle. Settling disputes is beneficial to the judicial system as it is more efficient and effective at resolving disputes than trying cases. Recognizing a settlement-negotiation privilege will increase the number of settlements by avoiding the free-rider problem that the Federal Circuit's approach in In re MSTG will create. Similarly, creating a settlement-negotiation privilege will avoid the uncertainty caused by not recognizing a privilege or requiring heightened standards for discovery. The confidentiality and certainty of a settlement-negotiation privilege will encourage parties to settle as well …

Slowing Antibiotic Resistance By Decreasing Antibiotic Use In Animals, Jennifer Nomura

Minnesota Journal of Law, Science & Technology

No abstract provided.

The Fight Against Oppression In The Digital Age: Restructuring Minnesota’S Cyberbullying Law To Get With The Battle, Bryan Morben

Minnesota Journal of Law, Science & Technology

No abstract provided.

Italian-American Literature And Working-Class Culture, Fred L. Gardaphé

Publications and Research

No abstract provided.

Development Of A Preliminary Scale Of Counterproductive Experiences In Supervision : Attitudes Of Clinical Psychology Doctoral Students, Nina Grayson

Theses and Dissertations

Clinical supervision is pivotal to the assurance of client welfare and in the development of clinical competency in the supervisee. In the process of guiding the professional and clinical development of supervisees, the supervisor monitors the provision of ethical and appropriate psychological care in order to promote the most successful clinical outcome for the client (Falender & Shafrankske, 2004). However, there may be events or experiences that can lead to negative outcomes. Any event or experience that hinders the supervisee's exercise and development of clinical competence, potentially endangers the welfare of the client, and contributes to a poor experience of …

Ileadership: The Leadership Style Of Steve Jobs, Christopher J. Valentine

Theses and Dissertations

In a technology-driven society, the global hunger for innovative products has put increased pressure on organizations to think differently. The pressure from shareholders on management to drive innovation and deliver financial results has forced leaders to adapt and look for new solutions to meet this demand. The solutions for which organizations are searching may reside in a new form of leadership required to achieve this expectation of performance. The purpose of this dissertation was to discover what leadership characteristics are required to achieve a high-performance technology organization. The primary goal was to review and decode archival scholarly and contemporary literature …

Characterization Of Sugar Diversity In Floral And Extra-Floral Nectar From The Coastal Coral Tree (Erythrina Caffra Thunb.) In Southern California, Victor D. Carmona-Galindo, Kenny Morales, Renee Maser, Julius Doyle, Mera Gobrial

Biology Faculty Works

The Coastal Coral Tree (Erythrina caffra Thunb.) produces floral nectar (FN) that serves to attract pollinating insects, but also secretes nectar from extra-floral (EFN) glands that serves to at-tract predatory insects, such as ants. While stu-dies on myrmecophytes (i.e. specialized plants that attract and interact with ants) have primarily focused on interspecific evaluations of EFN chemistry, the Coastal Coral tree offers an op-portunity to contrast intraspecific nectar chemi-stry with differing evolutionary and ecological functions. We hypothesized that the richness of (molecular) sugar species, relative concentra-tions, and diversity of sugars in FN and foliar EFN would diverge due to differences in …

Widespread Movement Of Invasive Cattle Fever Ticks (Rhipicephalus Microplus) In Southern Texas Leads To Shared Local Infestations On Cattle And Deer, Joseph D. Busch, Nathan E. Stone, Roxanne Nottingham, Ana Araya-Anchetta, Jillian Lewis, Christian Hochhalter, John R. Giles, Jeffrey Gruendike, Jeanne Freeman, Greta Buckmeier, Deanna Bodine, Roberta Duhaime, Robert J. Miller, Ronald B. Davey, Pia U. Olafson, Glen A. Scoles, David M. Wagner

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Background: Rhipicephalus (Boophilus) microplus is a highly-invasive tick that transmits the cattle parasites (Babesia bovis and B. bigemina) that cause cattle fever. R. microplus and Babesia are endemic in Mexico and ticks persist in the United States inside a narrow tick eradication quarantine area (TEQA) along the Rio Grande. This containment area is threatened by unregulated movements of illegal cattle and wildlife like white-tailed deer (WTD; Odocoileus virginianus).

Methods: Using 11 microsatellite loci we genotyped 1,247 R. microplus from 63 Texas collections, including outbreak infestations from outside the TEQA. We used population genetic analyses to …

Inter-Relationships Of Cotton Plant Height, Canopy Width, Ground Coverand Plant Nitrogen Status Indicators, F. M. Muharam, K. F. Bronson, S. J. Maas, G. L. Ritchie

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Petiole-NO₃, leaf N and chlorophyll (SPAD) meter readings are good in-season indicators of the N statusof the uppermost part of cotton (Gossypium hirsutum L.) plants. Petiole-NO₃, particularly is widely used inthe USA as an in-season plant N test that guides N fertilizer recommendations in cotton. However, theseN status indicators do not take account of plant biomass, canopy width or percent cover. The objectives ofthis study were to assess the effect of N fertilizer rates on the commonly used indicators of plant N status;leaf N, petiole sap NO₃and chlorophyll meter (SPAD) readings and …

Classification Of The Waxy Condition Of Durum Wheat By Near Infrared Reflectance Spectroscopy Using Wavelets And A Genetic Algorithm, Barry K. Lavine, Nikhil Mirjankar, Stephen Delwiche

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Near infrared (NIR) reflectance spectroscopy has been applied to the problem of differentiating four genotypes of durum wheat: ‘waxy’, Wx A1 null null, wx-B1 null and wild type. The test data consisted of 95 NIR reflectance spectra of wheat samples obtained from a USDA-ARSwheat breeding program. A two-step procedure for pattern recognition analysis of NIR spectral data wasemployed. First, thewavelet packet transform [14,15] was applied to the NIR reflectance data usingwavelet filters at different scales to extract and separate low-frequency signal components from high frequency noise components. By applying these filters, each reflectance spectrum was decomposed into wavelet coefficients that …

Whole Genome Sequencing And Phylogenetic Analysis Of Bluetongue Virus Serotype 2 Strains Isolated In The Americas Including A Novel Strain From The Western United States, Natasha N. Gaudreault, Christie E. Mayo, Dane C. Jasperson, Beate M. Crossley, Richard E. Breitmeyer, Donna J. Johnson, Eileen N. Ostlund, N James Maclachlan, William C. Wilson

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Bluetongue is a potentially fatal arboviral disease of domestic and wild ruminants that is characterized by widespread edema and tissue necrosis. Bluetongue virus (BTV) serotypes 10, 11, 13, and 17 occur throughout much of the United States, whereas serotype 2 (BTV-2) was previously only detected in the southeastern United States. Since 1998, 10 other BTV serotypes have also been isolated from ruminants in the southeastern United States. In 2010, BTV-2 was identified in California for the first time, and preliminary sequence analysis indicated that the virus isolate was closely related to BTV strains circulating in the southeastern United States. In …

Identification Of A Fourth Haplotype Of Bactericera Cockerelli (Hemiptera: Triozidae) In The United States, Kylie D. Swisher, Donald C. Henne, James M. Crosslin

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

The potato psyllid, Bactericera cockerelli (Sulc) (Hemiptera: Triozidae), is a pest of potato and other solanaceous crops in North and Central America and New Zealand. Previous genotyping studies have demonstrated the presence of three different haplotypes of B. cockerelli in the United States corresponding to three geographical regions: Central,Western, and Northwestern. These studies utilized psyllids collected in the western and central United States between 1998 and 2011. In an effort to further genotype potato psyllids collected in the 2012 growing season, a fourth B. cockerelli haplotype was discovered corresponding to the Southwestern United States geographical region. High-resolution melting analyses identified …