Digital Commons Network^™

Cancer Stem Cells: Emerging Actors In Both Basic And Clinical Cancer Research, Di̇dem Karakaş, Buse Cevatemre, Engi̇n Ulukaya

Turkish Journal of Biology

Cancer stem cells (CSCs) are a small subset of cancer cells within a tumor that are responsible for tumorigenesis and contribute to drug resistance. The CSC displays an anchorage-independent survival, active DNA-repair capacity, and relative quiescence and is capable of self-renewing and maintaining tumor growth and heterogeneity. At the molecular level, there are several signaling pathways (e.g., Wnt/Beta-catenin, Notch, and Hedgehog) to control CSC properties and alteration of these pathways has been recognized as an essential step for CSC transformation. Emerging evidence suggests that CSCs are clinically relevant. These cells are resistant to conventional chemotherapy and radiation treatment. Therefore, CSCs …

Loss Of Heterozygosity In Ing3 And Ing5 Genes In Breast Cancer, Esra Gündüz, Gökhan Nas, Muradi̇ye Acar, Eyyüp Üçtepe, Mi̇kdat Bozer, Murat Öznur, Reyhan Bayrak, Mehmet Gündüz

Turkish Journal of Biology

The tumor suppressor genes (TSGs) ING3 and ING5, members of the inhibitor of growth gene family, are effective in inhibition of cell growth and induction of apoptosis. However, in many cancer types, one of the alleles of a TSG is lost through carcinogenesis, while the remaining allele is usually inactivated through a process called loss of heterozygosity (LOH). Previous studies in head and neck cancer revealed that allelic loss and reduced expression is a common pattern of ING gene family members. Fifty paraffin-embedded breast cancer tissues were analyzed by polymerase chain reaction and denatured-polyacrylamide gel electrophoresis for LOH status. The …

Cancer Chemopreventive Effect Of Dietary Zataria Multiflora Essential Oils, Abolfazl Dadkhah, Faezaeh Fatemi, Mohammad Reza Mohammadi Malayeri, Azadeh Rasooli

Turkish Journal of Biology

Zataria multiflora Boiss., with the common name Avishan-e-Shirazi, is native to Iran. This herb has been found to possess varied pharmacological properties. In the present study, for the first time, colon chemopreventive effects of Z. multiflora essential oils (0.01% and 0.1% in the diet) in rats treated with 1,2-dimethylhydrazine (DMH) were demonstrated. For this purpose, the oxidative stress/antioxidant parameters (lipid peroxidation, glutathione, superoxide dismutase, catalase, and ferric reducing ability of plasma) concomitant with xenobiotic metabolizing enzymes (CYP450 and GST) were considered. Moreover, the colonic Beta-catenin protein was examined in colon tissues followed by histopathological analysis. The results showed that the …

Health-Related Quality Of Life In Individuals With Chronic Ankle Instability, Megan N. Houston, Bonnie L. Van Lunen, Matthew C. Hoch

Rehabilitation Sciences Faculty Publications

Context: Individuals with chronic ankle instability (CAI) have reported decreased global and regional function. Despite the identification of functional deficits in those with CAI, more research is required to determine the extent to which CAI influences the multidimensional profile of health-related quality of life.

Objective: To determine whether global, regional, and psychological health-related outcomes differ between individuals with and without CAI.

Design: Case-control study.

Setting: Laboratory.

Patients or Other Participants: Twenty-five participants with CAI (age = 21.9 ± 2.5 years, height = 170.8 ± 8.6 cm, mass = 69.8.0 ± 11.7 kg) were sex- and limb-matched to 25 healthy participants …

Concurrent Validity Of Accelerations Measured Using A Tri-Axial Inertial Measurement Unit While Walking On Firm, Compliant, And Uneven Surfaces, Michael H. Cole, Wolbert Van Den Hoorn, Justin K. Kavanagh, Steven Morrison, Paul W. Hodges, James E. Smeathers, Graham K. Kerr

Rehabilitation Sciences Faculty Publications

Although accelerometers are extensively used for assessing gait, limited research has evaluated the concurrent validity of these devices on less predictable walking surfaces or the comparability of different methods used for gravitational acceleration compensation. This study evaluated the concurrent validity of trunk accelerations derived from a tri-axial inertial measurement unit while walking on firm, compliant and uneven surfaces and contrasted two methods used to remove gravitational accelerations; i) subtraction of the best linear fit from the data (detrending); and ii) use of orientation information (quaternions) from the inertial measurement unit. Twelve older and twelve younger adults walked at their preferred …

Future Directions Of Evidence-Based Practice In Athletic Training: Perceived Strategies To Enhance The Use Of Evidence-Based Practice, Cailee E. Welch, Dorice A. Hankemeier, Aimee L. Wyant, Danica G. Hays, William A. Pitney, Bonnie L. Van Lunen

Rehabilitation Sciences Faculty Publications

Context: The shift to a culture of evidence-based practice (EBP) in athletic training is a necessary step in both the optimization of patient care and the advancement of athletic trainers (ATs) as health care professionals. Whereas individuals have gained knowledge in this area, most ATs still are not practicing in an evidence-based manner. Exploring perceived strategies to enhance the use of EBP will help to determine the best approaches to assist ATs in applying EBP concepts to practice to improve patient care.

Objective: To explore beneficial strategies and techniques ATs perceived would promote successful implementation of EBP within athletic training …

Injury Prevention With Physical Therapy, Karen Kott, Margaret F. Lemaster

Rehabilitation Sciences Faculty Publications

(First paragraph) Ergonomics is the study of human performance (positioning and movement) and workplace design, such as equipment, ambience, and placement. The purpose of ergonomics is to maximize productivity by increasing safety, improving work quality, reducing operator fatigue and discomfort, and decreasing the risk of work -related musculoskeletal disorders (MSDs).^1-3

The Role Of Laryngeal Function In Breathing For Singing, Ellen V. Graham

Theses and Dissertations--Music

Poor breath management is problematic for singing. Voice students and singing teachers typically attribute breath management issues to abdominal-diaphragmatic breathing technique. The present study seeks to determine whether glottal insufficiency may also contribute to singer’s breath management problems. Studies have revealed a relationship between incomplete vocal fold closure and inefficiency in the speaking voice. However, the effect of incomplete vocal fold closure on vocal efficiency in singers has yet to be determined. Since the larynx cannot be observed without the assistance of clinical instrumentation, not readily available in the voice studio, issues at the glottal level may be underappreciated as …

A Study Of J.S. Bach’S Sacred And Secular Vocal Works Influenced By Popular Stylized Dance Of The French Baroque Court: A Performer’S Guide, Dione J. Napier

Theses and Dissertations--Music

Among the existing body of literature on J.S. Bach’s massive compositional output, a scarce percentage of this research is dedicated specifically to the study of French Baroque court dances and their influence on Bach’s solo vocal repertoire. This study presents secular and sacred solo vocal works by J.S. Bach that were influenced by popular French court dances of the eighteenth century. The study explores musical and dance traits extracted from some of the most popular French Baroque court dances and incorporated into solo vocal repertoire. The intent of this paper is to provide a resource from a performer’s perspective that …

The Effect Of Family Centered Music Therapy Sessions On Relaxation States Of Informal Caregivers Of Hospice And Palliative Care Patients, Adrienne Claire Steiner

Theses and Dissertations--Music

Advances in healthcare and shifts toward patient and family centered care have allowed healthcare professionals to focus on the entirety of a patient and what affects his/her health. In noting such changes, and in consideration of what affects quality of life, findings in the literature address the physiological and physiological differences between those who are caregivers versus those who are not caregivers. This study investigated the relaxation state of those who were considered informal caregivers of hospice and palliative patients in an acute hospitalized setting.

A family centered music therapy session was conducted utilizing a music-­‐ assisted relaxation intervention incorporating …

Zilphia Horton, A Voice For Change, Alicia R. Massie-Legg

Theses and Dissertations--Music

This dissertation examines the role of Zilphia Horton (1910-1956) in helping to establish the use of music as a powerful tool to unify and train groups involved in social reform at seminars led by Highlander Folk School. In engaging in what has been termed the “mobilization of music,” Mrs. Horton was active in labor disputes, training seminars in the United States and Canada, and the formation of women’s union auxiliaries from 1935 until 1956. The study uses correspondence written by Horton to her husband, Myles Horton; business letters to labor union officials and contributors to songsters; and writings revealing her …

Table Of Contents

University of Maryland Law Journal of Race, Religion, Gender and Class

No abstract provided.

Adobe Medicus 2014 1 January-February, Health Sciences Library And Informatics Center

adobe medicus

No abstract provided.

Automated Vehicles Are Probably Legal In The United States, Bryant Walker Smith

Texas A&M Law Review

This article provides the most comprehensive discussion to date of whether so-called automated, autonomous, self-driving, or driverless vehicles can be lawfully sold and used on public roads in the United States. The short answer is that the computer direction of a motor vehicle’s steering, braking, and accelerating without real-time human input is probably legal. The long answer, which follows, provides a foundation for tailoring regulations and understanding liability issues related to these vehicles.

The article’s largely descriptive analysis, which begins with the principle that everything is permitted unless prohibited, covers three key legal regimes: the 1949 Geneva Convention on Road …

Procedural Architecture Matters: Innovation Policy At The Federal Communications Commission, J. Brad Bernthal

Texas A&M Law Review

This Article examines the puzzle of whether today’s Federal Communications Commission (“FCC” or the “Agency”) is institutionally suited to craft telecommunications innovation policy and, if not, what changes are needed to better equip the Agency to respond to twenty-first century realities. Evaluation of FCC innovation policy performance is stubbornly difficult. Some criticize the FCC as a brake on innovation yet, under the FCC’s oversight, the United States’ communications industry has become an innovative engine propelling the overall economy more than ever before. It is difficult to untangle whether the FCC deserves credit for helping usher in today’s communications age, whether …

The Precarious Position Of Same-Sex Divorce In Texas, Shawna M. Young

Texas A&M Law Review

Currently, same-sex couples that are legally married in a jurisdiction that recognizes same-sex marriage may not be able to divorce if they move to Texas. Of the few cases tried in Texas, most courts refused to grant the samesex divorce because the courts refused to recognize the underlying marriage. Because these couples cannot simply return to the granting state due to most states’ divorce residency requirements, they cannot divorce and face untold issues due to this inability. While Texas does offer the opportunity for the couple to declare the marriage void, declaring the marriage void is not an adequate legal …

Caught Between A Rock, Negligence, Racism, And A Hard Place: Exploring The Balance Between The Eeoc’S Arrest And Conviction Investigation Guidelines And Society’S Best Interest, Eniola O. Akinrinade

Texas A&M Law Review

In many instances, employers have an obligation to conduct criminal background checks on their applicants to ensure that the public that comes into contact with these employees shall not be harmed. In other instances, these criminal background checks are unnecessary as they prove to be of little relevance, yet they have the effect of causing a disparate impact within certain Title VII-protected classes, including Black Americans and Hispanics.

To resolve this disparate impact, the Equal Employment Opportunity Commission (“EEOC”) has set forth non-biding guidance, proposing an assessment of “Green Factors” that employers should consider before denying an ex-convict employment. In …

A Need To Climb High To Integration Ladder, Nazish Fatima, Syed Muhammad Faizan Ul Haque

Department for Educational Development

No abstract provided.

Measuring The Good Life: An Evaluation Of Alternatives To Gdp, Meg Oka

Whittier Scholars Program

Gross domestic product (GDP) is one of the most widely watched and reported statistic of economic assessment. It measures the market value of all final goods and services produced in a country for a year. The White House, Congress, the Federal Reserve, Wall Street and business all use it for various purposes for preparing the Federal budget to planning production and investment. It is clear that GDP is widely utilized by countries, international agencies and the popular media and is an influential factor in domestic and global policy, legislature and debate. The GDP is only a measure for economic activity …

The Concept Of Creativity In Art And In Science: Are Autistic People Creative?, Miguel López Astorga

Khazar Journal of Humanities and Social Sciences

Usually, autism is said to be characterized by certain difficulties related to lack of creativity. In this paper, based on the arguments offered by McKenzie and paying attention to the neurodiversity perspective, it is held that the concept of creativity has not been understood correctly, and that, if the artistic field is considered, it can be stated that people with autism can be creative, because creativity can be linked to repetition and details. In this way, it is argued that the repetitive and thorough actions that autistic people often make can have beneficial impacts on art, on the development of …

Jump In Before It's Too Late: Protecting And Increasing Streamflows In New Mexico, Sharon Wirth

Law of the Rio Chama

Freshwater ecosystems need adequate streamflow to supply clean water for humans and maintain healthy habitat for wildlife. Over-appropriation, overuse, climate change, and drought plague New Mexico's rivers, taxing many rivers beyong sustainability. Despite the myriad of problems caused by little or no water in our rivers, policies and procedures to protect and increase streamflows in New Mexico are limited. While most Western states have made demonstrable progress in alleviating various legal and technical barriers to protecting and increasing streamflows, New Mexico has made only limited, recent progress towards solutions for our drying rivers. This article takes a critical look at …

Water Governance Challenges In New Mexico's Middle Rio Grande Valley: A Resilience Assessment, Melinda Harm Benson, Dagmar Llewellyn, Ryan Morrison, Mark Stone

Law of the Rio Chama

No abstract provided.

Parish Memorial Library 45th Anniversary, Patricia Campbell

Celebrations

Parish Memorial Library celebrated 45 years of providing services to UNM and the community during October and November 2014, with a lecture series and exhibit.

An exhibit of photos and other materials illustrating the history of the library was on display in Parish Memorial Library during Fall Semester 2014.

Differential Influence Of The Great Recession On Political Participation Among Race And Ethnic Groups, Kimberly R. Huyser, Jillian Medeiros Pérez, Vickie Ybarra, Julia Marin Hellwege, Lisa Sanchez

Sociology Faculty and Staff Publications

Our study seeks to understand the role of perceived economic stress of the Great Recession on political participation among blacks, whites and Latinos. Methods. We use the 2012 Collaborative Multi-Racial Political Study and negative binomial regression to examine the impact of financial hardship on black, Hispanic, and white political participation. Results. We find that political participation among whites is unaffected by the Great Recession and is largely motivated by political interest. Blacks are mobilized by financial hardship even after controlling for political enthusiasm and linked fate. Hispanics have the lowest level of political participation. Conclusion. Overall, we conclude that the …

Letter From The Co-Editors, Unm Department Of Orthopaedic Surgery

UNM Orthopaedic Research Journal

No abstract provided.

Alumni Map, Unm Department Of Orthopaedic Surgery

UNM Orthopaedic Research Journal

No abstract provided.

Tourniquets—A Review With Recommendations, Seth Mccord

UNM Orthopaedic Research Journal

No abstract provided.

Treatment Of Hallux Valgus With A Chevron Osteotomy Combined With A Lateral Release, Selina Silva, Richard A. Miller

UNM Orthopaedic Research Journal

Purpose: Current literature recommends proximal first metatarsal osteotomy for large hallux valgus deformities. Combined distal osteotomy with lateral release can be done and may provide a similar degree of correction. The concern with this technique is disruption of the blood supply to the first metatarsal head. We hypothesized that a chevron osteotomy in conjunction with a lateral release is effective in correcting some larger hallux valgus deformities without causing disruption of the blood supply to the first metatarsal head.

Methods: We reviewed the imaging studies of fortysix cases that underwent a distal chevron osteotomy with lateral release for correction of …

The Use Of Human Amniotic Membrane For Cartilage Repair: A Sheep Study, Samuel K. Tabet, David M. Conner

UNM Orthopaedic Research Journal

No abstract provided.

Pediatric Proximal Ulna Plastic Deformation With Anterior Radial Head Dislocation — A Rural Monteggia Fracture Two Weeks Out In A Tertiary Care Center: A Case Report, Luke Buthuis, Selina Silva

UNM Orthopaedic Research Journal

The Monteggia fracture was originally described over two centuries ago. These fractures of the proximal one-third of the ulnar shaft with associated anterior dislocation of the radial head and its variants are well described and still an area of active debate. There is the additional challenge today of tertiary referral centers providing specialized care for this injury in the pediatric population, resulting in missed diagnosis and late referrals. This is a case report of one such patient, an eight-year old female referred to our center two weeks post injury with the diagnosis of an un-reducible radial head dislocation.