Digital Commons Network^™

Extent Of Cysteine Modification Of Snap-25 In Vitro, Alex Mcgregor Dabell

Theses and Dissertations

Exocytosis, the fusion of a vesicle to a cellular membrane, involves a protein named SNAP-25. This protein, containing two alpha helices connected with a linker region, is localized to the cell membrane via palmitic acids attached to the cysteine residues of its linker region in a process called palmitoylation. Are cysteine residues of the SNAP-25 linker region palmitoylated in an ordered manner and to a particular extent? The answer to this question may give insight into the regulated nature of exocytosis. While it is generally accepted that SNAP-25 must be palmitoylated in order to perform its exocytotic functions, the details …

Language Pathways Defined In A Patient With Left Temporal Lobe Damagesecondary To Traumatic Brain Injury: A Qeeg & Mri Study, Janelle Lee Bailey

Theses and Dissertations

Though the current understanding of language processing is incomplete, it has been established that the left hemisphere is dominant for language in the majority of the population. Damage to language centers of the brain and to white matter tracts connecting these language centers results in a language deficit known as aphasia. Neuroplasticity in the brain can often compensate for these language deficits by strengthening neuronal connections between the right and left hemisphere, or by enhancing the neuronal connectivity of undamaged areas in the left hemisphere. Thus the brain can compensate for damaged language centers by using alternative cortical areas. These …

Openline Newsletter, December 2014, Civil Service Council

OpenLine Newsletter

A monthly newsletter for Civil Service employees, Volume 39, Number 5, December 2014.

Laminar And Turbulent Regime Changes In Drinking Water Contact Tanks, Taylor C. Barnett, Subhas K. Venayagamoorthy

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

Transitions in flow regimes that can occur in drinking water contact tanks may significantly affect the disinfection efficiency of the system. To demonstrate these effects, the authors investigated the internal velocity fields and flow regime of a drinking water contact tank located in Jamestown, Colo. The baffling factor (BF) of the system fluctuated annually between 0.5 and 0.6 because of a shift in flow regime caused by changes in the flow rate of the system. The authors studied the effects of the regime change from laminar to turbulent flow (or vice versa) using computational fluid dynamics (CFD) models and physical …

Phytoscreening: A Comparison Of In Planta Portable Gc-Ms And In Vitro Analyses, Matt A. Limmer, Gregory D. Martin, Christopher J. Watson, Camilo Martinez, Joel Gerard Burken

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

Phytoscreening Has Been Proven to Rapidly Delineate Subsurface Contaminant Plumes for Semiquantitative Site Assessment, with Minimal Impact to Property or Ecology through the Collection and Analysis of Tree Cores. Here, Three Phytoscreening Methods Were Applied Concurrently to Identify Multiple Chlorinated Volatile Organic Compounds (CVOCs) in a Phytoremediation Treatment System at a Contaminated Industrial Facility. Tree Coring, in Planta Gas Chromatography-Mass Spectrometry (GC-MS), and in Planta Passive Sampling Showed General Agreement, with the in Planta GC-MS Providing the Quickest But Least Quantitative Results. the Portable GC-MS Sampling and Analysis Method Identified Six CVOCs in the Xylem of Hybrid Poplars (Populus Sp.) …

Stability Design Criteria For Distribution Systems With Solid-State Transformers, Darshit G. Shah, M. L. Crow

Electrical and Computer Engineering Faculty Research & Creative Works

Due to recent advancements in semiconductor technology, power-electronic converters for high-voltage, high-power, and high-frequency applications will soon be commercially available. The theoretical concept of a distribution solid-state transformer (SST) is not recent, but with the use of advanced electronic switches and control strategies, the SST may soon become a practical reality. In this paper, conventional single-phase distribution transformers are replaced by solid-state transformers in a distribution test system to investigate their interactive dynamics. Under certain circumstances, instabilities due to harmonic resonance are observed. A design criterion for a solid-state transformer during no-load conditions has been proposed in order to avoid …

Structure’S Impact On Homiletic Rhetoric: A Case Study Of Melissa Scott’S Preaching, Erik S. Nelson

Honors Theses

Though the connection between the study of rhetorical processes and the practice of expository preaching is obvious, academic cooperation between the two fields is lacking. This case study presents an example of the harmony achievable between the disciplines through the production of constructive criticism, a process known to communication scholars as rhetorical analysis, for a sample of sermons given by Pastor Melissa Scott in recent years. Scott, whose preaching style is uniquely centered on translation-based exposition, represents the modern pastor whose skill and technique might be improved upon with the implementation of recent and emerging communication theory. Specifically, this study …

Nurse Knowledge Of Clostridium Difficile, Ashley E. Frosch

Honors Theses

The purpose of this study is to determine the amount of knowledge nurses have about Clostridium difficile. Seventy-five nurses participated in this study. A 25-question true/false survey was distributed via email to graduates of The University of Southern Mississippi. The survey consisted of a brief demographic section and 25 questions addressing Clostridium difficile knowledge. A total of 582 surveys were sent out with a total of 75 completed. Out of 25 questions in the survey, the majority of respondents (>50%) only answered 7 questions incorrectly. Overall, the nurses in this study possessed accurate knowledge about C. difficile; although, there …

The Complexity Of Common Core: Teaching Harry Potter And The Half-Blood Prince As A 7th Grade Complex Text, Allyson R. Jones

Honors Theses

With the implementation of the Common Core State Standards occurring across the country, schools and students are seeing changes in the organization of education. These standards, grounded in English Language Arts and Mathematics, are designed to push students’ critical thinking skills, writing ability, and methods of communication to prepare them for their life beyond secondary education. For English Language Arts, there is an emphasis on teaching complex texts. In this study, I examined the qualities of complex texts to determine if Harry Potter and the Half-Blood Prince could be considered a teaching tool for seventh grade students. To do this, …

Psychometric Properties Of The Arabic Version Of The Perceived Physical Ability  Scale For Children In Oman, Sabry M. Abd-El-Fattah

Journal of Educational and Psychological Studies

This study aimed at examining the psychometric properties of the Perceived Physical Ability Scale for Children (PPASC) within an Omani context. A sample of 250 fourth graders (130 males and 120 females) from six public primary schools in four governorates in Oman responded to Arabic translated version of the PPASC. Data on students' in-class physical activity, social desirability, and teachers' nominations of students' physical ability were also collected. Confirmatory factor analysis revealed that the unidimensional model of the PPASC had adequate fit to the data. Multigroup CFA revealed gender invariance for PPASC unidimensional model when it was compared across male …

Theoretical And Experimental (E, 2e) Study Of Electron-Impact Ionization Of Laser-Aligned Mg Atoms, Sadek Amami, Andrew J. Murray, Al Stauffer, Kate Nixon, Gregory Armstrong, James Colgan, Don H. Madison

Physics Faculty Research & Creative Works

We have performed calculations of the fully differential cross sections for electron-impact ionization of magnesium atoms. Three theoretical approximations, the time-dependent close coupling, the three-body distorted wave, and the distorted wave Born approximation, are compared with experiment in this article. Results will be shown for ionization of the 3s ground state of Mg for both asymmetric and symmetric coplanar geometries. Results will also be shown for ionization of the 3p state which has been excited by a linearly polarized laser which produces a charge cloud aligned perpendicular to the laser beam direction and parallel to the linear polarization. Theoretical and …

X-Ray Emission Produced In Charge-Exchange Collisions Between Highly Charged Ions And Argon: Role Of The Multiple Electron Capture, Sebastian Otranto, N. D. Cariatore, Ronald E. Olson

Physics Faculty Research & Creative Works

In this work we use the classical trajectory Monte Carlo method within an eight-electron scheme to theoretically study photonic spectra that follow charge-exchange processes between highly charged ions of charge states 10+, 17+, 18+, and 36+ with neutral argon. The energy range considered is 18 eV/amu to 4 keV/amu, covering typical electron beam ion traps and solar wind energies. The role played by multiple electron capture processes for the different collision systems under consideration is explicitly analyzed and its contribution separated as arising from radiative decay and autoionizing multiple capture. For the present collision systems we find that multiple electron …

Understanding Higher-Order Nonlocal Halo Bias At Large Scales By Combining The Power Spectrum With The Bispectrum, Shun Saito, Tobias Baldauf, For Full List Of Authors, See Publisher's Website.

Physics Faculty Research & Creative Works

Understanding the relation between underlying matter distribution and biased tracers such as galaxies or dark matter halos is essential to extract cosmological information from ongoing or future galaxy redshift surveys. At sufficiently large scales such as the baryon acoustic oscillation (BAO) scale, a standard approach for the bias problem on the basis of the perturbation theory (PT) is to assume the "local bias" model in which the density field of biased tracers is deterministically expanded in terms of matter density field at the same position. The higher-order bias parameters are then determined by combining the power spectrum with higher-order statistics …

First All-Sky Search For Continuous Gravitational Waves From Unknown Sources In Binary Systems, J. Aasi, Marco Cavaglia, For Full List Of Authors, See Publisher's Website.

Physics Faculty Research & Creative Works

Gravitational waves from a variety of sources are predicted to superpose to create a stochastic background. This background is expected to contain unique information from throughout the history of the Universe that is unavailable through standard electromagnetic observations, making its study of fundamental importance to understanding the evolution of the Universe. We carry out a search for the stochastic background with the latest data from the LIGO and Virgo detectors. Consistent with predictions from most stochastic gravitational-wave background models, the data display no evidence of a stochastic gravitational-wave signal. Assuming a gravitational-wave spectrum of Ω_GW(f) = Ω_{α …}

Improved Upper Limits On The Stochastic Gravitational-Wave Background From 2009-2010 Ligo And Virgo Data, J. Aasi, Marco Cavaglia, For Full List Of Authors, See Publisher's Website.

Physics Faculty Research & Creative Works

Gravitational waves from a variety of sources are predicted to superpose to create a stochastic background. This background is expected to contain unique information from throughout the history of the Universe that is unavailable through standard electromagnetic observations, making its study of fundamental importance to understanding the evolution of the Universe. We carry out a search for the stochastic background with the latest data from the LIGO and Virgo detectors. Consistent with predictions from most stochastic gravitational-wave background models, the data display no evidence of a stochastic gravitational-wave signal. Assuming a gravitational-wave spectrum of ΩGW(f)=Ωα±(f/fref)α±, we place 95% confidence level …

Multiple Osteochondromas In A 16th–19th Century Individual From Setúbal (Portugal), Nathalie Antunes-Ferreira, Eugénia Cunha, Carina Marques

Anthropology Faculty Publications

An archaeological survey at the church of Nossa Senhora da Anunciada (Setúbal, Portugal) uncovered the remains of 92 individuals. Historical and archaeological data suggest that the inhumations occurred between 1531 and 1839. The present work reports the pathological features of a mature male individual exhibiting multiple osseous bony projections and bone deformity, mainly affecting the metaphyseal and adjacent diaphyseal regions of the long bones. The macroscopic and the radiological analyses of the lesions suggest multiple osteochondromas as the most probable diagnosis. This is the first archaeological case of this disease known on the Portuguese territory and in southern Europe.

Nutrition Students’ Perception Of Osce & Its Effect On Perceived Readiness To Clinical Placement, Elaf Farahat

Loma Linda University Electronic Theses, Dissertations & Projects

Objective: Explore nutrition and dietetic students’ perception of the educational value of Objective Structured Clinical Examinations (OSCE) and to examine the change in their perceived readiness to practice after completing three OSCEs.

Participants: Students from the Schools of Public Health (SPH) and Allied Health Professions (SAHP) enrolled in Medical Nutrition Therapy course, mean age 26.6±5.4 years, 95% females (n=37).

Methods: Mixed-method sequential exploratory design. Three focus group discussions (11 participants) were conducted as part of the qualitative phase to elicit themes related to perception of OSCE as an education tool. In the quantitative phase, a pre-post test design …

The Effect Of Grapes In Mice With Alzheimer's Disease And Brain Injury, Nikita Mistry

Loma Linda University Electronic Theses, Dissertations & Projects

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder resulting in cognitive and memory deficits and deposits of amyloid beta (Aβ) in the cortex and hippocampus are thought to be significant contributors to the disease process. Increasing evidence suggests that foods rich in polyphenols, such as pomegranates and grapes, may have neuroprotective effects in both rodents and humans. Our previous research has shown that a pomegranate-enriched diet decreased Aβ plaque load and improved behavior in Tg2576 mice. In this study, we determined whether a grape-enriched diet altered Aβ neuropathology and TBI in PSAPP mice. Mice received either craniotomy or a moderate …

The Role Of Claudins In Bone Metabolism, Fatima Zakariya Alshbool

Loma Linda University Electronic Theses, Dissertations & Projects

Osteoporosis, a major public health problem in the U.S., is characterized by low bone mass and structural deterioration of bone tissue. Since the imbalance between bone formation and bone resorption during bone remodeling has been documented to be a major factor in the pathogenesis of osteoporosis, it is crucial to identify novel genes and/or novel functions of known genes that regulate the formation and activity of bone forming osteoblasts and bone resorbing osteoclasts. To this end, recent evidence suggests a significant role for caudins (Cldns), which comprise a major group of tight junction proteins, in bone biology and development. This …

Modulation Of T Lymphocytes By Tumor-Released Survivin, Jessica Marie Jutzy

Loma Linda University Electronic Theses, Dissertations & Projects

The tumor microenvironment is an area of intense interaction between normal and malignant cells. Factors and cell types within this environment can play a crucial role in the progression or regression of the tumor. Of primary interest are tumor-infiltrating T lymphocytes, which have been shown to have a key role in modifying the dynamics of the tumor microenvironment to promote or prevent tumor growth. While there is much in vitro and in vivo evidence for a modification of the tumor infiltrating T cell population toward a pro-tumor environment, what induces these changes within the tumor microenvironment has remained elusive. Our …

Stereotypes About Healthcare Professionals, Emotions, And Mammography Compliance, Kayla M. Kinworthy

Loma Linda University Electronic Theses, Dissertations & Projects

Rates of mammography screening are particularly low for minority women, with only 42% of Latin American (Latino) women in the U.S. reporting having a mammogram in the last year as compared to 53% of non-Latino White (Anglo) women [1]. Minority patients are more likely to report negative healthcare encounters with their health professionals [2; 3], which may result in less favorable cultural stereotypes about healthcare professionals and more negative emotional reactions. Guided by Betancourt’s Integrative Model of Culture, Psychological Processes, and Health Behavior [4] and the Stereotype Content Model [5], the aim of the present research was to examine the …

The Use Of Surface Cytokines As Biomarkers In B Cell Mediated Autoimmune Diseases, Abby Jones Weldon

Loma Linda University Electronic Theses, Dissertations & Projects

RA and SLE are B cell-mediated autoimmune diseases dominated by autoantibodies that affect over 1.5 million Americans. Together RA and SLE contribute to over 29 billion in healthcare costs, therefore due to the high financial burden and physical toll of these diseases on the population, there is a critical need to effectively and efficiently diagnose and treat RA and SLE patients. The aim of our studies was to identify biomarkers and drug targets to improve the identification and treatment of RA and SLE patients. As discussed above, APRIL, BAFF and TSLP have been implicated in the pathogenesis of RA and …

Cardioguard: A Brassiere-Based Reliable Ecg Monitoring Sensor System For Supporting Daily Smartphone Healthcare Applications, Sungjun Kwon, Jeehoon Kim, Seungwoo Kang, Youngki Lee, Hyunjae Baek, Kwangsuk Park

Research Collection School Of Computing and Information Systems

We propose CardioGuard, a brassiere-based reliable electrocardiogram (ECG) monitoring sensor system, for supporting daily smartphone healthcare applications. It is designed to satisfy two key requirements for user-unobtrusive daily ECG monitoring: reliability of ECG sensing and usability of the sensor. The system is validated through extensive evaluations. The evaluation results showed that the CardioGuard sensor reliably measure the ECG during 12 representative daily activities including diverse movement levels; 89.53% of QRS peaks were detected on average. The questionnaire-based user study with 15 participants showed that the CardioGuard sensor was comfortable and unobtrusive. Additionally, the signal-to-noise ratio test and the washing durability …

Newsletter, December 2014, Aaup Chapter, Illinois Wesleyan University

Chapter Activities

No abstract provided.

Law’S Evolution And Law As Custom, William A. Edmundson

San Diego Law Review

normative, and law works by channeling custom-in-gross into progressively finer and more precise grooves. If there is normative moral value resident in the custom of elevating and following leaders, then that normativity ought to flow downstream into the finer channels officials carve and into the fresh territory they wish us to occupy. In places, that flow is too diluted, and normativity trails off. In places, officials direct the stream over a cliff, and it is no longer normative at all. In places, the stream is overtaken by stronger normative streams and can only make a difference yet farther downslope, where …

Freedom, Benefit And Understanding: Reflections On Laurence Claus’S Critique Of Authority, John Finnis

San Diego Law Review

With wide-ranging and illuminating determination, Law’s Evolution and Human Understanding offers a refutation of the illusion of authority. No one, it rightly contends, has the right to be obeyed. Still less, as it correctly says, do any persons have the right that their say so be obeyed because they said so. Given the book’s stipulative definition of “authority,” these truths entail that authority is an illusion, and provide some important premises for a plausible further conclusion or pair of conclusions: it is harmful, both in practice and in theory, to say that some person or body has authority (“the rule …

Why Distinguish Religion, Legally Speaking?, Winnifred Fallers Sullivan

San Diego Law Review

Law professors commonly answer this critique by scholars of religion, as Andrew Koppelman does, with the comment that, after all, any ambiguity in definition only arises in a few cases. Most of the time the reference is obvious, he says. Moreover, he insists, it has worked fine for all those for whom it should work. But that is the problem—its very obviousness. The problems of exclusion are largely invisible. The reference is so obvious to many and so obviously inclusive of those who are deserving that there is no way to have a conversation about it without the conversation devolving …

Orientations Of Low-Energy Domain Walls In Perovskites With Oxygen Octahedral Tilts, Fei Xue, Yijia Gu, Linyun Liang, Yi Wang, Long-Qing Chen

Materials Science and Engineering Faculty Research & Creative Works

Many applications of ferroic materials, such as data storage and spintronics, are achieved through the control and manipulation of their domain wall (DW) orientations and configurations. Here we propose a rotational compatibility condition to identify low-energy DWs in perovskites with oxygen octahedral tilt instability. It is derived from the strong DW energy anisotropy arising from the rigidity and corner-sharing feature of the octahedral network. We analyze quantitatively the DWs in SrTiO₃ and explain successfully the unusual ferroelectric DW width and energy in BiFeO₃.

Computer-Assisted Language Learning (Call) Impact On Students' Reading Achievement And Their Attitude Towards Its Use, Ayeda Abdulla Saeed Al Shebli

Theses

This study sought to investigate the effects of computer-assisted language learning (CALL) on students' reading achievement, and students’ attitudes toward the use of CALL. Two groups of grade 7 students participated in this study. At the beginning of the study, both groups were given a pretest to evaluate these students’ reading skills. In the control group, students were taught through ordinary instruction. On the other hand, in the experimental group; students used CALL to practice their reading skills. At the end of the treatment, both groups were given a posttest in order to determine whether there was any difference in …

Studies On The Initial Stage Of Lipid Oxidation In Bulk Oils, Elizabeth Budilarto

Dissertations

During the oxidation of bulk oils, oxidation products (i.e. peroxide values, conjugated dienes and thiobarbituric acid reactive substances) are formed gradually and increased sharply at the end of the induction period. Tocopherols were consumed, some water was formed, and micelles increased in size during the induction period of vegetable oils oxidized in bulk. The evidence that the evolution of micellar size was in parallel with the end of induction period corroborates the recognition that micelles are the active site of oxidation. The interactions of α-tocopherol and three synergists: ascorbyl palmitate, phosphatidylcholine and L-lysine were studied in cod liver oil, to …