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2014

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Integrating K-W-L Prompts Into Science Journal Writing: Can Simple Question Scaffolding Increase Student Content Knowledge?, Brandon Joel Wagner Sep 2014

Integrating K-W-L Prompts Into Science Journal Writing: Can Simple Question Scaffolding Increase Student Content Knowledge?, Brandon Joel Wagner

Dissertations and Theses

Writing-to-learn strategies have been administered in the past to enrich student learning. The purpose of this study was to see if K-W-L prompts in science journal writing could benefit student content knowledge within biology. Two high school biology classes were provided with learning journals. The journals given to the students during the treatment unit were provided with K-W-L question prompts to guide student learning while during the comparison unit students were given an open ended writing assignment. Pre and posttests were administered to determine student-learning gains. Student motivations and opinions of the treatment were collected through student interviews. The combined …

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The Daily Gamecock, Monday, September 22, 2014, University Of South Carolina, Office Of Student Media Sep 2014

The Daily Gamecock, Monday, September 22, 2014, University Of South Carolina, Office Of Student Media

September

No abstract provided.

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About The Contributors, E-Research Editors Sep 2014

About The Contributors, E-Research Editors

e-Research: A Journal of Undergraduate Work

No abstract provided.

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Mapping Regions Of Rnf168 Required For Its Degradation By Icp0, Andrea Cyr, Matthew Weitzman Sep 2014

Mapping Regions Of Rnf168 Required For Its Degradation By Icp0, Andrea Cyr, Matthew Weitzman

e-Research: A Journal of Undergraduate Work

Viruses establish infection by overtaking host cell processes and developing mechanisms that promote viral replication. Herpes simplex virus undergoes lytic and latent cycles of infection throughout the lifespan of its host. The viral genome is transcriptionally silent during latency, but viral proteins are produced upon reactivation. Herpes simplex virus type 1 encodes the ICP0 protein, an E3 ubiquitin ligase required for reactivation from latency of the infectious virus. The immediate-early protein ICP0 regulates the herpes simplex virus by activating viral gene expression thereby initiating lytic infection. Cellular proteins are degraded by ICP0, promoting the virus to enter the lytic cycle. …

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New Usfsp Grad Publishes Research In National Journal, September 12, 2014, Karlana June Sep 2014

New Usfsp Grad Publishes Research In National Journal, September 12, 2014, Karlana June

USF St. Petersburg Campus News and Press Releases

No abstract provided.

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The Immunological Effectiveness Of Some Common Plants, Anwar I. S. Al-Assaf, Zahraa H. M. Kadri Sep 2014

The Immunological Effectiveness Of Some Common Plants, Anwar I. S. Al-Assaf, Zahraa H. M. Kadri

Baghdad Science Journal

Three plant species were picked randomly and their alcoholic extracts have been screened to know their effects on the phagocytic capability and intracellular killing of yeast by human peripheral macrophages. Macrophage cultures were incubated with different concentration of each plant extract: for 15 min., 30 min .and 45 min. The phagocytes activity in Iresine herbstii extract was significantly (p≤0.05) increased with increasing dose and time of incubation. In Mentha piperita extract, increasing in dose and time of incubation leads to elevate phagocytic capbility, especially in the dose of 20% and 25% of plant extract, perhaps because the antimicrobial and antiviral …

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Composition Of Fish Assemblage In The East Hammar Marsh, Southern Iraq, Abdul Razzaq M. Mohamed, Sadeq. A. Hussein, Falah. M. Mutlak Sep 2014

Composition Of Fish Assemblage In The East Hammar Marsh, Southern Iraq, Abdul Razzaq M. Mohamed, Sadeq. A. Hussein, Falah. M. Mutlak

Baghdad Science Journal

The fish assemblage in the East Hammar marsh was studied during December 2009 to May 2010. The fish fauna of the marsh consisted of 17 native, 23 marine (49%) and seven alien species. The dominant species were Liza abu (14.6%), Carassius auratus (13.4%) and Thryssa mystax (11.2%). The resident species formed 44.7%, occasional species 36.1% and seasonal species 19.2% of the total number of fish species. Fish species diversity index ranged from 1.28 to 2.61, richness from 1.98 to 4.50 and evenness from 0.45 to 0.78. Salinity ranged from 1.45 to 7.74‰. The increase in the proportion of marine species …

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Use Of Cysteine-Reactive Crosslinkers To Probe Conformational Flexibility Of Human Dj-1 Demonstrates That Glu18 Mutations Are Dimers, Janani Prahlad, David N. Hauser, Nicole M. Milkovic, Mark R. Cookson, Mark A. Wilson Sep 2014

Use Of Cysteine-Reactive Crosslinkers To Probe Conformational Flexibility Of Human Dj-1 Demonstrates That Glu18 Mutations Are Dimers, Janani Prahlad, David N. Hauser, Nicole M. Milkovic, Mark R. Cookson, Mark A. Wilson

Department of Biochemistry: Faculty Publications

The oxidation of a key cysteine residue (Cys106) in the parkinsonism-associated protein DJ-1 regulates its ability to protect against oxidative stress and mitochondrial damage. Cys106 interacts with a neighboring protonated Glu18 residue, stabilizing the Cys106-SO2 − (sulfinic acid) form of DJ-1. To study this important post-translational modification, we previously designed several Glu18 mutations (E18N, E18D, E18Q) that alter the oxidative propensity of Cys106. However, recent results suggest these Glu18 mutations cause loss of DJ-1 dimerization, which would severely compromise the protein’s function. The purpose of this study was to conclusively determine the oligomerization state of these mutants using X-ray …

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Nuclear And Mitochondrial Trna-Lookalikes In The Human Genome., Aristeidis G Telonis, Phillipe Loher, Yohei Kirino, Isidore Rigoutsos Sep 2014

Nuclear And Mitochondrial Trna-Lookalikes In The Human Genome., Aristeidis G Telonis, Phillipe Loher, Yohei Kirino, Isidore Rigoutsos

Computational Medicine Center Faculty Papers

We are interested in identifying and characterizing loci of the human genome that harbor sequences resembling known mitochondrial and nuclear tRNAs. To this end, we used the known nuclear and mitochondrial tRNA genes (the "tRNA-Reference" set) to search for "tRNA-lookalikes" and found many such loci at different levels of sequence conservation. We find that the large majority of these tRNA-lookalikes resemble mitochondrial tRNAs and exhibit a skewed over-representation in favor of some mitochondrial anticodons. Our analysis shows that the tRNA-lookalikes have infiltrated specific chromosomes and are preferentially located in close proximity to known nuclear tRNAs (z-score ≤ -2.54, P-value ≤ …

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Functional Roles Of Nucleases In Dna Metabolism And Genome Stability, Justin Lee Sparks Sep 2014

Functional Roles Of Nucleases In Dna Metabolism And Genome Stability, Justin Lee Sparks

All Theses and Dissertations (ETDs)

The work outlined in this dissertation focuses on two distinct areas that are important for genome stability. Both areas focus on DNA repair pathways that require the action of nucleases, specifically Exonuclease 5 and Ribonuclease H2. First, I describe the biochemical and molecular characterization of the novel Exonuclease 5 family of enzymes from S. cerevisiae, S. pombe, and humans. The Exo5 family consists of bi-directional single-strand DNA specific exonucleases that all contain an iron-sulfur cluster as a structural motif and all have various roles in DNA metabolism. In the Saccharomycetales order that includes the budding yeast, S. cerevisiae, Exo5 is …

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Discovery And Characterization Of Novel Polyomaviruses In Humans, Erica Anne Siebrasse Sep 2014

Discovery And Characterization Of Novel Polyomaviruses In Humans, Erica Anne Siebrasse

All Theses and Dissertations (ETDs)

The family Polyomaviridae is comprised of small, double-stranded DNA viruses of approximately 5,000 base pairs. Two polyomaviruses are well-established human pathogens and cause significant morbidity and mortality in immunocompromised patients. These viruses were discovered in the 1970s, but the last seven years have seen an explosion of novel human polyomavirus discoveries. The work described here seeks to address two questions: "Are there additional, novel polyomaviruses infecting humans?" and "Do these polyomaviruses cause disease in their human hosts?" The discovery of an additional novel polyomavirus, MW polyomavirus (MWPyV), is described. MWPyV was discovered in the stool of a healthy child from …

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The Statesman, V. 58, I. 02, Stony Brook University Aug 2014

The Statesman, V. 58, I. 02, Stony Brook University

Stony Brook Statesman-Sucolian

v. 58, i. 02

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Morphology And Function Of The Drinking Apparatus In Hummingbirds, Alejandro Rico-Guevara Aug 2014

Morphology And Function Of The Drinking Apparatus In Hummingbirds, Alejandro Rico-Guevara

Doctoral Dissertations

My research aims to answer the questions: How do hummingbirds feed? And, how do the mechanics of feeding define the limits and adaptive values of feeding behaviors? I meticulously study every step of nectar capture and ingestion. My dissertation chapters are organized following a morpho-functional and feeding sequence approach: 1) Feeding Apparatus Morphology; with emphasis on the understudied morphology of the tongue grooves and bill tongue coupling. 2) Tongue Tip Dynamics; how hummingbird tongues entrap nectar. 3) Tongue Grooves Functioning: how the tongue acts as an elastic micropump while collecting nectar. 4) Bill Tip Mechanics; internal bill structures that aid …

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Engineering Biosensors For Short-Chain Alcohols, Yu Xia Aug 2014

Engineering Biosensors For Short-Chain Alcohols, Yu Xia

McKelvey School of Engineering Graduate Student Theses & Dissertations

Biofuel is a promising substitute for fossil fuel and the research of biofuel production has been extensively conducted during the recent years. Great efforts have been made to create many types of the fuel production hosts. However, effective approaches for high specificity and high throughput screening of the fuel production strains are still lacking. The cellular stress response is one universal defense mechanism when a microbial cell is exposed to an unfavorable substance or environment. It triggers a series of downstream responses when a cell senses certain chemicals. Transcriptional factors are widely used in living organisms to regulate gene expression. …

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Conservation Of Bridle Shiner (Notropis Bifrenatus) In Connecticut: Issues In Detecting An Elusive Species, Kasey C. Pregler Aug 2014

Conservation Of Bridle Shiner (Notropis Bifrenatus) In Connecticut: Issues In Detecting An Elusive Species, Kasey C. Pregler

Master's Theses

Bridle Shiner (Notropis bifrenatus) is apparently declining over most of its range and is currently listed as a species of concern in Connecticut. Using an occupancy modeling framework in program PRESENCE, my study compared seining and electrofishing backpack unit detection probabilities of Bridle Shiner. This research indicated the apparent decline of Bridle Shiner in the state was in part due to changes in sampling gear used for statewide surveys. Seining used 50 years ago was demonstrably more effective at capturing Bridle Shiner than the currently favored and more frequently used electrofishing gear. In light of this recent finding, …

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Epoxide-Mediated Differential Packaging Of Cif And Other Virulence Factors Into Outer Membrane Vesicles, A. E. Ballok, L. M. Filkins, J.. M. Bomberger, B. A. Stanton, George A. O'Toole Aug 2014

Epoxide-Mediated Differential Packaging Of Cif And Other Virulence Factors Into Outer Membrane Vesicles, A. E. Ballok, L. M. Filkins, J.. M. Bomberger, B. A. Stanton, George A. O'Toole

Dartmouth Scholarship

Pseudomonas aeruginosa produces outer membrane vesicles (OMVs) that contain a number of secreted bacterial proteins, including phospholipases, alkaline phosphatase, and the CFTR inhibitory factor (Cif). Previously, Cif, an epoxide hydrolase, was shown to be regulated at the transcriptional level by epoxides, which serve as ligands of the repressor, CifR. Here, we tested whether epoxides have an effect on Cif levels in OMVs. We showed that growth of P. aeruginosa in the presence of specific epoxi

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Synthesis And Biological Study Of Adenylyl Cyclase Inhibitors, Siyuan Sun, Zhishi Ye, Mingji Dai Aug 2014

Synthesis And Biological Study Of Adenylyl Cyclase Inhibitors, Siyuan Sun, Zhishi Ye, Mingji Dai

The Summer Undergraduate Research Fellowship (SURF) Symposium

Adenylyl cyclases (AC) is a critical family of enzymes which modulates the dynamic cellular level of cAMP, cyclic adenosine monophosphate. The study of cAMP showed that it is indispensable for the signal transduction cascades during many physiological processes, such as immune responses and metabolism which highly relate to cancers. Previous studies of AC inhibitors have been limited due to a lack of isoform-selective small molecule modulators. Selectivity of the molecules is imperative to the activation of only the desired AC inhibitor. The design of the described project was to test the structure activity relationship (SAR) by synthesizing a class of …

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Biosentinel: Monitoring Dna Damage Repair Beyond Low Earth Orbit On A 6u Nanosatellite, Brian Lewis, Robert Hanel, Sharmila Bhattacharya, Antonio Ricco, Elwood Agasid, Debra Reiss-Bubenheim, Tore Straume, Macarena Parra, Travis Boone, Sergio Santa Maria, Ming Tan, Robert Bowman, Matthew Sorgenfrei, Matthew Nehrenz, Marina Gandlin, Terry Lusby, Vanessa Kuroda, Craig Pires, Abraham Rademacher, Joshua Benton, Shang Wu, Benjamin Klamm, Charles Friedericks, Colleen Hake, Bobbie Gail Swan, Edward Semones, Scott Wheeler, C. Mark Ott, Susan Gavalas, Sarah Castro Aug 2014

Biosentinel: Monitoring Dna Damage Repair Beyond Low Earth Orbit On A 6u Nanosatellite, Brian Lewis, Robert Hanel, Sharmila Bhattacharya, Antonio Ricco, Elwood Agasid, Debra Reiss-Bubenheim, Tore Straume, Macarena Parra, Travis Boone, Sergio Santa Maria, Ming Tan, Robert Bowman, Matthew Sorgenfrei, Matthew Nehrenz, Marina Gandlin, Terry Lusby, Vanessa Kuroda, Craig Pires, Abraham Rademacher, Joshua Benton, Shang Wu, Benjamin Klamm, Charles Friedericks, Colleen Hake, Bobbie Gail Swan, Edward Semones, Scott Wheeler, C. Mark Ott, Susan Gavalas, Sarah Castro

Small Satellite Conference

We are designing and developing a “6U” nanosatellite as a secondary payload to fly aboard NASA’s Space Launch System (SLS) Exploration Mission (EM) 1, scheduled for launch in late 2017. For the first time in over forty years, direct experimental data from biological studies beyond low Earth orbit (LEO) will be obtained during BioSentinel’s 12 to 18-month mission. BioSentinel will measure the damage and repair of DNA in a biological organism and compare that to information from onboard physical radiation sensors. This data will be available for validation of existing models and for extrapolation to humans. The BioSentinel experiment will …

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Stochastic Data Assimilation Approaches For Magnetic Resonance Temperature Imaging, Joshua P. Yung Aug 2014

Stochastic Data Assimilation Approaches For Magnetic Resonance Temperature Imaging, Joshua P. Yung

Dissertations and Theses (Open Access)

During magnetic resonance (MR)-guided thermal therapies, proton resonance frequency shift (PRFS) based MR temperature imaging can quantitatively monitor tissue temperature changes. It is widely known that the PRFS technique is easily perturbed by tissue motion, tissue susceptibility changes, magnetic field drift, and modality–dependent applicator induced artifacts. Due to recent advances in computational algorithms and hardware, much more powerful statistical analysis methods are becoming realizable in the real-time processing environment. To this end, my dissertation research focused on the development, validation, and implementation of stochastic data-driven processing techniques to increase the robustness of MR temperature monitoring during thermal therapies. MR temperature …

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Passivation And Functionalization Of Conjugated Polymer Nanoparticles With Head Group Modified Phospholipids And Proteins, Prakash Kandel Aug 2014

Passivation And Functionalization Of Conjugated Polymer Nanoparticles With Head Group Modified Phospholipids And Proteins, Prakash Kandel

All Dissertations

Conjugated polymer nanoparticles (CPNs) possess important characteristics such as high fluorescence brightness, reasonable photostability, and non-toxicity. These properties allow the use of CPNs in fluorescence based cellular and biological applications including cellular labeling, imaging, biosensing, and single particle tracking. To realize the broad applications of CPNs, it is required that CPNs possess functionality to conjugate a recognition moiety and maintain colloidal stability in biological media. In the following Dissertation, we have prepared functionalized CPNs by surface passivation with head group- functionalized poly (ethylene glycol) lipids and proteins. We studied the colloidal stability of CPNs in biological media and investigated their …

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Gladys-On-The-Prairie: The Effect Of Social And Environmental Forces On The Identity And Life Of Dr. Gladys C. Galligar, Desiree M.E. King Aug 2014

Gladys-On-The-Prairie: The Effect Of Social And Environmental Forces On The Identity And Life Of Dr. Gladys C. Galligar, Desiree M.E. King

Electronic Theses & Dissertations

Twentieth century Americans recognized problems created by both the subjected status women held by society and the harmful impact humanity had on natural resources and domains. America’s search for realization and solutions for the inherent problems associated with the devaluation of women and nature did not come quickly or easily; it took a path that wound around both traditional concepts and progressive insights. I argue in this thesis that the biography of Dr. Gladys C. Galligar demonstrates, on an intimate level, America’s dawning awareness of the necessity of a healthier environment and a more egalitarian society. As a biology researcher …

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Analyses Of 2002-2013 China’S Stock Market Using The Shared Frailty Model, Chao Tang Aug 2014

Analyses Of 2002-2013 China’S Stock Market Using The Shared Frailty Model, Chao Tang

Electronic Theses and Dissertations

This thesis adopts a survival model to analyze China’s stock market. The data used are the capitalization-weighted stock market index (CSI 300) and the 300 stocks for creating the index. We define the recurrent events using the daily return of the selected stocks and the index. A shared frailty model which incorporates the random effects is then used for analyses since the survival times of individual stocks are correlated. Maximization of penalized likelihood is presented to estimate the parameters in the model. The covariates are selected using the Akaike information criterion (AIC) and the variance inflation factor (VIF) to avoid …

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Mouse Models Of Neuroanatomical, Behavioral, And Genetic Correlates Of Language-Related Impairments: An Investigation Of Core Phenotypes., Dongnhu Truong Jul 2014

Mouse Models Of Neuroanatomical, Behavioral, And Genetic Correlates Of Language-Related Impairments: An Investigation Of Core Phenotypes., Dongnhu Truong

Doctoral Dissertations

The development of the brain is an immensely complicated process that is highly regulated by numerous genetic pathways. Disruption within any stage of this operation—from proliferation, to neuronal migration, to synaptogenesis—could ultimately lead to deleterious behavioral outcomes, ranging from severe intellectual disability and gross motor developmental delays to more subtle cognitive impairments such as language disability. It is therefore no surprise that neuroanatomical anomalies resulting from of altered cortical development are associated with a number of language related neurodevelopmental disorders such as specific language impairment (SLI), dyslexia, and autism spectrum disorders (ASD). Over the past decade, genetic association studies have …

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Mary Murphy, Mary Murphy '78, Abigail Szunyogh 2014 Jul 2014

Mary Murphy, Mary Murphy '78, Abigail Szunyogh 2014

All oral histories

Mary Murphy majored in Biology with a pre-professional Medical school focus. She was the first in her immediate family to go to college. Murphy recalls faculty relationships and teaching assistant responsibilities and shares impressions about campus culture. She also mentions extracurricular activities such as church choir and the Homecoming planning committee. Dr. Murphy is a pediatrician in Ohio.

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Molecular And Functional Identification Of A Mitochondrial Ryanodine Receptor In Neurons., Regina Jakob, Gisela Beutner, Virendra K Sharma, Yuntao Duan, Robert A Gross, Stephen Hurst, Bong Sook Jhun, Jin O-Uchi, Shey-Shing Sheu Jul 2014

Molecular And Functional Identification Of A Mitochondrial Ryanodine Receptor In Neurons., Regina Jakob, Gisela Beutner, Virendra K Sharma, Yuntao Duan, Robert A Gross, Stephen Hurst, Bong Sook Jhun, Jin O-Uchi, Shey-Shing Sheu

Department of Medicine Faculty Papers

Mitochondrial Ca(2+) controls numerous cell functions, such as energy metabolism, reactive oxygen species generation, spatiotemporal dynamics of Ca(2+) signaling, cell growth and death in various cell types including neurons. Mitochondrial Ca(2+) accumulation is mainly mediated by the mitochondrial Ca(2+) uniporter (MCU), but recent reports also indicate that mitochondrial Ca(2+)-influx mechanisms are regulated not only by MCU, but also by multiple channels/transporters. We previously reported that ryanodine receptor (RyR), which is a one of the main Ca(2+)-release channels at endoplasmic/sarcoplasmic reticulum (SR/ER) in excitable cells, is expressed at the mitochondrial inner membrane (IMM) and serves as a part of the Ca(2+) …

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Methods And Materials For Stimulating Proliferation Of Stem Cells (Div), Sudipta Seal, Kiminobu Sugaya Jul 2014

Methods And Materials For Stimulating Proliferation Of Stem Cells (Div), Sudipta Seal, Kiminobu Sugaya

UCF Patents

Disclosed herein are methods and materials for influencing proliferation of stem cells. Specifically exemplified herein are compositions comprising cerium oxide nanoparticles which can be used to stimulate proliferation of stem cells under common culture conditions, or which can be utilized to improve therapeutic outcomes.

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Math Biology History Alumni Named 2014 Woodrow Wilson Teaching Fellows, Ohio University College Of Arts & Sciences Jul 2014

Math Biology History Alumni Named 2014 Woodrow Wilson Teaching Fellows, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

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Biophysical Interactions In The Straits Of Florida: Turbulent Mixing Due To Diel Vertical Migrations Of Zooplankton, Cayla Whitney Dean Jul 2014

Biophysical Interactions In The Straits Of Florida: Turbulent Mixing Due To Diel Vertical Migrations Of Zooplankton, Cayla Whitney Dean

HCNSO Student Theses and Dissertations

Diel vertical migrations (DVM) comprise the largest animal migration on the planet and are a phenomenon present in all bodies of water on Earth. A strong sound scattering layer undergoing DVM was observed in the Straits of Florida via a bottom-mounted Acoustic Doppler current profiler (ADCP) Workhorse Longranger 75 kHz (Teledyne RD Instruments) located at the 244 m isobath. ADCP average backscatter showed a clear periodicity corresponding with sunrise and sunset times indicating the presence of a nocturnal DVM. Analysis of the ADCP backscatter data indicated zooplankton swimming velocities were faster during sunrise than sunset times. In several cases the …

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Nanostructured Aluminum Oxide (Nao): Enhanced Fluorescence Imaging And Sensing, Xiang Li Jul 2014

Nanostructured Aluminum Oxide (Nao): Enhanced Fluorescence Imaging And Sensing, Xiang Li

Doctoral Dissertations

A new fluorescence enhancement technical platform based on nanostructured aluminum oxide (NAO) has been discovered. Experiments reveal that this new platform can enhance the fluorescence signals up to two or three orders of magnitude compared to a traditional glass substrate platform. In order to realize a large-scale arrayed fluorescence biosensing platform for high throughput applications, a rapid and cost-effective process has been developed to fabricate the micropatterned NAO of a variety of shapes. An optical characterization technology, by introducing UV light irradiance, has been found for the first time to determine if the NAO has been formed from Al and …

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Abolishing Exclusive Jurisdiction In The Federal Circuit: A Response To Judge Wood, Rochelle C. Dreyfus Jul 2014

Abolishing Exclusive Jurisdiction In The Federal Circuit: A Response To Judge Wood, Rochelle C. Dreyfus

Chicago-Kent Journal of Intellectual Property

Part of a symposium of responses to Chief Judge Wood’s suggestion for giving regional circuits a share of the Federal Circuit’s authority over patent law, this article argues that now that a degree of nationwide uniformity in patent law has been achieved, it would be a pity to disrupt it. While Chief Judge Wood is right that the law would improve with percolation, a change in the composition of the court, new procedures for challenging patents in the Patent and Trademark Office, a District Court pilot program, and satellite patent offices will bring to the debate new voices, different kinds …

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