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State-Centric Or State-In-Society: National Identity And Collective Memory In The Linkage Politics Of Chinese Foreign Relations, Ning Liao
Graduate Program in International Studies Theses & Dissertations
This dissertation, with a standpoint of disentangling China's diplomacy "inside-out," explores the Chinese state-society relationship in domestic-foreign-policy interaction. With its analytic focus resting on the collective memory of national humiliation in modern Chinese history and the derived national identity, this project delves into the linkage between the ideational impetus of the diplomatic decision-making of the Chinese Communist Party (CCP) and the way that the authoritarian regime claims its internal and external legitimacy.
In the state legitimation, collective memory and national identity are instrumentalized to enact the moral justification of the CCP's political authority and to justify China's persistent quest to …
Enabling Local Solutions To Global Problems: The Role Of Cultural Intelligence In Building Global Sof Networks, Emily Spencer
Enabling Local Solutions To Global Problems: The Role Of Cultural Intelligence In Building Global Sof Networks, Emily Spencer
Journal of Strategic Security
In order to provide regional solutions to potentially world-wide problems, global special operations forces (SOF) networks maximize the benefits of SOF, in particular, their aptitude and ability to perform in a culturally intelligent manner. Indeed, to be able to facilitate regional solutions to potentially global problems, SOF need to exhibit high levels of cultural intelligence, which requires an understanding of culture combined with an ability to apply strategic thinking. By being able to address issues critically and creatively – the hallmarks of strategic thinking – while understanding and behaving appropriately in a variety of cultural contexts, SOF, acting within global …
Student-Directed Blended Learning With Facebook Groups And Streaming Media: Media In Asia At Furman University, Tami Blumenfield
Student-Directed Blended Learning With Facebook Groups And Streaming Media: Media In Asia At Furman University, Tami Blumenfield
Asian Studies Publications
Furman University prizes itself on being an engaged learning, liberal arts institution with extensive faculty-student interaction. 96% of students live on campus, leading some to question whether reducing face-to-face instructional time makes any sense pedagogically. Coming from a different institution that encouraged faculty to create hybrid courses, and seeing the creativity and freedom that offered, I wanted to experiment with the format in this new institutional environment. Would it still be effective? What adaptations would be necessary, and how would students react to this different course format?
In Fall 2013, I taught a carefully designed blended learning course that met …
Openline Newsletter, July 2014, Civil Service Council
Openline Newsletter, July 2014, Civil Service Council
OpenLine Newsletter
A monthly newsletter for Civil Service employees, Volume 39, Number 1, July 2014.
Contracts Symposium Issue: Featured Speaker: The Right To Contract As A Civil Right, Robin West
Contracts Symposium Issue: Featured Speaker: The Right To Contract As A Civil Right, Robin West
Georgetown Law Faculty Publications and Other Works
The "right to contract," whether originating in the Constitution, common law, or natural law, has been long and widely felt to be in tension with our civil rights, broadly conceived. The individual himself, we generally believe, and only the individual, should decide the scope and terms of his affirmative, voluntary, and other-regarding undertakings. When he does so through contract, the individual and only the individual should determine the terms under which he will perform those duties. The civil rights laws of the nineteenth, twentieth, and early twenty-first centuries, and the various rights they create interfere with these natural freedoms.
So, …
A Cross-National Analysis Of The Impact Of Conscription On Crime Rates, Nicolette G. Rose
A Cross-National Analysis Of The Impact Of Conscription On Crime Rates, Nicolette G. Rose
Sociology & Criminal Justice Theses & Dissertations
This paper examines the relationship between conscription laws (mandatory military or social service) and crime rates across countries. This cross-national study focuses on three major crimes: burglary, robbery, and homicide. In addition to conscription laws several control variables have been included in the analyses are: percent of the labor force that is military, level of civil liberties/freedom, level of industrialization, illiteracy rates, percent of urban population, unemployment rates, percent under the international poverty line, income disparity (measured using the Gini index), and population.
This study assesses the impact of conscription on crime rates by formulating and testing three hypotheses. First, …
Death On Display: Understanding The Publicized Eulogies Of African American Cultural Figures As An Empowering Rhetorical Discourse, Melody Shelton Williams
Death On Display: Understanding The Publicized Eulogies Of African American Cultural Figures As An Empowering Rhetorical Discourse, Melody Shelton Williams
English Theses & Dissertations
This dissertation names and identifies the African American Eulogic Tradition as a specific custom within Black culture in the U.S. that originated during slavery and resulted from a fusion of West African burial traditions and Protestant Christianity. The emergence of the Black Church as an influential social institution led by free Blacks cemented the use of funerary practices to support and preserve the bonds of community. This project explores how modern eulogists collectively empower African American audiences through their delivery of Eulogic oratory by analyzing the contextual framework and rhetorical modes of eulogies delivered for Whitney Houston, James Brown, Michael …
Selling "Kawaii" In Advertising: Testing Cross-Cultural Perceptions Of Kawaii Appeals, Tao Deng
Selling "Kawaii" In Advertising: Testing Cross-Cultural Perceptions Of Kawaii Appeals, Tao Deng
Master's Theses (2009 -)
"Kawaii" (cute) culture has become a major global consumer culture. Advertisers in Asia have adopted kawaii appeals to attract attention and promote product images. From a cultural value perspective, this literature review proposes that culture not only affects ad content and appeal, but also influences consumer attitude and ad effects. While kawaii appeals are culturally specified, the effects of those appeals across distinct cultures might be systemically predictable. Today, the concept of kawaii and its effects still remains vague to Western academia. This thesis provides a deeper understanding of kawaii examining the rich origin of kawaii culture in Japan and …
Comparing The Vertical Misfit Of Casts Produced By Two Verification Jigs, Abdulaziz Saeed Alqahtani
Comparing The Vertical Misfit Of Casts Produced By Two Verification Jigs, Abdulaziz Saeed Alqahtani
Master's Theses (2009 -)
Purpose: To compare the dimensional accuracy between master casts fabricated with verification jigs made of acrylic resin and light cure Triad. Materials and Methods: 10 GC Pattern resin Pattern verifications jigs and 10 Triad gel verification jigs fabricated of a master cast of a mandibular model of 4 internal hex implants. A stone base was fabricated for each verification jig. One screw test was used to evaluate the vertical gap at the terminal abutment using a digital micrometer with an accuracy of 1μm to record the vertical gap for each sample. Results: Triad Gel group has the lowest average distortion …
A Comprehensive Evaluation Of C25 Highly Branched Isoprenoid Alkenes Of Marine Diatoms As Proxies For Sea Ice Extent In The Arctic Ocean, Tetiana Muniak
A Comprehensive Evaluation Of C25 Highly Branched Isoprenoid Alkenes Of Marine Diatoms As Proxies For Sea Ice Extent In The Arctic Ocean, Tetiana Muniak
OES Theses and Dissertations
Sea Ice extent is one of the major factors regulating carbon cycling and ecosystem function in the modern Arctic Ocean. It is an essential component of climate models and is crucial for the evaluation of various oceanographic processes that influence a particular region. Yet it is also one of the most difficult attributes of the ocean with respect to our ability for its accurate reconstruction from paleo records. The lack of the detailed records prior to satellite information has encouraged the development of new proxy records for the reconstruction of past
sea ice conditions. In recent years, a new monounsaturated …
Health Promotion Strategies Derived From A Metropolitan Police Weight Loss Competition With Weight Loss Comparisons By Gender And Bmi Category, Robert Boyce, Tyler Willett, Allen Mullins, Glenn Jones, Randy Cottrell
Health Promotion Strategies Derived From A Metropolitan Police Weight Loss Competition With Weight Loss Comparisons By Gender And Bmi Category, Robert Boyce, Tyler Willett, Allen Mullins, Glenn Jones, Randy Cottrell
Internet Journal of Allied Health Sciences and Practice
Background: Weight management is critical in police work. It can have both legal and life-saving implications as it is linked to the health and physical readiness of the officers. A weight loss competition is one way to address weight management in police work. Among the factors to consider is gender impact, as females forge forward within a male environment. Also, assessing weight loss among obesity categories is essential for designing effective programing. Purpose: To compare mass changes among body mass index (BMI) categories and between genders at biweekly weigh-ins during a 12-week competition with recommendations for professionals. Methods: Before the …
A Position Analysis Of Coupled Spherical Mechanisms In Action Origami, Landen A. Bowen, L. A. Baxter, Spencer P. Magleby, Larry L. Howell
A Position Analysis Of Coupled Spherical Mechanisms In Action Origami, Landen A. Bowen, L. A. Baxter, Spencer P. Magleby, Larry L. Howell
Faculty Publications
Origami has been previously utilized in design to create deployable systems. Action origami, origami designed to move, has the ability to deploy to a larger state and have motion in the deployed state. The majority of action origami achieves motion through coupled systems of spherical mechanisms. An origami vertex, the point at which folds converge, is shown to be equivalent to a spherical change-point mechanism. A position analysis of an origami vertex is presented, resulting in a relationship between input and output angles as well as the path of the coupler link. A method for analyzing coupled systems of repeated …
The Born Approximation, Multiple Scattering, And The Butterfly Algorithm, Alejandro F. Martinez
The Born Approximation, Multiple Scattering, And The Butterfly Algorithm, Alejandro F. Martinez
Theses and Dissertations - UTB/UTPA
Radar works by focusing a beam of light and seeing how long it takes to reflect. To see a large region the beam is pointed in different directions. The focus of the beam depends on the size of the antenna (called an aperture). Synthetic aperture radar (SAR) works by moving the antenna through some region of space. A fundamental assumption in SAR is that waves only bounce once. Several imaging algorithms have been designed using that assumption. The scattering process can be described by iterations of a badly behaving integral. Recently a method for efficiently evaluating these types of integrals …
Studies Of A Mathematical Model For Generating Rhythmic Behavior With A Simple Brain, Juan C. Morales
Studies Of A Mathematical Model For Generating Rhythmic Behavior With A Simple Brain, Juan C. Morales
Theses and Dissertations - UTB/UTPA
The rhythmic behavior of feeding in the pond snail, Lymnaea stagnalis can be described computationally by a model describing its central pattern generator network (CPG). The model includes coupled Hodgkin-Huxley type nonlinear ordinary differential equations describing four neurons connected by both inhibitory and excitatory synapses. We studied the system’s dependence on current parameters to generate periodic behavior. We also considered the effect of eliminating specific connections from the network. In addition, experiments on the biological system were used to motivate application of the model in Parkinson’s disease.
The Ecological Impact Of Casitas On Caribbean Spiny Lobster (Panulirus Argus) Populations In The Florida Keys, Fl, (Usa), Benjamin C. Gutzler
The Ecological Impact Of Casitas On Caribbean Spiny Lobster (Panulirus Argus) Populations In The Florida Keys, Fl, (Usa), Benjamin C. Gutzler
Biological Sciences Theses & Dissertations
Casitas are artificial structures placed on the seabed by fishermen to aggregate Caribbean spiny lobsters (Panulirus argus) for ease of capture. Some researchers suggest that they may also enhance lobster populations in shelter-limited environments. Conversely, aggregation of lobsters within casitas may be detrimental to the population if the nutritional condition or mortality of lobsters is poorer in casitas than in natural shelters. Small juvenile lobsters may be at particular risk because their foraging range is smaller and they are more readily preyed upon than larger lobsters. If so, then casitas placed in lobster nurseries may function as "ecological traps"; wherein …
At The Unmaking, Wendi Ellen White
At The Unmaking, Wendi Ellen White
English Theses & Dissertations
This collection of poetry explores the multiple tipping points facing humanity at the opening of the 21st century and the end of the industrial age. Resource depletion, species loss and global warming are just a few of the existential threats examined in this work. I believe that the way beyond these crises requires examining the narratives we're inherited and imagining new tales of people, place and planet that can deliver us to a more ecologically just future. This thesis is an offering toward that end. At the Unmaking is a lament for what we have lost and are losing. …
Pharmacokinetic Characterization Of Procoagulation Proteins, Nicholas C. Vanderslice
Pharmacokinetic Characterization Of Procoagulation Proteins, Nicholas C. Vanderslice
Department of Chemical and Biomolecular Engineering: Dissertations, Theses, and Student Research
The cessation of bleeding in mammals occurs due to a well-conserved sequence of protein activation known as the coagulation cascade. However, people who have a deficiency in one or more proteins in this cascade, whether due to genetics or blood loss, struggle to maintain hemostasis. In order to aid patients in the restoration of hemostasis, exogenous proteins are often administered in response to bleeding events. However, these proteins are limited and costly due to limited supply of donor blood available for the production of plasma-derived proteins and the high cost of mammalian cell bio-reactors required for the production of recombinant …
A Coordinated Effort To Manage Soybean Rust In North America: A Success Story In Soybean Disease Monitoring, E. J. Sikora, T. W. Allen, K. A. Wise, G. Bergstrom, C. A. Bradley, J. Bond, D. Brown-Rytlewski, M. Chilvers, J. Damicone, E. Dewolf, Ohio State University Dorrance, N. Dufault, P. Esker, T. R. Faske, L. Giesler, N. Goldberg, J. Golod, I. R. G. Gomez, C. Grau, A. Grybauskas, G. Franc, R. Hammerschmidt, G. L. Hartman, R. A. Henn, D. Hershman, C. Hollier, T. Isakeit, S. Isard, B. Jacobsen, D. Jardine, R. Kemerait, S. Koenning, M. Langham, D. Malvick, S. Markell, J. J. Marois, S. Monfort, D. S. Mueller, J. Mueller, R. Mulrooney, M. Newman, L. Osborne, G. B. Padgett, B. E. Ruden, J. Rupe, R. Schneider, H. Schwartz, G. Shaner, S. Singh, E. Stromberg, L. Sweets, A. Tenuta, S. Vaiciunas, X. B. Yang, H. Young-Kelly, J. Zidek
A Coordinated Effort To Manage Soybean Rust In North America: A Success Story In Soybean Disease Monitoring, E. J. Sikora, T. W. Allen, K. A. Wise, G. Bergstrom, C. A. Bradley, J. Bond, D. Brown-Rytlewski, M. Chilvers, J. Damicone, E. Dewolf, Ohio State University Dorrance, N. Dufault, P. Esker, T. R. Faske, L. Giesler, N. Goldberg, J. Golod, I. R. G. Gomez, C. Grau, A. Grybauskas, G. Franc, R. Hammerschmidt, G. L. Hartman, R. A. Henn, D. Hershman, C. Hollier, T. Isakeit, S. Isard, B. Jacobsen, D. Jardine, R. Kemerait, S. Koenning, M. Langham, D. Malvick, S. Markell, J. J. Marois, S. Monfort, D. S. Mueller, J. Mueller, R. Mulrooney, M. Newman, L. Osborne, G. B. Padgett, B. E. Ruden, J. Rupe, R. Schneider, H. Schwartz, G. Shaner, S. Singh, E. Stromberg, L. Sweets, A. Tenuta, S. Vaiciunas, X. B. Yang, H. Young-Kelly, J. Zidek
Department of Plant Pathology: Faculty Publications
Existing crop monitoring programs determine the incidence and distribution of plant diseases and pathogens and assess the damage caused within a crop production region. These programs have traditionally used observed or predicted disease and pathogen data and environmental information to prescribe management practices that minimize crop loss (3,69). Monitoring programs are especially important for crops with broad geographic distribution or for diseases that can cause rapid and great economic losses. Successful monitoring programs have been developed for several plant diseases, including downy mildew of cucurbits, Fusarium head blight of wheat, potato late blight, and rusts of cereal crops (13,36,51,80).
State Litigation During The Obama Administration: Diverging Agendas In An Era Of Polarized Politics, Paul Nolette
State Litigation During The Obama Administration: Diverging Agendas In An Era Of Polarized Politics, Paul Nolette
Political Science Faculty Research and Publications
Throughout the Obama Administration, state attorneys general (AGs) have collaborated on several high-profile political issues. To get a fuller picture of this contemporary AG activism, this article analyzes AG participation in lawsuits and amicus curiae briefs before the U.S. Supreme Court across three presidential administrations. The results suggest that AGs’ agendas have increasingly diverged throughout the Obama Administration, reflecting greater vertical conflict between AGs and the federal government as well as horizontal conflict among AGs themselves. Several factors have contributed to this development, including the broader polarization of American politics, intensified activism among Republican AGs, and increased collaborations between AGs …
A Study Of Social Capital And Its Relationship With Dwelling Structure And Environment Based On An Empirical Analysis Of Lincoln, Nebraska, Jeehoon Kim
Department of Geography: Dissertations, Theses, and Student Research
Social capital is described as the concept of social network or social interaction among residents in a neighborhood. In times past, physical environment factors enhancing the level of social capital were main issues to researchers: land-use type and neighborhood design. However, based on various benefits gained from social capital theory, it is needed to study about the influence of social capital. Thus, the impact of social capital on the physical urban environment is investigated in this dissertation research in order to make more livable, healthier, and more active community. Most researches dealing with social capital and housing condition have not …
Prairie Pines: Water For Life, A Visual Short, Steven Schubert
Prairie Pines: Water For Life, A Visual Short, Steven Schubert
Department of Environmental Studies: Undergraduate Student Theses
Oft defined by the people that inhabit it, land has taken many shapes and forms. The spiritual relationship between indigenous Native Americans and nature preserved the virgin beauty of the New World. Here, life of all kinds throve. However, this measured balance was not to be lasted. With the passing of years and advancement of human technology, social order, and insatiable desire North America was found, claimed, and sullied. European (and American) colonialism brought irreversible change to the land of the Americas. Economic emphasis on the maximization of resources defiled flora and fauna alike and interrupted thousands of years of …
A Choreography Of Living Texts: Selections From The Arst Oral History Project, Kenny Walker, Jennifer Malkowski, Damien S. Pfister
A Choreography Of Living Texts: Selections From The Arst Oral History Project, Kenny Walker, Jennifer Malkowski, Damien S. Pfister
Department of Communication Studies: Faculty Publications
Oral history projects about rhetorical studies contribute to transdisciplinary histories by creating living texts that reflect the dynamism of scholarly cultures. Through interviews conducted at the twentieth anniversary of the founding of the Association for the Rhetoric of Science and Technology (ARST), we chart the organizational and intellectual history of a field, its contributions to science studies, and its potential future directions. These digitized, archived oral histories serve as an articulation point for transdisciplinary reflection, but they also represent an important strand of digital humanities work that creates living texts and keeps them open for future articulations.
Student Engagement And Academic Achievement In Technology Enhanced And Traditional Classroom Environments, Tomeko Johnson-Smith
Student Engagement And Academic Achievement In Technology Enhanced And Traditional Classroom Environments, Tomeko Johnson-Smith
Doctoral Dissertations and Projects
The purpose of this study was to determine the extent to which student engagement and academic achievement were associated with exposure to different modes of instruction; specifically technology enhanced environments vs. traditional FACE-TO-FACE environments. A cross-sectional survey was conducted in October 2013 at a local community college in Charlotte, NC. The Class Level Survey of Student Engagement (CLASSE) was administered to collect valid and reliable variables relating to student engagement from a convenience sample consisting of 80 volunteers enrolled in the Medical Science and Science divisions. Other variables were collected using the Demographic Questionnaire, and the Instructional Environment Questionnaire. The …
The Dominance Concept Inventory: A Tool For Assessing Undergraduate Student Alternative Conceptions About Dominance In Mendelian And Population Genetics, Joel K. Abraham, Kathryn E. Perez, Rebecca M. Price
The Dominance Concept Inventory: A Tool For Assessing Undergraduate Student Alternative Conceptions About Dominance In Mendelian And Population Genetics, Joel K. Abraham, Kathryn E. Perez, Rebecca M. Price
School of Integrative Biological & Chemical Sciences (Formerly Dept. of Biology)
Despite the impact of genetics on daily life, biology undergraduates understand some key genetics concepts poorly. One concept requiring attention is dominance, which many students understand as a fixed property of an allele or trait and regularly conflate with frequency in a population or selective advantage. We present the Dominance Concept Inventory (DCI), an instrument to gather data on selected alternative conceptions about dominance. During development of the 16-item test, we used expert surveys (n = 12), student interviews (n = 42), and field tests (n = 1763) from introductory and advanced biology undergraduates at public …
Biodegradable Electrospun Nanofibers Coated With Platelet-Rich Plasma For Cell Adhesion And Proliferation, Luis Diaz-Gomez, Carmen Alvarez-Lorenzo, Angel Concheiro, Maite Silva, Fernando Dominguez, Faheem A. Sheikh, Travis Cantu, Raj Desai, Vanessa L. Garcia, Javier Macossay-Torres
Biodegradable Electrospun Nanofibers Coated With Platelet-Rich Plasma For Cell Adhesion And Proliferation, Luis Diaz-Gomez, Carmen Alvarez-Lorenzo, Angel Concheiro, Maite Silva, Fernando Dominguez, Faheem A. Sheikh, Travis Cantu, Raj Desai, Vanessa L. Garcia, Javier Macossay-Torres
School of Integrative Biological & Chemical Sciences (Formerly Dept. of Chemistry)
Biodegradable electrospun poly(ε-caprolactone) (PCL) scaffolds were coated with platelet-rich plasma (PRP) to improve cell adhesion and proliferation. PRP was obtained from human buffy coat, and tested on human adipose-derived mesenchymal stem cells (MSC) to confirm cell proliferation and cytocompatibility. Then, PRP was adsorbed on the PCL scaffolds via lyophilization, which resulted in uniform sponge-like coating of 2.85 (s.d. 0.14) mg/mg. The scaffolds were evaluated regarding mechanical properties (Young’s modulus, tensile stress and tensile strain), sustained release of total protein and growth factors (PDGF-BB, TGF-β1 and VEGF), and hemocompatibility. MSC seeded on the PRP-PCL nanofibers showed an increased adhesion and proliferation …
Knowledge And Attitude Of Healthcare Professionals Toward Medication Pregnancy Category Systems In Saudi Hospitals, Thamir M. Alshammari, Adel A. Alrwisan, Majed I. Aljeraisy, Khalid W. Taher, Faisal M. Alissa, Mansour A. Mahmoud, Mohamad A. Hassali, Hisham S. Aljadhey
Knowledge And Attitude Of Healthcare Professionals Toward Medication Pregnancy Category Systems In Saudi Hospitals, Thamir M. Alshammari, Adel A. Alrwisan, Majed I. Aljeraisy, Khalid W. Taher, Faisal M. Alissa, Mansour A. Mahmoud, Mohamad A. Hassali, Hisham S. Aljadhey
Saudi Medical Journal
OBJECTIVE: To assess the knowledge and attitudes of healthcare professionals (HCPs) toward systems used in describing the safety of medications use during pregnancy. METHODS: A cross-sectional self-administered survey was conducted in 4 tertiary hospitals in Riyadh, Saudi Arabia between March and May 2012. The targeted HCPs were physicians and pharmacists. The survey was validated and contained 4 main sections. Descriptive statistics were used to report responses to the survey9s questions. RESULTS: A total of 393 HCPs responded to the survey, with a response rate of 97%. Half of the respondents were physicians. Of the participants, 60% were males. Most respondents …
Bilateral Iliopsoas Abscess Associated With Right Hip Septic Arthritis In A Neonate, Maher M. Al-Zaiem, Salem J. Bajuifer, Mohammed O. Fattani, Feras M. Al-Zaiem
Bilateral Iliopsoas Abscess Associated With Right Hip Septic Arthritis In A Neonate, Maher M. Al-Zaiem, Salem J. Bajuifer, Mohammed O. Fattani, Feras M. Al-Zaiem
Saudi Medical Journal
Iliopsoas abscess is a very rare pathology in the neonatal period. There is a lack of reports in the literature on bilateral psoas abscess with hip joint arthritis. We report a case of bilateral iliopsoas abscess with concomitant right hip septic arthritis, caused by methicillin-resistant Staphylococcus aureus in a 28-day-old male infant. The baby presented with bilateral diffuse swelling of the groins and upper thighs. He was treated successfully by ultrasound-guided percutaneous drainage along with systemic antibiotic therapy. Clinical improvement was observed within 24-48 hours of drainage.
Observance: A Record Of Experiments, Olivia L. Mosley
Observance: A Record Of Experiments, Olivia L. Mosley
Undergraduate Theses—Unrestricted
Thesis writing on the work of Olivia Mosley, Bachelor of Fine Arts candidate in Printmaking at Washington University in St. Louis. Engaging with a diverse history of photography and observation through the theoretical writings of Barthes, Berger, Didi-Huberman and others, Mosley conducts a series of visual experiments as part of her art practice in an attempt to expand her visual knowledge. Exploring the concepts of visualization, observation and the role technology plays in both of the aforementioned activities, Mosley’s work is discussed alongside the visual contributions of scientists, artists and hobbyists experimenting with the photographic medium throughout history, including, Wilhelm …
Public Health Regulation: Convergence, Divergence, And Regulatory Tension: An Asian Perspective, Locknie Hsu
Public Health Regulation: Convergence, Divergence, And Regulatory Tension: An Asian Perspective, Locknie Hsu
Research Collection Yong Pung How School Of Law
Regulatory issues relating to public health, including regulation of access to medicines and tobacco control have increasingly been the source of tension in recent trade and investment negotiations, treaties and disputes. The ongoing Trans-Pacific Partnership negotiations, which include a number of developing Asian states, are an example that brings some of these issues to the fore and show a divergence of negotiating views.
The intersection between public health regulation and trade and investment treaties has given some Asian states significant pause for thought; it has further led the international system to a critical need to confront the overlap of legal …
Optimal Aggregation Of Fcεri With A Structurally Defined Trivalent Ligand Overrides Negative Regulation Driven By Phosphatases, Avanika Mahajan, Dipak Barua, Patrick Cutler, Diane S. Lidke, Flor A. Espinoza, Carolyn Pehlke, Rachel Grattan, Yuko Kawakami, Chang-Shung Tung, Andrew R. M. Bradbury, William S. Hlavacek, Bridget S. Wilson
Optimal Aggregation Of Fcεri With A Structurally Defined Trivalent Ligand Overrides Negative Regulation Driven By Phosphatases, Avanika Mahajan, Dipak Barua, Patrick Cutler, Diane S. Lidke, Flor A. Espinoza, Carolyn Pehlke, Rachel Grattan, Yuko Kawakami, Chang-Shung Tung, Andrew R. M. Bradbury, William S. Hlavacek, Bridget S. Wilson
Chemical and Biochemical Engineering Faculty Research & Creative Works
To investigate why responses of mast cells to antigen-induced IgE receptor (FcεRI) aggregation depend nonlinearly on antigen dose, we characterized a new artificial ligand, DF3, through complementary modeling and experimentation. This ligand is a stable trimer of peptides derived from bacteriophage T4 fibritin, each conjugated to a hapten (DNP). We found low and high doses of DF3 at which degranulation of mast cells sensitized with DNP-specific IgE is minimal, but ligand-induced receptor aggregation is comparable to aggregation at an intermediate dose, optimal for degranulation. This finding makes DF3 an ideal reagent for studying the balance of negative and positive signaling …