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The Murray Ledger And Times, December 12, 2014, The Murray Ledger And Times

The Murray Ledger & Times

No abstract provided.

Comparative Genomics Reveals Insights Into Avian Genome Evolution And Adaptation, Guojie Correction Zhang, Cai Li, Qiye Li, Bo Li, Denis M. Larkin, Chul Lee, Jay F. Storz, Agostinho Antunes, Matthew J. Greenwold, Robert W. Meredith, Anders Ödeen, Jie Cui, Qi Zhou, Luohao Xu, Hailin Pan, Zongji Wang, Lijun Jin, Pei Zhang, Haofu Hu, Wei Yang, Jiang Hu, Jin Xiao, Zhikai Yang, Yang Liu, Qiaolin Xie, Hao Yu, Jinmin Lian, Ping Wen, Fang Zhang, Hui Li, Yongli Zeng, Zijun Xiong, Shiping Liu, Long Zhou

Faculty Publications

Birds are the most species-rich class of tetrapod vertebrates and have wide relevance across many research fields. We explored bird macroevolution using full genomes from 48 avian species representing all major extant clades. The avian genome is principally characterized by its constrained size, which predominantly arose because of lineage-specific erosion of repetitive elements, large segmental deletions, and gene loss. Avian genomes furthermore show a remarkably high degree of evolutionary stasis at the levels of nucleotide sequence, gene synteny, and chromosomal structure. Despite this pattern of conservation, we detected many non-neutral evolutionary changes in protein-coding genes and noncoding regions. These analyses …

Whole-Genome Analyses Resolve Early Branches In The Tree Of Life Of Modern Birds, Erich D. Jarvis, Siavash Mirarab, Andre J. Aberer, Bo Li, Peter Houde, Cai Li, Simon Y.W. Ho, Brant C. Faircloth, Benoit Nabholz, Jason T. Howard, Alexander Suh, Claudia C. Weber, Rute R. Da Fonseca, Jianwen Li, Fang Zhang, Hui Li, Long Zhou, Nitish Narula, Liang Liu, Ganesh Ganapathy, Bastien Boussau, Md Shamsuzzoha Bayzid, Volodymyr Zavidovych, Sankar Subramanian, Toni Gabaldón, Salvador Capella-Gutiérrez, Jaime Huerta-Cepas, Bhanu Rekepalli, Kasper Munch, Mikkel Schierup, Bent Lindow, Wesley C. Warren, David Ray, Richard E. Green

Faculty Publications

To better determine the history of modern birds, we performed a genome-scale phylogenetic analysis of 48 species representing all orders of Neoaves using phylogenomic methods created to handle genome-scale data.We recovered a highly resolved tree that confirms previously controversial sister or close relationships.We identified the first divergence in Neoaves, two groups we named Passerea and Columbea, representing independent lineages of diverse and convergently evolved land and water bird species. Among Passerea, we infer the common ancestor of core landbirds to have been an apex predator and confirm independent gains of vocal learning. Among Columbea, we identify pigeons and flamingoes as …

Does Thorium Have A Place In The Future U.S. Electricity Mix?, Danny West

Master's Projects and Capstones

Thorium is an alternative fuel source for nuclear energy. Coupled with its use in a new reactor design, called a Liquid Fluoride Thorium Reactor, the two have the ability to disrupt the nuclear industry and power sector. Nuclear energy is a clean and reliable source of energy; however, it generates hazardous waste that must be stored away for hundreds of thousands of years and power plants are at risk of a catastrophic incident that can lead to a wide scale release of radiation. These drawbacks to nuclear energy can be mitigated using thorium in a Liquid Fluoride Thorium Reactor. These …

Launching A Virtual Decision Lab: Development And Field-Testing Of A Web-Based Patient Decision Support Research Platform, Aubri S. Hoffman, Hilary A. Llewellyn-Thomas, Anna N. A. Tosteson, Annette M. Oconnor

Dartmouth Scholarship

Over 100 trials show that patient decision aids effectively improve patients’ information comprehension and values-based decision making. However, gaps remain in our understanding of several fundamental and applied questions, particularly related to the design of interactive, personalized decision aids. This paper describes an interdisciplinary development process for, and early field testing of, a web-based patient decision support research platform, or virtual decision lab, to address these questions.

Creating Theatre-Based Curriculum For Use In The Esl/Efl Language Classroom: A Model, Alexandra Williams-Fleck

Master's Projects and Capstones

Many countries require the study of the English language as part of the standard curriculum in K-12 schools. Unfortunately, many students lack the interest and motivation to learn, despite English’s potential to open future academic and professional doors. This is particularly true for students living in countries where English is not a nationally spoken language. They receive no language support from their surrounding environment, which affects their rate of language acquisition. Coupled with a prevalence of out-of-context materials and non-native English-speaking teachers (NNESTs) who may be unable to impart the non-verbal and cultural implications of the language, students are at …

The Geology And Petrology Of Enigmatic Rhyolites At Graveyard And Gordon Buttes, Mount Hood Quadrangle, Oregon, Elizabeth G. Westby

Dissertations and Theses

Rhyolite lava flows are found at two dome complexes at Graveyard Butte and Gordon Butte, Mount Hood Quadrangle, Oregon. At Graveyard Butte, the White River has cut a winding canyon 150 m deep, exposing at its base, a 40-meter-thick outcrop of flow-banded rhyolite (73 wt.% SiO₂, 3.67±0.01 Ma) that laterally extends along the canyon wall for about 1 km. Stratigraphically above the flow-banded rhyolite is locally-erupted iron-rich andesites (lava flows, agglutinate and other pyroclastic rocks as well as clastic debris), a rhyolitic ash-flow tuff (74 wt.% SiO₂), and the 2.77±0.36 Ma tholeiitic basalt lava flows of …

Into The Red: A Look Into The Reasons Why Refugees Decide To Flee, Settle Or Migrate To And From Morocco, Fadeelah E. Holivay

Master's Theses

This research paper explores some of the main reasons why refugees and asylum seekers, particularly from sub-Saharan African countries, embark on a journey and decide to settle, flee or migrate to and from Morocco. Because of this phenomenon, Morocco has seen a 96% increase of refugees migrating to the borders of Morocco each year for the past three years. Many say that this astonishing increase of migrants choosing Morocco is due to such factors as: wars breaking out regionally across central African and Middle Eastern countries causing them to flee; Morocco being a culturaly diverse francophone country whose laws and …

The Bg News December 12, 2014, Bowling Green State University

BG News (Student Newspaper)

The BGSU campus student newspaper. December 12, 2014. Volume 94-Issue 47.

How Disgust Affects Romantic Attraction: How Our Moods Affect Our Judgments Of Attractiveness, Nicholas Phelan

Theses

Facial attractiveness is an important part of our initial judgments of people and in our ability to determine their compatibility as a mating partner. Just as mating is evolutionarily important, the emotion disgust is one of the most evolutionarily beneficial emotions as it helps keep us away from poisonous and possibly infectious substances or foods. We instinctively avoid people with facial scars and other facial deformities because these are seen as a sign of illness or generally poor well-being. Facial attraction is one component of how we choose a mate. The current experiment examined whether or not being disgusted created …

Exhibition, Featuring, Catherine Duggan

Master's Theses

Exhibition, Featuring is a collection of poems inspired by art, life, and history intertwined with the very center of humanness, convergence of heart and brain. The poems assembled here attempt to recreate the sensation of memory and remembering, and at times, trying to forget. Concerned with language and the ways in which we communicate with others, the lines weave in and out of conversation, evoking daily interac­tions and thoughts carried within us, continuous as breathing. The collection is divided into five parts, each establishing a variance of the whole—all parts a harmony. The reader will discover formal poetry, poems evoking …

Ancestral Variation And The Evolution Of Sneaking Behavior In The Adaptive Radiation Of Threespine Stickleback (Gasterosteus Aculeatus L.), Katherine A. Shaw

Doctoral Dissertations

Behavior, a group of highly plastic and responsive phenotypic traits, has been characterized as having the potential to both drive and inhibit evolutionary change within populations. The Threespine Stickleback radiation (Gasterosteus aculeatus L.) is a model system that demonstrates the vital role environment plays in behavioral evolution – with multiple colonizations of variable freshwater habitats by ancestral oceanic metapopulations producing the behaviorally diverse populations observable today. Here I characterize both inter- and intra-population variation in sneaking behavior – an inconspicuous mating tactic used by threespine males to gain fertilizations as an alternative to courtship behavior. I present evidence for …

The Effect Of Topical Estriol On Human Inner Foreskin, Cheryl L. Bell

Doctoral Dissertations

Human immunodeficiency virus (HIV) is a global health concern prompting an urgent need to develop simple, effective, economical preventive measures. The research described in this thesis evaluated the potential for topical estriol to induce keratinization of the inner foreskin, the primary site of HIV entry in uncircumcised males.

We found that topical estriol can induce keratinization of the human inner foreskin by up-regulating the production of keratins per cell, and not through increased skin proliferation. Furthermore, the quantity and position of HIV target cells in the foreskin were not adversely affected by the treatment.

Estrogen receptors (ERs) are transcription factors …

Freshwater Transitions And The Evolution Of Osmoregulation In The Alewife, Jonathan P. Velotta

Doctoral Dissertations

The transition from seawater to freshwater is deeply rooted in the evolutionary history of animals, initiating the radiation and speciation of many taxa. However, crossing the boundary into freshwater from the sea represents a considerable physiological challenge for animals that maintain a near constant internal ion concentration. Because seawater and freshwater differ strongly in solute concentration, the transition into freshwater must involve the evolution of ion and water balance; yet, we have a limited understanding of the physiological modifications that facilitate this transition. Here, I investigate the evolution of the osmoregulatory system upon transition to freshwater using populations of an …

Mythological Rewriting: New Perspectives On Algeria's Postcolonial History, Elena Telegina

Doctoral Dissertations

Mythological Rewriting: New Perspectives on Algeria’s Postcolonial History.

Elena Telegina, Ph.D

University of Connecticut [2014]

Abstract

Algerian history, falsified and distorted by different Algerian regimes, obscured the nature of many contemporary problems, while creating a climate of confusion about the present and anxiety about the future. Beneath Algeria’s relative calm during the uprisings of the “Arab Spring”, violence and social dissociation, continue to threaten the society, showing that deep-seated historical conflicts in Algeria remain unsolved.

While historians and political scientists attempt to clarify the contemporary situation from a scientific perspective, Francophone Algerian novelists have addressed these issues by drawing on …

Clean Up Techniques Used For Coastal Oil Spills: An Analysis Of Spills Occurring In Santa Barbara, California, Prince William Sound, Alaska, The Sea Of Japan, And The Gulf Coast, Henry R. Walther Iii

Master's Projects and Capstones

An analysis of four spills occurring within the last 50 years to see the progression in clean up techniques used for coastal oil spills. The Santa Barbara, California Oil Spill of 1969, the Exxon Valdez Oil Spill of 1989 occurring in Prince William Sound, Alaska, the Nakhodka Oil Spill of 1997 occurring in the Sea of Japan, and the Deep Water Horizon Oil spill of 2010 occurring in the Gulf of Mexico, are analyzed. The different types of oil, the composition of oil, and the variables that effect spilled oil’s movement, are provided. Oil spill response planning and preparation are …

Addressing Health Disparities In Refugees, Claire E. Lopez

Master's Projects and Capstones

I completed the required 300 hours of my fieldwork internship at the International Rescue Committee (IRC) in Oakland, CA. The International Rescue Committee (IRC) is a non-profit international organization that responds to the world’s worst humanitarian crises and aids displaced individuals in rebuilding their lives in new countries by providing support in health care, finance, education, infrastructure, and resettlement.

I worked as a Health Access/Intensive Case management Intern. As a Health Access Program Intern, it was my job to ensure that refugees coming to the United States had a place to seek medical care, advice, and preventative services. In order …

Content-Based Instruction And Corpus Linguistics Curriculum For Early Advanced Efl Saudi Students, Ahmed Alattar

Master's Projects and Capstones

For many years now EFL teaching and learning in Saudi Arabia has suffered from a lack of authentic life-related and meaningful materials. Most of the EFL books available, therefore, pay more attention to form and less attention to meaning. This has resulted in many Saudi EFL students having difficulty improving their L2 proficiency. For this reason, I developed a curriculum that incorporates content-based instruction and corpus linguistics. The curriculum is divided into six units. The units focus on the five basic language skills: Reading, Writing, Listening, and Speaking. Each unit focuses on different content and includes examples form several corpus …

Dilema Antara Hobi Dan Bisnis Perdagangan Burung Serta Konservasi Burung, Johan Iskandar

Chimica et Natura Acta

Paper discusses result of study on the development of hobby on bird keeping, bird song contest, bird trade business, and conservation strategy for bird sustainable use, based on case study undertaken in the Bandung urban and surrounding areas. The combination of qualitative and quantitative method with descriptive analysis was used in this study. The result of study shows that based on direct inventory it was recorded 96 bird species of 24 families which were being kept by thirty respondents. Among the total species, 29 species and races were recorded as domit, namely anis merah (Zoothera citrina), murai batu (Copsychus malabaricus), …

“Une Image Vaut Bien Mille Mots”: Recherche Sur L’Iconographie Des Textes Allégoriques De Christine De Pizan, Marie-Josee Marquis

Doctoral Dissertations

The following research paper is an iconographic analysis of six allegoric works of Christine the Pizan, including: Epistre Othea, Livre de la Cité des Dames, Livre des Trois Vertus, Livre du Chemin de long estude, Livre de la mutacion de Fortune et Livre de l’advision Cristine. These medieval writings will be analyzed in conjunction with their illuminations allowing as such a more complete understanding of the various details buried within the images. Iconography, codicology and paleography are the three analytic methods utilized in this comprehensive study of selected Christine de Pizan’s allegoric works. Furthermore, this study will illustrate the …

The Future Of Direct Potable Reuse In California: Overcoming Public Acceptance Barriers, Allison Chan

Master's Projects and Capstones

Due to the water shortages, population growth, and competing demands for water in California, the possibility of incorporating direct potable reuse technology in the state’s water supply portfolio is being considered by various water resource providers. This paper focuses on public acceptance challenges that may be encountered. By evaluating best practices employed by six different potable water reuse case studies, recommendations for future direct potable reuse projects are developed. It is recommended that future project proponents plan early and conduct public opinion surveys regarding this type of technology, develop and implement public outreach and education plans that include best practices …

Remediation Options For Mercury-Contaminated Sediments Within The Yuba River Watershed, Tara Fitzgerald

Master's Projects and Capstones

Historical hydraulic mining activities in the Yuba River watershed have impacted the watershed and the San Francisco Bay. The research evaluates pathways for mercury entry into the watershed and potential remediation technologies to reduce the risk of future mercury contamination from hydraulic mining debris. Remediation technologies for the Yuba Goldfields and Englebright Reservoir are discussed and compared separately. The major pathway for mercury entry into surface water along Yuba Goldfields is within suspended sediment mobilized during flooding conditions. While multiple remediation options are available for the Yuba Goldfields, phytostabilization is the least costly and has the fewest environmental impacts. A …

The Role Of Chemokine Receptor Cxcr7 With Egfr In Breast Cancer Cell Proliferation, Nicole Salazar

Open Access Dissertations

Recent advances have revealed a significant contribution of chemokines and their receptors in tumor growth, survival after chemotherapy and organ-specific metastasis. The CXC chemokine receptor-7 (CXCR7) is the latest chemokine receptor implicated in cancer. Although over expressed in breast cancer cell lines and tumor tissues, its mechanism of action in breast cancer (BrCa) growth and metastasis was not clear. Studies in other cancers have implicated CXCR7 in cell proliferation, anti-apoptotic activity and cell-cell adhesion. The present study was initiated to examine the pattern of CXCR7 expression and its role in regulation of growth signaling in breast cancer. The contribution of …

The South Has Not Risen In Nhl Attendance Numbers Compared To The North, Kyle Stich

Sport Management Undergraduate

This research looked at attendance capacity for traditional and non-traditional hockey markets. The aim was to attempt to determine the extent the attendance capacities differed between the two markets. Previously, there had not been any quantitative analyses done comparing traditional and non-traditional hockey markets so this study aimed to add new knowledge to that area. The National Hockey League (NHL) grapples with the validity of some of the current markets, with many observers calling for some teams to relocate to new markets. This research aimed to attempt to determine how justified those criticisms were.

Kim, Trail, & Magnusen (2013) have …

P53 And Cancer-Associated Sialylated Glygans Are Surrogate Markers Of Cancerization Of The Bladder Associated With Schistosoma Haematobium Infection, Julio Santos, Elisabete Fernandes, Jose Alexandre Ferreira, Luis Lima, Ana Tavares, Andreia Peixoto, Beatriz Parreira, Jose Manuel Correia Da Costa, Paul J. Brindley, Carlos Lopes, Lucio L. Santos

Microbiology, Immunology, and Tropical Medicine Faculty Publications

Background

Bladder cancer is a significant health problem in rural areas of Africa and the Middle East where Schistosoma haematobium is prevalent, supporting an association between malignant transformation and infection by this blood fluke. Nevertheless, the molecular mechanisms linking these events are poorly understood. Bladder cancers in infected populations are generally diagnosed at a late stage since there is a lack of non-invasive diagnostic tools, hence enforcing the need for early carcinogenesis markers.

Methodology/Principal Findings

Forty-three formalin-fixed paraffin-embedded bladder biopsies of S. haematobium-infected patients, consisting of bladder tumours, tumour adjacent mucosa and pre-malignant/malignant urothelial lesions, were screened for bladder …

Expression Of Suppressor Of Cytokine Signaling 1 (Socs1) Impairs Viral Clearance And Exacerbates Lung Injury During Influenza Infection., Keer Sun, Sharon Salmon, Vijaya Kumar Yajjala, Christopher Bauer, Dennis W. Metzger

Journal Articles: Pathology and Microbiology

Suppressor of cytokine signaling (SOCS) proteins are inducible feedback inhibitors of cytokine signaling. SOCS1-/- mice die within three weeks postnatally due to IFN-γ-induced hyperinflammation. Since it is well established that IFN-γ is dispensable for protection against influenza infection, we generated SOCS1-/-IFN-γ-/- mice to determine whether SOCS1 regulates antiviral immunity in vivo. Here we show that SOCS1-/-IFN-γ-/- mice exhibited significantly enhanced resistance to influenza infection, as evidenced by improved viral clearance, attenuated acute lung damage, and consequently increased survival rates compared to either IFN-γ-/- or WT animals. Enhanced viral clearance in SOCS1-/-IFN-γ-/- mice coincided with a rapid onset of adaptive immune …

Spatial Variation In The Littoral Vertebrate Community Of A Reservoir Relative To Physical And Biological Gradients, Nathan Ruhl, Jessica J. Soski, Willem M. Roosenburg

College of Science & Mathematics Departmental Research

Reservoirs possess gradients in conditions and resources along their long (deep-shallow) axis, but the response of littoral vertebrates (fish and turtles) to these gradients is poorly understood. We have quantified the littoral vertebrate communities throughout a small reservoir in Southeastern Ohio during July and August using traps, and related community composition to environmental variables using NMDS ordination. Ordination revealed that fish and turtles were broadly separated in ordination space, and three distinctly different environmental gradients were significantly associated with the underlying observed species abundances. Observed turtle abundance was explained by measurements of bathymetry, turbidity, and benthic resources, but none of …

Ifn-Γ Causes Aplastic Anemia By Altering Hematopoietic Stem/Progenitor Cell Composition And Disrupting Lineage Differentiation, Fan Ching Lin, Megan Karwan, Bahara Saleh, Deborah L. Hodge, Tim Chan, Kimberly C. Boelte, Jonathan R. Keller, Howard A. Young

United States Public Health Resources

Aplastic anemia (AA) is characterized by hypocellular marrow and peripheral pancytopenia. Because interferon gamma (IFN-γ) can be detected in peripheral blood mononuclear cells of AA patients, it has been hypothesized that autoreactive T lymphocytes may be involved in destroying the hematopoietic stem cells. We have observed AA-like symptoms in our IFN-γ adenylate-uridylate-rich element (ARE)-deleted (del) mice, which constitutively express a low level of IFN-γ under normal physiologic conditions. Because no T-cell autoimmunity was observed, we hypothesized that IFN-γ may be directly involved in the pathophysiology of AA. In these mice, we did not detect infiltration of T cells in bone …

Comparative Genome Analyses Reveal Distinct Structure In The Saltwater Crocodile Mhc., Weerachai Jaratlerdsiri, Janine Deakin, Ricardo M. Godinez, Xueyan Shan, Daniel G. Peterson, Sylvain Marthey, Eric Lyons, Fiona M. Mccarthy, Sally R. Isberg, Damien P. Higgins, Amanda Y. Chong, John St. John, Travis C. Glenn, David A. Ray, Jaime Gongora

CALS Publications

The major histocompatibility complex (MHC) is a dynamic genome region with an essential role in the adaptive immunity of vertebrates, especially antigen presentation. The MHC is generally divided into subregions (classes I, II and III) containing genes of similar function across species, but with different gene number and organisation. Crocodylia (crocodilians) are widely distributed and represent an evolutionary distinct group among higher vertebrates, but the genomic organisation of MHC within this lineage has been largely unexplored. Here, we studied the MHC region of the saltwater crocodile (Crocodylus porosus) and compared it with that of other taxa. We characterised genomic clusters …

Transceptors At The Boundary Of Nutrient Transporters And Receptors: A New Role For Arabidopsis Sultr1;2 In Sulfur Sensing, Zheng Zhiliang, Bo Zheng, Thomsa Leustek

Publications and Research

Plants have evolved a sophisticated mechanism to sense the extracellular sulfur (S) status so that sulfate transport and S assimilation/metabolism can be coordinated. Genetic, biochemical, and molecular studies in Arabidopsis over the past 10 years have started to shed some light on the regulatory mechanism of the S response. Key advances in transcriptional regulation (SLIM1, MYB, and miR395), involvement of hormones (auxin, cytokinin, and abscisic acid) and identification of putative sensors (OASTL and SULTR1;2) are highlighted here. Although our current view of S nutrient sensing and signaling remains fragmented, it is anticipated that through further studies a sensing and signaling …