Digital Commons Network^™

Development Of A Static Bioactive Stent Prototype And Dynamic Aneurysm-On-A-Chip(Tm) Model For The Treatment Of Aneurysms, Lisa M. Reece

Open Access Dissertations

Aneurysms are pockets of blood that collect outside blood vessel walls forming dilatations and leaving arterial walls very prone to rupture. Current treatments include: (1) clipping, and (2) coil embolization, including stent-assisted coiling. While these procedures can be effective, it would be advantageous to design a biologically active stent, modified with magnetic stent coatings, allowing cells to be manipulated to heal the arterial lining. Further, velocity, pressure, and wall shear stresses aid in the disease development of aneurysmal growth, but the shear force mechanisms effecting wound closure is elusive. Due to these factors, there is a definite need to cultivate …

Migratory Ecology Of Sea Turtles, Nathan Jack Robinson

Open Access Dissertations

Establishing the movement patterns of free-ranging animals is imperative to understanding their behavior and ecology, and is often necessary for designing effective conservation-strategies. This is especially true for migratory species, such as sea turtles, whose long-distance movements form a major component of their life history. In this thesis, I investigated which factors are driving the migratory behavior of the leatherback turtleDermochelys coriacea. Firstly, I examined whether the timing of the nesting season (nesting phenology) is influenced by oceanographic conditions along the pre-nesting migratory route or by variation in population structure. The discovery that nesting phenology appears more influenced by …

Soil Quality And Nitrogen Cycling Dynamics Altered By Fertility Amendments In Intensively Managed Vegetable Production Systems, Matt A. Rudisill

Open Access Dissertations

Fresh market vegetable production in the Midwest U.S. is growing rapidly as a result of increased demand for locally-sourced food. High tunnels are becoming increasingly popular among Midwest vegetable growers as these structures offer many production benefits including season extension. However, vegetables require substantial fertility inputs, particularly nitrogen (N), in order to meet desired levels of productivity, and some fertility management strategies can negatively impact soil and environmental quality. This can be particularly problematic in high tunnels, where longer production periods and modification of the growing environment put these systems at greater risk for soil degradation. Identification of fertility practices …

A New Passive Surface Water Flux Meter For Simultaneous Measurement Of Contaminant And Water Fluxes In Streams And Rivers, Stephen A. Sassman

Open Access Dissertations

A passive surface water flux meter (PSFM) for measurement of contaminant concentration/flux in rivers and streams is described and tested. The novel PSFM design was developed for portability and ease of adaptability for a variety of contaminant classes. Although previous designs have been evaluated under constant flow conditions, the PSFM has never been used for measurement of pesticides or hormones and this is the first time that it has been tested under transient flow. Discharge through the PSFM is assessed by measuring miscible displacement of alcohol tracers from granular activated carbon (GAC). The tracer retardation factors (R) measured by miscible …

Understanding Preferred Leg Stiffness And Layered Control Strategies For Locomotion, Zhuohua H. Shen

Open Access Dissertations

Despite advancement in the field of robotics, current legged robots still cannot achieve the kind of locomotion stability animals and humans have. In order to develop legged robots with greater stability, we need to better understand general locomotion dynamics and control principles. Here we demonstrate that a mathematical modeling approach could greatly enable the discovery and understanding of general locomotion principles. ^ It is found that animal leg stiffness when scaled by its weight and leg length falls in a narrow region between 7 and 27. Rarely in biology does such a universal preference exist. It is not known completely …

Combining And Mapping Qtl For Fusarium Head Blight (Fhb) Resistance In Wheat, Jin Sun

Open Access Dissertations

Fusarium head blight (FHB) has become one of the most damaging wheat diseases in humid and semi-humid regions around the world. Single gene resistance to FHB in wheat provides only partial resistance and also the disease severity is highly influenced by environment. Consequently multiple genes are required for effective resistance. Our hypothesis is that identifying DNA markers for type I resistance will be very beneficial for selection, and combining type I and type II FHB resistance will be more effective than either type alone. The objectives of this project are to 1) combine type I resistance from cultivars Goldfield, INW0412, …

Morphometric Characterization Of Individual Sympathetic Postganglionic Axons Innervating The Muscle Layers Of The Gastrointestinal Tract Of The Rat: A Complex Effector Model, Gary C. Walter

Open Access Dissertations

A full description of the terminal morphology of sympathetic postganglionic axons innervating the musculature of the gastrointestinal (GI) tract has not been available. Furthermore, common assumptions about the morphology and distribution of catecholaminergic terminal fields have been strongly shaped by the limitations of the techniques employed to distinguish the fibers and complicated by inconsistent findings generated with various methodologies. Thus, the present experiment used modern neural tracer techniques to provide high-resolution labeling of sympathetic fibers projecting to the smooth muscle wall of the GI tract. Fischer 344 rats (N = 50) received injections of dextran biotin into the left …

Role Of Group Ii Metabotropic Glutamate Receptor Subtype 2 (Mglur2) In Appetitive And Consummatory Aspects Of Ethanol Reinforcement, Kyle Allyson Windisch

Open Access Dissertations

Background: Group II metabotropic glutamate receptors (mGluR2/3) are predominately presynaptically located G_i/o coupled receptors that are highly expressed in the cortex, nucleus accumbens, amygdala, and hippocampus. Previous studies suggest that group II mGluRs are involved in regulating ethanol (EtOH) consumption and seeking following extinction (Backstrom and Hyytia, 2005; Kufahl, et al., 2011). The sipper tube model, which allows for procedural separation of seeking and consumption, was used to further clarify the role of mGluR2/3 in EtOH-seeking and consumption. The non-selective group II mGluR agonist LY379268 (LY37) and selective mGluR2 positive allosteric modulator (PAM) BINA were used to determine the …

Current Steering And Electrode Spanning With Partial Tripolar Stimulation Mode In Cochlear Implants, Ching-Chih Wu

Open Access Dissertations

Cochlear implants (CIs) partially restore hearing sensation to profoundly deaf people by electrically stimulating the surviving auditory neurons. However, CI users perform poorly in challenging listening tasks such as speech recognition in noise and Cochlear implants (CIs) partially restore hearing sensation to profoundly deaf people by electrically stimulating the surviving auditory neurons. However, CI users perform poorly in challenging listening tasks such as speech recognition in noise and music perception, possibly due to the small number of implanted electrodes and the large current spread of electric stimulation. Although current spread may be reduced using partial tripolar (pTP) stimulation mode, the …

Nano-Engineered Polymers In Drug Delivery: Potential Approaches For Attenuation Of Secondary Injury After Spinal Cord Trauma, Wen Gao

Open Access Dissertations

Secondary injury elicits a complex series of pathophysiological events after the primary spinal cord trauma and even after its implantation treatment for neural functional recovery. These secondary injuries include an up-regulation of glial cells associated reactive oxygen species, nitrogen species, and reactive astrogliosis, and they can result in various levels of cellular and tissue damage. The inhibition of them has been proved to lead to functional recovery of the spinal cord. In this study, we concentrated on developing polymers and nano-techniques based drug delivery strategies to eliminate these secondary injuries. ^ To maintain and improve the performance of the implants …

The Effects Of A Humorous Instructional Video On Motivation And Learning, Hans P. Aagard

Open Access Dissertations

This study examines the effects of humor within an instructional video on student learning and motivation. Humor in education has been shown to improve students' perception of the instructor and learning environment, with mixed results on gains in actual learning. Humor has been suggested as a strategy to gain and maintain attention, improving motivation to learn. With the dramatic increase of online multimedia instruction, research on the use of humor on multimedia instructional materials can help us determine if it can be used to improve learning and motivation.

In a pretest-posttest controlled design, students viewed a short multimedia instructional video. …

Exploring Literacy And Technology With Middle School English Teachers: Articulating Understandings Of Knowledge And Teaching Practices, Benjamin A. Boche

Open Access Dissertations

The purpose of this study was to investigate five middle school English teachers' understandings of literacy and technology. In particular, how do they define literacy, view literacy and technology learning and teaching, and how do they use (or not use) technology to enact their views of literacy in their classrooms. This narrative inquiry qualitative study consisted of three open-ended interviews, written literacy narratives, and multiple classroom observations with each participant as well as the collection of various teacher documents, such as lesson plans, presentation notes, rubrics, and student handouts. Narrative methods were used in the data analysis. ^ Findings were …

Coordination Between Hand And Trunk Movements In A Fitts' Law Task, Fuwen Cai

Open Access Dissertations

It has been shown that limb movements are coupled in space and time in a bimanual Fitts' task. The present study was designed to examine whether coordination of hand and trunk share some sets of coordinative principles with bimanual coordination. Participants (n = 28) were required to perform a Fitts' task with the dominant hand and a Fitts' task with the trunk. These tasks were performed separately or together. The task required moving the trunk, the dominant hand or both, such that the cursor/cursors on a computer screen was/were moved from the starting position/positions to the designated target/targets as fast …

Associated Behavioral, Genetic, And Gene Expression Variation With Alternative Life History Tactics In Salmonid Fishes, Ashley Chin-Baarstad

Open Access Dissertations

Individual differences in behavior can have potential fitness consequences and often reflect underlying genetic variation. My research focuses on three objectives related to individual level variation: 1) evaluating the innate behavioral variation within and between individuals, families, and progeny of different life-history types across time; 2) testing for differences in gene expression within the brain associated with this behavioral variation; and 3) using genetic polymorphisms to test for associations with ecotype, as well as population structure, in polymorphic populations. First, we evaluated the variation in a suite of ecologically relevant behaviors across time in juvenile progeny produced from crosses within …

Irrigation With Treated Wastewater: Potential And Limitations, Anne Dare

Open Access Dissertations

As the world population increases and resources become more coveted, water emerges as a key component to global food security. The Middle East and North Africa (MENA) is among the driest regions in the world: containing just one percent of the world's freshwater resources. An increasing population creates greater quantities of wastewater and demands greater quantities of food, so an obvious connection arises. However logical wastewater reuse may be for bridging the irrigation supply-demand gap in this arid region, significant limitations prevent widespread adoption. The overall goal of this research is to take a holistic view of the limitations facing …

Constitutional Law—Shooting Blanks: Smart Gun Mandates And Their Concomitant Constitutional, Regulatory, Public Policy, And Practical Issues, William F. Godbold Iv

University of Arkansas at Little Rock Law Review

No abstract provided.

Advocacy From The Human Perspective: Advice For Young Appellate Lawyers, Douglas S. Levine

The Journal of Appellate Practice and Process

No abstract provided.

The Emergence Of Constitutionalism As An Evolutionary Adaptation, Fábio Portela L. Almeida

Cardozo Public Law, Policy & Ethics Journal

The emergence of modern societies is an evolutionary puzzle. Homo sapiens is the only animal species capable of cooperating in large-scale societies consisting of genetically unrelated individuals. From a biological point of view, this feature leads to enormous questions. Social scientists typically assume that human life is lived in large-scale societies as a result of cultural, social and institutional history. In this perspective, social institutions such as law, economy and religion enhance cooperation to higher levels. Gene-culture coevolutionary theories have studied this issue in an integrated framework that accounts for social and biological theories of cooperation. These theoretical approaches have …

Measurement Of Field Complex Noise Using A Novel Acoustic Detection System, Jun Qin, Pengfei Sun, Jacob Walker

Conference Proceedings

This paper represents our recent experimental measurement study of the complex noise in industrial fields, using a novel acoustic detection system and wavelet transform algorithms. Noise induced hearing loss (NIHL) continues to be one of the most prevalent occupational hazards in the United States. Number of research on NIHL showed a complex noise could produce more hearing loss than an energy-equivalent continuous or impulsive noise alone. Many workplaces in varied industries are subjected to the high level complex noise (i.e., high-level impulsive noise mixed with continuous Gaussian noise). The current noise measurement guidelines and devices (e.g., conventional sound level meters) …

Affirmative Action: Between The Oikos And Cosmos Review Essay: Richard Sander & Stuart Taylor, Jr., Mismatch: How Affirmative Action Hurts Students It's Intended To Help And Why Universities Won't Admit It, Harry G. Hutchinson

South Carolina Law Review

No abstract provided.

Nurse Practitioner Screening Practices For Mild Cognitive Impairment In The Older Adult, Margaret Mcilwain

Doctor of Nursing Practice (DNP) Translational and Clinical Research Projects

Abstract

Nurse practitioners (NPs/APRNs) who provide primary care services may be the first line providers in situations where adults present with symptoms of memory loss and forgetfulness. Though protocols are available for evaluating dementia, specific guidelines for evaluating early cognitive changes, Mild Cognitive Impairment (MCI), are lacking. This descriptive research project assesses the knowledge, current screening methods, and barriers to screening for MCI by nurse practitioners (APRNs) in the state of Georgia. One hundred and thirty two NPs participated in the survey. Forty-five percent of the participants were unfamiliar with the diagnostic category of MCI. Of the major barriers identified, …

Caroliniana Columns - Fall 2014, University Libraries--University Of South Carolina

University South Caroliniana Society Newsletter - Columns

Contents:

Lanny and Sidney Palmer Establish Endowment Fund and Cultural Arts Collection at the South Caroliniana Library..... p.1
John Hammond Moore Honored on His Ninetieth Birthday..... p.1
Letter from the Dean of Libraries..... p.4
The Schuyler & Yvonne Moore Alcove..... p.4
"Remembering the Days...": Havilah Babcock..... p.6
“Slaves of the Rebel Gen. T.F. Drayton, Hilton Head Island, S.C.”..... p.7
New Faces..... p.7
Reports from 2014 Summer Scholars..... p.8
Each Picture Is Worth a Thousand Words: The South Caroliniana Library Portrait Collection..... p.10
Celebrating South Carolina’s Literary Heritage: Archibald Rutledge and Julia Peterkin..... p.11
Stephen Chesley Talks about Illustrating …

Molecular Variation In Avp And Avpr1a In New World Monkeys (Primates, Platyrrhini): Evolution And Implications For Social Monogamy, Dongren Ren, Kelvin R. Chin, Jeffrey French

Biology Faculty Publications

The neurohypophysial hormone arginine vasopressin (AVP) plays important roles in fluid regulation and vascular resistance. Differences in AVP receptor expression, particularly mediated through variation in the noncoding promoter region of the primary receptor for AVP (AVPR1a), may play a role in social phenotypes, particularly social monogamy, in rodents and humans. Among primates, social monogamy is rare, but is common among New World monkeys (NWM). AVP is a nonapeptide and generally conserved among eutherian mammals, although a recent paper demonstrated that some NWM species possess a novel form of the related neuropeptide hormone, oxytocin. We therefore characterized variation in the AVP …

Hypogammaglobulinemia In Blt Humanized Mice – An Animal Model Of Primary Antibody Deficiency, Francisco Martinez-Torres, Tomonori Nochi, Angela Wahl, J. Victor Garcia, Paul W. Denton

Biology Faculty Publications

Primary antibody deficiencies present clinically as reduced or absent plasma antibodies without another identified disorder that could explain the low immunoglobulin levels. Bone marrow-liver-thymus (BLT) humanized mice also exhibit primary antibody deficiency or hypogammaglobulinemia. Comprehensive characterization of B cell development and differentiation in BLT mice revealed other key parallels with primary immunodeficiency patients. We found that B cell ontogeny was normal in the bone marrow of BLT mice but observed an absence of switched memory B cells in the periphery. PC-KLH immunizations led to the presence of switched memory B cells in immunized BLT mice although plasma cells producing PCor …

Detection Of Bacterial Antigens And Alzheimer's Disease-Like Pathology In The Central Nervous System Of Balb/C Mice Following Intranasal Infection With A Laboratory Isolate Of Chlamydia Pneumoniae, C. Scott Little Phd, Timothy A. Joyce, Christine Hammond, Hazem Matta, David Cahn, Denah Appelt, Brian J. Balin Phd

PCOM Scholarly Works

Pathology consistent with that observed in Alzheimer’s disease (AD) has previously been documented following intranasal infection of normal wild-type mice with Chlamydia pneumoniae (Cpn) isolated from an AD brain (96-41). In the current study, BALB/c mice were intranasally infected with a laboratory strain of Cpn, AR-39, and brain and olfactory bulbs were obtained at 1-4 months post-infection (pi). Immunohistochemistry for amyloid beta or Cpn antigens was performed on sections from brains of infected or mock-infected mice. Chlamydia-specific immunolabeling was identified in olfactory bulb tissues and in cerebrum of AR-39 infected mice. The Cpn specific labeling was most prominent at 1 …

Speech Beyond Borders: Extraterritoriality And The First Amendment, Anna Su

Vanderbilt Law Review

Does the First Amendment follow the flag? In Boumediene v. Bush, the Supreme Court categorically rejected the claim that constitutional rights do not apply at all to governmental actions taken against aliens located abroad. Instead, the Court made the application of such rights, the First Amendment presumably included, contingent on "objective factors and practical concerns." In addition, by affirming previous decisions, Boumediene also extended its functional test to cover even U.S. citizens, leaving them in a situation where they might be without any constitutional recourse for violations of their First Amendment rights. But lower courts have found in the recent …

Security Policies That Make Sense For Complex Systems: Comprehensible Formalism For The System Consumer, Rhonda R. Henning

CCAC Theses and Dissertations

Information Systems today rarely are contained within a single user workstation, server, or networked environment. Data can be transparently accessed from any location, and maintained across various network infrastructures. Cloud computing paradigms commoditize the hardware and software environments and allow an enterprise to lease computing resources by the hour, minute, or number of instances required to complete a processing task. An access control policy mediates access requests between authorized users of an information system and the system's resources. Access control policies are defined at any given level of abstraction, such as the file, directory, system, or network, and can be …

Satellite Remote Sensing And Database Management: Who Owns The Digitized Information Relating To Indigenous People And Their Artifacts, Brenda Reddix-Smalls

North Carolina Central Law Review

No abstract provided.

Fiction Fix 16, April Gray Wilder, Jayshiro Tashiro, Christopher Stephen, Cathleen Calbert, Amanda Paulger, Van G. Garrett, Jane Zich, Di Jayawickrema, Josh Lamstein, Liz Dolan, Denise Mostacci Sklar, Holly Day, Erica W. Jamieson, Jack King, Meeah Williams, Glenn Erick Miller, Edward Hagelstein

Fiction Fix

No abstract provided.

October In Galicia, Karen J. Siegel

Dissertations, Theses, and Capstone Projects

October in Galicia is a setting of selections from the Czech poet Ewald Murrer’s fantastical book, The Diary of Mr. Pinke, translated into English by Alicie Pi!t’ková. The surreal day-to-day happenings of Mr. Pinke occur in a timeless group of villages revealed by a translator’s note to be modeled on the historical region of Galicia (now part of Poland, Ukraine, and Russia). The tape part (or more accurately the digital audio files), which appears in “October 23rd,” consists of an organ recording that has been manipulated electronically. The electronic manipulations are subtle enough that the original pitches are always …