Digital Commons Network^™

Contents, Discovery Editors

Discovery, The Student Journal of Dale Bumpers College of Agricultural, Food and Life Sciences

No abstract provided.

Access And Benefit Sharing Of Marine Genetic Resources From Areas Beyond National Jurisdiction: Intellectual Property--Friend, Not Foe, Eve Heafey

Chicago Journal of International Law

The applicable international legal framework for the governance of marine genetic resources from areas beyond national jurisdiction is difficult to sort out- at best, it is unclear under which regime such resources fall, and at worst, there is no applicable regime. Despite the ambiguity, the bioprospecting of these resources is ongoing and increasingly being undertaken for commercial purposes. It follows that intellectual property claims, such as patents on inventions and copyrights on publications describing discoveries, are being sought in relation to inventions and publications deriving from these bioprospecting efforts. As a result, nation states are raising important questions regarding the …

Renewable Energy Subsidies And The Gatt, Virginia R. Hildreth

Chicago Journal of International Law

Renewable energy is an increasingly important topic in today's global world and marketplace. This Comment analyzes the current World Trade Organization plan for addressing renewable energy and proposes an alternate solution to that plan modeled on the Agreement on Agriculture. This Comment notes how, with the present lack of a specific WITO agreement on renewable energy, these subsidies must be treated like all other industrial subsidies, despite their environmental benefits. Current WUTO exceptions for environmentally beneficial programs require relatively pure environmental motives in order to be exempt, and thus do not embrace subsidies with a developmental focus. This Comment specifically …

Green Mimesis: Girard, Nature, And The Promise Of Christian Animism, Mark I. Wallace

Religion Faculty Works

No abstract provided.

Kingswood Lake Management Plan, Sarah Martina Tierney

Honors Theses and Capstones

High water quality and natural buffers exist on Kingswood Lake located in Brookfield, New Hampshire. A comprehensive lakes inventory (CSI) was recorded and health of the land, wildlife, and waterways were observed. Educational outreach was taken to inform the local community and to instruct them on proper stewardship of the land. A completed watershed management plan was constructed including key recommendation of limiting nitrogen loading in the area, checking septic systems for leaching, stabilizing shoreline from erosion, and establishing man-made rain gardens to help preserve water quality. The Kingswood watershed management plan acts as a guide for the town of …

Savings Account For Microenterprise, Meghan Jarow

Honors College Theses

Will bundling savings accounts with loans increase the effectiveness of microfinance as a tool for alleviating poverty? Microfinance is the practice of offering small loans to poor people in developing countries. The development of this practice into a poverty dimishining, self-sustaining business won Muhammad Yunus a Nobel Prize in 2006. Today, there are thousands of microfinance institutions (MFIs) serving millions of people in developing countries. However, there is recent evidence that these loans do not help reduce poverty, and may do as much ahrm as good.

In truth providing credit to the poor may not be enough to eliminate poverty. …

Introduction: Questioning, Challenging And Advocating: Advancing Knowledge In Composition And Rhetoric, Julia Voss, Beverly J. Moss

English

No abstract provided.

Is Batman A State Actor? The Dark Knight's Relationship With The Gotham City Police Department And The Fourth Amendment Implications, Joshuah Lisk

Case Western Reserve Law Review

No abstract provided.

A Unifying Model For Neoproterozoic-Palaeozoic Exceptional Fossil Preservation Through Pyritization And Carbonaceous Compression, James D. Schiffbauer, Shuhai Xiao, Yaoping Cai, Adam F. Wallace, Hong Hua, Jerry Hunter, Huifang Xu, Yongbo Peng, Alan J. Kaufman

Faculty Publications

© 2014 Macmillan Publishers Limited. All rights reserved. Soft-tissue fossils capture exquisite biological detail and provide our clearest views onto the rise of animals across the Ediacaran-Cambrian transition. The processes contributing to fossilization of soft tissues, however, have long been a subject of debate. The Ediacaran Gaojiashan biota displays soft-tissue preservational styles ranging from pervasive pyritization to carbonaceous compression, and thus provides an excellent opportunity to dissect the relationships between these taphonomic pathways. Here geochemical analyses of the Gaojiashan fossil Conotubus hemiannulatus show that pyrite precipitation was fuelled by the degradation of labile tissues through bacterial sulfate reduction (BSR). Pyritization …

The Kabbalah Of Forgiveness, Henry M. Abramson

Lander College of Arts and Sciences Books

The Kabbalah of Forgiveness is a translation of the first chapter of Rabbi Moshe Cordovero’s classic work Date Palm of Devorah (Tomer Devorah) with a commentary by Dr. Henry Abramson. Emerging from the 16th-century Safed Circle of Jewish mystics, this book earned a rare exception to the centuries-old ban on the study of Kabbalah by students under 40 because of its profound ethical value.

Experiential Education As Critical Pedagogy, Spearit, Stephanie Smith Ledesma

Nova Law Review

No abstract provided.

Yale Medicine : Alumni Bulletin Of The School Of Medicine, Winter 2014, Yale University. School Of Medicine

Yale Medicine Magazine - alumni bulletin and magazine

This is the Winter 2014 issue of Yale Medicine: alumni bulletin of the School of Medicine, v. 48, no. 1. Prepared in cooperation with the alumni and development offices at the School of Medicine. Earlier volumes are called Yale School of Medicine alumni bulletins, dating from v.1 (1953) through v.13 (1965).

Antidepressants And Melanoma: Is There A Link?, Stephanie Douglas

Yale Medicine Thesis Digital Library

ANTIDEPRESSANTS AND MELANOMA: IS THERE A LINK? Stephanie R. Douglas, Deepak Narayan. Section of Plastic and Reconstructive Surgery, Department of Surgery, Yale University School of Medicine, New Haven, CT.

Cutaneous melanoma is the sixth most common cancer in the United States, and its incidence continues to rise steadily at a rate of 2-3% per year. Meanwhile nearly 11% of the general population is treated with antidepressant medication. Laboratory studies suggest a number of theoretical links between antidepressants and melanoma. Serotonin is a growth factor for melanocytes, and antidepressants upregulate components of the Wnt/beta-catenin, mTOR, and MAP kinase signaling pathways, all …

Eph-B4 Activation Reduces Neointimal Hyperplasia In Human Saphenous Vein, Daniel James Wong

Yale Medicine Thesis Digital Library

Despite the rise in percutaneous interventions, bypass surgery is an essential therapy for patients with advanced coronary and peripheral artery disease. Nearly half of the saphenous vein grafts used in these operations are eventually complicated by pathologic remodeling known as neointimal hyperplasia (NIH). Recent work in animal models has shown that the development of NIH can be reduced by stimulation of the receptor tryrosine kinase Eph-B4 by systemic injections of its ligand ephrin-b2. The purpose of this study was to determine whether the reduction of intimal hyperplasia observed with Eph-B4 stimulation in animal models translated into human tissues. Specifically we …

The Postcolonial Problem For Global Gay Rights, Stewart Chang

Scholarly Works

As the United States and Europe have progressed to the issue of same-sex marriage, countries that are still working through antecedent issues, such as the decriminalization of anti-sodomy laws, are regarded by international gay rights advocates as lagging behind the times. This often leads to pressures from the Western-dominated international community for reform. Through this Article, Professor Stewart Chang contributes to the ongoing scholarly debate between international human rights activists who desire to advance gay rights by utilizing the same rights-based models that prevail in the United States and Europe and critics of this approach who deem the universal imposition …

Conferring About The Conference (Recalibrating Copyright: Continuity, Contemporary Culture, And Change), Marketa Trimble

Scholarly Works

Professor Marketa Trimble and her colleagues Professors Jessica Silbey and Aaron Perzanowski reflect on papers presented at the University of Houston Law Center's Institute for Intellectual Property & Information Law's annual conference held in Spring of 2014.

Religion And The Restatements, Ian C. Bartrum

Scholarly Works

This essay is a contribution to the symposium entitled "Restatement of ..." held at Brooklyn Law School in January of 2013. It examines the role that conceptions of religious liberty play in the various Restatements, and suggests a few places where the ALI might consider expanding its discussion of these principles.

The Sincerest Form Of Flattery: Examples And Model-Based Learning In The Law School Classroom, Terrill Pollman

Scholarly Works

Responding to a changing landscape of law practice, law schools are searching for ways to structure the classroom experience and broader curriculum to promote more efficient and better learning outcomes. Although imitation, modeling, and the use of examples have become pre-eminent features of modern legal education, these pedagogies have remained largely unexamined. This article shows the power of teaching with examples in both the traditional and legal writing classroom, as well as how skillfully to limit the use of such pedagogy for maximum effect. Specifically, this article applies the findings of cognitive load research and composition theory to show that …

Improving Human Health By Increasing Access To Natural Areas: Opportunities And Risks, Bradford S. Gentry, David Krause, Karen A. Tuddenham, Sarah Barbo, Benjamin D. Rothfuss, Christopher Rooks

Yale School of the Environment Publications Series

Report of the 2013 Berkley Workshop

Held at the Pocantico Center of the Rockefeller Brothers Fund, Tarrytown, NY - July 2013

The Trouble With Categories: What Theory Can Teach Us About The Doctrine-Skills Divide, Linda H. Edwards

Scholarly Works

We might not need another article decrying the doctrine/skills dichotomy. That conversation seems increasingly old and tired. But like it or not, in conversations about the urgent need to reform legal education, the dichotomy’s entailments confront us at every turn. Is there something more to be said? Perhaps surprisingly, yes. We teach our students to examine language carefully, to question received categories, and to understand legal questions in light of their history and theory. Yet when we talk about the doctrine/skills divide, we seem to forget our own instruction.

This article does not exactly take sides in the typical skills …

Medicine@Yale July/August 2014 Volume 10, Issue 2, Yale School Of Medicine Office Of Communications

Medicine@Yale - development newsletter

Medicine@Yale : advancing biomedical science, education and health care was a print and online newsletter which published news about academics, research and philanthropy for alumni, donors, faculty, students and the general public. It was initially published 6 times a year and then changed to a quarterly schedule. The first issue came out June/Jul. 2005. The final issue was published in May/June 2022, vol. 17, issue 1. Published by Yale School of Medicine, Office of Communications.

Decadent Wealth, Degenerate Morality, Dominance, And Devotion: The Discordant Iconicity Of The Rich Mountain Of Potosí, Claudia A. Cornejo Happel

Publications

The rich mountain of Potosí, with its famed silver mines, has commanded the attention of Europeans, creoles (Americans of Spanish descent), and indigenous Andeans since the Spanish colonizers of Peru were made aware of its existence in 1545. Soon after its discovery, the rich mountain was represented in a variety of written and visual texts created by writers and artists from the Andes, Spain, and other parts of Europe. Independent of its physical form, in these representations the rich mountain assumed a discursive meaning, functioning as an icon that, depending on the context, represented abstract ideas of wealth, immorality, dominance, …

Warmer Temperatures Increase Disease Transmission And Outbreak Intensity In A Host-Pathogen System, Bret D. Elderd, James R. Reilly

Faculty Publications

Summary: While rising global temperatures are increasingly affecting both species and their biotic interactions, the debate about whether global warming will increase or decrease disease transmission between individuals remains far from resolved. This may stem from the lack of empirical data. Using a tractable and easily manipulated insect host-pathogen system, we conducted a series of field and laboratory experiments to examine how increased temperatures affect disease transmission using the crop-defoliating pest, the fall armyworm (Spodoptera frugiperda) and its species-specific baculovirus, which causes a fatal infection. To examine the effects of temperature on disease transmission in the field, we manipulated baculovirus …

Chemopreventive Effects Of Pterostilbene In Metastatic Prostate Cancer Cells, Phillip A. Zook

PCOM Biomedical Studies Student Scholarship

Recent studies find that pterostilbene (PTS) exhibits more favorable drug properties and similar chemopreventive effects to its structural analogue resveratrol (RSV). However, few studies describe the activity of PTS in prostate cancer (PCa). Here, we conducted cell count experiments to assess the effects of PTS on metastatic PCa cell viability and to compare the potency of PTS to RSV in this respect. We also performed experiments to assess the effects of PTS on the androgen receptor (AR) and AR-mediated events. We used qPCR to measure the mRNA levels of the androgenresponsive gene (ARG), prostate-specific antigen (PSA), and Western blots to …

An Analysis Of Abnormal Electrocardiograms In First And Second Year Medical School Students, Molly Anne Kalish

PCOM Biomedical Studies Student Scholarship

The high stress level placed upon medical school students, particularly during their first and second didactic years, may have a negative effect on their health. Although surveys and subjective questionnaires have been used to evaluate the effects medical school has upon a student’s cardiovascular health, there has been little clinical data obtained to confirm this notion. The aim of this longitudinal study was to demonstrate whether any abnormal cardiovascular parameters, specifically QTc wave interval, cardiac axis vector and blood pressure abnormalities, could be documented to occur in two different classes of medical students during their first two years. Such information …

Effect Of Heme Oxygenase-1 On Matrix Metalloproteinase-3 Expression In Human Fibroblasts, Theresa A. Stangl

PCOM Biomedical Studies Student Scholarship

Heme oxygenase-1(HO-1) is an enzyme that plays a very important role in the resolution of inflammation. HO-1-based therapies are effective in a number of disease conditions. However, HO-1 also increases tumor growth, angiogenesis, metastasis and chemoresistance. Matrix metalloproteinase-3 (MMP-3) is an enzyme involved in physiological and pathophysiological tissue remodeling. Unbalanced expression of MMPs is a key feature of connective tissue destruction in chronic inflammatory conditions. Previously shown in this laboratory, the HO-1 inducer, hemin, increased MMP-3 mRNA expression in some HGF cultures. To assess whether HO-1 and/or its products regulate expression of MMP-3 in human fibroblasts, the effect of HO-1 …

The Effects Of Dihydrobiopterin And Tetrahydrobiopterin On Hydrogen Peroxide And Nitric Oxide Release During Extracorporeal Shockwave Lithotripsy (Eswl), Brittany Deiling

PCOM Biomedical Studies Student Scholarship

ESWL is an effective, non-invasive therapy utilized to fragment stones in the kidney and subsequently be cleared in the urinary tract. Although lithotripsy provides a safer alternative to invasive treatments for removing stones, ESWL may cause vasoconstriction after ESWL treatment, reducing renal blood flow, which can cause kidney damage leading to acute to chronic hypertension clinically. This may be due to kidney vascular endothelial dysfunction, which is characterized as increased oxidative stress and decreased endothelial nitric oxide synthase (eNOS)-derived nitric oxide (NO) bioavailability. We hypothesized that ESWL would decrease NO and increase hydrogen peroxide (H₂O₂) in …

Effect Of Tumor Necrosis Factorα On Expression Of Heme-Oxgenase1 In Human Gingival Fibroblasts, Jay Patel

PCOM Biomedical Studies Student Scholarship

Periodontitis is a chronic inflammatory disease that is characterized by activation of gingival fibroblasts to produce matrix metalloproteinases and other inflammatory mediators that contribute to destruction of tissues surrounding the teeth. In the United States, 22% of adults have a mild form of periodontal disease and 13% suffer from a severe form of the disease. In addition to tooth loss, periodontitis is associated with increased risk of several conditions, including diabetes, osteoporosis, rheumatoid arthritis and cardiovascular disease. Heme oxygenase-1 (HO-1) is activated by a wide variety of stressful stimuli and levels are increased in inflamed tissues. HO-1 degrades free heme, …

Regulating Domestic Intelligence Collection, Emily Berman

Washington and Lee Law Review

Scholars have long recognized that a Federal Bureau of Investigation wielding robust domestic intelligence-collection powers poses a threat to civil liberties. Yet the FBI’s post-9/11 mandate to prevent terrorist attacks (not merely investigate completed attacks) demands that the agency engage in broad intelligence-collection activities within the United States— activities that can threaten fundamental freedoms. This Article argues that strategies derived from administrative law principles can help alleviate the tendency of threat-prevention efforts to erode civil liberties. The fundamental problem this Article tackles is that the traditional governance mechanisms we rely upon to protect individual rights are ineffective in the domestic …

Standing At A Constitutional Divide: Redefining State And Federal Requirements For Initiatives After Hollingsworth V. Perry, Scott L. Kafker, David A. Russcol

Washington and Lee Law Review

In Hollingsworth v. Perry, the Supreme Court denied standing to proponents of the California initiative prohibiting same-sex marriage, who wished to appeal a federal district court judge’s decision declaring the initiative unconstitutional. As suggested by the dissent, Hollingsworth has severe consequences for the twenty-four states in which the people can bypass elected officials and legislate directly through the initiative. The Supreme Court has established a clear constitutional divide between state and federal standing requirements for initiatives. Whereas states provide generous standing to proponents so officials do not exclusively control the defense of the people’s initiative process, the Supreme Court …