Digital Commons Network^™

Multiple Roles For Hoxa3 In Regulating Thymus And Parathyroid Differentiation And Morphogenesis In Mouse, Jena L. Chojnowski, Kyoko Masuda, Heidi A. Trau, Kirk Thomas, Mario Capeechi, Nancy R. Manley

Natural Sciences Faculty Publications

Hoxa3 was the first Hox gene to be mutated by gene targeting in mice and is required for the development of multiple endoderm and neural crest cell (NCC)-derived structures in the pharyngeal region. Previous studies have shown that the Hoxa3 null mutant lacks third pharyngeal pouch derivatives, the thymus and parathyroids by E18.5, and organ-specific markers are absent or downregulated during initial organogenesis. Our current analysis of the Hoxa3 null mutant shows that organ-specific domains did undergo initial patterning, but the location and timing of key regional markers within the pouch, including Tbx1, Bmp4 and Fgf8, were altered. …

Nutrition Education Curriculum For The Adolescent Girls Empowerment Program (Agep), Population Council

Poverty, Gender, and Youth

The Adolescent Girls Empowerment Program (AGEP) in rural and urban Zambia aims to build social, health, and economic assets of adolescent girls. A safe spaces component is at the core of AGEP. Girls groups, under the guidance of a female mentor from the same community, provide a safe and supportive learning environment. The meetings are critical in building social assets for vulnerable girls—including friendships, self-esteem, trusting relationships with adults, and social support. The training content over the course of the year varies from sexual and reproductive health and life skills to financial education and nutrition training. This collection is focused …

Enhancing Livelihood Opportunities For Young Women In Rural Upper Egypt: The Neqdar Nesharek Program, Nada Ramadan, Nahla G. Abdel-Tawab, Khaled El Sayed, Rania Roushdy

Poverty, Gender, and Youth

During the 30+ years that the Population Council has been operating in Egypt, Council researchers have examined many facets of young people’s lives, including conducting nationally representative surveys in 1997, 2009, and 2014. This research has documented the marginalization of Egyptian women in the public sphere, including the labor market, as well as gender inequities in mobility and access to schooling. Neqdar Nesharek is a social and economic empowerment program that evolved in response to this research and from the Council’s experience over the last few years working closely with out-of-school girls in Upper Egypt via the Ishraq program. The …

Highlights From The Unicef Adolescent Development And Participation Baseline Study, Sajeda Amin, Ashish Bajracharya, Michelle Chau, Mahesh Puri

Poverty, Gender, and Youth

This document presents highlights from the UNICEF Adolescent Development and Participation (ADAP) Baseline Study in Nepal, which aims to ensure the systematic, ethical, meaningful, and regular participation of adolescents and focuses on vulnerable and disadvantaged groups. The program aims to empower adolescents, especially girls, to initiate and sustain activities and interventions that create positive transformation in their families, communities, and society, and bring about realization of their rights. The Population Council and partners led a study to develop a research design and implement a baseline survey to inform UNICEF’s ADAP program. The primary aim is to inform the program with …

Public Health Law & Equal Access To Justice In Rural America, Linda L. Chezem

South Dakota Law Review

No abstract provided.

America, Land Of The Free And Home Of The Bullies: An Argument For Workplace Bullying Laws In Professional Sports, Cathryn Copeland Wood

SMU Law Review

No abstract provided.

The American Bar Association And The Rule Of Law, James R. Silkenat

SMU Law Review

No abstract provided.

National “Harmony”: An Inter-Branch Constitutional Principle And Its Application To Diversity Jurisdiction, Jesse M. Cross

Nebraska Law Review

I. Introduction

II. Theories of Diversity Jurisdiction: A Historical Overview

III. Diversity Jurisdiction and National Harmony ... A. “Harmony” in the Age of the Enlightenment ... B. “Interests” in a Harmonious System ... C. “Harmony” as an Inter-Branch Principle

IV. Harmony and the Body Politic

V. Constitutional Text: Between, With, and Among

VI. Purpose: Geographically Commensurate Government

VII. National Harmony and State Court Bias

VIII. Implications ... A. The Purpose of Diversity Jurisdiction ... B. Federal Court Personal Jurisdiction ... C. State Court Personal Jurisdiction ... D. The Class Action Fairness Act of 2005

Less Is More: Applying A Modified Reasonable Compensation Standard To Eliminate The Inconsistencies Among The Payroll Tax Bases And The Net Investment Income Tax Base Under The Affordable Care Act, John S. Treu

Nebraska Law Review

The original policy for the implementation of payroll taxes was to impose a tax on wages as both a funding mechanism for, and a limitation to, qualifying for social security. However, the self-employment tax base developed severe inconsistencies with this original policy and among different tax entities by including certain returns on capital investments in the tax base. At present, different payroll tax obligations arise for similarly situated taxpayers based solely on how business owners elect to be taxed under the check-the-box regulations. These inconsistencies resulted from misguided efforts by Congress and the Treasury to view the payroll tax base …

Activating The Expression Of Human K-Rasg12d Stimulates Oncogenic Transformation In Transgenic Goat Fetal Fibroblast Cells, J. Gong, Zhongde Wang, I. Polejaeva, R. Salgia, C. Kao, T. Chen, L. Chen

Animal, Dairy, and Veterinary Science Faculty Publications

Humane use of preclinical large animal cancer models plays a critical role in understanding cancer biology and developing therapeutic treatments. Among the large animal candidates, goats have great potentials as sustainable sources for large animal cancer model development. Goats are easier to handle and cheaper to raise. The genome of the goats has been sequenced recently. It has been known that goats develop skin, adrenal cortex, breast and other types of cancers. Technically, goats are subject to somatic cell nuclear transfer more efficiently and exhibit better viability through the cloning process. Towards the development of a goat cancer model, we …

Shuffled Frog Leaping Algorithm Optimization For Ac--Dc Optimal Power Flow Dispatch, Abolfazl Rahiminejad, Arash Alimardani, Behrooz Vahidi, Seyed Hossein Hosseinian

Turkish Journal of Electrical Engineering and Computer Sciences

In this paper, a simple-implemented and reliable AC--DC optimal power flow (OPF) is proposed. Although high-voltage direct current (HVDC) transmission lines are being increasingly used in power systems, new optimization algorithms such as evolutionary and memetic algorithms, which never stick in local minimum, so far have not been implemented in the AC--DC OPF problem. An evolutionary algorithm known as the shuffled frog leaping algorithm (SFLA) is proposed in this paper to solve the OPF dispatch in an AC--DC power system (including both high-voltage alternating current and HVDC transmission lines). The implementation of the AC--DC OPF with these kinds of methods …

Stability Analysis Of Multimachine Thermal Power Systems Using The Nature-Inspired Modified Cuckoo Search Algorithm, Shivakumar Rangasamy, Panneerselvam Manickam

Turkish Journal of Electrical Engineering and Computer Sciences

The stability of modern interconnected thermal power systems is greatly affected by the presence of low-frequency inertial oscillations in the system, due to various forms of disturbances experienced. This paper provides an efficient damping solution to these oscillations based on nature-inspired modified cuckoo search algorithm-based controller design. The proposed controller design is formulated as a parameter optimization problem based on damping ratio and time-domain error deviations. The effectiveness of the proposed damping controller design is illustrated by performing the nonlinear time domain simulations of the test multimachine power systems under various operating conditions and disturbances. Moreover, an exhaustive comparative stability …

The Design Of An Embedded Spinal Cord Stimulator, Fi̇kret Yalçinkaya, Ali̇ Erbaş

Turkish Journal of Electrical Engineering and Computer Sciences

Spinal cord stimulation is a physical therapy methodology utilizing electrical impulses, pulses, or a combination of various standard electrical waveforms to block pain. However, standard forms are not functioning effectively for each illness due to the unique conditions of the patient. Therefore, patient-specific waveforms (or user-defined waveforms) integrated with nondestructive, complete, or partially noninvasive and effective medical instruments to help relieve pain are required. In the literature, 2 different designs have been discussed: the bedside/portable and the implantable/surgical types. This work is introducing a new hybrid type: a portable touch-screen multichannel embedded spinal cord stimulator. This work is made of …

Simulation Of A Flowing Snow Avalanche Using Molecular Dynamics, Deni̇zhan Güçer, Hali̇l Bülent Özgüç

Turkish Journal of Electrical Engineering and Computer Sciences

This paper presents an approach for the modeling and simulation of a flowing snow avalanche, which is formed of dry and liquefied snow that slides down a slope, using molecular dynamics and the discrete element method. A particle system is utilized as a base method for the simulation and marching cubes with real-time shaders are employed for rendering. A uniform grid-based neighbor search algorithm is used for collision detection for interparticle and particle-terrain interactions. A mass-spring model of the collision resolution is employed to mimic the compressibility of the snow and particle attraction forces are put into use between the …

Toxic Element Contamination In Waters From The Massive Sulfide Deposits And Wastes Around Giresun, Turkey, Necati̇ Karakaya, Muazzez Çeli̇k Karakaya

Turkish Journal of Earth Sciences

This study assessed the quality of water polluted with mine drainage waters, some of which is used for drinking and agriculture, in the urban areas of the Giresun region, Turkey. A total of 40 water samples were collected from the main rivers and stream, spring, and drainage waters. All samples were analyzed for physical and chemical parameters. The tectonically controlled massive sulfide deposits hosted in the Maastrichtian-Eocene magmatic rocks are either active or have been abandoned. The main ore mineral assemblages are chalcopyrite, sphalerite, galena, and pyrite. The oxidation of the sulfide minerals in the deposits and wastes has caused …

Early Pleistocene Freshwater Communities And Rodents From The Pasinler Basin (Erzurum Province, North-Eastern Turkey), Davit Vasilyan, Simon Schneider, Memet Sali̇h Bayraktutan, Şevket Şen

Turkish Journal of Earth Sciences

An Early Pleistocene lacustrine faunal assemblage from Pasinler (Erzurum Province, north-eastern Turkey) is described, which encompasses 13 mollusc, 5 fish, 2 amphibian, 1 reptile, and 1 mammal species. The autochthonous freshwater mollusc fauna indicates shallow stagnant waters and a fine-sandy to muddy lake bottom, grown with submersed plants. The fish community (Leuciscus sp., Rutilus sp., Chondrostoma sp., Leuciscinae sp. 1 and 2, and Capoeta sp.) and autochthonous herpetofauna (Latonia sp. and Natrix sp.) provide evidence of a well-oxygenised palaeolake with rich periphyton and partially rocky to gravelly bottom. Moreover, the presence of the terrestrial snail Caspicyclotus cf. akramowsii, the peri- …

First Report Of Sphaeronitid Blastozoans (Echinodermata) In The Middle Ordovician Of The Taurides, Turkey, Elise Nardin, Mehmet Cemal Göncüoğlu, Bertrand Lefebvre

Turkish Journal of Earth Sciences

Articulated echinoderm remains are described for the first time in the Ordovician of Turkey. They occur massively, forming a relatively thick “cystoid bed” within the detrital limestone succession of the Sobova Formation (latest Dapingian–earliest Darriwilian) in the western Taurus Mountains. The “cystoid bed” encompasses a monospecific echinoderm assemblage of densely packed, 3-dimensionally preserved thecae. The presence of numerous suborganised plates with diplopore respiratory structures suggests probable affinities with sphaeronitid blastozoans. Comparable sphaeronitid dense beds are well known in the early Darriwilian of Baltica, and in the mid Darriwilian of the Middle East and Asian terranes.

Glycine Betaine-Induced Lead Toxicity Tolerance Related To Elevated Photosynthesis, Antioxidant Enzymes Suppressed Lead Uptake And Oxidative Stress In Cotton, Saima Aslam Bharwana, Shafaqat Ali, Muhammad Ahsan Farooq, Naeem Iqbal, Amjad Hameed, Farhat Abbas, Muhammad Sajid Aqeel Ahmad

Turkish Journal of Botany

Anthropogenic activities contaminate soils with heavy metal concentrations including lead (Pb), cadmium (Cd), copper (Cu), and chromium (Cr). Pb has higher potential for ready accumulation, sedimentation, and poisoning of the soil than other heavy metals. The present study was conducted to induce Pb tolerance, in solution culture-grown cotton, by exogenous glycinebetaine (GB) application using 3 levels of Pb (0, 50, and 100 µm) and 2 GB levels (0 and 1 mM). The results revealed that Pb stress decreased gas exchange characteristics (net photosynthetic rate, stomatal conductance, transpiration rate, water use efficiency, chlorophyll, carotenoids, and SPAD value) and the performance of …

Identification Of Stable Sources For Surrogate Traits In Arachis Glabrata And Marker-Trait Association For Tolerance To Water Deficit Stress, Sandip Kumar Bera, Ajay Basapur Chandrashekar, Sneha Patel, Vrajlal Kanji Sojitra, Anil Maurya

Turkish Journal of Botany

Diploid and tetraploid wild relatives of cultivated peanut are genetically diverse, providing rich sources of genetic resources for tapping resistance to various biotic and abiotic stresses. Arachis glabrata Benth. is a tetraploid (2n = 40) rhizomatous species that is reported to be tolerant to water deficit stress. Identification of A. glabrata accessions with high SPAD chlorophyll meter reading (SCMR) and low specific leaf area (SLA) values would be an option for improving water deficit stress tolerance in peanut. An investigation was undertaken to study the genetic diversity of A. glabrata accessions using molecular markers as well as surrogate traits (SLA …

Heavy Metal Accumulation And Genotoxicity Indicator Capacity Of The Lichen Species Ramalina Pollinaria Collected From Around An Iron Steel Factory In Karabük, Turkey, Demet Cansaran Duman, Ersi̇n Altunkaynak, Emi̇ne Sümer Aras

Turkish Journal of Botany

In the present work, Ramalina pollinaria (Westr.) Ach. specimens collected from around an iron steel factory in Karabük were analyzed due to their heavy metal accumulation by atomic absorption spectrometry. The specimens were also evaluated for pollution-induced DNA damage by random amplified polymorphic DNA (RAPD) assay. Genomic template stabilities were calculated from the changes in RAPD profiles and compared with heavy metal content in R. pollinaria. The results obtained from chemical analysis suggest that R. pollinaria is a particularly suitable lichen species for the detection of air quality. Results of RAPD assay showed significant differences in band patterns in R. …

Micropropagation Of An Antidiabetic Medicinal Plant, Artemisia Pallens, Varsha Nitin Nathar, Ghulam Mohiuddin Yatoo

Turkish Journal of Botany

Artemisia pallens Wall. is an important aromatic medicinal plant used as a folk remedy for the treatment of diabetes mellitus. The present study was initiated to explore in vitro propagation of Artemisia pallens using different explants on Murashige and Skoog (MS) media supplemented with varying concentrations and combinations of growth regulators. Highest callogenic response (100%) was shown by shoot tip explants with 2 mg/L 2,4-dichlorophenoxyacetic acid. The highest number of shoots (14.25 ± 1.65) and highest shoot length (4.25 ± 0.47 cm) were observed on MS medium with 3 mg/L kinetin. After 40 days, shoots grown in vitro were transferred …

Root Architecture Adaptation Of Pistacia Atlantica Subsp. Atlantica According To An Increasing Climatic And Edaphic Gradient: Case Of A North-South Transect In Algeria, Abdelkrim Limane, Noria Smail-Saadoun, Amel Belkebir-Boukais, Karima Kissoum-Hamdini

Turkish Journal of Botany

Despite xeric conditions, Pistacia atlantica Desf. subsp. atlantica (Atlas pistachio) succeeds in developing impressive dendrometric dimensions (25-m high, 2-m trunk diameter). It is among the rare spontaneous phanerophytes of the North African steppe. With access to water being the primary condition for survival, we focused on its root system. According to a gradient of increasing climatic and edaphic aridity in Algeria, we recorded different root architectures set up by this tree. We sampled its underlying soil and determined its main physico-chemical characteristics. Root architecture is mainly of the superficial type with more than 60% of roots located in the top …

Spatiotemporal Distribution In Phytoplankton Community With Distinct Salinity Regimes Along The Mandovi Estuary, Goa, India, Suraksha Mohan Pednekar, Vijaya Kerkar, Shivprasad Ganesh Prabhu Matondkar

Turkish Journal of Botany

Seasonal variations in the composition and abundance of phytoplankton were investigated fortnightly at 3 different regions along the Mandovi estuary from June 2007 to May 2008 in relation to salinity and nutrients. A total of 209 species belonging to 7 divisions were identified during the study period. The highest phytoplankton cell density (5.17 × 10^4 cells L^{-1}) and biomass (7.68 mg m^{-3} chlorophyll a) were observed in the upper sections during the nonmonsoon period, while the highest diversity (3.46) was observed in the upper section during the monsoon period. Bacillariophyta was the dominant phytoplankton group at 71% of the total …

Herniaria Caucasica (Caryophyllaceae), Rumex Cyprius (Polygonaceae), And Potentilla Multifida (Rosaceae); 3 New Records For Turkey, Murat Koç, Ergi̇n Hamzaoğlu

Turkish Journal of Botany

Herniaria caucasica Rupr., Rumex cyprius Murb., and Potentilla multifida L. are given as new records for Turkey. The specimens were collected from Van, Mersin, and Kayseri provinces. These new records were compared with similar species in Turkey. Descriptions, distributions, and figures of these new records are given.

Flower Closure In The Field Bindweed (Convolvulus Arvensis): A Field Test Of The Pollination Hypothesis, Pavol Prokop, Dominika Neupauerova

Turkish Journal of Botany

Although the behavioral plasticity of flower traits has received considerable attention, its adaptive value is not thoroughly understood. We experimentally examined flower opening/closure in field bindweed (Convolvulus arvensis), a species with short flower persistence (1 day) in which adaptive responses to pollination were not previously expected. In line with the pollination hypothesis we suggested that flower exposure in this species should respond to pollination. More specifically, we predicted that flower closure in the pollinated flowers would be quicker than that in unpollinated flowers. As predicted, the unpollinated flowers were open for a longer time than the pollinated flowers. There was …

Ellenberg’S Indicator Values For Soil Nitrogen Concentration And Ph In Selected Swamp Forests In The Central Black Sea Region Of Turkey, Burak Sürmen, Hamdi̇ Güray Kutbay, Dudu Duygu Kiliç, Rena Huseyinova, Mahmut Kilinç

Turkish Journal of Botany

Ellenberg developed a system that assigns indicator scores for habitat characteristics of individual plant species. Swamp forests are highly diverse ecological communities and include different plant species, all of which have different ecological requirements. Ellenberg's indicator values (EIVs) were calculated for soil pH and nitrogen (N) concentration in some swamp forest species in the Central Black Sea region of Turkey. In this study, the EIVs for soil pH were usually similar in the swamp forest species studied, while some differences were found with respect to EIVs for soil nitrogen concentration. Tolerance values (TVs) of all of the studied species were …

Phytochemical Importance Of Medicinal Plants As Potential Sources Of Anticancer Agents, Himani Raina, Garima Soni, Nupur Jauhari, Neelam Sharma, Navneeta Bharadvaja

Turkish Journal of Botany

The diverse and magnificent plant kingdom of the world is widely known for its medicinal importance. The potential medicinal properties of plant species have contributed significantly in the development of various herbal therapies for a number of diseases across the globe. The benefits of herbal medicine over allopathic medicine have helped medicinal plants to regain their importance in the field of health and medicine. Cancer is one of the major health problems that have widely affected the world's population. There is a great need to combat this disease with better and more effective medication as compared to existing therapies. A …

Subcellular Localization And Developmental Regulation Of Cytosolic, Soluble Pyrophosphatase Isoforms In Arabidopsis Thaliana, Zahi̇de Nesli̇han Öztürk, Steffen Greiner, Thomas Rausch

Turkish Journal of Botany

Pyrophosphate (PP_{I}) is the by-product of several reversible key reactions of primary metabolism. Thus, generated PP_i should be removed by hydrolysis via pyrophosphatases to prevent accumulation and to drive anabolism. In plastids, a plastidic, soluble pyrophosphatase splits PP_i released by ADPG pyrophosphorylase. The cytosolic PP_i pool is believed to be hydrolyzed by tonoplast- and/or Golgi-integral H^{+}-translocating pyrophosphatases. The Arabidopsis thaliana (L.) Heynh. genome encodes 6 soluble pyrophosphatase isoforms (PPas), 1 of which was shown to be localized in plastids. The remaining 5 of those PPas (PPas 1-5) are more similar to each other with highly conserved protein sequences. They all …

Assessment Of Genetic Diversity And Phylogenetic Relationships Of Endangered Endemic Plant Barbarea Integrifolia Dc. (Brassicaceae) In Turkey, Ertuğrul Fi̇li̇z, Etem Osma, Ali̇ Kandemi̇r, Hüseyi̇n Tombuloğlu, Guzi̇n Tombuloglu, Seda Bi̇rbi̇lener, Mehtap Aydin

Turkish Journal of Botany

Barbarea integrifolia DC. (Brassicaceae) is an endangered and endemic species located in Erzincan and Gümüşhane provinces of Turkey. In total, 27 individuals from 2 natural populations were assessed using the random amplified polymorphic DNA polymerase chain reaction (RAPD-PCR) method coupled with sequence analysis of the internal transcribed spacer (ITS1) rDNA region. Genetic accuracy of RAPD-PCR was tested with 25 RAPD primers, and it resulted in 115 clear and reproducible DNA fragments from 13 RAPD primers. Among these, 76 (66.1%) fragments were found to be polymorphic. According to the ITS1 analysis of B. integrifolia populations, the plants exhibited a relatively poor …

Genotoxic Effects Of Zinc Oxide And Titanium Dioxide Nanoparticles On Root Meristem Cells Of Allium Cepa By Comet Assay, Eşref Demi̇r, Nuray Kaya, Bülent Kaya

Turkish Journal of Biology

Nanogenotoxicity is an emergent field, relevant for estimating the potential genotoxic risk of nanomaterials. In this study we investigated the genotoxic potential of zinc oxide (ZnO, Keywords: Zinc oxide nanoparticles, titanium dioxide nanoparticles, Allium cepa, comet assay, genotoxicity, DNA damage