Digital Commons Network^™

In Vivo Identification Of Eugenol-Responsive And Muscone-Responsive Mouse Odorant Receptors, Timothy S. Mcclintock, Kaylin Adipietro, William B. Titlow, Patrick Breheny, Andreas Walz, Peter Mombaerts, Hiroaki Matsunami

Physiology Faculty Publications

Our understanding of mammalian olfactory coding has been impeded by the paucity of information about the odorant receptors (ORs) that respond to a given odorant ligand in awake, freely behaving animals. Identifying the ORs that respond in vivo to a given odorant ligand from among the ∼1100 ORs in mice is intrinsically challenging but critical for our understanding of olfactory coding at the periphery. Here, we report an in vivo assay that is based on a novel gene-targeted mouse strain, S100a5-tauGFP, in which a fluorescent reporter selectively marks olfactory sensory neurons that have been activated recently in vivo. Because each …

Um Alumnus Honored By Navy For Science And Technology Achievements, Staff Report

University of Mississippi News

Kerry Commander receives National Defense Industrial Association Bronze Medal

Data Documentation & Metadata, Sai Deng

Faculty Scholarship and Creative Works

No abstract provided.

Using Phylogenetically-Informed Annotation (Pia) To Search For Light-Interacting Genes In Transcriptomes From Non-Model Organisms, Daniel L. Speiser, Molly S. Pankey, Alexander K. Zaharoff, Barbara A. Battelle, Heather D. Bracken-Grissom, Jesse W. Breinholt, Seth M. Bybee, Thomas W. Cronin, Anders Garm, Annie R. Lindgren, Nipam H. Patel, Megan L. Porter, Meredith E. Protas, Ajna S. Rivera, Jeanne M. Serb, Kirk S. Zigler, Keith A. Crandall, Todd H. Oakley

Biology Faculty Publications and Presentations

Background: Tools for high throughput sequencing and de novo assembly make the analysis of transcriptomes (i.e. the suite of genes expressed in a tissue) feasible for almost any organism. Yet a challenge for biologists is that it can be difficult to assign identities to gene sequences, especially from non-model organisms. Phylogenetic analyses are one useful method for assigning identities to these sequences, but such methods tend to be time-consuming because of the need to re-calculate trees for every gene of interest and each time a new data set is analyzed. In response, we employed existing tools for phylogenetic analysis to …

Host, Pathogen, And Environmental Characteristics Predict White-Nose Syndrome Mortality In Captive Little Brown Myotis (Myotis Lucifugus), Joseph S. Johnson, Deeann M. Reeder, James W. Mcmichael Iii

KIP Articles

An estimated 5.7 million or more bats died in North America between 2006 and 2012 due to infection with the fungus Pseudogymnoascus destructans (Pd) that causes white-nose syndrome (WNS) during hibernation. The behavioral and physiological changes associated with hibernation leave bats vulnerable to WNS, but the persistence of bats within the contaminated regions of North America suggests that survival might vary predictably among individuals or in relation to environmental conditions. To investigate variables influencing WNS mortality, we conducted a captive study of 147 little brown myotis (Myotis lucifugus) inoculated with 0, 500, 5 000, 50 000, or 500 000 Pd …

Glucose Significantly Enhances Enterotoxigenic Escherichia Coli Adherence To Intestinal Epithelial Cells Through Its Effects On Heat-Labile Enterotoxin Production, Prageeth Wijemanne, Rodney A. Moxley

School of Veterinary and Biomedical Sciences: Faculty Publications

The present study tested whether exposure of enterotoxigenic Escherichia coli (ETEC) to glucose at different concentrations in the media results in increased bacterial adherence to host cells through increased heat-labile enterotoxin (LT) production, thereby suggesting the effects are physiological. Porcine-origin ETEC strains grown in Casamino acid yeast extract medium containing different concentrations of glucose were washed and inoculated onto IPEC-J2 porcine intestinal epithelial cells to test for effects on adherence and host cell cAMP concentrations. Consistent with previous studies, all LT+ strains had higher ETEC adherence to IPEC-J2 cells than did LT2 strains. Adherence of the LT2 but not the …

Spartan Daily November 19, 2014, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily (School of Journalism and Mass Communications)

Volume 143, Issue 34

The Parthenon, November 19, 2014, Codi Mohr

The Parthenon

The Parthenon, Marshall University’s student newspaper, is published by students Monday through Friday during the regular semester and weekly Thursday during the summer. The editorial staff is responsible for the news and the editorial content.

Metallopeptides From Design To Catalysis: Structure, Oxidative Activities, And Inhibition Studies Of Designed And Naturally Occurring Metallopeptides, Alaa Hassan Hashim

USF Tampa Graduate Theses and Dissertations

Structural and mechanistic complexities of copper-dioxygen systems have attracted much attention in the field of bioinorganic chemistry, both in model systems and trapped protein intermediates. The research presented herein is focused on model and naturally occurring metallopeptide systems, from its design to catalysis. Copper is used as the coordinating metal ion, with cobalt and zinc as probes for metal binding. The bioinorganic chemistry of copper proteins and its coordination and spectroscopic properties are briefly discussed in chapter 1. The next two chapters are centered on the de novo design of a minimalistic metallopeptide system with an amino acid sequence of …

Spectrum, Volume 33, Issue 9, Sacred Heart University

Newspapers (Obelisk & Spectrum)

Highlights include: Sacred Heart football defeats Bryant taking home NEC trophy for second year in a row -- Students compete in New York College Fed Challenge, a competition between universities about economic forecasting -- Drugs, sexting, and partying seen in younger children with high school students partying like college kids -- 5th annual turkey drive sets high goals -- Sacred Heart welcomes new birthing simulator -- Choir hosts concert against bullying -- Both men's and woman's basketball start off their seasons with victories

“At Freud’S House”, Enid Shomer

Ontario Review

Enid Shomer's poems and stories have appeared in The New Yorker, The Atlantic, The Paris Review, and other journals. Her most recent books are This Close to the Earth, poems (Arkansas, 1992) and Imaginary Men, a collection of stories which won the Iowa Short Fiction Award in 1993. She lives in Gainesville, Florida.

“To Mr. Jefferson On The Occasion Of My ‘Madness,’” “The Campaign Manager Talks Shop”, Jon Davis

Ontario Review

Jon Davis is the author of Dangerous Amusements (OR Press). A chapbook of his prose poems, The Hawk. The Road. The Sunlight After Clouds, is forthcoming from Owl Creek Press. New work has appeared or will be appearing in The Harvard Review, Gulf Coast, and The Prose Poem. He lives in Glorieta, New Mexico, and teaches at the Institute of American Indian Arts.

“Chicken In The Box”, Soo Christiansen

Ontario Review

Soo Christiansen's interest in language has drawn her to study in Paris and Geneva. She is currently working on a master's degree in TESOL (Teaching English to Speakers of Other Languages) at New York University. She lives in Brooklyn and works for the United Nations. "Chicken in the Box" is her first published story.

From The Ghost Of Eden (“Sleeping Paint,” “The Pools,” “The Smell Of Snow”), Chase Twichell

Ontario Review

Chase Twichell most recendy published Perdito (Farrar, Straus & Giroux, 1991). The poems here are from her new manuscript, The Ghost of Eden. She teaches in the Creative Writing Program at Princeton University.

“Wildcats", William Black

Ontario Review

William Black, a native of Northeastern Pennsylvania, is completing an MFA at the University of Alabama. "Wildcats" is his first published story.

Eagles Circle The Drum, Mark Shaw

Theses

Mark Shaw’s Eagles Circle the Drum: A Novel My thesis, for the Master of Fine Arts program at the University of Missouri—St. Louis, is a Native American Literary Novel. When Jimmy Moses—a member of the Stockbridge-Munsee Band of Mohican Nation—dies, his mother chooses to have a Christian funeral instead of an American Indian burial ceremony. The reservation community becomes upset, particularly Johnny Bear Moses, her son and Jimmy’s older brother. The novel shifts between various points of view, including Reylene Fisherman, the mother; Johnny Bear; and his daughter, Akasha. These three major characters represent a different opinion of creed and …

Inside The Uconn Libraries, Volume 1, Number 1

UConn Libraries Newsletter

page 1 J.W. "Jack" Swanberg

On Track with an Eminent Railroad Historian, Collector, and Donor

page 2 Message from the Vice Provost Martha Bedard

page 3 Professor Emeritus Rudy J. Favretti

Noted Historic Landscape Architect Has Sights on Mansfield's Past

page 4 Stanley L. Nash

Professor Emeritus Honors Libraries with Gift of Books on Hebrew and Israeli Literature

page 6 Events: Northeast Children's Literature Collection Reception

page 7 Winter Art Exhibits

From Transylvania to Tolland: the Art of Liviu Cupceancu

Current Illustration and Photography from UConn's Faculty in Art and Art History

Illustration - Cora Lynn Deibler, Alison Paul

Photography …

Bringing The U. To You, Tracey Bentley

UNH Today Archive

No abstract provided.

The Utah Statesman, November 18, 2014, Utah State University

The Utah Statesman

Weekly student newspaper of Utah State University in Logan.

The Advocate, November 18, 2014, Minnesota State University Moorhead

The Advocate

No abstract provided.

Body Composition Changes Associated With Fasted Versus Non-Fasted Aerobic Exercise, Brad Jon Schoenfeld, Alan Albert Aragon, Colin D. Wilborn, James W. Krieger, Gul T. Sonmez

Publications and Research

It has been hypothesized that performing aerobic exercise after an overnight fast accelerates the loss of body fat. The purpose of this study was to investigate changes in fat mass and fat-free mass following four weeks of volume-equated fasted versus fed aerobic exercise in young women adhering to a hypocaloric diet. Twenty healthy young female volunteers were randomly assigned to 1 of 2 experimental groups: a fasted training (FASTED) group that performed exercise after an overnight fast (n = 10) or a post-prandial training (FED) group that consumed a meal prior to exercise (n = 10). Training consisted of 1 …

The Formin Fmnl3 Assembles Plasma Membrane Protrusions That Participate In Cell–Cell Adhesion, Timothy J. Gauvin, Lorna E. Young, Henry N. Higgs

Dartmouth Scholarship

FMNL3 is a vertebrate-specific formin protein previously shown to play a role in angiogenesis and cell migration. Here we define the cellular localization of endogenous FMNL3, the dynamics of GFP-tagged FMNL3 during cell migration, and the effects of FMNL3 suppression in mammalian culture cells. The majority of FMNL3 localizes in a punctate pattern, with >95% of these puncta being indistinguishable from the plasma membrane by fluorescence microscopy. A small number of dynamic cytoplasmic FMNL3 patches also exist, which enrich near cell–cell contact sites and fuse with the plasma membrane at these sites. These cytoplasmic puncta appear to be part of …

Renowned Pharmacognosist To Present Waller Lecture, Erin Garrett

University of Mississippi News

A. Douglas Kinghorn returns to Ole Miss to discuss collaborative pharmaceutical research

Mda-9/Syntenin Regulates Differentiation And Angiogenesis Programs In Head And Neck Squamous Cell Carcinoma, Regina A. Oyesana, Shilpa Bhatia, Mitchell E. Menezes, Catherine I. Dumur, Karan P. Singh, Sejong Bae, Dean A. Troyer, Robert B. Wells, Edward R. Sauter, David Sidransky, Paul B. Fisher, Oliver J. Semmes, Santanu Dasgupta

School of Medical and Biological Sciences Faculty Publications and Presentations

Little is known about the molecular pathways regulating poor differentiation and invasion of head and neck squamous cell carcinoma (HNSCC). In the present study, we aimed to determine the role of MDA-9/Syntenin, a metastasis associated molecule in HNSCC tumorigenesis. Elevated MDA-9/Syntenin expression was evident in 67% (54/81) primary HNSCC tumors (p=0.001-0.002) and 69% (9/13) pre-neoplastic tissues (p=0.02-0.03). MDA-9/Syntenin overexpression was associated with the stage (p=0.001), grade (p=0.001) and lymph node metastasis (p=0.0001). Silencing of MDA-9/Syntenin in 3 poorly differentiated HNSCC cell lines induced squamous epithelial cell differentiation, disrupted angiogenesis and reduced tumor growth in vitro and in vivo. We confirmed …

The New Hampshire, Vol. 104 [105], No. 19 (Nov. 18, 2014), The New Hampshire

The New Hampshire Print Edition

An independent student produced newspaper from the University of New Hampshire. This volume was printed as 104, but it is the 105th volume in the series. This was corrected in pencil.

The Pathological Effects Of Ccr2+ Inflammatory Monocytes Are Amplified By An Ifnar1-Triggered Chemokine Feedback Loop In Highly Pathogenic Influenza Infection, Sue-Jane Lin, Ming Lo, Rei-Lin Kuo, Shin-Ru Shih, David M. Ojcius, Jean Lu, Chien-Kuo Lee, Hui-Chen Chen, Meei Yun Lin, Chuen-Miin Leu, Chia-Ni Lin, Ching-Hwa Tsai

All Dugoni School of Dentistry Faculty Articles

Background: Highly pathogenic influenza viruses cause high levels of morbidity, including excessive infiltration of leukocytes into the lungs, high viral loads and a cytokine storm. However, the details of how these pathological features unfold in severe influenza infections remain unclear. Accumulation of Gr1 + CD11b + myeloid cells has been observed in highly pathogenic influenza infections but it is not clear how and why they accumulate in the severely inflamed lung. In this study, we selected this cell population as a target to investigate the extreme inflammatory response during severe influenza infection.

Results: We established H1N1 IAV-infected mouse models using …

Extracellular Excystation And Development Of Cryptosporidium: Tracing The Fate Of Oocysts Within Pseudomonas Aquatic Biofilm Systems, Wan Koh, Andrew Thompson, Hann Edwards, Paul Monis, Peta L. Clode

Harold W. Manter Laboratory of Parasitology: Library Materials

Background: Aquatic biofilms often serve as environmental reservoirs for microorganisms and provide them with a nutrient-rich growth environment under harsh conditions. With regard to Cryptosporidium, biofilms can serve as environmental reservoirs for oocysts, but may also support the growth of additional Cryptosporidium stages.

Results: Here we used confocal laser scanning microscopy, scanning electron microscopy (SEM), and flow cytometry to identify and describe various Cryptosporidium developmental stages present within aquatic biofilm systems, and to directly compare these to stages produced in cell culture. We also show that Cryptosporidium has the ability to form a parasitophorous vacuole independently, in a host-free …

Volume 112, Number 11 - Tuesday, November 18, 2014, Saint Mary's College Of California

The Collegian

No abstract provided.

Bibliotherapy: An Approach To Treating Mental Illness In The Classroom, Erin M. Curry

Senior Honors Theses

The prevalence of adolescent mental illness has increased at an alarming rate over the past two decades. Due to a lack of accessible mental health care and the stigmatization of mental illness, parents of children with these disorders are often reluctant to seek help. These children often resort to negative self-coping methods among which include substance abuse, violence, and suicide. These negative self-coping methods have a harmful, lasting impact on the individual as well as the surrounding community.

Bibliotherapy, which harnesses the meditative power of books, can teach helpful coping skills to students with mental illness. When effectively utilized in …

Montana Kaimin, November 18, 2014, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula.