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2013

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X-Linked Mtmr8 Diversity And Evolutionary History Of Sub-Saharan Populations, Damian Labuda, Vania Yotova, Jean-François Lefebvre, Claudia Moreau, Gerd Utermann, Scott M. Williams Nov 2013

X-Linked Mtmr8 Diversity And Evolutionary History Of Sub-Saharan Populations, Damian Labuda, Vania Yotova, Jean-François Lefebvre, Claudia Moreau, Gerd Utermann, Scott M. Williams

Dartmouth Scholarship

The genetic diversity within an 11 kb segment of the MTMR8 gene in a sample of 111 sub-Saharan and 49 non-African X chromosomes was investigated to assess the early evolutionary history of sub-Saharan Africans and the out-of-Africa expansion. The analyses revealed a complex genetic structure of the Africans that contributed to the emergence of modern humans. We observed partitioning of two thirds of old lineages among southern, west/central and east African populations indicating ancient population stratification predating the out of Africa migration. Age estimates of these lineages, older than coalescence times of uniparentally inherited markers, raise the question whether contemporary …

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Sarabia V. State Appellant's Brief 1 Dckt. 41066 Nov 2013

Sarabia V. State Appellant's Brief 1 Dckt. 41066

Not Reported

No abstract provided.

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Collaborative Competitive Intelligence: A Knowledge Base System Approach, Yu Liang Chi, Tsang Yao Chen Nov 2013

Collaborative Competitive Intelligence: A Knowledge Base System Approach, Yu Liang Chi, Tsang Yao Chen

Business and Information Technology Faculty Research & Creative Works

This study develops a collaborative decision support system to enhance the enterprise competitive intelligence (CI) decision process. A CI knowledge model is constructed by identifying concepts of and relations among instance types, decision models, rules of thumb, and weighting of organization functions. The system consists of: 1) a Domain Ontology of concepts and instances to express the knowledge categorization structure; 2) a Task Ontology to express an objective-oriented knowledge framework to express the combination of questions; and 3) Semantic Rules to develop the logical steps for problem solving. The case experiment results of high Decision Correctness Rate and Departmental Weighting …

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Differential Effects Of Short-Chain Fatty Acids On Motility Of Guinea Pig Proximal And Distal Colon, Norman Hurst Nov 2013

Differential Effects Of Short-Chain Fatty Acids On Motility Of Guinea Pig Proximal And Distal Colon, Norman Hurst

Theses and Dissertations

NTRODUCTION: Colonic bacteria produce short-chain fatty acids (SCFAs) by fermentation of dietary carbohydrates and fiber. The production of SCFAs is greatest in proximal colon where propulsion is likely to be highly dependent on chemical/nutrient stimuli. Unabsorbed SCFAs entering the distal colon are likely to modify peristalsis initiated by fecal pellet-induced distension. AIM: To determine the effect of individual SCFAs on propulsive contractions in guinea pig proximal colon and on pellet propulsion in distal colon. METHODS: Proximal colon was excised, cannulated and placed in Krebs buffer in an organ bath. After equilibration, the colon was distended with 1ml of Krebs buffer …

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Experimental Determination And Equation Of State Modeling Of High-Pressure Fluid Behavior, Yue Wu Nov 2013

Experimental Determination And Equation Of State Modeling Of High-Pressure Fluid Behavior, Yue Wu

Theses and Dissertations

High-pressure solution behavior such as density and phase behavior is a critical fundamental property for the design and optimization of various chemical processes, such as distillation and extraction in the production and purification of oils, polymers, and other natural materials. In this PhD study, solution behavior data are experimentally determined and equation of state (EoS) modeled for n-hexadecane, n-octadecane, n-eicosane, methylcyclohexane, ethylcyclohexane, cis-1,2-dimethylcyclohexane, cis-1,4-dimethylcyclohexane, trans-1,4-dimethylcyclohexane, o-xylene, m-xylene, p-xylene, and 2-methylnaphthalene at temperatures to 525 K and pressures to 275 MPa. A variable-volume view cell coupled with a linear variable differential transformer is used for the high-pressure determination. The reported density …

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Regularization Methods For Predicting An Ordinal Response Using Longitudinal High-Dimensional Genomic Data, Jiayi Hou Nov 2013

Regularization Methods For Predicting An Ordinal Response Using Longitudinal High-Dimensional Genomic Data, Jiayi Hou

Theses and Dissertations

Ordinal scales are commonly used to measure health status and disease related outcomes in hospital settings as well as in translational medical research. Notable examples include cancer staging, which is a five-category ordinal scale indicating tumor size, node involvement, and likelihood of metastasizing. Glasgow Coma Scale (GCS), which gives a reliable and objective assessment of conscious status of a patient, is an ordinal scaled measure. In addition, repeated measurements are common in clinical practice for tracking and monitoring the progression of complex diseases. Classical ordinal modeling methods based on the likelihood approach have contributed to the analysis of data in …

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Kingsley V. Blades Respondent's Brief Dckt. 41302 Nov 2013

Kingsley V. Blades Respondent's Brief Dckt. 41302

Not Reported

No abstract provided.

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November 25, 2013: Rugby Championships, Accreditation Team Visits Seba, Improved Campus Post Office, Saint Mary's College Of California Nov 2013

November 25, 2013: Rugby Championships, Accreditation Team Visits Seba, Improved Campus Post Office, Saint Mary's College Of California

SMC Bulletin 2013-2020

No abstract provided.

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"Dae Scotsmen Dream O 'Lectric Leids?" Robert Crawford's Cyborg Scotland, Alexander Burke Nov 2013

"Dae Scotsmen Dream O 'Lectric Leids?" Robert Crawford's Cyborg Scotland, Alexander Burke

Theses and Dissertations

This thesis applies a Cybernetic interpretation to a selection of poetry by the Scottish Informationist poet Robert Crawford, drawn mostly from two collections: A Scottish Assembly (1990) and Sharawaggi: Poems in Scots (1990). Crawford is contextualized by observing the poetic influences of Robert Burns, John Davidson, and Hugh MacDiarmid, as well as the philosophical influence of George Elder Davie’s The Democratic Intellect. This paper argues that, in response to the Two Cultures hypothesis put forth by C. P. Snow and the widely-held belief that Scotland is irrevocably fractured, the shifting boundaries of the many disparate Scottish cultures are mediated by …

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The Prioritization Of Student Mental Health In The School Setting: Secondary Administrators' And Educators' Knowledge Of Adolescent Suicidal Risk Factors And Warning Signs, Chiquita Elliott Nov 2013

The Prioritization Of Student Mental Health In The School Setting: Secondary Administrators' And Educators' Knowledge Of Adolescent Suicidal Risk Factors And Warning Signs, Chiquita Elliott

Theses and Dissertations

This study investigated the knowledge level of secondary building-level administrators and secondary teachers regarding adolescent suicidal risk factors and warning signs. Additionally, this study contributed a social mediation component, to explore whether educators believe that they have the potential to be change agents for youth in their school communities. Three hundred forty-three participants (318 teachers, 18 assistant principals and 7 principals) from the middle and high schools in a local public school district in the Mid-Atlantic Region of the United States completed a survey pertaining to information on adolescent suicide. Data analyses were conducted through detailed cross-tabulations and analysis of …

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Lapatinib And Sorafenib Kill Gbm Tumor Cells In A Greater Than Additive Manner, Seyedmehrad Tavallai Nov 2013

Lapatinib And Sorafenib Kill Gbm Tumor Cells In A Greater Than Additive Manner, Seyedmehrad Tavallai

Theses and Dissertations

Glioblastoma multiforme (GBM) is the most common and malignant brain tumor in adults, affecting thousands of people worldwide every year, with a life expectancy, post diagnosis of 12 months. Surgery, radiotherapy and chemotherapy together, result in an overall mean survival not exceeding 15 months. Targeted therapeutic agents sorafenib, an oral multi kinase inhibitor, and lapatinib, an epidermal growth factor receptor (EGFR) inhibitor, used in combination have been shown to kill GBM cells be through inhibition of major growth mediating signaling pathways that are frequently over expressed in gliomas, including mitogen-activated protein kinase (MAPK) and phosphatidylinositol 3-kinase/ protein kinase B (PI3K/AKT). …

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Sirt6 And Premature Aging Of Hutchinson-Gilford Progeria Syndrome Fibroblasts., Helal Endisha Nov 2013

Sirt6 And Premature Aging Of Hutchinson-Gilford Progeria Syndrome Fibroblasts., Helal Endisha

Theses and Dissertations

The genetic disease Hutchinson-Gilford Progeria Syndrome (HGPS) arises from a de novo single nucleotide mutation (1824CàT) in the LMNA gene. As a result, the mutated lamin A protein (progerin) remains farnesylated and permanently attached to the nuclear membrane. Progerin accumulates and deforms the nuclear membrane leading to an array of cellular abnormalities driving the cells to enter a state of permanent cell-cycle arrest early on in replicative age i.e. premature cellular senescence. Cellular senescence has been extensively studied as one of the contributing factors to aging in HGPS patients and other age-related diseases. There has also been evidence to show …

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Variation And Modulation Of Micrornas In Prostate Cancer And Biological Fluids, Sarah Seashols Nov 2013

Variation And Modulation Of Micrornas In Prostate Cancer And Biological Fluids, Sarah Seashols

Theses and Dissertations

Prostate cancer is the second-most diagnosed and fatal carcinoma for males in the United States, and better diagnostic markers and potential therapies are needed. microRNAs are small, single-stranded RNA molecules that affect protein expression at the translational level, and dysregulation can dramatically affect cell metabolism. Comparison of 736 microRNA expression levels between the poorly metastatic SV40T immortalized prostate epithelial cell line P69 to its highly tumorigenic and metastatic subline M12 identified 231 miRs that were overexpressed and 150 miRs that showed loss of expression in the M12 cell line. Further evaluation of fourteen identified miRs was accomplished using other prostate …

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The Eastern Echo, November 25, 2013, Eastern Michigan University Nov 2013

The Eastern Echo, November 25, 2013, Eastern Michigan University

EMU Student Newspaper: The Normal News & The Eastern Echo

No abstract provided.

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Brief Of Authors Rodolfo Acuña, Bill Bigelow, Richard Delgado, And Jean Stefancic As Amici Curiae In Support Of Appellants, Counsel For Amici Curiae Nov 2013

Brief Of Authors Rodolfo Acuña, Bill Bigelow, Richard Delgado, And Jean Stefancic As Amici Curiae In Support Of Appellants, Counsel For Amici Curiae

Fred T. Korematsu Center for Law and Equality

Fighting Arizona's Attack on Ethnic Studies - Maya Arce, et al. v. John Huppenthal, et. al

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Amici Curiae Brief On Behalf Of Chief Earl Warren Institute On Law And Social Policy, And The Anti-Defamation League, In Support Of Plaintiffs-Appellants, Counsel For Amici Curiae Nov 2013

Amici Curiae Brief On Behalf Of Chief Earl Warren Institute On Law And Social Policy, And The Anti-Defamation League, In Support Of Plaintiffs-Appellants, Counsel For Amici Curiae

Fred T. Korematsu Center for Law and Equality

Fighting Arizona's Attack on Ethnic Studies - Maya Arce, et al. v. John Huppenthal, et. al

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Brief Of Amicus Curiae Latina And Latino Critical Legal Theory, Inc. Supporting Plaintiffs-Appellants Urging Reversal, Counsel For Amici Curiae Nov 2013

Brief Of Amicus Curiae Latina And Latino Critical Legal Theory, Inc. Supporting Plaintiffs-Appellants Urging Reversal, Counsel For Amici Curiae

Fred T. Korematsu Center for Law and Equality

Fighting Arizona's Attack on Ethnic Studies - Maya Arce, et al. v. John Huppenthal, et. al

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Dean's Spotlight November 25, 2013, Seattle University School Of Law Dean Nov 2013

Dean's Spotlight November 25, 2013, Seattle University School Of Law Dean

Dean's Spotlight

No abstract provided.

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Citations Nov 2013

Citations

NASIG Newsletter

No abstract provided.

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Gateway Essay Winners Announced, Tia Patsavas Nov 2013

Gateway Essay Winners Announced, Tia Patsavas

News and Events (Discontinued Series)

No abstract provided.

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In-Situ Study Of E-Beam Al And Hf Metal Deposition On Native Oxide Inp (100), H. Dong, Santosh Kc, A. Azcatl, W. Cabrera, X. Qin, B. Brennan, D. Zhernokletov, K. Cho, R. Wallace Nov 2013

In-Situ Study Of E-Beam Al And Hf Metal Deposition On Native Oxide Inp (100), H. Dong, Santosh Kc, A. Azcatl, W. Cabrera, X. Qin, B. Brennan, D. Zhernokletov, K. Cho, R. Wallace

Faculty Publications

The interfacial chemistry of thin Al (∼3 nm) and Hf (∼2 nm) metal films deposited by electron beam (e-beam) evaporation on native oxide InP (100) samples at room temperature and after annealing has been studied by in situ angle resolved X-ray photoelectron spectroscopy and low energy ion scattering spectroscopy. The In-oxides are completely scavenged forming In-In/In-(Al/Hf) bonding after Al and Hf metal deposition. The P-oxide concentration is significantly decreased, and the P-oxide chemical states have been changed to more P-rich oxides upon metal deposition. Indium diffusion through these metals before and after annealing at 250 °C has also been characterized. …

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Dean Logan's Blog: Professor Michael Burger Wins National Award, Roger Williams University School Of Law Nov 2013

Dean Logan's Blog: Professor Michael Burger Wins National Award, Roger Williams University School Of Law

Law School Blogs

No abstract provided.

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Inefficiency In Exports, Ishrat Husain Dr. Nov 2013

Inefficiency In Exports, Ishrat Husain Dr.

Faculty Research - Newspaper and Magazine Articles

Pakistan’s merchandise exports have declined from 0.18 percent in 1990 to 0.14 percent of the world export market in the last twenty five years. India’s share has tripled from 0.57 percent to 1.78 while Bangladesh’s share has risen from 0.05 percent to 0.14 percent in the same period. Pakistan’s exports, which used to be only one third of India, have fallen to one tenth and Bangladesh, which used to lag behind with its exports being only one third of Pakistan’s in 1990, exceeded our exports level last year. At the turn of the millennium, 97 percent of merchandise exports used …

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Can Distress Tolerance Predict Chronic Worry? Investigating The Relationships Among Worry, Distress Tolerance, Cognitive Avoidance, Psychological Flexibility, Difficulties In Emotion Regulation, And Anxiety Sensitivity, Bethany Anne Sabourin Nov 2013

Can Distress Tolerance Predict Chronic Worry? Investigating The Relationships Among Worry, Distress Tolerance, Cognitive Avoidance, Psychological Flexibility, Difficulties In Emotion Regulation, And Anxiety Sensitivity, Bethany Anne Sabourin

Master's Theses and Doctoral Dissertations

According to the avoidance theory of worry proposed by Borkovec, Alcaine, and Behar (2004), chronic worry functions as an avoidance mechanism, enabling an individual to diminish the physiological experience of anxiety by impeding emotional processing of the fear stimulus. Previous research has revealed significant correlations between chronic worry and difficulties in emotion regulation (Salters-Pedneault et al., 2006) as well as anxiety sensitivity (Floyd, Garfield, & LaSota, 2005). Distress tolerance which is significantly related to anxiety sensitivity (Bernstein, Zvolensky, Vujanovic, & Moos, 2009) is strongly associated with many maladaptive avoidance behaviors (Anestis et al., 2007; Linehan, 1993; Timpano et al., 2009; …

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Me And Goldilocks...Searching For What Is “Just Right” In Trauma Research: An Autoethnography, Rosemary C. Reilly Nov 2013

Me And Goldilocks...Searching For What Is “Just Right” In Trauma Research: An Autoethnography, Rosemary C. Reilly

The Qualitative Report

This is a reflexive account of the tensions and dilemmas emerging from my experience as a woman qualitative researcher researching trauma and tragedy in communities. Framed as an autoethnography, using my conflictual childhood feelings about Goldilocks as an overarching metaphor, I will weave fairy tale and experience into an examination of the impact I can have on individuals, families, and communities in the course in pursuing research. I will attempt to highlight the edges of research culture and ethical conduct, the politics of trespass and the rights of individuals and communities while trying to discover what is “just right.”

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Perceptions Of Elementary Teachers Who Educate Linguistically Diverse Student, Renee Greenfield Nov 2013

Perceptions Of Elementary Teachers Who Educate Linguistically Diverse Student, Renee Greenfield

The Qualitative Report

This study investigated elementary teachers’ perceptions of linguistically diverse students (LDS). Using Sociocultural Theory as a lens, nine elementary teachers responded to a case study dilemma about a LDS. This study was guided by the following question : How do elementary teachers from the same teacher preparation program perceive the LDS they educate? Data were analyzed using qualitative methods, including domain analysis. The majority of teachers associated the following perceptions with the LDS case: concern for the student, use of deficit language to describe student, assumption that the student’s families had limited English proficiency, and difficulties and assumptions surrounding the …

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Valuing Evaluation: Why Should We Develop An Evaluation Culture?, Martha M. Snyder Nov 2013

Valuing Evaluation: Why Should We Develop An Evaluation Culture?, Martha M. Snyder

The Qualitative Report

Evaluation is an important element of any living system. By doing an evaluation, we can systematically review whether a program, service, or event is meeting the needs and goals of a particular individual or group. In Everyday Evaluation on the Run: The User - Friendly Introductory Guide to Effective Evaluation, author Yoland Wadsworth introduces the rationale, concepts, procedures, and tools that are needed to reflect on our everyday activities and develop a culture of evaluation. Her approachable style and practical advice will appeal to many who are interested in learning how to improve the value they offer in their organizations.

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Liquid Phase Stability Under An Extreme Temperature Gradient, Zhi Liang, Kiran Sasikumar, Pawel Keblinski Nov 2013

Liquid Phase Stability Under An Extreme Temperature Gradient, Zhi Liang, Kiran Sasikumar, Pawel Keblinski

Mechanical and Aerospace Engineering Faculty Research & Creative Works

Using Nonequilibrium Molecular Dynamics Simulations, We Subject Bulk Liquid to a Very High-Temperature Gradient and Observe a Stable Liquid Phase with a Local Temperature Well above the Boiling Point. Also, under This High-Temperature Gradient, the Vapor Phase Exhibits Condensation into a Liquid at a Temperature Higher Than the Saturation Temperature, Indicating that the Observed Liquid Stability is Not Caused by Nucleation Barrier Kinetics. We Show that, Assuming Local Thermal Equilibrium, the Phase Change Can Be Understood from the Thermodynamic Analysis. the Observed Elevation of the Boiling Point is Associated with the Interplay between the "Bulk" Driving Force for the Phase …

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Dense Recordings Reveal Typical And Atypical Development Of Tense Productivity In A Child Previously Diagnosed With Asd, Iris Chin Nov 2013

Dense Recordings Reveal Typical And Atypical Development Of Tense Productivity In A Child Previously Diagnosed With Asd, Iris Chin

Master's Theses

Research on tense development has found that typically developing (TD) children are productive with tense morphology starting between two to two-and-a-half years old. Research findings on children with autism spectrum disorder (ASD), however, have been mixed. To better understand how tense development may differ between TD children and children with ASD, we examined the speech of two children, one TD [Cleo] and one that previously presented symptoms of ASD [Audrey]. This study is novel in its use of the Speechome Recorder, which collects dense audio-video recordings of children’s speech in home environments. We found that both children were productive with …

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Lanthorn, Vol. 48, No. 28, November 25, 2013, Grand Valley State University Nov 2013

Lanthorn, Vol. 48, No. 28, November 25, 2013, Grand Valley State University

Volume 48, July 1, 2013 - June 2, 2014

Lanthorn is Grand Valley State's student newspaper, published from 1968 to the present.

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