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2013

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Irf-3, Irf-5, And Irf-7 Coordinately Regulate The Type I Ifn Response In Myeloid Dendritic Cells Downstream Of Mavs Signaling, Helen M. Lazear, Alissa Lancaster, Courtney Wilkins, Mehul S. Suthar, Albert Huang, Sarah C. Vick, Lisa Clepper, Larissa Thackray, Margaret M. Brassil, Herbert W. Virgin, Janko Nikolich-Zugich, Ashlee V. Moses, Michael Gale Jr., Klaus Fruh, Michael S. Diamond Jan 2013

Irf-3, Irf-5, And Irf-7 Coordinately Regulate The Type I Ifn Response In Myeloid Dendritic Cells Downstream Of Mavs Signaling, Helen M. Lazear, Alissa Lancaster, Courtney Wilkins, Mehul S. Suthar, Albert Huang, Sarah C. Vick, Lisa Clepper, Larissa Thackray, Margaret M. Brassil, Herbert W. Virgin, Janko Nikolich-Zugich, Ashlee V. Moses, Michael Gale Jr., Klaus Fruh, Michael S. Diamond

Open Access Publications

No abstract provided.


Therapeutic Efficacy Of Antibodies Lacking Fcgammar Against Lethal Dengue Virus Infection Is Due To Neutralizing Potency And Blocking Of Enhancing Antibodies, Katherine L. Williams, Soila Sukupolvi-Petty, Martina Beltramello, Syd Johnson, Federica Sallusto, Antonio Lanzavecchia, Michael S. Diamond, Eva Harris Jan 2013

Therapeutic Efficacy Of Antibodies Lacking Fcgammar Against Lethal Dengue Virus Infection Is Due To Neutralizing Potency And Blocking Of Enhancing Antibodies, Katherine L. Williams, Soila Sukupolvi-Petty, Martina Beltramello, Syd Johnson, Federica Sallusto, Antonio Lanzavecchia, Michael S. Diamond, Eva Harris

Open Access Publications

No abstract provided.


Cerebellar White Matter Abnormalities Following Primary Blast Injury In Us Military Personnel, Christine Mac Donald, Ann Johnson, Dana Cooper, Thomas Malone, James Sorrell, Joshua Shimony, Matthew Parsons, Abraham Snyder, Marcus Raichel, Raymond Fang, Stephen Flaherty, Michael Russell, David L. Brody Jan 2013

Cerebellar White Matter Abnormalities Following Primary Blast Injury In Us Military Personnel, Christine Mac Donald, Ann Johnson, Dana Cooper, Thomas Malone, James Sorrell, Joshua Shimony, Matthew Parsons, Abraham Snyder, Marcus Raichel, Raymond Fang, Stephen Flaherty, Michael Russell, David L. Brody

Open Access Publications

No abstract provided.


The Oxytricha Trifallax Macronuclear Genome: A Complex Eukaryotic Genome With 16,000 Tiny Chromosomes, Vincent Magrini, Patrick Minx, Robert S. Fulton, Amy Ly, Sean Mcgrath, Kevin Haub, Richard K. Wilson, Elaine R. Mardis, Et Al Jan 2013

The Oxytricha Trifallax Macronuclear Genome: A Complex Eukaryotic Genome With 16,000 Tiny Chromosomes, Vincent Magrini, Patrick Minx, Robert S. Fulton, Amy Ly, Sean Mcgrath, Kevin Haub, Richard K. Wilson, Elaine R. Mardis, Et Al

Open Access Publications

No abstract provided.


An Upstream Open Reading Frame Modulates Ebola Virus Polymerase Translation And Virus Replication, Reed S. Shabman, Thomas Hoenen, Allison Groseth, Omar Jabado, Jennifer M. Binning, Gaya K. Amarasinghe, Heinz Feldmann, Christopher F. Basler Jan 2013

An Upstream Open Reading Frame Modulates Ebola Virus Polymerase Translation And Virus Replication, Reed S. Shabman, Thomas Hoenen, Allison Groseth, Omar Jabado, Jennifer M. Binning, Gaya K. Amarasinghe, Heinz Feldmann, Christopher F. Basler

Open Access Publications

No abstract provided.


Probabilistic Identification Of Cerebellar Cortical Neurones Across Species, Hui Meng, Dora E. Angelaki, Et Al Jan 2013

Probabilistic Identification Of Cerebellar Cortical Neurones Across Species, Hui Meng, Dora E. Angelaki, Et Al

Open Access Publications

No abstract provided.


Integration Of Mouse And Human Genome-Wide Association Data Identifies Kcnip4 As An Asthma Gene, Robert C. Strunk, Et Al Jan 2013

Integration Of Mouse And Human Genome-Wide Association Data Identifies Kcnip4 As An Asthma Gene, Robert C. Strunk, Et Al

Open Access Publications

No abstract provided.


In Vivo Measurement Of Apolipoprotein E From The Brain Interstitial Fluid Using Microdialysis, Jason D. Ulrich, Jack M. Burchett, Jessica L. Restivo, Dorothy R. Schuler, Philip B. Verghese, Thomas E. Mahan, Gary E. Landreth, Joseph M. Castellano, Hong Jiang, John R. Cirrito, David M. Holtzman Jan 2013

In Vivo Measurement Of Apolipoprotein E From The Brain Interstitial Fluid Using Microdialysis, Jason D. Ulrich, Jack M. Burchett, Jessica L. Restivo, Dorothy R. Schuler, Philip B. Verghese, Thomas E. Mahan, Gary E. Landreth, Joseph M. Castellano, Hong Jiang, John R. Cirrito, David M. Holtzman

Open Access Publications

No abstract provided.


Retrotransposition Of Gene Transcripts Leads To Structural Variation In Mammalian Genomes, Adam D. Ewing, Tracy J. Ballinger, Dent Earl, Broad Institute Genome Sequencing And Analysis Program And Platform, Christopher C. Harris, Li Ding, Richard K. Wilson, David Haussler Jan 2013

Retrotransposition Of Gene Transcripts Leads To Structural Variation In Mammalian Genomes, Adam D. Ewing, Tracy J. Ballinger, Dent Earl, Broad Institute Genome Sequencing And Analysis Program And Platform, Christopher C. Harris, Li Ding, Richard K. Wilson, David Haussler

Open Access Publications

No abstract provided.


Using Geographic Methods To Inform Cancer Screening Interventions For South Asians In Ontario, Canada, Aisha K. Lofters, Piotr Gozdyra, Rebecca Lobb Jan 2013

Using Geographic Methods To Inform Cancer Screening Interventions For South Asians In Ontario, Canada, Aisha K. Lofters, Piotr Gozdyra, Rebecca Lobb

Open Access Publications

No abstract provided.


Developing The Next Generation Of Dissemination And Implementation Researchers: Insights From Initial Trainees, Katherine A. Stamatakis, Wynne E. Norton, Shannon W. Stirman, Cathy Melvin, Ross C. Brownson Jan 2013

Developing The Next Generation Of Dissemination And Implementation Researchers: Insights From Initial Trainees, Katherine A. Stamatakis, Wynne E. Norton, Shannon W. Stirman, Cathy Melvin, Ross C. Brownson

Open Access Publications

No abstract provided.


Using Concept Mapping In The Knowledge-To-Action Process To Compare Stakeholder Opinions On Barriers To Use Of Cancer Screening Among South Asians, Rebecca Lobb, Andrew D. Pinto, Aisha Lofters Jan 2013

Using Concept Mapping In The Knowledge-To-Action Process To Compare Stakeholder Opinions On Barriers To Use Of Cancer Screening Among South Asians, Rebecca Lobb, Andrew D. Pinto, Aisha Lofters

Open Access Publications

No abstract provided.


Neuropathic Midfoot Deformity: Associations With Ankle And Subtalar Joint Motion, David R. Sinacore, David J. Gutekunst, Mary K. Hastings, Michael J. Strube, Kathryn L. Bohnert, Fred W. Prior, Jeffrey E. Johnson Jan 2013

Neuropathic Midfoot Deformity: Associations With Ankle And Subtalar Joint Motion, David R. Sinacore, David J. Gutekunst, Mary K. Hastings, Michael J. Strube, Kathryn L. Bohnert, Fred W. Prior, Jeffrey E. Johnson

Open Access Publications

No abstract provided.


Rnase H2 Roles In Genome Integrity Revealed By Unlinking Its Activities, Hyongi Chon, Justin L. Sparks, Monika Rychlik, Marcin Nowotny, Peter M. Burgers, Robert J. Crouch, Susana M. Cerritelli Jan 2013

Rnase H2 Roles In Genome Integrity Revealed By Unlinking Its Activities, Hyongi Chon, Justin L. Sparks, Monika Rychlik, Marcin Nowotny, Peter M. Burgers, Robert J. Crouch, Susana M. Cerritelli

Open Access Publications

No abstract provided.


A New Structural Framework For Integrating Replication Protein A Into Dna Processing Machinery, Chris A. Brosey, Chunli Yan, Susan E. Tsutakawa, William T. Heller, Robert P. Rambo, John A. Tainer, Ivaylo Ivanov, Walter J. Chazin Jan 2013

A New Structural Framework For Integrating Replication Protein A Into Dna Processing Machinery, Chris A. Brosey, Chunli Yan, Susan E. Tsutakawa, William T. Heller, Robert P. Rambo, John A. Tainer, Ivaylo Ivanov, Walter J. Chazin

Open Access Publications

No abstract provided.


Measuring The Racial Unevenness Of Law School, Jonathan Feingold, Doug Souza Jan 2013

Measuring The Racial Unevenness Of Law School, Jonathan Feingold, Doug Souza

Faculty Scholarship

In "Measuring the Racial Unevenness of Law School," Jonathan Feingold and Doug Souza introduce and analyze the concept of racial unevenness, which refers to the particularized burdens an individual encounters as a result of her race. These burdens, which often arise because an individual falls outside of the racial norm, manifest across a spectrum. At one end lie obvious forms of overt and invidious racial discrimination. At the other end, racial unevenness arises from environmental factors and institutional culture independent from any identifiable perpetrator. As the authors detail, race-dependent burdens can arise in institutions and communities that expressly promote racial …


Multicenter Evaluation Of The Vitek Ms Matrix-Assisted Laser Desorption Ionization-Time Of Flight Mass Spectrometry System For Identification Of Gram-Positive Aerobic Bacteria, Jenna Rychert, Carey-Ann D. Burnham, Maureen Bythrow, Omai B. Garner, Christine C. Ginocchio, Rebecca Jennemann, Michael A. Lewinski, Ryhana Manji, A. Brian Mochon, Gary W. Procop, Sandra S. Richter, Linda Sercia, Lars F. Westblade, Mary Jane Ferraro, John A. Branda Jan 2013

Multicenter Evaluation Of The Vitek Ms Matrix-Assisted Laser Desorption Ionization-Time Of Flight Mass Spectrometry System For Identification Of Gram-Positive Aerobic Bacteria, Jenna Rychert, Carey-Ann D. Burnham, Maureen Bythrow, Omai B. Garner, Christine C. Ginocchio, Rebecca Jennemann, Michael A. Lewinski, Ryhana Manji, A. Brian Mochon, Gary W. Procop, Sandra S. Richter, Linda Sercia, Lars F. Westblade, Mary Jane Ferraro, John A. Branda

Open Access Publications

No abstract provided.


Old Testament Survey, Steelman Library, Rodney White Dr. Jan 2013

Old Testament Survey, Steelman Library, Rodney White Dr.

Syllabus Repository

No abstract provided.


Emerging Roles For Immunomodulatory Functions Of Free Isg15, Jessica A. Campbell, Deborah J. Lenschow Jan 2013

Emerging Roles For Immunomodulatory Functions Of Free Isg15, Jessica A. Campbell, Deborah J. Lenschow

Open Access Publications

No abstract provided.


Surgical Cyst Decortication In Autosomal Dominant Polycystic Kidney Disease, Melissa Millar, Youssef S. Tanagho, Mohammed Haseebuddin, Ralph V. Clayman, Sam B. Bhayani, R. Sherburne Figenshau Jan 2013

Surgical Cyst Decortication In Autosomal Dominant Polycystic Kidney Disease, Melissa Millar, Youssef S. Tanagho, Mohammed Haseebuddin, Ralph V. Clayman, Sam B. Bhayani, R. Sherburne Figenshau

Open Access Publications

No abstract provided.


Introduction To Children's Ministry, Steelman Library, Angel Sims Jan 2013

Introduction To Children's Ministry, Steelman Library, Angel Sims

Syllabus Repository

No abstract provided.


The Role Of Self-Transcendence : A Missing Variable In The Pursuit Of Successful Aging?, Valerie Lander Mccarthy, Jiying Ling, Robert M. Carini Jan 2013

The Role Of Self-Transcendence : A Missing Variable In The Pursuit Of Successful Aging?, Valerie Lander Mccarthy, Jiying Ling, Robert M. Carini

Faculty and Staff Scholarship

While successful aging is often defined as the absence of disease and disability or as life satisfaction, self-transcendence may also play an important role. The objective of this research was to test a nursing theory of successful aging proposing that transcendence and adaptation predict successful aging. In this cross-sectional exploratory study, a convenience sample of older adults (N = 152) were surveyed about self-transcendence, proactive coping, and successful aging. Using hierarchical multiple regression, self-transcendence, proactive coping, and all control variables (i.e., sex, race, perceived health, place of residence) together explained 50% of the variance in successful aging (p < 0.001). However, proactive coping alone was not a significant predictor of successful aging. Thus, this study did not support the theory that both self-transcendence and proactive coping predict successful aging. Self-transcendence was the only significant contributor to this multidimensional view of successful aging. Self-transcendence is an important variable in the pursuit of successful aging, which merits further investigation.


Bowling Online : The Internet And The New Social Capital., Jason Gainous, Kevin M. Wagner Jan 2013

Bowling Online : The Internet And The New Social Capital., Jason Gainous, Kevin M. Wagner

Faculty and Staff Scholarship

The decline thesis proponents in the social capital literature have largely ignored the fastest growing venue for new social capital formation – the Internet. We argue that the Internet is making a larger impact than the current research acknowledges. Using survey data from the Pew Internet & American Life Project combined with a survey of college students, we confirm a strong positive relationship between online social networking and political participation. Further, we present evidence that, at least in 2008 election, there was a bias toward voting for Democrats among those who utilized online social networking services including Facebook and Twitter. …


Civic Education And Democratic Capacity : How Do Teachers Teach And What Works?, Allison M. Martens, Jason Gainous Jan 2013

Civic Education And Democratic Capacity : How Do Teachers Teach And What Works?, Allison M. Martens, Jason Gainous

Faculty and Staff Scholarship

Objectives In recent years, political scientists have found that civic education improves the democratic capacity of students, yet little research has been done to date on how and why civic education works when it does. In this study, we go inside the classroom to explore how teachers teach civics to find out what works best at preparing young people for responsible, democratic citizenship. Methods Using a survey of American students, principals, and teachers, we examine the varied instructional methods being employed by social studies teachers in ninth-grade classrooms across the country to determine which methods and which combinations of methods …


Central Asia, The Shanghai Cooperation Organization, And American Foreign Policy : From Indifference To Engagement., Charles E. Ziegler Jan 2013

Central Asia, The Shanghai Cooperation Organization, And American Foreign Policy : From Indifference To Engagement., Charles E. Ziegler

Faculty and Staff Scholarship

This paper examines U.S. engagement in Central Asia over the past two decades, with specific reference to the Shanghai Cooperation Organization. While alarmist voices occasionally warn of the threat to American interests from China and Russia through the SCO, the organization’s influence appears limited. Washington has engaged it only sporadically, preferring to conduct relations bilaterally with the Central Asian states.


Rethinking Critical Mass In The Federal Appellate Courts., Laura Moyer Jan 2013

Rethinking Critical Mass In The Federal Appellate Courts., Laura Moyer

Faculty and Staff Scholarship

This article draws from critical mass studies of gender in other political institutions to inform an application to the US Courts of Appeals. The results demonstrate the utility of considering court-level aspects of diversity. As mixed-sex panels become more common within a circuit, both male and female judges increasingly support plaintiffs in civil rights claims, though the magnitude of the effect is larger for women. The presence of a female chief judge is also positively associated with pro-plaintiff decisions by men and women in sex discrimination cases.


Diapause And Anhydrobiosis In Embryos Of Artemia Franciscana : Metabolic Depression, Lea Proteins And Water Stress., Steven Handel, Yuvraj Patil, Shumin Li, Nilay Charkraborty, Arpurva Borcar, Michael Menze, Leaf Boswell, Daniel Moore, Mehmet Toner Jan 2013

Diapause And Anhydrobiosis In Embryos Of Artemia Franciscana : Metabolic Depression, Lea Proteins And Water Stress., Steven Handel, Yuvraj Patil, Shumin Li, Nilay Charkraborty, Arpurva Borcar, Michael Menze, Leaf Boswell, Daniel Moore, Mehmet Toner

Faculty and Staff Scholarship

Metabolic depression is typically correlated with extended survival of environmental challenge and energy-limitation in early life stages of various invertebrates and vertebrates. Diapause is an ontogenetically-programmed reduction of development and often metabolism seen in many invertebrates. When embryos of Artemia franciscana enter the state of diapause, the overall metabolic depression is estimated to be greater than 99%. These embryos also contain trehalose and express multiple isoforms of Late Embryogenesis Abundant (LEA) proteins, constituents often present in a number of such anhydrobiotic animals. The mRNA levels for LEA proteins are highest in diapause and post-diapause embryos that possess desiccation tolerance, but …


Assessing Depression In Cancer Patients : A Longitudinal Comparison Of Three Questionnaires., Patrick Possel, Kerstin Knopf Jan 2013

Assessing Depression In Cancer Patients : A Longitudinal Comparison Of Three Questionnaires., Patrick Possel, Kerstin Knopf

Faculty and Staff Scholarship

The article by Johns et al. (1) compares the Hopkins Symptom Checklist 20-item depression scale (HSCL-20) (2), the Short-Form 36 Mental Health Inventory five-item distress scale (MHI-5) (3), and the Patient Health Questionnaire nine-item depression scale (PHQ-9) (4) in 309 adults with cancer in a longitudinal study.


Material Internal Control Weaknesses And Earnings Management In The Post-Sox Environment, Benjamin P. Foster, Trimbak Shastri Jan 2013

Material Internal Control Weaknesses And Earnings Management In The Post-Sox Environment, Benjamin P. Foster, Trimbak Shastri

Faculty and Staff Scholarship

Prior studies found that companies with internal control deficiencies incorporate abnormal accounting accruals into their financial statements. However, these studies did not consider the materiality of abnormal accruals. Abnormal accruals should be within materiality when financial statements receive clean audit opinions. When material internal control weaknesses (MICW) exist, to compensate for additional risk, auditors should apply more audit effort to gain the quantity and quality of evidence necessary to obtain a reasonable degree of assurance to support their audit reports. We find evidence of this because audit fees are significantly higher for MICW companies than those for effective internal controls …


Moral Obligations Of Landowners: An Examination Of Doctrine, Stewart E. Sterk Jan 2013

Moral Obligations Of Landowners: An Examination Of Doctrine, Stewart E. Sterk

Articles

Efficiency concerns generally take center stage in modern discussions of property's institutional foundations. But property's moral dimension has a far longer pedigree. Two of the ten commandments implicitly acknowledge the importance of property. "Thou shalt not steal" has no meaning in the absence of property ownership. Similarly, the command that "thou shalt not covet your neighbor's house" assumes that the house has an owner whose rights merit respect.