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Spinal Morphine But Not Ziconotide Or Gabapentin Analgesia Is Affected By Alternative Splicing Of Voltage-Gated Calcium Channel Cav2.2 Pre-Mrna, Yu-Qiu Jiang, Arturo Andrade, Diane Lipscombe

Publications and Research

Presynaptic voltage-gated calcium CaV2.2 channels play a privileged role in spinal level sensitization following peripheral nerve injury. Direct and indirect inhibitors of CaV2.2 channel activity in spinal dorsal horn are analgesic in chronic pain states. CaV2.2 channels represent a family of splice isoforms that are expressed in different combinations according to cell-type. A pair of mutually exclusive exons in the CaV2.2 encoding Cacna1b gene, e37a and e37b, differentially influence morphine analgesia. In mice that lack exon e37a, which is enriched in nociceptors, the analgesic efficacy of intrathecal morphine against noxious thermal stimuli is reduced. Here we ask if sequences unique …

A Replication Of “The Political Determinants Of Federal Expenditure At The State Level” (Public Choice, 2005), Stratford Douglas, W. Robert Reed

Economics Faculty Working Papers Series

This paper replicates and analyses a study by Hoover and Pecorino (2005) on federal spending in US states. H&P followed on path-breaking research by Atlas et al. (1995) in which evidence was claimed in favour of the “small state effect;” namely, that since every state is represented by two senators, small states have a disproportionate influence relative to their population size. Using H&P’s data, we both replicate their results, and demonstrate strong support for the small state effect when we formally test their predictions. The contribution of this study is that we demonstrate that this empirical support vanishes when we …

Systems Metabolic Engineering Of Microbial Cell Factories For The Synthesis Of Value-Added Chemicals, Arul Mozhy Varman

All Theses and Dissertations (ETDs)

Microbial cell factories offer us an excellent opportunity for the conversion of many different cheaply available raw materials into valuable chemicals. Systems metabolic engineering aims at developing rational strategies for the engineering of microbial hosts by providing global level information of a cell. This dissertation focuses on metabolic engineering, bioprocess modeling and pathway analysis, to develop robust microbial cell factories for the synthesis of value-added chemicals. The following research tasks were completed in this regard.

First, statistical models were developed for the prediction of product yields in engineered microbial cell factories - Saccharomyces cerevisiae and Escherichia coli: Chapter 2). A …

Summary Of In Re Nilsson, 129 Nev. Adv. Op. 101, Keivan Roebuck

Nevada Supreme Court Summaries

The Court determined whether a debtor may claim Nevada’s homestead exemption when he does not reside on the property but his minor children do.

Summary Of Dogra V. Liles, 129 Nev. Adv. Op. 100, Jeff Scarborough

Nevada Supreme Court Summaries

The Court determined three issues: (1) whether a nonresident defendant is subject to personal jurisdiction in Nevada when the sole basis asserted is her adult child’s unilateral act of driving the defendant’s vehicle in Nevada; (2) whether a defendant’s filing of a motion to consolidate in a Nevada court waived her right to object to the court’s exercise of personal jurisdiction over her; and (3) whether an interpleader action filed by a defendant’s car insurance company subjects its insured to personal jurisdiction in Nevada.

Summary Of State V. Kincade, 129 Nev. Adv. Op. 102, Shaina Plaksin

Nevada Supreme Court Summaries

The Court determined whether the district court properly excluded evidence seized pursuant to a search warrant that did not comply with NRS 179.045(5) because it failed to include either a statement of probable cause or the affidavit upon which probable cause was based.

Summary Of Taylor V. Nev. Dept. Of Health And Human Servs., 129 Nev. Adv. Op. 99, Whitney E. Short

Nevada Supreme Court Summaries

The Court determined one issue: whether it is within a hearing officer’s duty to determine the appropriate level of discipline and impose that determination.

Lopez V. State Appellant's Brief Dckt. 40822

Not Reported

No abstract provided.

Electronic And Physical Characterization Of Hydrothermally Grown Single Crystal Tho2, Tony D. Kelly Ii

Theses and Dissertations

Actinide single crystals are important to the fabrication of next generation electronic devices that could possibly have radiation with the atmosphere and surroundings. Th02 single crystals were obtained previous to this work by hydrothermal synthesis. As these crystals were the first of their kind, the geometric and electric structure of the crystals needed to be extracted. The valence and conduction bands were studied in order to ascertain the band gap using ultraviolet photoemission spectroscopy (UPS) and inverse photoemission spectroscopy (IPES). The unoccupied structure was further characterized using x-ray absorption near edge structure (XANES) and relativistic, real-space Green's functions calculations. The …

Real-Time, Multiple Pan/Tilt/Zoom Computer Vision Tracking And 3d Positioning System For Unmanned Aerial System Metrology, Daniel D. Doyle

Theses and Dissertations

The study of structural characteristics of Unmanned Aerial Systems (UASs) continues to be an important field of research for developing state of the art nano/micro systems. Development of a metrology system using computer vision (CV) tracking and 3D point extraction would provide an avenue for making these theoretical developments. This work provides a portable, scalable system capable of real-time tracking, zooming, and 3D position estimation of a UAS using multiple cameras. Current state-of-the-art photogrammetry systems use retro-reflective markers or single point lasers to obtain object poses and/or positions over time. Using a CV pan/tilt/zoom (PTZ) system has the potential to …

December 25, 2013: The Future Of The Secular Outlook, Bruce Ledewitz

Hallowed Secularism

Blog post, “The Future of the Secular Outlook“ discusses politics, theology and the law in relation to religion and public life in the democratic United States of America.

Williams V. Williams Appellant's Brief Dckt. 41261

Not Reported

No abstract provided.

In Re: Friedman's Inc

2013 Decisions

USDC for the District of Delaware

Usa V. Ronald Ottaviano

2013 Decisions

USDC for the District of New Jersey

Nicholas George V. William Rehiel

2013 Decisions

USDC for the Eastern District of Pennsylvania

The Murray Ledger And Times, December 24, 2013, The Murray Ledger And Times

The Murray Ledger & Times

No abstract provided.

Estate Of Andrea Y Arrington V. John Michael

2013 Decisions

USDC for the Eastern District of Pennsylvania

Pnmt As A Novel Marker For Progenitor Cells, Steven Ebert, Karl Pfeifer

UCF Patents

In certain aspects, the present invention provides methods and compositions relating to a Pnmt-positive progenitor cell. In certain aspects, the present invention relates to methods for isolating and transplanting the subject progenitor cells, and methods for treating diseases such as myocardiac injuries and neurodegenerative disorders.

Lebow V. Commercial Tire, Inc. Respondent's Brief Dckt. 41234

Idaho Supreme Court Records & Briefs, All

No abstract provided.

State V. Varela-Tema Respondent's Brief Dckt. 40847

Not Reported

No abstract provided.

Kody’S Big Score In The Challenge To Polygamy Law, Joanna L. Grossman, Lawrence M. Friedman

Hofstra Law Faculty Scholarship

Kody Brown is the star (if that is the word) of Sister Wives, a television reality show. Kody has four “wives” and more than a dozen kids. He is legally married only to the first wife, but claims to be “spiritually married” to the other three. When the show began, they all lived in Lehi, Utah, in a specially designed polygamous house, with separate living quarters for each wife. They now live in Las Vegas, Nevada, where polygamous architecture is not as easy to come by, in adjacent houses around a cul-de-sac. Perhaps the only polygamist in town, Kody …

Reid On Olfaction And Secondary Qualities, Jake Quilty-Dunn

Publications and Research

Thomas Reid is one of the primary early expositors of the “dual-component” theory of perception, according to which conscious perception constitutively involves a non-intentional sensation accompanied by a noninferential perceptual belief. In this paper, I will explore Reid's account of olfactory perception, and of odor as a secondary quality. Reid is often taken to endorse a broadly Lockean picture of secondary qualities, according to which they are simply dispositions to cause sensations. This picture creates problems, however, for Reid's account of how we perceive secondary qualities, including odors. Given Reid's insistence that we come to be aware of odors only …

State V. Hudson Respondent's Brief Dckt. 40655

Not Reported

No abstract provided.

3d Conductive Nanocomposite Scaffold For Bone Tissue Engineering, Aref Shahini, Mostafa Yazdimamaghani, Kenneth J. Walker, Margaret A. Eastman, Hamed Hatami-Marbini, Brenda J. Smith, John L. Ricci, Sundar V. Madihally, Daryoosh Vashaee, Lobat Tayebi

Chemical and Biochemical Engineering Faculty Research & Creative Works

Bone healing can be significantly expedited by applying electrical stimuli in the injured region. Therefore, a three-dimensional (3D) ceramic conductive tissue engineering scaffold for large bone defects that can locally deliver the electrical stimuli is highly desired. In the present study, 3D conductive scaffolds were prepared by employing a biocompatible conductive polymer, ie, poly(3,4-ethylenedioxythiophene) poly (4-styrene sulfonate) (PEDOT:PSS), in the optimized nanocomposite of gelatin and bioactive glass. For in vitro analysis, adult human mesenchymal stem cells were seeded in the scaffolds. Material characterizations using hydrogen-1 nuclear magnetic resonance, in vitro degradation, as well as thermal and mechanical analysis showed that …

Allied General Fire And Sec., Inc. V. St. Luke's Regional Medical Center Appellant's Reply Brief Dckt. 41045

Not Reported

No abstract provided.

Cazier V. Idaho State Dept. Of Health And Welfare Appellant's Brief Dckt. 41255

Not Reported

No abstract provided.

Libya's Implosion And Its Impacts On Children, Lere Amusan

Journal of International Women's Studies

The Arab Spring’s ripple effects on Libya led to the overthrow of Muammar Al-Qaddafi’s government of over four decades. The regime change in Libya was not a smooth adventure. It led to a civil war, which impacted negatively on Libyan children. The seeds of discord that this war sowed in the once considered stable state shall be the focus of this discussion through the employment of descriptive and analytical methods. The contention of this study is that every actor in the civil war disregarded various international treaties that protect children and indigenous peoples during the war. This paper argues that …

Lessons Gleaned From The Political Participation Of Children In Bahrain Uprising, Hae Won Jeong

Journal of International Women's Studies

Reflecting the tension between state sovereignty and human rights, this paper discusses the moral and ethical implications of the political participation and detention of Bahraini children against the backdrop of sectarian geopolitics. Drawing methodological insights from postmodernism, this paper argues that reading of Bahraini children as political subjects are objectified and reified with truth claims, which ascribes them a minoritized status based on age and sect. This paper is interdisciplinary in its approach and is three-pronged: First, it begins by providing a contextual analysis of sectarian politics and dichotomous discourses of national sovereignty and human rights. Secondly, this paper juxtaposes …

Women Lost, Women Found: Searching For An Arab-Islamic Feminist Identity In Nawal El Saadawi’S Twelve Women In A Cell In Light Of Current Egyptian "Spring" Events, Ebtehal Al-Khateeb

Journal of International Women's Studies

Dr. Nawal El Saadawi, an Arab feminist, playwright, novelist, and thinker, has been one of the most controversial literary figures in Arab contemporary literature. In this paper, I examine El Saadawi’s 1984 play Twelve Women in A Cell in light of the ongoing political dissidence that gave birth to the recent Arab Spring and its intricate relation to feminist dissidence. The play published twenty-eight years ago, deals with a bizarre situation that surprisingly and sadly, is still relevant to women’s struggle within Arab-Islamic hegemony. The cell that hosts twelve Egyptian women, in El Saadawi’s play, becomes the Arabic Islamic patriarchal …

Effect Of Nanoparticles On The Biochemical And Behavioral Aging Phenotype Of The Nematode Caenorhabditis Elegans, Andrea Scharf, Annette Piechulek, Anna Von Mikecz

Biological Sciences Faculty Research & Creative Works

Invertebrate animal models such as the nematode Caenorhabditis elegans (C. elegans) are increasingly used in nanotechnological applications. Research in this area covers a wide range from remote control of worm behavior by nanoparticles (NPs) to evaluation of organismal nanomaterial safety. Despite of the broad spectrum of investigated NP-bio interactions, little is known about the role of nanomaterials with respect to aging processes in C. elegans. We trace NPs in single cells of adult C. elegans and correlate particle distribution with the worm's metabolism and organ function. By confocal microscopy analysis of fluorescently labeled NPs in living worms, we identify two …