Digital Commons Network^™

Biological Markers Of Cognition And Error-Detection, Nicholas Edwards, Dawson Hedges

Journal of Undergraduate Research

The purpose of my project was to find factors that might be predictive of cognitive deficits in a college age group of people. After discussing the topic with my mentor, Dawson Hedges, we chose a few broad categories, including family health history, demographics, education, and psychological history. Once we had decided upon these topics, I began looking through the literature to see what questions people had already asked.

The Influence Of Economic Growth, Population, And Fossil Fuel Scarcity On Energy Investments, Enrica De Cian, Fabio Sferra, Massimo Tavoni

Fondazione Eni Enrico Mattei Working Papers

This paper examines the dynamics of energy investments and clean energy Research and Development (R&D) using a scenario-based modeling approach. Starting from the global scenarios proposed in the RoSE model ensemble experiment, we analyze the dynamics of investments under different assumptions regarding economic and population growth as well as availability of fossil fuel resources, in the absence of a climate policy. Our analysis indicates that economic growth and the speed of income convergence across countries matters for improvements in energy efficiency, both via dedicated R&D investments but mostly through capital-energy substitution. In contrast, fossil fuel prices, by changing the relative …

Boaler Working In The Butterfly Conservatory, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Uab Adds Biomedical Sciences Undergraduate Program, Alicia Rohan

Browse All News

No abstract provided.

Perilaku Pencegahan Penyakit Menular Seksual Di Kalangan Wanita Pekerja Seksual Langsung, Dewi Purnamawati

Kesmas

Penyakit menular seksual, merupakan pandemi yang menimbulkan dampak kesehatan, sosial, ekonomi dan politik. Pekerja seks berperan penting dalam peningkatan kasus HIV/AIDS di Indonesia, posisi tawar wanita pekerja seksual langsung yang rendah dalam penggunaan kondom dan perilaku berisiko membuat perluasan penyebaran kasus penyakit menular seksual (infeksi menular seksual dan HIV/AIDS) semakin meningkat. Penelitian ini bertujuan untuk mengetahui secara mendalam perilaku wanita pekerja seksual langsung dalam pencegahan penyakit menular seksual di Kabupaten Karawang. Penelitian ini menggunakan pendekatan kualitatif dengan teknik wawancara mendalam. Informan adalah wanita pekerja seksual langsung, mucikari dan tenaga kesehatan. Dari hasil wawancara mendalam diketahui bahwa hampir semua wanita pekerja …

Apparatus And Method For Growing Biological Organisms For Fuel And Other Purposes, David J. Bayless, Morgan Lefay Vis-Chiasson, Ben J. Stuart, Gregory G. Kremer

Mechanical and Aerospace Engineering Faculty Research & Creative Works

A bioreactor apparatus in which a container has sidewalls, a floor and a ceiling defining a chamber that contains a slurry of water, nutrients and photosynthetic microorganisms. A plurality of optical fibers, each of which has a first end disposed outside the chamber and a second end in the mixture. A light collector spaced from the container has light incident on it and focuses the light onto the first ends of the plurality of optical fibers, thereby permitting the light to be conveyed into the mixture to promote photosynthesis. At least one nozzle is in fluid communication with a source …

Lydria: A Better Way To Manage Conventions And Seminars, Ohio University College Of Arts & Sciences

All Forum Articles

No abstract provided.

Employees, Students Grow Their Own Fruits And Vegetables In Uab Gardens, Reporter Staff

Browse All News

No abstract provided.

Developing The Confocal And Fluorescence Microscopy Techniques To Visualize The Eliposomes Inside Of Cells To Treat Cancer, Tara Pandey, Dr. William Pitt

Journal of Undergraduate Research

Cancer is among the leading causes of death in the world. The goal for this project was to visualize a liposome containing perfluorocarbon emulsion an eLiposome, inside of tumor cells using confocal and fluorescence microscopes. A successful study of this project would help to understand the behavior of cancer cells in the presence of drugs during targeted drug delivery for cancer.

Today - June 25, 2013, Loma Linda University Health

TODAY

Inside this issue:

-- Commencement season for 2013 results in close to 1,400 new Loma Linda University alumni
-- Grand opening held for new Loma Linda Farmer's Market
-- New dentistry professor brings years of clinical experience to students
-- Professor awarded Fulbright scholarship to do research in United Kingdom
-- Dr. and Mrs. Avery Pratt on cancer treatment that makes you feel like a person, not a patient
-- An employee says yes to 'Say N.O.W.' program
-- Healing Hands program provides patients with the opportunity to give back
-- Alumni reconnect during nursing alumni weekend
-- Scenes from …

Use Of Parthenolide Derivatives As Antileukemic And Cytotoxic Agents, Peter A. Crooks, Craig T. Jordan, Xiaochen Wei

Pharmaceutical Sciences Faculty Patents

To view this abstract, please download this patent.

Antibiotic-Bound Poly(Caprolactone) Polymer, Edward Turos, Michelle Leslie

USF Patents

This invention is the design and synthesis of a caprolactone monomer which bears a pendant protected carboxyl group. This monomer has been copolymerized with caprolactone in varying ratios. After polymerization, the protecting group can be removed and an antibiotic can be attached as a new pendant group. The bioactivity of the antibiotic-bound poly(caprolactone) polymer is described.

Epigallocatechin-3-Gallate Crystal Compositions, Michael Zaworotko, Sheshanka Kesani

USF Patents

Crystalline epigallocatechin-3-gallate compositions and methods of use.

Breed Locally, Disperse Globally: Fine-Scale Genetic Structure Despite Landscape-Scale Panmixia In A Fire-Specialist, Jennifer C. Pierson, Fred W. Allendorf, Pierre Drapeau, Michael K. Schwartz

Biological Sciences Faculty Publications

An exciting advance in the understanding of metapopulation dynamics has been the investigation of how populations respond to ephemeral patches that go 'extinct' during the lifetime of an individual. Previous research has shown that this scenario leads to genetic homogenization across large spatial scales. However, little is known about fine-scale genetic structuring or how this changes over time in ephemeral patches. We predicted that species that specialize on ephemeral habitats will delay dispersal to exploit natal habitat patches while resources are plentiful and thus display fine-scale structure. To investigate this idea, we evaluated the effect of frequent colonization of ephemeral …

Model Pengendalian Demam Berdarah Dengue, Ringga Fidayanto, Hari Susanto, Agus Yohanan, Ririh Yudhastuti

Kesmas

Demam Berdarah Dengue (DBD) adalah penyakit berbasis vektor yang menjadi masalah kesehatan masyarakat di negara-negara tropis termasuk Indonesia. Penelitian ini bertujuan memprediksi kejadian DBD berdasarkan faktor iklim yang meliputi curah hujan, kelembaban, suhu udara dan lama penyinaran matahari serta model pengendalian. Desain penelitian adalah studi ekologi time series dengan data sekunder dari dinas kesehatan kota Surabaya meliputi kejadian DBD dan angka bebas jentik (ABJ) serta data iklim curah hujan, kelembaban, suhu udara dan lama penyinaran matahari yang didapatkan dari Badan Meteorologi dan Geofisika Badan (BMKG) stasiun perak Surabaya. Penelitian tersebut menemukan kelembaban berkorelasi dengan angka bebas jentik, tetapi ABJ tidak …

Inverted Sequence Identification In Diploid Genomic Scaffold Assembly Via Weighted Max-Cut Reduction, Paul Mark Bodily

Theses and Dissertations

Virtually all genome assemblers to date are designed for use with data from haploid or homozygous diploid genomes. Their use on heterozygous genomic datasets generally results in highly-fragmented, error-prone assemblies, owing to the violation of assumptions during both the contigging and scaffolding phases. Of the two phases, scaffolding is more particularly impacted and algorithms to facilitate the scaffolding of heterozygous data are lacking. We present a stand-alone scaffolding algorithm, ScaffoldScaffolder, designed specifically for scaffolding diploid genomes. A fundamental step in the scaffolding phase is the assignment of sequence orientations to contigs within scaffolds. Deciding such an assignment in the presence …

Beyond Jee: Finding Publication Venues To Get Your Message To The ‘Right’ Audience, Amy S. Van Epps

Libraries Faculty and Staff Scholarship and Research

Very few publications exist outlining the different publishing opportunities within engineering education as a discipline. Most researchers think immediately of the Journal of Engineering Education (JEE), and as the primary publication associated with the American Society for Engineering Education it is a logical first thought.

Questions arise with new graduate students and young faculty who are trying to learn the scope of engineering education as a research discipline and need to identify possible publication venues. A broad list of publications has been generated and is maintained by the ASEE Student Division in cooperation with the Center for Engineering Learning and …

Impaired Expression Of Protein Phosphatase 2a Subunits Enhances Metastatic Potential Of Human Prostate Cancer Cells Through Activation Of Akt Pathway., P Pandey, Parthasarathy Seshacharyulu, Srustidhar Das, Satyanarayana Rachagani, Moorthy P. Ponnusamy, Y Yan, Sonny L. Johansson, K Datta, Ming-Fong Lin, Surinder K. Batra

Journal Articles: Biochemistry & Molecular Biology

BACKGROUND: Protein phosphatase 2A (PP2A) is a dephosphorylating enzyme, loss of which can contribute to prostate cancer (PCa) pathogenesis. The aim of this study was to analyse the transcriptional and translational expression patterns of individual subunits of the PP2A holoenzyme during PCa progression.

METHODS: Immunohistochemistry (IHC), western blot, and real-time PCR was performed on androgen-dependent (AD) and androgen-independent (AI) PCa cells, and benign and malignant prostate tissues for all the three PP2A (scaffold, regulatory, and catalytic) subunits. Mechanistic and functional studies were performed using various biochemical and cellular techniques.

RESULTS: Through immunohistochemical analysis we observed significantly reduced levels of PP2A-A …

Conspicuous Consumption And Sedentary Living : Is This Our Legacy To Our Children?, Ritu Lakhtakia

Sultan Qaboos University Medical Journal

No abstract provided.

Mitochondrial Oxygen Consumption By The Foreskin And Its Fibroblast-Rich Culture, Fatma Al-Jasmi, Thachillath Pramathan, Adnan Sahari, Bahjat, Harvey S. Penefsky, Abdul-Kader Souid

Sultan Qaboos University Medical Journal

Objectives: This study investigated the feasibility of using a phosphorescence oxygen analyser to measure cellular respiration (mitochondrial O2 consumption) in foreskin samples and their fibroblast-rich cultures.Methods: Foreskin specimens from normal infants were collected immediately after circumcision and processed for measuring cellular respiration and for culture. Cellular mitochondrial O2 consumption was determined as a function of time from the phosphorescence decay of the Pd (II) meso-tetra-(4-sulfonatophenyl)-tetrabenzoporphyrin. Results: In sealed vials containing a foreskin specimen and glucose, O2 concentration decreased linearly with time, confirming the zero-order kinetics of O2 consumption by cytochrome oxidase. Cyanide inhibited O2 consumption, confirming that the oxidation occurred …

Re: Lipoprotein(A) And Syntax Score Association With Severity Of Coronary Artery Atherosclerosis In North India, Khawla H. Al-Musalh, Devaki R. Nair

Sultan Qaboos University Medical Journal

No abstract provided.

Stability And Change In Women's Personality Across The Life Course, Carly D. Lebaron

Theses and Dissertations

The current study sought to examine change and stability of personality in a sample of women over the course of 35 years. Existing research is mixed regarding whether or not personality changes over time or whether it remains stable. Using a sample of 187 women tracked over four time points (approximately 10 years between each time point), change and stability in openness to experience, extraversion, and neuroticism was tested using a stacked multilevel growth curve analysis. Four life course events (transition to parenthood, change in marital status, wife entering or leaving the workforce, and husband retiring) were added as predictors …

The Eastern Echo, June 25, 2013, Eastern Michigan University

EMU Student Newspaper: The Normal News & The Eastern Echo

No abstract provided.

Introducing A Rigid Loop Structure From Deer Into Mouse Prion Protein Increases Its Propensity For Misfolding In Vitro, Leah Kyle, Theodore R. John, Hermann M. Schätzl, Randolph V. Lewis

Biology Faculty Publications

Prion diseases are fatal neurodegenerative disorders characterized by misfolding of the cellular prion protein (PrPc) into the disease-associated isoform (PrPSc) that has increased β-sheet content and partial resistance to proteolytic digestion. Prion diseases from different mammalian species have varying propensities for transmission upon exposure of an uninfected host to the infectious agent. Chronic Wasting Disease (CWD) is a highly transmissible prion disease that affects free ranging and farmed populations of cervids including deer, elk and moose, as well as other mammals in experimental settings. The molecular mechanisms allowing CWD to maintain comparatively high transmission rates have not been determined. Previous …

Effectiveness Of Visual Aids On Preventive Dental Goals, Kristin Hodgson

Theses and Dissertations

Purpose: To assess a caregiver’s oral health attitudes, habits, and behaviors pre and post intervention, and to determine whether a particular delivery-style (verbal-only or with visual supplementation) of a motivational interviewing session is more effective in improving oral health behaviors as well as improving success of a chosen preventive goal. Methods: N=140 caregivers of pediatric dental patients were given questionnaires to assess readiness to change and current preventive oral health behaviors. Oral health education was communicated in a MI style (verbal-only or with visual supplementation). One preventive oral health goal was selected to focus on. The home preventive behavior survey …

Cannabinoids Delta-9-Tetrahydrocannabinol (Thc) And Cp55,940 Ablate Specific Chemokine And Cytokine Inflammatory Response In Bv-2 Mouse Microglial Cells Activated With Hiv-1 Pro-Inflammatory Protein Tat, Rebecca Maddux

Theses and Dissertations

Despite the widespread use of Highly Active Anti-retroviral Therapy (HAART) to combat Human Immunodeficiency Virus (HIV), the causative agent of acquired immunodeficiency syndrome (AIDS), HIV-Associated Neurocognitive Disorders (HANDs) still remain a dire issue. HIV can enter the brain through infected monocytes and infect microglia, the resident macrophages within that compartment. Due to its pro-inflammatory properties, HIV regulatory protein Tat (Transactivating protein) may play a role in the progression of neurocognitive disorders. The aim of this project was to determine whether the select cannabinoids THC and CP55,940 could ablate the inflammatory response on BV-2 mouse microglia cells caused by Tat. Within …

Designing A Valid Randomized Pragmatic Primary Care Implementation Trial: The My Own Health Report (Mohr) Project, Kurt C. Stange

Faculty Scholarship

Background: There is a pressing need for greater attention to patient-centered health behavior and psychosocial issues in primary care, and for practical tools, study designs and results of clinical and policy relevance. Our goal is to design a scientifically rigorous and valid pragmatic trial to test whether primary care practices can systematically implement the collection of patient-reported information and provide patients needed advice, goal setting, and counseling in response.Methods: This manuscript reports on the iterative design of the My Own Health Report (MOHR) study, a cluster randomized delayed intervention trial. Nine pairs of diverse primary care practices will be randomized …

Creative Actualization: A Meliorist Theory Of Values, Nate Jackson

Education and Culture

Hugh P. McDonald, Creative Actualization: A Meliorist Theory of Values. New York: Rodopi, 2011. + pages. ISBN 978-90-420-3253-8. $119.00 (hbk.)

Pragmatism And Community Inquiry: A Case Study Of Community-Based Learning, Bertram C. Bruce, Naomi Bloch

Education and Culture

This paper develops a philosophical basis for the concept of community inquiry. Community inquiry derives from pragmatist theory as articulated by Dewey, Peirce, Addams, and others. Following Brendel, we discuss pragmatism in terms of its emphasis on the practical dimensions of inquiry, the pluralistic nature of the tools that are used to study phenomena, the participatory role of individuals with different perspectives, and the provisional nature of inquiry. We then apply this framework in a case study of community inquiry in an urban agriculture project. The example shows how learning occurs both within and beyond the school, and how education …

Soft Null Hypotheses: A Case Study Of Image Enhancement Detection In Brain Lesions, Haochang Shou, Russell T. Shinohara, Han Liu, Daniel Reich, Ciprian Crainiceanu

Johns Hopkins University, Dept. of Biostatistics Working Papers

This work is motivated by a study of a population of multiple sclerosis (MS) patients using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) to identify active brain lesions. At each visit, a contrast agent is administered intravenously to a subject and a series of images is acquired to reveal the location and activity of MS lesions within the brain. Our goal is to identify and quantify lesion enhancement location at the subject level and lesion enhancement patterns at the population level. With this example, we aim to address the difficult problem of transforming a qualitative scientific null hypothesis, such as "this …