Digital Commons Network^™

Kandiyohi And Renville County Public Health - Health Data Compilation, Kelly Asche, Jordan Wente

Center for Small Towns

This project worked with Kandiyohi and Renville County Public Health to compile a comprehensive health narrative of the region. The narrative explored issues related to various health factors in the region, including demographic and economic factors. The final product was used to develop a list of priorities for health issues and initiatives.

Isso Weekly Newsletter, August 16, 2013, University Of Northern Iowa. International Students And Scholars Office.

ISSO Weekly Newsletter

Inside This Issue:

-- ISSO Office Has Moved
-- Welcome New Students!
-- Welcome Reception for New and Returning International Students
-- P.E.O. International Peace Scholarship Fund
-- University Mills Student Housing
-- Furnished Room for Rent
-- Car for Sale
-- ISSO Office Hours
-- Reminder to like our Facebook page
-- ISSO - Enhancing International Experiences

Nerve Growth Factor Receptor Trka, A New Receptor In Insulin Signaling Pathway In Pc12 Cells, Thangiah Geetha, Shraddha D. Rege, Salome E. Mathews, Susan O. Meakin, Morris F. White, Jeganathan Ramesh Babu

Paediatrics Publications

Background: TrkA is a transmembrane receptor tyrosine kinase for nerve growth factor. Results: TrkA forms a molecular complex with insulin receptor and IRS-1 to induce Akt and Erk5 phosphorylation. Conclusion: The NGF-TrkA receptor influences insulin signaling. Significance: The TrkA receptor is involved in insulin signaling, and NGF may regulate neuronal glucose uptake as neurons are insulin-insensitive. © 2013 by The American Society for Biochemistry and Molecular Biology, Inc.

Allostatic Load Amplifies The Effect Of Blood Lead Levels On Elevated Blood Pressure Among Middle-Aged U.S. Adults: A Cross-Sectional Study, Ami R. Zota, Edmond R. Shenassa, Rachel Morello-Frosch

Environmental and Occupational Health Faculty Publications

Background

Scientists and regulators have sought to understand whether and how physiologic dysregulation due to chronic stress exposure may enhance vulnerability to the adverse health effects of toxicant exposures. We conducted a cross-sectional study to determine whether allostatic load (AL), a composite measure of physiologic response to chronic exposure to stress, amplifies the effect of lead exposure on blood pressure among middle-aged adults.

Methods

We analyzed associations between blood lead levels and blood pressure in a nationally representative sample of 8,194 U.S. adults (aged 40-65 years) participating in the National Health and Nutritional Examination Survey, 1999--2008. Outcomes were elevated systolic …

Life Histories In Kizimkazi Dimbani, Zabzibar, Stephen B. Backman, Dr. David P. Crandall, Gary Burgess

Journal of Undergraduate Research

Kizimkazi Dimbani is a village of just over 1500 people on the southern end of the island of Zanzibar, which is about 50 miles off of the coast of Tanzania. In the fall of 1998 I went to Zanzibar with a group of seven BYU students under the International Study Programs Office in the Kennedy Center. The group performed a variety of research projects including topics focusing on health, conservation biology, village economics, education, and anthropology. My project was based on a study of the relationship between the kinship and political systems of the village. Through our research we were …

Non-Equilibrium Molecular Dynamics Study Of An Ion Channel With Aqueous Nacl: A Slab Geometry Approach, Nathan B. Holladay, David D. Busath

Journal of Undergraduate Research

An ion channel is a tunnel that allows ions to cross a barrier. Ion channels are common components of cellular membranes, helping to regulate ionic concentrations in different areas inside or outside cells. Electrical and/or concentration differences between one side of a membrane and the other often drive the net flow of ions in one direction or the other across the membrane. Theoretical biophysicists have used computer-based molecular dynamics simulations for years now to study the behavior of ions within ion channels under equilibrium conditions. Before our study, however, few or no studies had been done in which molecular dynamics …

Mutagenesis Of The Voltage-Gated Na+ Channel: S4 Charge Interaction With U-Conotoxin, David Allan Edwards, R. Paul Evans

Journal of Undergraduate Research

Within the membrane of excitable cells like those of nerve and muscle tissue, lie proteins called ion channels, which control the passage of ions in and out of the cell. The flow of ions stimulates the action of the cell, which ultimately leads to contraction of muscle tissue in the case of muscle cells, and sensation in the case of nerve cells. Seizures and pain sensation are extreme results of the action of these cells. To control pain, for example, we may use anesthetics that directly interact with ion channels and prevent the flow of ions across the cell membrane. …

The Alestle - Vol. 66 No. 1 - 08/16/2013, Southern Illinois University Edwardsville

The Alestle

Vol. 66 No. 1

Controlling Surface Chemistry On The Microscopic And Nanoscopic Scale Through Photopatterned Self-Assembled Monolayers, Matthew J. Hynes

All Theses and Dissertations (ETDs)

ABSTRACT OF DISSERTATION

Controlling Surface Chemistry on the Microscopic and Nanoscopic Scale through Photopatterned Self-Assembled Monolayers

by

Matthew J. Hynes

Doctor of Philosophy in Chemistry

Washington University in St. Louis, 2013

Professor Joshua A. Maurer, Chair

The development of new patterning strategies for self-assembled monolayers: SAMs) using photolithography described here allows for the production of highly functional substrates for biological applications. Photolithography methods have been developed that utilize either high or low irradiation doses of 325 nm ultraviolet light. Utilizing high power led to the development of photo-induced monolayer desorption in which patterns were generated by thermally ablating glycol-terminated thiol …

Modeling The Distribution Of Bobcats And Areas Of Reintroduction For Fisher In The Southern Washington Cascades, Shiloh Michael Halsey

Dissertations and Theses

The fisher (Martes pennanti) is a medium sized member of the mustelid family that once roamed the forests of Washington and whose historic range in the western United States once spread throughout the northern Rocky Mountains, the Cascade and Coast Ranges, and the Sierra Nevada (Carroll, Zielinski, and Noss 1999; Powell 1993, Spencer et al. 2011). Due to pressures from trapping and habitat fragmentation, the abundance of the species in the western United States has decreased dramatically and is thought to be limited to several small, isolated populations. In 2008, fishers were reintroduced to the Olympic Peninsula; however, bobcat (Lynx …

Jackson, Miss. Senior Visits Spain, Learns Language, Culture, Elaine Pugh

University of Mississippi News

No abstract provided.

Blowing Smoke: Harry Anslinger And The Marijuana Tax Act Of 1937, Michael Holifield

Student Theses and Dissertations

The issue of medical marijuana is a highly political issue within today's media coverage. At the core of the debate, is the nature of state's rights issues versus federal law supremacy. But most people don't know there was a time when medical marijuana was legal and openly used by pharmacists and doctors to treat various medical conditions. This documentary will explore the medical marijuana debate from a historical perspective of how the Federal Bureau of Narcotics changed the laws and public perception of a once widely used medical treatment during the 1930s. By examining communications theories including propaganda, framing theory, …

Dietary Modulation Of The Dynamics Between Leukocyte Inflammation, Cholesterol Flux, And Hdl Function In Metabolic Syndrome, Catherine Andersen

Doctoral Dissertations

Archival abstract submitted

Amyloid Β-Peptide (1–42)-Induced Oxidative Stress In Alzheimer Disease: Importance In Disease Pathogenesis And Progression, D. Allan Butterfield, Aaron M. Swomley, Rukhsana Sultana

Chemistry Faculty Publications

Significance: Alzheimer disease (AD) is an age-related neurodegenerative disease. AD is characterized by progressive cognitive impairment. One of the main histopathological hallmarks of AD brain is the presence of senile plaques (SPs) and another is elevated oxidative stress. The main component of SPs is amyloid beta-peptide (Aβ) that is derived from the proteolytic cleavage of amyloid precursor protein.

Recent Advances: Recent studies are consistent with the notion that methionine present at 35 position of Aβ is critical to Aβ-induced oxidative stress and neurotoxicity. Further, we also discuss the signatures of oxidatively modified brain proteins, identified using redox proteomics approaches, during …

Transfer Of Hiv From Fdc To Macrophages, Michael Fuller, Dr. Gregory Burton

Journal of Undergraduate Research

Over the last semester, I have been engaged in studying the ability of macrophages to pick up HIV from follicular dendritic cells (FDC) in the follicles of the lymph nodes. Research by Dr. Gregory F. Burton of Brigham Young University has shown that HIV virions held on the dendrite processes of follicular dendritic cells in immune complex form are still infectious, and can infect T cells. Research by Dr. Suzanne Gartner at Johns Hopkins University has shown homology between HIV isolated from the brain to HIV in the lymph nodes. Tying these data together, I hypothesized that macrophages are able …

Ion Channel Permeation: Kinetic Modeling Of Ion/Side-Chain Electrostatic Interactions In Native And Fluorinated Gramicidin Channels, Adam S. Frost, David D. Busath

Journal of Undergraduate Research

Gramicidin A is a 15-amino acid peptide produced by several strains of the bacteria Bacillus brevis. The primary sequence of gramicidin A is HCO-L-Val-Gly-L-Ala-D-Leu-L-Ala-D-Val-LVal- D-Val-L-Trp-D-Leu-L-Trp-D-Leu-L-Trp-D-Leu-L-Trp-NHCH2CH2OH. The side-chains alternate chirality, with the odd-numbered residues having the usual L-chirality and the evennumbered residues having D-chirality. The alternating chirality of the side-chains forces them to project away from the lumen of the helix, yielding a tight wind with a central hole formed by the space within the helix. The secondary structure of gramicidin is a single-stranded, left-handed, b6.5-helix that dimerizes head-to-head (N-terminus to N-terminus) in lipid bilayer membranes to form a monovalent, cation-selective …

Creating A Gene Deletion In Scherichia Coli, Brian J. Beames, Dr. William R. Mccleary

Journal of Undergraduate Research

Two component systems are an integral part of a bacterial cell. They consist of a histidine kinase and a response regulator. The histidine kinase is a receptor protein that signals from the outside of the cell to the inside. Once a ligand binds to the histidine kinase, it autophosphorylates on the inside of the cell and activates the response regulator by phosphorylating it. Once the response regulator is activated, it can then phosphorylate another protein of the cell and that protein can carry out its function. An example of a two component system is the Pho system. PhoB is a …

Life Histories In Kizimkazi Dimbani, Zabzibar, Stephen B. Backman, Dr. David P. Crandall, Dr. Gary Burgess

Journal of Undergraduate Research

Kizimkazi Dimbani is a village of just over 1500 people on the southern end of the island of Zanzibar, which is about 50 miles off of the coast of Tanzania. In the fall of 1998 I went to Zanzibar with a group of seven BYU students under the International Study Programs Office in the Kennedy Center. The group performed a variety of research projects including topics focusing on health, conservation biology, village economics, education, and anthropology. My project was based on a study of the relationship between the kinship and political systems of the village. Through our research we were …

Creation Of An Artificial Microbial Consortium, Sam Augustine, Dr. Alan Harker

Journal of Undergraduate Research

Ecology is the study of the interactions of living organisms with each other and their environment. In microbiology there has been relatively little done in this field compared to the macro-biological world. In traditional macro-scale ecology an environment is clearly delineated by physical boundaries, access to resources and competition.

Titanium-6aluminum-4vanadium For Functionally Graded Orthopedic Implant Applications, Kyle D. Crosby

Doctoral Dissertations

Rising costs of health care are attributed to an increasing number of medical procedures with great complexity and costly instrumentation. Novel materials and devices must be developed to reduce the time, economic cost, and physical pain associated with invasive orthopedic surgery. As well the lifetime of components must be extended to meet the needs of a population with an increasing life expectancy. To prolong the lifetime of an implant device, components should closely mimic the naturally occurring biological structure they are replacing in terms of both mechanical and biological function in order to assimilate undetected in the human body. Studies …

Meeting Minutes, Wku Graduate Council

Graduate School

Meeting minutes.

Age Differences In Women’S Anger Experience And Expression, A. Antonio González-Prendes, Nancy Praill, Poco Kernsmith

Social Work Faculty Publications

Research on women’s anger is relative scarce. In this study the authors examined differences in anger experience and expression in women across three distinct age groups: 18-30, 31-49, and 50 and above. The authors used the State-Trait Anger Expression Inventory-2 (STAXI-2) to survey a sample of 239 women in the United States and Canada. The groups were established according to hypothesized transitional life stages of changing responsibilities and expectations. A MANCOVA was used to test the effect of age and covariates of education, employment, relationship status, and country of residence on participants’ experience and expression of anger. The authors discuss …

Eng 3702-001: American Literature: Mid-19th Century To 1900, John Allison

Fall 2013

No abstract provided.

Nine Tenure-Track Professors Join Macalester, Macalester College

College Press Releases

No abstract provided.

2013-2014, Collin College

Course Catalogs

Contains information on courses and class descriptions as well as campus resources at Collin College.

Eng 2009g-001: Literature & Human Values: Love, Hate, & Obsession, Charlotte Pence

Fall 2013

No abstract provided.

The Possible Negative Consequences Of Underground Dam And Reservoir Construction And Operation In Coastal Karst Areas: An Example Of The Hydro-Electric Power Plant (Hepp) Ombla Near Dubrovnik (Croatia), T. Roje-Bonacci, O. Bonacci

KIP Articles

The Ombla Spring represents a typical abundant coastal karst spring located in the vicinity of the town of Dubrovnik (Croatia). Its outlet is at an altitude of 2.5 m above sea level (m a.s.l.) and the water from it immediately flows into the Adriatic Sea. The minimum and maximum measured discharges are 3.96 m3 s−1 and 117 m3 s−1, respectively. The Trebišnjica River traverses through its catchment. The mean annual discharge, after the canalization of over 60 km of its watercourse with spray concrete (in the time span 1981–2011), is 24.05 m3 s−1. Before massive civil engineering work which took …

The Possible Negative Consequences Of Underground Dam And Reservoir Construction And Operation In Coastal Karst Areas: An Example Of The Hydro-Electric Power Plant (Hepp) Ombla Near Dubrovnik (Croatia), T. Roje-Bonacci, O. Bonacci

KIP Articles

Abstract. The Ombla Spring represents a typical abundant coastal karst spring located in the vicinity of the town of Dubrovnik (Croatia). Its outlet is at an altitude of 2.5 m above sea level (m a.s.l.) and the water from it immediately flows into the Adriatic Sea. The minimum and maximum measured discharges are 3.96 m3 s−1 and 117 m3 s−1, respectively. The Trebišnjica River traverses through its catchment. The mean annual discharge, after the canalization of over 60 km of its watercourse with spray concrete (in the time span 1981–2011), is 24.05 m3 s−1. Before massive civil engineering work which …

Intracellular Reprogramming Of Expression, Glycosylation, And Function Of A Plant-Derived Antiviral Therapeutic Monoclonal Antibody., Jeong-Hwan Lee, Da-Young Park, Kyung-Jin Lee, Young-Kwan Kim, Yang-Kang So, Jae-Sung Ryu, Seung-Han Oh, Yeon-Soo Han, Kinarm Ko, Young-Kug Choo, Sung-Joo Park, Robert Brodzik, Kyoung-Ki Lee, Doo-Byoung Oh, Kyung-A Hwang, Hilary Koprowski, Yong Seong Lee, Kisung Ko

Department of Cancer Biology Faculty Papers

Plant genetic engineering, which has led to the production of plant-derived monoclonal antibodies (mAb(P)s), provides a safe and economically effective alternative to conventional antibody expression methods. In this study, the expression levels and biological properties of the anti-rabies virus mAb(P) SO57 with or without an endoplasmic reticulum (ER)-retention peptide signal (Lys-Asp-Glu-Leu; KDEL) in transgenic tobacco plants (Nicotiana tabacum) were analyzed. The expression levels of mAb(P) SO57 with KDEL (mAb(P)K) were significantly higher than those of mAb(P) SO57 without KDEL (mAb(P)) regardless of the transcription level. The Fc domains of both purified mAb(P) and mAb(P)K and hybridoma-derived mAb (mAb(H)) had similar …

2013-August-15-National Pre-Med Rankings, University Marketing And Communication, East Tennessee State University

ETSU News

No abstract provided.