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2013

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Zeb1 Imposes A Temporary Stage-Dependent Inhibition Of Muscle Gene Expression And Differentiation Via Ctbp-Mediated Transcriptional Repression, Laura Siles, Ester Sanchez-Tillo, Jong-Won Lim, Douglas S. Darling, Kristen L. Kroll, Antonio Postigo Jan 2013

Zeb1 Imposes A Temporary Stage-Dependent Inhibition Of Muscle Gene Expression And Differentiation Via Ctbp-Mediated Transcriptional Repression, Laura Siles, Ester Sanchez-Tillo, Jong-Won Lim, Douglas S. Darling, Kristen L. Kroll, Antonio Postigo

Open Access Publications

No abstract provided.


Control The Host Cell Cycle: Viral Regulation Of The Anaphase-Promoting Complex, Anthony R. Fehr, Dong Yu Jan 2013

Control The Host Cell Cycle: Viral Regulation Of The Anaphase-Promoting Complex, Anthony R. Fehr, Dong Yu

Open Access Publications

No abstract provided.


A Role For Ifit2 In Restricting West Nile Virus Infection In The Brain, Hyelim Cho, Bimmi Shrestha, Ganes C. Sen, Michael S. Diamond Jan 2013

A Role For Ifit2 In Restricting West Nile Virus Infection In The Brain, Hyelim Cho, Bimmi Shrestha, Ganes C. Sen, Michael S. Diamond

Open Access Publications

No abstract provided.


Histone Methylation Keeps The Brakes On Autophagy, Patrick L. Collins, Eugene M. Oltz Jan 2013

Histone Methylation Keeps The Brakes On Autophagy, Patrick L. Collins, Eugene M. Oltz

Open Access Publications

No abstract provided.


Talin1 And Rap1 Are Critical For Osteoclast Function, Wei Zou, Takashi Izawa, Tingting Zhu, Jean Chappel, Karel Otero, Susan J. Monkley, David R. Critchley, Brian G. Petrich, Alexei Morozov, Mark H. Ginsberg, Steven L. Teitelbaum Jan 2013

Talin1 And Rap1 Are Critical For Osteoclast Function, Wei Zou, Takashi Izawa, Tingting Zhu, Jean Chappel, Karel Otero, Susan J. Monkley, David R. Critchley, Brian G. Petrich, Alexei Morozov, Mark H. Ginsberg, Steven L. Teitelbaum

Open Access Publications

No abstract provided.


Hepatitis C Virus Infection Upregulates Cd55 Expression On The Hepatocyte Surface And Promotes Association With Virus Particles, Budhaditya Mazumdar, Hangeun Kim, Keith Meyer, Sandip K. Bose, Adrian M. Di Bisceglie, Ratna B. Ray, Michael S. Diamond, John P. Atkinson, Ranjit Ray Jan 2013

Hepatitis C Virus Infection Upregulates Cd55 Expression On The Hepatocyte Surface And Promotes Association With Virus Particles, Budhaditya Mazumdar, Hangeun Kim, Keith Meyer, Sandip K. Bose, Adrian M. Di Bisceglie, Ratna B. Ray, Michael S. Diamond, John P. Atkinson, Ranjit Ray

Open Access Publications

No abstract provided.


Lamin A/C Depletion Enhances Dna Damage-Induced Stalled Replication Fork Arrest, Clayton R. Hunt, Raj K. Pandita, Rakesh Kumar, Nobuo Horikoshi, Simon N. Powell, Arun Gupta, Shruti Pandita, Qin Yang, Tej K. Pandita, Et Al Jan 2013

Lamin A/C Depletion Enhances Dna Damage-Induced Stalled Replication Fork Arrest, Clayton R. Hunt, Raj K. Pandita, Rakesh Kumar, Nobuo Horikoshi, Simon N. Powell, Arun Gupta, Shruti Pandita, Qin Yang, Tej K. Pandita, Et Al

Open Access Publications

No abstract provided.


Ip Injury And The Institutions Of Patent Law, Paul Gugliuzza Jan 2013

Ip Injury And The Institutions Of Patent Law, Paul Gugliuzza

Faculty Scholarship

This paper reviews Creation Without Restraint: Promoting Liberty and Rivalry in Innovation, the pathbreaking book by Christina Bohannan and Herbert Hovenkamp (Oxford Univ. Press 2012). The Review begins by summarizing the book’s descriptive insights and analyzing one of its important normative proposals: the adoption of an IP injury requirement. This requirement would demand that infringement plaintiffs prove -- before obtaining damages or an injunction -- an injury to the incentive to innovate. After explaining how this requirement is easy to justify under governing law and is largely consistent with recent Supreme Court decisions in the field of patent law, the …


Against Endowment Theory: Experimental Economics And Legal Scholarship, Greg Klass, Kathryn Zeiler Jan 2013

Against Endowment Theory: Experimental Economics And Legal Scholarship, Greg Klass, Kathryn Zeiler

Faculty Scholarship

Endowment theory holds the mere ownership of a thing causes people to assign greater value to it than they otherwise would. The theory entered legal scholarship in the early 1990s and quickly eclipsed other accounts of how ownership affects valuation. Today, appeals to a generic “endowment effect” can be found throughout the legal literature. More recent experimental results, however, suggest that the empirical evidence for endowment theory is weak at best. When the procedures used in laboratory experiments are altered to rule out alternative explanations, the “endowment effect” disappears. This and other recent evidence suggest that mere ownership does not …


What Is Parenthood?: Contemporary Debates About The Family Introduction, Linda C. Mcclain, Daniel Cere Jan 2013

What Is Parenthood?: Contemporary Debates About The Family Introduction, Linda C. Mcclain, Daniel Cere

Faculty Scholarship

Extraordinary changes in patterns of family life – and family law – have dramatically altered the boundaries of parenthood and opened up numerous questions about debates. What is parenthood and why does it matter? How should society define, regulate, and support it? Despite this uncertainty, the intense focus on the definition and future of marriage diverts attention from parenthood. Demographic reports suggesting a shift away from marriage and toward alternative family forms also keep marriage in constant public view, obscuring the fact that disagreements about marriage are often grounded in deeper, conflicting convictions about parenthood. This book (as the posted …


"Simple" Takes On The Supreme Court, Robert L. Tsai Jan 2013

"Simple" Takes On The Supreme Court, Robert L. Tsai

Faculty Scholarship

This essay assesses black literature as a medium for working out popular understandings of America’s Constitution and laws. Starting in the 1940s, Langston Hughes’s fictional character, Jesse B. Semple, began appearing in the prominent black newspaper, the Chicago Defender. The figure affectionately known as “Simple” was undereducated, unsophisticated, and plain spoken - certainly to a fault according to prevailing standards of civility, race relations, and professional attainment. Butthese very traits, along with a gritty experience under Jim Crow, made him not only a sympathetic figure but also an armchair legal theorist. In a series of barroom conversations, Simple ably critiqued …


Repetitive Concussive Traumatic Brain Injury Interacts With Post-Injury Foot Shock Stress To Worsen Social And Depression-Like Behavior In Mice, Kristen C. Klemenhagen, Scott P. O'Brien, David L. Brody Jan 2013

Repetitive Concussive Traumatic Brain Injury Interacts With Post-Injury Foot Shock Stress To Worsen Social And Depression-Like Behavior In Mice, Kristen C. Klemenhagen, Scott P. O'Brien, David L. Brody

Open Access Publications

No abstract provided.


Role Of Choline Deficiency In The Fatty Liver Phenotype Of Mice Fed A Low Protein, Very Low Carbohydrate Ketogenic Diet, Rebecca C. Schugar, Xiaojing Huang, Ashley R. Moll, Elizabeth M. Brunt, Peter A. Crawford Jan 2013

Role Of Choline Deficiency In The Fatty Liver Phenotype Of Mice Fed A Low Protein, Very Low Carbohydrate Ketogenic Diet, Rebecca C. Schugar, Xiaojing Huang, Ashley R. Moll, Elizabeth M. Brunt, Peter A. Crawford

Open Access Publications

No abstract provided.


Asparagine Repeats In Plasmodium Falciparum Proteins: Good For Nothing?, Vasant Muralidharan, Daniel E. Goldberg Jan 2013

Asparagine Repeats In Plasmodium Falciparum Proteins: Good For Nothing?, Vasant Muralidharan, Daniel E. Goldberg

Open Access Publications

No abstract provided.


The Expression And Localization Of N-Myc Downstream-Regulated Gene 1 In Human Trophoblasts, Xiao-Hua Shi, Jacob C. Larkin, Baosheng Chen, Yoel Sadovsky Jan 2013

The Expression And Localization Of N-Myc Downstream-Regulated Gene 1 In Human Trophoblasts, Xiao-Hua Shi, Jacob C. Larkin, Baosheng Chen, Yoel Sadovsky

Open Access Publications

No abstract provided.


Differentially Expressed Micrornas In Chondrocytes From Distinct Regions Of Developing Human Cartilage, Audrey Mcalinden, Nobish Varghese, Louisa Wirthlin, Li-Wei Chang Jan 2013

Differentially Expressed Micrornas In Chondrocytes From Distinct Regions Of Developing Human Cartilage, Audrey Mcalinden, Nobish Varghese, Louisa Wirthlin, Li-Wei Chang

Open Access Publications

No abstract provided.


Physiological Role Of The Interaction Between Carmil1 And Capping Protein, Marc Edwards, Yun Liang, Taekyung Kim, John A. Cooper Jan 2013

Physiological Role Of The Interaction Between Carmil1 And Capping Protein, Marc Edwards, Yun Liang, Taekyung Kim, John A. Cooper

Open Access Publications

No abstract provided.


Effects Of Diet On Resource Utilization By A Model Human Gut Microbiota Containing Bacteroides Cellulosilyticus Wh2, A Symbiont With An Extensive Glycobiome, Nathan P. Mcnulty, Meng Wu, Alison R. Erickson, Chongle Pan, Brian K. Erickson, Eric C. Martens, Nicholas A. Pudlo, Brian D. Muegge, Bernard Henrissat, Robert Hettich, Jeffrey I. Gordon Jan 2013

Effects Of Diet On Resource Utilization By A Model Human Gut Microbiota Containing Bacteroides Cellulosilyticus Wh2, A Symbiont With An Extensive Glycobiome, Nathan P. Mcnulty, Meng Wu, Alison R. Erickson, Chongle Pan, Brian K. Erickson, Eric C. Martens, Nicholas A. Pudlo, Brian D. Muegge, Bernard Henrissat, Robert Hettich, Jeffrey I. Gordon

Open Access Publications

No abstract provided.


Mechanistic Model Of Natural Killer Cell Proliferative Response To Il-15 Receptor Stimulation, Yun M. Zhao, Anthony R. French Jan 2013

Mechanistic Model Of Natural Killer Cell Proliferative Response To Il-15 Receptor Stimulation, Yun M. Zhao, Anthony R. French

Open Access Publications

No abstract provided.


Whole-Genome Draft Sequences Of 26 Enterohemorrhagic Escherichia Coli O157:H7 Strains, Phillip I. Tarr, Et Al Jan 2013

Whole-Genome Draft Sequences Of 26 Enterohemorrhagic Escherichia Coli O157:H7 Strains, Phillip I. Tarr, Et Al

Open Access Publications

No abstract provided.


Genome-Wide Association Of Body Fat Distribution In African Ancestry Populations Suggests New Loci, Mary K. Wojczynski, Ingrid B. Borecki, Et Al Jan 2013

Genome-Wide Association Of Body Fat Distribution In African Ancestry Populations Suggests New Loci, Mary K. Wojczynski, Ingrid B. Borecki, Et Al

Open Access Publications

No abstract provided.


An Association Between Peptidoglycan Synthesis And Organization Of The Streptococcus Pyogenes Exportal, Luis Alberto Vega, Gary C. Port, Michael G. Caparon Jan 2013

An Association Between Peptidoglycan Synthesis And Organization Of The Streptococcus Pyogenes Exportal, Luis Alberto Vega, Gary C. Port, Michael G. Caparon

Open Access Publications

No abstract provided.


A Mouse Model For Human Norovirus, Stefan Taube, Abimbola O. Kolawole, Marina Hohne, John E. Wilkinson, Scott A. Handley, Jeffrey W. Perry, Larissa B. Thackray, Ramesh Akkina, Christiane E. Wobus Jan 2013

A Mouse Model For Human Norovirus, Stefan Taube, Abimbola O. Kolawole, Marina Hohne, John E. Wilkinson, Scott A. Handley, Jeffrey W. Perry, Larissa B. Thackray, Ramesh Akkina, Christiane E. Wobus

Open Access Publications

No abstract provided.


Lymphatic Vasculature Mediates Macrophage Reverse Cholesterol Transport In Mice, Catherine Martel, Wenjun Li, Emmanuel Gautier, Daniel Kreisel, Gwendalyn J. Randolph, Brian Fulp, Andrew M. Platt, Marit Westerterp, Robert Bittman, Alan R. Tall, Shu-Hsia Chen, Michael J. Thomas, Melody A. Swartz, Mary G. Sorci-Thomas Jan 2013

Lymphatic Vasculature Mediates Macrophage Reverse Cholesterol Transport In Mice, Catherine Martel, Wenjun Li, Emmanuel Gautier, Daniel Kreisel, Gwendalyn J. Randolph, Brian Fulp, Andrew M. Platt, Marit Westerterp, Robert Bittman, Alan R. Tall, Shu-Hsia Chen, Michael J. Thomas, Melody A. Swartz, Mary G. Sorci-Thomas

Open Access Publications

No abstract provided.


Daptomycin-Resistant Enterococcus Faecalis Diverts The Antibiotic Molecule From The Division Septum And Remodels Cell Membrane Phospholipids, Truc T. Tran, Diana Panesso, Nagendra N. Mishra, Eugenia Mileykovskaya, Ziqianq Guan, Jose M. Munita, Jinnethe Reyes, Lorena Diaz, George M. Weinstock, Barbara E. Murray, Yousif Shamoo, William Dowhan, Arnold S. Bayer, Cesar A. Arias Jan 2013

Daptomycin-Resistant Enterococcus Faecalis Diverts The Antibiotic Molecule From The Division Septum And Remodels Cell Membrane Phospholipids, Truc T. Tran, Diana Panesso, Nagendra N. Mishra, Eugenia Mileykovskaya, Ziqianq Guan, Jose M. Munita, Jinnethe Reyes, Lorena Diaz, George M. Weinstock, Barbara E. Murray, Yousif Shamoo, William Dowhan, Arnold S. Bayer, Cesar A. Arias

Open Access Publications

No abstract provided.


Nucear Expression Of Snail Is An Independent Negative Prognostic Factor In Human Breast Cancer, S Muenst, S. Däster, E C. Obermann, R A. Droeser, W P. Weber, U Von Holzen, F Gao, C Viehl, D Oertli, S D. Soysal Jan 2013

Nucear Expression Of Snail Is An Independent Negative Prognostic Factor In Human Breast Cancer, S Muenst, S. Däster, E C. Obermann, R A. Droeser, W P. Weber, U Von Holzen, F Gao, C Viehl, D Oertli, S D. Soysal

Open Access Publications

No abstract provided.


Il-12p70–Producing Patient Dc Vaccine Elicits Tc1-Polarized Immunity, Beatriz M. Carreno, Michelle Becker-Hapak, Alexander Huang, Megan Chan, Amer Alyasiry, Wen-Rong Lie, Rebecca L. Aft, Lynn A. Cornelius, Kathryn M. Trinkaus, Gerald P. Linette Jan 2013

Il-12p70–Producing Patient Dc Vaccine Elicits Tc1-Polarized Immunity, Beatriz M. Carreno, Michelle Becker-Hapak, Alexander Huang, Megan Chan, Amer Alyasiry, Wen-Rong Lie, Rebecca L. Aft, Lynn A. Cornelius, Kathryn M. Trinkaus, Gerald P. Linette

Open Access Publications

No abstract provided.


Patent Variation: Discerning Diversity Among Patent Functions, Jessica Silbey Jan 2013

Patent Variation: Discerning Diversity Among Patent Functions, Jessica Silbey

Faculty Scholarship

This Article describes and analyzes qualitative interview data collected over a five-year period. The goal of the interviews was to explore the roles of intellectual property (“IP”) in IP rich fields. Interviews were with diverse actors in a wide-range of industries: film, book publishing, visual arts, internet commerce, biology, engineering, chemistry, computer science. The data described and analyzed in this Article focuses on the specific question about the diverse functioning of patents in the subset of interviewees who are scientists and engineers, their lawyers and business partners. The Article proceeds in two parts. Part I describes the empirical dimension of …


Diabetes Increases Mortality After Myocardial Infarction By Oxidizing Camkii, Di Lang, Igor R. Efimov, Min Luo, Xiaoqun Guan, Elizabeth D. Luczak, William Kutschke, Zhan Gao, Jinying Yang, Patric Glynn, Samuel Sossalla, Paari D. Swaminathan, Robert M. Weiss, Baoli Yang, Adam G. Rokita, Et Al. Jan 2013

Diabetes Increases Mortality After Myocardial Infarction By Oxidizing Camkii, Di Lang, Igor R. Efimov, Min Luo, Xiaoqun Guan, Elizabeth D. Luczak, William Kutschke, Zhan Gao, Jinying Yang, Patric Glynn, Samuel Sossalla, Paari D. Swaminathan, Robert M. Weiss, Baoli Yang, Adam G. Rokita, Et Al.

Open Access Publications

No abstract provided.


Efficiency Of First-Trimester Uterine Artery Doppler, A-Disintegrin And Metalloprotease 12, Pregnancy-Associated Plasma Protein A, And Maternal Characteristics In The Prediction Of Preeclampsia, Katherine R. Goetzinger, Yan Zhong, Alison G. Cahill, Linda Odibo, George A. Macones, Anthony O. Odibo Jan 2013

Efficiency Of First-Trimester Uterine Artery Doppler, A-Disintegrin And Metalloprotease 12, Pregnancy-Associated Plasma Protein A, And Maternal Characteristics In The Prediction Of Preeclampsia, Katherine R. Goetzinger, Yan Zhong, Alison G. Cahill, Linda Odibo, George A. Macones, Anthony O. Odibo

Open Access Publications

No abstract provided.