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2013

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Impact Of Physical Activity In The Prevention Of Colorectal Cancer, Sarah Ashley Barnes Jan 2013

Impact Of Physical Activity In The Prevention Of Colorectal Cancer, Sarah Ashley Barnes

Theses and Dissertations

This review evaluates the current understanding of research on the impact of physical activity in the prevention of colorectal cancer. Current biological mechanisms implicated in physical activity and colorectal cancer risk reduction are blood glucose regulation, insulin sensitivity, leptin and adiponectin profiles, inflammation as well as secreted protein acidic and rich in cysteine (SPARC), an exercise induced myokine. Recent literature indicates that 30-60 minutes of moderate to vigorous activity a day is effective against colorectal cancer development, and there is convincing evidence of aerobic exercise as differently beneficial in recruiting mechanisms identified as preventative against colorectal cancer. This article provides …

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Resveratrol Attenuates The Development Of Trans-Aortic Constriction (Tac) Induced Heart Failure In Mice, Prakash Kumar Gupta Jan 2013

Resveratrol Attenuates The Development Of Trans-Aortic Constriction (Tac) Induced Heart Failure In Mice, Prakash Kumar Gupta

Theses and Dissertations

Heart failure (HF) still remains the leading cause of morbidity and mortality and imposes severe global affliction and enormous cost on the healthcare system. Although current pharmacological therapies have shown to slow down the progression of HF, but seems to have reached their limits in improving overall patient prognosis. Thus, an immediate call for novel alternate therapies are needed which act independently as well as in conjunction with current treatment modality. Studies were performed in the well-established transverse aortic constriction (TAC) model of chronic pressure overload (PO) in mice. In the first series of studies, Male C57BL6 mice (26-28 g) …

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Linking Obesity To Colorectal Cancer: Recent Insights Into Plausible Biological Mechanisms, Catherine Guffey Jan 2013

Linking Obesity To Colorectal Cancer: Recent Insights Into Plausible Biological Mechanisms, Catherine Guffey

Theses and Dissertations

Obesity has emerged as a leading environmental risk factor for the development of CRC. However, the mechanisms underlying this relationship have not yet been fully explained. Recent literature has focused on 1) inflammatory processes, 2) adipokines, and 3) estrogen. Obesity-enhanced inflammation is largely orchestrated by increases in adipose tissue macrophages leading to the secretion of TNF-alpha, MCP-1, and IL-6, all of which are linked to CRC. Adiponectin is decreased with obesity and has been reported to be negatively associated with CRC, while leptin, which is increased, is positively associated with the disease. Estrogen has been shown to influence CRC, although …

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Examining The Direct And Interactive Effects Of Positive Coping On Depressive Symptomology In African American Women, Heather Andrea Eaddy Jan 2013

Examining The Direct And Interactive Effects Of Positive Coping On Depressive Symptomology In African American Women, Heather Andrea Eaddy

Theses and Dissertations

In the larger stress and coping literature, several studies have examined ethnic differences in stress experiences and coping behaviors (Plummer and Slane, 1996; Slavin et al., 1991; Brantley et al., 2002). However, these studies are often comparative in nature and fail to examine within group variation (Plummer & Slane, 1996; Slavin et al., 1991; Smith, 1985). Similarly, studies have also neglected to examine how African American women cope when confronted with certain stressors and the associated mental health outcomes. With this in mind, the goal of the current study is to close existing gaps by examining the relationship between routine …

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How Species Richness And Total Abundance Constrain The Distribution Of Abundance, Kenneth J. Locey, Ethan P. White Jan 2013

How Species Richness And Total Abundance Constrain The Distribution Of Abundance, Kenneth J. Locey, Ethan P. White

Biology Faculty Publications

The species abundance distribution (SAD) is one of the most intensively studied distributions in ecology and its hollow-curve shape is one of ecology’s most general patterns. We examine the SAD in the context of all possible forms having the same richness (S) and total abundance (N), i.e. the feasible set. We find that feasible sets are dominated by similarly-shaped hollow-curves, most of which are highly correlated with empirical SADs (most R2 values > 75%), revealing a strong influence of N and S on the form of the SAD and an a priori explanation for the ubiquitous hollow-curve. Empirical SADs are often …

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Life History, C. W. Fox, Frank J. Messina Jan 2013

Life History, C. W. Fox, Frank J. Messina

Biology Faculty Publications

No abstract provided.

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General Reproductive Properties In Pigs, İrfan Tur Jan 2013

General Reproductive Properties In Pigs, İrfan Tur

Turkish Journal of Veterinary & Animal Sciences

Pig breeding is usually undertaken for fat and meat production, but different sectors (cosmetics industry, pharmaceutical industry, medical sector, etc.) can also use pigs for alternate purposes. Pork is evaluated based on the status of an amended law regarding butchers' meat in Turkey. There have been 25 pig farms registered in Turkey since 7 July 2006 in the framework of compliance with the European Union. On average, a sow has 2.3 farrowings per year, producing 9.5 to 12.5 piglets per litter. It is important that high proportions of selected replacement gilts reach puberty at an early age in order to …

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Effect Of Oocyte Quality And Activation Protocols On Bovine Embryo Development Following Intracytoplasmic Sperm Injection, Ömer Korkmaz, Şükrü Küplülü, Yüksel Ağca, İbrahi̇m Mert Polat Jan 2013

Effect Of Oocyte Quality And Activation Protocols On Bovine Embryo Development Following Intracytoplasmic Sperm Injection, Ömer Korkmaz, Şükrü Küplülü, Yüksel Ağca, İbrahi̇m Mert Polat

Turkish Journal of Veterinary & Animal Sciences

The purpose of this study was to investigate the effects of oocyte quality and activation protocols on the in vitro developmental competence of bovine embryos after intracytoplasmic sperm injection (ICSI). Bovine oocytes were grouped as being of excellent, good, and poor quality. All of the oocytes were activated using a calcium ionophore only, ethanol only, and 6-dimethylaminopurine (6-DMAP) following calcium ionophore. For the excellent quality oocytes, cleavage rates after ICSI were 70% in the Ca ionophore + 6-DMAP activation group, 47% in the ethanol activation group, 41.82% in the Ca ionophore group, and 30% in the nontreated control group. Cleavage …

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The Effect Of Selenized Yeast Supplementation On Some Performance Parameters In Sheep, Bogumila Pilarczyk, Agnieszka Tomza-Marciniak, Zbigniew Dobrzanski, Malgorzata Szewczuk, Tomasz Stankiewicz, Dariusz Gaczarzewicz, Wlodzimierz Lachowski Jan 2013

The Effect Of Selenized Yeast Supplementation On Some Performance Parameters In Sheep, Bogumila Pilarczyk, Agnieszka Tomza-Marciniak, Zbigniew Dobrzanski, Malgorzata Szewczuk, Tomasz Stankiewicz, Dariusz Gaczarzewicz, Wlodzimierz Lachowski

Turkish Journal of Veterinary & Animal Sciences

The aim of this study was to determine the levels of serum selenium in coarse-haired Pomeranian sheep and to evaluate the effect of the oral supplementation of selenized yeast on selected performance parameters in such sheep. The sheep were divided into 2 groups, with 53 ewes forming the experimental group and 34 ewes forming the control group. The concentration of serum selenium in all 87 sheep from the 2 groups was analyzed. The sheep in the experimental group received selenized yeast for the 3 days before and 3 days after mating (1 g preparation/animal daily, with 1 g of preparation …

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Whole-Blood Thrombelastography Using Calcium Chloride Activation In Healthy Cats, Ramazan Çöl, Alicia Montgomery, Maria Cristina Iazbik, Ashley Defelice, Poulo Vilar Saavedra, Guillermo Couto Jan 2013

Whole-Blood Thrombelastography Using Calcium Chloride Activation In Healthy Cats, Ramazan Çöl, Alicia Montgomery, Maria Cristina Iazbik, Ashley Defelice, Poulo Vilar Saavedra, Guillermo Couto

Turkish Journal of Veterinary & Animal Sciences

Thrombelastography (TEG, Haemoscope Corp., Niles, IL, USA) allows for a global evaluation of the hemostatic system; while conventional coagulation tests typically evaluate only one part of the coagulation system, TEG simultaneously examines the interaction between platelets, clotting factors, the fibrinolytic system, and clot retraction mechanisms. Since its development, TEG has been widely employed in human clinical medicine and research, but has only recently gained popularity in veterinary medicine. The purpose of this study was to establish TEG reference ranges in healthy cats using the citrated native technique. In this study, 31 clinically healthy cats were evaluated. We sampled healthy adult …

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Embedding Student Research Publication Opportunities: Strategies For Widening Engagement With Undergraduate Research Journals, H Walkington, A Edwards-Jones, K Gresty Jan 2013

Embedding Student Research Publication Opportunities: Strategies For Widening Engagement With Undergraduate Research Journals, H Walkington, A Edwards-Jones, K Gresty

Professional Services

No abstract provided.

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Comparative Imaging Of The Vesicular Glands In New Zealand White Rabbits (Oryctolagus Cuniculus), Rosen Dimitrov, Kamelia Stamatova, Dimitar Kostov Jan 2013

Comparative Imaging Of The Vesicular Glands In New Zealand White Rabbits (Oryctolagus Cuniculus), Rosen Dimitrov, Kamelia Stamatova, Dimitar Kostov

Turkish Journal of Veterinary & Animal Sciences

This study investigated the morphological topographic features of the vesicular glands (gll. vesiculosae) in 10 sexually mature and clinically healthy male New Zealand White rabbits, aged 12 months, with body weights from 2.8 kg to 3.2 kg. The glands were observed by ultrasonography in 2 planes, transversal and sagittal. The approach was percutaneous transabdominal prepubic. The rabbit vesicular glands were visualized as a solid heterogeneous echoic finding. Using computed tomography, we scanned the pelvis in the transversal plane through the first sacral vertebra, at a cut thickness of 3 mm. The vesicular glands were visualized as transversally ovoid, homogeneous, and …

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Occurrence Of Anti-Toxoplasma Gondii And Neospora Caninum Antibodies In Camels (Camelus Dromedarius) In The Center Of Iran, Hossein Hamidinejat, Masoud Ghorbanpour, Aria Rasooli, Mohammad Nouri, Seyedhossein Hekmatimoghaddam, Mohammad Mehdi Namavari, Mehdi Pourmehdi-Borojeni, Alireza Sazmand Jan 2013

Occurrence Of Anti-Toxoplasma Gondii And Neospora Caninum Antibodies In Camels (Camelus Dromedarius) In The Center Of Iran, Hossein Hamidinejat, Masoud Ghorbanpour, Aria Rasooli, Mohammad Nouri, Seyedhossein Hekmatimoghaddam, Mohammad Mehdi Namavari, Mehdi Pourmehdi-Borojeni, Alireza Sazmand

Turkish Journal of Veterinary & Animal Sciences

During the period from December 2008 to September 2009, we examined 254 serum samples (164 in hot-dry weather and 90 in cold-dry weather) from dromedary camels distributed all over Yazd Province, in the center of Iran. IgG antibodies were assayed by the modified agglutination test (MAT) and Neospora agglutination test (NAT) using whole tachyzoites of Toxoplasma gondii and Neospora caninum, incorporating 2-mercaptoethanol, for T. gondii and N. caninum, respectively. Anti-T. gondii antibodies were found in 37 (14.56%) of 254 camels with titers of 1:20 in 7, 1:40 in 6, 1:80 in 8, 1:160 in 1, 1:200 in 4, 1:400 in …

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The Application Of A Phosphorus Mass Balance Model For Estimating The Carrying Capacity Of Lake Kariba, Lindah Mhlanga, Wilson Mhlanga, Paul Mwera Jan 2013

The Application Of A Phosphorus Mass Balance Model For Estimating The Carrying Capacity Of Lake Kariba, Lindah Mhlanga, Wilson Mhlanga, Paul Mwera

Turkish Journal of Veterinary & Animal Sciences

The aim of this study was to use an empirical mass balance equation to estimate the carrying capacity of Lake Kariba, where cage culture for Nile tilapia Oreochromis niloticus has been practiced since 1996. The carrying capacity for the lake was estimated at 33.2 × 103 t per year using the Dillon-Rigler phosphorus budget model.

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Detection Of Fecal Coronavirus Antigen In Diarrheic Calves Of High- And Average-Producing Holstein Dairy Cows, Khalil Badiei, Mehrdad Pourjafar, Mohsen Ghane Jan 2013

Detection Of Fecal Coronavirus Antigen In Diarrheic Calves Of High- And Average-Producing Holstein Dairy Cows, Khalil Badiei, Mehrdad Pourjafar, Mohsen Ghane

Turkish Journal of Veterinary & Animal Sciences

From January to December 2009, 661 fecal samples from natural cases of diarrheic calves were taken by veterinary staff from the Department of Large Animal Internal Medicine of Shiraz Veterinary School and veterinary practitioners in Fars Province, Iran. The samples were taken from 267 diarrheic calves of high-producing dairy cows (HPDCs) and 394 diarrheic calves of average-producing Holstein dairy cows (APDCs). Fecal samples were collected and submitted for the laboratory diagnosis of coronavirus antigens. Herd selection was based on geographical location and density of cattle in the region. All herds had HPDC and APDC coronavirus-infected diarrheic calves in their population. …

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Comparative Diagnostic Methods For Canine Ehrlichiosis, Chetan Parmar, Riddhi Pednekar, Anant Jayraw, Mukulesh Gatne Jan 2013

Comparative Diagnostic Methods For Canine Ehrlichiosis, Chetan Parmar, Riddhi Pednekar, Anant Jayraw, Mukulesh Gatne

Turkish Journal of Veterinary & Animal Sciences

The efficacy of blood and buffy coat smear examination, commercially available dot-enzyme-linked immunosorbent assay (ELISA) kit, and nested polymerase chain reaction (PCR) was evaluated in the diagnosis of canine ehrlichiosis in 40 dogs exhibiting symptoms suggestive of the disease. The intracytoplasmic rickettsial organisms were seen in the smears of only 1 dog (2.5%) with an extremely low level of parasitemia. Nested PCR with 16S rRNA revealed characteristic 378 bp bands indicating positive reaction in 8 (20.0%) dogs and sera samples of 21 (52.5%) dogs revealed anti-Ehrlichia antibodies. The dog that revealed organisms in the blood also showed positive results with …

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Clinical Characteristics, Hematology, And Biochemical Analytes Of Primary Omasal Impaction In Bovines, Syed Aashiq Hussain, Sanjeev Kumar Uppal, Charanjit Randhawa, Naresh Kumar Sood, Shashi Kant Mahajan Jan 2013

Clinical Characteristics, Hematology, And Biochemical Analytes Of Primary Omasal Impaction In Bovines, Syed Aashiq Hussain, Sanjeev Kumar Uppal, Charanjit Randhawa, Naresh Kumar Sood, Shashi Kant Mahajan

Turkish Journal of Veterinary & Animal Sciences

This study was conducted on 11 animals (7 buffaloes and 4 cows) diagnosed with primary omasal impaction. In all the cases, laparorumenotomy was performed and omasal impaction was confirmed based on the consistency of the omasal contents along with an empty abomasum. Signalment, history, clinical signs, clinic-pathologic findings, and treatment were determined. Clinical examination was found to be helpful in subjective assessment of omasal impaction but could not aid in definitive diagnosis. Pain on palpation of the omasal area along with rectal findings could be a diagnostic feature. Neutrophilic leukocytosis was observed in a majority of animals. Total bilirubin, glucose, …

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Morphological Similarities Between Spanish Pigeon Breeds., Pere Miquel Parés I Casanova Jan 2013

Morphological Similarities Between Spanish Pigeon Breeds., Pere Miquel Parés I Casanova

Turkish Journal of Veterinary & Animal Sciences

Relationships among 30 pigeon breeds were studied using data from 31 morphological characteristics. The relationships between breeds obtained from the study were rather congruent with the classification used by fanciers groups. The average Euclidean distance between pigeon breeds was 0.93 ± 0.16 STD. The results obtained were very compatible with those described in the literature for each classificatory group. Three large, perfectly definite clusters could be observed in this tree. A cluster was formed by Balearic nonpouter breeds and the Catalan Bare Pigeon. Another cluster occupied an intermediate position and was formed by thief pouters. They shared some remarkable peculiar …

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Presence Of Mycoplasmas In The Respiratory System Of Small Ruminants Managed Under An Extensive Production System, Zinka Maksimovic, Christian De La Fe, Maid Rifatbegovic Jan 2013

Presence Of Mycoplasmas In The Respiratory System Of Small Ruminants Managed Under An Extensive Production System, Zinka Maksimovic, Christian De La Fe, Maid Rifatbegovic

Turkish Journal of Veterinary & Animal Sciences

The objective of this study was to investigate the presence of mycoplasmas in the respiratory system of sheep and goat populations managed under extensive production systems. Specific culture and polymerase chain reaction techniques were performed on a total of 88 lung tissue samples and 142 nasal swabs obtained from multiple herds in Bosnia and Herzegovina. A total of 29 samples (12.6%) were found to be positive for mycoplasmas. Mycoplasma ovipneumoniae was detected in the nasal swabs and lungs of affected sheep (n = 19) and in the lungs of asymptomatic goat kids (n = 2), while M. arginini (n = …

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The 'Federal Law Of Marriage': Deference, Deviation, And Doma, W. Burlette Carter Jan 2013

The 'Federal Law Of Marriage': Deference, Deviation, And Doma, W. Burlette Carter

GW Law Faculty Publications & Other Works

The article discusses the history of federal inroads into marriage by examining federal interventions during the nineteenth and early twentieth century, argues that, in some cases but not all, marriages' federal benefits are indeed intended to support natural procreation, argues that DOMA's underlying statutes are key to ascertaining the purposes of federal marriage benefits and burdens, distinguishes sexual orientation discrimination from race discrimination and offers a proposal for dealing with equal protection challenges to denials of marriage rights to same sex couples. The proposal, which depends upon dual standards of review, recognizes the historical denial of family rights to same …

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Who's The Father?, Naomi R. Cahn, June Carbone Jan 2013

Who's The Father?, Naomi R. Cahn, June Carbone

GW Law Faculty Publications & Other Works

As this brief online essay observes, the litigation that produced the Supreme Court' 2013 decision in Adoptive Couple v. Baby Girl demonstrates why we are no closer to a definitive resolution of what to do when parents do not share assumptions about how to raise their child. The case illustrates the national lack of agreement on what makes someone a parent. At the core of these differences is the question of how to align parental behavior with the promotion of the child’s interest in stable and secure relationships.

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Ecotoxicological Assessment Of Silica And Polystyrene Nanoparticles Assessed By A Multitrophic Test Battery, Maria Casado-Gavalda, Ailbhe Macken, Hugh Byrne Jan 2013

Ecotoxicological Assessment Of Silica And Polystyrene Nanoparticles Assessed By A Multitrophic Test Battery, Maria Casado-Gavalda, Ailbhe Macken, Hugh Byrne

Articles

The acute ecotoxicity of different diameters of silica and polyethyleneimine polystyrene (PS-PEI)nanoparticles (NPs)was assessed on a test battery of aquatic organisms representing different trophic levels. Daphnia magna, Thamnocephalus platyurus, Pseudokirchneriella subcapitata and Vibrio fischeri, were employed in a series of standard acute ecotoxicity tests and work was complemented with two cytotoxicological end points on a rainbow trout gonadal cell line (RTG-2). Physico-chemical characterization of the NPs was performed in the different test media employed, using dynamic light scattering (DLS) and zeta potentiometry. In contrast to silica NPs exposure, for which no effect was observed for concentrations up …

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Pulmonary Dwcnt Exposure Causes Sustained Local And Low-Level Systemic Inflammatory Changes In Mice, Furong Tian, Junja C. Habel-Ungewitter, Yin Renfu, Tobias Stoger Jan 2013

Pulmonary Dwcnt Exposure Causes Sustained Local And Low-Level Systemic Inflammatory Changes In Mice, Furong Tian, Junja C. Habel-Ungewitter, Yin Renfu, Tobias Stoger

Articles

Carbon nanotubes (CNTs) represent promising vectors to facilitate cellular drug delivery and to overcome biological barriers, but some types may also elicit persistent pulmonary inflammation based on their fibre characteristics. Here, we show the pulmonary response to aqueous suspensions of block copolymer dispersed, double-walled carbon nanotubes (DWCNT, length 1–10 lm) in mice by bronchoalveolar lavage (BAL) analysis, and BAL and blood cytokine and lung antioxidant profiling. The intratracheally instilled dose of 50 lg DWCNT caused significant pulmonary inflammation that was not resolved during a 7- day observation period. Light microscopy investigation of the uptake of DWCNT agglomerates revealed no particle …

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Brief Communication: Evolution Of A Specific O Allele (O1vg542a) Supports Unique Ancestry Of Native Americans, Fernando A. Villanea, Deborah A. Bolnick, Cara Monroe, Rosita Worl, Rosemary Cambra, Alan M. Leventhal, Brian M. Kemp Jan 2013

Brief Communication: Evolution Of A Specific O Allele (O1vg542a) Supports Unique Ancestry Of Native Americans, Fernando A. Villanea, Deborah A. Bolnick, Cara Monroe, Rosita Worl, Rosemary Cambra, Alan M. Leventhal, Brian M. Kemp

Faculty Publications, Urban and Regional Planning

In this study, we explore the geographic and temporal distribution of a unique variant of the O blood group allele called O1vG542A, which has been shown to be shared among Native Americans but is rare in other populations. O1vG542A was previously reported in Native American populations in Mesoamerica and South America, and has been proposed as an ancestry informative marker. We investigated whether this allele is also found in the Tlingit and Haida, two contemporary indigenous populations from Alaska, and a pre-Columbian population from California. If O1vG542A is present in Na-Dene speakers (i.e., Tlingits), it would indicate that Na-Dene speaking …

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Tort's Response To Surrogate Motherhood: Providing Surrogates With A Remedy For Breached Agreements Jan 2013

Tort's Response To Surrogate Motherhood: Providing Surrogates With A Remedy For Breached Agreements

UBC Law Review

No abstract provided.

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Opposing Mr. Big In Principle Jan 2013

Opposing Mr. Big In Principle

UBC Law Review

No abstract provided.

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Local Adaptation Of Two Cryptic Species, Lasthenia Californica And Lasthenia Gracilis, To Distinct Regions Within A Serpentine Outcrop, Teri Barry Jan 2013

Local Adaptation Of Two Cryptic Species, Lasthenia Californica And Lasthenia Gracilis, To Distinct Regions Within A Serpentine Outcrop, Teri Barry

Master's Theses

Intraspecific variation providing tolerance to specific edaphic conditions may contribute to population differentiation, speciation, and species coexistence. This process is often examined using reciprocal transplant experiments of closely related species in contrasting edaphic conditions. The two cryptic species Lasthenia californica and L. gracilis occur on a serpentine outcrop in parapatry at Jasper Ridge Biological Preserve. I hypothesized that each species would demonstrate greater fitness in its home range. A reciprocal transplant experiment was conducted in the field to determine home site advantage. Seedlings from each species were planted in both home ranges and in the transition zone where both species …

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The Intergenerational Transmission Of Attitudes On Divorce And Marriage, Rebecca Elizabeth Bivona-Guttadauro Jan 2013

The Intergenerational Transmission Of Attitudes On Divorce And Marriage, Rebecca Elizabeth Bivona-Guttadauro

Master's Theses

The present study shed light on the process of intergenerational transmission of attitudes as it occurs for women from divorced and intact families. Taking into account how women from divorced and intact homes view their parents' relationship, this study examined how attitudes of marriage and divorce are transmitted from parents to children. This study utilized quantitative survey methods including surveys to gather data and nested multiple linear regression to analyze the data to determine how the process of intergenerational transmission of attitudes was occurring, if at all, for the women in the sample. Utilizing sample data from a large public …

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A Girlhood Of Myth, Dreams, And Trauma: Redefining The Asian North American Female Bildungsroman, Danielle Brianna Crawford Jan 2013

A Girlhood Of Myth, Dreams, And Trauma: Redefining The Asian North American Female Bildungsroman, Danielle Brianna Crawford

Master's Theses

This thesis examines the use of myth, dreams, and historical trauma within the genre of the Asian North American female bildungsroman. In an attempt to redefine the contested genre of the ethnic bildungsroman, this study analyzes three novels by Asian American and Asian Canadian female authors: Cecilia Manguerra Brainard's When the Rainbow Goddess Wept (1991), Joy Kogawa's Obasan (1981), and Lan Cao's Monkey Bridge (1997). Each of these novels is an ethnic bildungsroman that highlights the identity formation of a female protagonist in the midst of historical trauma. This study focuses on the ways in which these texts resist the …

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Immobilization Of Rhodococcus Erythropolis As A Potential Treatment For Atherosclerosis, Srikanth Darbha Jan 2013

Immobilization Of Rhodococcus Erythropolis As A Potential Treatment For Atherosclerosis, Srikanth Darbha

Master's Theses

Cardiovascular disease is the leading cause of death in the United States and isprimarily due to hypercholesterolemia. The novel approach of combatting atherosclerosis presented in this research entails delivery of microencapsulated Rhodococcus erythropolis immobilized in biodegradable alginate-based microcapsules and utilizing the bacterium's cholesterol oxidase enzyme pathway to degrade cholesterol from intermediate-stage arterial plaque. The bacterial growth medium was optimized using Taguchi design methods to enable growth characterizations hindered by biosurfactant by-product. Methodologies for extraction and quantification of biosurfactant and cholesterol were developed and conducted simultaneous to bacterial growth assessment. Bacteria were encapsulated using atomization (850±50 μm) and inkjet bioprinting (32±5 …

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