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Wetting And Drying Cycles And The Fungal Communities On Leaf Litter In Streams, Kele Qwinn Thrailkill

Masters Theses

"Leaf litter is a major source of energy for streams in deciduous forests. Fungi play a critical role by converting the leaves into nutritional material for the rest of the food web. The breakdown of leaf litter and associated biota, including invertebrates and fungi, have been proposed as measures of stream health in systems affected by anthropogenic activity. Rates of leaf breakdown can be depressed in streams affected by acidity, metals, organic contaminants, and other stressors. Climate change may lead to alterations in stream hydrology such that streams experience more frequent floods as well as drying episodes. Fungal communities can …

Insufficient Ct Data Reconstruction Based On Directional Total Variation (Dtv) Regularized Maximum Likelihood Expectation Maximization (Mlem) Method, Fahima Fahmida Islam

Masters Theses

"Sparse tomography is an efficient technique which saves time as well as minimizes cost. However, due to few angular data it implies the image reconstruction problem as ill-posed. In the ill posed problem, even with exact data constraints, the inversion cannot be uniquely performed. Therefore, selection of suitable method to optimize the reconstruction problems plays an important role in sparse data CT. Use of regularization function is a well-known method to control the artifacts in limited angle data acquisition. In this work, we propose directional total variation regularized ordered subset (OS) type image reconstruction method for neutron limited data CT. …

Role Of Nicotine In Oxidative Stress, Rakesh Kacham

Masters Theses

"Nicotine, a major alkaloid, is present in tobacco products as well as in smaller amounts in potatoes, tomatoes, and eggplants. Although it is the addictive compound in cigarettes, nicotine is believed to play a protective role in neurodegenerative disorders such as Parkinson's disease. Researchers have found that the short-term administration of nicotine may help improve the memory process by reducing oxidative stress in the brain. Our studies have shown that, by blocking Fenton's reaction, nicotine is able to inhibit free radical generation, so this research has focused on the antioxidant properties of nicotine. The cell lines of the alveoli, blood …

Editorial-The 4th International Workshop On Modeling The Ocean (Iwmo 2012), Lie-Yauw Oey, Yasumasa Miyazawa, Hidenori Aiki, Yukio Masumoto, Tal Ezer, Takuji Waseda

CCPO Publications

The 4th International Workshop on Modeling the Ocean (IWMO; http://www.jamstec.go.jp/frcgc/jcope/htdocs/e/ iwmo2012.html) was held on May 21–24, 2012 in the vibrant city of Yokohama on the Tokyo Bay, Japan. The Workshop was hosted by Japan Agency for Marine-Earth Science and Technology (JAMSTEC)—the home of the famous “Earth Simulator”—one of the world's most powerful supercomputers dedicated for simulating the complex interactive processes of the earth and its environment.

Kinetics Of Human And Bovine Insulin Amyloid Fibril Formation In The Presence Of Solid/Liquid Interfaces, Paulina Barranco Morales

Masters Theses

"The purpose of this thesis was to study the rate and extent of aggregation of human and bovine insulin in bulk and in the presence of either polystyrene microspheres with different surface chemistries or liposomes of different composition. Insulin aggregation was followed by turbidimetry, Fourier transform infrared spectroscopy (FTIR), and dynamic light scattering. The Congo red assay was used to corroborate the presence of amyloid deposits and transmission electron microscopy (TEM) was used to analyze the morphology of the amyloid deposits. Our results show that not all the surfaces shortened the lag time. On the other hand, most surfaces had …

Protein Aggregation At Solid/Liquid Interfaces: A Monte Carlo Study With Explicit And Implicit Solvent Effects, Rehman Fazeem

Masters Theses

"Metropolis Monte Carlo (MC) simulations were performed with positively charged peptides in aqueous solution to study changes in peptide conformations at solid/liquid interface, and its effects on protein aggregation. Intermediate-resolution diblock model peptide, comprising of 10 units of ALA (non-polar) and LYS (polar) amino acid residues, was used for the simulations. In the first approach to modeling, solvent effects were considered explicitly. The explicit model was then used to study two peptide molecules, in helical structure, at solid/liquid interface. In order to increase the number of peptide molecules in the simulation box, with reduced computational cost, an implicit solvent model …

A Study Of Clustering Rssi And Lqi From Wireless Network Communications, Yanwen Wang

Masters Theses

"In today's information world, different wireless sensor network topologies are permitted to exist in the same geographical region. For example, a city contains thousands of enterprise networks; a school might include different wireless network topologies used by students and faculties respectively. Even within a building, there might be multiple companies that use their own wireless networks. These networks might cause interference to other networks. How to detect, determine and locate the unknown wireless topologies in the same geographical area becomes quite significant in the wireless industry, especially in military use, such as spy-nodes detection and communication orientation systems. In this …

Broad-Spectrum Antibacterial Properties Of Metal-Ion Doped Borate Bioactive Glasses For Clinical Applications, Megan Ottomeyer

Masters Theses

"Bioactive glasses with antimicrobial properties can be implemented as coatings on medical devices and implants, as well as a treatment for tissue repair and prevention of common hospital-acquired infections such as MRSA A borate-containing glass, B3, is also undergoing clinical trials to assess wound-healing properties. The sensitivities of various bacteria to B3, B3-Ag, B3-Ga, and B3-I bioactive glasses were tested. In addition, the mechanism of action for the glasses was studied by spectroscopic enzyme kinetics experiments, Live-Dead staining fluorescence microscopy, and luminescence assays using two gene fusion strains of Escherichia coli.

It was found that gram-positive bacteria were more …

Theory, Measurement And Hard Times: Some Issues For Hiv/Aids Research, Samuel R. Friedman, Milagros Sandoval, Pedro Mateu-Gelabert, Diana Rossi, Marya Gwadz, Kirk Dombrowski, Pavlo Smyrnov, Tetyana Basylyeva, Enrique R. Pouget, David Perlman

Department of Sociology: Faculty Publications

Economic and political instability and related “big events” are widespread throughout the globe. Although they sometimes lead to epidemic HIV outbreaks, sometimes they do not—and we do not understand why. Current behavioural theories do not adequately address these processes, and thus cannot provide optimal guidance for effective intervention. Based in part on a critique of our prior “pathways” model of big events, we suggest that cultural–historical activity theory (CHAT) may provide a useful framework for HIV research in this area. Using CHAT concepts, we also suggest a number of areas in which new measures should be developed to make such …

Out On The Land: Income, Subsistence Activities, And Food Sharing Networks In Nain, Labrador, Kirk Dombrowski, Emily Channell, Bilal Khan, Joshua Moses, Evan Misshula

Department of Sociology: Faculty Publications

In recent Inuit ethnography, a major concern has been how and to what extent contemporary Inuit participate in and depend on subsistence activities, particularly in the context of increasing wage employment and growing participation in the cash economy. This paper provides an analysis of these activities in the predominately Inuit community of Nain, Labrador. Using social network data and demographic information collected between January and June 2010, we examine the interconnections between subsistence activities—obtaining “country food” through activities such as hunting, fishing, and collecting—with access to the means of obtaining subsistence resources (such as snow mobiles, cabins, and boats), employment …

Adolescent Loneliness And Health In Early Adulthood, Bridget J. Goosby, Anna Bellatorre, Katrina M. Walsemann, Jacob Cheadle

Department of Sociology: Faculty Publications

The health consequence of loneliness in the early life course is an understudied topic in the sociological literature. Using data from Waves 1–3 of the National Longitudinal Study of Adolescent Health, we examine pre-disease pathways in the relationship between adolescent loneliness and early adult health. Our results indicate that loneliness during adolescence is associated with diagnosed depression, poorer adult self-rated health, and metabolic risk factors related to cardiovascular disease. High depressive symptoms and parent support are important pathways through which the health consequences of loneliness are exacerbated or offset. There is also evidence that lonely youth remain at higher risk …

Untitled Chapter, William Snape

Contributions to Books

No abstract provided.

Olanzapine Sensitization And Clozapine Tolerance: From Adolescence To Adulthood In The Conditioned Avoidance Response Model, Jing Qiao, Hong Li, Ming Li

Department of Psychology: Faculty Publications

Disruption of conditioned avoidance response (CAR) in rodents is one trademark feature of many antipsychotic drugs. In adult rats, repeated olanzapine (OLZ) treatment causes an enhanced disruption of avoidance response (sensitization), whereas repeated clozapine (CLZ) treatment causes a decreased disruption (tolerance). The present study addressed (1) whether OLZ sensitization and CLZ tolerance can be induced in adolescent rats, and (2) the extent to which OLZ sensitization and CLZ tolerance induced in adolescence persists into adulthood. Male adolescent Sprague–Dawley rats (approximate postnatal days (BP) 43–47) were first treated with OLZ (1.0 or 2.0 mg/kg, subcutaneously (sc)) or CLZ (10 or 20 …

Avoidance Disruptive Effect Of Clozapine And Olanzapine Is Potentiated By Increasing The Test Trials: Further Test Of The Motivational Salience Hypothesis, Min Feng, Nan Sui, Ming Li

Department of Psychology: Faculty Publications

Antipsychotic drugs suppress animals’ ability to avoid an aversive stimulus in the conditioned avoidance response model (CAR). This behavioral effect is thought to reflect antipsychotic activity and is suggested to be mediated by a drug’s action in attenuating the motivational salience of a conditioned stimulus (CS). In the present study, we tested whether atypical antipsychotic drugs clozapine and olanzapine act through this behavioral mechanism by manipulating the number of avoidance test trials. We reasoned that more CS trials in the present of clozapine or olanzapine would afford the drug more opportunities to decrease the motivational salience of the CS, thus …

Wildlife In Airport Environments: Chapter 2 Behavior And Physiologyin The Development And Application Of Visual Deterrents At Airports, Bradley F. Blackwell, Esteban Fernandez-Juricic

United States Department of Agriculture Wildlife Services: Staff Publications

In the first major treatise on the science of wildlife damage management, Conover (2002) dedicated a short review of visual stimuli used to deter wildlife from specific areas or resources. The brevity of the review reflects the fact that these techniques have traditionally been developed over short periods and used to confront an immediate problem, generally through trial and error. Because humans perceive visual stimuli differently than other animals (Schwab 2012), deterrents based on human perception likely fall short in saliency of the stimuli (Le., how well the stimuli stand out against a background). However, assessment of visual stimuli (both …

Wildlife In Airport Environments: Chapter 14 Avian Survey Methods For Use At Airports, Bradley F. Blackwell, Paige M. Schmidt, James A. Martin

United States Department of Agriculture Wildlife Services: Staff Publications

Adverse effects and damage caused by interactions between humans and wildlife are increasing (DeStephano and DeGraaf 2003). To manage wildlife effectively- whether to mitigate damage, to enhance safety, or to reach conservation goals-wildlife biologists must identify hazards posed by or to members of a particular species (Le., a population) or guild, and then prioritize management goals and specific actions. We examine the special problem of managing birds to reduce hazards to aviation, particularly those species known to cause structural damage to aircraft when struck and that pose problems to airport facilities (Dolbeer et al. 2000, Cleary and Dolbeer 2005, DeVault …

Wildlife In Airport Environments: Chapter 3 Effectiveness Of Chemical Repellents In Managing Birds At Airports, Larry Clark, Michael L. Avery

United States Department of Agriculture Wildlife Services: Staff Publications

Repellents include methods and devices used to manipulate behavior of animals to reduce damage or nuisance. Critical to the design and success of repellents is understanding how sensory modalities mediate perception of signals, and how ecological context and sensory inputs influence animal learning. A repellent's success is tied to the axiom of using the proper tool for the proper job. When repellents "fail," it is almost always because wildlife managers have not appropriately matched signal, receiving systems, message, and context. Reconciling such considerations can be a complex process. In this chapter we review components and processes essential for the successful …

Food Availability Of Glucose And Fat, But Not Fructose, Increased In The Us Between 1970 And 2009: Analysis Of The Usda Food Availability Data System, Trevor J. Carden, Timothy P. Carr

Department of Nutrition and Health Sciences: Faculty Publications

Background: Obesity rates in the United States have risen consistently over the last four decades, increasing from about 13% of the population in 1970 to more than 34% in 2009. Dietary fructose has been blamed as a possible contributor to the obesity increase, although the consumption pattern of fructose and other key nutrients during this 40 year period remains a topic of debate. Therefore, we analyzed the USDA Loss-Adjusted Food Availability Database in combination with the USDA Nutrient Database for Standard Reference (Release 24) to determine whether fructose consumption in the US has increased sufficiently to be a casual …

Echium Oil Reduces Plasma Triglycerides By Increasing Intravascular Lipolysis In Apob100-Only Low Density Lipoprotein (Ldl) Receptor Knockout Mice, Lolita M. Forrest, Christopher M. Lough, Soonkyu Chung, Elena Y. Boudyguina, Abraham K. Gebre, Thomas L. Smith, Perry L. Colvin, John S. Parks

Department of Nutrition and Health Sciences: Faculty Publications

Echium oil (EO), which is enriched in SDA (18:4 n-3), reduces plasma triglyceride (TG) concentrations in humans and mice. We compared mechanisms by which EO and fish oil (FO) reduce plasma TG concentrations in mildly hypertriglyceridemic male apoB100-only LDLrKO mice. Mice were fed one of three atherogenic diets containing 0.2% cholesterol and palm oil (PO; 20%), EO (10% EO + 10% PO), or FO (10% FO + 10% PO). Livers from PO- and EO-fed mice had similar TG and cholesteryl ester (CE) content, which was significantly higher than in FO-fed mice. Plasma TG secretion was reduced in FO vs. EO-fed …

Surveillance And Movements Of Virginia Opossum (Didelphis Virginiana) In The Bovine Tuberculosis Region Of Michigan, W. D. Walter, J. W. Fischer, C. W. Anderson, D. R. Marks, T. J. Deliberto, S. Robbe-Austerman, K. C. Vercauteren

United States Department of Agriculture Wildlife Services: Staff Publications

Wildlife reservoir hosts of bovine tuberculosis (bTB) include Eurasian badgers (Meles meles) and brushtail possum (Trichosurus vulpecula) in the UK and New Zealand, respectively. Similar species warrant further investigation in the northern lower peninsula of Michigan, USA due to the continued presence of bTB on cattle farms. Most research in Michigan, USA has focused on interactions between white-tailed deer (Odocoileus virginianus) and cattle (Bos taurus) for the transmission of the infectious agent of bTB, Mycobacterium bovis, due to high deer densities and feeding practices. However, limited data are available on medium-sized mammals …

A Comprehensive, Multi-Scale Dynamical Model Of Erbb Receptor Signal Transduction In Human Mammary Epithelial Cells, Tomáš Helikar, Naomi Kochi, Bryan Kowal, Manjari Dimri, Mayumi Naramura, Srikumar M. Raja, Vimla Band, Hamid Band, Jim A. Rogers

Department of Biochemistry: Faculty Publications

The non-receptor tyrosine kinase Src and receptor tyrosine kinase epidermal growth factor receptor (EGFR/ErbB1) have been established as collaborators in cellular signaling and their combined dysregulation plays key roles in human cancers, including breast cancer. In part due to the complexity of the biochemical network associated with the regulation of these proteins as well as their cellular functions, the role of Src in EGFR regulation remains unclear. Herein we present a new comprehensive, multi-scale dynamical model of ErbB receptor signal transduction in human mammary epithelial cells. This model, constructed manually from published biochemical literature, consists of 245 nodes representing proteins …

A Framework For Managing Airport Grasslands And Birds Amidst Conflicting Priorities, Bradley F. Blackwell, Thomas W. Seamans, Paige M. Schmidt, Travis L. Devault, Jerrold L. Belant, Mark J. Whittingham, James A. Martin, Esteban Fernández-Juricic

United States Department of Agriculture Wildlife Services: Staff Publications

Management of modern airports is a task beset by conflicting priorities. Airports are vital to the global market economy, but impose costly environmental disturbances including habitat loss, noise, reduced air quality, erosion, introduction of invasive organisms, and polluted storm-water runoff (Blackwell et al. 2009). Airport environments also attract some wildlife hazardous to aviation safety, namely species involved in wildlife-aircraft collisions or ‘strikes’ (ICAO 2001, Blackwell et al. 2009, DeVault et al. 2011). Since 1912 at least 276 human lives have been lost due to bird strikes (Thorpe 2010), and from 1990 to 2010, more than 106 000 bird strikes involving …

Evolutionary Characterization Of The Pandemic H1n1/ 2009 Influenza Virus In Humans Based On Non-Structural Genes, Chengmin Wang, Yanyu Zhang, Bin Wu, Shelan Liu, Ping Xu, Yanmin Lu, Jing Luo, Dale L. Nolte, Thomas J. Deliberto, Mingxing Duan, Hong Zhang, Hongxuan He

United States Department of Agriculture Wildlife Services: Staff Publications

The 2009 influenza pandemic had a tremendous social and economic impact. To study the genetic diversity and evolution of the 2009 H1N1 virus, a mutation network for the non-structural (NS) gene of the virus was constructed. Strains of the 2009 H1N1 pandemic influenza A virus could be divided into two categories based on the V123I mutation in the NS1 gene: G1 (characterized as 123 Val) and G2 (characterized as 123 Ile). Sequence homology analysis indicated that one type of NS sequence, primarily isolated from Mexico, was likely the original type in this pandemic. The two genotypes of the virus presented …

Comparison Of Two Models For Estimating Mortality From Baitings With Compound Drc-1339 Concentrate Avicide, H. Jeffrey Homan, Randal S. Stahl, George M. Linz

United States Department of Agriculture Wildlife Services: Staff Publications

In the U.S., DRC-1339 baitings for blackbirds (Icteridae) are generally done under the pesticide label, Compound DRC-1339 Concentrate ‒ Staging Areas. DRC-1339 is a slow-acting avicide and gives the birds enough time to leave the baiting sites. Carcass searches and other forms of onsite counts are ineffective. Instead, linear models (LM) are used. The LM are based on esophageal analyses of several blackbird species collected while feeding at staging area bait sites. Biases and large variances can occur with this type of sampling. As an alternative to the LM, we developed a semi-mechanistic model (SM) that combined mechanistic modeling of …

Rethinking Airport Land-Cover Paradigms: Agriculture, Grass, And Wildlife Hazards, Travis L. Devault, Michael J. Begier, Jerrold L. Belant, Bradley F. Blackwell, Richard A. Dolbeer, James A. Martin, Thomas W. Seamans, Brian E. Washburn

United States Department of Agriculture Wildlife Services: Staff Publications

The various habitats that compose airport property, particularly undeveloped lands, inherently contribute in some measure to attraction of wildlife and, subsequently, the risk of wildlife–aircraft collisions. Many airports control large tracts of land outside airoperations areas for safety and security and to mitigate noise pollution. In the contiguous United States, the average size of airports that are approved for regularly scheduled passenger traffic (i. e., certificated) by the Federal Aviation Administration (FAA) is 761 ha (DeVault et al. 2012). Although airports operate under numerous constraints when selecting land covers (Federal Aviation Administration 2012), turf grasses (managed, domesticated grass varieties) and …

Wiidiife Translocation As A Management Alternative At Airports, Paul D. Curtis, Jonathon D. Cepek, Rebecca Mihalco, Thomas W. Seamans, Scott R. Craven

United States Department of Agriculture Wildlife Services: Staff Publications

Wildlife in urban settings may be a welcome sight for many, but negative interactions between people and various wild species are increasing (Conover et a!. 1995, Conover 2002). Wildlife populations are commonly managed in part to reduce these conflicts, particularly in high-risk areas such as roadways and airports (Conover 2002). However, the public often opposes lethal control or management methods perceived as causing harm to nuisance animals (Reiter et al. 1999, Conover 2002, Treves et al. 2006), and attitudes vary considerably depending on the particular wildlife species involved (Kretser et a!. 2009). Consequently, a variety of nonlethal management approaches are …

Report To The Chicago Park District On Conflicts With Ring-Billed Gulls And The 2013 Integrated Ring-Billed Gull Damage Management Project, J. W. Hartmann, T. G. Guerrant, S. F. Beckerman, R. M. Engeman, T. W. Seamans

United States Department of Agriculture Wildlife Services: Staff Publications

The large ring-billed gull (Larus delawarensis) population in the City of Chicago has caused various conflicts including general nuisance, property damage, economic losses, and threats to human health and safety. Several studies have shown a relationship between ring-billed gulls and increased levels of fecal indicator bacteria (FIB) such as Escherichia coli (E. coli) in nearshore waters. Results of tests for E. coli have led to the issuance of swim advisories at Chicago beaches.

The objectives of the Chicago Ring-billed Gull Damage Management Project were to (1) reduce the local production of ring-billed gulls, (2) reduce the severity of …

References From Landslide Ecology, Lawrence R. Walker, Aaron B. Shiels

United States Department of Agriculture Wildlife Services: Staff Publications

No abstract provided.

Glutaredoxin-2 Is Required To Control Proton Leak Through Uncoupling Protein-3, Ryan J. Mailloux, Jian Ying Xuan, Brittany Beauchamp, Marjorie F. Lou, Mary-Ellen Harper

School of Veterinary and Biomedical Sciences: Faculty Publications

Glutathionylation has emerged as a key modification required for controlling protein function in response to changes in cell redox status. Recently, we showed that the glutathionylation state of uncoupling protein-3 (UCP3) modulates the leak of protons back into the mitochondrial matrix, thus controlling reactive oxygen species production. However, whether or not UCP3 glutathionylation is mediated enzymatically has remained unknown because previous work relied on the use of pharmacological agents, such as diamide, to alter the UCP3 glutathionylation state. Here, we demonstrate that glutaredoxin-2 (Grx2), a matrix oxidoreductase, is required to glutathionylate and inhibit UCP3. Analysis of bioenergetics in skeletal muscle …

Accessory Genes Confer A High Replication Rate To Virulent Feline Immunodeficiency Virus, Ryan M. Troyer, Jesse Thompson, John H. Elder, Sue Vandewoude

School of Veterinary and Biomedical Sciences: Faculty Publications

Feline immunodeficiency virus (FIV) is a lentivirus that causes AIDS in domestic cats, similar to human immunodeficiency virus (HIV)/AIDS in humans. The FIV accessory protein Vif abrogates the inhibition of infection by cat APOBEC3 restriction factors. FIV also encodes a multifunctional OrfA accessory protein that has characteristics similar to HIV Tat, Vpu, Vpr, and Nef. To examine the role of vif and orfA accessory genes in FIV replication and pathogenicity, we generated chimeras between two FIV molecular clones with divergent disease potentials: a highly pathogenic isolate that replicates rapidly in vitro and is associated with significant immunopathology in vivo, …