Digital Commons Network^™

Kinase Suppressor Of Ras 1 Is Not Required For The Generation Of Regulatory And Memory T Cells, Marie Le Borgne, Erin L. Filbert, Andrey S. Shaw

Open Access Publications

No abstract provided.

The Comparative Morphology Of The Pectoral Free Rays In Scorpaenoid Fishes (Perciformes: Scorpaenoidea)), Jeremy Peter Harris

Master's Theses

The pectoral fins of many benthic taxa have evolved many unique features used to interact with the substrate. In one such group, the searobins (Triglidae: Scorpaenoidea), three of the pectoral fin rays have become separated from the fin as a whole, allowing them to operate as a separate appendage from the fin as a whole. The anatomical structure of these "free rays" was investigated and several previously unreported muscle and bone variations were found. This method was extended to include members of four other scorpaenoid families which possess free rays, which revealed important differences in the muscle, bone, and nervous …

Analysis Of The Minimal Promoter From The Hatching Enzyme A Gene, Anna Matejczyk

Master's Theses

Hatching, defined as a biochemical or biophysical mechanism that allows the embryo to leave its protective envelope, is found in most animals. In fish, reptiles and amphibians, mostly oviparous animals, this means the emergence of the embryo from an egg. In mammals, viviparous animals, hatching is performed by the blastocyst in order to shed the zona pellucida.

Fish, an oviparous animal, takes advantage of a biochemical mechanism in order to hatch and emerge from their chorion, or egg envelope. The mechanism includes the use of hatching enzymes that are secreted in order to digest the envelope membrane. The genes controlling …

Characterization Of The Mechanical Strength, Resorption Properties, And Histologic Characteristics Of A Fully Absorbable Material (Poly-4-Hydroxybutyrate-Phasix Mesh) In A Porcine Model Of Hernia Repair, Corey R. Deeken, Brent D. Matthews

Open Access Publications

No abstract provided.

Infiltration Of Proinflammatory M1 Macrophages Into The Outer Retina Precedes Damage In A Mouse Model Of Age-Related Macular Degneration, Abdoulaye Sene, Rajendra S. Apte

Open Access Publications

No abstract provided.

Whole Genome Sequence Of The Treponema Fribourg- Blanc: Unspecified Simian Isolate Is Highly Similar To The Yaws Subspecies, Marie Zobanikova, Michal Strouhal, Lenka Mikalova, Darina Cejkova, Lenka Ambrozova, Petra Pospisilova, Lucinda L. Fulton, Lei Chen, Erica Sodergren, George M. Weinstock, David Smajs

Open Access Publications

No abstract provided.

Tissue-Dependent Consequences Of Apc Inactivation On Proliferation And Differentiation Of Ciliated Cell Progenitors Via Wnt And Notch Signaling, Aimin Li, Belinda Chan, Juan C. Felix, Yiming Xing, Min Li, Steven L. Brody, Zea Borok, Changgong Li, Parviz Minoo

Open Access Publications

No abstract provided.

Epcam Expression Varies Significantly And Is Differentially Associated With Prognosis In The Luminal B Her2+, Basal-Like, And Her2 Intrinsic Subtypes Of Breast Cancer, Savas D. Soysal, Simone Muenst, Thanh U. Barbie, Timothy P. Fleming, Feng Gao, Gilbert Spizzo, Daniel Oertli, Carsten T. Viehl, Ellen C. Obermann, William E. Gillanders

Open Access Publications

No abstract provided.

The Quest For Load‐Independent Left Ventricular Chamber Properties: Exploring The Normalized Pressure Phase Plane, Erina Ghosh, Sandor J. Kovacs

Open Access Publications

No abstract provided.

Mated Progeny Production Is A Biomarker Of Aging In Caenorhabditis Elegans, Christopher L. Pickett, Nicholas Dietrich, Junfang Chen, Chengjie Xiong, Kerry Kornfeld

Open Access Publications

No abstract provided.

Zrt1 Harbors An Excess Of Nonsynonymous Polymorphism And Shows Evidence Of Balancing Selection In Saccharomyces Cerevisiae, Elizabeth K. Engle, Justin C. Fay

Open Access Publications

No abstract provided.

Srs2 Prevents Rad51 Filament Formation By Repetitive Motion On Dna, Yupeng Qiu, Edwin Antony, Sultan Doganay, Hye Ran Koh, Timothy M. Lohman, Sua Myong

Open Access Publications

No abstract provided.

Maternal High-Fat Diet Induces Hyperproliferation And Alters Pten/Akt Signaling In Prostates Of Offspring, Emily C. Benesh, Peter A. Humphrey, Qiang Wang, Kelle H. Moley

Open Access Publications

No abstract provided.

Direct Imaging Of Single Uvrd Helicase Dynamics On Long Single-Stranded Dna, Kyung Suk Lee, Hamza Balci, Haifeng Jia, Timothy H. Lohman, Taekjip Ha

Open Access Publications

No abstract provided.

Pattern Recognition Receptor Mda5 Modulates Cd8+ T Cell- Dependent Clearance Of West Nile Virus From The Central Nervous System, Helen M. Lazear, Amelia K. Pinto, Hilario J. Ramos, Sarah C. Vick, Bimmi Shrestha, Mehul S. Suthar, Michael Gale Jr, Michael S. Diamond

Open Access Publications

No abstract provided.

Crl4(Cdt2) Targets Chk1 For Pcna-Independent Destruction, Jiwon Huh, Helen Piwnica-Worms

Open Access Publications

No abstract provided.

Murine Cytomegalovirus Protein Pm79 Is A Key Regulator For Viral Late Transcription, Travis J. Chapa, L. Steven Johnson, Christopher Affolter, Mark C. Valentine, Anthony R. Fehr, Wayne M. Yokoyama, Dong Yu

Open Access Publications

No abstract provided.

Neurotropic Arboviruses Induce Interferon Regulatory Factor 3-Mediated Neuronal Responses That Are Cytoprotective, Interferon Independent, And Inhibited By Western Equine Encephalitis Virus Capsid, Daniel C. Peltier, Helen M. Lazear, Jocelyn R. Farmer, Michael S. Diamond, David J. Miller

Open Access Publications

No abstract provided.

Loss Of Dap12 And Fcrγ Drives Exaggerated Il-12 Production And Cd8(+) T Cell Response By Ccr2(+) Mo-Dcs, Grzegorz B. Gmyrek, Holly M. Akilesh, Daniel B. Graham, Anja Fuchs, Lihua Yang, Mark J. Miller, Gabriel J. Sandoval, Kathleen C. F. Sheehan, Robert D. Schreiber, Michael S. Diamond, Wojciech Swat

Open Access Publications

No abstract provided.

An Allosteric Regulator Of R7-Rgs Proteins Influences Light-Evoked Activity And Glutamatergic Waves In The Inner Retina, Matthew D. Cain, Bradly Q. Vo, Alexander V. Kolesnikov, Vladimir J. Kefalov, Susan M. Culican, Daniel Kerschensteiner, Kendall J. Blumer

Open Access Publications

No abstract provided.

Mblast: Keeping Up With The Sequencing Explosion For (Meta) Genome Analysis, Curtis Davis, Karthik Kota, Venkat Baldhandapani, Wei Gong, Sahar Abubucker, Eric Becker, John Martin, Kristine M. Wylie, Radhika Khetani, Matthew E. Hudson, George M. Weinstock, Makedonka Mitreva

Open Access Publications

No abstract provided.

Hirschsprung-Like Disease Is Exacerbated By Reduced De Novo Gmp Synthesis, Jonathan I. Lake, Olga A. Tusheva, Brittany L. Graham, Robert O. Heuckeroth

Open Access Publications

No abstract provided.

Genome-Wide Distribution Of Histone H4 Lysine 16 Acetylation Sites And Their Relationship To Gene Expression, Nobuo Horikoshi, Pankaj Kumar, Girdhar G. Sharma, Min Chen, Clayton R. Hunt, Kenneth Westover, Shantanu Chowdhury, Tej K. Pandita

Open Access Publications

No abstract provided.

The Western Painted Turtle Genome, A Model For The Evolution Of Extreme Physiological Adaptations In A Slowly Evolving Lineage, Patrick Minx, Kim D. Delehaunty, Catrina C. Fronick, Lucinda Fulton, Tina A. Graves, Ladeana W. Hillier, Cyriac Kandoth, Michelle O'Laughlin, Nay Thane, Wesley C. Warren, Elaine R. Mardis, Richard K. Wilson, Et Al

Open Access Publications

No abstract provided.

Cross-Translational Studies In Human And Drosophila Identify Markers Of Sleep Loss, Matthew S. Thimgan, Laura Gottschalk, Cristina Toedebusch, Jennifer Mcleland, Allan Rechtschaffen, Marcia Gilliland-Roberts, Stephen P. Duntley, Paul J. Shaw

Open Access Publications

No abstract provided.

Synthesis Of Orthogonally Protected Azalanthionines (Lanazanines) By Sequential Ring-Opening Of N-Substituted Aziridine 2-Carboxylates, Keith O'Brien, Keith Ó Proinsias, Fintan Kelleher

Articles

Orthogonally protected azalanthionines (lanazanines, 4-azadiaminopimelic acids or b-aminoalaninoalanines) have been synthesised in good yields by the ring-opening of N-protected aziridine 2-carboxylates with suitably protected diaminopropanoic acids (DAPs). The required DAPs were also synthesised by ring-opening of N-protected aziridine 2-carboxylates with para-methoxybenzylamine.

Deletion Of Fibroblast Growth Factor Receptor 2 From The Peri-Wolffian Duct Stroma Leads To Ureteric Induction Abnormalities And Vesicoureteral Reflux, Kenneth A. Walker, Sunder Sims-Lucas, Valeria E. Di Giovanni, Caitlin Schaefer, Whitney M. Sunseri, Tatiana Novitskaya, Mark P. De Caestecker, Feng Chen, Carlton M. Bates

Open Access Publications

No abstract provided.

Exosomes: Looking Back Three Decades And Into The Future, Clifford V. Harding, John E. Heuser, Philip D. Stahl

Open Access Publications

No abstract provided.

Dual Fluorescent Molecular Substrates Selectively Report The Activation, Sustainability And Reversibility Of Cellular Pkb/Akt Activity, Duanwen Shen, Mingfeng Bai, Rui Tang, Baogang Xu, Xiaoming Ju, Richard G. Pestell, Samuel Achilefu

Open Access Publications

No abstract provided.

Q/R Site Interactions With The M3 Helix In Gluk2 Kainate Receptor Channels Revealed By Thermodynamic Mutant Cycles, Melany N. Lopez, Timothy J. Wilding, James E. Huettner

Open Access Publications

No abstract provided.