Digital Commons Network^™

Synthesis Of Tetrakis(Carboxyphenyl)Porphyrin Coated Paramagnetic Iron Oxide Nanoparticles Via Amino Acid For Photodegradation Of Methylene Blue, Rahmatollah Rahimi, Azadeh Tadjarodi, Mina Imani, Mahboubeh Rabbani, Samaneh Safalou Moghaddam, Hamed Kerdari

Turkish Journal of Chemistry

In this paper, synthesis of tetrakis(carboxyphenyl)porphyrin (TCPP) coated cadmium ferrite (CdFe_2O_4) nanoparticles by using L-lysine as an anchor is reported for the first time. The ferrimagnetic CdFe_2O_4 nanoparticles were prepared via the facile self-assembly method of reflux followed by a heating treatment. The obtained magnetic nanoparticles were coated with TCPP in the presence of the amino acid L-lysine by sonication in ethanol and then refluxing for 12 h. The structural characteristics of the products were determined using FT-IR and XRD pattern. Scanning electron microscopy (SEM) images indicated uniform morphologies of the magnetic nanoparticles with an average size of 43 nm. …

Sesquiterpene Hydrocarbons Of The Essential Oil Of Actinolema Macrolema Boiss, Betül Demi̇rci̇, Gülden Koltuksuz Yasdikcioğlu, Kemal Hüsnü Can Başer

Turkish Journal of Chemistry

The essential oils of Actinolema macrolema Boiss. (Apiaceae) were obtained by hydrodistillation in the first 3 (sample A) and the following 3 h (sample B) from crushed fruits and dried leaves (sample C), which were subsequently analyzed by GC and GC-MS. Overall, 64 components were characterized, representing 93% of the leaf oil. Thirty components were characterized from the fruit oil representing 95% of the first fraction and 90% of the second fraction consecutively. Guaia-5,7(11)-diene, selina-3,7(11)-diene, and juniper camphor were isolated from the oils by column chromatography and their structures were elucidated by GC-MS, ^1H NMR, and ^{13}C NMR. The occurrence …

Synthesis, Characterization, And Luminescence Of Zinc(Ii) And Cadmium(Ii) Coordination Complexes: [Zn(Phen)_2(Ch_3coo)](Clo_4), [Zn(Bpy)_2(Clo_4)](Clo_4), And [Cd(Phen)_2(No_3)_2], İbrahi̇m Kani̇, Mehmet Kurtça

Turkish Journal of Chemistry

Three metal complexes, [Zn(phen)_2(CH_3COO)](ClO_4) (1), [Zn(bpy)_2(ClO_4)](ClO_4) (2), and [Cd(phen)_2 (NO_3)_2] (3) (phen = 1,10-phenanthroline, bpy = 2,2 {Abedini, 2005 #222} -bipyridine), were synthesized and their structures were determined by single-crystal X-ray diffraction analyses. In 1, Zn(II) is coordinated by 4 nitrogen atoms from 2 phen molecules and 2 oxygen atoms from 1 acetato to form an octahedral configuration. In 2, Zn(II) has pentacoordination geometry with chelating 2 bpy and 1 perchlorato ion. In 3, phen and NO_3^- serve as bidentate ligands coordinating to Cd(II) through their nitrogen and oxygen atoms to form 8 coordination. Three-dimensional frameworks of complexes 1--3 are …

Simple And Convenient Preparation Of Novel 6,8-Disubstituted Quinoline Derivatives And Their Promising Anticancer Activities, Sali̇h Ökten, Osman Çakmak, Ramazan Erenler, Önem Yüce Şahi̇n, Şaban Teki̇n

Turkish Journal of Chemistry

A short and easy route is described for 6,8-disubstituted derivatives of quinoline and 1,2,3,4-tetrahydroquinoli- ne from 6,8-dibromoquinolines 2 and 7 by various substitution reactions. While copper-promoted substitution of 6,8-dibromide 2 produced monomethoxides 3 and 4, a prolonged reaction time mainly afforded dimethoxide 6 instead of 5, whose aromatization with DDQ and substitution reaction of dibromide 7 with NaOMe in the presence of CuI also gave rise to dimethoxide 6. Several 6,8-disubstituted quinolines were obtained by treatment of 6,8-dibromoquinoline (7) with n-BuLi followed by trapping with an electrophile [Si(Me)_3Cl, S_2(Me)_2, and DMF]. Furthermore, 7 was also converted to mono and dicyano …

Therapies For Neovascular Age-Related Macular Degeneration: Current Approaches And Pharmacologic Agents In Development., Mostafa Hanout, Daniel Ferraz, Mehreen Ansari, Natasha Maqsood, Saleema Kherani, Yasir J. Sepah, Nithya Rajagopalan, Mohamed Ibrahim, Diana V. Do, Quan Dong Nguyen

Journal Articles: Ophthalmology

As one of the leading causes of blindness, age-related macular degeneration (AMD) has remained at the epicenter of clinical research in ophthalmology. During the past decade, focus of researchers has ranged from understanding the role of vascular endothelial growth factor (VEGF) in the angiogenic cascades to developing new therapies for retinal vascular diseases. Anti-VEGF agents such as ranibizumab and aflibercept are becoming increasingly well-established therapies and have replaced earlier approaches such as laser photocoagulation or photodynamic therapy. Many other new therapeutic agents, which are in the early phase clinical trials, have shown promising results. The purpose of this paper is …

Vascular Disrupting Agent For Neovascular Age Related Macular Degeneration: A Pilot Study Of The Safety And Efficacy Of Intravenous Combretastatin A-4 Phosphate, Mohamed A. Ibrahim, Diana V. Do, Yasir J. Sepah, Syed M. Shah, Elizabeth Van Anden, Gulnar Hafiz, J. Kevin Donahue, Richard Rivers, Jai Balkissoon, James T. Handa, Peter A. Campochiaro, Quan Dong Nguyen

Journal Articles: Ophthalmology

BACKGROUND:

This study was designed to assess the safety, tolerability, and efficacy of intravenous infusion of CA4P in patients with neovascular age-related macular degeneration (AMD).

METHODS:

Prospective, interventional, dose-escalation clinical trial. Eight patients with neovascular AMD refractory to at least 2 sessions of photodynamic therapy received CA4P at a dose of 27 or 36 mg/m2 as weekly intravenous infusion for 4 consecutive weeks. Safety was monitored by vital signs, ocular and physical examinations, electrocardiogram, routine laboratory tests, and collection of adverse events. Efficacy was assessed using retinal fluorescein angiography, optical coherence tomography, and best corrected visual acuity (BCVA).

RESULTS:

The …

Comparing Biocompatibility Of Nanocrystalline Titanium And Titanium-Oxide With Microcrystalline Titanium, Raheleh Miralami, Laura Koepsell, Thyagaseely Sheela Premaraj, Bongok Kim, Geoffrey M. Thiele, J. Graham Sharp, Kevin L. Garvin, Fereydoon Namavar

Posters and Presentations: Orthopaedic Surgery & Rehab

No abstract provided.

Experiences Of Kenyan Healthcare Workers Providing Services To Men Who Have Sex With Men: Qualitative Findings From A Sensitivity Training Programme, Elise M. Van Der Elst, Evans Gichuru, Anisa Omar, Jennifer Kanungi, Zoe Duby, Miriam Midoun, Sylvia Shangani, Susan M. Graham, Adrian D. Smith, Eduard J. Sanders, Don Operario

Community & Environmental Health Faculty Publications

Introduction

Men who have sex with men (MSM) in Kenya are at high risk for HIV and may experience prejudiced treatment in health settings due to stigma. An on-line computer-facilitated MSM sensitivity programme was conducted to educate healthcare workers (HCWs) about the health issues and needs of MSM patients.

Methods

Seventy-four HCWs from 49 ART-providing health facilities in the Kenyan Coast were recruited through purposive sampling to undergo a two-day MSM sensitivity training. We conducted eight focus group discussions (FGDs) with programme participants prior to and three months after completing the training programme. Discussions aimed to characterize HCWs’ challenges in …

South Dakota State University Undergraduate General Catalog 2013-2014, South Dakota State University

South Dakota State University Catalogs and Bulletins: 1935 to present

No abstract provided.

Over The Borderline-A Review Of Margaret Price's Mad At School: Rhetorics Of Mental Disability And Academic Life, Gregory M. Duhl

Faculty Scholarship

This Article is about “madness” in higher education. In Mad at School: Rhetorics of Mental Disability and Academic Life, Professor Margaret Price analyzes the rhetoric and discourse surrounding mental disabilities in academia. In this Article, I place Price’s work in a legal context, discussing why the Americans with Disabilities Act fails those with mental illness and why reform is needed to protect them. My own narrative as a law professor with Borderline Personality Disorder frames my critique. Narratives of mental illness are important because they help connect those who are often stigmatized and isolated due to mental illness and provide …

International Law In The Anthropocene: Responding To The Geoengineering Challenge, Karen N. Scott

Michigan Journal of International Law

From The Odyssey to The Tempest and beyond, the control and deliberate manipulation of the weather constitutes an enduring and universal theme in myth and literature. In the twenty-first century, it is scientists and engineers rather than authors and artists who dream of weather and climate control, and their story, as described by James Rodger Fleming, "is not, in essence, a heroic saga about new scientific discoveries that can save the planet, as many of the participants claim, but a tragicomedy of overreaching, hubris, and self-delusion." This notwithstanding, the argument that we should deliberately manipulate earth systems and natural processes …

College Of Education And Human Services 2012-2013 Annual Report, College Of Education And Human Services, Wright State University

College of Education and Human Services Annual Reports

This annual report by the Wright State University College of Education and Human Services details the news and events of CEHS's organizations and departments in the 2012-2013 school year.

On Identifying And Analyzing Significant Nodes In Protein-­Protein Interaction Networks, Rohan Khazanchi, Kathryn Dempsey Cooper, Ishwor Thapa, Hesham Ali

Interdisciplinary Informatics Faculty Proceedings & Presentations

Network theory has been used for modeling biological data as well as social networks, transportation logistics, business transcripts, and many other types of data sets. Identifying important features/parts of these networks for a multitude of applications is becoming increasingly significant as the need for big data analysis techniques grows. When analyzing a network of protein-protein interactions (PPIs), identifying nodes of significant importance can direct the user toward biologically relevant network features. In this work, we propose that a node of structural importance in a network model can correspond to a biologically vital or significant property. This relationship between topological and …

On Mining Biological Signals Using Correlation Networks, Kathryn Dempsey Cooper, Ishwor Thapa, Claudia Cortes, Zack Eriksen, Dhundy Raj Bastola, Hesham Ali

Interdisciplinary Informatics Faculty Proceedings & Presentations

Correlation networks have been used in biological networks to analyze and model high-throughput biological data, such as gene expression from microarray or RNA-seq assays. Typically in biological network modeling, structures can be mined from these networks that represent biological functions; for example, a cluster of proteins in an interactome can represent a protein complex. In correlation networks built from high-throughput gene expression data, it has often been speculated or even assumed that clusters represent sets of genes that are coregulated. This research aims to validate this concept using network systems biology and data mining by identification of correlation network clusters …

Identifying Pathway Proteins In Networks Using Convergence, Kathryn Dempsey Cooper, Hesham Ali

Interdisciplinary Informatics Faculty Proceedings & Presentations

One of the key goals of systems biology concerns the analysis of experimental biological data available to the scientific public. New technologies are rapidly developed to observe and report whole-scale biological phenomena; however, few methods exist with the ability to produce specific, testable hypotheses from this noisy ‘big’ data. In this work, we propose an approach that combines the power of data-driven network theory along with knowledge-based ontology to tackle this problem. Network models are especially powerful due to their ability to display elements of interest and their relationships as internetwork structures. Additionally, ontological data actually supplements the confidence of …

The Honors Beacon, Issue 05, Winter 2013, Honors Program At Minnesota State University, Mankato

Honors Beacon

Winter 2013 newsletter of the Honors Program at Minnesota State University, Mankato.

Undergraduate And Graduate Course Descriptions, 2013 Spring, Wright State University

Course Descriptions

Wright State University undergraduate and graduate course descriptions from Spring 2013.

Portland State Magazine, Portland State University. Office Of University Communications

Portland State Magazine

PSU’s alumni magazine, published 2-3 times a year. In this issue: Travis Knight ’98 leads the enchantment at the Laika animation studio in Hillsboro; The University’s film program attracts the next generation of cinematographers; designing better portable classrooms; is Portlandia really Portland?: American Indians are bringing Native teaching practices into their classrooms; and more.

Developing And Assessing Curriculum On The Physics Of Medical Instruments, Warren Christensen, James K. Johnson, Grace R. Van Ness, Elliot E. Mylott, Justin C. Dunlap, Elizabeth A. Anderson, Ralf Widenhorn

Physics Faculty Publications and Presentations

Undergraduate educational settings often struggle to provide students with authentic biologically or medically relevant situations and problems that simultaneously improve their understanding of physics. Through exercises and laboratory activities developed in an elective Physics in Biomedicine course for upper-level biology or pre–health majors at Portland State University, we aim to teach fundamental physical concepts, such as light absorption and emission and atomic energy levels, through analysis of biological systems and medical devices. The activities address the properties of electromagnetic waves as they relate to the interaction with biological tissue and make links between physics and biomedical applications such as microscopy …

Liability Of Child Soldiers Under International Criminal Law, Fanny Leveau

Osgoode Hall Review of Law and Policy

The phenomenon of child soldiers has gained increased attention since the condemnation, last year, of Thomas Lubanga for recruiting and using child soldiers. However, not much has been said about the crimes perpetrated by those children. This article looks at child soldiers as perpetrators of crimes and examines their potential criminal accountability under international criminal law. Interpretation of international instruments suggests that child soldiers could be prosecuted by international criminal tribunals. However, those prosecutions would have to respect specific standards.

Faculty Senate Monthly Packet January 2013, Portland State University Faculty Senate

Faculty Senate Monthly Packets

The January 2013 Monthly packet includes the January agenda and appendices and the Faculty Senate minutes and attachments from the meeting held December 2012

On Measuring The Expertise Of Patent-Pilot Judges: Encouraging Enhancement Of Claim-Construction Uniformity, 12 J. Marshall Rev. Intell. Prop. L. 309 (2013), Etan S. Chatlynne

UIC Review of Intellectual Property Law

A Pilot Program to “encourage enhancement of expertise” in patent cases among district judges recently got underway in the federal courts. The program is designed to funnel patent cases to judges who volunteer to become “pilot judges.” The idea is that as these judges hear more patent cases and become more familiar with patent law, they will be able to craft claim constructions and opinions that are increasingly likely to survive the scrutiny of the Court of Appeals for the Federal Circuit. Unfortunately, the Federal Circuit’s jurisprudence may itself encumber these efforts because of a split among the Federal Circuit …

The Biosimilars Act: The United States’ Entry Into Regulating Biosimilars And Its Implications, 12 J. Marshall Rev. Intell. Prop. L. 322 (2013), Shawn P. Gorman, Adrian Pishko, John Iwanicki, Judith Stone-Hulslander

UIC Review of Intellectual Property Law

The Patient Protection and Affordable Care Act is most well-known for creating a mandate requiring individuals to have health insurance. However, another provision of the Act, the Biologics Price Competition and Innovation Act, created a new process for companies to introduce biosimilars, products that are highly similar to licensed drugs in terms of purity, safety, and potency, but have minor differences in the inactive ingredients. This provision seeks to alleviate strain on companies introducing biosimilars by creating an abbreviated pathway for their approval by the Food and Drug Administration, similar to an Abbreviated New Drug Application under the Hatch-Waxman Act. …

Reverse Payment Settlements: The U.S. Supreme Court Has Finally Agreed To Resolve The Issue, 12 J. Marshall Rev. Intell. Prop. L. 787 (2013), Tyler Cho

UIC Review of Intellectual Property Law

Paragraph IV of the Hatch-Waxman Act provides a mechanism for litigating pharmaceutical patent infringement disputes. Many of these cases have been settled with “reverse payments” from the brand to the generic in return for delayed generic entry. The U.S. Federal Trade Commission (FTC) has contested a number of these settlements with mixed results. On July 16, 2012, the U.S. Court of Appeals for the Third Circuit issued a decision holding that pharmaceutical patent settlements that restrict generic entry and contain a payment to the generic company are presumptively unlawful under U.S. antitrust laws. By holding that a patent settlement can …

Directed To Or Encompassing A Human Organism: How Section 33 Of The America Invents Act May Threaten The Future Of Biotechnology, 12 J. Marshall Rev. Intell. Prop. L. 768 (2013), Ava Caffarini

UIC Review of Intellectual Property Law

Biotechnology is a rapidly growing field that has pushed the limits of patent eligible subject matter. In response to the expansion of biotechnology, critics have emerged with both economic and moral concerns over the development and patenting of these technologies. On the economic front, critics are wary of the potential development of an“anticommons.” On the moral front, critics are concerned with the potential to erode human dignity and “play God.” Congress has responded to the moral concerns with section 33 of the America Invents Act. Section 33 states that“[n]otwithstanding any other provision of law, no patent may issue on a …

Application Of The Hatch-Waxman Act's Safe Harbor Provision Following Momenta, 13 J. Marshall Rev. Intell. Prop. L. 1 (2013), Alfred C. Server

UIC Review of Intellectual Property Law

The Federal Circuit’s recent decision in Momenta v. Amphastar highlights the continuing uncertainty regarding the scope of the statutory exemption from patent infringement provided in 35 U.S.C. § 271(e)(1). The statute states that “[i]t shall not be an act of infringement to make, use, offer to sell, or sell within the United States or import into the United States a patented invention . . . solely for uses reasonably related to the development and submission of information under a Federal law which regulates the manufacture, use, or sale of drugs or veterinary biological products.” Since its adoption in 1984 with …

Memetic Theory, Trademarks & The Viral Meme Mark, 13 J. Marshall Rev. Intell. Prop. L. 96 (2013), Shontavia Jackson Johnson

UIC Review of Intellectual Property Law

This Article proposes that memetic theory is a useful lens through which to view trademarks, particularly as there has been a rise in the number of applications for culturally-driven words and catchphrases in the United States Patent and Trademark Office. Memetic theory, or memetics, is a scientific field related to how units of information evolve and replicate. These units of information, called memes, undergo a process of natural selection comparable to that of genes. To survive as trademarks, memes must not only exist in the proper form, but they must also subsist in an environment where replication, variation, and selection …

The Effects Of Plainchant On Subjective Measures Of Emotion And Heart Rate Variance, Alexander J. Twohy

Honors Theses, 1963-2015

This study looked at the how plainchant affects the body on a physiological and emotional level. The study took the clinical findings of Sister Ruth Stanley (that chant has a relaxing effect in terms of heart rate variance) and attempted to replicate these results in an experimental setting. The design utilized heart rate variance, along with subjective measures of emotion, to help determine whether chant was an empirically viable candidate for music theapy. Emotional responses were divided into four quadrants based on the valence/arousal model of emotion. 29 participants were exposed to chant along with four samples of music chosen …

Teaching Our Faculty: Developing Copyright And Scholarly Communication Outreach Programs, Jennifer Duncan, Susanne K. Clement, Betty Rozum

Library Faculty & Staff Publications

No abstract provided.

Narratives Of Southern Contact Zones: Mobility And The Literary Imagination Of Zora Neale Hurston And Marjorie Kinnan Rawlings, Kyoko Shoji Hearn

Electronic Theses and Dissertations

This dissertation examines the literary works of the two Southern women writers, Zora Neale Hurston and Marjorie Kinnan Rawlings, based on the cultural contexts of the 1930s and the 1940s. It discusses how the two writers' works are in dialogue with each other, and with the particular historical period in which the South had gone through many social, economical, and cultural changes. Hurston and Rawlings, who became friends with each other beyond their racial background in the segregated South, shared physical and social mobility and the interest in the Southern folk cultures. They wrote fiction about the region and its …