Digital Commons Network^™

Recruitment Of The Intracellular Ca2+ By Ultrashort Electric Stimuli: The Impact Of Pulse Duration, Iurii Semenov, Shu Xiao, Olga N. Pakhomova, Andrei G. Pakhomov

Bioelectrics Publications

Nanosecond-duration electric stimuli are distinguished by the ability to permeabilize intracellular membranes and recruit Ca²⁺ from intracellular stores. We quantified this effect in non-excitable cells (CHO) using ratiometric Ca²⁺ imaging with Fura-2. In a Ca²⁺-free medium, 10-, 60-, and 300-ns stimuli evoked Ca2⁺ transients by mobilization of Ca²⁺ from the endoplasmic reticulum. With 2 mM external Ca²⁺, the transients included both extra- and intracellular components. The recruitment of intracellular Ca²⁺ increased as the stimulus duration decreased. At the threshold of 200–300 nM, the transients were amplified by calcium-induced calcium release. We …

The Upside Of Dissent In Equality Jurisprudence, Carissima Mathen

The Supreme Court Law Review: Osgoode’s Annual Constitutional Cases Conference

It is impossible to imagine constitutional law without dissent. Powerful and evocative, judicial dissent suggests roads not taken and points up law’s fundamental contingency. Though often criticized, dissent has numerous positive aspects. This paper considers a benefit of dissent that is borne out by equality cases. The paper first outlines two categories of dissent and, second, canvasses section 15, including a detailed discussion of a recent, sharply divided Supreme Court decision. The paper suggests that dissents are associated with richer, more complex accounts of equality. Borrowing the language of Sunstein, the paper proposes that a divided decision that is the …

Collapsing Suspect Class With Suspect Classification: Why Strict Scrutiny Is Too Strict And Maybe Not Strict Enough, Sonu Bedi

Georgia Law Review

While scholarly work often analyzes the nature and scope
of the Court's tiers of scrutiny approach to enforcing
equality, this Article examines the underlying theory of
equal protection. This Article mounts a challenge to the
theory of higher scrutiny, and, in particular,strict scrutiny.
It seeks to analyze two questions: (1) What principles trigger
heightened scrutiny? and (2) Why does the Court need to
subject laws that discriminate on the basis of race to strict
scrutiny? The first question concerns the underlying theory
of equal protection doctrine: the "what" of higher scrutiny.
Scholarly work that seeks to answer this question rightly …

Genetic Privacy & The Fourth Amendment: Unregulated Surreptitious Dna Harvesting, Albert E. Scherr

Georgia Law Review

Genetic privacy and police practices have come to the
fore in the criminal justice system. Case law and stories
in the media document that police are surreptitiously
harvesting the out-of-body DNA of putative suspects.
Some sources even indicate that surreptitious data
banking may also be in its infancy. Surreptitious
harvesting of out-of-body DNA by the police is currently
unregulated by the Fourth Amendment. The few courts
that have addressed the issue find that the police are free
to harvest DNA abandoned by a putative suspect in a
public place. Little in the nascent surreptitious harvesting
case law suggests that surreptitious …

Csbs Statements, V15, 2013, University Of Northern Iowa. College Of Social And Behavioral Sciences.

CSBS Statements

Contents:

-- From the Desk of the Dean
-- Stephen Quirk
-- CSBS faculty provides social science research support to YESS
-- CSBS alumna served as YESS intern and found her place
-- Quirk family leaves legacy in CSBS
-- A Young Hopeful
-- "We need to take care of each other."
-- From our Director of Development
-- The Dean's Fund for Excellence
-- College of Social & Behavioral Sciences Loyalty Roster
-- Dean's Fund Inner Circle
-- 2013 Distinguished Alumni Day
-- Center for Violence Prevention
-- Center for Social & Behavioral Research
-- GeoTREE Center
-- New …

Hydrologic Conditions And Streamflow Change In An Evolving Semi-Arid Agricultural Watershed, Smith River, Montana, Andrea Stanley

Graduate Student Theses, Dissertations, & Professional Papers

Agricultural land and water use has modified natural flow regimes in the western US. Understanding the effect of agricultural water use on streamflow is critical to effective water management and is often limited by the available data record. This investigation evaluates agricultural water use and streamflow in the Smith River watershed (SRW), a semi-arid agricultural watershed located on the eastern slope of the northern Rocky Mountains in west-central Montana. Questions motivating this study include: (1) Has agricultural water use modified streamflow on the Smith River? (2) What aspect of agricultural activity in the Smith River watershed is having the greatest …

Spatial Distribution And Quantification Of Forest Treatment Residues For Bioenergy Production, Lucas A. Wells

Graduate Student Theses, Dissertations, & Professional Papers

The availability and spatial distribution of forest treatment residues are prerequisites to supply chain development for bioenergy production. To accurately estimate potential residue quantities, data must be provided to simulate stand-level silviculture across the landscape of interest. However, biomass utilization assessments often consider broad regions where adequate data are not supplied. At present, these measures are addressed using strategic level assessments and broad-based management that may not be applicable to all areas of the landscape. This thesis introduces a new methodology for spatially describing stand-level treatment residue quantities based on detailed silvicultural prescriptions and site specific management. Using National Agricultural …

Ida Pfeiffer In China: Examining The Suppression Of Gender Roles In The Face Of European Colonial Superiority, Alec Down

Library Research Grants

No abstract provided.

A Comparative Study Of The Dry And Wet Nano-Scale Electro-Machining, M. P. Jahan, K. R. Virwani, Kamlakar P. Rajurkar, A. P. Malshe

Department of Mechanical and Materials Engineering: Faculty Publications

In recent years, a nano-electromachining (nano-EM) process based on a scanning tunneling microscope (STM) platform has been demonstrated. Nano-EM is capable of machining nano-features, under both, liquid dielectric (wet nano-EM) and air dielectric (dry nano-EM) media. The objective of this paper is to present a comparative study between the wet and dry nano-EM processes based on process mechanism, machining performance, consistency and dimensional repeatability of these two processes. The comparison of the two processes has been conducted at near field nano-EM, where the gap between the tool electrode and workpiece is 2 nm and the machining is performed at room …

Systems Biology Of The Functional And Dysfunctional Endothelium, Jennifer Frueh, Nataly Maimari, Takayuki Homma, Sandra M. Bovens, Ryan M. Pedrigi, Leila Towhidi, Rob Krams

Department of Mechanical and Materials Engineering: Faculty Publications

This review provides an overview of the effect of blood flow on endothelial cell (EC) signalling pathways, applying microarray technologies to cultured cells, and in vivo studies of normal and atherosclerotic animals. It is found that in cultured ECs, 5–10% of genes are up- or down-regulated in response to fluid flow, whereas only 3–6% of genes are regulated by varying levels of fluid flow. Of all genes, 90%are regulated by the steady part of fluid flow and 10% by pulsatile components. The associated gene profiles show high variability from experiment to experiment depending on experimental conditions, and importantly, the bioinformatical …

Efficacy Of Foliar Fungicides And Application Timing Of Stratego Yld On Field Corn In Nebraska, 2013, C. M. Schleicher, T. A. Jackson-Ziems

Department of Plant Pathology: Faculty Publications

A foliar fungicide efficacy timing trial was conducted at the University of Nebraska-Lincoln South Central Agricultural Laboratory near Clay Center, NE. Corn hybrid NK ‘N68B’, rating of “fair” (7 out of 9) for gray leaf spot (GLS), not rated for common rust (CR), and “excellent” (2 out of 9) for southern rust (SR), was planted on 15 May in 30-in. rows at a target population of 31,763 plants/A. The trial area was disked with corn as the previous year’s crop. Nine treatments and a nontreated control were replicated six times in a randomized complete block design. Each plot was four …

Evaluation Of Foliar Fungicide And Application Timing On Field Corn Following Hail Event At Scal In Nebraska, 2013, C. M. Schleicher, T. A. Jackson-Ziems

Department of Plant Pathology: Faculty Publications

A foliar fungicide efficacy timing trial was conducted at the University of Nebraska-Lincoln South Central Agricultural Laboratory near Clay Center, NE to determine the potential effect of foliar fungicides and their application timing on lodging and yield after a late season hail event. Novartis corn hybrid N6800 GT with CruiserMaxx 250 seed treatment was planted on 24 May in 30 in. rows with a target population of 32,000 plants/A. Force 3G (4 oz/1,000 row ft) was applied in-furrow at planting. Lexar (3 qt/A) + Roundup UltraMax (32 fl oz/A) was applied on 5 Jun. The trial area had corn as …

Efficacy Evaluation Of Fortix And Headline Amp Application Timing In Field Corn In Nebraska, 2013, C. M. Schleicher, T. A. Jackson-Ziems

Department of Plant Pathology: Faculty Publications

A foliar fungicide efficacy timing trial was conducted at the University of Nebraska-Lincoln South Central Agricultural Laboratory near Clay Center, NE. Corn hybrid NK ‘N68B’, rating of “fair” (7 out of 9) for gray leaf spot (GLS), not rated for common rust (CR), and “excellent” (2 out of 9) for southern rust (SR), was planted on 15 May in 30-in. rows at a target population of 31,763 plants/A. The trial area was disked with corn as the previous year’s crop. Nine treatments were replicated six times in a randomized complete block design. Each plot was four rows (10 ft) wide …

Efficacy Evaluation Of Foliar Fungicide Application Timing In Field Corn In Nebraska, 2012, C. M. Schleicher, T. A. Jackson-Ziems

Department of Plant Pathology: Faculty Publications

A foliar fungicide efficacy trial was conducted at the University of Nebraska-Lincoln South Central Agricultural Laboratory near Clay Center, NE. DeKalb corn hybrid DKC 64-83, rating of “good” (6 out of 9) for gray leaf spot (GLS), “very good” (4 out of 9) for common rust (CR), and “good” (5 out of 9) for southern rust (SR), was planted on 26 Apr in 30-in. rows at a target population of 30,600 plants/A. The trial area was disked with corn as the previous year’s crop. Six foliar fungicide treatments and a non-treated control were replicated six times in a randomized complete …

What’S New In Plant Pathology, Loren Giesler, Tamra A. Jackson-Ziems, Casey Schleicher, Kevin Korus

Department of Plant Pathology: Faculty Publications

Extension Plant Pathology Team Update

Plant and Pest Diagnostic Clinic Update

Disease Management Products

Table 1. Foliar Fungicide Label Updates

Table 2. New Products

Impacts Of Drought On Disease Development And Management, Stephen Wegulo, Loren Giesler, Robert Harveson, Tamra A. Jackson-Ziems, Bo Liu, Kevin Korus

Department of Plant Pathology: Faculty Publications

Drought conditions such as those that occurred in Nebraska in 2012 can impact the development of plant diseases. In general drought slows down or prevents the development of plant diseases caused by pathogens that thrive under moist conditions. However, some diseases are favored by drought. This is because when plants are stressed due to lack of moisture or excessive heat, they become more susceptible to these diseases. This article presents examples of diseases of agronomic crops favored by drought and how to manage them. Data are provided on the effect of dry or wet conditions on the profitability of applying …

Grain Storage Management To Minimize Mold And Mycotoxins, Thomas W. Dorn, Tamra A. Jackson-Ziems

Department of Plant Pathology: Faculty Publications

As most dryland corn producers are aware, the dry and hot growing season in 2012 resulted in reduced corn yields with moderately lower test weights. Along with the reduced test weights are concerns about potential mycotoxin contamination in the drought-stressed grain.

The only way to know for sure if there are mycotoxins in your grain and which specific mycotoxins are present is to collect representative grain samples and have them tested by a certified laboratory.

Many species of fungi can cause ear rot diseases and molding of grain. Most of these fungi become associated with the grain in the field …

Institutional Assessment Report, 2013, University Of Montana--Missoula. Office Of The Provost

University of Montana Planning and Assessment Reports, 1969-2016

The University of Montana 2013 Institutional Assessment Report, issued by the Office of the Provost.

Nine Simple Ways To Make It Easier To (Re)Use Your Data, Ethan White, Elita Baldridge, Zachary Brym, Kenneth Locey, Daniel Mcglinn

Faculty Publications

No abstract provided.

Challenges Of Unconventional Shale Gas Development: So What's The Rush, Bernard D. Goldstein, Elizabeth Ferrell Bjerke, Jill Kriesky

Notre Dame Journal of Law, Ethics & Public Policy

No abstract provided.

Mushroom Ganoderma Lucidum Prevents Colitis- Associated Carcinogenesis In Mice, Daniel Sliva, Jagadish Loganathan, Jiahua Jiang, Andrej Jedinak, John G. Lamb, Colin Terry, Lee Ann Baldridge, Jiri Adamec, George E. Sandusky, Shailesh Dudhgaonkar

Department of Biochemistry: Faculty Publications

Background: Epidemiological studies suggest that mushroom intake is inversely correlated with gastric, gastrointestinal and breast cancers. We have recently demonstrated anticancer and anti-inflammatory activity of triterpene extract isolated from mushroom Ganoderma lucidum (GLT). The aim of the present study was to evaluate whether GLT prevents colitis-associated carcinogenesis in mice.

Methods/Principal Findings: Colon carcinogenesis was induced by the food-borne carcinogen (2-Amino-1-methyl-6- phenylimidazol[4,5-b]pyridine [PhIP]) and inflammation (dextran sodium sulfate [DSS]) in mice. Mice were treated with 0, 100, 300 and 500 mg GLT/kg of body weight 3 times per week for 4 months. Cell proliferation, expression of cyclin D1 and COX-2 and …

The Hyaluronan Receptor For Endocytosis (Hare) Activates Nf-Κb-Mediated Gene Expression In Response To 40–400-Kda, But Not Smaller Or Larger, Hyaluronans, Madhu S. Pandey, Bruce A. Baggenstoss, Jennifer Washburn, Edward N. Harris, Paul H. Weigel

Department of Biochemistry: Faculty Publications

Background: HARE mediates systemic clearance of hyaluronan (HA), which turns over continuously in tissues.

Results: HARE uptake of 40–400-kDa, but not larger or smaller, HA stimulated NF-κB activation.

Conclusion: HA-HARE signal complexes activate NF-κB and gene transcription only with optimally sized HA.

Significance: HARE responsiveness to a narrow size range ofHAdegradation products may be a sensing system to detect tissue ECM stress.

A Virus-Encoded Potassium Ion Channel Is A Structural Protein In The Chlorovirus Paramecium Bursaria Chlorella Virus 1 Virion, Giulia Romani, Adrianna Piotrowski, Stefan Hillmer, James Gurnon, James L. Van Etten, Anna Morani, Gerhard Thiel, Brigitte Hertel

James Van Etten Publications

Most chloroviruses encode small K+ channels, which are functional in electrophysiological assays. The experimental finding that initial steps in viral infection exhibit the same sensitivity to channel inhibitors as the viral K+ channels has led to the hypothesis that the channels are structural proteins located in the internal membrane of the virus particles. This hypothesis was questioned recently because proteomic studies failed to detect the channel protein in virions of the prototype chlorovirus Paramecium bursaria chlorella virus 1 (PBCV-1). Here, we used a mAb raised against the functional K+ channel from chlorovirus MA-1D to search for the viral K+ channel …

Potassium Ion Channels: Could They Have Evolved From Viruses?1[W], Gerhard Thiel, Anna Moroni, Guillaume Blanc, James L. Van Etten

James Van Etten Publications

Cells communicate among themselves by electrical activity. Sophisticated membrane-embedded proteins, called ion channels, catalyze rapid, selective, and regulated ion fluxes across membranes (Hille, 2001). The resulting membrane currents are responsible for neuronal activity and the systemic propagation of electrical signals in animals. The activity of some channels is important for muscle movement in animals or growth in plants; other channels sense the concentration of physiological signals and modulate key processes in all kinds of eukaryotic cells. Among the many diverse ion channels in higher organisms, K+ channels are among the most important. One feature of K+ channels is that they …

Forestry Kaimin, 2012-2013, University Of Montana--Missoula. College Of Forestry And Conservation. Forestry Club

Forestry Kaimin, 1915-2015

Annual yearbook of the University of Montana’s Forestry Student Association (Forestry Club).

Degradable Plastics And Solid Waste Management Systems, David J. Tonjes, Krista L. Thyberg

Technology & Society Faculty Publications

Plastics, which are woven into the fabric of modern life, have consequential impacts on the environment. Many of these are associated with end-of-lifetime processes, and include chemical contamination of the environment and effects from litter. Plastics also complicate waste management processes, causing contamination in composting operations, and having poor recovery rates through recycling. Plastics that are not as biologically recalcitrant, that decompose when use is done, have been perceived as solutions to at least some of these problems. The first generation of degradable plastics did not meet marketing claims; some of the more recent formulations, partly as a consequence of …

A Classification Methodology For Landfill Leachates, David J. Tonjes

Technology & Society Faculty Publications

A characterization scheme based on landfill leachate chemical signatures could support studies of leachate evolution over time, liner performance, and help confirm or disprove potential leachate contamination of groundwater. Wide variations in single constituents across time, sites, and site practices, and inconsistencies related to common bivariate measures suggest a robust, multivariate analysis could be useful. A variant Stiff diagram approach (a subjective analytical comparison of soluble salts) has been developed, and supports graphical depictions of multiple samples. The hypothesis is that leachates with similar chemistry form clusters, and this was tested using a data set of 652 samples from 26 …

Assessment Of Seagrass Floral Community Structure From Two Caribbean Marine Protected Areas, Paul Bologna, Anthony John Suleski

Department of Biology Faculty Scholarship and Creative Works

Seagrass communities represent spatially complex and biomass producing systems comprised of intermixed seagrass and algal species. We investigated shallow water communities from two Marine Protected Areas (MPAs) in the Caribbean: St. John, United States Virgin Islands and Cayos Cochinos, Honduras. St. John sites (4) lie within the Virgin Islands National Park and the Coral Reef National Monument and are designated within an UNESCO Biosphere Reserve. Honduran sites (4) lie within the designated Marine National Monument. Our results indicate that both MPAs were dominated by Thalassia testudinum with spatial coverage and shoot density significantly greater in Honduras. Many sites also showed …

Revisiting The Presumption Of Jointly Placing Siblings In Foster Care, Karen Rothschild, Daniel Pollack

Seattle Journal for Social Justice

No abstract provided.

Volume 7, 2013, Csusb

Scholarship in Action newsletter

What to look for in this issue...

• Faculty Research
  • Carolyn Eggleston p.1
  • Submission Success Rates- CSUSB Faculty Rock! p.9
• Awards p.4
• Grant Writers' Workshop Coming in June p.6
• Did you Know? p.6
• Presentations, Publications, Exhibitons and Performances p.7
• SCORE More with NIH p.12
• Helpful Hints p.13
• Contact Information p.13