Digital Commons Network^™

Using Operant Conditioning To Train Cervus Canadensis, Jonathan Larson

Biology Posters

No abstract provided.

Sources Of Uncertainty In Nutrient Sampling Below A Point Source, Hayden Campbell

Biology Posters

No abstract provided.

Predicting Natural Base-Flow Stream Water Chemistry In The Western United States, J. R. Olson, Charles P. Hawkins, D. M. Carlisle

Watershed Sciences Faculty Publications

[1] Robust predictions of stream solute concentrations expected under natural (reference) conditions would help establish more realistic water quality standards and improve stream ecological assessments. Models predicting solute concentrations from environmental factors would also help identify the relative importance of different factors that influence water chemistry. Although data are available describing the major factors controlling water chemistry (i.e., geology, climate, atmospheric deposition, soils, vegetation, topography), geologic maps do not adequately convey how rocks vary in their chemical and physical properties. We addressed this issue by associating rock chemical and physical properties with geological map units to produce continuous maps of …

A Networks Method For Ranking Microrna Dysregulation In Cancer, William Budd, Sarah Seashols, Danielle Weaver, Cyriac Joseph, Zendra E. Zehner

Biochemistry and Molecular Biology Publications

Background

Despite the lack of agreement on their exact roles, it is known that miRNAs contribute to cancer progression. Many studies utilize methods to detect differential regulation of miRNA expression. It is prohibitively expensive to examine all potentially dysregulated miRNAs and traditionally, researchers have focused their efforts on the most extremely dysregulated miRNAs. These methods may overlook the contribution of less differentially expressed but more functionally relevant miRNAs. The purpose of this study was to outline a method that not only utilizes differential expression but ranks miRNAs based on the functional relevance of their targets. This work uses a networks …

Estimation Of Cpg Coverage In Whole Methylome Next-Generation Sequencing Studies, Edwin Jcg Van Den Oord, Jozsef Bukszar, Gabor Rudolf, Srilaxmi Nerella, Joseph L. Mcclay, Lin Y. Xie, Karolina A. Aberg

Biomarker Research and Personalized Medicine Publications

Background

Methylation studies are a promising complement to genetic studies of DNA sequence. However, detailed prior biological knowledge is typically lacking, so methylome-wide association studies (MWAS) will be critical to detect disease relevant sites. A cost-effective approach involves the next-generation sequencing (NGS) of single-end libraries created from samples that are enriched for methylated DNA fragments. A limitation of single-end libraries is that the fragment size distribution is not observed. This hampers several aspects of the data analysis such as the calculation of enrichment measures that are based on the number of fragments covering the CpGs.

Results

We developed a non-parametric …

The Human Transformation Of Rapa Nui (Easter Island, Pacific Ocean), Terry L. Hunt, Carl P. Lipo

Anthropology Faculty Scholarship

Rapa Nui (Easter Island) has become widely known as a case study of human-induced environmental catastrophe resulting in cultural collapse. The island's alleged "ecocide" is offered as a cautionary tale of our own environmental recklessness. The actual archaeological and historical record for the island reveals that while biodiversity loss unfolded, the ancient Polynesians persisted and succeeded. Demographic "collapse" came with epidemics of Old World diseases introduced by European visitors. In this paper, we outline the process of prehistoric landscape transformation that took place on Rapa Nui. This process includes the role of humans using fire to remove forest and convert …

Icipe Demonstrating Excellence 2007-2012, International Centre Of Insect Physiology And Ecology (Icipe)

icipe Annual Reports

No abstract provided.

Volume 42 Number 1, Eiu College Of Education

Eastern Education Journal

No abstract provided.

History At Eiu (May 2013), History

History at Eastern

No abstract provided.

Exercise And Blood Flow Restriction, Zachary K. Pope, Jeffrey Willardson, Brad J. Schoenfeld

Faculty Research and Creative Activity

Pope, ZK, Willardson, JM, and Schoenfeld, BJ. Exercise and blood flow restriction. J Strength Cond Res 27(10): 2914– 2926, 2013—A growing body of research has demonstrated the effectiveness of exercise (low-intensity resistance training, walking, cycling) combined with blood flow restriction (BFR) for increased muscular strength and hypertrophy. The BFR is achieved via the application of external pressure over the proximal portion of the upper or lower extremities. The external pressure applied is sufficient to maintain arterial inflow while occluding venous outflow of blood distal to the occlusion site. With specific reference to low-intensity resistance training, the ability to significantly increase …

Examining The Causes Of Rarity For The Odonata Of Illinois, Miranda R. White, Paul V. Switzer

Faculty Research & Creative Activity

Odonata (dragonflies and damselflies) play an important role in habitat management and conservation, but our understanding of the causes of commonness versus rarity in this group is limited. In this study we examined the causes of rarity for the Odonata of Illinois. Using S-ratings for conservation status and published habitat classifications for Illinois odonates, we investigated whether habitat type (lotic versus lentic) or habitat specificity (whether they were limited to a specific type of aquatic habitat) was related to commonness. We found that lotic species and habitat specialists were more likely to be rare than lentic and generalist species. More …

Writing Center Annual Report, Tim Taylor

Criterion 3 Documents

No abstract provided.

A Spatially Explicit Model To Predict Radiocesium Body Burdens Of White- Tailed Deer On The U.S. Department Of Energy's Savannah River Site, Christopher W. Bobryk, Karen F. Gaines, James M. Novak, Susan A. Blas

Faculty Research & Creative Activity

We developed a spatially explicit exposure model to interpolate and predict radiocesium (137Cs) body burdens found in white-tailed deer (Odocoileus virginianus) on the U.S. Department of Energy’s (USDOE) Savannah River Site (SRS) to gain insight into and differentiate between the main contributing sources of this radionuclide for use in harvest management strategies that focus on minimizing human risk. Hunting has been allowed from permanent stands as a mechanism to manage the deer herd since 1965. All animals are monitored in the field for gross beta and gamma activity levels, providing a spatially explicit dataset. The models described here use the …

Fall 2013 Enrollment Tables, Planning & Institutional Studies

Criterion 1 Documents

No abstract provided.

2013-2014 Undergraduate Catalog, Eastern Illinois University

Primary Documents of Eastern Illinois University

No abstract provided.

2013 Career Services Annual Report, Career Services, Eiu

Criterion 4 Documents

No abstract provided.

Isoform-Specific Effects Of Apoe On Neurite Outgrowth In Olfactory Epithelium Culture, Aseem Hussain, Minh Luong, Apryl Pooley, Britto P. Nathan

Faculty Research & Creative Activity

The apolipoprotein E4 (apoE4) genotype is a major risk factor for developing late-onset Alzheimer’s disease (AD). Inheritance of apoE4 is also associated with impairments in olfactory function in early stages of AD. In this project we examined the effects of the three common isoforms of human apoE (apoE2, apoE3, and apoE4) on neuronal differentiation and neurite outgrowth in explant cultures of mouse olfactory epithelium (OE).

Diapause And Anhydrobiosis In Embryos Of Artemia Franciscana: Metabolic Depression, Lea Proteins And Water Stress, Steven C. Handel, Yuvraj Patil, Shumin Li, Nilay Chakraborty, Apurva Borcar, Michael A. Menze, Leaf C. Boswell, Daniel Moore, Mehmet Toner

Faculty Research & Creative Activity

Metabolic depression is typically correlated with extended survival of environmental challenge and energy-limitation in early life stages of various invertebrates and vertebrates. Diapause is an ontogenetically-programmed reduction of development and often metabolism seen in many invertebrates. When embryos of Artemia franciscana enter the state of diapause, the overall metabolic depression is estimated to be greater than 99%. These embryos also contain trehalose and express multiple isoforms of Late Embryogenesis Abundant (LEA) proteins, constituents often present in a number of such anhydrobiotic animals. The mRNA levels for LEA proteins are highest in diapause and post-diapause embryos that possess desiccation tolerance, but …

Phenotypic And Genotypic Characterization Of Escherichia Coli Isolated From Untreated Surface Waters, Kai F. Hung, Steven L. Daniel, Kristopher J. Janezic, Blake Ferry, Eric W. Hendricks, Brian A. Janiga, Tiffany Johnson, Samantha Murphy, Morgan E. Roberts, Sarah M. Scott, Alexandra N. Theisen

Faculty Research & Creative Activity

A common member of the intestinal microbiota in humans and animals is Escherichia coli. Based on the presence of virulence factors, E. coli can be potentially pathogenic. The focus of this study was to isolate E. coli from untreated surface waters (37 sites) in Illinois and Missouri and determine phenotypic and genotypic diversity among isolates. Water samples positive for fecal coliforms based on the Colisure® test were streaked directly onto Eosin Methylene Blue (EMB) agar (37°C) or transferred to EC broth (44.5°C). EC broth cultures producing gas were then streaked onto EMB agar. Forty-five isolates were identified as E. coli …

Comparative Anatomy And Dorsal Fin Muscle Activity During Turning Maneuvers In Two Shark Species, Anabela Maia, Cheryl Wilga

Faculty Research & Creative Activity

Stability and procured instability characterize two opposing types of swimming, steady and maneuvering, respectively. Fins can be used to manipulate flow to adjust stability during swimming maneuvers either actively using muscle control or passively by structural control. The function of the dorsal fins during turning maneuvering in two shark species with different swimming modes is investigated here using musculoskeletal anatomy and muscle function. White-spotted bamboo sharks are a benthic species that inhabits complex reef habitats and thus have high requirements for maneuverability. Spiny dogfish occupy a variety of coastal and continental shelf habitats and spend relatively more time cruising in …

Isoform-Specific Effects Of Apoe On Neurite Outgrowth In Olfactory Epithelium Culture, Aseem Hussain, Minh Luong, Apryl Pooley, Britto Nathan

Faculty Research & Creative Activity

The apolipoprotein E4 (apoE4) genotype is a major risk factor for developing late-onset Alzheimer’s disease (AD). Inheritance of apoE4 is also associated with impairments in olfactory function in early stages of AD. In this project we examined the effects of the three common isoforms of human apoE (apoE2, apoE3, and apoE4) on neuronal differentiation and neurite outgrowth in explant cultures of mouse olfactory epithelium (OE).

Examining The Causes Of Rarity For The Odonata Of Illinois, Miranda White, Paul Switzer

Faculty Research & Creative Activity

Odonata (dragonflies and damselflies) play an important role in habitat management and conservation, but our understanding of the causes of commonness versus rarity in this group is limited. In this study we examined the causes of rarity for the Odonata of Illinois. Using S-ratings for conservation status and published habitat classifications for Illinois odonates, we investigated whether habitat type (lotic versus lentic) or habitat specificity (whether they were limited to a specific type of aquatic habitat) was related to commonness. We found that lotic species and habitat specialists were more likely to be rare than lentic and generalist species. More …

The Role Of Men In Gender Equality: European Strategies & Insights: The Study Of The Role Of Men In Gender Equality, Niall Hanlon

Reports

No abstract provided.

Washington University In St. Louis Irb Meeting Guide, Human Research Protection Office, Washington University School Of Medicine In St. Louis

HRPO Publications

No abstract provided.

Generation And Characterization Of Peptide Fusion Proteins, Brianna L. Probasco

Graduate School of Biomedical Sciences Theses and Dissertations

Pathogenic Th17 cells drive progression of many autoimmune diseases. Th17 cells develop from naïve T cells in the immune system after antigen-driven stimulation in a specific cytokine environment. Normally, T cells act to fight off infection, but when not properly controlled, they can cause disease. The cytokine interleukin-23 (IL-23) plays an essential role in the expansion of pathogenic Th17 cells. IL-23 is a heterodimeric protein, composed of a p19 alpha chain and a p40 beta chain. The p40 is also part of IL-12 and binds to the IL-12 receptor beta 1 (IL-12Rβ1) subunit. Thus, it follows that the IL-23 receptor …

In-Service Teachers’ Understanding And Teaching Of Humane Education Before And After A Standards-Based Intervention, Stephanie Itle-Clark

The purpose of this study was to examine the ways in which credentialed educators conceptualized, understood, and perceived humane education, as well as their intent to include humane education in personal practice and their knowledge of strategies for integrating humane education concepts into their classroom work. The group of 25 educators participated in an online eight-week professional development course and completed pre- and post-surveys. The participants consisted of educators from the United States, British Columbia, and Vietnam. Participants were 11 secondary educators, 10 primary educators, 2 substitute teachers, 1 administrator, and 1 librarian. Results indicate that after an eight-week professional …

Explaining China’S Wildlife Crisis: Cultural Tradition Or Politics Of Development, Peter J. Li

Threatened and Endangered Animal Populations Collection

This chapter is about China’s wildlife crisis. As the following sections attempt to demonstrate, abuse of and assault on wildlife in captivity and in the wild have reached an unprecedented level on the Chinese mainland in the reform era (1978–present). Shocking brutality against wildlife animals has been frequently exposed by Chinese and international media. To readers outside East Asia, they ask if the Chinese are culturally indifferent to animal suffering. Indeed, does the Chinese culture sanction cruelty to animals? Or is it the contemporary politics of economic development that is more directly responsible for the crisis?

The Applicability Of The Self-Fulfillment Account Of Welfare To Nonhuman Animals, Babies, And Mentally Disabled Humans, Tatjana Visak, Jonathan Balcombe

Sentience Collection

In this paper we will argue that generality is a virtue of Haybron’s account of welfare. Indeed, reflecting on the applicability of his theory to nonhuman animals will give us a better understanding of its applicability to humans. We will first focus on self-fulfillment and suggest an interpretation of Haybron’s account according to which the self-fulfillment of an individual consists in the fulfillment of the aspects of the self that are applicable to that particular individual. This makes Haybron’s account of welfare applicable to all sentient beings. Then we will focus on sub-personal nature-fulfillment and argue that the same interpretation …

Prolonged Pain Research In Mice: Trends In Reference To The 3rs, Jonathan Balcombe, Hope Ferdowsian, Lauren Briese

Experimentation Collection

This literature review documents trends in the use of mice in prolonged pain research, defined herein as research that subjects mice to a source of pain for at least 14 days. The total amount of prolonged pain research on mice has increased dramatically in the past decade for the 3 pain categories examined: neuropathic, inflammatory, and chronic pain. There has also been a significant rise in the number of prolonged mouse pain studies as a proportion of all mouse studies and of all mouse pain studies. The use of transgenic mice has also risen significantly in prolonged pain research, though …

Environmental Impacts Of Puppy Mills, The Humane Society Of The United States

PUPPY MILL REPORTS

A puppy mill is “a dog breeding operation in which the health of the dogs is disregarded in order to maintain a low overhead and maximize profits.” Avenson v. Zegart, 577 F. Supp. 958, Dist. Court, Minnesota (1984). State and federal inspection reports reveal that a common method employed to maximize profits includes irresponsible waste management practices that are harmful to the environment. Impacts may be caused by improper disposal of feces, urine and carcasses.