Digital Commons Network^™

Rearrangement Of Cyclotriveratrylene (Ctv) Diketone: 9,10-Diarylanthracenes With Oled Applications, Samuel R. Sarsah, Marlon R. Lutz Jr., Matthias Zeller, David S. Crumrine, Daniel Becker

Chemistry: Faculty Publications and Other Works

Electroluminescent 9,10-diaryl anthracenes have been shown to be promising host and hole-transporting materials in organic electroluminescence due to their high thermal stability, electrochemical reversibility, and wide band gap useful for organic light-emitting diodes (OLEDs), especially blue OLEDs. Oxidation of cyclotriveratrylene (CTV) to the corresponding diketone and subsequent bromination resulted in an unexpected rearrangement to a highly functionalized 9-aryl-10-bromoanthracene derivative, which was employed in Suzuki couplings to synthesize a series of 9,10-diaryl compounds that are structural analogues of anthracene derivatives used in the preparation of OLEDs but are more highly functionalized, including electron-donating methoxy groups in addition to substitution by a …

Priority Interventions To Reduce Hiv Transmission In Sex Work Settings In Sub-Saharan Africa And Delivery Of These Services, Matthew F. Chersich, Stanley Luchters, Innocent Ntaganira, Antonio Gerbase, Ying-Ru Lo, Fiona Scorgie, Richard Steen

Population Health, East Africa

Introduction: Virtually no African country provides HIV prevention services in sex work settings with an adequate scale and intensity. Uncertainty remains about the optimal set of interventions and mode of delivery.

Methods: We systematically reviewed studies reporting interventions for reducing HIV transmission among female sex workers in sub-Saharan Africa between January 2000 and July 2011. Medline (PubMed) and non-indexed journals were searched for studies with quantitative study outcomes.

Results: We located 26 studies, including seven randomized trials. Evidence supports implementation of the following interventions to reduce unprotected sex among female sex workers: peer-mediated condom promotion, risk-reduction counselling and skills-building for …

Effectiveness Of A Community-Based Positive Prevention Intervention For People Living With Hiv Who Are Not Receiving Antiretroviral Treatment: A Prospective Cohort Study, Avina Sarna, Stanley Luchters, Eustasius Musenge, Jerry Okal, Matthew Chersich, Waimar Tun, Sabine Mall, Nzioki Kingola, Sam Kalibala

Population Health, East Africa

Background: We report effectiveness of an HIV-prevention intervention delivered by community health workers (CHWs) in Mombasa, Kenya, to PLHIV who have not initiated or who have discontinued ART-an often difficult-to-reach population because they fall outside the ambit of health care and prevention services.

Methods: A 2-arm cohort study assessed a structured risk-reduction intervention involving at least 4 one-to-one counseling sessions and personalized support. The control group received standard prevention services. CHWs recruited treatment-naïve people living with HIV (PLHIV) or those who had previously taken antiretroviral drugs. Data were analyzed using a Propensity Score Matched (PSM)-sample to control for baseline differences …

Report On The 2010 Rapid Assessment Survey Of Marine Species At New England Floating Docks And Rocky Shores., Christopher M. Mcintyre, Adrienne L. Pappal, Jessica Bryant, James T. Carlton, Kevin Cute, Jennifer A. Dijkstra, Renee Erickson, Yvette L. Garner, Arriaan Gittenberger, Sara P. Grady, Linsey Haram, Larry G. Harris, Niels-Viggo Hobbs, Charles C. Lambert, Gretchen Lambert, Walter J. Lambert, Antonio Carlos Marques, Arthur C. Mathieson, Megan Mcculler, Miranda Mickiewicz, Judith Pederson, Rachel Rock-Blake, Jan P. Smith, Cascade Sorte, Lauren Stefaniak, Martine Wagstaff

Center for Coastal and Ocean Mapping

No abstract provided.

The Effects Of Problem-Based Learning On Metacognitive Awareness And Attitudes Toward Chemistry Of Prospective Teachers With Different Academic Backgrounds, Cemal Tosun, Erdal Senocak

Australian Journal of Teacher Education

The aim of this study was to reveal the effects of Problem-based Learning (PBL) on the metacognitive awareness and attitudes toward chemistry of teacher candidates with different academic backgrounds. The study was carried out on one group using both pre- and post-test experimental studies. The findings of the study were obtained through quantitative approaches. The sample of the study was 70 first-year undergraduate students at a state university in Turkey taking General Chemistry/General Chemistry-II classes. The study was implemented during the spring semester of the 2011-2012 academic years and for a period of 20 hours. Quantitative data was obtained using …

Genomics And Autism Spectrum Disorder, Norah L. Johnson

College of Nursing Faculty Research and Publications

Purpose: To present the current state of the evidence regarding translation of genetics (the study of single genes) and genomics (the study of all genes and gene-gene or gene-environment interactions) into health care of children with autism spectrum disorder (ASD).

Methods: This article presents an overview of ASD as an international health challenge, the emerging science related to broad diagnostic criteria, and the role of the nurse in research, education, and practice.

Findings: Much progress is being made in the understanding of genetics and genomics of ASD. Environmental factors are thought to contribute to the risk of developing ASD by …

Cirt Newsletter--March 2013, Center For Instruction & Research Technology (Cirt)

CIRT News

This issue contains the following articles:

Faculty Spotlight: Using iMovie on the iPad for In- Class Video Production

Changing Course: Ten Years of Online Education

Upcoming Events

Digital Thinking: NMC Horizon Report: 2013 Higher Education Edition

Best Practices Online: Lectures Using Blackboard Collaborate

Blackboard News: May Upgrade & New Video Tool

App Review: CloudOn

News from ITS: Kivuto

New in CIRT: More New Faces

Identification Of The Interaction Between Rack1-Pcbp1 And Characterization Of The Novel Functional Effect Of The Interaction, Pranjal Nahar-Gohad

Seton Hall University Dissertations and Theses (ETDs)

No abstract provided.

Teachers’ Perceptions On The Changes In The Curriculum And Exit Examinations For Biology And Human Biology, Mirko Krüger, Mihye Won, David F. Treagust

Australian Journal of Teacher Education

In the age of educational accountability, national and state-wide measures are assumed to secure and improve the educational quality. However, educators often wonder how much a new accountability measure may improve the actual teaching and learning practices when the agents of change (teachers) are not active participants of such educational reform. Nevertheless, in Australia, the National Curriculum is rolling in for the first time for K-10 school education in 2012-13. In Western Australia, the new Western Australian Certificate of Education (WACE) system with new compulsory exit examination requirements has been implemented recently for Years 11-12. In this study, using the …

Kinetic And Spectroscopic Studies Of Bicupin Oxalate Oxidase And Putative Active Site Mutants, Ellen W. Moomaw, Eric Hoffer, Patricia Moussatche, John C. Salerno

Faculty Articles

Ceriporiopsis subvermispora oxalate oxidase (CsOxOx) is the first bicupin enzyme identified that catalyzes manganese-dependent oxidation of oxalate. In previous work, we have shown that the dominant contribution to catalysis comes from the monoprotonated form of oxalate binding to a form of the enzyme in which an active site carboxylic acid residue must be unprotonated. CsOxOx shares greatest sequence homology with bicupin microbial oxalate decarboxylases (OxDC) and the 241-244DASN region of the N-terminal Mn binding domain of CsOxOx is analogous to the lid region of OxDC that has been shown to determine reaction specificity. We have prepared a series of CsOxOx …

Development And Characterization Of A Chromotomosynthetic Hyperspectral Imaging System, Randall L. Bostick

Theses and Dissertations

A chromotomosynthetic imaging (CTI) methodology based upon mathematical reconstruction of a set of 2-D spectral projections to collect high-speed (100 Hz) 3-D hyperspectral data cube has been proposed. The CTI system can simultaneously provide usable 3-D spatial and spectral information, provide high-frame rate slitless 1-D spectra, and generate 2-D imagery equivalent to that collected with no prism in the optical system. The wavelength region where prism dispersion is highest (500 nm) is most sensitive to loss of spectral resolution in the presence of systematic error, while wavelengths 600 nm suffer mostly from a shift of the spectral peaks. The quality …

Confocal Imaging Of Transmembrane Voltage By Seer Of Di-8-Anepps, Carlo Manno, Lourdes Figueroa, Robert H. Fitts, Eduardo Rios

Biological Sciences Faculty Research and Publications

Imaging, optical mapping, and optical multisite recording of transmembrane potential (V_m) are essential for studying excitable cells and systems. The naphthylstyryl voltage-sensitive dyes, including di-8-ANEPPS, shift both their fluorescence excitation and emission spectra upon changes in V_m. Accordingly, they have been used for monitoring V_m in nonratioing and both emission and excitation ratioing modes. Their changes in fluorescence are usually much less than 10% per 100 mV. Conventional ratioing increases sensitivity to between 3 and 15% per 100 mV. Low sensitivity limits the value of these dyes, especially when imaged with low light systems …

Death By Birth, Alastair Hunt

Institute for Sustainable Solutions Publications and Presentations

The article offers the author's insights concerning agricultural animal death. The author states that animals die in several reasons including disease, old age, and accidents. The author adds that agricultural animals like beef cattle, dairy cows, and domesticated pigs die in merchandised facilities designed for killing animals to be packed and marketed as food for human beings.

March 2013 Full Issue

NASIG Newsletter

No abstract provided.

Uncoupling Between Dinitrogen Fixation And Primary Productivity In The Eastern Mediterranean Sea, Eyal Rahav, Barak Herut, Noga Stambler, Edo Bar-Zeev, Margaret R. Mulholland

OES Faculty Publications

In the nitrogen (N)-impoverished photic zones of many oceanic regions, prokaryotic organisms fixing atmospheric dinitrogen (N₂; diazotrophs) supply an essential source of new nitrogen and fuel primary production. We measured dinitrogen fixation and primary productivity (PP) during the thermally stratified summer period in different water regimes of the oligotrophic eastern Mediterranean Sea, including the Cyprus Eddy and the Rhodes Gyre. Low N₂ fixation rates were measured (0.8-3.2μmol N m-2 d-1) excluding 10-fold higher rates in the Rhodes Gyre and Cyprus Eddy (~20μmol N m^-2 d^-1). The corresponding PP increased from east to west (200-2500μmol …

Early Life Course Pathways Of Adult Depression And Chronic Pain, Bridget J. Goosby

Department of Sociology: Faculty Publications

Applying cumulative inequality theory, this study examines the extent to which childhood socioeconomic disadvantage and maternal depression increase the risk of major depression and chronic pain in U.S. working-aged adults. Further, I assess whether low socioeconomic status amplifies the risk of adult depression and/or pain. Using data from the 2003 National Comorbidity Survey Replication (N=4339), I find that socioeconomic disadvantage and maternal depression during youth increases the risk of adult depression and/or chronic pain. The probability of having chronic pain increases in magnitude over the life course for adults whose parents have lower educational attainment relative to those with more …

Environmental Literacy Among Students Of The Faculty Of Education At Yarmouk, Ali Al Omari, Salem. A. Al Khawaldeh

Journal of Educational and Psychological Studies

This study aimed at examining the environmental literacy among students of the Faculty of Education at Yarmouk University. The researchers designed a four-part instrument for measuring environmental literacy consisting of: environmental knowledge, attitude towards the environment, environmental practices, and a concern for environmental issues. The sample of the study consisted of 430 male and female students in the second semester of the academic year 2010/2011.The findings revealed that the subjects' level of environmental knowledge and attitudes towards the environment are below the accepted educational standard 75% with a statistically significant difference ( = 0.05), and that the level of environmental …

Assessment Of Early Tumor Response To Cytotoxic Chemotherapy With Dynamic Contrast-Enhanced Ultrasound In Human Breast Cancer Xenografts., Jian-Wei Wang, Wei Zheng, Ji-Bin Liu, Yao Chen, Long-Hui Cao, Rong-Zhen Luo, An-Hua Li, Jian-Hua Zhou

Department of Radiology Faculty Papers

There is a strong need to assess early tumor response to chemotherapy in order to avoid adverse effects from unnecessary chemotherapy and allow early transition to second-line therapy. This study was to quantify tumor perfusion changes with dynamic contrast-enhanced ultrasound (CEUS) in the evaluation of early tumor response to cytotoxic chemotherapy. Sixty nude mice bearing with MCF-7 breast cancer were administrated with either adriamycin or sterile saline. CEUS was performed on days 0, 2, 4 and 6 of the treatment, in which time-signal intensity (SI) curves were obtained from the intratumoral and depth-matched liver parenchyma. Four perfusion parameters including peak …

Research Participants Discuss Stem Conference Participation And Impact On Thinking And Practice, Colleen Beyer, Thomas Koballa, Delena Bell Gatch, Leslie S. Jones, Sharmista Basu-Dutt, Farooq Khan

Physics & Astronomy: Faculty Presentations (1993-2017)

No abstract provided.

President's Newsletter, Brooks Keel

President's Newsletter

No abstract provided.

Suggestive Evidence For Association Between L-Type Voltage-Gated Calcium Channel (Cacna1c) Gene Haplotypes And Bipolar Disorder In Latinos: A Family-Based Association Study, Suzanne Gonzalez, Chun Xu, Mercedes Ramirez, Juan Zavala, Regina Armas, Salvador A. Contreras, Javier Contreras, Albana Dassori, Robin J. Leach, Michael A. Escamilla

Health & Biomedical Sciences Faculty Publications

Objectives: Through recent genome-wide association studies (GWASs), several groups have reported significant association between variants in the calcium channel, voltage-dependent, L-type, alpha 1C subunit (CACNA1C) and bipolar disorder (BP) in European and European-American cohorts. We performed a family-based association study to determine whether CACNA1C is associated with BP in the Latino population.

Methods: This study included 913 individuals from 215 Latino pedigrees recruited from the USA, Mexico, Guatemala, and Costa Rica. The Illumina GoldenGate Genotyping Assay was used to genotype 58 single-nucleotide polymorphisms (SNPs) that spanned a 602.9-kb region encompassing the CACNA1C gene including two SNPs (rs7297582 and rs1006737) previously …

Suggestive Evidence For Association Between L-Type Voltagegated Calcium Channel (Cacna1c) Gene Haplotypes And Bipolar Disorder In Latinos: A Family-Based Association Stud, Suzanne Gonzalez, Chun Xu, Mercedes Ramirez, Juan Zavala, Regina Armas, Salvador A. Contreras, Javier Contreras, Albana Dassori, Robin J. Leach, Michael Escamilla

Health & Biomedical Sciences Faculty Publications

Objectives: Through recent genome-wide association studies (GWASs), several groups have reported significant association between variants in the calcium channel, voltage-dependent, L-type, alpha 1C subunit (CACNA1C) and bipolar disorder (BP) in European and European-American cohorts. We performed a family-based association study to determine whether CACNA1C is associated with BP in the Latino population.

Methods: This study included 913 individuals from 215 Latino pedigrees recruited from the USA, Mexico, Guatemala, and Costa Rica. The Illumina GoldenGate Genotyping Assay was used to genotype 58 single-nucleotide polymorphisms (SNPs) that spanned a 602.9-kb region encompassing the CACNA1C gene including two SNPs (rs7297582 and rs1006737) previously …

Serving God In The Midst Of Multiple Sclerosis: A Holistic And Spiritual Model For Physical Sustainment, Timothy Harville

Doctoral Dissertations and Projects

Multiple Sclerosis is a devastating disease that affects not only the one who suffers with MS, but also their family and relationships leaving the patient feeling depressed and without hope. If the disease is disclosed, many churches and the International Mission Board will reject the person's application because of the potential cost and medical care needed. This author was diagnosed with an aggressive form of Relapsing Multiple Sclerosis in 2008. This writer has experienced the obstacles described above. This model will serve as a motivational tool to help all of us who suffer with MS to use the disability for …

Myths And Fallacies About Male Contraceptive Methods: A Qualitative Study Amongst Married Youth In Slums Of Karachi, Pakistan, Noureen Aleem Nishtar, Neelofar Sami, Anum Faruqi, Shaneela Khowaja, Farid Ul-Hasnain

Community Health Sciences

Pakistan presently has one of the largest cohorts of young people in its history, with around 36 million people between the ages of 15 and 24 years. One of the main reasons for high population growth in Pakistan is almost stagnant contraceptive prevalence rate of 30% nationallyand 17.4% amongst youth. The study was conducted to explore the perceptions regarding myths and fallacies related to male contraceptive methods among married youth aged 18-24 year in Karachi, Pakistan. Qualitative exploratory study design was adopted and a total of eight Focus Group Discussions (FGDs) were conducted. Study was conducted in two Union Councils …

Cell Death Pathways In Directly Irradiated Cells And Cells Exposed To Medium From Irradiated Cells, K.K. Jella, Amaya Garcia, Brendan Mcclean, Hugh Byrne, Fiona Lyng

Articles

Purpose: The aim of this study was to compare levels of apoptosis, necrosis, mitotic cell death and senescence after treatment with both direct radiation and irradiated cell conditioned medium. Materials and methods: Human keratinocytes (HaCaT cell line) were irradiated (0.005, 0.05 and 0.5 Gy) using a cobalt 60 teletherapy unit. For bystander experiments, the medium was harvested from donor HaCaT cells one hour after irradiation and transferred to recipient HaCaT cells. Clonogenic assay, apoptosis, necrosis, mitotic cell death, senescence and cell cycle analysis were measured in both directly irradiated cells and bystander cells Results: A reduction in cell survival was …

Contributors

UNIversitas: Journal of Research, Scholarship, and Creative Activity

No abstract provided.

Additional Routes To Staphylococcus Aureus Daptomycin Resistance As Revealed By Comparative Genome Sequencing, Transcriptional Profiling, And Phenotypic Studies, Yang Song, Aileen Rubio, Radheshyam K. Jayaswal, Jared A. Silverman, Brian J. Wilkinson

Faculty Publications – Biological Sciences

Daptomycin is an extensively used anti-staphylococcal agent due to the rise in methicillin-resistant Staphylococcus aureus, but the mechanism(s) of resistance is poorly understood. Comparative genome sequencing, transcriptomics, ultrastructure, and cell envelope studies were carried out on two relatively higher level (4 and 8 mu g/ml(-1)) laboratory-derived daptomycin-resistant strains (strains CB1541 and CB1540 respectively) compared to their parent strain (CB1118; MW2). Several mutations were found in the strains. Both strains had the same mutations in the two-component system genes waIK and agrA. In strain CB1540 mutations were also detected in the ribose phosphate pyrophosphokinase (prs) and polyribonucleotide nucleotidyltransferase genes (pnpA), a …

Using Seed Mixes In Conjunction With Structured Refuges, M. A. Caprio, J. C. Martinez

Midsouth Entomologist

The U.S. Environmental Protection Agency recently approved, for areas of the Southern U.S., a 5% seed-mixture (Refuge-In-A-Bag or RIB) combined with a 20% external structured refuge for pyramided Bt corn. In this analysis we compared the durability of a pyramided PIP (plant incorporated protectant) deployed with a 20% refuge versus a 5% RIB and an additional 20% external refuge when the larval movement proportion was varied. The results showed that when the PIP expressed a very high dose (overall mortality of susceptibles = 99.99%) and larval movement was 50% and 90%, the 20% external refuge was 38% and 52% more …

Program And Abstracts Of The 59th Annual Conference Of The Mississippi Entomological Association, October 22-23, 2012, Mississippi Entomological Association

Midsouth Entomologist

No abstract provided.

Current Topics In Medical, Urban, And Veterinary Entomology: 4th Annual Roundtable Discussion, K. T. Edwards

Midsouth Entomologist

No abstract provided.