Digital Commons Network^™

Cancer Treatment Using Natriuretic Peptides, David L. Vesely

USF Patents

The present invention includes a method of utilizing four peptide hormones to inhibit the growth of cancer(s). A dramatic decrease in the number of human pancreatic adenocarcinoma cells (i.e., the type of cancer with the highest mortality, with patients only surviving four months) was observed responsive to treatment. The application of the invention would be to utilize one or more of these peptide hormones alone and/or in combination to treat cancer. The ability of these peptide hormones to decrease the number of adenocarcinoma cells has implications for adenocarcinomas at other sites in the body with the majority of cancers of …

Survival In Soviet Gulags: A Secondary Analysis, Kimberly M. Maas, Paul Prew, Elizabeth J. Sandell

Elementary and Literacy Education Department Publications

One of the most common book series on the subject of Soviet Gulags is Evgenia Ginzburg’s “Journey into the Whirlwind” and “Within the Whirlwind.” This paper will use secondary analysis from anthology works with stories similar to Ginzburg's in combination with the works of several other authors like Anne Applebaum (2011) and Geith and Jolluck (2011). It shall also examine extensively Raphaël Lemkin’s definition of genocide and how it fits to what happened in the Gulags. It shall be argued why certain situations that occurred within the Gulags fit this definition. It will also explore the intimate details and lives …

Nitrogen Excretion From Beef Cattle For 6 Cover Crop Mixes As Estimated By A Nutritional Model, E.E. Grings, A. Sackey, M. Hansen, V. Owens, D. Beck, P. Sexton

South Dakota Beef Report, 2013

Excretion of nitrogen (N) from cattle within crop‐livestock systems is an important component of nutrient cycling, but measuring fecal and urinary N excretion in grazing cattle is a difficult and time consuming task. Nutritional models are available to estimate feed utilization and have been used to predict N excretion in grazing cattle. Using the Large Ruminant Nutrition Model, we predicted N losses from mature pregnant beef cows and growing beef heifers from compositional analysis of cover crop mixes grown in central South Dakota. All of the mixes used contained crude protein (CP) concentrations greater than cattle requirements. Estimates of both …

Can Marijuana Be Harmful When Used Prenatally Or During Adolescence?, Penninah Dean

The Science Journal of the Lander College of Arts and Sciences

Marijuana is a popular recreational drug with a strong following campaigning to legalize it for both medicinal and recreational use. This paper serves to illustrate the harmful effects of marijuana use as it pertains to prenatal, adolescent and adult use. By understanding the methods of absorption and mechanism of interaction in the body, we can see a correlation between the effects of marijuana and its toxicity. Through extensive research of case studies on marijuana use we were able to determine marijuana’s harmful effects physically, developmentally and cognitively. Through these methods of research, it can be concluded that marijuana has detrimental …

Full Issue: Volume 6, Number 2

The Science Journal of the Lander College of Arts and Sciences

No abstract provided.

The Carcinogenic Effects Of Aspartame, Devora Sara Gelbfish

The Science Journal of the Lander College of Arts and Sciences

Aspartame, one of the most common artificial sweeteners, is used as a food additive worldwide. Because of early experimentation with rats linking aspartame to higher risk of cancer, there is much concern regarding the safety of aspartame. However, analytical review and numerous subsequent studies have disproven previous experimentation and reaffirmed that aspartame consumption in humans does not increase the risk of cancers. At the current time there is no credible evidence to support the idea that aspartame is carcinogenic. The evidence confirms that at current levels of consumption aspartame is a safe alternative to sucrose.

The Scientific Evidence Validating The Use Of Honey As A Medicinal Agent, Raitzel Chemda Bernstein

The Science Journal of the Lander College of Arts and Sciences

Honey has been used to treat wounds, infections, and other diseases since ancient times. Due to the widespread bacterial resistance to antibiotics, scientists have investigated the healing power of honey. Numerous studies have documented the broad-spectrum antibacterial effect of honey and its success in inhibiting MRSA. The use of honey as a wound dressing has proven to successfully heal chronic wounds in short amounts of time by inhibiting pathogens, reducing inflammation, rebuilding damaged tissue, and minimizing scarring. The mechanisms of action are directly related to the high hydrogen peroxide and rich polyphenol content present in honey. These two components account …

The Pathogenesis And Treatment Of Gout, Daniel Silberstein

The Science Journal of the Lander College of Arts and Sciences

In the past, the etiology of gout was simplistically believed to be based in the generous indulgence of rich foods and alcohol. However, research has revealed that gout has complex environmental and genetic origins. Specifically, researchers have begun to focus attention on the molecular basis of gout and its related features. These features include hyperuricemia, the stages of gout, and the decreased solubility of uric acid. Furthermore, with epidemiologic evidence indicating that the prevalence of gout is consistently rising, it is imperative that medical providers understand the research-based guidelines for treatment. This includes what medications to administer, monitoring for drug-induced …

What Is The Role Of Incretin Mimetics In The Treatment Of Type 2 Diabetes?, Isaac Silberstein

The Science Journal of the Lander College of Arts and Sciences

Type 2 diabetes mellitus (DM) is an intricate disorder defined by insulin resistance, impaired insulin secretion, hyperglycemia, and both microvascular and macrovascular complications. Standard antidiabetic agents like metformin, insulin, sulfonylureas and thiazolidinediones are often insufficient at glucoregulation and do not address the decline in beta cell function that characterizes type 2 diabetes. Moreover, the adverse effects of some of these pharmaceuticals, such as hypoglycemia and weight gain, are disappointing and further limit their clinical utility. Research demonstrates that the actions of two potent incretins. Glucagon-like peptide 1 (GLP-1) and gastric inhibitory polypeptide (GIP), address these concerns as they stimulate beta …

Is There An Alternative Way Of Treating Drug Resistant Epilepsy? The Effects Of The Ketogenic Diet In Children With Intractable Epilepsy, Chaya M. Weinberg

The Science Journal of the Lander College of Arts and Sciences

Many children with epilepsy experience seizures that cannot be resolved with medication. Since surgical intervention is not always an option, the ketogenic diet (KD). a high fat, low carbohydrate and protein diet, offers a chance for seizure reduction and in some cases freedom from seizures and medication. Side effects do exist, although none are serious. Efficacy has been proven through many studies. The mechanism of the KD's effectiveness is still unknown, although several hypotheses exist, including the theory that ketone bodies themselves are anticonvulsant, and the hypothesis that glucose restriction stops seizures. Adenosine A1 receptors are also thought to have …

An Exploration Of Compulsory Licensing As An Effective Policy Tool For Antiretroviral Drugs In India, Dipika Jain, Jonathan J. Darrow

Health Matrix: The Journal of Law-Medicine

No abstract provided.

A Reference Manual For Caregivers Of Individuals With Als, Jessica Pastir, Brianna Woodard

Occupational Therapy Capstones

No abstract provided.

International Health Emergencies In Failed And Failing States, Chiara Giorgetti

Law Faculty Publications

Global health emergencies, particularly those occurring in Jailed and Jailing States, can become threats to the stability of the international community. This Article assesses the international mechanisms available to respond to such emergencies. After defining global health emergencies, it discusses the implications of global outbreaks in Jailed and Jailing States. It then examines the role played by the World Health Organization in controlling global health emergencies, with particular reference to the newly amended 2005 International Health Regulations and the Global Outbreak Alert and Response Network. Finally, it explores the role of other international organizations, including the United Nations Children's Fund …

Enst 594.06: Graduate Seminar: The Politics Of Food, Neva Hassanein

University of Montana Course Syllabi

No abstract provided.

Enst 594.02: The Politics Of Food, Neva Hassanein

University of Montana Course Syllabi

No abstract provided.

Private Standards Organizations And Public Law, Peter L. Strauss

Faculty Scholarship

Simplified, universal access to law is one of the important transformations worked by the digital age. With the replacement of physical by digital copies, citizens ordinarily need travel only to the nearest computer to find and read the texts that bind them. Lagging behind this development, however, has been computer access to standards developed by private standards development organizations, often under the umbrella of the American National Standards Institute (ANSI), and then converted by agency actions incorporating them by reference into legal obligations. To discover what colors the Occupational Safety and Health Administration (OSHA) requires for use in work-place caution …

Accountability And Quality In Higher Education: A Case Study, Trudy Abadie-Mendia

UNF Graduate Theses and Dissertations

The purpose of the present study was to gain a deep and rich understanding of the accountability process at a regional comprehensive university in the Southeast United States. Specifically, the present study sought to answer the following question: How is a regional comprehensive university in the Southeast United States substantiating the quality of undergraduate professional programs and the success of graduates. The study utilized a qualitative research methodology, specifically a descriptive embedded case study design. A total of 16 interviews were conducted with participants representing the program level, college level, and administrative level. Three subunits of investigation provided the program …

Plant-Pathogen Interactions Associated With Wasting Disease In The Tropical Seagrass Thalassia Testudinum., Kyle Loucks

UNF Graduate Theses and Dissertations

Lipopolysaccharide (LPS) was shown to serve as a strong elicitor of the early defense response in the subtropical seagrass Thalassia testudinum Banks ex König and was capable of inducing an oxidative burst identified at the single cell level. The formation of reactive oxygen species (ROS) included a diphenylene iodonium sensitive response, suggesting the involvement of an NADPH oxidase. A 900 bp fragment of this enzyme was sequenced and found to encode a NAD binding pocket domain with extensive homology to the Arabidopsis thaliana rbohF (respiratory burst oxidase homolog) gene. Pharmacological dissection of the early events preceding ROS emission revealed that …

Bacteriostatic Effects Of Sucralose On Environmental Bacteria, Arthur Phillip Omran Jr.

UNF Graduate Theses and Dissertations

Sucralose is a zero calorie sweetener developed and manufactured by Tate and Lyle Sweetener Company in the 1980’s. They sell the sweetener compounded with maltodextrin and dextrose under the brand name Splenda®. Sucralose was developed as a low cost artificial sweetener that is non-metabolizable in humans and can withstand changes in pH and temperature. It is not degraded by the waste water treatment process. Since the molecule can withstand heat, acidification and microbial degradation it is accumulating in the environment, and has been found in waste water, estuaries, rivers and the Gulf Stream. The highest concentration of environmental sucralose detected …

Comparative Sugar Transport By Crustacean Hepatopancreas And Intestine, Ada Duka

UNF Graduate Theses and Dissertations

Glucose is transported in crustacean hepatopancreas and intestine by Na⁺-dependent co-transport, while Na⁺-dependent D-fructose influx has only been described for the hepatopancreas. It is still unclear if the two sugars are independently transported by two distinct cotransporter carrier systems. In this study lobster (Homarus americanus) hepatopancreas brush border membrane vesicles (BBMV) were used to characterize, in detail, the cation-dependency of both D-[³H] glucose and D-[³H] fructose influxes, while in vitro perfused intestines were employed to determine the nature of cation-dependent sugar transport in this organ. Over the sodium concentration range …

The Effects Of Multiple Abiotic Stressors On The Susceptibility Of The Seagrass Thalassia Testudinum To Labyrinthula Sp., The Causative Agent Of Wasting Disease, Nichole Danielle Bishop

UNF Graduate Theses and Dissertations

In the past century, seagrasses have experienced massive die off episodes in what has been collectively referred to as “wasting disease.” Researchers generally agree that wasting disease is caused by a protist of the Labyrinthula genus, and that environmental stressors can make some populations of seagrasses more susceptible to infection. The purpose of this study was to examine the combined effects of elevated salinity, elevated temperature, elevated sulfide and night-time hypoxia on Thalassia testudinum health and its response to Labyrinthula sp. infection under controlled conditions. To test these effects, microcosms were utilized and individual seagrass shoots were randomly assigned to …

A Survey Of The Taxonomy Of The Cyanobacteria From Northeast Florida, Descriptions Of Novel Taxa, And An Investigation Into The Factors Which Influence The Epibenthic Cyanobacterial Community, Holly Stephanie Stocks

UNF Graduate Theses and Dissertations

Cyanobacteria are important components of the aquatic system, valued for their oxygen production, nitrogen fixation, and as the base of many aquatic food webs. This study investigated several aspects of cyanobacteria such as the diversity and response to nutrient enrichments. A survey of Northeast Florida was conducted between the years of 2010 and 2012; a total of 145 taxa were identified in freshwater habitats, such as springs, lakes, rivers, and retention ponds. While surveying the St. Johns River in Jacksonville, Florida, a novel Stigonematalean taxon was isolated and cultured. Subsequent morphological and genetic analyses indicate that this taxon is related …

Nutrient Availability Affects Flowering Rate But Has Limited Influence On Morphology Of The Hooded Pitcher Plant, Sarracenia Minor., Justin M. Lemmons

UNF Graduate Theses and Dissertations

Carnivorous plants perform as both producers and consumers. Botanical carnivory has evolved in sunny, moist, nutrient-poor environments, and the primary nutrient supplied by prey is proposed to be nitrogen. There is a trade-off between carnivorous and photosynthetic structures which corresponds to degree of carnivory expression and available nutrients. This study was conducted on the hooded pitcher plant, Sarracenia minor, which is a facultative wetland plant and Florida-threatened species. Sarracenia minor is considered a specialist myrmecophage and ants characterize the majority of attracted and captured prey. Ants not only provide nutritional benefit, but also protection against herbivory. A natural population …

The Republic Of Choosing: A Behaviorist Goes To Washington, William H. Simon

Faculty Scholarship

Cass Sunstein’s book Simpler recounts the author’s efforts during his tenure in the first Obama administration to apply the policy tools he helped derive from behavioral economics. In this review, I suggest that, while Sunstein reports some notable achievements, he exaggerates the utility of the behaviorist toolkit. Behaviorist-inspired interventions are marginal to most of the largest policy problems, and they played little role in the Obama administration’s most important initiatives. The book also reflects a misguided political strategy.

Becker And Foucault On Crime And Punishment – A Conversation With Gary Becker, François Ewald, And Bernard Harcourt: The Second Session, Gary S. Becker, Francois Ewald, Bernard E. Harcourt

Faculty Scholarship

In his 1979 lectures at the Collège de France, The Birth of Biopolitics, Michel Foucault discussed and analyzed Gary Becker’s economic theory of crime and punishment, originally published in The Journal of Political Economy in 1968 under the title “Crime and Punishment: An Economic Approach.” In this historic, second encounter at the University of Chicago, Gary Becker responds to Foucault’s lectures and possible critical readings of his writings on crime and punishment, in conversation with Professors François Ewald (who was, at the time in 1979, Foucault’s assistant at the Collège and one of Foucault’s closest interlocutors) and Bernard Harcourt (a …

Machine Speech, Tim Wu

Faculty Scholarship

Computers are making an increasing number of important decisions in our lives. They fly airplanes, navigate traffic, and even recommend books. In the process, computers reason through automated algorithms and constantly send and receive information, sometimes in ways that mimic human expression. When can such communications, called here “algorithmic outputs,” claim First Amendment protection?

The Returns To Criminal Capital, Thomas Loughran, Holly Nguyen, Alex R. Piquero, Jeffrey Fagan

Faculty Scholarship

Human capital theory (Becker 1962; Mincer 1958; Schultz 1960; 1961) posits that individuals can increase their labor market returns through investments in education and training. This concept has been studied extensively across several disciplines. An analog concept of criminal capital, while the focus of speculation and limited empirical study, remains considerably less developed theoretically and methodologically. This paper offers a formal theoretical model of criminal capital indicators and tests for greater illegal wage returns using a sample of serious adolescent offenders, many of whom participate in illegal income-generating activities. Our results reveal that, consistent with human capital theory, there are …

International Law In A Time Of Scarcity: An Introduction, Harlan G. Cohen

Scholarly Works

Does international law have the resources to manage, if not solve, this complex global problem of scarcity? Different areas of international law governed by different regimes have their own ways of conceptualizing and managing scarcity. International human rights law may frame the problem as one of individual economic and social rights or as one of the right of indigenous groups. For the most part though, these models from different areas of international law operate in isolation from one another, following their own internal logics.

The problem of scarcity has started to get the attention of international law scholars and experts, …

Health Check: Analyzing Trends In West Michigan 2013, Grand Valley State University

Health Check: Analyzing Trends in West Michigan

No abstract provided.

Are Women Aware? : Factors Related To Women's Knowledge Of Risk And Preventive Factors In Breast Cancer, Sandra M. Walther

Dissertations

Problem. Women have a one-in-eight chance of being diagnosed with breast cancer in their lifetime. In the past decade, there has only been a decrease of less than 1% in breast cancer morbidity and mortality rates. Breast cancer continues to be a feared disease that ravages even its survivors, and grips many with fear. Furthermore, breast cancer remains the highest cost of care among cancers. In 1990 the overall cost of care for breast cancer was $4.2 billion. In 2010, the total cost of breast cancer care rose to almost $17 billion, and by 2020 the cost trends show …