Digital Commons Network^™

Community Resources For Older Adults With Age-Related Disabilities And Chronic Conditions: A Scoping Review, Oejin Shin, Sojung Park, Soobin Park, Sarah Sunghye Kang, Sunghei Han, Eunsun Kwon, Seoyeon Ahn, Borin Kim

Faculty Publications - Social Work

Community resources are essential for supporting older adults with disabilities and chronic conditions, yet how these resources are conceptualized and evaluated across the empirical literature remains unclear. This scoping review synthesizes U.S.-based research on community resources for older adults with age-related disabilities and chronic conditions, guided by the PAGER framework. Following PRISMA-ScR guidelines, we searched MEDLINE, PsycINFO, CINAHL, and Web of Science, ultimately including 21 peer-reviewed studies. Findings reveal four primary resource domains: healthcare-based services, home- and community-based services (HCBS), behavioral health supports, and environmental or structural resources. Accessibility and utilization emerged as the most consistently examined dimensions, while quality …

The Crisis Of Appropriations Law, Samuel R. Bagenstos

Articles

Appropriations law is a unique body of federal law.  Appropriations law imposes its own somewhat baroque set of statutory interpretation principles, approves of very broad delegations to the Executive Branch without meaningful limiting principles, and is often exempt from judicial review.  But perhaps that is all about to change.  Donald Trump’s historically aggressive challenge to Congress’s power of the purse has spurred an unusually large volume of exceptionally high-stakes appropriations law litigation. 

The potential implications go beyond the high-profile issues such as enforcement of the Impoundment Control Act.  In general, the unusual features of appropriations law are built on a …

Senolytic-Resistant Senescent Cells Have A Distinct Sasp Profile And Functional Impact: The Path To Developing Senosensitizers, Utkarsh Tripathi, Masayoshi Suda, Vagisha Kulshreshtha, Bryan T Piatkowski, Allyson K Palmer, Nino Giorgadze, Christina Inman, Nathan Gasek, Ming Xu, Kurt O Johnson, Tamar Pirtskhalava, Selim Chaib, Larissa P G Langhi Prata, Yi Zhu, Renuka Kandhaya-Pillai, Stefan G Tullius, Saranya P Wyles, Rambabu Majji, Hari Krishna Yalamanchili, David B Allison, Tamar Tchkonia, James L Kirkland

Faculty, Staff and Students Publications

The senescent cell (SC) fate is linked to aging, multiple disorders and diseases, and physical dysfunction. Senolytics, agents that selectively eliminate 30%-70% of SCs, act by transiently disabling the senescent cell antiapoptotic pathways (SCAPs), which defend those SCs that are proapoptotic and pro-inflammatory from their own senescence-associated secretory phenotype (SASP). Consistent with this, a JAK/STAT inhibitor, Ruxolitinib, which attenuates the pro-inflammatory SASP of senescent human preadipocytes, caused them to become "senolytic-resistant". Administering senolytics to obese mice selectively decreased the abundance of the subset of SCs that is pro-inflammatory. In cell cultures, the 30%-70% of human senescent preadipocytes or human umbilical …

In Vivo Volumetric Visualization And Quantification Of Cumulus Expansion In Mice With Intravital Optical Coherence Tomography, Kohei Umezu, Frank J Brooks, Irina Larina

Faculty, Staff and Students Publications

Ovulation is preceded by a critical physiological process known as cumulus expansion, during which the cumulus cell layer surrounding the oocyte undergoes structural remodeling. Despite the recognized importance of this process for reproductive success, live quantitative imaging of cumulus expansion has not been previously achieved due to limitations of current imaging technologies for deeply located ovaries. In this study, we employed intravital optical coherence tomography for three-dimensional visualization of mouse follicles containing cumulus-oocyte complexes (COC) within the physiological context of the ovary, both ex vivo and in vivo. This method enabled time-lapse measurement of cumulus layer thickness and COC …

Findings And Recommendations From The State Of The Art (Sota) Conference On Nursing Research To Improve Veteran Outcomes, Amelia E Schlak, Sarah Krein, Laura A Petersen, David Atkins, Catherine Battaglia, Elizabeth Burkhart, Renee Colsch, Marguerite Daus, Heather Gilmartin, Nipa Kamdar, Melissa Knox, Ann Kutney-Lee, Christine M Olney, Kathryn Rugen, Tracy Weistreich, Sheila Cox Sullivan, On Behalf The Nursing Sota Planning Committee

Faculty, Staff and Students Publications

The Veterans Health Administration (VHA), the largest employer of nurses in the United States, has more than 120,000 nursing personnel providing care to over 9 million Veterans across diverse settings. Despite nursing's central role in delivering and sustaining care, research on strengthening the nursing workforce and optimizing nursing practice has remained underdeveloped in VHA. To address this gap, VHA's Office of Research and Development, in partnership with the Office of Nursing Services, convened a State of the Art (SOTA) conference in November 2023 focused on nursing. The Nursing SOTA brought together nurses, researchers, operational leaders, and other stakeholders to review …

A Year In Review On Tuberculosis And Non-Tuberculous Mycobacteria Disease: A 2026 Update For Clinicians And Scientists, Simone Tunesi, Graham Bothamley, Gunar Günther, Yousra Kherabi, Liga Kuksa, Berit Lange, Christoph Lange, Natalie Lorent, Francesca Saluzzo, Martina Sester, Xenia Emilie Sinding Iversen, Marc Tebruegge, Conor Tweed, Anca Vasiliu, Lorenzo Guglielmetti, Tuberculosis Network European Trials Group (Tbnet)

Faculty, Staff and Students Publications

Background: Tuberculosis (TB) remains a major cause of morbidity and mortality worldwide, while infections from non-tuberculous mycobacteria (NTM) represent a growing public health threat. In its 20th year of activity, the Tuberculosis Network European Trials group (TBnet; www.tbnet.eu) is one of the leading research networks in Europe. In this review, we summarize the main advances in TB and NTM that occurred in 2025.

Methods: We conducted a non-systematic review of articles published in 2025, with a strong emphasis on research with current or potential impact on clinical practice. We also selected the most impactful papers regarding the management of adult …

Comparing Rotational Thromboelastometry And Standard Coagulation Assays For Predicting Intraoperative Bleeding In Pediatric Liver Transplantation, Kirby Deshotels, Trung Nguyen, Jun Teruya, Muhammed Umair M Mian, Kelby Fuller, Sanjiv Harpavat, Anna Banc-Husu, Amir Navaei, John Goss, Moreshwar Desai, Arun Saini

Faculty, Staff and Students Publications

Background: Utility of preoperative rotational thromboelastometry (ROTEM) over standard coagulation assays (SCAs) in predicting intraoperative bleeding during orthotopic liver transplantation (OLT) in children with liver failure (LF) remains unclear.

Methods: In this single-center retrospective cohort of pediatric OLT recipients, we compared the predictive values of preoperative ROTEM parameters (intrinsic pathway (INTEM) maximum clot firmness (MCF), extrinsic pathway (EXTEM) clotting time (CT), INTEM CT, and fibrinogen-based (FIBTEM) MCF) and the corresponding SCAs (platelet count, international normalized ratio (INR), activated partial thromboplastin time (aPTT), and fibrinogen level, respectively) for significant intraoperative bleeding (blood loss of > 22 mL/kg; i.e., ≥ 85th percentile for …

Exploring The Association Between Internal Body Temperature And Metabolic Status In Early Lactation Jersey Cattle, Alexandra Ferreri, Claira Seely

Honors Theses and Capstones

No abstract provided.

Factors Affecting Percentage Of Low Birth Weight In Ohio, Maureen Schmid, Mira Krishnan

Scholarship in Medicine - All Papers

A multitude of environmental factors correlate to negative outcomes on maternal and fetal health such as low birth weight. While studies reveal that housing quality, air pollution, and stress contribute to negative birth outcomes, it is unclear which housing factors have the greatest impact and how rural, suburban, and urban settings in the U.S. differ. The objective of this study was to delve into how environmental factors such as housing quality and community type impact low birth weight in Ohio. This study used publicly available data from County Health Rankings and Roadmaps to examine how different housing conditions correlate to …

Exploring Demographic Factors Relating To Low Birth Weight In Rural Vs Urban Ohio, Meghan Curran, Jessica Terrell

Scholarship in Medicine - All Papers

Although medical advancements have improved the outcomes for infants born with low birth weight (LBW), these interventions are very expensive and low birth weight still was attributed to 16.1% of infant deaths in the United States in 20201. By understanding the factors that influence the incidence of low birth weight in the United States, preventative measures can be implemented to reduce the need for costly interventions and enhance infant health outcomes. In this study, we focused on 38 counties in Ohio that had either 75% or greater rural regions or 30% or less rural regions. Additionally, we focused on four …

Competencies, Knowledge, And Skills Of Effective School Nutrition Program Directors, Kymberle Gordon Phd, Jane Peterson Phd Rdn

Institute of Child Nutrition, Applied Research Division

Abstract
School nutrition program directors play a vital leadership role in ensuring school meal programs operate efficiently, effectively, and in compliance with federal, state, and local requirements. Competencies, knowledge, and skills (CKS) frameworks support these professionals by defining performance expectations, guiding professional development, and strengthening leadership capacity. The most recent CKS resource for school nutrition program directors was published in 2010, and substantial changes in regulatory requirements, operational complexity, workforce conditions, and leadership expectations have created a need for revision.

This study aimed to identify and validate the competencies, knowledge, and skills required for effective school nutrition program directors in …

Communicating With The Virtual Patient: Student Perceptions Of Genai In Dietetic Training, Suzanne Doyle Dr, Aileen Kennedy Dr

Case studies: Digital Education

Background: Communication skill development is a key component of dietetic education. Traditional teaching methods such as role play and simulated consultations are effective but resource intensive. Generative artificial intelligence (GenAI) may provide an accessible supplementary tool for communication skills practice. This initiative aimed to explore dietetic students’ experiences of using a GenAI simulated patient consultation as a revision aid to support communication skill development.

Methods: This evaluation involved second-year BSc Human Nutrition and Dietetics students undertaking the Professional Practice and Communications module. Following six face-to-face communication workshops, students completed a GenAI simulated consultation involving a 56-year-old male recently diagnosed with …

What Is The Evolving Role Of Nurses In Telehealth As Future Healthcare Professionals?, Emma G. Lowry

Honors College Theses

Telehealth has evolved into an essential component of healthcare delivery in today's world, something that occurred alongside the COVID-19 pandemic. As healthcare professionals, nurses must be adequately prepared and equipped to use the tools for telehealth. This paper examines the evolving role of nurses in telehealth by assessing undergraduate nursing students’ and practicing nurses’ knowledge, attitudes, and perceived competencies. Data will be collected through a Qualtrics survey utilizing the Awareness, Knowledge, Attitude, and Skills (AKAS) Scale for Telemedicine, supplemented by interviews with telehealth practitioners to provide qualitative context. It is expected that variations in proficiency and attitudes, from previous biased …

Crisis Communication In The Influencer Era: A Crisis Response Analysis Of Poppi And Alani Nu, Meredith E. Staley

Honors College Theses

As social media continues to reshape modern public relations practice, beverage brands like Alani Nu and Poppi offer relevant examples of influencer-driven communication and crisis response. This honors thesis compares and contrasts these brands following two major crises: Poppi’s influencer vending machine campaign and the health concerns and backlash surrounding Alani Nu’s energy drinks. Despite the well-known prevalence of these brands, there is little scholarly research examining their crisis communication strategies. Guided by Situational Crisis Communication Theory, this study uses a combination of social and news media content analysis to evaluate how each brand responded to its respective crisis. Each …

The Role Of Ot In Enhancing Mental Health Outcomes For Primary Care Patients, Amorelle Upton

Occupational Therapy Capstones

Purpose. Primary care settings often serve as the first point of contact for individuals experiencing mental health concerns. However, occupation-based and function-focused interventions remain underutilized in these settings. The purpose of this Doctoral Experiential Capstone (DEC) was to implement an Occupational Therapy Mental Health Toolkit designed to support holistic and integrative mental health care in primary care settings.

Methods. This project was guided by the ecology of human performance (EHP) model. Methods included a literature synthesis, development of a Memorandum of Understanding (MOU) and structured learning objectives, contextual needs assessment through stakeholder collaboration and site observation, and a product design, …

Supporting Reentry: An Occupation-Based Approach, Savannah B. Ullyott

Occupational Therapy Capstones

Introduction: Individuals transitioning back into the community following incarceration need holistic care to support a successful reintegration process (National Institute of Justice [NIJ], 2023). There are a variety of supports and barriers to successful reintegration that should be considered when guiding programming for this population, as these individuals often face many challenges when transitioning back into the community (Galletta et al., 2021). Specific supports facilitating successful transitions back into the community includes those of basic or daily needs, often related to housing, employment, transportation, social supports, food security, and access to mental and physical health services (Galletta et al., 2021; …

Early Occupational Therapy Services: Addressing Health Disparities Following Discharge From The Nicu, Ellie Maree Schumacher

Occupational Therapy Capstones

Background and Purpose: One out of ten infants born in the United States are admitted to the Neonatal Intensive Care Unit (NICU); a status that has been directly linked to ongoing infant health disparities and disabilities, requiring continued support and education following discharge (Griffith et al., 2022; National Center for Health Statistics, 2025). NICU graduates and their families work with occupational therapy to address or prevent developmental delays and ensure well-being (Craig, 2018; Riley & de Sam Lazaro 2021).

Methodology: A literature review was conducted to determine the needs of the population and context and include NICU admissions, family needs, …

Caregiver Resources For Children With Sensory Needs, Kennedy E. Reimann

Occupational Therapy Capstones

Purpose: Children with autism spectrum disorder (ASD) frequently experience sensory processing differences that impact participation in daily activities, social engagement, and family routines. These challenges often extend beyond the child, influencing caregiver well-being and overall family functioning. Although occupational therapy (OT) plays a critical role in addressing sensory processing needs through sensory-based interventions and environmental modifications, caregivers often report limited access to clear, practical, and evidence-based resources. The purpose of this scholarly project was to develop caregiver-friendly educational materials that translate sensory-based strategies into accessible and practical tools for everyday use.

Methods: This project was guided by the Ecology of …

Achieving Successful Occupational Performance During Transitions In Eating Disorder Treatment, Elise Kay Ramberg

Occupational Therapy Capstones

Introduction: Individuals with eating disorders experience challenges in occupational engagement that stem from contributing meaning, value, and purpose to occupations that support eating disorder behaviors rather than promote quality of life (Mack et al., 2023). Recovery is highly dependent on the transition between both levels of care and back into the patient’s natural environment. Occupational therapists play an essential role in supporting patients as they transition and learn to re-engage in their lives outside of their eating disorder (Mack et al., 2023). The purpose of this project was to create materials for the occupational therapist to employ with eating disorder …

The Therapy Behind The Tractor: An Occupational Therapists’ Guide For Treating Farmers, Allison Haiby

Occupational Therapy Capstones

Background: Historically, farming is known as a highly laborious job, placing farmers at increased risk for injury. Despite an injury, the farm must continue to be cared for. Although occupational therapy cultivates client-centered care, many therapists have limited knowledge of farming culture and best practice methods to integrate the demands of farming into therapy.

Purpose: The purpose of this scholarly project was to develop an educational guide, Built for the Farm: An Occupation-Based Guide for Therapists Working with Farmers, to support therapists treating farmers. The guide promotes culturally informed, occupation-based strategies to strengthen therapeutic relationships and improve the healthcare experiences …

Mitigating The Effects Of Technology Use In The Classroom: An Occupational Therapy Approach, Hannah E. Ibach

Occupational Therapy Capstones

Background: The average child spends three times the recommended time on technology, which is leading to a wide range of consequences affecting education, such as fine motor, cognitive, and social deficits (Christensen, 2021; McGough, 2021; Qi et al., 2023). Parents and teachers play a crucial role in helping children be prepared for their education, yet many are not aware of the impacts of too much technology use (Srivastava, 2022). Developing strong foundational skills early in childhood is critical for setting the stage for long-term educational success. When skills are nurtured from a young age, children are better prepared to adapt …

Development Of Feed In Context: A Context-Responsive Pediatric Feeding Guide For Rural Practice Guided By The Ecology Of Human Performance Model, Jatin Lee Cranmore

Occupational Therapy Capstones

Background: Pediatric feeding participation is influenced by complex interactions among sensory processing, motor coordination, emotional regulation, caregiver routines, and environmental conditions. When feeding challenges occur, the impact extends beyond nutrition and may limit participation in family routines, school environments, and community activities (St. John et al., 2026; St. John & Ausderau, 2024). Access to specialized feeding services can be particularly limited in rural communities where healthcare workforce shortages and geographic barriers reduce the availability of pediatric rehabilitation services (Tak et al., 2022). Occupational therapy practitioners are uniquely positioned to address feeding participation because occupational therapy practice examines the interaction among …

Long‑Term Impacts Of A Composted Sewage Sludge–Based Class B Organic Fertilizer On Soil Micronutrients And Crop Production In The Tropics, Luana Corrêa Silva, Aline Renée Coscione, Rodrigo Silva Alves, Philippe Solano Toledo Silva, Adrielle Rodrigues Prates, Leiliane Dutra Silva, Fabrício Da Silva Vasconcelos, Jussara Borges Regitano, Cassio Hamilton Abreu-Junior, Wanderley José De Melo, Gian Franco Capra, Arun Dilipkumar Jani, Thiago Assis Rodrigues Nogueira

Biology, Agriculture and Chemistry Faculty Publications and Presentations

Organic fertilizers, such as Class B materials (e.g., composted sewage sludge, CSS), may contain high levels of plant micronutrients, but their use in crop production needs to be monitored to avoid environmental problems. In this study, we sought to understand the Cu, Mn, and Zn dynamics in tropical soils and their residual effects on maize and wheat productivity, after three CSS applications. A randomized complete block experimental design with six treatments and four replicates was implemented. CSS rates (0.0, 5.0, 7.5, 10.0, and 12.5 Mg ha⁻¹) were compared with conventional mineral fertilizer (CMF). Over a six-year period encompassing …

Aquatic Macrophytes As Nature-Based Solutions: Challenges And Opportunities Across Inland And Coastal Waters, Morgan Botrel, Roxane Maranger, Lindsay L. Trottier, Mathieu Cusson, Lars L. Iverson, Fanny Noisette, Christian Nozais, Katrine Turgeon, Andrea Bertolo, Thibaud André-Alphonse, Simon Bélanger, Arthur De Grandpré, Jean-Olivier Goyette, Sabine Hilt, Ladd Johnson, Valérie Langlois, Martin Laporte, Félix Lauzon, Brigitte Légaré, Anne Ola, Marie-Pomme Presne-Poissant, Matthieu Prugne, Caroline Susini, Richard Zimmerman

OES Faculty Publications

Macrophytes are foundation species whose use as nature-based solution (NbS) in aquatic ecosystems can help reduce climate change impacts while mitigating biodiversity loss. The discrepancy in research and application of macrophytes as NbS across inland and marine coastal ecosystems is an opportunity to expand the concept and learn from different approaches. We report on an initiative uniting marine and freshwater scientists that compared knowledge on macrophytes as NbS across realms, identified advances and gaps in their use, and synthesized challenges and opportunities for application. We conducted a bibliometric analysis and an expert participatory exercise around recent review papers. We reveal …

Herbivore Identity And Species Richness Shape Fruit Chemical And Quality Responses To Foliar Herbivory, Xavier Ozowara, Taylor M. Sloey, Susan R. Whitehead

Biological Sciences Faculty Publications

The cascading consequences of foliar herbivory on fruit chemistry and quality remain relatively underexplored, with most existing studies focusing on the effects of only one or two attackers. In this study, we examine how increasing herbivore species richness during foliar herbivory alters strawberry (Fragaria × ananassa Duch) fruit quality and phenolic chemistry. We conducted a greenhouse experiment with single species feeding and different combinations of feeding by three generalist lepidopteran species: Spodoptera frugiperda, Heliothis virescens, Helicoverpa zea. Species fed on leaves for 72 h as fruits ripened, and fully ripe fruits were harvested 72 h after …

Molar-Incisor Hypomineralization: Diagnosis, Management, And Treatment, Giovana Anovazzi Medeiros Dds, Msc, Phd, Bahareh Enghiad Dmd, James R. Boynton Dds, Ms

The Journal of the Michigan Dental Association

Molar Incisor Hypomineralization (MIH) is a qualitative developmental enamel defect affecting at least one permanent first molar. Characterized by high porosity and reduced mineral content, MIH leads to hypersensitivity, post-eruptive breakdown, and increased caries susceptibility. The etiology is multifactorial, typically occurring between birth and four years of age. Management depends on severity, ranging from topical fluorides and sealants for mild cases to stainless-steel crowns or extractions for severe instances. Because porous enamel facilitates bacterial penetration and pulpal inflammation, achieving effective local anesthesia is often difficult, necessitating individualized behavioral management and early intervention to preserve tooth structure.

Mir-302 Regulates Pancreatic Progenitor Pool And Pancreatic Size, Ziyue Z Yang, Caroline G Snider, Ronald J Parchem

Faculty, Staff and Students Publications

Disruptions in pancreatic development can lead to health issues such as pancreatic agenesis and congenital diabetes mellitus. Understanding pancreatic organogenesis is critical for elucidating disease mechanisms and developing regenerative therapies. The pancreas consists of endocrine and exocrine cells, both of which are derived from multipotent progenitor cells (MPCs). MPC proliferation and differentiation are tightly controlled by multiple mechanisms, including post-transcriptional regulation by miRNAs. However, these regulatory factors are not fully understood. Here, we profiled miRNA expression in MPCs and identified that mir-302 was highly enriched during the earliest stages of pancreatic development. Loss of mir-302 resulted in reduced pancreatic size …

Empowering Through Structured Boundaries: An Integral Model For Fostering Balanced Eating And Nutritional Well-Being, Citrine Elatrash, Colleen Macke, Jenna Shi, Theresa Wilson, Sarah H Elsea, Stephanie Sisley

Faculty, Staff and Students Publications

Purpose: Treating obesity in complex disorders requires individualized health management plans. Effective obesity management in the Smith-Magenis syndrome (SMS) population has multiple inherent barriers related to their cognitive impairments, anxiety, behavioral disturbances, and sleep disorders. However, to date, no research exists related to strategies caregivers successfully employ to help individuals with SMS manage their food intake and mitigate associated behaviors.

Methods: We performed a qualitative thematic analysis of group interviews from 23 caregivers representing 21 individuals with SMS. Hybrid thematic analysis revealed that successful strategies employed by caregivers in this unique population revolved around a global theme of Empowering Through …

Amino Acids And Lean Mass Accretion In Preterm Neonates, Antonio C Ramos Dos Santos, Marta L Fiorotto, Teresa A Davis

Faculty, Staff and Students Publications

Purpose of review: This review evaluates recent evidence on how total protein and energy intake, amino acid composition, and nutrient delivery modality influence protein synthesis in preterm neonates, with the goal of informing nutritional strategies to support optimal lean mass accretion and growth.

Recent findings: Preterm neonates exhibit anabolic resistance to feeding due to impaired insulin and amino acid signaling in skeletal muscle. Enteral nutrition, especially fortified human milk, supports better lean mass accretion and neurodevelopment than parenteral nutrition. Intermittent bolus feeding and pulsatile leucine supplementation during continuous feeding further enhance mTORC1-dependent translation initiation signaling and protein synthesis efficiency in …

Evolving Burden Of Metabolic Dysfunction-Associated Steatotic Liver Disease And Its Complications In A Us Nationwide Healthcare System, Basim Ali, Ronald Samuel, Jennifer R Kramer, Liang Li, Xian Yu, Yumei Cao, Roxanne Desiderio, George Cholankeril, Steven M Asch, Hashem B El-Serag, Fasiha Kanwal

Faculty, Staff and Students Publications

Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a growing public health problem. Measuring the burden of cirrhosis and its complications in people with MASLD is important to inform health care delivery.

Methods: We aimed to quantify the changes in the burden of MASLD-related cirrhosis and hepatocellular carcinoma (HCC) in a nationwide U.S. healthcare system. We used data from the Veterans Health Administration to examine temporal trends between 2010 and 2021 in the annual incidence and prevalence of cirrhosis and HCC in a large cohort of patients with MASLD, and to compare them to those in patients with hepatitis C …