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Advances In Fluid And Thermal Transport Property Analysis And Design Of Sintered Porous Wick Microstructures, K. K. Bodla, J. A. Weibel, S V. Garimella

CTRC Research Publications

Sintered porous structures are ubiquitous as heat transport media for thermal management and other applications. In particular, low-porosity sintered packed beds are used as capillary-wicking and evaporation-enhancement structures in heat pipes. Accurate prediction and analysis of their transport characteristics for different microstructure geometries is important for improved design. Owing to the random nature and geometric complexity of these materials, development of predictive methods has been the subject of extensive prior research. The present work summarizes and builds upon past studies and recent advances in pore-scale modeling of fluid and thermal transport within such heterogeneous media. A brief review of various …

Robust Polyhedral Minkowski Sums With Gpu Implementation, Min-Ho Kyung, Elisha P. Sacks, Victor Milenkovic

Department of Computer Science Technical Reports

No abstract provided.

Roles Of Jnrap2.6-Like From The Transition Zone Of Black Walnut In Hormone Signaling, Zhonglian Huang, Peng Zhao, Jose Medina, Richard Meilan, Keith E. Woeste

Department of Forestry & Natural Resources Faculty Publications

An EST sequence, designated JnRAP2-like, was isolated from tissue at the heartwood/sapwood transition zone (TZ) in black walnut (Juglans nigra L). The deduced amino acid sequence of JnRAP2-like protein consists of a single AP2-containing domain with significant similarity to conserved AP2/ERF DNA-binding domains in other species. Based on multiple sequence alignment, JnRAP2-like appears to be an ortholog of RAP2.6L (At5g13330), which encodes an ethylene response element binding protein in Arabidopsis thaliana. Real-time PCR revealed that the JnRAP2-like was expressed most abundantly in TZ of trees harvested in fall when compared with other xylem tissues harvested in the …

Business Language Studies And Study Abroad In “A Changed World”, Deb S. Reisinger

Global Business Languages

Postsecondary institutions increasingly focus their efforts on internationalization, but foreign language faculty and language and literature departments are conspicuously absent from the great majority of these discussions (Knight 2006, Gerndt 2012). The emerging field of Business Language Studies (Doyle 2012) offers an important path to participating in these decisions and thus to helping shape the discussions about developing our students’ global and intercultural competencies. The purpose of this article is twofold. On the one hand, we will show how BLS aligns with recent pedagogical trends put forth by national associations (MLA, ACTFL, AAUC), underscoring the importance of showcasing its work …

Experimental Pedagogy In A Course On International Business In French, Marie-Pascale Pieretti

Global Business Languages

This article showcases “International Business in French,” a course developed at Drew University, with a special focus on ways in which students use their experience to construct knowledge of the world of business and economics in a variety of Francophone contexts. To illustrate the value experiential pedagogy can add to a business language course, it examines in particular the ways in which a trip to Quebec, the study abroad component embedded in the course, reinforces, challenges, and reveals ambiguities concerning the knowledge acquired in class prior to the trip. In conclusion, it outlines and discusses the challenges such a pedagogy …

The Sudden Selector's Guide To Physics Resources, Michael Fosmire

Libraries Faculty and Staff Scholarship and Research

This book provides a foundation to the resources and services unique to physics librarianship that will help you work successfully with your users. The first part of the book includes an overview of the discipline, including current hot topics of research (chapter 1), a brief introduction to the library liaison role (chapter 2), an analysis of the life cycle of information in physics and how physicists use different kinds of information (chapter 3). The second part of the book delves into the different types of information resources (books, journals, websites, and data sets) and describes which resources you need to …

Design And Analysis Of Scalable Video Streaming Systems, Musab S. Al-Hadrusi

Wayne State University Dissertations

Despite the advancement in multimedia streaming technology, many multimedia applications are still face major challenges, including provision of Quality-of-Service (QoS), system scalability, limited resources, and cost. In this dissertation, we develop and analyze a new set of metrics based on two particular video streaming systems, namely: (1) Video-on-Demand (VOD) with video advertisements system and (2) Automated Video Surveillance System (AVS).

We address the main issues in the design of commercial VOD systems: scalability and support of video advertisements. We develop a scalable delivery framework for streaming media content with video advertisements. The delivery framework combines the benefits of stream merging …

Maximizing Resource Utilization In Video Streaming Systems, Mohammad A. Alsmirat

Wayne State University Dissertations

Video streaming has recently grown dramatically in popularity over the Internet, Cable TV, and wire-less networks. Because of the resource demanding nature of video streaming applications, maximizing resource utilization in any video streaming system is a key factor to increase the scalability and decrease the cost of the system. Resources to utilize include server bandwidth, network bandwidth, battery life in battery operated devices, and processing time in limited processing power devices. In this work, we propose new techniques to maximize the utilization of video-on-demand (VOD) server resources. In addition to that, we propose new framework to maximize the utilization of …

An Empirical Examination And Metaevaluation Of The Impact Evaluation Process, Anne Maechling Blake

Wayne State University Dissertations

This dissertation empirically examines the Guerra-Lopez (2007a) Impact Evaluation Process (IEP), which is a prescriptive program evaluation model. Since there is no generally accepted process for arriving at final judgments about the usefulness, appropriateness, effectiveness, reliability, and validity of evaluation models, this study used a combination of approaches to begin to build a body of evidence about the effectiveness of the IEP. Primarily, the study used Stufflebeam's (2011) recently revised Program Evaluations Metaevaluation Checklist to examine the model. The Checklist is based on the Joint Committee on Standards for Educational Evaluation's (2010) Program Evaluation Standards. Fitzpatrick, Sanders, & Worthen (2011) …

A Phenomenological Study To Engage African-American Youth Voice In Deliberations Regarding Their Response To Schooling, Donna Michelle Coulter

Wayne State University Dissertations

To examine disparities in education, the researcher utilized a naturalistic approach to uncover how youth think, talk, and feel about their response to schooling. Findings are based on in-depth conversations with 12 inner city African-American kids enrolled in Urban, USA middle and high schools, rarely heard from in the scholarly literature. Students conveyed a belief system that schooling was the route to upward mobility, however, their responses to academic exercises seem to suggest an indifference. Primary findings suggest that students' (a) sense of safety and family tradition were key factors of student school selection; (b) understanding of how levels of …

Practice As Pedagogy: Learning Through Participation In The Caribexams Online Community Of Practice, Kathy-Ann Daniel-Gittens

Wayne State University Dissertations

The purpose of this study was to develop community redesign strategies to support community members' participation in the CaribExams online Community of Practice and to investigate the impact of these strategies on members' participation levels and trajectories.

CaribExams online community was developed to assist out-of-school learners who were preparing to sit for the Caribbean Examinations Council's regional English exam. The redesign project was developed to address an ongoing problem of low participation by members in the online community. A second purpose of the study was to investigate and empirically validate theoretically grounded design principles based on social practice learning theory …

A Design-Based Research Study Examining The Impact Of Motivational Emailed Messages To First Year Students, Sara Elizabeth Kacin

Wayne State University Dissertations

SARA E. KACIN

May 2013

Advisor: Dr. Monica W. Tracey

Major: Instructional Technology

Degree: Doctor of Philosophy

This research study examined the effects of strategically designed motivational emails using the instructional design strategy ARCS (Keller, 1987abc) for first year students in a face to face setting. A design based research approach applying a mixed study of quantitative and qualitative research methods was taken. Quantitative and qualitative data in terms of student motivation and perceptions of the motivational emails were collected through three iterative design cycles. A multiple choice comprehensive pre test and post test were given to students to detect …

Charitable Giving: Motivations, Deterrents & Consequences, Jennifer Lawson

Wayne State University Dissertations

Charitable giving has been suggested to be beneficial to everyone involved in the activity. This study has shown charitable giving can be costly to involved participants. Motives, deterrents and outcomes of charitable giving will be discussed in this paper. Implications for future practice and study will also be discussed.

Instructional Designers' Perceptions Regarding Preparation For Practice In A Health Care Environment, Nandita S. Mani

Wayne State University Dissertations

This study utilized a multi-case, bounded case, single-site case study research design to examine how well instructional designers perceive themselves able to practice ID in health care industries. Questions central to this study focused on how instructional designers perceive their preparation to practice, usefulness of professional development organizations or affiliations in which they participated while practicing ID, both academic and non-academic curricula, and utilization of ID practices when designing and developing ID projects in health care environments.

The site selected for this study was a teaching hospital in Southeast Metropolitan Detroit, Michigan. Sampling size was limited to five instructional designers …

A Qualitative Study: Integrating Art And Science In The Environment, Deborah Naughton Mills

Wayne State University Dissertations

The study was used to develop an understanding of the nature of a creative learning experience that incorporated the foundational elements of Reggio Emilia, place-based education, and experience design. The study took place in an urban high school with eight students in an advanced placement art class. The qualitative research project revolved around the pollinator garden that the science teacher planted in the year prior to the study and the garden that was planted in the spring. Students were asked to create an art project that could withstand the Michigan climate. The science teacher lectured on elements of the pollinator …

The Effects Of Applying Authentic Learning Strategies To Develop Computational Thinking Skills In Computer Literacy Students, Wendye Dianne Mingo

Wayne State University Dissertations

This study attempts to determine if authentic learning strategies can be used to acquire knowledge of and increase motivation for computational thinking. Over 600 students enrolled in a computer literacy course participated in this study which involved completing a pretest, posttest and motivation survey. The students were divided into an experimental and control group based on class meeting day. The experimental group was given access to an authentic learning tool called COTHAULE. COTHAULE, which is an acronym that stands for Computational Thinking Authentic Learning Environment, is a website that was developed using a variety of technologies. The intellection behind COTHAULE …

Using Academic Advising To Increase Motivation And Engagement In First-Year College Students, Lisa Remsing

Wayne State University Dissertations

According to ACT Educational Services (2010), more than one-third of college freshmen will not progress to their sophomore year. Several states, including Michigan, have proposed higher education performance funding models, which directly correlate state funds to student retention and graduation rates (Jesse, 2012). As higher education suffers from diminishing resources, there is a heightened focus to increase retention and graduation rates (Tinto, 2007).

The transition from high school to college can be a traumatic time for adolescents. This age group has unique motivational needs as they adjust to an unfamiliar academic environment (Perry et al., 2005). The first year of …

Without Content: Rhetoric, American Anarchism, And The End(S) Of Radical Politics, Michael John Ristich

Wayne State University Dissertations

My study suggests there is a homology between the Platonic critique of rhetoric and the critique of anarchism made by both Marxism and liberalism. I investigate this problematic by taking up a genealogical examination of anarchism in America that begins with America's founding and concludes with a discussion of the resurgence of populist/anti-Statist rhetoric(s) in the early twenty-first century. In doing so, I argue that anarchism is a politics "without content;" it is a rhetorical politics that challenges the (re)turns to metaphysics and Marxism in the wake of poststructuralist and postmodern thought. Specifically, in light of the contemporary Tea Party …

Acidic Pericellular Ph: Effects On Proteolysis And Gene Expression As Determined In 3d Models Of Breast Carcinoma, Jennifer M. Rothberg

Wayne State University Dissertations

Among the non-cellular microenvironmental factors that contribute to malignancy of solid tumors is an acidic peritumoral pH. The first objective was to determine if an acidic extracellular pH observed in vivo (i.e., pHe 6.8) affects the activity of proteases, such as cathepsin B, that contribute to degradation of collagen IV by tumor cells when grown in biologically relevant three-dimensional cultures. At pHe 6.8 there were increases in pericellular active cysteine cathepsins and in degradation of DQ-collagen IV, which was partially blocked by a cathepsin B inhibitor. Imaging probes for active cysteine cathepsins localized to tumors in vivo. The amount of …

A Model For Designing Instructional Narratives For Adult Learners: Connecting The Dots, Debra Mary Smith

Wayne State University Dissertations

ABSTRACT

A MODEL FOR DESIGNING INSTRUCTIONAL NARRATIVES:

CONNECTING THE DOTS

by

DEBRA M. SMITH

May 2013

Advisor: Ingrid Guerra-López, Ph.D.

Major: Instructional Technology

Degree: Doctor of Philosophy

The purpose of this study was to develop a research-based model for designing and deploying instructional narratives based on principles derived from narrative theory, development theory, communication theory, learning theory and instructional design theory to enable adult learning and retention and the effective transfer of that retained learning to practice (performance contexts). Findings from these five areas were used to identify elements to inform the development of a model for the design and …

Elucidation Of The Functional Role Of Pcbp-The Cytosolic Iron Chaperone Protein Family, In Cellular Iron Homeostasis, Poorna Subramanian

Wayne State University Dissertations

Biological Role of Ferritin - Iron is essential for life and often utilized as a cofactor in many proteins. In humans, iron accumulation causes cirrhosis, arthritis, cardiomyopathy and diabetes mellitus, and it is associated with increased risk of cancer and heart disease. In contrast, decreased brain iron content results in permanent neurocognitive and motor impairment. Intracellular iron content must be maintained within a narrow range to avoid the adverse effects of iron depletion or excess, and this function is performed by the protein ferritin. Ferritins are iron storage proteins that are ubiquitously expressed in animals, plants and bacteria. They serve …

The Rigor/Relevance Framework©:Its Relationship To K-12 Student Achievement On Statewide Tests, Catherine Colagross Willoughby

Wayne State University Dissertations

ABSTRACT

THE RIGOR/RELEVANCE FRAMEWORK©:ITS RELATIONSHIP TO K-12 STUDENT ACHIEVEMENT ON STATEWIDE TESTS

by

CATHERINE COLAGROSS WILLOUGHBY

December, 2012

Advisor: Dr. Ingrid Guerra-Lopez

Major: Instructional Technology

Degree: Doctor of Philosophy

This study generated empirical evidence about the characteristics of effective professional development for K-12 teachers and explored the relationship between professional development and student achievement. This study provided evidence about whether characteristics found in past studies could also be found in the Rigor/Relevance Framework, a teaching model, used for the purpose of improving student learning through activities which are rigorous and have relevance in students' lives.

In order to fully understand …

Reading The Tea Leaves: The Media And Sino-American Rapprochement, 1963-1972, Guolin Yi

Wayne State University Dissertations

This dissertation aims to find out what role(s) the media in the United States and China played in their historic rapprochement from 1963 to 1972. In order to examine how they covered the major events that affected Sino-American relations, I select seven elite U.S. media and two Chinese official newspapers to study. These media include: the New York Times, Washington Post, Time, Newsweek, CBS, ABC, NBC, People's Daily, and Reference News,

The study is based on the assumption that media, instead of reporting the information "objectively," have the ability to affect the content they deliver and set the agenda for …

Electronic Performance Support Systems: Comparison Of Types Of Integration Levels On Performance Outcomes, Sharon A. Phillips

Wayne State University Dissertations

Selecting appropriate performance improvement interventions is a critical component of a comprehensive model of performance improvement. Intervention selection is an interconnected process involving analysis of an organization's environment, definition of the performance problem, and identification of a performance gap and identification of causal factors. When the performance gap relates to a lack of knowledge or information on the job, instructional approaches such as training have been traditionally used; however, non-instructional interventions such as electronic performance support systems (EPSS) have gained increasing attention as alternatives to training interventions.

Electronic Performance Support Systems (EPSS) use computing technology to support task performance on …

Modeling Of Mouse Eye And Errors In Ocular Parameters Affecting Refractive State, Gurinder Bawa

Wayne State University Dissertations

ABSTRACT

MODELING OF MOUSE EYE AND ERRORS IN OCULAR PARAMETERS AFFECTING REFRACTIVE STATE

by

GURINDER BAWA

September 2013

Advisor: Dr. Ivan Avrutsky

Major: Electrical Engineering

Degree: Doctor of Philosophy

Rodents eye are particularly used to study refractive error state of an eye and development of refractive eye. Genetic organization of rodents is similar to that of humans, which makes them interesting candidates to be researched upon. From rodents family mice models are encouraged over rats because of availability of genetically engineered models. Despite of extensive work that has been performed on mice and rat models, still no one is able …

The Role Of Online Social Media In The Acculturation Process Of North Korean Refugee Young Adults In South Korea, Sung Mi Han

Wayne State University Dissertations

The purpose of this study is to investigate media's influences on the acculturation of North Korean refugee young adults in South Korea, especially focusing on identifying the role of online social media. The study examined the acculturation and media patterns of the refugee young adults and found evidence that the use of South Korean media and North Korea-related media enhanced the acculturation domains of South and North Korean cultures, and therefore the utilization of both media as a whole can facilitate the pluralism model of acculturation. Specifically, a series of hierarchical multiple regressions revealed that South Korean mass media use …

Examining The Use Of Spirituality As A Form Of Social Support In Computer-Mediated Communication, Kristopher Micheal Paal

Wayne State University Dissertations

Social Information Processing Theory (Walther, 1992) suggests that individuals can develop and sustain relationships in online contexts even with limited cues present. With more individuals using computer-mediated communication (CMC) for relational processes, there is an increased need for examination of how communication is used with fewer cues present. Due to its contributions to holistic health, spirituality is a dimension of support which also necessitates increased examination as well. The present study examines how CMC can be used for the relational purposes of spiritual and social support in online communities. Messages from two separate online bereavement communities were analyzed to discover …

Mitochondrial Dna Instability In Cells Lacking Aconitase Correlates With Iron Citrate Toxicity, Muhammad A. Farooq, Tammy M. Pracheil, Zhejun Dong, Fei Xiao, Zhengchang Liu

Biological Sciences Faculty Publications

Aconitase, the second enzyme of the tricarboxylic acid cycle encoded by ACO1 in the budding yeast Saccharomyces cerevisiae, catalyzes the conversion of citrate to isocitrate. aco1 Delta results in mitochondrial DNA (mtDNA) instability. It has been proposed that Aco1 binds to mtDNA and mediates its maintenance. Here we propose an alternative mechanism to account for mtDNA loss in aco1 Delta mutant cells. We found that aco1 Delta activated the RTG pathway, resulting in increased expression of genes encoding citrate synthase. By deleting RTG1, RTG3, or genes encoding citrate synthase, mtDNA instability was prevented in aco1 Delta mutant …

Mitochondrial Dna Instability In Cells Lacking Aconitase Correlates With Iron Citrate Toxicity, Zhengchang Liu, Fei Xiao, Zhejun Dong, Tammy Pracheil, Muhammad Farooq

Biological Sciences Faculty Publications

Aconitase, the second enzyme of the tricarboxylic acid cycle encoded by ACO1 in the budding yeast Saccharomyces cerevisiae, catalyzes the conversion of citrate to isocitrate. aco1Δ results in mitochondrial DNA (mtDNA) instability. It has been proposed that Aco1 binds to mtDNA and mediates its maintenance. Here we propose an alternative mechanism to account for mtDNA loss in aco1Δ mutant cells. We found that aco1Δ activated the RTG pathway, resulting in increased expression of genes encoding citrate synthase. By deleting RTG1, RTG3, or genes encoding citrate synthase, mtDNA instability was prevented in aco1Δ mutant cells. Increased activity of citrate synthase leads …

Progress Towards Understanding Of Mechanisms Of Action Of Potent Multifunctional Disease Modifying Therapeutics For Parkinson's Disease & Investigating The Methamphetamine-Induced Striatal Microglia Activation., Mrudang M. Shah

Wayne State University Dissertations

PROGRESS TOWARDS UNDERSTANDING OF MECHANISMS OF ACTION OF POTENT MULTIFUNCTIONAL DISEASE MODIFYING

THERAPEUTICS FOR PARKINSON'S DISEASE.

by

MRUDANG MANOJKUMAR SHAH

December 2013

Advisor: Dr. Aloke Dutta

Major: Pharmaceutical Sciences

Degree: Doctor of Philosophy

Our long term goal is to design and develop potent multifunctional disease modifying therapeutics for Parkinson's disease. The objective of my dissertation was to understand the mechanisms of action of some potent small molecules (synthesized in our lab) as a disease modifying Parkinson's disease therapeutic. The objective was achieved by pursuing the following two specific aims:

1. Investigating anti-oxidant and neuroprotective effects of a lead molecule (D-512) …