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2013

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Tetab(46), A Predicted Heterodimeric Abc Transporter Conferring Tetracycline Resistance In Streptococcus Australis Isolated From The Oral Cavity, Philip J. Warburton, Lena Ciric, Avigdor Lerner, Lorna A. Seville, Adam P. Roberts, Peter Mullany, Elaine Allan Jan 2013

Tetab(46), A Predicted Heterodimeric Abc Transporter Conferring Tetracycline Resistance In Streptococcus Australis Isolated From The Oral Cavity, Philip J. Warburton, Lena Ciric, Avigdor Lerner, Lorna A. Seville, Adam P. Roberts, Peter Mullany, Elaine Allan

School of Biomedical Sciences

No abstract provided.

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Pregnancy Planning, Smoking Behaviour During Pregnancy, And Neonatal Outcome: Uk Millennium Cohort Study, Anika Flower, Jill Shawe, Judith Stephenson, Pat Doyle Jan 2013

Pregnancy Planning, Smoking Behaviour During Pregnancy, And Neonatal Outcome: Uk Millennium Cohort Study, Anika Flower, Jill Shawe, Judith Stephenson, Pat Doyle

School of Nursing and Midwifery

Abstract Background Pre-pregnancy health and care are important for the health of the future generations. Smoking during pregnancy has been well-researched and there is clear evidence of harm. But there has been little research on the health impact of planning for pregnancy. This study aims to investigate the independent effects of pregnancy planning and smoking during pregnancy on neonatal outcome. Methods This analysis made use of data from the UK Millennium Cohort Study. The study sample consisted of 18,178 singleton babies born in UK between 2000 and 2001. The neonatal outcomes of interest were low birthweight (<2.5 Kg) and pre-term birth (<37 completed weeks gestation). Logistic regression was used to estimate the association between pregnancy planning and/or smoking and neonatal outcome. Adjusted odds ratios were used to calculate population attributable risk fractions (PAFs). Results 43% of mothers did not plan their pregnancy and 34% were smoking just before and/or during pregnancy. Planners were half as likely to be smokers just before pregnancy, and more likely to give up or reduce the amount smoked if smokers. Unplanned pregnancies had 24% increased odds of low birth weight and prematurity compared to planned pregnancies (AORLBW1.24, 95% CI 1.04-1.48; AORPREM1.24, 95% CI 1.05-1.45), independent of smoking status. The odds of low birth weight for babies of mothers who were smoking just before pregnancy was 91% higher than that of mothers who were not (AORLBW1.91, 95% CI 1.56-2.34). Women who quit or reduced the amount smoked during pregnancy lowered the risk of a low birth weight baby by one third (AORLBW0.66, 95% CI 0.51-0.85) compared with women whose smoking level did not change. Smaller effects were found for prematurity. If all women planned their pregnancy and did not smoke before or during pregnancy, 30% of low birthweight and 14% of prematurity could, in theory, be avoided. Conclusions Planning a pregnancy and avoiding smoking during pregnancy has clear, independent, health benefits for babies. Quitting or reducing the amount smoked during pregnancy can reduce the risk of low birthweight.

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Plymouth Families Project Evaluation 2012, Z James Jan 2013

Plymouth Families Project Evaluation 2012, Z James

School of Law, Humanities and Social Sciences

No abstract provided.

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Plymouth Family Intervention Project Longitudinal Review: 2008-2013, Z James, T Green Jan 2013

Plymouth Family Intervention Project Longitudinal Review: 2008-2013, Z James, T Green

School of Law, Humanities and Social Sciences

No abstract provided.

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Exploring Religious Education And Health And Physical Education Key Learning Area Connections In Primary Schools., Tj Lynch Jan 2013

Exploring Religious Education And Health And Physical Education Key Learning Area Connections In Primary Schools., Tj Lynch

Plymouth Institute of Education

This study explored if connections were made by teachers and students in schools between religious education (RE) and health and physical education (HPE) key learning areas (KLA). The research was conducted within three Brisbane (Queensland, Australia) Catholic primary schools of varying enrolment size. It is argued that within Catholic education, the HPE curriculum documents are strongly connected to the RE curriculum material (Lynch 2004). The spiritual dimension of the HPE curriculum is defined in the syllabus as the “sense of connection to phenomena and unusual events beyond self and usual sensory and rational existence; a sense of place within the …

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Responses Of Marine Benthic Microalgae To Elevated Co2, V. R. Johnson, C. Brownlee, R. E.M. Rickaby, M. Graziano, M. Milazzo, J. M. Hall-Spencer Jan 2013

Responses Of Marine Benthic Microalgae To Elevated Co2, V. R. Johnson, C. Brownlee, R. E.M. Rickaby, M. Graziano, M. Milazzo, J. M. Hall-Spencer

School of Biological and Marine Sciences

No abstract provided.

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Hurricane-Driven Patterns Of Clonality In An Ecosystem Engineer: The Caribbean Coral Montastraea Annularis, Nicola L. Foster, Iliana B. Baums, Juan A. Sanchez, Claire B. Paris, Iliana Chollett, Claudia L. Agudelo, Mark J.A. Vermeij, Peter J. Mumby Jan 2013

Hurricane-Driven Patterns Of Clonality In An Ecosystem Engineer: The Caribbean Coral Montastraea Annularis, Nicola L. Foster, Iliana B. Baums, Juan A. Sanchez, Claire B. Paris, Iliana Chollett, Claudia L. Agudelo, Mark J.A. Vermeij, Peter J. Mumby

School of Biological and Marine Sciences

No abstract provided.

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A Decision Making System For Selecting Sustainable Technologies For Retail Buildings, Z Dangana, W Pan, S Goodhew Jan 2013

A Decision Making System For Selecting Sustainable Technologies For Retail Buildings, Z Dangana, W Pan, S Goodhew

School of Art, Design and Architecture

No abstract provided.

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Stakeholders Perspective On Sustainable Technology Selection To Achieve Zero Carbon Retail Buildings, Syeda Zainab, Wei Pan, Steve Goodhew, Alba Fuertes Jan 2013

Stakeholders Perspective On Sustainable Technology Selection To Achieve Zero Carbon Retail Buildings, Syeda Zainab, Wei Pan, Steve Goodhew, Alba Fuertes

School of Art, Design and Architecture

In the design and construction of sustainable retail buildings, there are various stakeholders involved with the overall aim of selecting appropriate sustainable technologies to reduce energy consumption and carbon emissions. Previous studies and literature review indicate there is no comprehensive selection process to assist stakeholders. This can be classified as a complex multi-criteria decision problem due to the high number of alternatives, potential solutions and variety of stakeholders (e.g. clients, professional advisors, end-users) with multiple, often conflicting, objectives leading in turn to the slow take-up of sustainable technologies. There is a demand for a systematic and effective evaluation tool for …

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Online And Local Television Networks: A New Pedagogy For A Changing Media., Phil Ellis, John Fitzsimons, David Hilton, Allister Gall Jan 2013

Online And Local Television Networks: A New Pedagogy For A Changing Media., Phil Ellis, John Fitzsimons, David Hilton, Allister Gall

School of Art, Design and Architecture

To investigate campus-based and local TV focused on innovative opportunities for students, employers and community groups to contribute to the design of learning pedagogies and course structures.To utilize the strong element of collaboration within and across creative courses in the UPC Partnership encouraging students to explore the medium of TV and establish new learning cultures that broaden the context of the student experience, encouraging creative work-based/related collaboration with local communities and employers.Research outcomes will enhance understanding of a fluid and dynamic growth area for a new media, new educational and employment possibilities and arts practice, which in turn will inform …

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Who Regulates The Smart Grid? : Ferc's Authority Over Demand Response Compensation In Wholesale Electricity Markets, Joel B. Eisen Jan 2013

Who Regulates The Smart Grid? : Ferc's Authority Over Demand Response Compensation In Wholesale Electricity Markets, Joel B. Eisen

San Diego Journal of Climate & Energy Law

This Article argues that Order 745 is both justified under the Federal Power Act (FPA) and important to ensure the transition to a clean energy future. A challenge to Order 745, Electric Power Supply Association v. FERC, is currently pending in the D.C. Circuit. This Article contends that Order 745 should be upheld against this challenge because it fits within FERC’s broad authority to regulate the wholesale power markets.

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Expedited Approval Of Energy Projects: Toward Assessing The Forms Of Procedural Relief, Michael B. Gerrard Jan 2013

Expedited Approval Of Energy Projects: Toward Assessing The Forms Of Procedural Relief, Michael B. Gerrard

San Diego Journal of Climate & Energy Law

This research is heading toward two further sets of questions, which may or may not be reached in the current phase of the work.

First, if certain permits or reviews can be dispensed with for certain projects, and there are few negative collateral consequences, do we need these permits and reviews at all? Every proposed project is important to someone, and arguments can almost always be mounted that a given kind of project warrants special treatment. The present inquiry may help identify some requirements that are obsolete and should not apply to anyone, and it may also help identify others …

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Harmonizing Distributed Energy And The Endangered Species Act, J. B. Ruhl Jan 2013

Harmonizing Distributed Energy And The Endangered Species Act, J. B. Ruhl

San Diego Journal of Climate & Energy Law

This Article explores ways of harmonizing distributed energy and the ESA, a goal consistent with the national policy for renewable energy conservation. Several legal practitioners and scholars have identified the ESA as a potentially significant constraint on the siting and operation of wind power facilities. The ESA has also been identified as a potential barrier to renewable energy in general, as solar power, biomass, and ocean tide and wave facilities could have their own sets of impacts triggering ESA regulation. But most of this attention has been devoted to utility-scale renewable energy, with distributed energy largely ignored or perhaps assumed …

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Waste Not, Want Not: Landfill Gas To Energy Projects, Climate Change, And The Clean Air Act, Katherine A. Trisolini Jan 2013

Waste Not, Want Not: Landfill Gas To Energy Projects, Climate Change, And The Clean Air Act, Katherine A. Trisolini

San Diego Journal of Climate & Energy Law

This Article aims to address this gap, proposing how the Rule could be amended to reduce methane generally and enhance LGTE specifically.

The sections discuss legal mechanisms to reduce landfill methane emissions and promote LGTE where appropriate, focusing on the federal Clean Air Act’s potential role in regulating landfill gas emissions. Section II explains the adverse effects of methane emissions generally and the potential benefits of reducing landfill emissions specifically. Section III describes federal emissions standards under the Clean Air Act and incentive programs for expanded use of LGTE. The discussion highlights potential conflicts between divergent means of regulating landfill …

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Climate Changes Disputes At The World Trade Organization: National Energy Policies And International Trade Liability, Nilmini Silva-Send Jan 2013

Climate Changes Disputes At The World Trade Organization: National Energy Policies And International Trade Liability, Nilmini Silva-Send

San Diego Journal of Climate & Energy Law

This Article draws attention to the different outcomes that may result when WTO law is applied to resolve climate related national energy policy disputes, signals this might send for national energy policies, and how a subtle effect of indirect state liability may arise. Several pending or unresolved complaints currently at the WTO are used to demonstrate these effects. The complaints include the greenhouse gas controversy, the wind energy subsidies complaint, and the feed-in tariffs complaint. The next section, Section II, presents the basic WTO obligations of the four countries involved in these complaints (Japan, Canada, USA, China), and ways that …

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South Africa's Electricity Crisis: The Need To Reconcile Environmental Policy Decisions With International Treaties, Brittany D. Botterill Jan 2013

South Africa's Electricity Crisis: The Need To Reconcile Environmental Policy Decisions With International Treaties, Brittany D. Botterill

San Diego Journal of Climate & Energy Law

This Comment examines whether South Africa’s treaty obligations conflict with the requirement of the country’s government to provide electricity to a burgeoning home-owning population. Section II introduces Eskom, South Africa’s largest utility company, which produces most of the electricity used in South Africa and surrounding countries. Section III discusses South Africa’s role in the Southern Africa Power Pool and the additional obligations this membership places on the country. Section IV then examines the controversial loan that South Africa received from the World Bank to assist in building the Medupi coal-fired power plant. Section V illustrates South Africa’s climate change obligations …

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The Emergence Of Natural Gas And The Need For Cooperative Federalism To Address A Big "Fracking" Problem., Joshua P. Dennis Jan 2013

The Emergence Of Natural Gas And The Need For Cooperative Federalism To Address A Big "Fracking" Problem., Joshua P. Dennis

San Diego Journal of Climate & Energy Law

This Comment explores the recent emergence of natural gas production, the hydraulic fracturing process and briefly touches on the current regulatory system that oversees its operation. I then explain why the current regulatory system is insufficient to protect individuals and the environment from hydraulic fracturing. And lastly, I argue that a form of cooperative federalism is the best approach to regulate hydraulic fracturing.

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Inverted Takotsubo Cardiomyopathy And The Fundamental Diagnostic Role Of Echocardiography, Arantza Manzanal, Lara Ruiz, Jose Madrazo, Majesh Makan, Julio Perez Jan 2013

Inverted Takotsubo Cardiomyopathy And The Fundamental Diagnostic Role Of Echocardiography, Arantza Manzanal, Lara Ruiz, Jose Madrazo, Majesh Makan, Julio Perez

The Texas Heart Institute Journal

Takotsubo cardiomyopathy is characterized by the development of transient focal wall-motion abnormalities that involve the apical and midventricular segments, in the absence of obstructive coronary artery disease. A variant, inverted takotsubo cardiomyopathy, was described in 2010. We report 3 cases in which each patient's transthoracic echocardiogram revealed the characteristic basal and midventricular segmental akinesis of this variant. This pattern is not associated with coronary artery distribution, and it therefore can be differentiated from coronary artery disease with the use of echocardiography, by evaluating the distribution and temporal changes of akinetic areas.

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Endovascular Treatment Of Acute Type B Dissection Complicating Aortic Coarctation, Seyed Ebrahim Kassaian, Kyomars Abbasi, Mehdi Mousavi, Mohammad Sahebjam Jan 2013

Endovascular Treatment Of Acute Type B Dissection Complicating Aortic Coarctation, Seyed Ebrahim Kassaian, Kyomars Abbasi, Mehdi Mousavi, Mohammad Sahebjam

The Texas Heart Institute Journal

Surgical treatment poses a high risk to patients with concomitant aortic coarctation and dissection, and an interventional approach could be an alternative. We describe the case of a 52-year-old man with a long history of untreated hypertension and aortic coarctation who emergently presented at our institution with an acute Stanford type B dissection. The patient's elevated serum creatinine level, perfusion deficit in the right lower limb, and hypertension did not respond to medical therapy, and he did not consent to surgery. By endovascular means, we used a self-expandable stent-graft to cover the entry point of the dissection; then, we deployed …

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Preventing Sudden Cardiac Death In Athletes: In Search Of Evidence-Based, Cost-Effective Screening, Paolo Angelini, Mladen I Vidovich, Christine E Lawless, Macarthur A Elayda, J Alberto Lopez, Dwayne Wolf, James T Willerson Jan 2013

Preventing Sudden Cardiac Death In Athletes: In Search Of Evidence-Based, Cost-Effective Screening, Paolo Angelini, Mladen I Vidovich, Christine E Lawless, Macarthur A Elayda, J Alberto Lopez, Dwayne Wolf, James T Willerson

The Texas Heart Institute Journal

Sudden cardiac death in athletes is a recurrent phenomenon at sporting events and during training. Recent studies have associated sudden cardiac death with such cardiovascular conditions as coronary artery anomalies, cardiomyopathies, and electrocardiographic abnormalities, most of which are screenable with modern imaging techniques. We recently inaugurated the Center for Coronary Artery Anomalies at the Texas Heart Institute, which is dedicated to preventing sudden cardiac death in the young and investigating coronary artery anomalies. There, we are conducting 2 cross-sectional studies intended to firmly establish and quantify, in a large group of individuals from a general population, risk factors for sudden …

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Early Hemodynamic And Biochemical Changes In Overloaded Swine Ventricleearly Hemodynamic And Biochemical Changes In Overloaded Swine Ventricle, Sandro Gelsomino, Fabiana Lucà, Chiara Nediani, Sandra Zecchi Orlandini, Daniele Bani, Antonio S Rubino, Attilio Renzulli, Roberto Lorusso, Andrea Consolo, Antonino Lo Cascio, Jos Maessen, Gian Franco Gensini Jan 2013

Early Hemodynamic And Biochemical Changes In Overloaded Swine Ventricleearly Hemodynamic And Biochemical Changes In Overloaded Swine Ventricle, Sandro Gelsomino, Fabiana Lucà, Chiara Nediani, Sandra Zecchi Orlandini, Daniele Bani, Antonio S Rubino, Attilio Renzulli, Roberto Lorusso, Andrea Consolo, Antonino Lo Cascio, Jos Maessen, Gian Franco Gensini

The Texas Heart Institute Journal

The present study was undertaken to investigate, in an animal model, the relationship between sarcoplasmic reticulum Ca2+-ATPase (SERCA2a) activity, phospholamban phosphorylation, acylphosphatase activity, and hemodynamic changes that occur in the early phase of pressure overload. In 54 study-group pigs, weighing 40±5 kg each, an aortic stenosis was created with a band of umbilical tape tied around the aorta; 18 sham-operated pigs formed our control group. Eight animals (6 study and 2 control) were randomly assigned to each experimental time (0.5, 3, 6, 12, 24, 48, 72, 96, and 168 hr). All indices of left ventricular function declined significantly, with a …

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Three Essays Investigating China's Coal Production Needs And Consumption Patterns., Nyakundi M. Michieka Jan 2013

Three Essays Investigating China's Coal Production Needs And Consumption Patterns., Nyakundi M. Michieka

Graduate Theses, Dissertations, and Problem Reports (ETD)

China, characterized by the world.s largest population, is one of the most rapidly growing countries and the largest consumer of energy in the world. Over the last decade, China.s consumption of total global coal has increased by 15%. Besides being the largest producer of coal, China currently consumes over 40% of the yearly total coal output. Since China.s appetite for coal is growing, it is important to understand the sources of this growth. This study investigates China.s coal consumption patterns and production needs among the various sectors in its economy. It intends to identify and model the market forces affecting …

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Essays On The Effects Of Womens Rights On Female Brain Drain., Maryam Naghsh Nejad Jan 2013

Essays On The Effects Of Womens Rights On Female Brain Drain., Maryam Naghsh Nejad

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation investigates the effects of gender discrimination, proxied by a women's rights index, on the female high-skilled migration rates relative to that of male (the female brain drain ratio). First, by developing a model of migration choice I find non-linear effects of gender discrimination on the female brain drain ratio as a result of effects of gender discrimination on both costs and benefits of migration. At low levels of women's rights, increases in the index lead to increases in the female brain drain ratio. At very low levels of women's rights, it is often prohibitively costly for females to …

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Occupational Risk Factors In Chronic Obstructive Pulmonary Disease, Bent C. Doney Jan 2013

Occupational Risk Factors In Chronic Obstructive Pulmonary Disease, Bent C. Doney

Graduate Theses, Dissertations, and Problem Reports (ETD)

Introduction: Chronic obstructive pulmonary disease (COPD) causes increased disability and mortality in the U.S. population. Approximately 15% of cases of COPD can be attributed to occupational exposure. There are gaps in the knowledge of the relationships between occupational exposure and COPD and further investigation can provide information helpful in improving COPD preventive strategies in the workplace. The objective of this project was to assess COPD prevalence in population based studies and characterize the relationship between COPD and occupational exposure.;Methods/Results: Three separate U.S. population-based cross-sectional studies of COPD were conducted. In the first study, a COPD job exposure matrix (JEM) was …

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Gas-Phase Reactions Of Methamphetamine With Hydroxyl Radicals And Ozone, Crystal D. Forester Jan 2013

Gas-Phase Reactions Of Methamphetamine With Hydroxyl Radicals And Ozone, Crystal D. Forester

Graduate Theses, Dissertations, and Problem Reports (ETD)

Gas-phase reactions involving methamphetamine, the hydroxyl radical (OH·), and ozone (O3) at (297 +/- 3) K and 1 atmosphere total pressure were investigated. A bimolecular rate constant, kOH·+methamphetamine, (960 +/- 100) x 10 -12 cm3molecule-1s-1, was measured using the relative rate technique for reactions of methamphetamine with OH·. Pseudo first-order techniques were used to measure the bimolecular rate constant, kO3+methamphetamine , (2.7 +/- 0.5) x 10-17 cm3molecule -1s-1 for reactions of methamphetamine with O 3. Product studies to determine the degradation of methamphetamine in the gasphase were conducted and the products of these reactions were identified. The positively identified methamphetamine/OH· …

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Microfluidic Impedance-Metric Biosensor For Monitoring Carbon Nanotube-Induced Epithelial Permeability, Zhouchun Huang Jan 2013

Microfluidic Impedance-Metric Biosensor For Monitoring Carbon Nanotube-Induced Epithelial Permeability, Zhouchun Huang

Graduate Theses, Dissertations, and Problem Reports (ETD)

Carbon nanomaterials, including carbon nanotubes (CNTs) gain increasing interest in commercial and biomedical applications. Adverse health effects of engineered CNTs may result from either direct exposure during production, inadvertent exposure during use of by-products, and/or release of these materials into the environment. Recent studies have shown that CNTs can induce cytotoxicity, apoptosis, DNA damage, and tumor formation in animals, suggesting their potential toxicity in humans. To address the current needs in developing in vitro cell assays for assessment of the adverse health effects of CNTs in lung respiratory, we have developed a microfluidic impedance-metric biosensor for investigation of multi-walled CNTs …

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Stress And Obesity: Facilitation Of Neuroendocrine And Autonomic Nervous System Recovery From Stress While Eating Comfort Foods?, Paula R. Prentice Jan 2013

Stress And Obesity: Facilitation Of Neuroendocrine And Autonomic Nervous System Recovery From Stress While Eating Comfort Foods?, Paula R. Prentice

Graduate Theses, Dissertations, and Problem Reports (ETD)

Obesity and dysfunctional eating are prevalent and costly concerns in the United States and throughout the world (CDC, 2007; Mathus-Vliegen et al., 2008). Research into the etiology of these conditions points to problems regulating eating, particularly during times of stress. The animal literature suggests that eating during and following stress may lead to a more immediate physiological recovery from stress (e.g., Bulwalkda et al., 2001; Pecoraro et al., 2004). The present study was designed to test this phenomenon in humans; that is, to determine if eating a favorite food immediately after stress would lead to enhanced physiological recovery from stress; …

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Systematic Analysis Of Carbon Nanotubes Toxicity In Cellular Systems, Gabrielle Rogers-Nieman Jan 2013

Systematic Analysis Of Carbon Nanotubes Toxicity In Cellular Systems, Gabrielle Rogers-Nieman

Graduate Theses, Dissertations, and Problem Reports (ETD)

As the applied use for carbon nanotubes (CNTs) increases across engineering and biomedical sectors, a clear understanding of the deleterious effects surrounding CNT-induced toxicity, namely genotoxicity, is required. Currently, the exact genotoxic mechanisms that surround CNT-induced mitotic disruption that result in aneuploidy are not completely understood. Thus, there is a need for clear mechanical models to be formulated. Herein a comprehensive overview of the nanotube toxicity is provided insisting on the aspects related to CNTs genotoxicity.;In Chapter 1, I am providing a review of the current research in the CNT-s induced toxicity. I start by defining these members of the …

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Investigating The Effect Of Humor Communication Skills Training On Pro-Social And Anti-Social Humor Styles, Cognitive Learning, Self-Efficacy, Motivation, And Humor Use, Lori E. Vela Jan 2013

Investigating The Effect Of Humor Communication Skills Training On Pro-Social And Anti-Social Humor Styles, Cognitive Learning, Self-Efficacy, Motivation, And Humor Use, Lori E. Vela

Graduate Theses, Dissertations, and Problem Reports (ETD)

Humor is an important aspect of interpersonal interactions as it is linked to the development and maintenance of relationships (Merolla, 2006). The purpose of this dissertation was to test the effect of a humor communication skills training program on the ability to minimize anti-social humor (i.e., aggressive, self-defeating) and enhance pro-social humor (i.e., affiliative, self-enhancing) in interpersonal interactions. Working from the framework of Social Cognitive Theory (Bandura, 1986, 2001), the effect of the humor skills training on self-efficacy, motivation, positive and negative humor use, and cognitive learning were also examined. Data were collected at baseline, post-training, and at a two …

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Perils And Profits: A Reexamination Of The Link Between Profitability And Safety In U.S. Aviation, Peter M. Madsen Jan 2013

Perils And Profits: A Reexamination Of The Link Between Profitability And Safety In U.S. Aviation, Peter M. Madsen

Faculty Publications

In many industries, for-profit business organizations make decisions that critically impact the safety of their employees and the public. Managers in such organizations often argue that there is no trade-off between profitability and safety because “safety is good business.” However, prior studies examining the profitability–safety relationship report inconsistent and conflicting results. In the present study, the author reexamines this issue, building on insights into managerial risk taking from the behavioral theory of the firm and hypothesizing that the slope of the profitability–safety relationship reaches an inflection point at the organizational profitability aspiration. Using data from the U.S. airline industry, the …

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