Digital Commons Network^™

From Gallantry To Apostasy: The Double Life Of Edward Herbert, Ahalya Bodasing

Dissertations and Theses

No abstract provided.

Sustaining The Lifespan Of Insurgent Groups; Three Critical Indicators To Consider, Sabrina K. Swamy

Dissertations and Theses

No abstract provided.

On The Origins Of The Modern Libertarian Legal Movement, Roger Pilon

Chapman Law Review

No abstract provided.

Identification Of Distant Drug Off-Targets By Direct Superposition Of Binding Pocket Surfaces., Marcel Schumann, Roger S Armen

College of Pharmacy Faculty Papers

Correctly predicting off-targets for a given molecular structure, which would have the ability to bind a large range of ligands, is both particularly difficult and important if they share no significant sequence or fold similarity with the respective molecular target ("distant off-targets"). A novel approach for identification of off-targets by direct superposition of protein binding pocket surfaces is presented and applied to a set of well-studied and highly relevant drug targets, including representative kinases and nuclear hormone receptors. The entire Protein Data Bank is searched for similar binding pockets and convincing distant off-target candidates were identified that share no significant …

Fibroblast Growth Factor-2 (Fgf2) And Syndecan-1 (Sdc1) Are Potential Biomarkers For Putative Circulating Cd15+/Cd30+ Cells In Poor Outcome Hodgkin Lymphoma Patients., Rajendra Gharbaran, Andre Goy, Takemi Tanaka, Jongwhan Park, Chris Kim, Nafis Hasan, Swathi Vemulapalli, Sreeja Sarojini, Madalina Tuluc, Kip Nalley, Pritish Bhattacharyya, Andrew Pecora, K Stephen Suh

College of Pharmacy Faculty Papers

BACKGROUND: High risk, unfavorable classical Hodgkin lymphoma (cHL) includes those patients with primary refractory or early relapse, and progressive disease. To improve the availability of biomarkers for this group of patients, we investigated both tumor biopsies and peripheral blood leukocytes (PBL) of untreated (chemo-naïve, CN) Nodular Sclerosis Classic Hodgkin Lymphoma (NS-cHL) patients for consistent biomarkers that can predict the outcome prior to frontline treatment.

METHODS AND MATERIALS: Bioinformatics data mining was used to generate 151 candidate biomarkers, which were screened against a library of 10 HL cell lines. Expression of FGF2 and SDC1 by CD30+ cells from HL patient samples …

Volume 25 — Peace Building, Social Transformation And Religion In Africa: Contextual Theological Reflection, The Ecumencial Association Of Nigerian Theologians

Bulletin of Ecumenical Theology

No abstract provided.

Electric Municipalization In The City Of Boulder: Successful Greening Or Path To Bankruptcy?, Kathryn C. Browning

CMC Senior Theses

Climate change will result in variable – but undeniably severe – changes to our natural world. These changes will lead to extreme human and ecosystem consequences if climate change is not mitigated effectively, efficiently, and rapidly. Increasing the use of renewable energies around the world is seen as one of the most effective and promising mitigation strategies. Several communities around the United States have recently denounced publicly their electrical utilities for their failure to offer the choice to increase the percentage of energy that comes from renewable sources. A growing number are taking action to work with – or sometimes …

Fall 2013

Metro Denver Dental Society Articulator Magazine

The MDDS Articulator magazine has been serving as the voice for Denver's dental community for over 100 years.

Distributed to approximately 2,000 dental professionals quarterly, the Articulator features local news, industry trends, practice management guidance, data-driven research and more. The award-winning publication is available to member dentists in both print and digital forms.

Issues include cover and feature articles alongside regular columns with regional news impacting the Metro Denver membership including editorial and perspectives columns, legal, association activities, component news, continuing education opportunities, and classifieds.

Winter 2013

Metro Denver Dental Society Articulator Magazine

The MDDS Articulator magazine has been serving as the voice for Denver's dental community for over 100 years.

Distributed to approximately 2,000 dental professionals quarterly, the Articulator features local news, industry trends, practice management guidance, data-driven research and more. The award-winning publication is available to member dentists in both print and digital forms.

Issues include cover and feature articles alongside regular columns with regional news impacting the Metro Denver membership including editorial and perspectives columns, legal, association activities, component news, continuing education opportunities, and classifieds.

The Mobile Health Revolution?, Nathan Cortez

Faculty Journal Articles and Book Chapters

Rarely does a class of technologies excite physicians, patients, financeers, gadgeteers, and policymakers alike. But mobile health — the use of mobile devices like smartphones and tablets for health or medical purposes — has captured our collective imagination. Observers predict that mobile health, also referred to as “mHealth” or “medical apps,” can save millions of lives, billions in spending, and democratize access to health care. Proponents argue that mobile health technologies will transform the ways in which we deliver, consume, measure, and pay for care; disrupting our sclerotic health care system.

This Article evaluates mobile health and its many ambitions. …

A Community Of Procedure Scholars: Teaching Procedure And The Legal Academy, Elizabeth G. Thornburg, Erik S. Knutsen, Carla Crifo, Camille Cameron

Faculty Journal Articles and Book Chapters

This article asks whether the way in which procedure is taught has an impact on the extent and accomplishments of a scholarly community of proceduralists. Not surprisingly, we find a strong correlation between the placement of procedure as a required course in an academic context and the resulting body of scholars and scholarship. Those countries in which more civil procedure is taught as part of a university degree — and in which procedure is recognized as a legitimate academic subject — have larger scholarly communities, a larger and broader corpus of works analyzing procedural issues, and a richer web of …

Influence Of Removal Sampling Of Small Mammals On Abundance And Diversity Attributes: Scientific Implications, Thomas P. Sullivan, Druscilla S. Sullivan

Human–Wildlife Interactions

Terrestrial small mammals occupy a variety of temperate and boreal forests in North America and Eurasia and contribute to biodiversity within these ecosystems. Researchers commonly use a variation of removal trapping to sample small-mammal populations and communities in these systems. However, it is not known if recurrent removal sampling might bias abundance estimates or alter the very populations under study. We addressed 2 questions: (1) are estimates of population size and species richness and diversity gained from removal trapping different from those based on live-trapping? and (2) what residual impact does removal trapping have on small-mammal populations and communities, as …

Consumption Of Whole Cottonseed By White-Tailed Deer And Nontarget Species, Benjamin D. Taylor, Eddie Lyons, Dale Rollins, Cody B. Scott, James E. Huston, Charles A. Taylor

Human–Wildlife Interactions

Supplementing diets of white-tailed deer (Odocoileus virginianus) with pelleted rations is an increasingly common practice aimed at increasing deer antler size on rangelands in Texas. Feed loss to consumption by various nontarget species (e.g., raccoons [Procyon lotor] and feral pigs [Sus scrofa]) raises both ecological and economic concerns. Whole cottonseed is a feedstuff that may afford a more targeted supplemental feeding effort. Accordingly, we determined: (1) consumption rates of whole cottonseed by feral pigs and raccoons in captivity; and (2) species visitation at feed sites and preference for whole cottonseed relative to whole corn …

Toward An Understanding Of Beaver Management As Human And Beaver Densities Increase, William F. Siemer, Sandra A. Jonker, Daniel J. Decker, John F. Organ

Human–Wildlife Interactions

Estimates of beaver (Castor canadensis) density play an important role in wildlife managers’ decisions about beaver population management, because managers anticipate higher incidence of problem complaints when a beaver population increases. To manage the impacts of beavers in an urbanizing landscape, managers need better information on changes in stakeholder beliefs and attitudes as beaver and human densities reach high levels. We conducted additional analysis of data collected in 2002 through mail surveys of residents in New York and Massachusetts to test hypothesized relationships between beaver density and damage experience, attitudes toward beavers, and norms about beaver management actions. …

Potential Role Of Wildlife In Pathogenic Contamination Of Fresh Produce, Jeff A. Langholz, Michele T. Jay-Russell

Human–Wildlife Interactions

The safety of fresh produce is an important concern in the United States, especially in the wake of recent national foodborne illness outbreaks. The agricultural industry has implemented steps to enhance food safety along the entire farm-to-fork supply chain. This includes on-farm measures to exclude wildlife and to remove its habitat in and around fields. Farmers and others from across the United States have expressed concern about the ecological consequences and uncertain food safety benefits of such practices. This article reviews the scientific rationale behind management of wildlife and its habitat as part of good agriculture practices for enhancing food …

In The News, Joe N. Caudell

Human–Wildlife Interactions

No abstract provided.

Livestock Predation By Common Leopard In Binsar Wildlife Sanctuary, India: Human-Wildlife Conflicts And Conservation Issues, Chandra Prakash Kala, Kishor Kumar Kothari

Human–Wildlife Interactions

We investigate livestock predation by the common leopard (Panthera pardus) and emerging conflicts between this species, local people, and wildlife authorities at the Binsar Wildlife Sanctuary in the Himalayan region of India. We scrutinized secondary data that were collected by wildlife authorities; we also conducted informal interviews of villagers living within sanctuary, and wildlife staff to understand various human–leopard conflicts. Leopard density was approximately 0.33/km2 in the sanctuary. Leopards killed 1,763 domestic animals, about 90% of which were cattle, during a 14-year period. Within the sanctuary, leopards killed 1 person and injured 9 others. This high depredation rate …

Vitals Rates And Seasonal Movements Of Two Isolated Greater Sage-Grouse Populations In Utah's West Desert, Jason D. Robinson, Terry A. Messmer

Human–Wildlife Interactions

Declines in greater sage-grouse (Centrocercus urophasianus; hereafter, sage-grouse) populations in Utah over the last century parallel range-wide trends. However, little is known about the ecology of sage-grouse populations that inhabit Utah’s naturally fragmented habitats. Utah’s West Desert sage-grouse populations occupy sagebrush (Artemisia spp.) habitats that are geographically separated by the Great Salt Lake, and largely confined to the Sheeprock and Deep Creek watersheds. From 2005 to 2006, we monitored sage-grouse that were radio-collared in each watershed to determine the factors affecting the vital rates in these isolated populations. Livestock grazing by domestic cattle was the dominate land use, …

Improving Internet Security Through Information Disclosure: A Field Quasi-Experiment, Qian Tang, Leigh L. Linden, John S. Quarterman, Andrew B. Whinston

Research Collection School Of Computing and Information Systems

Cybersecurity is a national priority in this big data era. Because of negative externalities and the resulting lack of economic incentives, companies often underinvest in security controls, despite government and industry recommendations. Although many existing studies on security have explored technical solutions, only a few have looked at the economic motivations. To fill the gap, we propose an approach to increase the incentives of organizations to address security problems. Specifically, we utilize and process existing security vulnerability data, derive explicit security performance information, and disclose the information as feedback to organizations and the public. We regularly release information on the …

Information Economics And Competitive Strategy, Eric K. Clemons, Kim Huat Goh, Robert John Kauffman, Thomas A. Weber

Research Collection School Of Computing and Information Systems

This Special Issue represents the revised and expanded best papers from the TwentyFifth Anniversary Symposium on Competitive Strategy, Economics and Information Systems held at the 2013 Hawaii International Conference on System Sciences and the related conference mini-track. It also represents 25 years of continuing progress and evolution in the field, and many years of a pioneering partnership between the Journal of Management Information Systems and the field of information economics and competitive strategy. JMIS was perhaps the first academic venue to welcome the field, predating the Workshop on Information Systems and Economics (WISE), and has provided a welcome home as …

Dignity, History, And Religious-Group Rights, Frederick Mark Gedicks

Faculty Scholarship

No abstract provided.

Using Meta-Ethnography To Understand The Emotional Impact Of Caring For People With Increasing Cognitive Impairment., Jane Grose, Julia Frost, Janet Richardson, Heather Skirton

School of Nursing and Midwifery

The majority of people with degenerative neurological conditions are cared for within their own families. Cognitive impairment can be a significant and increasing symptom of these conditions. In this article we report how a team of experienced researchers carried out a meta-ethnography of qualitative research articles focusing on the impact of caring for a loved one with cognitive impairment. We followed the seven-step process outlined by Noblit and Hare. Synthesized findings from 31 papers suggest emotional impact is complex and uncertain and varies from day to day. The benefit of using meta-ethnography is that the results represent a larger sample …

Influence Of Cervitec Gel On Periodontal Health Of Patients Wearing Fixed Orthodontic Appliances, Burcu Özdemir, Ahu Uraz, Duygu İşcan, Şeyma Bozkurt, Burcu Baloş Tuncer, Doruk Engin, Selcen Pehlivan, Hakan İşcan

Journal of Dental Sciences

Abstract Background/purpose This double-blinded randomized placebo-controlled study aimed to evaluate the efficacy of 0.2% chlorhexidine containing Cervitec gel on periodontal health during orthodontic treatment. Materials and methods Twenty-five patients undergoing fixed orthodontic treatment were randomly assigned to the Cervitec ( n = 13) or control ( n = 12) groups. After clinical examination at first visit, all patients received professional prophylaxis, and 2 weeks later baseline (B) evaluations are performed. Later, oral hygiene procedures were refrained for 3 days until Day 0, during which the participants in the Cervitec group were instructed to brush with standard toothpaste (ST) (1 × …

Green Technology: Legal, Ethical, And Moral Considerations, Notre Dame Journal Of Law, Ethics & Public Policy Editors

Notre Dame Journal of Law, Ethics & Public Policy

No abstract provided.

Achieving Climate Protection: Fostering An Essential Focus On Human Rights And Human Impacts, Ross C. Anderson, Patrick A. Thronson

Notre Dame Journal of Law, Ethics & Public Policy

No abstract provided.

Faith Over Fear: A Lesson For The Nation From American Agriculture, Tom Vilsack

Notre Dame Journal of Law, Ethics & Public Policy

No abstract provided.

Breaking Up Is Hard To Do: American Exceptionalism And The Transition To A Renewable Energy Future, Andrew Askland

Notre Dame Journal of Law, Ethics & Public Policy

No abstract provided.

A Greener Shade Of Blue: Technology And The Shale Revolution, Ross H. Pifer

Notre Dame Journal of Law, Ethics & Public Policy

No abstract provided.

Changing The Climate For Prosperity, David Foster

Notre Dame Journal of Law, Ethics & Public Policy

No abstract provided.

Institutionalizing Sustainability: Implementation Of Executive Order 13,514 And Its Impact On The Environmental, Economic, And Social Performance Of Pacific Northwest National Laboratory, Sarah Widder

Notre Dame Journal of Law, Ethics & Public Policy

No abstract provided.