Digital Commons Network^™

Filling In The Holes In Whistleblower Protection Systems: Lessons From The Hanford Council Experience, Jonathan Brock

Seattle Journal for Social Justice

No abstract provided.

The Money Or The Media? Lessons From Contrasting Developments In Us And Australian Whistleblowing Laws, Terry Morehead Dworkin, A.J. Brown

Seattle Journal for Social Justice

No abstract provided.

An Inconsistent Invitation: Am I Invited To Be A Party? How Not Affording Party Status To Youth In Washington Dependency Hearings Can Be A Violation Of Due Process, Laura Baird

Seattle Journal for Social Justice

No abstract provided.

Stymieing Controversy Over Generic Top-Level Domains (Gtlds) And Other Internet Governance Decisions With Content Neutrality, Nafees Uddin

Seattle Journal for Social Justice

No abstract provided.

The Future Of Transit In West Virginia, Diana Long, Benjamin L. Blandford, Peter J. Dailey, Sinaya Dayan, Justin Matthews, Kent Sowards

Reports with Contribution from KTC Researchers

No abstract provided.

Ripples Against The Other Shore: The Impact Of Trauma Exposure On The Immigration Process Through Adjudicators, Kate Aschenbrenner

Michigan Journal of Race and Law

Immigration is currently a hot topic; discussion of immigration reform and the problems in our current system appear in the news virtually every day. There is widespread consensus that our current immigration system is “broken,” but there is little agreement on why and even less on what should be done to fix it. These are difficult and important questions, involving many complex interrelated factors. While I do not hope and cannot aim to answer them completely in this Article, I will argue that in doing so we must consider an often overlooked and generally understudied issue: the effects of trauma …

Pathways To Cyber Bullying From Bystander To Participant: Secondary School Students’ Perspectives, Michele L. Siderman

Dissertations

The author conducted a qualitative analysis of student artifacts to explore the pathway and experiences of students who had never bullied in the traditional sense but had cyber bullied through the use of social networking sites. In addition, the author explored students’ understanding of the difference between traditional and cyber bullying and their perceptions of the victim receiving the online bullying messages. A transcendental phenomenological approach was employed. The student artifacts analyzed were assignments from a required ninth grade character education class, which included a self-reflective survey, journals, a six-paragraph paper, and an online photo story project.

Results indicated that …

Efficacy Of Homoeopathic Treatment For Diabetic Distal Symmetric Polyneuropathy: A Multicentric Randomised Double-Blind Placebo-Controlled Clinical Trial, Raj Manchanda, Bindu Sharma, Pritha Mehra

Indian Journal of Research in Homoeopathy

Background: There are limitations in the management of Diabetic Distal Symmetric Polyneuropathy (DDSP) in conventional system but in Homoeopathy the research studies have shown positive results. These studies were not robust enough to prove the efficacy of individualized homoeopathy, thus this protocol has been developed to assess the efficacy of these individualized homoeopathic drugs in this disease. Material and Methods: It shall be a double blind randomised placebo controlled clinical trial. On the basis of earlier observational studies and repertorial anamnesis of DDSP symptoms, 15 homoeopathic medicines have been identified. The validated scales are being used for evaluating the outcomes …

Homoeopathic Management Of Attention Deficit Hyperactivity Disorder: A Randomised Placebo-Controlled Pilot Trial, Praveen Oberai, S Gopinadhan, Roja Varanasi, Alok Mishra, Vikram Singh, Chaturbhuja Nayak

Indian Journal of Research in Homoeopathy

Objective: To evaluate the usefulness of individualised homoeopathic medicines in treatment of Attention Deficit Hyperactivity Disorder (ADHD). Design: Randomised placebo-controlled single-blind pilot trial. Setting: Central Research Institute (Homoeopathy), Kottayam, Kerala, India from June 2009 to November 2011. Participants: Children aged 6-15 years meeting the Diagnostic Statistical Manual of mental disorders (DSM-IV) criteria for ADHD. Interventions: A total of 61 patients (Homoeopathy = 30, placebo = 31) were randomised to receive either individualised homoeopathic medicine in fifty millesimal (LM) potency or placebo for a period of one year. Outcome measures: Conner′s Parent Rating Scale-Revised: Short (CPRS-R (S)), Clinical Global Impression-Severity Scale …

Preliminary Study To Evaluate Analgesic And Behavioural Effects Of Lycopodium Clavatum In Experimental Animals, Echur Sundaram, Kushal Singh, Pratap Reddy, Sunil Kumar, Kainikkara Nair, Anil Khurana, Hari Singh, Chaturbhuja Nayak

Indian Journal of Research in Homoeopathy

Background and Aim: In Homoeopathy, the drug Lycopodium clavatum is prescribed for digestive upset, inflammations of urinary organs and dermal problems, but not for the treatment of central nervous system disorders unlike its use in traditional and folk medicine for central nervous system conditions. The present study was, therefore, undertaken with an aim to explore the possible analgesic and behavioural activities of the homoeopathic formulations of Lycopodium clavatum in animal models. Material and Methods: Wistar albino rats (120-140 g) of either sex were used to evaluate analgesic effect by using hot plate, ice plate and Randall-Selitto tests and behavioural effect …

Molecular Characterization Of The Freshwater Snail Physella Acuta, Journey R. Nolan

Biology ETDs

Current insights into general animal biology, including immune function, are derived mostly from a few model organisms, a necessity imposed by effort required for in-depth studies. Modern next-generation sequencing (NGS) enables genomics-level investigations to test whether specific aspects of biology are general or unique across animal phylogeny. Meaningful comparisons require thorough identification of phylogenetically-relevant species. To provide a touchstone for Biomphalaria glabrata, a freshwater snail that is a major study model for invertebrate immunity, physid snails (Physidae; Hygrophila; Panpulmonata; Gastropoda; Mollusca) will be developed as a model for comparative immunogenomics. Chapter 1 introduces current research capabilities and details the rationale …

Designing The Tangible Experience Of Interactive Memories, Miguel Angel Cardona Jr

Theses

The process for memory keeping in the digital age has become easier, immediate, and more efficient thanks to the advent of sophisticated pocket-sized toolsets that can capture everyday experiences.

Consumer-level photo and video recording products are introduced regularly and boast more fidelity, faster speeds, and greater control than their predecessors. More often than not, these expanding feature sets do not properly serve all of their users' needs.

While the technology exists to allow for a near-complete record of one's life to be made through the use of sensors and storage media, problems involve how best to meaningfully learn from and …

Molecular Dynamics Simulations Using Advanced Sampling And Polarizable Force Fields, Tugba Kucukkal

All Dissertations

Molecular dynamics (MD) simulations were carried out for aqueous dipeptides, water over self-assembled monolayer (SAM) surfaces, and the nicotinic acetylcholine receptor (nAChR) ion channel. The main goal is to use advanced methods to increase the accuracy of molecular dynamics simulations while seeking solutions to problems relevant to chemistry, biophysics and materials science. In addition, activation energies of several cyclodimerization reactions were studied quantum mechanically. The simulations of the aqueous dipeptides and SAM surfaces involve modeling and detailed analysis of interfacial water, which is of interest to a range of fields from biology to materials science. For example, water has a …

Three Essays Evaluating Health Impacts Of The National School Lunch Program, Janet Peckham

All Dissertations

This research focuses on the health impacts of participation in the National School Lunch Program, a program providing free and reduced-cost lunches for income-eligible students and minimally subsidizing lunches for income-ineligible students. In the past decade, increasing incidence of childhood obesity, particularly among low-income individuals has drawn scrutiny over the NSLP's role in the health of student-aged children.

The first chapter introduces the reader to the NSLP, providing a history of the program since its inception at the turn of the 20th century and addressing current issues in the economic literature regarding health impacts of program participation. The second chapter …

A Characterization Of Gold Nanoparticle Uptake By Mammalian Cells, Thomas Garner

All Dissertations

Over the past decade, there has been an exponential growth in products and applications that utilize nanotechnology, as these materials present exciting opportunities for the development of new products, enhancement of existing products, and the evolution of innovative procedures. However, this recent growth has occurred in the absence of detailed knowledge concerning the interactions of nanoparticles with biological systems. Nanoparticles must usually be bioavailable in order to elicit a biological response, and to reach an active site they must usually cross a membrane. As a result, cell culture studies have proven to be beneficial and are generally one of the …

Building The Science Of Healthcare Public Reporting: Integrating Anecdotal Information To Enhance Sensemaking, Kapil Chalil Madathil

All Dissertations

Anecdotal information about a healthcare consumers' interaction with care providers and hospital facilities is becoming increasingly available to the public in the form of YouTube videos and as discussion posts on peer-support groups. This form of information can potentially jeopardize the utility of reports generated by Federal entities as it potentially diverts consumer attention from more reliable measures of quality. This dissertation investigates how a health consumer's choice of care is influenced by anecdotal information on the care process available on YouTube. This research then investigates the effect of information presentation methods such as narratives and active engagement with quality …

Preferences Are Public Rights, Brook E. Gotberg

Faculty Publications

In the wake of the Supreme Court’s decision in Stern v. Marshall, there is widespread uncertainty as to what other proceedings may constitutionally fall within a bankruptcy court’s core jurisdiction. Supreme Court jurisprudence has been cryptic regarding the constitutional limitations of non-Article III courts, but the Court has identified a "public rights exception" to the general rule that the judicial power must be exercised only by judges with life tenure and salary protection. This public rights exception has not yet been explicitly extended to a bankruptcy proceeding, but the reasoning of the Court strongly suggests that a trustee’s motion to …

A Case Study Investigating How Art Education Fosters Collaboration In An Urban Environment Through The Lens Of Public Pedagogy, Tracy Fox

Art Education Projects

This case study examines how one particular after-school arts program in an urban environment bridges the gap between a university campus and the community it serves, creating opportunities for collaboration via the arts. The study was conducted at a community center run by Buffalo State.

Over the course of the study, ten interviews were conducted with a variety of people connected to the Community Arts Center’s (CAC) arts programs, including partners in the public arts initiative. The data was collected and analyzed over the course of eight weeks through the lens of Henry Giroux’s public pedagogy, which focuses on educational …

Qualitative Action Research On The Benefits Of Adding Humor And Aspects Of Play In An Elementary Art Education Classroom With Sixth Graders, Kelly Macagnone

Art Education Projects

This qualitative action research study explored the benefits of using humor and aspects of play as teaching strategies in the art classroom. This study was conducted in a small Catholic elementary school located in Western New York. One sixth grade class, composed of nine students, participated in this study. Data was collected and analyzed a period of ten weeks. Conducted through the theory of constructivism, students were engaged and encouraged to construct deep understandings of important concepts in the art classroom through the tools of humor and play. My focus was how the students’ perceived humor and play in the …

Phosphate Esters, Thiophosphate Esters And Metal Thiophosphates As Lubricant Additives, David W. Johnson, John E. Hils

Chemistry Faculty Publications

Phosphate esters, thiophosphate esters and metal thiophosphates have been used as lubricant additives for over 50 years. While their use has been extensive, a detailed knowledge of how they work has been a much more recent development. In this paper, the use of phosphate esters and thiophosphate esters as anti-wear or extreme pressure additives is reviewed with an emphasis on their mechanism of action. The review includes the use of alkyl phosphates, triaryl phosphates and metal containing thiophosphate esters. The mechanisms of these materials interacting with a range of iron and steel based bearing material are examined.

Membrane-Protein Dynamics: New Perspectives In Fcepsilonri Signaling Through Single Particle Tracking, Patrick J. Cutler

Biomedical Sciences ETDs

Under physiological conditions IgE binds to its high affinity receptor, FcεRI. The aggregation of IgE-FcεRI by crosslinker initiates intracellular signaling resulting in the release of histamines and other cellular mediators that are the basis for allergic disease. In the field of IgE-FcεRI, receptor immobilization was thought to trigger signaling. Recent single particle tracking (SPT) experiments presented evidence supporting the hypothesis that small mobile aggregates are signaling competent. SPT is an important method for investigating spatio-temporal relationships at the subcellular level. New SPT tools are necessary to adequately investigate this hypothesis. The studies presented here both develop and apply tools for …

Safety Of Botulinum Toxin For Dysphagia In Oculopharyngeal Muscular Dystrophy, Sarah Youssof

Biomedical Sciences ETDs

Despite multiple studies reporting marked benefit of botulinum toxin (BTX) for treatment of cricopharyngeal dysphagia, little is known about its safety for this indication. We examined the safety of cricopharyngeal BTX for dysphagia in oculopharyngeal muscular dystrophy (OPMD). We reviewed records of patients with OPMD who received cricopharyngeal BTX. Twenty-four patients underwent 66 procedures. Overall adverse event frequency was 44%. The most common adverse events were dysphonia (24%) and worsened dysphagia (14%). Logistic regression demonstrated that dose was a significant predictor of worsened dysphagia (P=0.036) and of the composite event of dysphonia or worsened dysphagia (P=0.009). There was a non-significant …

Utah Red Raspberry Jam: The Effects Of Formulation, Heating, And Time On Color, Flavor, Texture, And Antioxidant Capacity, Jennifer Leigh Chase

Theses and Dissertations

The amount and type of antioxidants present in raspberries is dependent upon cultivar, ripeness, and growing conditions. Previous research on raspberry jam has reported some color, antioxidant, and flavor loss after processing and storage, though it is unknown to what extent similar changes will occur in raspberries grown in Utah. Sugar concentration and heating temperature as well as storage time were evaluated in an effort to maximize color retention, flavor, antioxidant content, shelf life, and consumer acceptance of Utah-grown raspberry jam. Four types of jams were processed in two batches each: low-sugar (40-42 Brix) and typical sugar (65-68 Brix) at …

Social Regulation Of Male Reproductive Plasticity In An African Cichlid Fish, Karen P. Maruska, Russell D. Fernald

Faculty Publications

Social interactions with the outcome of a position in a dominance hierarchy can have profound effects on reproductive behavior and physiology, requiring animals to integrate environmental information with their internal physiological state; but how is salient information from the animal's dynamic social environment transformed into adaptive behavioral, physiological, and molecular-level changes? The African cichlid fish, Astatotilapia burtoni, is ideally suited to understand socially controlled reproductive plasticity because activity of the male reproductive (brainpituitary gonad) axis is tightly linked to social status. Males form hierarchies in which a small percentage of brightly colored dominant individuals have an active reproductive axis, defend …

Authors' Response To Commentaries On 'Physical Activity Does Not Influence Obesity Risk', Amy Luke, Richard S. Cooper

Faculty Publications

No abstract provided.

Physical Activity Does Not Influence Obesity Risk: Time To Clarify The Public Health Message, Amy Luke, Richard S. Cooper

Faculty Publications

No abstract provided.

Area-Wide Management Of Aedes Albopictus. Part 2: Gauging The Efficacy Of Traditional Integrated Pest Control Measures Against Urban Container Mosquitoes, Dina M. Fonseca, Isik Unlu, Taryn Crepeau, Ary Farajollahi, Sean P. Healy, Kristen Bartlett-Healy, Daniel Strickman, Randy Gaugler, George Hamilton, Daniel Kline, Gary G. Clark

Faculty Publications

Background: Aedes (Stegomyia) albopictus (Skuse) is an important disease vector and biting nuisance. During the 2009 active season, six ∼1000-parcel sites were studied, three in urban and three in suburban areas of New Jersey, United States, to examine the efficacy of standard integrated urban mosquito control strategies applied area wide. Active source reduction, larviciding, adulticiding and public education (source reduction through education) were implemented in one site in each county, an education-only approach was developed in a second site and a third site was used as an untreated experimental control. Populations were surveyed weekly with BG-Sentinel traps and ovitraps. Results: …

Formin-Based Control Of The Actin Cytoskeleton During Cytokinesis, K. Adam Bohnert, Alaina H. Willet, David R. Kovar, Kathleen L. Gould

Faculty Publications

Cytokinesis, the terminal event in the canonical cell cycle, physically separates daughter cells following mitosis. For cleavage to occur in many eukaryotes, a cytokinetic ring must assemble and constrict between divided genomes. Although dozens of different molecules localize to and participate within the cytokinetic ring, the core machinery comprises linear actin filaments. Accordingly, formins, which nucleate and elongate F-actin (filamentous actin) for the cytokinetic ring, are required for cytokinesis in diverse species. In the present article, we discuss specific modes of formin-based actin regulation during cell division and highlight emerging mechanisms and questions on this topic. © 2013 Biochemical Society.

Evaluation Of Hand-Held Meters For Determination Of Hemolymph Lactate And Protein Concentrations In Red Swamp Crayfish Procambarus Clarkii, Christopher P. Bonvillain, D. Allen Rutherford, William E. Kelso, Christopher C. Green

Faculty Publications

We evaluated the accuracy of an Accutrend® lactate meter and a Reichert® Vet 360 temperature compensated refractometer for determining red swamp crayfish Procambarus clarkii (Girard, 1852) hemolymph lactate and protein concentrations, with results compared to measurements obtained from spectrophotometric analyses. Results from the lactate meter (R2 = 0.926) and refractometer (R2 = 0.830) both demonstrated strong relationships with spectrophotometer measurements, indicating that these instruments provide rapid, reliable, and economical methods for determining crayfish hemolymph lactate and protein concentrations. Both meters can provide on-site information to commercial crayfish farmers and processors to assess crayfish health and stress levels, and can also …

Labrad : Vol 39, Issue 2 - December 2013, Aga Khan University Hospital, Karachi

LABRAD - Departments of Pathology & Laboratory Medicine and Radiology Archives

• Diagnosis of Inborn Errors of Metabolism in Pakistan
• Inherited Metabolic Disorders-Presenting as Metabolic Emergencies
• Role of Biochemical Genetics Laboratary in Evaluation of IEM
• Amino Acid Chromatography for the Diagnosis of Inborn Error of Metabolism
• Polymorphism in Methylenetetrahydrofolate Reductase (MTHFR) Gene
• Diagnosis of Tyrosinemia Type I
• Congential Hypothyroidism
• Congential Adrenal Hyperplasia, An Insight of Laboratory
• Inaugration Ceremony of Section of biochemical Genetics Laboratory