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Detecting Well-Being Via Computerized Content Analysis Of Brief Diary Entries, William Tov, Kok Leong Ng, Han Lin, Lin Qiu

Research Collection School of Social Sciences

Two studies evaluated the correspondence between self-reported well-being and codings of emotion and life content by the Linguistic Inquiry and Word Count (LIWC; Pennebaker, Booth, & Francis, 2011). Open-ended diary responses were collected from 206 participants daily for 3 weeks (Study 1) and from 139 participants twice a week for 8 weeks (Study 2). LIWC negative emotion consistently correlated with self-reported negative emotion. LIWC positive emotion correlated with self-reported positive emotion in Study 1 but not in Study 2. No correlations were observed with global life satisfaction. Using a co-occurrence coding method to combine LIWC emotion codings with life-content codings, …

Radiogenic Second Cancer Risk Differences In Female Hodgkin Lymphoma Patients Treated With Proton Versus Photon Radiotherapies, Kenneth L. Homann

Dissertations and Theses (Open Access)

Hodgkin Lymphoma (HL) is the most common cancer diagnosis of young adults in the United States. Advances in curative treatments for HL, including the use of photon radiation therapy (RT) techniques, have increased 10 year survival rates to approximately 90% among young patients. These RT treatments, however, contribute to an increased incidence of radiogenic second cancer (RSC) formation to the healthy tissue surrounding the tumor volume relative to the general population. These RSCs are the leading cause of death among long-term HL survivors. Proton therapy has been shown to reduce the therapeutic dose, and therefore, the risk of developing a …

Ventral Tegmental Area Neuronal Responses To Methylphenidate Correlated To Behavioral Responses Of Adolescent And Adult Rats, Zachary Jones

Dissertations and Theses (Open Access)

Methylphenidate (MPD) is a psychostimulant used in the treat treatment of attention deficit hyperactivity disorder and more recently is being used as a cognitive enhancement and recreational drug. Its therapeutic effects are not fully understood, nor are the long term effects of the drug on brain development. The ventral tegmental area (VTA) is a site of psychostimulant action thought to be involved in behavioral sensitization. The aim of the this study was to first determine if there are differences in neuronal responses between individuals, with respect to neuronal firing patterns in the ventral tegmental area (VTA), and whether these differences …

C-Jun N-Terminal Kinases Regulate Adenovirus-Mediated Autophagy And Antigen Presentation, Sarah R. Klein

Dissertations and Theses (Open Access)

Targeted immunotherapy with recombinant, oncolytic adenoviruses is under investigation for the treatment of cancer. Evidence indicates adenoviruses induce autophagy that is required for oncolysis, but the molecular regulation of autophagy in infected cells remains under investigation. Our data suggested the canonical pathway regulating starvation-induced autophagy was not implemented in adenovirus-induced autophagy; however, adenovirus infection triggered phosphorylation of c-Jun N-terminal kinases (JNK) that was essential for autophagy. Adenoviral replication within the host cell elicited JNK pathway activation leading to B cell lymphoma-2 (Bcl-2) phosphorylation. JNK-dependent Bcl-2 phosphorylation stimulated the dissociation of Bcl-2/beclin 1 heterodimers, enabling beclin 1 to initiate autophagy. Moreover, …

Basis For Targeting Met Activation Mediated Resistance To Pi3k Inhibition In Breast Cancer, Ana M. Gonzalez-Angulo

Dissertations and Theses (Open Access)

The identification of resistance mechanisms to emerging therapies, such as those targeting the PI3K pathway and the MET receptor, has the potential to benefit a significant number of patients with breast cancer. In this study we hypothesized that concurrent aberrations in PI3K and MET will render breast cancers resistant to therapies targeting each pathway, and that combination therapy targeting the PI3K and MET pathway will optimize therapy-effect by preventing the acquisition of resistance.

We analyzed cMET and phospho-cMET levels in 257 breast cancer samples and found that high levels of both the proteins were seen in all breast cancer subtypes, …

Neural Correlates Of Audiovisual Speech Perception In Aphasia And Healthy Aging, Sarah H. Baum

Dissertations and Theses (Open Access)

Understanding speech in face-to-face conversation utilizes the integration of multiple pieces of information, most importantly the auditory vocal sounds and visual lip movements. Prior studies of the neural underpinnings of audiovisual integration in the brain have provided converging evidence to suggest that neurons within the left superior temporal sulcus (STS) provide a critical neural hub for the integration of auditory and visual information in speech. While most studies of audiovisual processing focus on neural mechanisms within healthy, young adults, we currently know very little about how changes to the brain can affect audiovisual integration in speech. To examine this further, …

Less Acting, More Doing: How Surface Acting Relates To Perceived Meeting Effectiveness And Other Employee Outcomes, Linda R. Shanock, Joseph A. Allen, Alexandra M. Dunn, Benjamin E. Baran, Cliff W. Scott, Steven G. Rogelberg

Psychology Faculty Publications

This study adds to the growing body of research on work meetings and extends the emotional labour literature beyond a service context by examining the relationship between surface acting during meetings and perceived meeting effectiveness. Additionally, the relationships of surface acting during meetings and perceived meeting effectiveness with time-lagged reports of intention to quit and emotional exhaustion 3 months later were investigated. Structural equation modelling of data from 178 working adults revealed negative relationships between surface acting and perceptions of meeting effectiveness. Perceived meeting effectiveness partially mediated the relationship between surface acting and both intention to quit and emotional exhaustion …

Regulation Of The Myostatin Protein In Overload-Induced Hypertrophied Rat Skeletal Muscle, Paige Abriel Affleck

Theses and Dissertations

Myostatin (GDF-8) is the chief chalone in skeletal muscle and negatively controls adult skeletal muscle growth. The role of myostatin during overload-induced hypertrophy of adult muscle is unclear. We tested the hypothesis that overloaded adult rodent skeletal muscle would result in reduced myostatin protein levels. Overload-induced hypertrophy was accomplished by unilateral tenotomy of the gastrocnemius tendon in male adult Sprague-Dawley rats followed by a two-week period of compensatory overload of the plantaris and soleus muscles. Western blot analysis was performed to evaluate changes in active, latent and precursor myostatin protein levels. Significant hypertrophy was noted in the plantaris (494 ± …

Shaping Swarms Through Coordinated Mediation, Shin-Young Jung

Theses and Dissertations

A swarm is a group of uninformed individuals that exhibit collective behaviors. Without any information about the external world, a swarm has limited ability to achieve complex goals. Prior work on human-swarm interaction methods allow a human to influence these uninformed individuals through either leadership or predation as informed agents that directly interact with humans. These methods of influence have two main limitations: (1) although leaders sustain influence over nominal agents for a long period of time, they tend to cause all collective structures to turn in to flocks (negating the benefit of other swarm formations) and (2) predators tend …

Abstract Models Of Molecular Walkers, Oleg Semenov

Computer Science ETDs

Recent advances in single-molecule chemistry have led to designs for artificial multi-pedal walkers that follow tracks of chemicals. The walkers, called molecular spiders, consist of a rigid chemically inert body and several flexible enzymatic legs. The legs can reversibly bind to chemical substrates on a surface, and through their enzymatic action convert them to products. We study abstract models of molecular spiders to evaluate how efficiently they can perform two tasks: molecular transport of cargo over tracks and search for targets on finite surfaces. For the single-spider model our simulations show a transient behavior wherein certain spiders move superdiffusively over …

Model Selection For Stochastic Block Models, Xiaoran Yan

Computer Science ETDs

As a flexible representation for complex systems, networks (graphs) model entities and their interactions as nodes and edges. In many real-world networks, nodes divide naturally into functional communities, where nodes in the same group connect to the rest of the network in similar ways. Discovering such communities is an important part of modeling networks, as community structure offers clues to the processes which generated the graph. The stochastic block model is a popular network model based on community structures. It splits nodes into blocks, within which all nodes are stochastically equivalent in terms of how they connect to the rest …

The Roles Of Phenotypic Plasticity And Genotypic Specialization In High Altitude Adaptation, Danielle M. Tufts

School of Biological Sciences: Dissertations, Theses, and Student Research

In vertebrates living at high altitude, arterial hypoxemia may be ameliorated by reversible changes in the oxygen-carrying capacity of the blood (regulated by erythropoiesis) and/or changes in blood–oxygen affinity (regulated by allosteric effectors of hemoglobin function). These hematological traits often differ between taxa that are native to different elevational zones, but it is often unknown whether the observed physiological differences reflect fixed, genetically based differences or environmentally induced acclimatization responses (phenotypic plasticity). Here, we report measurements of hematological traits related to blood–O₂ transport in populations of deer mice (Peromyscus maniculatus) that are native to high- and low-altitude …

Recent Developments In Slovak Competition Law - Legislation And Case Law Review, Zuzana Šabová, Katarína Fodorová, Daniela Lukáčová

Yearbook of Antitrust and Regulatory Studies

No abstract provided.

Evaluating Flexibility In International Patent Law, Sarah R. Wasserman Rajec

Faculty Publications

Global patent law has raced toward harmonization over the past decades. Countries with vastly different industries, values, and levels of development now offer robust patent rights with similar contours through membership in the World Trade Organization and consequent adoption of the Agreement on Trade-Related Aspects of Intellectual Property Rights (“TRIPS”). However, patent law is still far from harmonized among countries or static within countries. Jurisdictions tailor their patent laws to accommodate differences between industries, unforeseen inefficiencies, and diverse views of the costs and benefits associated with offering patent rights to stimulate innovation. Prior scholarly work consists of either doctrinal analyses …

Full Issue, Byu Studies

BYU Studies

No abstract provided.

The Viper On The Hearth, Updated Edition, Mickell J. Summerhays, Terryl L. Givens

BYU Studies

Terryl L. Givens, the well-known Mormon author, is a professor of literature and religion and is the James A. Bostwick Professor of English at the University of Richmond, Virginia. He has authored books such as By the Hand of Mormon: The American Scripture that Launched a New World Religion and The God Who Weeps: How Mormonism Makes Sense of Life.

Many may be familiar with Givens's classic study on Mormon literature entitled The Viper on the Hearth. It is known as one of the most in-depth studies of anti-Mormon literary texts. Givens himself calls this a look at "the long …

Relationships Among Walleye Mercury, Selenium, Stable Isotopes, Size And Age, Mark J. Fincel, Robert P. Hanten, Shannon Minerich

The Prairie Naturalist

Bioaccumulation of mercury is well-documented in aquatic ecosystems and occurs as mercury is accumulated and passed up food chains (Kidd et al. 1995, Atwell et al. 1998, Downs et al. 1998). Trophic level correlations have been widely reported for mercury (Snodgrass et al. 2000) and other metals (Barron 1995). Generally, within a system, carnivores have the highest mercury loadings, omnivores intermediate and herbivores the lowest (Phillips et al. 1980). However, little research has focused on the differences in mercury bioaccumulation for a single species that ranges across multiple trophic levels (Burger et al. 2001).

Stable isotope analysis has expanded the …

An Analysis Of A District-Led Leadership Seminar On The Dispositions Of Certified Staff Members, Michael J. Rupprecht

Student Work

The purpose of this study was to determine whether or not a district-led, grow-your-own leadership seminar had a significant impact on the dispositions of its members compared to staff members who did not participate in the program. The participants involved (N = 20) included a naturally formed group of certified staff members (n = 10) who attended and completed a nine-month, district-led, grow-your-own leadership seminar and a demographically-matched, randomly selected group of certified staff members (n = 10) who did not attend or complete the leadership seminar. The dependent variable used in this study was the Administrator Disposition Index (ADI), …

Private Enforcement Of Competition Law – The Case Of Estonia, Karin Sein

Yearbook of Antitrust and Regulatory Studies

Jurisprudence on private enforcement of competition law has so far been almost non-existent in Estonia. Most cases where competition law issues are raised within the context of damage claims are solved by out-of-court settlements. One of the main reasons for this scarcity is the fact that this is a fairly unfamiliar field for Estonian lawyers, attorneys and judges. The first reason for the low number of private enforcement of competition law cases in Estonia is therefore lacking awareness and legal uncertainty. The other key barrier lies in burden of proof issues associated with damage claims. It has proven very difficult …

Effects Of High Fidelity Simulation On Knowledge Acquisition, Self-Confidence, And Satisfaction With Baccalaureate Nursing Students Using The Solomon-Four Research Design, Rachel M. Hall

Electronic Theses and Dissertations

High Fidelity Simulation is a teaching strategy that is becoming well-entrenched in the world of nursing education and is rapidly expanding due to the challenges and demands of the health care environment. The problem addressed in this study is the conflicting research results regarding the effectiveness of HFS for students’ knowledge acquisition after participating in simulation exercises. Specifically this researcher determined the effects of a formatted simulation scenario on knowledge acquisition among nursing students and the students’ satisfaction and selfconfidence with the simulation learning activity. Kolb’s Experiential Learning Theory (1984) provided the framework for this study.

This study used a …

December 2013 Commencement Program, Bowling Green State University

Commencement Programs

No abstract provided.

Entering The 3rd Generation Of E-Learning: Characteristics And Strategies, Weiyuan Zhang

Journal of Educational Technology Development and Exchange (JETDE)

With the rapid development of e-Learning practices in education, the principles and methods of e-Learning have gradually evolved and matured. The purpose of this paper is to identify developmental stages of e-Learning and propose some strategies in establishing a new generation of e-Learning. First, the paper describes the three generations of e-Learning development. Second, the establishment of a 3rd generation e-Learning platform is analyzed. Third, course development in 3rd generation e-Learning is discussed. Using emerging new and user-friendly software, teachers and trainers could design and develop interactive e-Learning resources by themselves. Finally, the importance of staff development in e-Learning knowledge …

Introduction To The Economics Of Social Institutions, John B. Davis, Asimina Christoforou

Economics Faculty Research and Publications

This volume includes thirty-six important contributions to the economics of social institutions by leading figures in the history of the field. Its nine Parts are: Early Contributions, Methodological and Conceptual Issues, Old Institutionalism, New Institutionalism, Social Costs, Growth and Development, Institutions and Change, Institutions and Organizations, and The Third Sphere of the Economy and Institutions. This set of topics provides a comprehensive review of the origins and development of the economics of social institutions. It addresses the main theoretical and policy concerns that have occupied contributors to the approach. The economics of social institutions has a been well-established research program …

Native American Winters Doctrine And Stevens Treaty Water Rights: Recognition, Quantification, Management, Rachael Paschal Osborn

American Indian Law Journal

No abstract provided.

Political Cooperation And Procedural (In)Justice: A Study Of The Indian Reorganization Act, Sam Thypin-Bermeo

American Indian Law Journal

No abstract provided.

The Impact Of Companion Animals On Social Capital And Community Violence: Setting Research, Policy And Program Agendas, Phil Arkow

The Journal of Sociology & Social Welfare

The term social capital has been used to describe the networks and other forces that build social cohesion, personal investment, reciprocity, civic engagement, and interpersonal trust among residents in a community. With the exception of three Australian reports describing positive associations between companion animal ownership and social capital, the literature has neglected to include the presence or absence of companion animal residents of communities as factors that could potentially affect social capital and serve as protective factors for community well-being. Companion animals are present in significantly large numbers in most communities, where they have considerable economic impact and provide emotional …

"Leads" To Expanded Social Networks, Increased Civic Engagement And Divisions Within A Community: The Role Of Dogs, Catherine Simpson Bueker

The Journal of Sociology & Social Welfare

Dogs play a distinct role in their impact on human relationships and processes because of the unique role they play in American society, existing in a liminal space of "almost" human. Both the level of emotional attachment and the requisite daily care make dogs important players in bringing humans in contact with one another and mediating human relationships. This study examines the role that dogs play in mediating relationships between and among humans. By analyzing 24 in-depth interviews, as well as Letters to the Editor, editorials, and other items in a local newspaper, and observing public meetings around dog usage …

Shelter From The Storm: Companion Animal Emergency Planning In Nine States, Jessica J. Austin

The Journal of Sociology & Social Welfare

Failure to evacuate pets in an emergency has negative implications for public health, the economy, emotional well-being of pet owners, and physical health of animals. These effects may be at least partially mitigated by a robust plan to accommodate pets. Nine state companion animal emergency plans were reviewed to determine the extent to which they addressed the needs of companion animals, utilizing characteristics of a model emergency plan. States were compared utilizing variables such as population, pet friendliness, and emergency preparedness funding in order to explain differences in plan composition. This comprehensive review produced a list of recommendations for emergency …

Staff Views On The Involvement Of Animals In Care Home Life: An Exploratory Study, Jane Fossey, Vanessa Lawrence

The Journal of Sociology & Social Welfare

This qualitative study examined the views of one hundred and eight care staff working in fifteen care homes in the United Kingdom about the involvement Of animals in the care practices of the home. The perceived benefits and difficulties ofdelivering person-centered and psychosocial care, including the involvement of animals were explored. The findings describe the main themes related to animal involvement elicited from staff. These include the benefits to residents' well-being and the varying challenges that visiting and residential animals pose. The implicationsfor practice are discussed and the need for clearer information for care home teams is identified.

Graduate Student Attitudes Toward Different Instructional Approaches Within Face-To-Face, Online, And Blended Learning Environments In A Public Four-Year Institution Of Higher Learning, Philip Rotich

Electronic Theses and Dissertations

This study compared graduate student attitudes toward different instructional approaches within online, blended, and face-to-face courses in a public institution of higher learning. The participants completed an online survey questionnaire that was designed by the researcher using 4 learning theories in education: behavioral, cognitive, constructivism, and humanistic (Merriam, Caffarella, & Baumgartner, 2007) approaches toward teaching and learning. There were 210 total responses from graduate students enrolled during 2013 spring semester. There were more female (71.4%) than male (28.6%) students who responded. Previous studies have compared face-to-face (F2F) and online methods of instructions and have shown mixed results. Whereas some studies …