Digital Commons Network^™

Gene Expression Studies For The Analysis Of Domoic Acid Production In The Marine Diatom Pseudo-Nitzschia Multiseries, Katie Boissonneault, Brooks M. Henningsen, Stephen S. Bates, Deborah L. Robertson, Sean Milton, Jerry Pelletier, Deborah A. Hogan, David E. Housman

Dartmouth Scholarship

Pseudo-nitzschia multiseries Hasle (Hasle) (Ps-n) is distinctive among the ecologically important marine diatoms because it produces the neurotoxin domoic acid. Although the biology of Ps-n has been investigated intensely, the characterization of the genes and biochemical pathways leading to domoic acid biosynthesis has been limited. To identify transcripts whose levels correlate with domoic acid production, we analyzed Ps-n under conditions of high and low domoic acid production by cDNA microarray technology and reverse-transcription quantitative PCR (RT-qPCR) methods. Our goals included identifying and validating robust reference genes for Ps-n RNA expression analysis under these conditions.

Harnessing Poverty Alleviation To Reduce The Stigma Of Hiv In Sub-Saharan Africa, Alexander C. Tsai, David Bangsberg, Sheri D. Weiser

OHSU-PSU School of Public Health Faculty Publications and Presentations

HIV is highly stigmatized throughout sub-Saharan Africa. In studies conducted among general population samples, stigma has been shown to impede uptake of HIV testing and increase sexual risktaking behavior. Among HIV-infected persons, stigma has also been associated with inhibited serostatus disclosure to sexual partners and potential treatment supporters, delays in HIV antiretroviral therapy (ART) initiation, and ART nonadherence. The stigma of HIV also intensifies the poverty, stress, and insecurity endemic to many resource-limited settings, resulting in worsened mental health, itself an important determinant of AIDS-related mortality. Until we can better understand how to effectively intervene to reduce the stigma of …

Putting The Heart Back Into Writing: Nurturing Voice In Middle School Students, Barbara Ruben, Leanne Moll

Curriculum and Instruction Faculty Publications and Presentations

To gain a deeper understanding of young adolescent motivation and developmental needs as the nation plunges ahead with the national Common Core Standards and their implications for writing instruction, the authors of this article pondered five questions as they studied their own middle school writing team: (1) What intrinsic motivators drive these young students to write? (2) What components create a nurturing writing environment? (3) How can we understand student motivation so that we can nurture student interest in writing within the constraints of large classes and mandates to address Common Core Standards? (4) For students who are already intrinsically …

Understanding Causation In Private Securities Lawsuits: Building On Amgen, James D. Cox

Vanderbilt Law Review

The securities antifraud provision is a bastard. It has no indisputable parentage; its existence is attributed to a federal statute, but its features are borrowed from state law, a body of law that the enacting Congress presumably believed was inadequate.' Why would Congress borrow from state law that it considered deficient? Even though the antifraud provision has come of age largely through judicial construction similar to the laudatory process that underlies our common law, critics attack the antifraud provision like no comparable common-law development. To many scholars, private antifraud suits are not viewed as a net benefit, but as a …

Profiting From Regulation: Evidence From The European Carbon Market, James B. Bushnell, Howard Chong, Erin T. Mansur

Dartmouth Scholarship

We investigate how cap-and-trade regulation affects profits. In late April 2006, the EU CO2 allowance price dropped 50 percent, equating to a €28 billion reduction in the value of aggregate annual allowances. We examine daily returns for 552 stocks from the EUROSTOXX index. Despite reductions in environmental costs, we find that stock prices fell for firms in both carbon- and electricity-intensive industries, particularly for firms selling primarily within the EU. Our results imply that investors focus on product price impacts, rather than just compliance costs and the nominal value of pollution permits.

The Envenoming Pandemic And The Misguided Views Of Snakes: Developing Sustainable Relationships Between Native Poisonous Snakes Of India And The Citizens Of Maharashtra Through The Use Of The Irula Model., Destiny Villanueva

Animal Science

Due to its vast population and general negative consensus regarding snakes, India is notorious for having more snakebite incidents than any other country. Snakes are simultaneously revered and feared in Indian religion and culture. This stigma is perpetuated through propaganda, family beliefs, and innate fears of snakes.These stigmas are more pronounced within rural areas, such as the region of Mahad within the state of Maharshtra. Envenoming is endemic in these areas, and others like them. The World Health Organization identified envenoming as one of the most neglected tropical diseases of the 21st century (Nature India, 2013). Additionally, both nonvenomous and …

The Wooster Voice (Wooster, Oh), 2013-11-01, Wooster Voice Editors

The Voice: 2012-Present

The front page story "Campus Life works to fix broken housing selection process" assesses the student body's distrust with the housing lottery system. "Wooster ranks poorly in 'return on investment'" reports on an article by The Daily Beast that ranks Wooster eighth out of twenty on the worst returns on investment. The Features section looks at the rechartering of Kappa Epsilon Zeta (KEZ) along with an article on sexual content and alochol use. In Arts and Entertainment, there are articles on a screening of a documentary about Islamic Art and The Goliard, the literary magazine on campus, reviving the Covers …

Social Dynamics In Mixed-Income Developments, Mark L. Joseph, Taryn Gress

Faculty Scholarship

This report, the first “State of the Field Scan” from the newly launched National Initiative on Mixed-Income Communities at Case Western Reserve University (NIMC), is the first effort to conduct a data collection effort across a broad set of mixed-income developments nationwide. The goals of these State of the Field Scans are to: 1. generate a comparative description of the landscape of the mixed-income development field, 2. collect and analyze perceptions, experiences and insights from mixed-income practitioners on specific topics of pressing interest to the field, and 3. make contact and build relationships with a network of mixed-income developments and …

The Influence Of Mobile Website Quality On Consumer Satisfaction And Behavior, Xiuyuan Gao

Department of Textiles, Merchandising and Fashion Design: Dissertations, Theses, and Student Research

Mobile shopping has grown into a huge market and an increasing number of consumers have begun to use mobile websites to shop. Therefore, how mobile shopping websites provide good shopping to customers is significant. The object of this study is to relate factors of website quality to college students’ satisfaction with mobile shopping experiences, which in turn influence their intentions to return to the website and/or to purchase on the website. Five dimensions of website quality, which were information quality, navigation, visual appeal, response time and interactivity, were selected in this study. The model of self-regulatory process (Bagozzi, 1992) has …

Performative Memory: Form And Content In The Jewish Museum Berlin, Lisa A. Costello

Writing & Linguistics: Faculty Publications (1990-2022)

Work published in Liminalities: A Journal of Performance Studies.

Bilingual Language Switching And Selection At The Phonetic Level: Asymmetrical Transfer In Vot Production, Daniel J. Olson

School of Languages and Cultures Faculty Publications

The present study examines the effect of language switching on phonetic production, contributing to an understanding of the underlying interaction between a bilingual’s two phonetic systems. While phonetic interaction has been studied in non-switched and codeswitched paradigms, effects of connected speech (e.g. speech planning, pragmatics, etc.) may obscure underlying phonetic interaction. To investigate the impact of language switching, a cued picture-naming task was employed, with Spanish-English bilinguals of differing dominance profiles naming pictures in English and Spanish. Stimuli were produced both as switched and non-switched tokens. Addressing the impact of context, stimuli were presented in three contexts varying in quantity …

In My Humble But Correct Opinion-You Might Be A Zealot If…, Rick Anderson

Against the Grain

No abstract provided.

Lessons Learned: Jisc's Experience In Acquiring Multimedia Resources On Behalf Of Uk Academic Libraries, Lorraine Estelle

Against the Grain

No abstract provided.

Back Talk-The Ifla Trend Report, Anthony W. Ferguson

Against the Grain

No abstract provided.

At Brunning: People And Technology, Dennis Brunning

Against the Grain

No abstract provided.

Table Of Contents

Against the Grain

No abstract provided.

Shaping The Success Of Social Impact Bonds In The United States: Lessons Learned From The Privatization Of U.S. Prisons, Shifali Baliga

Duke Law Journal

American government officials are starting to experiment with a novel government-funding and privatization structure known as a social impact bond ("SIB"). An SIB is a contract between a government agency and a private entity in which the government agrees to pay the private entity an agreed-upon sum only if it can meet certain goals or outcomes. Currently, SIBs exist both globally and domestically, and are targeted to solve perpetual social ills such as the high homelessness and recidivism rates plaguing certain communities.

By analogizing the problems facing private prisons to the potential problems facing the use of SIBs, this Note …

Achieving World Trade Organization Compliance For Export Processing Zones While Maintaining Economic Competitiveness For Developing Countries , James J. Waters

Duke Law Journal

Export processing zones (EPZs) are statutorily created investment parks that developing countries establish to attract foreign investment in exchange for government-granted fiscal incentives. At their core, EPZs are a quid pro quo between host governments and investor companies: in exchange for the promise of job creation, technological transfer, economic development, and compliance with export performance requirements, investor companies receive substantial fiscal incentives, such as tax and tariff exemptions.

Most EPZ statutes are inconsistent with Article 3.1(a) of the World Trade Organization's Agreement on Subsidies and Countervailing Measures (SCM Agreement) because EPZ incentives qualify as prohibited export subsidies. Fortunately, many developing …

Predicting User's Political Party Using Ideological Stances, Swapna Gottopati, Minghui Qiu, Liu Yang, Feida Zhu, Jing Jiang

Research Collection School Of Computing and Information Systems

Predicting users political party in social media has important impacts on many real world applications such as targeted advertising, recommendation and personalization. Several political research studies on it indicate that political parties’ ideological beliefs on sociopolitical issues may influence the users political leaning. In our work, we exploit users’ ideological stances on controversial issues to predict political party of online users. We propose a collaborative filtering approach to solve the data sparsity problem of users stances on ideological topics and apply clustering method to group the users with the same party. We evaluated several state-of-the-art methods for party prediction task …

Observed Versus Gcm-Generated Local Tropical Cyclone Frequency: Comparisons Using A Spatial Lattice, Sarah Strazzo, Daniel J. Halperin, James Elsner, Tim Larow, Ming Zhao

Publications

Of broad scientific and public interest is the reliability of global climate models (GCMs) to simulate future regional and local tropical cyclone (TC) occurrences. Atmospheric GCMs are now able to generate vortices resembling actual TCs, but questions remain about their fidelity to observed TCs. Here the authors demonstrate a spatial lattice approach for comparing actual with simulated TC occurrences regionally using observed TCs from the International Best Track Archive for Climate Stewardship (IBTrACS) dataset and GCM-generated TCs from the Geophysical Fluid Dynamics Laboratory (GFDL) High Resolution Atmospheric Model (HiRAM) and Florida State University (FSU) Center for Ocean–Atmospheric Prediction Studies (COAPS) …

Ucc Minutes, November 19, 2013, University Curriculum Council

UCC Agendas/Minutes

No abstract provided.

Heterogeneity Of Functional Properties Of Clone 66 Murine Breast Cancer Cells Expressing Various Stem Cell Phenotypes, Partha Mukhopadhyay, Tracy Farrell, Gayatri Sharma, Timothy R. Mcguire, Barbara O'Kane, J. Graham Sharp

Journal Articles: Genetics, Cell Biology & Anatomy

INTRODUCTION:

Breast cancer grows, metastasizes and relapses from rare, therapy resistant cells with a stem cell phenotype (cancer stem cells/CSCs). However, there is a lack of studies comparing the functions of CSCs isolated using different phenotypes in order to determine if CSCs are homogeneous or heterogeneous.

METHODS:

Cells with various stem cell phenotypes were isolated by sorting from Clone 66 murine breast cancer cells that grow orthotopically in immune intact syngeneic mice. These populations were compared by in vitro functional assays for proliferation, growth, sphere and colony formation; and in vivo limiting dilution analysis of tumorigenesis.

RESULTS:

The proportion of …

Duty In The Litigation-Investment Agreement: The Choice Between Tort And Contract Norms When The Deal Breaks Down, Anthony J. Sebok, W. Bradley Wendel

Cornell Law Faculty Publications

Litigation investment, which is also known as “litigation finance” or “third party litigation finance,” has grown in importance in many common law and civilian legal systems and has come to the United States as well. While many questions remain about both legality and social desirability of litigation finance, this paper starts with the assumption that the practice will become widespread in the US and explores the obligations of the parties to the litigation finance contract.

The first part of the article uses an example to illustrate the risks imposed by one of the other party on the other which should …

Cyber-Republicanism, Sarah Tran

William & Mary Law Review

In 1787 at the dawn of our nation, the Founding Fathers were embroiled in a raging debate over the role citizens and special interest groups should play in our political system. The Founding Fathers viewed influence from interest groups as a threat to government decision making, but they differed in their responses to this perceived problem. Proponents of republicanism, one of the dominant conceptions of politics at that time, adopted an optimistic approach. They anticipated that government leaders and citizens, guided by their education and civic virtue, would not allow factional tyranny to flourish. This republican optimism continues to markedly …

Rethinking Review Standards In Asylum, Andrew Tae-Hyun Kim

William & Mary Law Review

Factual findings drive asylum adjudication. If immigration judges get them wrong, they risk sending refugees back to persecution. Recent studies have exposed an immigration agency that is prone to inaccurate and ill-considered fact-finding due to its structural problems. Without the political will or the financial capital necessary to fix what many acknowledge as a compromised system of adjudication, the agency may continue to render decisions that cast doubt on its capability and expertise. With an agency either unable or unwilling to ensure an accurate and fair fact-finding process, the first meaningful review of an asylum applicant’s claim happens at the …

Flunking The Class-Of-One/Failing Equal Protection, William D. Araiza

William & Mary Law Review

This Article considers the equal protection “class-of-one” doctrine in light of recent developments, both at the Supreme Court and in the lower courts. After Part I explains the background and current state of the doctrine, Part II considers how that doctrine provides insights into such basic equal protection concepts as discriminatory intent and animus. It also critiques the Court’s analysis of the class-of-one, arguing that the Court has mishandled these concepts and in so doing caused doctrinal anomalies and lower court confusion. Part II offers an alternative approach to the class-of-one that corrects those problems while still addressing the concerns …

Mental Health, Sleep Quality, Drinking Motives, And Alcohol-Related Consequences: A Path-Analytic Model, Shannon R. Kenney, Andrew Lac, Joseph W. Labrie, Justin F. Hummer, Andy Pham

Psychological Science Faculty Works

Objective: Poor mental health, sleep problems, drinking motivations, and high-risk drinking are prevalent among college students. However, research designed to explicate the interrelationships among these health risk behaviors is lacking. This study was designed to assess the direct and indirect influences of poor mental health (a latent factor consisting of depression, anxiety, and stress) to alcohol use and alcohol-related consequences through the mediators of global sleep quality and drinking motives in a comprehensive model.

Method: Participants were 1,044 heavy-drinking college students (66.3% female) who completed online surveys.

Results: A hybrid structural equation model tested hypotheses involving relations leading from poor …

Paleohydrology And The Origin Of Jewel Cave, National Cave And Karst Research Institute

KIP Articles

No abstract provided.

Sensing Charges Of The Ciona Intestinalis Voltage-Sensing Phosphatase, Carlos A. Villalba-Galea, Ludivine Frezza, Walter Sandtner, Francisco Bezanilla

School of Pharmacy Faculty Articles

Voltage control over enzymatic activity in voltage-sensitive phosphatases (VSPs) is conferred by a voltage-sensing domain (VSD) located in the N terminus. These VSDs are constituted by four putative transmembrane segments (S1 to S4) resembling those found in voltage-gated ion channels. The putative fourth segment (S4) of the VSD contains positive residues that likely function as voltage-sensing elements. To study in detail how these residues sense the plasma membrane potential, we have focused on five arginines in the S4 segment of the Ciona intestinalis VSP (Ci-VSP). After implementing a histidine scan, here we show that four arginine-to-histidine mutants, namely R223H to …

A Transformative Experience For Occupational Therapy Students In A Simulated Learning Environment, Kitsum Li, Barbara Mccamish

Collected Faculty Scholarship

Simulation is being integrated into nursing and medical curriculum nationally and it is well integrated into the Nursing program at Dominican University of California, However, use of simulation in allied health professionals is only an emerging practice. The aim of this program is to integrate simulation into the OT curriculum in order to facilitate the development of therapy foundation skill.