Digital Commons Network^™

John R. Visser: The Crossroads Of Poverty And Prosperity Study Guide, 2013, Steven Alan Samson

Faculty Publications and Presentations

No abstract provided.

Urban Watershed Services For Improved Ecosystem Management And Risk Reduction, Assessment Methods And Policy Instruments: State Of The Art, Yaella Depietri, Lorenzo Guadagno, Margaretha Breil

Fondazione Eni Enrico Mattei Working Papers

Under scenarios of increasing unplanned urban expansion, environmental degradation and hazard exposure, the vulnerability of urban populations, especially of their poorer segments, needs to be tackled through integrated economic, social and environmental solutions. Basing our analysis on the concept of ecosystem services, we suggest that urban areas would benefit from a shift in perspective towards a more regional approach, which recognizes them as one of many interconnected elements that interact at the watershed level. By integrating an ecosystem approach into the management of water-related services, urban management policies can take a first step towards fostering an improvement of the health …

Do Tregitopes Have The Potential To Impact The Current Treatment Landscape Of Autoimmune Diseases?, Anne S. De Groot

Institute for Immunology and Informatics Faculty Publications

Current treatment of autoimmune disease usually involves the use of cytotoxic drugs or biologic agents that interfere with the activity of B cells, T cells or key cytokines, such as TNF, IL-1 and IL-6. On occasion, polyclonal immunoglobulin G (IgG), intravenous (IVIg) is used. The discovery of IgG- (and hence IVIg-) derived T regulatory (Treg) epitopes that trigger the expansion of Tregs in vitro and in vivo provides a novel explanation for the effect of IVIg. These IgG-derived Treg epitopes (also known as Tregitopes) appear to be effective on their own (in vivo, in autoimmune disease models) and when co-administered …

Unilateral Reordering In The Reel World, Jake Linford

Scholarly Publications

No abstract provided.

Gallium Nitrate Is Efficacious In Murine Models Of Tuberculosis And Inhibits Key Bacterial Fe-Dependent Enzymes, Oyebode Olakanmi, Banurekha Kesavalu, Rajamouli Pasula, Maher Y. Abdalla, Larry S. Schlesinger, Bradley E. Britigan

United States Department of Veterans Affairs: Publications

Acquiring iron (Fe) is critical to the metabolism and growth of Mycobacterium tuberculosis. Disruption of Fe metabolism is a potential approach for novel antituberculous therapy. Gallium (Ga) has many similarities to Fe. Biological systems are often unable to distinguish Ga³⁺ from Fe³⁺. Unlike Fe³⁺, Ga³⁺ cannot be physiologically reduced to Ga²⁺. Thus, substituting Ga for Fe in the active site of enzymes may render them nonfunctional. We previously showed that Ga inhibits growth of M. tuberculosis in broth and within cultured human macrophages. We now report that Ga(NO₃)_{3 …}

First State Record And Interdiction For The Wood Slave, Hemidactylus Mabouia (Moreau De Jonnès 1818) (Gekkonidae), In Maryland, Usa., Louis A. Somma, William L. Grogan Jr.

Papers in Herpetology

The Wood Slave, Hemidactylus mabouia (Moreau de Jonnès 1818; Fig. 1), is indigenous to Africa south of the Sahara, with nonindigenous populations established in Cape Verde, Mexico, much of Central and South America, numerous localities in the Caribbean, perhaps Madagascar, and at least 21 counties in Florida, USA (Carranza and Arnold 2006; Kraus 2009; Krysko et al. 2011a, 2011b; Meshaka 2011; Powell and Henderson 2012). Recently, H. mabouia has successfully invaded temperate regions of southern Africa and northern peninsular Florida (Alexander and Marais 2007, Krysko and Somma 2007).

On 20 December 2012, Brian R. Grogan and Shane Forsythe collected and …

Repeated Asenapine Treatment Produces A Sensitization Effect In Two Preclinical Tests Of Antipsychotic Activity, Rongyin Qin, Yingzhu Chen, Ming Li

Department of Psychology: Faculty Publications

Among several commonly used atypical antipsychotic drugs, olanzapine and risperidone cause a sensitization effect in the conditioned avoidance response (CAR) and phencyclidine (PCP)- induced hyperlocomotion paradigms – two well established animal tests of antipsychotic drugs, whereas clozapine causes a tolerance effect. Asenapine is a novel antipsychotic drug recently approved for the treatment of schizophrenia and manic disorders. It shares several receptor binding sites and behavioral features with other atypical antipsychotic drugs. However, it is not clear what type of repeated effect (sensitization or tolerance) asenapine would induce, and whether such an effect is transferrable to other atypicals. In this study, …

Jewish Genetic Origins In The Context Of Past Historical And Anthropological Inquiries, John M. Efron

Human Biology Open Access Pre-Prints

The contemporary study of Jewish genetics has a long prehistory dating back to the eighteenth century. Prior to the era of genetics studies of the physical makeup of Jews were undertaken by comparative anatomists and physical anthropologists. In the nineteenth century the field was referred to as “race science.” Believed by many race scientists to be a homogeneous and pure race, Jews occupied a central position in the discourse of race science because they were seen as the control group par excellence to determine the relative primacy of nature or nurture in the development of racial characteristics. In the nineteenth …

Faculty Senate Meeting Minutes – December 2013, Faculty Senators

Minutes 2013-2014

This is the archived record of the December 11, 2013 faculty senate meeting minutes.

Chromatin-Induced Spindle Assembly Plays An Important Role In Metaphase Congression Of Silkworm Holocentric Chromosomes, Hiroaki Mon, Jae Man Lee, Kazuei Mita, Marian R. Goldsmith, Takahiro Kusakabe

Biological Sciences Faculty Publications

The kinetochore plays important roles in cell cycle progression. Interactions between 4 chromosomes and spindle microtubules allow chromosomes to congress to the middle of the 5 cell and to segregate the sister chromatids into daughter cells in mitosis. The chromosome 6 passenger complex (CPC), composed of the Aurora B kinase and its regulatory subunits 7 INCENP, Survivin, and Borealin, plays multiple roles in these chromosomal events. In the 8 genome of the silkworm, Bombyx mori, which has holocentric chromosomes, the CPC 9 components and their molecular interactions were highly conserved. In contrast to 10 monocentric species, however, the silkworm CPC …

Infrared Skin Damage Thresholds From 1319-Nm Continous-Wave Laser Exposures, Jeffrey W. Oliver, Revecca Vincelette, Gary Noojin, Clifton D. Clark, Corey Harbert, Kurt J. Schuster, Aurora D. Schingledecker, Semih S. Kumru, Justin Maughan, Naomi Kitzis, Gavin D. Buffington, David J. Stolarski, Robert J. Thomas

Physics Faculty Publications

A series of experiments were conducted in vivo using Yucatan miniature pigs (Sus scrofa domestica) to determine thermal damage thresholds to the skin from 1319-nm continuous-wave Nd:YAG laser irradiation. Experiments employed exposure durations of 0.25, 1.0, 2.5, and 10 s and beam diameters of ∼0.6 and 1 cm. Thermal imagery data provided a time-dependent surface temperature response from the laser. A damage endpoint of fifty percent probability of a minimally visible effect was used to determine threshold for damage at 1 and 24 h postexposure. Predicted thermal response and damage thresholds are compared with a numerical model of opticalthermal interaction. …

Annual Report Of Research And Creative Productions By Faculty And Staff, January To December, 2013, Research And Creative Productions Committee. Morehead State University.

Office of Research and Sponsored Programs Reports and Publications

Annual Report Of Research and Creative Productions by Faculty and Staff from January to December, 2013.

Gonadal Status-Dependent Effects Of In Vivo Β-Estradiol Administration To Female Rats On In Vitro Epileptiform Activity Induced By Low [Mg2+]₀ In Combined Hippocampus-Entorhinal Cortex Slices, Jana Velíšková, Libor Velíšek

NYMC Faculty Publications

There are controversial data regarding estrogen effects on neuronal excitability. We investigated whether β-estradiol (EB) administration to ovariectomized (OVX) or gonadally intact female rats alters epileptiform activity within the dentate gyrus network induced in vitro by removing [Mg2+]o in combined hippocampus-entorhinal cortex slices. In vivo EB administration significantly influenced the epileptiform activity in gonadal status-dependent manner. The onset of epileptiform discharges was modestly delayed in slices from OVX rats replaced with physiologically relevant doses of EB but the number of discharges was not affected. In contrast, EB administration to gonadally intact rats had robust effects such that: EB delayed the …

Northwest Arkansas Consumer Perceptions Of Poultry Production, Stuart Estes

Agricultural Education, Communications and Technology Undergraduate Honors Theses

Poultry production holds an important place in Arkansas economically and as a food source. The importance of poultry production ultimately hinges on the demands of the consumers and the perceptions that drive their purchases. With this in mind, this study surveyed consumers to assess their perceptions of poultry production in Arkansas. The instrument used to survey consumers was created by the researcher and an expert committee at the University of Arkansas. Consumers were interviewed through direct communication at grocery stores in northwest Arkansas. Data gathered from the study were analyzed for descriptive and correlational statistics. Data showed that consumers were …

Omj Is 10th Of 84 Journals In Quality Of Business Education Articles, William P. Ferris

Organization Management Journal

No abstract provided.

Machines In Desolation: Images Of Technology In The Great Basin Of The American West, Todd Shallat

History Faculty Publications and Presentations

Mythic thinking about technology as an engine of progress has shaped the ways Americans have come to perceive the boundaries of vacant space. In the Great Basin of the Rocky Mountains, where the West still appears to the East as empty and formless, photography and art tell richly symbolic stories about wastelands transformed into wealth. Often those stories aggrandize machines and engineering. The essay presents a visual sampling of machines remaking the desert from three historical eras. First, from the postbellum era of the transcontinental railroad, are pictures of barrens redeemed by science and industrialization. Second, from pioneer Utah, are …

Early Chronic Low-Level Lead Exposure Produces Glomerular Hypertrophy In Young C57bl/6j Mice, Christina Sobin, John Basgen

Selected Works Temporary Series

Early chronic lead exposure continues to pose serious health risks for children, particularly those living in lower socioeconomic environments. This study examined effects on developing glomeruli in young C57BL/6J mice exposed to low (30 ppm), higher (330 ppm) or no lead via dams’ drinking water from birth to sacrifice on post-natal day 28. Low-level lead exposed mice [BLL mean (SD); 3.19 (0.70) µg/dL] had an increase in glomerular volume but no change in podocyte number compared to control mice [0.03 (0.01) µg/dL]. Higher-level lead exposed mice [14.68 (2.74) µg/dL] had no change in either glomerular volume or podocyte number. The …

Iptakalim Attenuates Self-Administration And Acquired Goal-Tracking Behavior Controlled By Nicotine, S. Charntikov, N. Swalve, Steven T. Pittenger, K. Fink, S. Schepers, G. C. Hadlock, A. E. Fleckenstein, G. Hu, Ming Li, Rick A. Bevins

Department of Psychology: Faculty Publications

Iptakalim is an ATP-sensitive potassium channel opener, as well as an a4b2-containing nicotinic acetylcholine receptor (nAChR) antagonist. Pretreatment with iptakalim diminishes nicotine-induced dopamine (DA) and glutamate release in the nucleus accumbens. This neuropharmacological profile suggests that iptakalim may be useful for treatment of nicotine dependence. Thus, we examined the effects of iptakalim in two preclinical models. First, the impact of iptakalim on the interoceptive stimulus effect of nicotine was evaluated by training rats in a discriminated goal-tracking task that included intermixed nicotine (0.4 mg/kg, SC) and saline sessions. Sucrose was intermittently presented in a responseindependent manner only on nicotine sessions. …

Global Digital Elevation Model Accuracy Assessment In The Himalaya, Nepal, Luke G. Miles

Masters Theses & Specialist Projects

Digital Elevation Models (DEMs) are digital representations of surface topography or terrain. Collection of DEM data can be done directly through surveying and taking ground control point (GCP) data in the field or indirectly with remote sensing using a variety of techniques. The accuracies of DEM data can be problematic, especially in rugged terrain or when differing data acquisition techniques are combined. For the present study, ground data were taken in various protected areas in the mountainous regions of Nepal. Elevation, slope, and aspect were measured at nearly 2000 locations. These ground data were imported into a Geographic Information System …

A Preliminary Study For Estimating Postmortem Interval Of Fabric Degradation In Central Florida, Lorraine L. Humbert

HIM 1990-2015

Forensic anthropologists rely on forensic evidence to estimate the postmortem interval of a decedent. This may include the study of the degree of deterioration of the human body, the life stage of insects, and the degradation of associated material evidence. Material evidence comes in many forms, and certain taphonomic processes will affect the material and must be considered when making inferences about a PMI. These include variables such as the characteristics of the soil, microorganisms, and the presence of a decaying organic material. Previous research has undertaken studies in how fabric degrades over time; however, there is no standard methodology …

L’Empreinte Du Renard De Moussa Konaté Et Les Transformations Africaines Du Polar, Alexie Tcheuyap

Présence Francophone: Revue internationale de langue et de littérature

Within sub-Saharan Africa, Moussa Konaté is undoubtedly the contemporary writer dedicated to producing the most original crime fiction. In L’empreinte du renard, he offers a fundamental subversion of the genre that breaks with conventional thought on crime narratives. Moreover, the subversion of the canon accompanies a subversion of political structures by which the end of the story accompanies the end of the postcolonial state as it is known, and often caricatured: the State of corruption. As a result, such intrigue also becomes that of governmentability.

December 2013: Volume 3 Issue 1, Dacus Library

Dacus Developments

In this Issue:

That Sheep May Safely Graze ...
Dacus Library of Winthrop University
Friends of Dacus Library Endowment Fund Grows...

Cinema In The Digital Age: A Rebuttal To Lev Manovich, Barbara Cail

Philosophy

In his book The Language of New Media, Lev Manovich claims the index is an ontological condition of cinema. Manovich asserts digital cinema can never be indexical and therefore has fundamentally altered the very nature of cinema, reducing it to a form of animation. This paper offers a refutation of Manovich’s redefinition of cinema, showing that digital cinema can be indexical, but indexicality is not an ontological condition of cinema.

Representation And Appropriation In Guamán Poma De Ayala, Julio Ortega, Philip Debenshire

Journal of Global Initiatives: Policy, Pedagogy, Perspective

By discussing the cultural role of iconography, this article explores the likely source of representations in Felipe Guaman Pomade Ayala's The First New Chronicle and Good Government. His process of appropriation serves as a model of the new Andean cultural production by showcasing how emblematic allegories have been used in Latin America to illustrate Colonial manuscripts as well as national emblems and public art.

La Lidia Del Toro Bravo: Una Aproximación A La Controversia, Juan De Mesa

The Kennesaw Tower Undergraduate Foreign Language Research Journal

Bullfighting is a complex and highly controversial subject that continues to generate passionate discussions in contemporary Spanish society. This essay examines bullfights and bullfighting by examining several arguments and viewpoints related to this tradition. To provide the reader with a global perspective, attention is also given to various historical, cultural, and social elements surrounding bullfighting.

Differential Habitat Use By Common Watersnakes (Nerodia Sipedon), Lorin A. Neuman-Lee, Andrew M. Durso, Nicholas M. Kiriazis, Melanie J. Olds, Stephen J. Mullin

Faculty Research & Creative Activity

Understanding intraspecific variation in habitat use is important for the management of any species. In many studies of reptiles, habitat use by juveniles is poorly understood when compared to their adult conspecifics because of capture biases and logistical constraints. We compared habitat use between sexes and age classes of Common Watersnakes (Nerodia sipedon) at a reservoir in central Illinois. Juvenile N. sipedon occurred more frequently in habitat with high canopy cover, whereas adult N. sipedon, especially reproductive females, were found exclusively in habitat with no canopy cover. Adult males used both locations equally. We emphasize the need to investigate ontogenetic …

Photo-Identification Methods Reveal Seasonal And Long-Term Site-Fidelity Of Risso’S Dolphins (Grampus Griseus) In Shallow Waters (Cardigan Bay, Wales), Marijke N. De Boer, Josephine Clark, Mardik F. Leopold, Mark P. Simmonds, Peter J.H. Reijnders

Ecology Collection

A photo-identification study on Risso’s dolphins was carried out off Bardsey Island in Wales (July to September, 1997-2007). Their local abundance was estimated using two different analytical techniques: 1) mark-recapture of well-marked dolphins using a “closed-population” model; and 2) a census technique based on the total number of iden-tified individual dolphins sighted over the study period. The mark-recapture estimates of 121 (left sides; 64 - 178, 95% CI; CV 0.24) and 145 dolphins (right sides; 78 - 213, 95% CI; CV 0.24) closely matched the census technique estimates (population size of 90 - 151). It was found that the dolphins …

Practical Handling Skills During Road Transport Of Fattening Pigs From Farm To Slaughterhouse: A Brief Review, Bert Driessen, Ester Peeters, Jos Van Thielen, Sanne Van Beirendonck

Transport of Farm Animals Collection

The transport of fattening pigs is characterized by a strong human-animal interaction. Consequent handling is important because of animal welfare, meat quality and matching economic consequences. During road transport, human impact can be divided in different steps: 1) driving pigs from the pens via an alley to the trailer, 2) loading, 3) actual transport, 4) unloading to the lairage, and 5) the final phase driving pigs to the stunning. An inadequate design and a poor condition of the facilities will negatively affect the ease of handling pigs. Because of the consequences, acute stress during transport and slaughter should be minimized …

The Welfare Of Animals In The Chicken Industry

Agribusiness Reports

More than 8.5 billion chickens are slaughtered for meat production in the United States every year. Raised in industrial production systems, these animals experience crowded indoor confinement, unnatural lighting regimes, poor air quality, stressful handling and transportation, and inadequate stunning and slaughter procedures. Because they are selectively bred for rapid growth, broiler chickens are prone to a variety of severe skeletal and metabolic disorders that can cause suffering, pain, and even death. Broiler breeders, the parent birds of chickens raised for meat, are subjected to severe feed restriction, and males may undergo painful toe and beak amputations, performed without pain …

Longevity And Mortality Of Owned Dogs In England, D. G. O'Neill, D. B. Church, P. D. Mcgreevy, P. C. Thomson, D. C. Brodbelt

Epidemiology Collection

Improved understanding of longevity represents a significant welfare opportunity for the domestic dog, given its unparalleled morphological diversity. Epidemiological research using electronic patient records (EPRs) collected from primary veterinary practices overcomes many inherent limitations of referral clinic, owner questionnaire and pet insurance data. Clinical health data from 102,609 owned dogs attending first opinion veterinary practices (n = 86) in central and southeast England were analysed, focusing on 5095 confirmed deaths.

Of deceased dogs with information available, 3961 (77.9%) were purebred, 2386 (47.0%) were female, 2528 (49.8%) were neutered and 1105 (21.7%) were insured. The overall median longevity was 12.0 years …