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Early Embryonic Development, Assisted Reproductive Technologies, And Pluripotent Stem Cell Biology In Domestic Mammals, V. Hall, K. Hinrichs, G. Lazzari, D. H. Betts, P. Hyttel

Paediatrics Publications

Over many decades assisted reproductive technologies, including artificial insemination, embryo transfer, in vitro production (IVP) of embryos, cloning by somatic cell nuclear transfer (SCNT), and stem cell culture, have been developed with the aim of refining breeding strategies for improved production and health in animal husbandry. More recently, biomedical applications of these technologies, in particular, SCNT and stem cell culture, have been pursued in domestic mammals in order to create models for human disease and therapy. The following review focuses on presenting important aspects of pre-implantation development in cattle, pigs, horses, and dogs. Biological aspects and impact of assisted reproductive …

Cold Tolerance Of The Eastern Subterranean Termite, Reticulitermes Flavipes (Isoptera: Rhinotermitidae), In Ontario., Matthew W. Clarke, Graham J. Thompson, Brent J Sinclair

Biology Publications

We characterized the cold tolerance of natural populations of the Eastern subterranean termite (Reticulitermes flavipes (Kollar) [Isoptera, Rhinotermitidae]) in southwestern Ontario, Canada. We measured cold tolerance in workers from six colonies of termites established from Pelee Island in Lake Erie, and Point Pelee National Park. The mean critical thermal minimum, at which termites entered chill coma, ranged from 8.1 to 5.7°C. Mean supercooling points (SCP, the temperature at which individuals freeze) ranged from -4 to -4.6°C, and did not differ significantly between colonies, nor was SCP dependent on body size. Individuals survived brief exposure to low temperatures, as long as …

Social Presence And Therapeutic Demands: The Role Of Technology In The Therapeutic Alliance, Amy Lopez

Electronic Theses and Dissertations

This research explores whether access to technology mediated resources that expand social presence opportunities during mental health treatment play a role in what therapists report as difficult therapeutic alliance demands. Borderline Personality Disorder (BPD) is a serious mental health problem, characterized by unstable relationships, anger outbursts and impulsive behaviors. People with BPD tend to be high service users and have difficulty remaining in the treatment setting long enough to benefit from treatment services. Treatment studies have found that the therapeutic alliance is a significant contributing factor to successful outcomes; however, the relational and behavioral difficulties inherent among those diagnosed with …

Lindenwood University Student Handbook, 2013-2014, Lindenwood University

Student Handbooks

Information and guidelines for Lindenwood University students.

Patronage Politics And Natural Resources: A Historical Case Study Of Malaysia And Singapore, H. Varkkey

Research Publications (2011 to 2015)

As the modernisation of agribusiness became a more important driver of development for many Southeast Asian states, the region’s environment has become severely degraded. This paper argues that throughout the developmental history of Southeast Asia, the role of patronage politics has been a key factor behind environmental degradation. This paper focuses on Malaysia and Singapore as select case studies to show how political realities encourage patronage politics in the pursuit of development. It presents historical evidence concerning the circumstances preceding and surrounding early appearances of patronage networks in these countries, particularly within the natural resource sector. It argues that upon …

“Sucking On [America’S] Tit”: Metaphorical Dimensions Of The Family In Conservative American Discourses On Europe, G.H. Joost Baarsen

Traversea: The Journal of Transatlantic History

I will be keen to track how “adulthood,” “maturity,” “dependence” and “independence,” and the feminine/masculine function, and how these inform political discussions in the United States. I contend that the metaphor of parent and child is used with such fervor precisely because this one simple image clearly visualizes a panoply of narratives conservatives hold about Europe. The image invokes questions of authority and authorship — who gets to “author” the idea that Europe is a child in the first place? – and makes Europe exist as these Americans “know” it.7 This renders America’s superiority both explicit and implicit. Although I …

Moving Domain Computational Fluid Dynamics To Interface With An Embryonic Model Of Cardiac Morphogenesis, Juhyun Lee, Mahdi Esmaily Moghadam, Ethan Kung, Hung Cao, Tyler Beebe, Yury Miller, Beth L. Roman, Ching-Ling Lien, Neil C. Chi, Alison L. Marsden, Tzung K. Hsiai

Publications

Peristaltic contraction of the embryonic heart tube produces time- and spatial-varying wall shear stress (WSS) and pressure gradients (∇P) across the atrioventricular (AV) canal. Zebrafish (Danio rerio) are a genetically tractable system to investigate cardiac morphogenesis. The use of Tg(fli1a:EGFP)y1 transgenic embryos allowed for delineation and two-dimensional reconstruction of the endocardium. This time-varying wall motion was then prescribed in a two-dimensional moving domain computational fluid dynamics (CFD) model, providing new insights into spatial and temporal variations in WSS and ∇P during cardiac development. The CFD simulations were validated with particle image …

Metastatic Castration-Resistant Prostate Cancer: Critical Review Of Enzalutamide, Joelle El-Amm, Nihar Patel, Ashley Freeman, Jeanny B. Aragon-Ching

Medicine Faculty Publications

Enzalutamide, previously known as MDV300, is an oral, second-generation androgen receptor (AR) signaling inhibitor or antagonist that was approved by the Food and Drug Administration in 2012 for the treatment of metastatic castrate-resistant prostate cancer (mCRPC) postdocetaxel. Preclinical studies have demonstrated impressive affinity to the AR compared to the first-generation AR inhibitors. The landmark Phase III AFFIRM trial demonstrated improved overall survival benefit compared to placebo in addition to improvement in all tested parameters. Enzalutamide is currently being studied in several trials prechemotherapy and in earlier settings of prostate cancer. This review will discuss the mechanism of action of enzalutamide, …

An Exploration Of Heat Tolerance In Mice Utilizing Mrna And Microrna Expression Analysis, Islam Aminul, Patricia A. Deuster, Joseph M. Devaney, Svetlana Ghimbovschi, Yifan Chen

Genomics and Precision Medicine Faculty Publications

Background

Individuals who rapidly develop hyperthermia during heat exposure (heat-intolerant) are vulnerable to heat associated illness and injury. We recently reported that heat intolerant mice exhibit complex alterations in stress proteins in response to heat exposure. In the present study, we further explored the role of genes and molecular networks associated with heat tolerance in mice.

Methodology

Heat-induced physiological and biochemical changes were assessed to determine heat tolerance levels in mice. We performed RNA and microRNA expression profiling on mouse gastrocnemius muscle tissue samples to determine novel biological pathways associated with heat tolerance.

Principal Findings

Mice (n = 18) were …

Enhanced Nicotine Self-Administration And Suppressed Dopaminergic Systems In A Rat Model Of Diabetes, Laura O'Dell

Departmental Papers (Psych)

Patients with diabetes display a heightened propensity to use tobacco; however, it is unclear whether they experience enhanced rewarding effects of nicotine. Thus, this study examined the reinforcing effects of nicotine in a rodent model of diabetes involving administration of streptozotocin (STZ), a drug that is toxic to pancreatic insulin-producing cells. The first study compared STZ- and vehicle-treated rats that had 23-hour access to intravenous self-administration (IVSA) of nicotine or saline and concomitant access to food and water. In order to examine the contribution of dopamine to our behavioral effects, dopamine transporter (DAT), D1 and D2 receptor levels were compared …

Female Rats Display Enhanced Rewarding Effects Of Ethanol That Are Hormone Dependent, Laura O'Dell

Departmental Papers (Psych)

Background: Ethanol (EtOH) abuse is a major health and economic concern, particularly for females who appear to be more sensitive to the rewarding effects of EtOH. This study compared sex differences to the rewarding and aversive effects of EtOH using place-conditioning procedures in rats. Methods: Separate groups of adult (male, female, ovariectomized [OVX] female) and adolescent (male and female) rats received EtOH (0, 0.5, 1.0, 2.0 or 2.5 g/kg; i.p.) and were confined to their initially nonpreferred side of our conditioning apparatus for 30 minutes. On alternate days, they received saline and were confined to the other side. Following 5 …

The Effects Of Animal Assisted Therapy On Students, Cass Beasley

Education Masters

This study examined the benefits of using animal assisted therapy student behavior/concentration to read and their motivation to read. Research was conducted in the students’ homes with the use of a certified therapy dog during reading and writing activities. Data was collected through observations, student and parent questionnaires, and examination and analysis of student work samples. The findings show that the presence of a therapy dog can improve student behavior/concentration to read and write as well as motivation to read and write. Therapy dogs should be used in addition to everyday instruction as a behavioral management tool and motivator for …

Animal Waste Management Practices In The Monteverde Zone: Perceptions, Barriers, And Solutions, August 2013, Jordan Atnip, Jillian Flavin, Joseph Friedman, Elana Curry, Radhe Patel, Thomas Decker

Monteverde Institute: Culture, Community, and Health

Using methodologies from medical anthropology and environmental engineering animal waste treatment practices in Monteverde were investigated to assess current practices, future intentions, and how perceptions of farm impacts are changing in the region, and identify potential practices and technologies that could facilitate changes.

Oria Stage Ii Expansion: Keep River Baseline Aquatic Fauna And Targeted Sawfish Surveys - September/October 2012, Wetland Research And Management (Wrm), Landcorp

Irrigated Agricultural Development in the North

The Western Australian Government is developing additional land for irrigated agriculture adjacent to the existing Ord River Irrigation Area (Ord Stage 1), in the Kimberley region of Western Australia. The expansion, referred to as greater Ord Stage 2 has identified land along the lower Ord (Packsaddle, West Bank, Carlton Station and Mantinea), the Cockatoo Sands, as well as the Weaber, Keep River and Knox Creek Plains as suitable for development. The current development of the Weaber and Knox Creek Plains, referred to as the M2 Supply Area, will increase the current area under irrigation from 14,000 to potentially 30, 500 …

Mock Trials And Real Justices And Judges, Richard A. Posner

Articles

No abstract provided.

Local Recruitment And Natal Dispersal Distances Of American Kestrels, Karen Steenhof, Julie A. Heath

Biology Faculty Publications and Presentations

Variation in recruitment patterns and dispersal behavior can have important consequences for population viability, genetic structure, and rates of evolutionary change. From 1992 to 2006 we studied a marked population of American Kestrels (Falco sparverius) nesting in boxes in southwestern Idaho to identify factors that affect local recruitment and natal dispersal distances. A low proportion (4%) of locally produced kestrels (n = 2180) returned to nest in study area boxes. Offspring of locally produced individuals were 3.1 times more likely to return than offspring of parents that did not hatch in study area boxes and, independent of …

Augh2013, Robert Kelly

Robert Kelly Manuscripts

From August 2013 Robert Kelly Archives

2013 Applied Projects Evaluation Organizational Impact Report, Svetlana Krasynska, Jennifer A. Jones, Mary Jo Schumann

USD Evaluation of Applied Learning Model in Nonprofit Leadership and Management Master's Program

University of San Diego’s Nonprofit Leadership and Management (NLM) master’s degree program places a special focus on experiential learning, requiring students to complete multiple applied projects as part of the program’s curriculum. Applied projects give students various opportunities to work in teams to provide real-world consulting services to nonprofit and philanthropic organizations. In developing this curriculum, the NLM program serves both the students who are given these real-world consulting opportunities, as well as the client organizations who benefit from the services provided by the students.

In Fall 2010, the University of San Diego’s NLM program initiated an Applied Projects Evaluation …

August 2013 News Releases, University Of Montana--Missoula. Office Of University Relations

University of Montana News Releases, 1928, 1956-present

No abstract provided.

Speleo Spiel, No. 397, July-August 2013, Matt Cracknell

Speleo Spiel

Contents: Regular Bits -- Trip Reports -- Other Exciting Stuff

Measurement Of Emissions From A Passenger Truck Fueled With Biodiesel From Different Feedstocks, Natchanok Pala-En, Melanie L. Sattler, Brian Dennis, Victoria Chen, Rachel L. Muncrief

Civil Engineering Faculty Publications - Archive

Biodiesel has generated increased interest recently as an alternative to petroleum-derived diesel. Due to its high oxygen content, biodiesel typically burns more completely than petroleum diesel, and thus has lower emissions of hydrocarbons (HC), carbon monoxide (CO), and particulate matter (PM). However, biodiesel may increase or decrease nitrogen oxide (NOx) and carbon dioxide (CO2) emissions, depending on biodiesel feedstock, engine type, and test cycle. The purpose of this study was to compare emissions from 20% blends of biodiesel made from 4 feedstocks (soybean oil, canola oil, waste cooking oil, and animal fat) with emissions from ultra low sulfur diesel (ULSD). …

China And The Northeast Region: Agricultural Machinery, Kelsey White

Undergraduate Honors Capstone Projects

Using Chinese government statistical data, relevant laws and policy regulations, and current market projections, this report aims to help new-to-market U.S. exporters understand the development of the agricultural machinery market in China and the Northeast region, identifying both challenges and opportunities.

With a vast land area and diverse topography, China is one of the world's top agricultural producers. Agriculture accounts for about 11% of China's GDP and more than 40% of China's employment. Over the past several years, China has been increasing its agricultural mechanization in an effort to move from traditional to modern farming. The central government has been …

A Rhetorical Analysis Of Strategic Communication In The Amalga Barrens Wetlands Controversy, Laura Vernon

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Laura Vernon conducts a study to discover how, against the odds, the Bridgerland Audubon Society (BAS), located in Cache Valley, Utah, influenced a change in public policy regarding the Amalga Barrens reservoir proposal. In 1991, the state of Utah proposed developing the Bear River in northern Utah and constructing an off-stream storage facility (a reservoir) on the wetlands known as the Barrens near the town of Amalga. The Barrens served as a bird habitat for migrating shorebirds and waterfowl. In the late 1990s, BAS led a grassroots effort to remove the Barrens as a proposed site from the Bear River …

Jack London: Landscape, Love, And Place, Kristin Yoshiko Ladd

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

In Jack London: Landscape, Love, and Place, American Studies theories and methods formed the prime basis for analysis of London's biography, historical context, and literary significance. Particularly, the ideas of agrarianism, the Turner Thesis moment, Western literature, American masculinity, Victorian ideals, and sustainable farm practices in America were used to understand London's motivations for writing and creating his farm, his influence on American literature, and his texts' abilities to open avenues between literature and place-based education. Key concepts that influenced how London's works could be incorporated into and applied to didactic theory included David Sobel's seminal works in place-based education. …

Climate Change And Plant Demography In The Sagebrush Steppe, Aldo Compagnoni

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

We used demographic methods to address one of the main challenges facing ecological science: forecasting the effect of climate change on plant communities. Ecological forecasts will be crucial to inform long-term planning in wildland management and demographic methods are ideal to quantify changes in plant abundance. We carried out our research in the sagebrush steppe, one of the most extensive plant ecosystems of Western North America. Our research intended to inform ecological forecasts on an exotic invader, cheatgrass (Bromus tectorum). Moreover, we investigated the general question asking: to what degree competition among plants influences the outcome of ecological …

Selected Neuropharmacology Of Resurgence, Adam D. Pyszczynski

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The reemergence of problem behavior (i.e., relapse) is a key concern in most behavioral interventions. Resurgence refers to the reappearance of a previously rewarded behavior when reward for an alternative behavior is also discontinued. It is especially relevant to the reappearance of problem behavior because many behavioral interventions discontinue reward for aberrant behavior while simultaneously rewarding an appropriate response.

Understanding the underlying neuropharmacology of behavioral phenomena such as resurgence is important because it helps elucidate the neural processes at the root of such behavior, and also has implications for pharmacotherapies. Existing information about the neuropharmacology of resurgence is scarce, but …

Presence And Function Of Tetrodotoxin In Terrestrial Vertebrates And Invertebrates, Amber N. Stokes

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Tetrodotoxin (TTX) is a potent neurotoxin found in a variety of species. This toxin has long been of concern to human health as it is found in puffer fish, which are a delicacy in Japan. Since the distribution of this toxin is so great, there are many questions regarding the evolution and ecology of organisms that have TTX. My research has focused on further investigating three topics with this research: production, predation, and identification of novel TTX bearing taxa. In order to perform this research I first refined a Competitive Inhibition Enzymatic Immunoassay methodology to quantify levels of TTX in …

Utilizing Remote Sensing And Geospatial Techniques To Determine Detection Probabilities Of Large Mammals, Patricia A. Terletzky-Gese

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Whether a species is rare and requires protection or is overabundant and needs control, an accurate estimate of population size is essential for the development of conservation plans and management goals. Wildlife science has traditionally relied on human observers in airplanes, helicopter, or ground vehicles to count the number of individuals seen during wildlife surveys. However, these traditional surveys of wildlife require significant resources, are difficult to conduct quickly and safely over remote and/or extensive locations, are disruptive to the studied species, and are prone to significant error due to unobserved or missed animals and multiple counts of single animals. …

Characteristics Of 4-H Participants And Their Psychosocial Development, Lauralee Lyons

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Volunteerism is an important component in the 4-H program. It was initially used as a method to help agents reach the many youth interested in participating in 4-H. Community service has since become a required component for every club project. Research shows that volunteering can impact youth in many different ways. Other research shows that 4-H youth are more likely to contribute or do some type of community service.

The present study uses the Modified Extended Version of the Object Measure of Ego Identity Status (EOMEIS), the Cognitive Autonomy and Self-Evaluation (CASE) inventory, and an instrument specifically designed to study …

The Involvement Of Beta-Catenin In The Inflammatory Response Leading To Autoimmune Diabetes Development., Arin Lee Zirnheld

Electronic Theses and Dissertations

We identified and characterized a novel defect in β-catenin expression in bone marrow derived dendritic cells (BMDC) from NOD mice, a model for human Type I diabetes. This protein is expressed at high levels throughout the lifespan of the mouse and correlates with increased pro-inflammatory cytokine production by the BMDC and IFNγ induction by T cells cocultured with the BMDC. These defects, including a similar pattern of pro-inflammatory cytokine production, are also observed in human monocytederived DC from diabetic patients. After exploring several potential mechanisms involved in the accumulation of β-catenin in NOD BMDC, we found that β-catenin is phosphorylated …