Digital Commons Network^™

Lost Branches On The Tree Of Life, Bryan T. Drew, Romina Gazis, Patricia Cabezas, Kristen S. Swithers, Jiabin Deng, Roseana Rodriguez, Laura A. Katz, Keith A. Crandall, David S. Hibbett, Douglas E. Soltis

Biological Sciences: Faculty Publications

No abstract provided.

Niche Syndromes, Species Extinction Risks, And Management Under Climate Change, Dov F. Sax, Regan Early, Jesse Bellemare

Biological Sciences: Faculty Publications

The current distributions of species are often assumed to correspond with the total set of environmental conditions under which species can persist. When this assumption is incorrect, extinction risk estimated from species distribution models can be misleading. The degree to which species can tolerate or even thrive under conditions found beyond their current distributions alters extinction risks, time lags in realizing those risks, and the usefulness of alternative management strategies. To inform these issues, we propose a conceptual framework within which empirical data could be used to generate hypotheses regarding the realized, fundamental, and 'tolerance' niche of species. Although these …

Nutrient Requirements Of Beef Cattle, Edward Barrow Rayburn

Faculty & Staff Scholarship

WVU-Extension fact sheet

Brigham-Kanner Property Rights Conference Journal, Volume 2, William & Mary Law School

Brigham-Kanner Property Rights Journal

Interdisciplinary Perspectives on Property

October 11-12, 2012

Panel 1: The Impact of a Leading Property Scholar

Panel 3: Property Rights in Times of Economic Crisis

Panel 4: Property's Moral Dimension

Androgen Activity And Markers Of Inflammation Among Men In Nhanes Iii, Mary Schooling

Publications and Research

Objectives
Inflammation contributes to chronic diseases. Lower serum testosterone among men is associated with less inflammation, yet immune defense is thought to trade-off against reproduction with androgens adversely affecting immune function. Anti-androgens are effective at castrate levels of serum testosterone, suggesting serum testosterone may not capture all androgen activity. The association of two androgen biomarkers with key markers of inflammation was examined.

Methods
The adjusted association of serum testosterone and androstanediol glucuronide with Creactive protein, white blood cell, granulocyte and lymphocyte count, fibrinogen and hemoglobin, as a control outcome because testosterone administration raises hemoglobin, were examined in a nationally representative …

Pharmaceutical Efficacy: The Illusory Legal Standard , Jonathan J. Darrow

Washington and Lee Law Review

The very long and expensive process of new drug research and development might suggest to observers that the efficacy standard for drugs is elevated and substantial, but this is not the case. Under the U.S. Federal Food, Drug, and Co smetic Act, new drug approval merely requires that there be “substantial evidence that the drug will have the effect it purports or is represented to have.” While the evidence of effectiveness must therefore be substantial, the efficacy attested to by that evidence need not surpass any particular threshold (other than zero), thus allowing drugs with de minimis efficacy to be …

The Unsupportable Cost Of Variable Pricing Of Student Loans , Jonathan D. Glater

Washington and Lee Law Review

No abstract provided.

2013 September Newsletter, Nancy Rockey

Human Subject Research Archive

No abstract provided.

Molecular Characterization Of Tick Salivary Gland Glutaminyl Cyclase, Steven W. Adamson, Rebecca E. Browning, Chien-Chung Chao, Robert C. Bateman Jr., Wei-Mei Ching, Shahid Karim

Faculty Publications

Glutaminyl cyclase (QC) catalyzes the cyclization of N-terminal glutamine residues into pyroglutamate. This post-translational modification extends the half-life of peptides and, in some cases, is essential in binding to their cognate receptor. Due to its potential role in the post-translational modification of tick neuropeptides, we report the molecular, biochemical and physiological characterization of salivary gland QC during the prolonged blood feeding of the black-legged tick (Ixodes scapularis) and the gulf-coast tick (Amblyomma maculatum). QC sequences from I. scapularis and A. maculatum showed a high degree of amino acid identity to each other and other arthropods and …

Selected Bibliography For Work In Reading, Literacy, And Pedagogy, Geert Vandermeersche, Kris Rutten, Steven Tötösy De Zepetnek

CLCWeb: Comparative Literature and Culture

No abstract provided.

Evidence For 20th Century Climate Warming And Wetland Drying In The North American Prairie Pothole Region, Brett A. Werner, W. Carter Johnson, Glenn R. Guntenspergen

Natural Resource Management Faculty Publications

The Prairie Pothole Region (PPR) of North America is a globally important resource that provides abundant and valuable ecosystem goods and services in the form of biodiversity, groundwater recharge, water purification, flood attenuation, and water and forage for agriculture. Numerous studies have found these wetlands, which number in the millions, to be highly sensitive to climate variability. Here, we compare wetland conditions between two 30-year periods (1946–1975; 1976–2005) using a hindcast simulation approach to determine if recent climate warming in the region has already resulted in changes in wetland condition. Simulations using the WETLANDSCAPE model show that 20th century climate …

Evaluation Of Antiobesity Activity Of Fucus Vesiculosus, Vishnu Korukanti, Himabindu Ponnam, Butchi Akondi

Indian Journal of Research in Homoeopathy

Background and Aim: The drug Fucus vesiculosus is used in alternative system of medicine and homoeopathy, for the treatment of obesity. But in homoeopathic literature survey, we found no substantial pharmacological evidence to prove its safety and efficacy. So, the study was taken up on this drug and evaluated it on different animal models (diet-induced and chemical-induced models) of obesity. Material and Methods: Obesity was induced in adult female Wistar albino rats (100-120 g) by feeding the rats with cafeteria diet for 42 days in diet-induced model and by administration of single intraperitoneal injection of Triton X-100 in chemical-induced model. …

Ccrh Quarterly Bulletin, Volume 7 (1-4), (1985), Asha Chowdhry, Ritika Narula

Indian Journal of Research in Homoeopathy

No abstract provided.

Study Of A Molten Carbonate Fuel Cell Combined Heat, Hydrogen And Power System: End-Use Application, Tarek A. Hamad, Abdulhakim Amer A. Agll, Yousif M. Hamad, Sushrut Bapat, Mathew Thomas, Kevin B. Martin, John W. Sheffield

Engineering Management and Systems Engineering Faculty Research & Creative Works

To address the problem of fossil fuel usage and high greenhouse gas emissions at the Missouri University of Science and Technology campus, using of alternative fuels and renewable energy sources can lower energy consumption and greenhouse gas emissions. Biogas, produced by anaerobic digestion of wastewater, organic waste, agricultural waste, industrial waste, and animal by-products is a potential source of renewable energy. In this work, we have discussed the design of CHHP system for the campus using local resources. An energy flow and resource availability study is performed to identify the type and source of feedstock required to continuously run the …

Female Elk Contacts Are Neither Frequency Nor Density Dependent, P. C. Cross, T. G. Creech, Michael Ryan Ebinger, Kezia R. Manlove, K. Irvine, J. Henningsen, J. Rogerson, B. M. Scurlock, S. Creel

Wildland Resources Faculty Publications

Identifying drivers of contact rates among individuals is critical to understanding disease dynamics and implementing targeted control measures. We studied the interaction patterns of 149 female elk (Cervus canadensis) distributed across five different regions of western Wyoming over three years, defining a contact as an approach within one body length (∼2 m). Using hierarchical models that account for correlations within individuals, pairs, and groups, we found that pairwise contact rates within a group declined by a factor of three as group sizes increased 33-fold. Per capita contact rates, however, increased with group size according to a power function, such that …

Inside Earth, Volume 16, No. 2, Fall 2013, Andrea Croskrey, Cave And Karst Program (U.S.)

Inside Earth

Contents: Program Overview -- Preliminary NPS Cave and Karst Summaries -- Return to Oz -- Carbidimites in Wind Cave -- Park Updates

Ipulse: September 2013, Lynn University

Student Newspapers

Issues:

• September 19, 2013
• September 20, 2013
• September 23, 2013
• September 24, 2013
• September 25, 2013
• September 26, 2013
• September 27, 2013
• September 30, 2013

Rethinking The Worker Classification Test: Employees, Entrepreneurship, And Empowerment, Griffin Toronjo Pivateau

Northern Illinois University Law Review

The structure of the American workplace depends on the ability to distinguish between employees and independent contractors. Unfortunately, the law provides little to guide employers in classifying workers. The legal tests to determine worker status are confusing, yield inconsistent results, and are not suited to the evolving employment relationship. Traditionally, courts examine the amount of control exerted over the putative employee by the employer: The more control exerted by the employer over the work, the more likely it is that the worker will be considered an employee. Control, however, is not the only factor to examine in determining worker status. …

Re-Enchanting The World: An Examination Of Ethics, Religion, And Their Relationship In The Work Of Charles Taylor, David Mcpherson

Dissertations (1934 -)

In this dissertation I examine the topics of ethics, religion, and their relationship in the work of Charles Taylor. I take Taylor's attempt to confront modern disenchantment by seeking a kind of re-enchantment as my guiding thread. Seeking re-enchantment means, first of all, defending an `engaged realist' account of strong evaluation, i.e., qualitative distinctions of value that are seen as normative for our desires. Secondly, it means overcoming self-enclosure and achieving self-transcendence, which I argue should be understood in terms of transcending a `lower' mode of selfhood for a `higher' one in concern for `strong goods'.

One of the main …

Profile Synthesis Of Planar Variable Joints, Brian James Slaboch

Dissertations (1934 -)

Reconfigurable mechanisms provide quick changeover and reduced costs for low volume manufacturing applications. In addition, these mechanisms provide added flexibility in the context of a constrained environment. A subset of planar reconfigurable mechanisms use variable joints to provide this added adaptability.

In this dissertation, the profile synthesis of planar variable joints that change from a rotational motion to a translational motion was investigated. A method was developed to perform automated profile synthesis. It was shown that combinations of higher variable joints can be used to create kinematically equivalent variable joints that are geometrically different.

The results were used to create …

The Role Of Amp-Activated Protein Kinase In Mouse Oocyte Maturation And Subsequent Egg Activation, Ru Ya

Dissertations (1934 -)

Mammalian oogenesis begins during fetal development. Oocytes enter meiosis and arrest at prophase I before birth. Meiosis resumes after proper hormonal signaling, the oocyte completes meiosis I, and then ovulates in metaphase II, at which stage it arrests until fertilization occurs. Egg activation occurs upon sperm fertilization, which includes various physiological processes including calcium influx, release of cortical granules, and completion of meiosis II. However, egg activation can also occur without fertilization, which compromises the later embryonic development. The developmental period from prophase I to metaphase II is referred as oocyte maturation, and involves crucial dynamic change of the cytoskeleton …

Novel Paradigms For Visual Field Mapping With Functional Magnetic Resonance Imaging, Yan Ma

Dissertations (1934 -)

The overall goal of this study is to evaluate the existing, and develop new visual field mapping paradigms, which consist of visual stimulation scheme, post-processing and displaying tools using fMRI for both research and clinical applications.

We first directly compared phase mapping and random multifocal mapping paradigms with respect to clinically relevant factors. Multifocal mapping was superior in immunity to noise and was able to accurately decompose the response of single voxels to multiple stimulus locations. In contrast, phase mapping activated more extrastriate visual areas and was more efficient per run in achieving a statistically efficient response in a minimum …

2013 September Newsletter, Nancy Rockey

Life Renewal Archive

No abstract provided.

Neuropsychological Correlates Of Anosognosia In Mci And Dementia, Krystle Dina Barrera

Loma Linda University Electronic Theses, Dissertations & Projects

Anosognosia is a general term used to describe a lack of awareness of a disability and is well documented in various disorders associated with neurological compromise. While anosognosia is well documented as part and parcel to Alzheimer's dementia, less research has focused on determining the presence of anosognosia in what has come to be viewed as the subclinical precursor to dementia, mild cognitive impairment. In addition, a number of different methodologies and instruments are employed in quantifying and assessing anosognosia in various populations, which make comparison across studies and diagnoses difficult. Research commonly employs a paradigm that uses the discrepancy …

Cerebral Metabolic And Neuropsychological Outcomes Following Mild Traumatic Brain Injury, Julia L. Evans

Loma Linda University Electronic Theses, Dissertations & Projects

Traumatic brain injury (TBI) in adolescents and adults can result in cognitive, emotional, behavioral and neurological deficits that can persist more than a year after an injury. The current preliminary study used 3D magnetic resonance spectroscopic imaging (MRSI) and comprehensive neuropsychological assessment to determine if prolonged cerebral metabolic and cognitive alterations occur in individuals with persistent neurocognitive deficits following a mild TBI (mTBI). The current study evaluated the potential interactions between cerebral metabolism and neuropsychological performance, coping style, mood, and perceived quality of life in mTBI subjects with chronic post-concussive symptoms. The mTBI subjects performed worse than controls on neuropsychological …

Psychometrically Valid Relationships Between Acculturation And Neuropsychological Factors, Eunice E. Kwon

Loma Linda University Electronic Theses, Dissertations & Projects

Neuropsychological tests play a significant role in detecting brain dysfunction and treatment planning for patients. However, discrepancies in neurocognitive tests among ethnic minorities continue to perplex neuropsychologists and place ethnic minorities at a greater risk for misdiagnoses (Byrd et al., 2006). The aim of this study was to ascertain significant acculturation predictors influencing neuropsychological performance in ethnic minorities, particularly verbally mediated tasks which were known to be more susceptible to discrepancies in acculturation level were examined (Razani et al., 2007). Healthy participants from Hispanic (n = 52), Asian (n = 52), and Middle-Eastern (ME; n = 68) descents between the …

Never Smokers -- Are They More Sensitive To The Respiratory Health Effects Of Ambient Air Pollution?, Zuhair Saleh Natto

Loma Linda University Electronic Theses, Dissertations & Projects

Background: Several studies show an association between ambient particulate matter (PM) and all-cause mortality. The Adventist Health and Smog 1 (AHSMOG-1) study (N=6,338) has previously found associations between ambient air pollution and incident chronic obstructive pulmonary disease (COPD) using the spatial interpolation method from the three nearest fixed monitoring stations to residence and workplace. However, few studies have assessed the risk of death among disease specific subgroups such as those with COPD.

Objectives: The aims of this study were 1) to assess the effect of chronic exposure to ambient air pollutants on risk of all-cause mortality among persons with COPD …

Perceived Attitudes And Staff Roles Of Community Based Outpatient Clinics In Disaster Management, Pauline Antoinette Hodge-Hilton

Loma Linda University Electronic Theses, Dissertations & Projects

Objective: Natural and manmade disasters have claimed the lives of thousands of individuals in the US and caused billions of dollars in property damage. First responders carry the responsibility of disaster management, leaving other health care professionals such as medical clinic staff underutilized to support the clinic staff. We explored how medical and support staff in Community-based Outpatient VHA Clinics (CBOC) perceive their roles in disaster response, their attitudes about clinic readiness and continuity of care during disasters, and their ability to function in a post disaster environment.

Methods: A mixed method study was conducted to answer questions related to …

Role Of Vimf In Gingipain Maturation In Porphyromonas Gingivalis, Arun S. Muthiah

Loma Linda University Electronic Theses, Dissertations & Projects

Gingipain activity in Porphyromonas gingivalis, the major etiological agent in adult periodontitis, is post-translationally regulated by unique Vim proteins including VimF, a putative glycosyltransferase. To ascertain the VimF mediated phenotype we first inactivated the vimF gene in P. gingivalis ATCC 33277 (FLL476), a less virulent fimbriated strain. We observed that the vimF-defective mutant (FLL476) showed a phenotype similar to that of the vimF-defective mutant (FLL95) in the P. gingivalis W83 background. While hemagglutination was not detected and autoaggregationn was reduced, biofilm formation was increased in FLL476. Also, invasive capacity decreased for this mutant. Furthermore, fimbrial structures were missing in FLL476, …

Meta-Analysis Of Rodent Behavior In Various Brain Injury And Disease Models, Earl C. Thorndyke Iii

Loma Linda University Electronic Theses, Dissertations & Projects

The objective of this study was to identify patterns and profiles present in rodent behavioral assay data to inform methodology of future animal research. Domains of spatial learning, motor function, activity, and emotionality were examined. This study first identified how rodent performance on commonly used behavioral and neurocognitive assays varies by species, sex, and age. Significant differences were observed in spatial learning curves, patterns of motor function, emotionality and activity in rats and mice. Overall, males and females had similar performances on spatial learning and motor function, but sex and species interactions were also observed, indicating varied sex differences in …