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The Real Alfred Russel Wallace: Essays On An Outside-The-Box Thinker, Charles H. Smith

Faculty/Staff Personal Papers

Alfred Russel Wallace (8 January 1823 – 7 November 1913), English polymath and social critic, ranks high on the list of the most interesting characters in the history of science. Nevertheless, and despite a life filled with achievement, he has often been marginalized in the halls of learning. The truth is, Wallace was something of an “outside–the–box” thinker, and his many forays into the murkier areas of science and social science cost him a lot of potential supporters. Still others, while recognizing his intellectual talents in general, have looked at the full span of his work and interests as a …

The Social Network And The Crowdfund Act: Zuckerberg, Saverin, And Venture Capitalists' Dilution Of The Crowd, John S. (Jack) Wroldsen

Vanderbilt Journal of Entertainment & Technology Law

By virtue of Title III of the JOBS Act, signed into law on April 5, 2012, crowdfunding could become a powerful, even revolutionary, force to finance start-up companies. It democratizes entrepreneurs' access to seed capital and converts the masses of Internet users into potential retail venture capitalists. Many have cautioned, though, that crowdfunding poses serious investment risks of start-up companies failing, committing fraud, and being mismanaged. Accordingly, the JOBS Act includes numerous disclosure obligations designed to mitigate such downside risks.

But what has been overlooked, and what this Article analyzes from a venture capitalist perspective, is that even if a …

Bowman's Beanstalk: Patent Exhaustion In Self-Replicating Technologies, Zachary Loney

Vanderbilt Journal of Entertainment & Technology Law

The breakneck speed of innovation has once again brought uncertainty to the realm of patent law in the form of self-replicating technologies. Traditionally, the doctrine of patent exhaustion has provided a balance between the monopolistic powers of the patent holder and the consumer's freedom to utilize a purchased product without future interference. The rights holder receives compensation from the initial sale and retains the right to make and sell additional goods, while the consumer may use or resell their particular article without concern for additional fees or payments. Self-replicating technology blurs this line because a consumer's use inherently includes the …

When Time Becomes Distorted: A Narcissist's View, Kourtney Lechner

EWU Masters Thesis Collection

"Past research has shown that many factors influence an individual's ability to estimate time. One factor that has been researched extensively is personality traits. While a few studies have investigated the effects of narcissism traits on time estimation accuracy, only one study investigated the influence covert and overt narcissism on time estimation. Overt narcissists tend to be more explicit about their demands for attention, where as covert narcissists tend to be more implicit in their demands for attention and more introverted, and have feelings of inferiority. Previous research suggests that those who are entitled believe that their time is more …

The Blackfoot Demonstrative System: Function, Form, And Meaning, Shannon Scott Schupbach

Graduate Student Theses, Dissertations, & Professional Papers

This thesis presents a comprehensive analysis of the Blackfoot demonstrative system. Previous research on Blackfoot (Uhlenbeck 1938, Taylor 1969, Frantz 2009) identifies sixteen morphemes that make up demonstrative words in the language. I propose a demonstrative template that takes into account the fixed morpheme ordering observed in demonstrative forms. Based on the proposed template, I motivate the analysis of the suffix -ka as encoding motion towards the speaker as this accounts for its position together with the suffixes -ya, -ma, and -hka, each of which encode features of motion or visibility. In describing situational functions of each …

The Moral Layers Of Fracking: From Basic Rights And Obligations To Human Flourishing, Angela L. Hotaling

Graduate Student Theses, Dissertations, & Professional Papers

As it is currently being discussed, hydraulic fracturing or “fracking” is the unconventional method of drilling and extracting oil and natural gas. Fracking starts at the earth’s surface where the technology is created and the sites are constructed. The process continues downward: drills pierce thousands of feet vertically and then horizontally underground. Then, millions of gallons of water mixed with sand and chemicals (referred to as “fracking fluid” or “slick water”) are pumped at high pressure through the pipe so as to fracture shale deposits and release gas or oil. Whether to allow fracking and its associated industrial activity is …

The Sweet Grass Hills And Blackfeet Indians: Sacredness, Land, And Institutional Discrimination, Cassie Sheets

Graduate Student Theses, Dissertations, & Professional Papers

The Sweet Grass Hills of north-central Montana are part of the four Tribes of the Blackfoot Confederacy’s traditional territory and play a vital role in perpetuating Blackfeet culture. The Blackfeet Tribe of Montana was forced to sell the Sweet Grass Hills to the federal government in 1888 after the decimation of bison populations. In 1992, the first large-scale corporate mining proposal in the Sweet Grass Hills was proposed by Lehmann and Associates and Manhattan Mineral, Ltd. In response to public outcries, environmental impact statements were issued by the Bureau of Land Management, the agency that manages the area, and Secretary …

Household Organization In The Fur Trade Era: Socioeconomic And Spatial Organizations Of Housepit 54, Alexandra Christine Williams

Graduate Student Theses, Dissertations, & Professional Papers

Households are fundamental units of society that possess powerful explanatory potential; however, few studies have approached household organization during the critical contact period within the Mid-Fraser Canyon. The 2012 excavation of Bridge River’s Housepit 54 (HP 54) offers a rare opportunity to investigate such socioeconomic relationships and their spatial manifestations. Hypotheses structured with a household archaeology theoretical framework emphasize household socioeconomic strategies. The first hypothesis outlines a network strategy characterized by greater centralization of power, hierarchical complexity, and material-wealth that is reflected in residential units with individual features and disparate accumulations of prestige goods and high utility resources. Such floor …

The Effect Of A Cannabinoid Receptor 2 (Cb2) Agonist On Allergic Airway Inflammation In A Mouse Model Of Asthma, Soram Hong

Graduate Student Theses, Dissertations, & Professional Papers

Allergic asthma is a chronic inflammatory disease that affects approximately 300 million people worldwide. The health problem is compounded by the fact that the prevalence of the disease is increasing in the Western world. Thus, there is a continued need for new and improved therapies for the disease. Recently, it has become evident that cannabinoids have immunosuppressive properties and can be used as therapeutics for various inflammatory diseases. The main aim of this study was to explore the anti-inflammatory effects of CB2 agonists on allergic airway inflammation using a mouse model of asthma and resolve any mechanisms that underpin the …

Adolescent Sleep And Cellular Phone Use: Recent Trends And Implications For Research, Sue K. Adams, Jennifer F. Daly, Desirée N. Williford

Human Development and Family Science Faculty Publications

Adolescent sleep needs range from 8.5–10 hours per night, with older adolescents requiring less sleep than younger adolescents. On average, however, American adolescents receive between 7.5–8.5 hours of sleep per night, with many sleeping fewer than 6.5 hours on school nights. Cellular phone use is emerging as an important factor that interferes with both sleep quality and quantity, particularly as smartphones become more widely available to teens. This review paper has three objectives. First, we will describe adolescent sleep patterns and the effects of sleep deprivation on adolescent physical and mental health. Second, we will describe current trends in technology …

Michael Bergmann, Michael J. Murray, And Michael C. Rea, Eds., Divine Evil? The Moral Character Of The God Of Abraham, Paul Copan

Faith and Philosophy: Journal of the Society of Christian Philosophers

No abstract provided.

Looking Through Pascal's Window, John T. Mullen

Faith and Philosophy: Journal of the Society of Christian Philosophers

No abstract provided.

Durkheim's Internet: Social And Political Theory In Online Society, Ari Ezra Waldman

Articles & Chapters

While the Internet has changed dramatically since the early 1990s, the legal regime governing the right to privacy online and Internet speech is still steeped in a myth of the Internet user, completely hidden from others, in total control of his online experience, and free to come and go as he pleases. This false image of the “virtual self” has also contributed to an ethos of lawlessness, irresponsibility, and radical individuation online, allowing the evisceration of online privacy and the proliferation of hate and harassment.

I argue that the myth of the online anonym is not only false as a …

Slow Logo: Brand Citizenship In Global Value Networks, Margaret Chon

Faculty Articles

This article makes a case for a theoretical departure from dominant approaches to trademark law. It explains and then connects information capitalism to new governance through the heuristic of brand citizenship. Through these suggested analytical lenses, it examines a case study of ‘Big Fashion,’ which has become a highly concentrated industry focused almost solely on maximizing shareholder profit without regard to consumer, environment, or labor impact. It then concludes with some suggestions regarding the functions of brand citizenship in increasingly globalized markets where downward pressure on prices translates into greater global public “bads” often imposed upon the most vulnerable. For …

The Invention Of Asian Americans, Robert S. Chang

Faculty Articles

The essay begins by examining amicus briefs submitted in Fisher v. Texas by Asian American organizations in support of and in opposition to affirmative action. What does it mean when groups that purportedly protect, advance, and represent the interests of Asian Americans invoke the historical treatment of Asian Americans and present facts about Asian Americans but end up advocating for opposite outcomes? This Essay starts with the competing Asian American perspectives and assertions of authority expressed in these briefs to explore the theme of a Symposium at the UC Irvine School of Law, provocatively entitled, Reigniting Community: Strengthening the APA …

The Essence Of Antitrust: Protecting Consumers And Small Suppliers From Anticompetitive Conduct, John B. Kirkwood

Faculty Articles

The goals of antitrust law continue to be debated because there is no single goal that is unambiguously correct. There is one goal, however, that now commands wider support than any other: protecting consumers and small suppliers from anticompetitive conduct – conduct that creates market power, transfers wealth from consumers or small suppliers, and fails to provide them with compensating benefits. This goal is the predominant objective in the legislative histories, it is broadly supported by the American people, it is easier to administer than total welfare, and it is now espoused by the majority of courts. Proponents of total …

Cheaper Than A Slave: Indentured Labor, Colonialism And Capitalism, Tayyab Mahmud

Faculty Articles

The construct of free wage-labor, envisaged as consensual sale of labor-power by an autonomous and unencumbered individual in a market of juridical equals governed strictly by economic laws of supply and demand, is the bedrock of the purportedly universal category of labor under capitalism. However, this conceptual ensemble is an instance, yet again, of a particular masquerading as the universal – Europe’s autobiography passing for world history. It also underscores the divergence between mythologies and historical operations of capitalism. This article takes up the deployment of indentured labor from colonial India in plantation colonies across the globe for over a …

Drug Panics In The Twenty-First Century: Ecstasy, Prescription Drugs, And The Reframing Of The War On Drugs, Deborah Ahrens

Faculty Articles

The Supreme Court has failed to clarify this important procedural exception to the clear error standard. More than this, the Court has failed to explain why it refuses to apply independent judgment to all constitutional facts. The results of the differential treatment of these two legal concepts are: 1) Rule 52, and the Supreme Court’s approach to its constitutional fact exception is another type of denial of structural due process, preventing the legal norming of intentional discrimination jurisprudence; 2) institutional interests of doctrinal coherence and decisional accuracy are minimized in favor of reducing direct costs to the judicial system; 3) …

Greetings And Grievances: A Letter From Afghan Professors, Laurel Currie Oates

Seattle Journal for Social Justice

No abstract provided.

Funding Alaska Village Relocation Caused By Climate Change And Preserving Cultural Values During Relocation, Jason Iverson

Seattle Journal for Social Justice

No abstract provided.

Of Reasonableness, Fairness And The Public Interest: Judicial Review Of Copyright Board Decisions In Canada's Copyright Pentalogy, Graham Reynolds

All Faculty Publications

This paper focuses on judicial review of Copyright Board decisions in Canada’s copyright pentalogy (the five copyright law decisions handed down by the Supreme Court of Canada (SCC) on 12 July 2012). Part I briefly discusses the (recent) history of judicial review of decisions of the Copyright Board. Part II analyzes Abella J’s reasons for judgment in Alberta (Education) v Canadian Copyright Licensing Agency (Access Copyright), 2012 SCC 37 (Alberta (Education)) in light of Rothstein J’s implied suggestion, in his dissenting reasons, that Abella J applied a correctness standard of review as opposed to a reasonableness standard of review. Part …

Camouflage Mismatch In Seasonal Coat Color Due To Decreased Snow Duration: Will Snowshoe Hares Keep Up With Climate Change?, Marketa Zimova

Graduate Student Theses, Dissertations, & Professional Papers

As wild species face anthropogenic stressors, they will either adapt, shift their geographic range, or decline, perhaps towards extinction. The relative scope of these responses has not been well studied, especially for climate change where geographic range shifts and population declines have been widely discussed but the potential for adaptation mostly ignored. Adaptation to anthropogenic stressors can occur through phenotypic plasticity and/or evolution. My thesis first establishes, based on field studies of wild snowshoe hares, a novel and high-profile stressor directly linked to climate change. The stressor arises from a decrease in snow duration due to climate change, which causes …

Shifts In Caribou Calving Habitat And Space-Use, Daniella Johanna Dekelaita

Graduate Student Theses, Dissertations, & Professional Papers

The woodland caribou (Rangifer tarandus caribou) population in Newfoundland has been declining since the mid-1990s, and will likely continue to decline into the foreseeable future. This decrease in numbers has been accompanied by a large drop in recruitment. Predation is the primary cause of caribou calf mortality in Newfoundland, and since 2003, >80% of radio-collared calves died within the first 6 months of life. Two Newfoundland herds also have shifted their calving grounds over the past 15 to 20 years. Our objective was to investigate why these shifts have occurred. We analyzed female telemetry locations spanning 29 years, to delineate …

Identifying Environmental Factors Influencing Golden Eagle Presence And Reproductive Success, Ross H. Crandall

Graduate Student Theses, Dissertations, & Professional Papers

Declining populations of plant and animal species is a major concern threatening global biodiversity. If we want to conserve threatened species, we must understand the requirements of the species. Recent data suggests Golden Eagle populations in the Western United States are declining. Future threats from expanded energy development, habitat loss and climate change are also a concern. Apparent declines and perceived threats have caused management agencies to classify the Golden Eagle as a species of concern requiring the creation of conservation plans. Yet, an effective conservation plan is dependent on information that is currently lacking. To address this lack of …

Differentiation-Induced Changes In Antioxidant Capacity And Antioxidant Response In Sh-Sy5y Cells: Role Of Nrf2, Akua Afriyie Karikari

Graduate Student Theses, Dissertations, & Professional Papers

Organisms are exposed to reactive oxygen species from internal metabolism and environmental toxicant exposure, which have been linked to the initiation and progression of many neuronal diseases such as Alzheimer’s and Parkinson’s diseases. Exposure to reactive oxygen species are counterbalanced by antioxidant defense systems such as the Nrf2-ARE pathway, the primary regulator of endogenous antioxidant response. Whereas neuronal cells are post-mitotic and are particularly susceptible to oxidative stress because of high oxygen consumption, astrocytes are mitotic and rely more on glycolytic metabolism. In this study, the difference in antioxidant response and capacity in mitotic and post-mitotic cells were investigated using …

Late Developing Mammary Tumors And Hyperplasia Induced By A Low-Oncogenic Variant Of Mouse Mammary Tumor Virus (Mmtv) Express Genes Identical To Those Induced By Canonical Mmtv, Robert D. Bruno

School of Medical Diagnostics & Translational Sciences Publications

Background: The canonical milk-transmitted mouse mammary tumor virus (MMTV) of C3H mice (C3H-MMTV) rapidly induces tumors in 90% of infected animals by 8 months of age. Pro-viral insertions of C3H-MMTV into genomic DNA results in the overexpression of common core insertion site (CIS) genes, including Wnt1/10b, Rspo2, and Fgf3. Conversely, infection by either the endogenous Mtv-1 virus (in C3Hf) or the exogenous nodule-inducing virus (NIV) (in Balb/c NIV) induces premalignant mammary lesions and tumors with reduced incidence and longer latency than C3H-MMTV. Here, we asked whether Mtv-1/NIV affected the expression of core CIS genes.

Findings: We confirmed the presence of …

Embryonic Stem Cells Are Redirected To Non-Tumorigenic Epithelial Cell Fate By Interaction With The Mammary Microenvironment, Corinne A. Boulanger, Robert D. Bruno, David L. Mack, Monica Gonzales, Nadia P. Castro, David S. Salomon, Gilbert H. Smith

School of Medical Diagnostics & Translational Sciences Publications

Experiments were conducted to redirect mouse Embryonic Stem (ES) cells from a tumorigenic phenotype to a normal mammary epithelial phenotype in vivo. Mixing LacZ-labeled ES cells with normal mouse mammary epithelial cells at ratios of 1:5 and 1:50 in phosphate buffered saline and immediately inoculating them into epithelium-divested mammary fat pads of immune-compromised mice accomplished this. Our results indicate that tumorigenesis occurs only when normal mammary ductal growth is not achieved in the inoculated fat pads. When normal mammary gland growth occurs, we find ES cells (LacZ+) progeny interspersed with normal mammary cell progeny in the mammary epithelial structures. We …

Isolation And Characterization Of A New Family Of Cysteine Rich Proteins Involved In The Assembly Process Of Dragline Silk From The Black Widow Spider, Latrodectus Hesperus, Thanh Due Pham

University of the Pacific Theses and Dissertations

Spider silks are protein-based fibers that possess remarkable mechanical properties. Major ampullate silk, also referred to as dragline silk, is renowned for its high tensile strength, extensibility and toughness. Dragline silk is produced from a liquid spinning dope that undergoes chemical and physical changes during extrusion. To date, no proteins that participate in the assembly process of major ampullate silk proteins have been identified. The goal of this project is the identification of such protein products. De novo sequencing of peptides from in pollution tryptic digestion of black widow spider dragline silk identified several novel peptides that were not derived …

Rhob Controls Coordination Of Adult Angiogenesis And Lymphangiogenesis Following Injury By Regulating Vezf1-Mediated Transcription., Damien Gerald, Irit Adini, Sharon Shechter, Carole Perruzzi, Joseph Varnau, Benjamin Hopkins, Shiva Kazerounian, Peter Kurschat, Stephanie Blachon, Santosh Khedkar, Mandrita Bagchi, David Sherris, George C Prendergast, Michael Klagsbrun, Heidi Stuhlmann, Alan C Rigby, Janice A Nagy, Laura E Benjamin

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Mechanisms governing the distinct temporal dynamics that characterize post-natal angiogenesis and lymphangiogenesis elicited by cutaneous wounds and inflammation remain unclear. RhoB, a stress-induced small GTPase, modulates cellular responses to growth factors, genotoxic stress and neoplastic transformation. Here we show, using RhoB null mice, that loss of RhoB decreases pathological angiogenesis in the ischaemic retina and reduces angiogenesis in response to cutaneous wounding, but enhances lymphangiogenesis following both dermal wounding and inflammatory challenge. We link these unique and opposing roles of RhoB in blood versus lymphatic vasculatures to the RhoB-mediated differential regulation of sprouting and proliferation in primary human blood versus …

Letting Nature Work In The Pacific Northwest: A Manual For Protecting Ecosystem Services Under Existing Law, Robert L. Glicksman, Robert W. Adler, Daniel J. Rohlf, Robert R.M Verchick, Yee Huang

GW Law Faculty Publications & Other Works

In the decades since Congress and state legislatures passed most of the nation's most significant environmental laws, our knowledge about ecosystems has increased dramatically. As ecologists learn more about the complex and dynamic interactions that produce valuable ecosystem services, decisionmakers and advocates should adopt an ecosystem services approach to implementing laws that affect the environment. An ecosystem services approach integrates advances in ecology with the law. It fosters creative thinking about how to restructure laws and regulatory programs to mimic the connectedness of ecosystem functions. The approach requires performance-based evaluations to measure success or failure of management decisions, and it …