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2013

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The Impact Of Age And Executive Function On Susceptibility To Misinformation, Michelle Phillips-Meek Jan 2013

The Impact Of Age And Executive Function On Susceptibility To Misinformation, Michelle Phillips-Meek

Theses and Dissertations

The current study examined the impact of age and executive function on susceptibility to misinformation. A total of 41 healthy young (19-31) and older (59-77) adults were presented with visual misinformation in a paradigm originally used by Okado and Stark (2005). Participants then completed a recognition memory task while undergoing a functional magnetic resonance imaging (fMRI) scan. Participants also completed a series of cognitive measures used to assess executive function. Results showed that age and executive function were both significant predictors of recognition memory accuracy. Activity in brain regions associated with conflict processing was greater for accurate versus false memory …


Going Into The Word-Hoard: The Writing Process, Language, And Its Implications In The Poetry Of Medbh Mcguckian And Paul Muldoon, Elizabeth Peele Jan 2013

Going Into The Word-Hoard: The Writing Process, Language, And Its Implications In The Poetry Of Medbh Mcguckian And Paul Muldoon, Elizabeth Peele

Theses and Dissertations

As two prominent figures of Northern Irish poetry, Medbh McGuckian and Paul Muldoon are often discussed as being "difficult" and "oblique." However, I argue that this categorization of their poetry is too simplistic and overlooks the dissimilarities in their writing process and view of language, and ultimately, in their poetry itself. By going back to the fundamentals of their works, I claim that the basis for this dissimilarity is, in fact, a differing view of the founding blocks of poetic language. McGuckian sees syntax as being the important factor while Muldoon focuses on the individual lexical meaning of words. These …


Thermal Infrared Imaging: Instrumentation And Method Development, Wayne O'Brien Jan 2013

Thermal Infrared Imaging: Instrumentation And Method Development, Wayne O'Brien

Theses and Dissertations

A recently development thermal infrared camera system was improved by designing new components to downsize physical aspect and improve the instrument's performance. A new thermal infrared light source was developed and characterized. It is designed from a custom-made Macor backpiece that holds an alumina screw. High resistance wire is coiled around the screw. The coiled wire is covered with an alumina coating. Most light sources have a spectral emissivity similar to that of a blackbody emitter. This source has a spectral irradiance profile that is not similar to a blackbody source. Thus, the lamp has an improved efficiency in the …


Amaretto Breedables V. Ozimals, United States District Court For The Northern District Of California Jan 2013

Amaretto Breedables V. Ozimals, United States District Court For The Northern District Of California

Historical and Topical Legal Documents

No abstract provided.


The Aryl Hydrocarbon Receptor Regulates An Essential Transcriptional Element In The Immunoglobulin Heavy Chain Gene, Michael J. Wourms Jan 2013

The Aryl Hydrocarbon Receptor Regulates An Essential Transcriptional Element In The Immunoglobulin Heavy Chain Gene, Michael J. Wourms

Browse all Theses and Dissertations

2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is a ubiquitous environmental contaminant that inhibits immunoglobulin (Ig) expression and Ig heavy (IgH) chain gene transcription. Transcription of the IgH gene involves several regulatory elements including the 3'lgh regulatory region (3'lghRR) which is composed of four enhancers (hs3A, hs1,2, hs4, and hs3B). Dioxin responsive elements (DRE) in the hs4 and hs1,2 enhancers of the 3lghRR that bind the aryl hydrocarbon receptor (AhR), a ligand-activated transcription factor that regulates dioxin sensitive genes suggest that the 3'lghRR may be a transcriptional target of TCDD. The current study utilized an IgA secreting mouse …


Utility Of A Volume-Regulated Drive System For Direct Mechanical Ventricular Actuation, Benjamin A. Schmitt Jan 2013

Utility Of A Volume-Regulated Drive System For Direct Mechanical Ventricular Actuation, Benjamin A. Schmitt

Browse all Theses and Dissertations

Direct Mechanical Ventricular Actuation (DMVA) is a non-blood contacting cardiac assist device that augments ventricular function. The purpose of this study was to determine if a volume-regulated "hand pump" drive system and a pressure-regulated "switch tank" drive system provide equivalent levels of cardiac support. Canine (n=2) and swine (n=4) were instrumented for hemodynamic monitoring and intravascular echocardiography. DMVA support was assessed during both severe heart failure and fibrillation. Pump function was evaluated using hemodynamic measures to calculate stroke work. Myocardial function was assessed using echocardiographic speckle tracking to quantify strain rate. Results were compared between groups using paired t-tests. There …


Ambiguities Of Free Labor Revisited: The Convict-Labor Question In Progressive-Era New York, Barry Cushman Jan 2013

Ambiguities Of Free Labor Revisited: The Convict-Labor Question In Progressive-Era New York, Barry Cushman

Book Chapters

From the Author

Until the last quarter of the twentieth century it was a commonplace that the various expressions of economic substantive due process we associate with the so-called “Lochner Era” were animated by laissez-faire economics and Social Darwinism. More recent assessments have persuasively rejected this view, observing that the Court as a whole and the justices individually voted to uphold many more instances of government regulation of the economy than they voted to invalidate, and that the closest thing to a Social Darwinist that the Court had to offer was Justice Holmes, on whose polemical dissent in Lochner the …


Diminished Immigrants And Postnostalgia In Latin, Laala Al-Jaber Jan 2013

Diminished Immigrants And Postnostalgia In Latin, Laala Al-Jaber

Comparative Literature M.A. Essays

No abstract provided.


Certificates Of Confidentiality: Protecting Human Subject Research Data In Law And Practice, Leslie E. Wolf, Mayank J. Patel, Brett A. Williams, Jeffrey L. Austin, Lauren A. Dame Jan 2013

Certificates Of Confidentiality: Protecting Human Subject Research Data In Law And Practice, Leslie E. Wolf, Mayank J. Patel, Brett A. Williams, Jeffrey L. Austin, Lauren A. Dame

Minnesota Journal of Law, Science & Technology

No abstract provided.


Faculty Masthead, Mjlst Editorial Board Jan 2013

Faculty Masthead, Mjlst Editorial Board

Minnesota Journal of Law, Science & Technology

No abstract provided.


Reviews Of Science For Science Librarians: Drought In The Agricultural And Geosciences Literature, Leslie M. Delserone, Adonna Fleming Jan 2013

Reviews Of Science For Science Librarians: Drought In The Agricultural And Geosciences Literature, Leslie M. Delserone, Adonna Fleming

University of Nebraska-Lincoln Libraries: Faculty Publications

Drought is a hot topic, given the climatic events of summer 2012 in the United States. This article provides a fundamental understanding of drought—its definitions, classifications, ratings, and impact on agriculture. Also included are introductions to drought-related research areas in the geosciences—specifically geology, hydrology, and atmospheric sciences—as well as pointers to reliable sources of information about drought from the agricultural and geosciences literature.


Combinatorial Neural Codes From A Mathematical Coding Theory Perspective, Carina Curto, Vladimir Itskov, Katherine Morrison, Zachary Roth, Judy L. Walker Jan 2013

Combinatorial Neural Codes From A Mathematical Coding Theory Perspective, Carina Curto, Vladimir Itskov, Katherine Morrison, Zachary Roth, Judy L. Walker

Department of Mathematics: Faculty Publications

Shannon’s seminal 1948 work gave rise to two distinct areas of research: information theory and mathematical coding theory. While information theory has had a strong influence on theoretical neuroscience, ideas from mathematical coding theory have received considerably less attention. Here we take a new look at combinatorial neural codes from a mathematical coding theory perspective, examining the error correction capabilities of familiar receptive field codes (RF codes).We find, perhaps surprisingly, that the high levels of redundancy present in these codes do not support accurate error correction, although the error-correcting performance of receptive field codes catches up to that of random …


Dirofilariosis In The Americas: A More Virulent Dirofilaria Immitis?, Filipe Dantas-Torres, Domenico Otranto Jan 2013

Dirofilariosis In The Americas: A More Virulent Dirofilaria Immitis?, Filipe Dantas-Torres, Domenico Otranto

Harold W. Manter Laboratory of Parasitology: Library Materials

Dirofilarioses are widespread diseases caused by filarioid nematodes (superfamily Filarioidea) of the genus Dirofilaria, which are transmitted by a plethora of mosquito species. The principal agent of canine dirofilariosis in the Americas is Dirofilaria immitis, which may also occasionally infest humans, resulting in pulmonary nodules that may be confounded with malignant lung tumours. Because human cases of dirofilariosis by D. immitis are relatively frequent in the Americas and rare in Europe and other eastern countries, where Dirofilaria repens is the main causative agent, the existence of a more virulent strain of D. immitis in the Americas …


First Descriptions Of Dicyemid Mesozoans (Dicyemida: Dicyemidae) From Australian Octopus (Octopodidae) And Cuttlefish (Sepiidae), Including A New Record Of Dicyemennea In Australian Waters, Sarah R. Catalano Jan 2013

First Descriptions Of Dicyemid Mesozoans (Dicyemida: Dicyemidae) From Australian Octopus (Octopodidae) And Cuttlefish (Sepiidae), Including A New Record Of Dicyemennea In Australian Waters, Sarah R. Catalano

Harold W. Manter Laboratory of Parasitology: Library Materials

Three new species of dicyemid mesozoans are described for the first time from Australian octopus and cuttlefish species. Dicyemennea floscephalum sp. n. is described from Octopus berrima Stranks et Norman (southern keeled octopus) collected from Spencer Gulf and Gulf St. Vincent, South Australia, Australia and represents the first description of a species of Dicyemennea Whitman, 1883 from Australian waters. Dicyema papuceum sp. n. and D. furuyi sp. n. are described from Sepia papuensis Hoyle (Papuan cuttlefish) collected from Shark Bay, Western Australia, Australia. Dicyemennea floscephalum sp. n. is a medium to large species that reaches approximately 4.9 mm in …


Current Known Range Of The Platte River Caddisfly, Ironoquia Plattensis, And Genetic Variability Among Populations From Three Nebraska Rivers, Lindsay A. Vivian, Michael Cavallaro, Kate Kneeland, Erica Lindroth, W. Wyatt Hoback, Kerri M. Farnsworth-Hoback, Robert R. Harms, John E. Foster Jan 2013

Current Known Range Of The Platte River Caddisfly, Ironoquia Plattensis, And Genetic Variability Among Populations From Three Nebraska Rivers, Lindsay A. Vivian, Michael Cavallaro, Kate Kneeland, Erica Lindroth, W. Wyatt Hoback, Kerri M. Farnsworth-Hoback, Robert R. Harms, John E. Foster

Department of Entomology: Faculty Publications

The Platte River caddisfly (Ironoquia plattensis Alexander and Whiles 2000) was recently described from a warm-water slough along the Platte River in central Nebraska and was considered abundant at the type locality. Surveys of 48 sites in 1999 and 2004 found eight additional sites with this species on the Platte River. The caddisfly was not found at the type locality in 2004 and one additional site in 2007, presumably because of drought conditions. Because of its apparent rarity and decline, the Platte River caddisfly is a Tier I species in Nebraska. For this project, surveys for the caddisfly were …


Genetic Diversity And Relatedness Of The Mangrove Rhizophora Mangle L. (Rhizophoraceae) Using Amplified Fragment Polymorphism (Aflp) Among Locations In Florida, Usa And The Caribbean, M. Albrecht, K. M. Kneeland, E. Lindroth, John E. Foster Jan 2013

Genetic Diversity And Relatedness Of The Mangrove Rhizophora Mangle L. (Rhizophoraceae) Using Amplified Fragment Polymorphism (Aflp) Among Locations In Florida, Usa And The Caribbean, M. Albrecht, K. M. Kneeland, E. Lindroth, John E. Foster

Department of Entomology: Faculty Publications

Rhizophora mangle L. is a widespread mangrove species in theWestern Hemisphere. Mangrove habitat loss and their importance to coastal and reef ecosystems make greater understanding of their genetic structure useful for conservation and management. An amplified fragment polymorphism (AFLP) analysis was performed on samples from Florida and the Caribbean to discover the genetic structure present. R. mangle had variable genetic diversity not related to latitude; P ranged 7 %–92 %. Some other factor, perhaps human impact, has caused low genetic diversity in some populations. Across Florida R. mangle populations varied in genetic diversity with less diversity (Gst=0.195) and …


Dietary Supplementation With Pollen Enhances Survival And Collembola Boosts Fitness Of A Web-Building Spider, Jason M. Schmidt, Julie A. Peterson, Jonathan Lundgren, James D. Harwood Jan 2013

Dietary Supplementation With Pollen Enhances Survival And Collembola Boosts Fitness Of A Web-Building Spider, Jason M. Schmidt, Julie A. Peterson, Jonathan Lundgren, James D. Harwood

Department of Entomology: Faculty Publications

Uncertainties exist about the value of non-prey food for predators that are commonly food-limited, and the dietary conditions where non-prey foods are beneficial for carnivorous species. Prior studies show that large quantities of pollen grains are intercepted in the webs of web-building spiders. We examined the nutritional benefits of pollen as a non-prey food for a common ground-dwelling, sheet web-building spider, Mermessus fradeorum (Berland) (Araneae: Linyphiidae). These predators were provided diets of prey or no prey in the presence and absence of pollen. Treatment effects were quantified by measuring predator body nutrient composition, survival, body size, and offspring production. Per …


Bacillus Thuringiensis: Transgenic Crops, Julie A. Peterson, John J. Obrycki, James D. Harwood Jan 2013

Bacillus Thuringiensis: Transgenic Crops, Julie A. Peterson, John J. Obrycki, James D. Harwood

Department of Entomology: Faculty Publications

Bacillus thuringiensis (Bt) crops, genetically modified to express insecticidal toxins that target key pests of corn, cotton, rice, potato, and other crops, have been rapidly adopted and have become dominant fixtures in agroecosystems throughout the world. Due to the constitutive nature of Bt toxin expression, insecticidal proteins may be found in nearly all plant tissues, presenting multiple sources for Bt toxins to enter the environment, thus creating complex direct and indirect pathways for non-target organisms to be exposed to insecticidal proteins. The environmental impacts of Bt crops have been widely debated, although both benefits and risks do exist. Benefits of …


Inter- And Intraspecific Identification Of The Screwworm, Cochliomyia Hominivorax, Using Random Amplified Polymorphic Dna-Polymerase Chain Reaction, Steven R. Skoda, James L. Figarola, Saowaluck Pornkulwat, John E. Foster Jan 2013

Inter- And Intraspecific Identification Of The Screwworm, Cochliomyia Hominivorax, Using Random Amplified Polymorphic Dna-Polymerase Chain Reaction, Steven R. Skoda, James L. Figarola, Saowaluck Pornkulwat, John E. Foster

Department of Entomology: Faculty Publications

The screwworm, Cochliomyia hominivorax (Coquerel) (Diptera: Calliphoridae), is one of the most devastating arthropod pests of livestock in the Western Hemisphere. Early instars are very difficult to distinguish morphologically from several closely related blow fly species. Random amplified polymorphic DNA-polymerase chain reaction (RAPD-PCR) markers were developed for identifying C. hominivorax from other wound inhabiting species. Forty decameric primers were screened; nine showed clear reproducible RAPD profiles suitable for distinguishing all life stages of C. hominivorax from 7 other species, including C. macellaria (Fabricius). The results from RAPD-PCR with field-collected samples of unknown first instars agreed with morphological identification that the …


Predator Behavior In The Wild Web World Of Bugs: An Information Foraging Theory Perspective, Sandeep Kaur Kuttal, Anita Sarma, Gregg Rothermel Jan 2013

Predator Behavior In The Wild Web World Of Bugs: An Information Foraging Theory Perspective, Sandeep Kaur Kuttal, Anita Sarma, Gregg Rothermel

School of Computing: Conference and Workshop Papers

Web active end users often coalesce web information using web mashups. Web contents, however, tend to evolve frequently, and along with the black box nature of visual languages this complicates the process of debugging mashups. While debugging, end users need to locate faults within the code and then find a way to correct them; this process requires them to seek information related to web page content and behavior. In this paper, using an information foraging theory lens, we qualitatively study the debugging behaviors of 16 web-active end users. Our results show that the stronger scents available within mashup programming environments …


Real-Time Temporal Stereo Matching Using Iterative Adaptive Support Weights, Jedrzej Kowalczuk, Eric T. Psota, Lance C. Pérez Jan 2013

Real-Time Temporal Stereo Matching Using Iterative Adaptive Support Weights, Jedrzej Kowalczuk, Eric T. Psota, Lance C. Pérez

Department of Electrical and Computer Engineering: Faculty Publications

Stereo matching algorithms are nearly always designed to find matches between a single pair of images. A method is presented that was specifically designed to operate on sequences of images. This method considers the cost of matching image points in both the spatial and temporal domain. To maintain real-time operation, a temporal cost aggregation method is used to evaluate the likelihood of matches that is invariant with respect to the number of prior images being considered. This method has been implemented on massively parallel GPU hardware, and the implementation ranks as one of the fastest and most accurate real-time stereo …


Field Guide For Nebraska Invasive Insects, Nebraska Invasive Species Project Jan 2013

Field Guide For Nebraska Invasive Insects, Nebraska Invasive Species Project

Conservation and Survey Division: Faculty and Staff Publications

No abstract provided.


Diet-Induced Alterations Of Host Cholesterol Metabolism Are Likely To Affect The Gut Microbiota Composition In Hamsters, Inés Martínez, Diahann J. Perdicaro, Andrew W. Brown, Susan Hammons, Trevor J. Carden, Timothy P. Carr, Kent M. Eskridge, Jens Walter Jan 2013

Diet-Induced Alterations Of Host Cholesterol Metabolism Are Likely To Affect The Gut Microbiota Composition In Hamsters, Inés Martínez, Diahann J. Perdicaro, Andrew W. Brown, Susan Hammons, Trevor J. Carden, Timothy P. Carr, Kent M. Eskridge, Jens Walter

Department of Food Science and Technology: Faculty Publications

The gastrointestinal microbiota affects the metabolism of the mammalian host and has consequences for health. However, the complexity of gut microbial communities and host metabolic pathways make functional connections difficult to unravel, especially in terms of causation. In this study, we have characterized the fecal microbiota of hamsters whose cholesterol metabolism was extensively modulated by the dietary addition of plant sterol esters (PSE). PSE intake induced dramatic shifts in the fecal microbiota, reducing several bacterial taxa within the families Coriobacteriaceae and Erysipelotrichaceae. The abundance of these taxa displayed remarkably high correlations with host cholesterol metabolites. Most importantly, the associations …


Allergenicity Assessment Of A Genetically Modified Protein-Recombinant Human Lactoferrin, Cui Zhou, Na Sun, Jing Wang, Jing Lu, Jing Tian, Richard E. Goodman, Ning Li, Huilian Che, Kunlun Huang Jan 2013

Allergenicity Assessment Of A Genetically Modified Protein-Recombinant Human Lactoferrin, Cui Zhou, Na Sun, Jing Wang, Jing Lu, Jing Tian, Richard E. Goodman, Ning Li, Huilian Che, Kunlun Huang

Department of Food Science and Technology: Faculty Publications

Background: Recombinant human lactoferrin (rhLF) has previously suggested serving as food additive due to the natural iron binding properties that provide anti-microbial activity. Recombinant cows have been produced that express hLf in milk. However, the potential allergenicity of hLf has not been previously assessed. This research is conducted to evaluate the potential allergenicity of rhLF as a prerequisite for food use.

Methods: A comparison was made of the bioactivity, physicochemical properties and glycosylation profile between rhLF and natural hLF. The amino acid sequence of hLf was compared to known allergens. Additionally, the stability of hLf in pepsin and a human …


The Protein Structure Determines The Sensitizing Capacity Of Brazil Nut 2s Albumin (Ber E1) In A Rat Food Allergy Model, Jolanda H. M. Van Bilsen, Leon M.J. Knippels, Andre H. Penninks, Willem F. Nieuwenhuizen, Harmen H.J. De Jongh, Stef J. Koppelman Jan 2013

The Protein Structure Determines The Sensitizing Capacity Of Brazil Nut 2s Albumin (Ber E1) In A Rat Food Allergy Model, Jolanda H. M. Van Bilsen, Leon M.J. Knippels, Andre H. Penninks, Willem F. Nieuwenhuizen, Harmen H.J. De Jongh, Stef J. Koppelman

Department of Food Science and Technology: Faculty Publications

It is not exactly known why certain food proteins are more likely to sensitize. One of the characteristics of most food allergens is that they are stable to the acidic and proteolytic conditions in the digestive tract. This property is thought to be a risk factor in allergic sensitization. The purpose of the present study was to investigate the contribution of the protein structure of 2S albumin (Ber e1), a major allergen from Brazil nut, on the sensitizing capacity in vivo using an oral Brown Norway rat food allergy model. Disulphide bridges of 2S albumin were reduced and …


Combinatorial Evaluation Of In Vivo Distribution Of Polyanhydride Particle-Based Platforms For Vaccine Delivery, Latrisha K. Petersen, Lucas M. Huntimer, Katharine Walz, Amanda E. Ramer-Tait, Michael Wannemueler, Balaji Narasimhan Jan 2013

Combinatorial Evaluation Of In Vivo Distribution Of Polyanhydride Particle-Based Platforms For Vaccine Delivery, Latrisha K. Petersen, Lucas M. Huntimer, Katharine Walz, Amanda E. Ramer-Tait, Michael Wannemueler, Balaji Narasimhan

Department of Food Science and Technology: Faculty Publications

Several challenges are associated with current vaccine strategies, including repeated immunizations, poor patient compliance, and limited approved routes for delivery, which may hinder induction of protective immunity. Thus, there is a need for new vaccine adjuvants capable of multi-route administration and prolonged antigen release at the site of administration by providing a depot within tissue. In this work, we designed a combinatorial platform to investigate the in vivo distribution, depot effect, and localized persistence of polyanhydride nanoparticles as a function of nanoparticle chemistry and administration route. Our observations indicated that the route of administration differentially affected tissue residence times. All …


Pinto Beans (Phaseolus Vulgaris L.) As A Functional Food: Implications On Human Health, Cristiane R. S. Câmara, Carlos A. Urrea, Vicki Schlegel Jan 2013

Pinto Beans (Phaseolus Vulgaris L.) As A Functional Food: Implications On Human Health, Cristiane R. S. Câmara, Carlos A. Urrea, Vicki Schlegel

Department of Food Science and Technology: Faculty Publications

Most foods are considered functional in terms of providing nutrients and energy to sustain daily life, but dietary systems that are capable of preventing or remediating a stressed or diseased state are classified as functional foods. Dry beans (Phaseolus vulgaris L.) contain high levels of chemically diverse components (phenols, resistance starch, vitamins, fructooligosaccharides) that have shown to protect against such conditions as oxidative stress, cardiovascular disease, diabetes, metabolic syndrome, and many types of cancer, thereby positioning this legume as an excellent functional food. Moreover, the United States has a rich dry bean history and is currently a top producer …


Songbird Abundance In Native And Planted Grassland Varies With Type And Amount Of Grassland In The Surrounding Landscape, Stephen K. Davis, Ryan J. Fisher, Susan L. Skinner, Terry L. Shaffer, R. Mark Brigham Jan 2013

Songbird Abundance In Native And Planted Grassland Varies With Type And Amount Of Grassland In The Surrounding Landscape, Stephen K. Davis, Ryan J. Fisher, Susan L. Skinner, Terry L. Shaffer, R. Mark Brigham

United States Geological Survey, Northern Prairie Wildlife Research Center: Publications

Agriculture and wildlife conservation programs have converted vast amounts of cropland into grasslands planted with exotic species. Understanding how landscape context influences avian use of native and planted grasslands is essential for developing effective conservation strategies in agricultural landscapes. Our primary objective was to determine the extent to which the amount and type of grassland in the surrounding landscape influences the abundance of grassland songbird species on native and planted grassland parcels in southern Saskatchewan and Alberta, Canada. Bird abundance was more strongly influenced by the amount and type of grassland within 400 m of breeding parcels than at larger …


Evaluation Of Higher Plant Virus Resistance Genes In The Green Alga, Chlorella Variabilis Nc64a, During The Early Phase Of Infection With Paramecium Bursaria Chlorella Virus-1, Janet M. Rowe, David D. Dunigan, Guillaume Blanc, James R. Gurnon, Yuannan Xia, James L. Van Etten Jan 2013

Evaluation Of Higher Plant Virus Resistance Genes In The Green Alga, Chlorella Variabilis Nc64a, During The Early Phase Of Infection With Paramecium Bursaria Chlorella Virus-1, Janet M. Rowe, David D. Dunigan, Guillaume Blanc, James R. Gurnon, Yuannan Xia, James L. Van Etten

Nebraska Center for Virology: Faculty Publications

With growing industrial interest in algae plus their critical roles in aquatic systems, the need to understand the effects of algal pathogens is increasing. We examined a model algal host–virus system, Chlorella variabilis NC64A and virus, PBCV-1. C. variabilis encodes 375 homologs to genes involved in RNA silencing and in response to virus infection in higher plants. Illumina RNA-Seq data showed that 325 of these homologs were expressed in healthy and early PBCV-1 infected (≤60 min) cells. For each of the RNA silencing genes to which homologs were found, mRNA transcripts were detected in healthy and infected cells. C. variabilis …


‘‘Megavirales’’, A Proposed New Order For Eukaryotic Nucleocytoplasmic Large Dna Viruses, Philippe Colson, Xavier De Lamballerie, Natalya Yutin, Sassan Asgari, Yves Bigot, Dennis K. Bideshi, Xiao-Wen Cheng, Brian A. Federici, James L. Van Etten, Eugene V. Koonin, Bernard La Scola, Didier Raoult Jan 2013

‘‘Megavirales’’, A Proposed New Order For Eukaryotic Nucleocytoplasmic Large Dna Viruses, Philippe Colson, Xavier De Lamballerie, Natalya Yutin, Sassan Asgari, Yves Bigot, Dennis K. Bideshi, Xiao-Wen Cheng, Brian A. Federici, James L. Van Etten, Eugene V. Koonin, Bernard La Scola, Didier Raoult

Nebraska Center for Virology: Faculty Publications

The nucleocytoplasmic large DNA viruses (NCLDVs) comprise a monophyletic group of viruses that infect animals and diverse unicellular eukaryotes. The NCLDV group includes the families Poxviridae, Asfarviridae, Iridoviridae, Ascoviridae, Phycodnaviridae, Mimiviridae and the proposed family ‘‘Marseilleviridae’’. The family Mimiviridae includes the largest known viruses, with genomes in excess of one megabase, whereas the genome size in the other NCLDV families varies from 100 to 400 kilobase pairs. Most of the NCLDVs replicate in the cytoplasm of infected cells, within so-called virus factories. The NCLDVs share a common ancient origin, as demonstrated by evolutionary reconstructions that trace approximately 50 genes encoding …