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2013

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Effect Of Rat Strain Stereotactic Coordinates On Infarct Volume, Saagar K. Sanghvi Jan 2013

Effect Of Rat Strain Stereotactic Coordinates On Infarct Volume, Saagar K. Sanghvi

Browse all Theses and Dissertations

Ischemic stroke makes up 87% of all hospital-admitted stroke cases annually; the primary treatment for these cases is intravenous administration of tPA within a 3.5 hour window from stroke onset. A long-term delayed ischemic stroke treatment proposed by this study was a combination of the pharmaceuticals Fluoxetine (SSRI), Simvastatin (statin), and ascorbic acid (Vitamin C). 51 adult rat subjects (10-12 months of age; 44 Sprague Dawley, 7 Long Evans) were given a combination of the drugs for 31 days. Drugs were given through voluntary oral administration via sugar cookie-dough balls to reduce inhibition of neurogenesis through stress-related glucocorticoid production. Drug …

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Dangerous Feminine Sexuality: Biblical Metaphors And Sexual Violence Against Women, Lisa M. Ewing Jan 2013

Dangerous Feminine Sexuality: Biblical Metaphors And Sexual Violence Against Women, Lisa M. Ewing

Browse all Theses and Dissertations

This analysis responds to an ongoing debate between feminist and traditional readings of sexually violent (SV) metaphors in the prophetic texts of Hosea, Jeremiah, and Ezekiel, and the New Testament book of Revelation. Whereas feminist scholars have often argued that such metaphors are built upon the exploitation of women's sexuality, traditionalist scholars have insisted that the metaphors are merely literary devices that should only be read within their historical and literary contexts. Taking a moderate position, this analysis uses the cognitive metaphor theory to explain that the SV metaphors depend on cognitive associations of dangerous feminine sexuality to relate to …

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Analysis Of Human Echolocation Waveform For Radar Target Recognition, Kandarp Patel Jan 2013

Analysis Of Human Echolocation Waveform For Radar Target Recognition, Kandarp Patel

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Some blind humans have developed the remarkable capability of echolocation, similar to the type used by mammals such as the bat, dolphin and whale. This population of human has shown the ability to classify targets based on their location, size, shape and material in diverse environmental conditions simply by listening to the reflected echoes of tongue clicks generated by their mouth. To date, much of the research into human echolocation has been confined exclusively to behavioral science and the analysis is inconsistent with the approaches used in engineering. The waveforms used in current radar systems appear different to those typical …

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Enhancing Herbicide Efficacy On Reed Canary Grass (Phalaris Arundinacea) By Testing A Plant Growth Hormone, Application Times, And Herbicide Type, Denise Lynn Fong Jan 2013

Enhancing Herbicide Efficacy On Reed Canary Grass (Phalaris Arundinacea) By Testing A Plant Growth Hormone, Application Times, And Herbicide Type, Denise Lynn Fong

Browse all Theses and Dissertations

Phalaris arundinacea, also known as reed canary grass (RCG), is a non-native invasive grass that thrives in floodplains. RCG plants displace native flora which reduces diversity in otherwise species rich wetlands. This is a widespread problem throughout many parts of the USA. RCG can grow by its seeds or its rhizomes. Its seeds are capable of surviving long periods in soil. RCG can potentially be controlled by multi-year treatments in early spring and early fall with broad spectrum or grass specific herbicides. The goal of this study was to optimize methods to control RCG, in order to increase species …

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Hpai H5n1: A Global Pandemic Concern, With Implications For Pandemic Preperation And Public Health Policy, Lauren M. Koontz Jan 2013

Hpai H5n1: A Global Pandemic Concern, With Implications For Pandemic Preperation And Public Health Policy, Lauren M. Koontz

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Research on highly pathogenic avian influenza A (HPAI) H5N1 has gained much attention in recent years due to its devastating impact within the bird population. While transmission to humans is rare, infections are fatal in more than half of the cases. One of the main concerns among the scientific community is the ability for this virus to mutate in a way much like seasonal influeanza that would allow it to be transmitted efficiently among the human population. Two researchers were able to separately create mutant isolates of H5N1 influenza A virus that could be transmitted via the respiratory route between …

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Characterization Of Stimulation-Induced Volume Changes In The Ca1 Region Of Rat Hippocampus Slices, Amanda Brooke Gutwein Jan 2013

Characterization Of Stimulation-Induced Volume Changes In The Ca1 Region Of Rat Hippocampus Slices, Amanda Brooke Gutwein

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Intrinsic optical signals (IOS) were used to evaluate volume regulation mechanisms during Schaffer collateral stimulation-induced volume changes in hippocampal slices. The effects of stimulation frequency, synaptic function, ionotropic glutamate receptor (iGluR) activation, glutamate uptake, and volume regulatory anion channels (VRAC) were examined with IOS. Data were analyzed using ANOVA with Dunnett's post hoc test (p<0.05 indicated significance). IOS changes were stimulation frequency dependent between 1 Hz and 10 Hz with full recovery of IOS within 5 min. Synaptic blockage reduced the rate of swelling by 81% compared to the control and the IOS did not fully recover. Recovery rate was reduced with iGluR inhibition. Inhibition of glutamate uptake reduced the rate of swelling by 70% compared to vehicle controls. During stimulation, action potentials, iGluR activation, and glutamate uptake contribute to swelling. Regulatory volume mechanisms during stimulation were glutamate-mediated via iGluRs and VRAC independent.

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Palaeoecological Analysis Of The Decline In Stromatolite Abundance During The Ordovician Period, Noran Mhm El-Sherif Jan 2013

Palaeoecological Analysis Of The Decline In Stromatolite Abundance During The Ordovician Period, Noran Mhm El-Sherif

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A stromatolite is a laminated benthic microbial deposit. Its uniqueness arises from being present since the Precambrian to the present. Stromatolites recorded a peak time during the Mesoproterozoic, subsequently they witnessed abrupt rises and falls in abundance with the steepest decline in the Ordovician period, from which it never recovered from. There is no consensus yet regarding the reasons behind the decline of stromatolites. Thus the decline of these microbial deposits remains an enigma. Additionally, a literature gap exists regarding the reasons that specifically led to the Ordovician decline. Accordingly, the focus of this literature-based MSc. thesis is to find …

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New Insights Into The Spinal Recurrent Inhibitory Pathway Normally And After Motoneuron Regeneration, Ahmed Zayed Obeidat Jan 2013

New Insights Into The Spinal Recurrent Inhibitory Pathway Normally And After Motoneuron Regeneration, Ahmed Zayed Obeidat

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Despite more than seven decades of intensive research, uncertainty is the hallmark of spinal recurrent inhibition. The simplest possible structure that is formed between the a-motoneuron and its inhibitory interneurons has been the subject of long lasting scientific debate. To date, there is no consensus on the functional significance of this circuit. Even the simplest assumption of a negative feedback loop does not hold true. The current work used the technique of in vivo intracellular recording from the adult rat a-motoneurons to study the normal function and the plasticity after nerve injury and regeneration of this simple, yet intricate spinal …

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Tolfenamic Acid Induces Cell Apoptosis And Inhibits Collagen Accumulation In Keloid Fibroblasts, Dan Yi Jan 2013

Tolfenamic Acid Induces Cell Apoptosis And Inhibits Collagen Accumulation In Keloid Fibroblasts, Dan Yi

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Keloid scar is a fibroproliferative disorder which results from the accumulation of collagen through the activation of TGF-B/Smad signaling. Tolfenamic acid (TA) has been found to inhibit collagen synthesis in animal and induce cancer cell apoptosis. In this study, we investigated the effect of DMSO on cell apoptosis, TA on collagen deposition, and TA on collagen type I and smad2 protein expression in human normal fibroblasts (NFs) and human keloid fibroblasts (KFs). In the dose- and exposure time- response assays, we found that 1% DMSO for 48h treatment did not obviously induce NF and KF apoptosis and that 0.55x10-3 M …

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The Case For A Custer Battalion Survivor: Private Gustave Korn's Story, Albert Winkler Jan 2013

The Case For A Custer Battalion Survivor: Private Gustave Korn's Story, Albert Winkler

Faculty Publications

Almost all of these claims of men having survived Custer’s Massacre at the Battle of the Little Bighorn have proven to be false, Gustave Korn’s case has merit. He was with Company I of Custer’s Battalion when it was attacked and later overwhelmed by the Indians. Korn claimed that his horse was wounded, became unmanageable, and carried him away from the Custer’s Battalion before it was wiped out. The circumstantial evidence supports his claim, and many of the other men in the Seventh Cavalry believed him. Korn was also famous because he cared for Comanche, the horse that was badly …

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Grassroots Gay Rights: Legal Advocacy At The Local Level, Lydia E. Lavelle Jan 2013

Grassroots Gay Rights: Legal Advocacy At The Local Level, Lydia E. Lavelle

American University Journal of Gender, Social Policy & the Law

No abstract provided.

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John Kenneth Galbraith, Alexander J. Field Jan 2013

John Kenneth Galbraith, Alexander J. Field

Economics

Galbraith, John Kenneth (15 Oct. 1908-29 Apr. 2006), economist and author, was born in Iona Station, Ontario, Canada, to Archibald Galbraith and Sarah Catherine Kendall. Galbraith, who advanced and reinterpreted institutionalist and Keynesian traditions in economics while promoting a liberal and progressive political agenda, was arguably the best-known and most influential economist and public intellectual of his generation. He published dozens of books, served in a number of high-level government positions, and, as a faculty member at Harvard University for more than a quarter of a century, advised every Democratic president from Franklin Roosevelt to Bill Clinton. Galbraith's political education …

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Protecting Elites: An Alternative Take On How United States V. Jones Fits Into The Court's Technology Jurisprudence, Tamara Rice Lave Jan 2013

Protecting Elites: An Alternative Take On How United States V. Jones Fits Into The Court's Technology Jurisprudence, Tamara Rice Lave

Articles

This Article argues that the Supreme Court's technology jurisprudence can be best understood as protecting the privacy interest of elites. After providing an overview of the major technology cases from Olmstead to Kyllo, the Article focuses on the recent case of United States v Jones. The Article does not contend that the Court intended to protect elites, but instead posits that this motive likely operated at a more unconscious level because of the Justices' greater relative affluence and elevated social position.

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The "Friend"Ly Lawyer: Professionalism And Ethical Considerations Of The Use Of Social Networking During Litigation, Nicola A. Boothe-Perry Jan 2013

The "Friend"Ly Lawyer: Professionalism And Ethical Considerations Of The Use Of Social Networking During Litigation, Nicola A. Boothe-Perry

University of Florida Journal of Law & Public Policy

No abstract provided.

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Theological Foundations: Fiftieth Anniversary Scholarly Essays, Members Of The Seminary Faculty Jan 2013

Theological Foundations: Fiftieth Anniversary Scholarly Essays, Members Of The Seminary Faculty

Heritage Material

No abstract provided.

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A Short History Of Asbury Theological Seminary, Howard Fenimore Shipps Jan 2013

A Short History Of Asbury Theological Seminary, Howard Fenimore Shipps

Heritage Material

No abstract provided.

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The Subtle Intracapsular Survival Of The Fittest: Maternal Investment, Sibling Conflict, Or Environmental Effects?, Kathryn E. Smith, Sven Thatje Jan 2013

The Subtle Intracapsular Survival Of The Fittest: Maternal Investment, Sibling Conflict, Or Environmental Effects?, Kathryn E. Smith, Sven Thatje

Ocean Engineering and Marine Sciences Faculty Publications

Developmental resource partitioning and the consequent offspring size variations are of fundamental importance for marine invertebrates, in both an ecological and evolutionary context. Typically, differences are attributed to maternal investment and the environmental factors determining this; additional variables, such as environmental factors affecting development, are rarely discussed. During intracapsular development, for example, sibling conflict has the potential to affect resource partitioning. Here, we investigate encapsulated development in the marine gastropod Buccinum undatum. We examine the effects of maternal investment and temperature on intracapsular resource partitioning in this species. Reproductive output was positively influenced by maternal investment, but additionally, temperature and …

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Render Unto Rawls: Law, Gospel, And The Evangelical Fallacy, Wayne R. Barnes Jan 2013

Render Unto Rawls: Law, Gospel, And The Evangelical Fallacy, Wayne R. Barnes

University of Florida Journal of Law & Public Policy

No abstract provided.

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The Effect Of Bmi On The Age Of Menarche In Adolescent Girls, Samara R. Sterling Jan 2013

The Effect Of Bmi On The Age Of Menarche In Adolescent Girls, Samara R. Sterling

Master's Theses

Problem. Over the past century, the age of menarche has consistently declined in the United States and globally. Obesity has also increased by 82% globally over the past 20 years. Obesity, as measured by BMI percentiles in children, may contribute to the declining age of menarche. -- Method. Adolescent girls ages 12-19 were examined in California and Michigan. Physical development and the age of menarche were assessed through an online questionnaire. Height and weight measurements were taken at a clinic and converted to BMI percentile values. -- Results. A negative correlation was observed between BMI percentile values and the age …

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Government Of Western Australia Department Of Fisheries Annual Report 2012/13, Government Of Western Australia Department Of Fisheries Jan 2013

Government Of Western Australia Department Of Fisheries Annual Report 2012/13, Government Of Western Australia Department Of Fisheries

Department of Fisheries Annual Reports

This annual report provides an overview of the Department and its operations for the financial year ended 30 June 2013. It has been prepared in accordance with the requirements of the Financial Management Act 2006, the Fish Resources Management Act 1994 and the Public Sector Commission’s Annual reporting framework – 2012/13 reporting year.

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Matrigel Modulates A Stem Cell Phenotype And Promotes Tumor Cell Formation In A Mantle Cell Lymphoma Cell Line, Abigail Hielscher, Timothy Mcguire, Dennis Weisenburger, John Graham Sharp Jan 2013

Matrigel Modulates A Stem Cell Phenotype And Promotes Tumor Cell Formation In A Mantle Cell Lymphoma Cell Line, Abigail Hielscher, Timothy Mcguire, Dennis Weisenburger, John Graham Sharp

PCOM Scholarly Works

Tumors may be maintained by subpopulations of cells possessing stem cell-like properties. We evaluated the stem cell-like and tumor-forming properties of side population (SP) and CD133+/ CD44+ cells in Granta 519, a human mantle cell lymphoma cell line. The in-vitro Cobblestone Area Forming Cell (CAFC) assay, designed to detect stem and progenitor cells, revealed that SP cells contained the greatest proportion of stem cell-like cells. The addition of Matrigel to CAFC assays of SP and non-SP cells both increased their respective stem cell frequencies in comparison to those cultures without Matrigel, and additionally resulted in observed stem cell frequencies which …

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Hypoxia Affects The Structure Of Breast Cancer Cell Derived Matrix To Support Angiogenic Responses Of Endothelial Cells, Abigail Hielscher, Connie Qiu, Josh Porterfield, Quinton Smith, Sharon Gerecht Jan 2013

Hypoxia Affects The Structure Of Breast Cancer Cell Derived Matrix To Support Angiogenic Responses Of Endothelial Cells, Abigail Hielscher, Connie Qiu, Josh Porterfield, Quinton Smith, Sharon Gerecht

PCOM Scholarly Works

Hypoxia, a common feature of the tumor environment and participant in tumor progression, is known to alter gene and protein expression of several Extracellular Matrix (ECM) proteins, many of which have roles in angiogenesis. Previously, we reported that ECM deposited from co cultures of Neonatal Fibroblasts (NuFF) with breast cancer cells, supported 3-dimensional vascular morphogenesis. Here, we sought to characterize the hypoxic ECM and to identify whether the deposited ECM induce angiogenic responses in Endothelial Cells (ECs). NuFF and MDAMB 231 breast cancer cells were co-cultured, subjected to alternating cycles of 24 hours of 1% (hypoxia) and 21% (atmospheric) oxygen …

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Grappling With Issues Of Learning Science From Everyday Experiences: An Illustrative Case Study, A.-L. Tan, M. Kim, F. Talaue Jan 2013

Grappling With Issues Of Learning Science From Everyday Experiences: An Illustrative Case Study, A.-L. Tan, M. Kim, F. Talaue

Journal of Mathematics and Science: Collaborative Explorations

There are different perceptions among researchers with regard to the infusion of everyday experience in the teaching of science: 1) it hinders the learning of science concepts; or, 2) it increases the participation and motivation of students in science learning. This article attempts to contemplate those different perspectives of everyday knowledge in science classrooms by using everyday contexts to teach grade 3 science in Singapore. In this study, two groups of grade 3 students were presented with a scenario that required them to apply the concept of properties of materials to design a shoe. Subsequently, the transcripts of classroom discussions …

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The Cellular Nucleic Acid Binding Protein In Aging And Disease, Robin Webb Jan 2013

The Cellular Nucleic Acid Binding Protein In Aging And Disease, Robin Webb

Theses and Dissertations--Molecular and Cellular Biochemistry

The ZNF9 gene on chromosome 3 encodes the cellular nucleic acid binding protein (CNBP), a ubiquitously expressed, 177 amino acid (≈19.5kDa) protein that is highly conserved among vertebrates. The function of the protein is largely unknown, however an expansion in the first intron of the protein results in myotonic dystrophy type 2 (DM2), a multisystemic disease featuring cardiac arrhythmia, muscle wasting, cataracts, and a range of neuropathologies. Remarkably, we recently discovered that CNBP is involved in regulating the activity of β-secretase, the enzyme that produces the first cleavage event in the generation of the amyloid-β peptide (Aβ). The progressive fibrillization …

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The Regulation And Packaging Of Synaptic Vesicles Related To Recruitment Within Crayfish And Fruit Fly Neuromuscular Junctions: Variations In Low- And High-Output Terminals, Wenhui Wu Jan 2013

The Regulation And Packaging Of Synaptic Vesicles Related To Recruitment Within Crayfish And Fruit Fly Neuromuscular Junctions: Variations In Low- And High-Output Terminals, Wenhui Wu

Theses and Dissertations--Biology

Glutamate is the main excitatory neurotransmitter in the CNS and at the neuromuscular junctions (NMJs) of invertebrate. The characteristic similarities to CNS glutamatergic synapses in vertebrate and the anatomical simplicity of invertebrate NMJs favor the investigation of glutamatergic synaptic functions in this system. This dissertation mainly aimed to physiologically separate two functional vesicle groups, the reserve pool (RP) and readily releasable pool (RRP) within presynaptic nerve terminals of Procambarus Clarkii and Drosophila melanogaster. This was addressed in part by blocking the vesicular glutamate transporter (VGlut) with bafilomycin A1. Various frequencies of motor nerve stimulation, exposure time, and concentration of …

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Factors Influencing The Establishment And Survival Of Native Hardwood Tree Seedlings Of The Kentucky Inner Bluegrass Blue Ash-Oak Savanna-Woodland, James D. Shaffer Jan 2013

Factors Influencing The Establishment And Survival Of Native Hardwood Tree Seedlings Of The Kentucky Inner Bluegrass Blue Ash-Oak Savanna-Woodland, James D. Shaffer

Theses and Dissertations--Biology

Historically, the Kentucky Inner Bluegrass blue ash-oak savanna-woodland was the primary ecosystem of the Inner Bluegrass Region (IBR) of Kentucky. After European settlement, the majority (>99%) of Bluegrass savanna was converted to agricultural and urban land uses. Currently remnant savanna tree species are failing to recruit. Therefore, a long-term restoration ecology project researching competition and disturbance on seedling establishment, survival, and growth has been established at Griffith Woods (the largest remaining savanna in Kentucky) in Harrison Co., KY. Fourteen native hardwood tree species (a total of 6,168 seedlings) have been experimentally planted. Light, soil, surrounding vegetation, and herbivory, factors …

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Panel I: Critical Legal Studies In Intellectual Property And Information Law Scholarship, Peter Goodrich, Sonia K. Katyal, Rebecca Tushnet Jan 2013

Panel I: Critical Legal Studies In Intellectual Property And Information Law Scholarship, Peter Goodrich, Sonia K. Katyal, Rebecca Tushnet

Cardozo Arts & Entertainment Law Journal

No abstract provided.

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Protecting Post-Mortem Privacy: Reconsidering The Privacy Interests Of The Deceased In A Digital World, Lilian Edwards, Edina Harbina Jan 2013

Protecting Post-Mortem Privacy: Reconsidering The Privacy Interests Of The Deceased In A Digital World, Lilian Edwards, Edina Harbina

Cardozo Arts & Entertainment Law Journal

No abstract provided.

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An Essay In Honor Of Robert Sedler: Fierce Champion Of Free Speech, Joel Gora Jan 2013

An Essay In Honor Of Robert Sedler: Fierce Champion Of Free Speech, Joel Gora

Faculty Scholarship

No abstract provided.

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Voluntary Recalls, Anita Bernstein Jan 2013

Voluntary Recalls, Anita Bernstein

Faculty Scholarship

No abstract provided.

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