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Novel Design Of Functionalized Carbon Nanotube Electrodes And Membranes For Fuel Cells And Energy Storage, Xin Su

Theses and Dissertations--Chemical and Materials Engineering

A novel electrochemical method to generate nm-scale bubbles at the tips of CNTs can temporarily block the membrane. A 92% blocking efficiency is achieved when the bubbles are stabilized in 30-60 nm diameter „wells‟ at the tips of CNTs. This well is formed by the electrochemical oxidation of the conductive CNTs partially into the polymer matrix of the membrane. Meanwhile, the nanoscale bubbles can be removed with 0.004 atm pressure to recover the transport through the CNT membrane. The CNT membrane with nanoscale bubble valve system was used to demonstrate electrochemical energy storage.

Uniform ultrathin Pt films were electrodeposited onto …

Protein Based Biomimetic Approachs To Surface Hemocompatibility And Biocompatibility Enhancement, Matthew Thomas Dickerson

Theses and Dissertations--Chemical and Materials Engineering

T. pallidum can survive a primary immune response and continue growing in the host for an extended period of time. T. pallidum is thought to bind serum fibronectin (FN) through Tp0483 on the surface to obscure antigens. A Tp0483 fragment (rTp0483) was adsorbed onto functionalized self-assembled monolayers (SAMs) with FN. FN capture by adsorbed rTp0483 depended greatly on surface chemistry with COO- groups being best for FN binding. Hemocompatibility was determined by analysis of plasma protein adsorption, intrinsic pathway activation, and platelet activation. rTp0483+FN bound an equal or lesser amount of fibrinogen (Fg), human serum albumin (HSA), and factor XII …

Effect Of Ionic Surfactants On Electrostatic Charging Of Spray Droplets, Mark T. Warren

Theses and Dissertations--Chemical and Materials Engineering

Dust capture for small coal particles (<2.5µm) can be improved if one takes advantage of electrostatic charges that resides on the surface of coal dust particles and on the surface of water spray droplets used to capture coal dust. Traditional dust capture methods that use water sprays are ineffective in capturing small dust particles since the motion of small dust particles is governed by electrostatic forces. If additives such as ionic surfactants could be added to water that would enhance the surface charge on water spray droplets, dust capture with water sprays could be improved.

The results presented show that n-sodium octyl sulfate causes the greatest charge enhancement versus the longer chained n-sodium dodecyl sulfate and n-sodium octadecyl sulfate. This can be explained by considering the factors that lead to droplet charge enhancement. Those factors are the mass of surfactant ions at the droplet surface, and the diffusion rate of the surfactant ions from the bulk droplet to the surface of the droplet. Sodium octyl sulfate will have a faster diffusion rate to the droplet surface because of its relatively short length, and will also maximize the mass …

Nanoparticle Additives For Multiphase Systems: Synthesis, Formulation And Characterization, Vinod Kanniah

Theses and Dissertations--Chemical and Materials Engineering

Study on nanoparticle additives in multiphase systems (liquid, polymer) are of immense interest in developing new product applications. Critical challenges for nanoparticle additives include their synthesis, formulation and characterization. These challenges are addressed in three application areas: nanofluids for engine lubrication, ultrathin nanocomposites for optical devices, and nanoparticle size distribution characterization.

Nanoparticle additives in oligomer mixtures can be used to develop extended temperature range motor oils. A model system includes poly(α-olefin) based oligomers with a modest fraction of poly(dimethylsiloxane) oligomers along with graphite as nanoparticle additive. Partition coefficients of each oligomer are determined since the oligomer mixture phase separated at …

Fabrication Of An Epithelial Cell-Based Ion-Selective Electrode And Its Application For Use As Alternative Tumor Angiogenesis Assay, Christina Nicole Simmons

Theses and Dissertations--Chemical and Materials Engineering

Previous studies have provided evidence that endothelial cell-based potassium ion selective electrodes possess the ability to quantify substances that have permeability-altering effects on those endothelial cells. The capability of these so-called biosensors to detect elevated concentrations of certain chemical agents found following tumor formation make them useful in the application as an alternative tumor angiogenesis assay. In this study an epithelial cell line, human colon adenocarcinoma epithelial cells (Caco-2), was used to fabricate membranes that were used to test concentrations of these chemical agents, known as cytokines, mimicking the concentrations that have been observed in the serum of healthy individuals …

Biodegradable Hydrogels And Nanocomposite Polymers: Synthesis And Characterization For Biomedical Applications, Ashley Marie Hawkins

Theses and Dissertations--Chemical and Materials Engineering

Hydrogels are popular materials for biological applications since they exhibit properties like that of natural soft tissue and have tunable properties. Biodegradable hydrogels provide an added advantage in that they degrade in an aqueous environment thereby avoiding the need for removal after the useful lifetime. In this work, we investigated poly(β-amino ester) (PBAE) biodegradable hydrogel systems. To begin, the factors affecting the macromer synthesis procedure were studied to optimize the reproducibility of the resulting hydrogels made and create new methods of tuning the properties. Hydrogel behavior was then tuned by altering the hydrophilic/hydrophobic balance of the chemicals used in the …

Understanding Degradation And Lithium Diffusion In Lithium Ion Battery Electrodes, Juchuan Li

Theses and Dissertations--Chemical and Materials Engineering

Lithium-ion batteries with higher capacity and longer cycle life than that available today are required as secondary energy sources for a wide range of emerging applications. In particular, the cycling performance of several candidate materials for lithium-ion battery electrodes is insufficient because of the fast capacity fading and short cycle life, which is mainly a result of mechanical degradation.

This dissertation mainly focuses on the issue of mechanical degradation in advanced lithium-ion battery electrodes. Thin films of tin electrodes were studied where we observed whisker growth as a result of electrochemical cycling. These whiskers bring safety concerns because they may …

Application Of Thin Film Analysis Techniques And Controlled Reaction Environments To Model And Enhance Biomass Utilization By Cellulolytic Bacteria, Hsin-Fen Li

Theses and Dissertations--Chemical and Materials Engineering

Cellulose from energy crops or agriculture residues can be utilized as a sustainable energy resource to produce biofuels such as ethanol. The process of converting cellulose into solvents and biofuels requires the saccharification of cellulose into soluble, fermentable sugars. However, challenges to cellulosic biofuel production include increasing the activity of cellulose-degrading enzymes (cellulases) and increasing solvent (ethanol) yield while minimizing the co-production of organic acids. This work applies novel surface analysis techniques and fermentation reactor perturbations to quantify, manipulate, and model enzymatic and metabolic processes critical to the efficient production of cellulosic biofuels.

Surface analysis techniques utilizing cellulose thin film …

Membrane Immobilized Reactive Fe/Pd Nanoparticles: Modeling And Tce Degradation Results, Ruo He

Theses and Dissertations--Chemical and Materials Engineering

Detoxification of chlorinated organic compound is an important and urgent issue in water remediation nowadays. Trichloroethylene (TCE), as a model compound in this study, has been proved to be degraded effectively by bimetallic nanoparticles (NPs) in solution phase. In this study, Fe/Pd bimetallic NPs were synthesized in poly (acrylic acid) (PAA) functionalized polyvinylidene fluoride (PVDF) microfiltration membranes. TCE dechlorination with these bimetallic NPs was conducted under different pH values and different metal loadings to study the role of corrosion on reaction rates.

One-dimensional mathematical model with pseudo first-order reaction kinetic was introduced to discuss the TCE dechlorination profile in membrane …

Finite Element Analysis Of The Contact Deformation Of Piezoelectric Materials, Ming Liu

Theses and Dissertations--Chemical and Materials Engineering

Piezoelectric materials in the forms of both bulk and thin-film have been widely used as actuators and sensors due to their electromechanical coupling. The characterization of piezoelectric materials plays an important role in determining device performance and reliability. Instrumented indentation is a promising method for probing mechanical as well as electrical properties of piezoelectric materials.

The use of instrumented indentation to characterize the properties of piezoelectric materials requires analytical relations. Finite element methods are used to analyze the indentation of piezoelectric materials under different mechanical and electrical boundary conditions.

For indentation of a piezoelectric half space, a three-dimensional finite element …

Study Of Characterization Of Submicron Coal Particles Dispersed In Air And Capture Of Coal Particles By Water Drops In A Scrubbing Column, Utshab Chakravorty

Theses and Dissertations--Chemical and Materials Engineering

Present day water spray based dust removal technologies do not effectively remove respirable submicron coal and silica dust particles in the underground coal mines causing Coal worker’s pneumoconiosis (CWP). The objective of this research was to study the electrostatic charges present in the airborne coal dust in order to develop efficient water spraying based dust removal technology where water drops charged using ionic compounds and surfactants would be used to capture the oppositely charged coal particles. In an experimental scrubbing column, coal particles dispersed in an air stream by a Fluidized Bed Aerosol Generator were captured by water drops sprayed …

Synthesis And Characterization Of Functionalized Naphthalenes And Anthracenes, Guang Zhang

Theses and Dissertations--Chemistry

Organic electronics have received significant development in the last few decades. p- Type materials are much more in availability than n-type now. There are only a few examples of air-stable n-type materials. The design and synthesis of novel air-stable ntype materials is still a focus of research. Herein is described a study to evaluate the effectiveness of a novel electron-withdrawing group, composed of three electronwithdrawing groups connected in series, to impart material properties known to be favorable for obtaining air-stable n-types. The smaller acenes, naphthalene and anthracene, carrying these electron-withdrawing groups were prepared and studied by UV-Vis absorption spectroscopy and …

Novel Aromatic Ion–Pairs: Synergy Between Electrostatics And Π-Face Aromatic Interactions, Pramod Prasad Poudel

Theses and Dissertations--Chemistry

This dissertation focuses on the design and study of charged aromatic molecules where weak π-π interactions synergize with electrostatic interactions to enhance the overall interaction between aromatic moieties. Each chapter investigates some aspect of this hypothetical synergy between electrostatics and π-face aromatic cohesion.

The first chapter unveiled the importance of electrostatics in the intramolecular stacking of flexible aromatic molecular templates 1-2Br and 2a. While our previous studies found dicationic molecular template 1-2Br to have intramolecular π-stacking between electron poor pyridinium and electron rich xylylene moieties, no such stacking interaction was observed in the neutral analog 2a.

Chapter two systematically …

Investigation Of The Critical Residues At The C-Terminus Of The E.Coli Periplasmic Chaperone, Sura, Brent Ferrell

Theses and Dissertations--Chemistry

SurA is a molecular chaperone in the periplasm of E.coli and has been implicated in the maturation of outer membrane proteins (OMPs). SurA consists of four domains, but only two of them, namely the N and C-­terminal domains, are necessary for chaperone function. Very little is known about which residues drive the interaction between the N and C-­termini that facilitates normal activity. We mutated several conserved residues on the C-terminus and generated additive truncations to observe the effects of each on the fitness of the cell. We found one mutation E(408):A was sufficient to reduce SurA activity by 3-­fold, but …

Development Of Novel Chemical Tools For Proteasome Biology & A New Approach To 1-Azaspirocyclic Ring System, Lalit Kumar

Theses and Dissertations--Chemistry

The proteasome, a multiprotease complex, is clinically validated as an anticancer target by the FDA approval of bortezomib and carfilzomib for the treatment of multiple myeloma. The emergence of resistance to proteasome inhibitors however remains a major clinical challenge. Recently, distinct types of proteasomes termed ‘intermediate proteasomes’, which contain unconventional mixtures of catalytic subunits, have been implicated with drug resistance of tumor cells. In elucidating the role of intermediate proteasomes in drug resistance, a crucial step is to unequivocally determine the subunit composition of intermediate proteasomes in cells. With this in mind, the goal of the studies reported in this …

Purpose As Content And Pedagogy: Rationale-Development As A Core Theme Of Social Studies Teacher Education, Todd Stevenson Hawley

Journal of Inquiry and Action in Education

Grounded in a belief in the transformative possibilities of social studies teacher education, I present an argument for considering the development of purpose as both content and pedagogy of social studies teacher education. As part of developing a coherent pedagogy of rationale-based social studies teacher education, I begin by exploring the influence of competing conceptions regarding the purpose of social studies teaching and learning on the work of social studies teacher educators. Next, I consider three distinct paths social studies teacher educators have taken to prepare teacher candidates for content and pedagogical decision-making as first-year teachers. While each has potential, …

The Effects Of Clinical Experiences On The Understanding Of Classroom Management Techniques, Carey Anne Cushmann, Andrew T. Kemp

Journal of Inquiry and Action in Education

For teacher educators, classroom management education is one of the least researched aspects of the profession. The purpose of this study was to determine if classroom management was most effective learned through textbook analysis coupled with classroom discussion, or the experience of observing and practicing classroom management in the clinical experience. The results of this study suggest that the clinical experience is the major contributor to feelings of confidence in classroom management situations. There is a significant difference in confidence between the classroom understanding and the post-clinical experience in regards to general classroom management understandings and confidence.

Leptin Promotes Glioblastoma , Johnathan Lawrence, Nicholas J. Cook, Richard A. Rovin, Robert J. Winn

Journal Articles

The hormone leptin has a variety of functions. Originally known for its role in satiety and weight loss, leptin more recently has been shown to augment tumor growth in a variety of cancers. Within gliomas, there is a correlation between tumor grade and tumor expression of leptin and its receptor. This suggests that autocrine signaling within the tumor microenvironment may promote the growth of high-grade gliomas. Leptin does this through stimulation of cellular pathways that are also advantageous for tumor growth and recurrence: antiapoptosis, proliferation, angiogenesis, and migration. Conversely, a loss of leptin expression attenuates tumor growth. In animal models …

The Freshwater Crabs Of Ethiopia, Northeastern Africa, With The Description Of A New Potamonautes Cave Species , Neil Cumberlidge, Paul F. Clark

Journal Articles

No abstract provided.

Nonconscious Attention Bias To Threat Is Correlated With Anterior Cingulate Cortex Gray Matter Volume: A Voxel-Based Morphometry Result And Replication, Joshua M. Carlson, Felix Beacher, Karen S. Reinke, Reza Habib, Eddie Harmon-Jones, Lilianne R. Mujica-Parodi, Greg Hajcak

Journal Articles

No abstract provided.

Course Schedule Spring 2012, William & Mary Law School

Course Information

No abstract provided.

Spectroscopic Detection And Characterization Of Jet-Cooled Transient Molecules, Mohammed Gharaibeh

Theses and Dissertations--Chemistry

Transient molecules are of great importance due to their critical role as intermediates in the semiconductor industry, in upper atmosphere reactions, and in astrochemistry. In the present work, reactive intermediates were produced in the laboratory by applying an electric discharge through a suitable precursor gas mixture and studied by means of their laser-induced fluorescence and emission spectra.

The band systems of and have been studied in detail. The energy levels of both isotopologues were fitted with a Renner-Teller model, and the isotope relations have been used to test the validity of the derived parameters.

The A²Π_u - …

You Kill Me: Why I Don’T Want To Live Around People With Guns, Brandt Goldstein

Other Publications

No abstract provided.

Ilr Masthead Volume 35

ILR Past Mastheads

No abstract provided.

Variability And Trends Of Aerosol Properties Over Kanpur, Northern India Using Aeronet Data (2001–10), Dimitris G. Kaskaoutis, Ramesh P. Singh, Ritesh Gautam, Manish Sharma, P. G. Kosmopoulos, S. N. Tripathi

Mathematics, Physics, and Computer Science Faculty Articles and Research

Natural and anthropogenic aerosols over northern India play an important role in influencing the regional radiation budget, causing climate implications to the overall hydrological cycle of South Asia. In the context of regional climate change and air quality, we discuss aerosol loading variability and trends at Kanpur AERONET station located in the central part of the Indo-Gangetic plains (IGP), during the last decade (2001-10). Ground-based radiometric measurements show an overall increase in column-integrated aerosol optical depth (AOD) on a yearly basis. This upward trend is mainly due to a sustained increase in the seasonal/monthly averaged AOD during the winter (Dec-Feb) …

A Mentality Study On Drawings Of Flood Victims, Lertsiri Bovornkitti

Asian Medical Journal and Alternative Medicine

Massive flooding in parts of Thailand during the period September - November 2011 had great impacts on residents of the areas affected. The Faculty of Fine Arts, Srinakharinwirot University, set up one of the relief teams. As a faculty staff member, the author undertook a visual art project among those affected.

The study was carried out on 74 immigrants at the Rajamangala Stadium Shelter; the drawings at the site were examined for their mentality status. The fi ndings disclosed 21 of the 74 subjects expressed aspects of the disaster event in their drawings, among which 12 subjects expressed some mental …

Comparison Of Physical Fitness Levels Among Girls In Child Welfare And School Children Aged 7-9 Years, Wanwisa Sudsatiantanon, Suthep Srimuengkaew, Tatcha Paktapa, Kedsara Rakpongsiri

Asian Medical Journal and Alternative Medicine

Children with a good physical fi tness affect to their ability to perform physical activities and well-being of children in the future. Previous studies found that environmental and lifestyle patterns have different effects on physical fi tness.This study to compare physical fitness among girls in child welfare and school children aged 7-9 years. Participants were 47 females of child welfare and 42 females of school children. Participants in this study receive a questionnaire, body mass index measurement and physical fi tness test. It found that sit & reach and standing broad jump test in school children were lower than child …

Study On The Safety Of Thunbergia Laurifolia Lindl. Extract Capsule By Oral Administration On Healthy Volunteers Phase I, Onchada Sittiprom, Kumpol Amnauypattanapon, Junya Pattaraarchachai, Arunporn Itharat, Somboon Kietinun

Asian Medical Journal and Alternative Medicine

The purposes of this clinical trial phase I were to study the safety and side effects of Thunbergia laurifolia Lindl. water extract at dose 600 milligram per day, calculated by probabilistic multiplication method to be a Reference Dose (RfD), on 10 healthy volunteers, which was permitted by ethical review committee Faculty of Medicine, Thammasat University. Five males and 5 females’ healthy volunteers, age between 20-29 years old, received 600 milligram water extract of Thunbergia laurifolia Lindl. orally per day in the morning for 14 days and washout period for 14 days. The CRF and TMSE were performed and analyzed using …

Treatment Of Trigeminal Neuralgia With Microvascular Decompression, Pree Nimmannitya

Asian Medical Journal and Alternative Medicine

Trigeminal neuralgia has been discovered for a very long time. In the past, medical technology and medical knowledge could not explain pathophysiology of these symptoms. The treatment has been the trials and errors for a long time until carbamazepine was discovered, which is nowaday still the first line drug for treatment and also the therapeutic diagnosis for trigeminal neuralgia. However carbamazepine's tolerance and side effect are still major problems. Patient diagnosed with trigeminal neuralgia has to suffer with their facial pain and their daily life, because the patient’s activity, such as talking, chewing, can cause a severe pain. This literature …

Present Knowledge In Nutrition For The Elderly, Nusiri Lerdvuthisopon

Asian Medical Journal and Alternative Medicine

Good nutrition determines the quality of life throughout life span. Adequate and balance energy and nutrients intake is the principle of good nutrition in the age. The aim of the review is also to verify and update the knowledge of nutrition in elderly in order to give the essential message that appropriate for the real practice in geriatrics. It pins point on how nutrition can prevent non-communicable chronic diseases, help to sustain biochemical homeostasis, ameliorate the chronic low-grade infl ammation, improve immunity and support the sex hormones imbalance during senescence.