Digital Commons Network^™

Dissociating Allopregnanolone Mnemonic Effects From Sedation, Sarah B. Hartman

Honors Projects

Allopregnanolone (Allop) is a neurosteroid metabolite of progesterone. Allop modulates cognition, specifically learning and memory, but these effects are frequently confounded by its anxiolytic and sedative properties. We attempted to dissociate the anxiolytic effects of Allop from its mnemonic effects by employing a pharmacological challenge with d- amphetamine. Because previous research suggests that the effects of Allop may vary with the cognitive domain being tested, we assessed both spatial and non-spatial memory. Spatial memory was tested in a Morris Water Maze, and non-spatial object memory was tested on a novel discrimination task. Allop, alone or in combination with d-amphetamine …

Medical School Watercooler Newsletter - April 22, 2012, Lindsey Lyle

Watercooler Newsletter

This is the April 22, 2012 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents Include:

• USA Student Health Center Achieves AAAHC Accreditation
• Dr. Parker Awarded 2012 Bruno Lima Award
• Dr. Dan Roach Appointed State Health Information Technology Coordinator
• USA Physician Featured on Fox 10 TV
• Snapshots: Medical Center Employee Picnic
• Next Week's DSS - Dr. Yidong Bai

2011-2012 Lindenwood University Honors Convocation, Lindenwood University

Honors Convocation Programs

2011-2012 Lindenwood University Honors Convocation

High Dispersal Ability Inhibits Speciation In A Continental Radiation Of Passerine Birds, Santiago Claramunt, Elizabeth P. Derryberry, Jr V. Remsen, Robb T. Brumfield

Faculty Publications

Dispersal can stimulate speciation byfacilitating geographical expansion across barriers or inhibit speciation by maintaining gene flow among populations. Therefore, the relationship between dispersal ability and speciation rates can be positive or negative. Furthermore, an 'intermediate dispersal' model that combines positive and negative effects predicts a unimodal relationship between dispersal and diversification. Because both dispersal ability and speciation rates are difficult to quantify, empirical evidence for the relationship between dispersal and diversification remains scarce. Using a surrogate for flight performance and a species-level DNA-based phylogeny of a large South American bird radiation (the Furnariidae), we found that lineages with higher dispersal …

Investigation Of The Calcification Response Of Foraminifera And Pteropods To High Co2 Environments In The Pleistocene, Paleogene And Cretaceous, M Hart, L Pettit, D Wall-Palmer, J Hall-Spencer, C Smart, A Medina-Sanchez, Rm Prol-Ledesma, R Rodolfo-Metalpa, P Collins

School of Biological and Marine Sciences

No abstract provided.

Hierarchical Multi-Label Classification: Going Beyond Generalization Trees, Peerapon Vateekul

Open Access Dissertations

Traditional approach to automated classification assumes that each object should be assigned to only one out of two or more classes. However, some real-world applications digress from this generic scenario in two important ways. First, each example can belong to several classes simultaneously (multi-label classification). Second, the classes can be hierarchically ordered in the sense that some are more specific versions of others (hierarchical classification). Seeking to address both of these issues, the presented work deals with “hierarchical multi-label classification”. In non-hierarchical multi-label classification, literature survey indicates that good performance is achieved when a Support Vector Machine (SVM) is used …

2012 Undergraduate Research Symposium Abstract Book, Academic Center For Enrichment

Undergraduate Research Symposium Abstract Books

Abstract book from the 2012 Twelfth Annual UMM Undergraduate Research Symposium (URS) which celebrates student scholarly achievement and creative activities.

Sbe Notícias, Ano 7, No. 224, April 21, 2012, Marcelo A. Rasteiro, Delci K. Ishida, Agatha Matsumoto

SBE Notícias

Visão, Missão e Valores Institucionais da SBE; GUPE lança novo vídeo; Homenagem aos 80 anos de Pierre Alphonse Albert Martin; Artigos sobre carste na Revista Brasileira de Geociências; Novo mineral é descoberto em gruta espanhola; Mini-tissunami subterrâneo; O maior inseto subterrâneo terrestre da Europa; Bactéria resistente à antibióticos é descoberta em caverna americana; 1º Campeonato de Canionismo da Comunidade de Valencia; Bondinho de Ubajara está parado há mais de 20 dias; 21ª Conferência Internacional de Biologia Subterrânea; Foto do Leitor: Portal do Vale Encantado (TO)

A Plant Virus Substrate Induces Early Upregulation Of Bmp2 For Rapid Bone Formation, Pongkwan Sitasuwan, L. Andrew Lee, Peng Bo, Erin N. Davis, Yuan Lin, Qian Wang

Faculty Publications

Many nanoscale materials have been developed to investigate the effects on stem cell differentiations via topographical and chemical cues for applications in tissue engineering and regenerative medicine. The use of plant viruses as cell supporting substrates has been of particular interest due to the rapid induction of bone marrow derived mesenchymal stem cells (BMSCs) towards osteogenic cells. In this study, the role of Tobacco mosaic virus (TMV) and its early effects on osteoinduction with particular emphasis on the regulation of bone morphogenetic protein-2 (BMP2) was examined. We observed that the cells on the virus substrate immediately aggregated and formed bone-like …

Toxicity Of Tio₂ Nanoparticles In The Genomic Dna Of Cucurbita Pepo, Fabiola Moreno-Olivas^, Vincent Gant, Isaac Montes, Hiram Castillo-Michel, Kyle L. Johnson, Jose R. Peralta-Videa, Jorge L. Gardea-Torresdey*

COURI Symposium Abstracts, Spring 2012

The nanomaterial industry is growing very fast and nanoparticles (NPs) are used in variety of instruments and goods. NPs can reach the plants through different manners; though, little is known about their impact on food crops and the possible effects in the food chain are unknown. In this research, the possible genotoxic effects of TiO₂ NPs on zucchinis (Cucurbita pepo) were studied. Seven-day old hydroponically grown zuchinnis plants were treated for 7 days with TiO₂ NPs suspended in the nutrient solution at concentrations varying from 0 to 50 mg/L. Random amplified polymorphic DNA assay was performed and showed the …

Herbaceous 2012 (April 21), Amy L. Myers, Julia I. Chapman, Ryan W. Mcewan

Data Files: Drew Woods Permanent Plots

Herbaceous vegetation data collected in 2012 at Drew Woods State Nature Preserve in Darke County, OH. Data key is provided in a supplemental file.

Spokane Intercollegiate Research Conference 2012, Gonzaga University

SIRC Event Programs

No abstract provided.

Preparation Of Ferrite Layers By Electrophoretic Deposition / Hee Ay Ching, Ay Ching Hee

Student Works (2010-2019)

Nickel zinc ferrite and magnesium copper zinc ferrite powders with average particle size about 22.7 nm and 26.6 nm respectively were synthesized by water-in-oil microemulsion technique. The coercivity values for magnesium copper zinc ferrite and nickel zinc ferrite were 126 Oe and 25.5 Oe respectively which indicates soft ferromagnetic behaviour. A colloidal suspension of the fine ferrite powder in ethanol was prepared. Phosphate Ester (PE) was added to the suspension as charging agent, Poly Vinyl Butyral-co-vinyl-alcohol-co-vinyl acetate (PVB) as binder and Poly Ethylene Imine (PEI) as dispersant. The effect of the charging agent on the stability of the ferrite suspension …

Activity Choice And Extinction Intervention For Escape Maintained Behavior, Ali M. Markowitz

Honors Theses

Tantrums and non-compliant problem behaviors challenge children diagnosed with autism’s progress in early childhood special education classrooms by interfering with the child’s learning opportunities. Autism is a pervasive developmental disorder causing abnormal or impaired development in social interactions and communication (DSM-IV, 1994). This paper looks at a single case on a preschool aged child diagnosed with autism exhibiting tantrums and problem behaviors. These tantrums and non-compliant problem behaviors included kicking, scratching, screaming, hitting, flopping on to the floor or eloping (leaving the table, chair or work area). One study conducted showed that activity choice intervention decreases the occurrence of problem …

Morphological Variation And Trophic Partitioning Among Central Mexican Lake Silversides, Daniel Powell

Academic Summit

Central Mexican Lakes Silversides species (i.e. Chirostoma) show limited genetic variation for individuals with significant levels of morphological variation. Trophic partitioning is believed to influence the elevated diversity in the region but is not well understood. This study examined the association between diet and morphology, focusing on internal digestive anatomy and head shape. Dissections were performed to determine relative intestine length as related to trophic position. No clear relationship was determined. Head shape was analyzed using geometric morphometric analysis to help quantify replicated patterns of divergence between lakes. Results largely support independent divergence along the same axes in mophospace.

The Evaluation Of Novel Beta-Lactam Antibiotics On Clinical Bacterial Isolates, Melvin Grimes

Academic Summit

The distribution and occurrence of multi-drug resistant bacteria is an increasing public health problem. The emergence of resistant bacteria makes the task of synthesizing new antibiotics imperative to combating these bacteria. In this study, new beta-lactam antibiotics are tested for broad spectrum activity using clinical E. coli and Staphylococcus aureus strains. The clinical isolates were grown on Mueller Hinton (MH) agar. The novel beta-lactam antibiotics were placed on sterile disc and placed on the MH plates, incubated overnight, and each zone of inhibition was measured. Our results show several novel antibiotics are effective against the clinical isolates.

New Antioxidant Prenylated Benzophenone Derivative From Native Louisiana Species Of Hypericum Hypericoides, Shreedu Pradhan

Academic Summit

Oxidation plays a critical role in cell senescence and the progression of disorders like cancer and cardiovascular disease. Antioxidants are known to modulate several of these disease pathways. In our survey of plants native to Louisiana, a new prenylated benzophenone derivative was isolated from the ethyl acetate extract of the aerial parts of Hypericum hypericoides. Inspection of other plant parts yielded the known metabolites, 7-epiclusianone and clusianone. The structure and stereochemistry of the metabolites were determined by spectroscopic methods. The new derivative displayed antioxidant activity at a concentration of 1 mg/mL in the 3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazolium bromide colorimetric assay.

Is Erod Activity Affected By The Molting Cycle In The Fiddler Crab, Uca Pugilator?, Kate Hotard

Academic Summit

If crustacean ethoxyresorufin O-deethylase (EROD) activity varies with the molting physiology, then the use of random crustacean EROD activity and whole tissue samples as biomarkers for pollution can be questioned. This study determined if mitochondrial or microsomal EROD activities in the hepatopancreas were affected by the molting physiology in the fiddler crab, Uca pugilator. Intermolt crabs were injected with the exogenous molting hormone 20-hydroxyecdsyone. Results showed a significant increase in mitochondrial EROD activity suggesting that mitochondrial EROD activity is influenced by molting physiology. Only microsomal cell fractions should be used to perform crustacean EROD assays when evaluating aquatic pollution.

Initial Trends In The Kentucky Buck Test Program, Robert S. Kelly

Morehead State Theses and Dissertations

A thesis presented to the faculty of the College of Science and Technology at Morehead State University in partial fulfillment of the requirements for the Degree of Master of Science by Robert S. Kelly on April 20, 2012.

Impact Of Accelerometry And Spirography Data Analysis Of Essential Tremor On Bold-Fmri Data Interpretation, Saman Sargolzaei

Open Access Theses

Essential Tremor (ET) is the most common neurological movement disorder, with slowly progressive symptoms that impact the patient's quality of life and ability to perform activities of daily living. Tremors in ET occur during kinetic, with two subtypes: postural tremors and kinetic tremors. Postural tremors appear when the arms are topically maintained in a position against gravity, whereas kinetic tremors appear during sustained voluntary movements such as writing or drawing. The underlying mechanisms of either tremor type are not known, and further work is needed to determine whether they are two manifestations of the same brain dysfunction, or consequences of …

Modulation Of Gain-Of-Function α6*-Nicotinic Acetylcholine Receptor By β3 Subunits, Bhagirathi Dash, Ronald J. Lukas

Translational Neuroscience

We previously have shown that β3 subunits either eliminate (e.g. for all-human (h) or all-mouse (m)α6β4β3-nAChR) or potentiate (e.g. for hybrid mα6hβ4hβ3- or mα6mβ4hβ3- nAChR containing subunits from different species) function of α6*-nAChR expressed in Xenopus oocytes, and that nAChR hα6 subunit residues Asn-143 and Met-145 in N-terminal domain loop E are important for dominant-negative effects of nAChR hβ3 subunits on hα6*-nAChR function. Here, we tested the hypothesis that these effects of β3 subunits would be preserved even if nAChR α6 subunits harbored gain-of-function, leucine- or valine-to-serine mutations at 9′ or 13′ positions (L9′S or V13′S) in their second transmembrane …

Socialization With Alcohol Or Alcohol As Socialization: An Actor-Network Theory Approach To Understanding College Student Alcohol Use, Sean B. Hoops

Sociology Honors Projects

Many studies of college student drinking focus on understanding the problematic consequences of alcohol use. This research, however, does less to illuminate the cultural meanings of the use of alcohol. To address this gap, I examine how students relate to drinking alcohol socially, paying particular attention to how drinking and non-drinking emerge as meaningful behaviors in particular social settings. I analyze drinking qualitatively, focusing on the student perception of the significance of alcohol consumption as part of social interaction to understand the impact that alcohol itself has on the social setting. By employing an Actor-Network Theory framework I conclude that …

Energetic Plasticity Underlies A Variable Response To Ocean Acidification In The Pteropod, Limacina Helicina Antarctica, Brad A. Seibel, Amy E. Maas, Heidi M. Dierssen

Biological Sciences Faculty Publications

Ocean acidification, caused by elevated seawater carbon dioxide levels, may have a deleterious impact on energetic processes in animals. Here we show that high PCO₂ can suppress metabolism, measured as oxygen consumption, in the pteropod, L. helicina forma antarctica, by ~20%. The rates measured at 180–380 µatm (MO₂ = 1.25 M^−0.25, p = 0.007) were significantly higher (ANCOVA, p = 0.004) than those measured at elevated target CO₂ levels in 2007 (789–1000 µatm, = 0.78 M^−0.32, p = 0.0008; Fig. 1). However, we further demonstrate metabolic plasticity in response to regional …

2012 Uab Expo, University Of Alabama At Birmingham

Expo Programs

Catalog of undergrauate student research poster presentations with abstracts.

The Communicator, April 20, 2012, Bronx Community College

The Communicator

The Communicator newspaper published on April 20, 2012.

Traversing Swanton Road, 7th Ed., James A. West

Academic, Government & Associated Organizational Research Resources

Situated at the northwest end of Santa Cruz County and occupying circa 30 square miles of sharply contrasted terrain, the Scott Creek Watershed concentrates within its geomorphological boundaries, at least 10-12% of California's flora, both native and introduced. Paradoxically, the use/abuse that the watershed has sustained over the past 140+ years, has not necessarily diminished the biodiversity and perhaps parallels the naturally disruptive but biologically energizing processes (fire, flooding, landslides and erosion), which have also been historically documented for the area for +60 years. This is an early edition of an extensive document by James A. West. Please visit the …

April 20, 2012, Ohio University Board Of Trustees Meeting Minutes, Ohio University Board Of Trustees

Board of Trustees Meeting Minutes

Meeting minutes document the activities of Ohio University's Board of Trustees.

Elementary/Special Education Lesson Plan Description Lesson Plan Format, Kristen Gavinelli

Petersheim Academic Exposition

No abstract provided.

The Utah Statesman, April 20, 2012, Utah State University

The Utah Statesman

Weekly student newspaper of Utah State University in Logan.

No Girls In The Clubhouse: A Historical Examination Of The Institutional Exclusion Of Women From Baseball, Rebecca A. Gularte

Scripps Senior Theses

An examination of the origins of the separation of boys into baseball and girls into softball due to Victorian era ideas about gender, and the current day institutional exclusion through Title IX and culturally constructed notions about the appropriate place of women in the sporting world.