Digital Commons Network^™

What Can Go Wrong With Dna Profiling, Dan E. Krane

Biological Sciences Faculty Publications

No abstract provided.

Observer Effects In Dna Profiling, Dan E. Krane

Biological Sciences Faculty Publications

No abstract provided.

Statistical Weights Of Mixed Dna Profiles, Dan E. Krane

Biological Sciences Faculty Publications

Presentation recording from December 2012 can be found at http://youtu.be/daRBTopFA1A.

Part of the Forensic DNA Profiling Video Series.

Implications Of Database Searches For Dna Profiling Statistics, Dan E. Krane

Biological Sciences Faculty Publications

No abstract provided.

The Sunflower Forest: An Educator’S Resource Guide, Kathy Everts Danielson

Teacher Education Faculty Publications

Loren Eiseley (1907-1977) was an acclaimed writer who grew up in and around Lincoln, Nebraska. An anthropologist by training and vocation, he wrote more than a dozen books of essays and poetry, most focused on the mysteries of nature and humankind's relationship to the natural world.

The "Sunflower Forest" is a theme that appears in Eiseley's book The Invisible Pyramid (1970). As a child, Eiseley enjoyed playing in the large stands of sunflowers that sprang up every year on a floodplain near his home in Lincoln. He would later think of the "sunflower forest" as a place for connecting with …

Situation Analysis Of Somalia’S 2011 Famine, Ahmed Mohamed Askar

Master of Public Health Program Student Publications

This CE examined the contributing factors of famine in Somalia and developed a situation analysis of Somalia’s 2011 famine. The situational analysis was developed using health and famine indicators. Data from geographic information system (GIS) was also used to supplement analysis to look for trends and patterns of the famine. I predicted that conflict was the leading factor in Somalia’s 2011 famine. I concluded that conflict exacerbated the famine situation in the south of Somalia but in the north (Somaliland) famine was due to climate and lack of permanent rivers and water sources.

Metabotropic Glutamate Receptor 5 In The Medial Prefrontal Cortex: Role In Cocaine Sensitization And Addiction, Kristin Marie Timmer

Theses and Dissertations (ETD)

Cocaine sensitization is associated with cocaine-induced hyperexcitability of pyramidal projection neurons within the medial prefrontal cortex (mPFC). Such hyperexcitability presumably results in increased glutamatergic input to reward-affiliated brain regions such as the ventral tegemental area (VTA) and nucleus accumbens (NAc), consequently facilitating drugseeking behavior. Metabotropic glutamate receptor 5 (mGluR5) has been implicated in cocaine addiction and demonstrated to increase neuronal excitability, therefore, the aim of the present study was to investigate the effect of intra-mPFC mGluR5 manipulation on behavioral and neurochemical sensitization and drug-seeking. Bilateral cannulae were implanted into the mPFC of male Sprague-Dawley rats and mGluR5 antagonist MTEP (15 …

The Impact Of Islam On Women In The Middle East A Discussion Of The Political Role Of Islam In Turkey, Saudi Arabia, And Lebanon, Elise Barimo

HIM 1990-2015

The social instability of the Middle East is often assumed to be consequential predominantly from the influences of extreme traditional Islamic practices; with substantial prominence placed upon the treatment of and violence against Middle Eastern women. This discussion seeks to directly prove the prevalence of Islamic influence on Middle Eastern politics and the resulting social instability. This assessment is designed around an interdisciplinary examination of coalescent factors. By assessing the political history, social and cultural lifestyle, and political and legal situation of the region, the assessment examines the contributors to the social instability of Saudi Arabia, Lebanon, and Turkey. The …

The Influence Of Beliefs On People's Perception Of Illness In The Spanish Golden Age, Nicole Cruz

HIM 1990-2015

Medicine is a field of science that is always changing and promoting new ideas and innovations. Throughout history, medicine has been an important factor in the lives of people around the world since the beginning of civilizations. This study focused on the literature of medicine as it relates to the Spanish Golden Age period. By looking at the history and critical studies in medicine during sixteenth and seventeenth century Spain as well as during the pre-colonial period in America, this thesis overviews the effects and influences in regards to health and illness in Spain and the Americas during the Spanish …

The Effects Of Adoption On Identity Formation A Qualitative Analysis, Lisa Heath

HIM 1990-2015

While evidence suggests that adoptees do not differ from non-adoptees in their ability to achieve a stable sense of identity, much is still unknown about how specifically the fact of being adopted affects one's identity. The purpose of this research is to take a deeper look at the significance and meaning of being adopted to one's sense of identity through qualitative analyses of in depth interviews with adoptees. Participants were recruited from Psychology classes via the SONA system. The participants (N = 16) took part in an in-depth structured interview and completed a survey battery which included a demographic questionnaire, …

Perceptions Of Preservice Teacher Candidates Towards Gifted Education Training And Obtaining The Gifted Education Endorsement Certificate In Florida, Zachary Laschober

HIM 1990-2015

According to the Institute for Research and Policy on Acceleration, training in gifted education is inaccessible by teacher candidates in colleges of education in the United States. This study involved the use of questionnaires with 100 teacher candidates enrolled on an introductory course on diversity in education in a Florida university. Teacher candidates responded to a series of items to identify beliefs about giftedness within and outside the context of education as well as the value of training in gifted education for educators. Of the 100 respondents, 79% agreed or strongly agreed with the need for specialized training for educators …

The Role Of Hsc-70 In Very Low Density Lipoprotein Tranport Vesicle Golgi Fusion Complex Formation, Erika Nafi Valencia

HIM 1990-2015

Excess production and secretion of very low-density lipoprotein (VLDL) by the liver into the circulatory system is directly related to atherosclerosis, a chronic cardiovascular disease that threatens the lives of many worldwide and continues to be a leading cause of death in the United States. The rate-limiting step in VLDL secretion is its transport from the site of biogenesis, the hepatic endoplasmic reticulum to the cis-Golgi. This step is mediated by a specialized ER- derived vesicle, the VLDL transport vesicle (VTV). Upon exit of the ER the VTV targets, fuses and delivers VLDL into the lumen of the Golgi. The …

Morphological Description Of Telaepolella Tubasferens N. G. N. Sp., Isolate Atcc©50593™, A Filose Amoeba In The Gracilipodida, Amoebozoa, Daniel J.G. Lahr, Gabriela M. Kubik, Anastasia L. Gant, Jessica Grant, O. Roger Anderson, Laura A. Katz

Biological Sciences: Faculty Publications

We describe the amoeboid isolate ATCC©50593™ as a new taxon, Telaepolella tubasferens n. g. n. sp. This multinucleated amoeba has filose pseudopods and is superficially similar to members of the vampyrellids (Rhizaria) such as Arachnula impatiens Cienkowski, 1876, which was the original identification upon deposition. However, previous multigene analyses place this taxon within the Gracilipodida Lahr and Katz 2011 in the Amoebozoa. Here, we document the morphology of this organism at multiple life history stages and provide data underlying the description as a new taxon. We demonstrate that T. tubasferens is distinct from Arachnula and other rhizarians (Theratromyxa, Leptophrys) in …

Engineered, Harnessed, And Hijacked: Synthetic Uses For Cytoskeletal Systems, Brian S. Goodman, Nathan D. Derr, Samara L. Reck-Peterson

Biological Sciences: Faculty Publications

Synthetic biology re-imagines existing biological systems by designing and constructing new biological parts, devices, and systems. In the arena of cytoskeleton-based transport, synthetic approaches are currently used in two broad ways. First, molecular motors are harnessed for non-physiological functions in cells. Second, transport systems are engineered in vitro to determine the biophysical rules that govern motility. These rules are then applied to synthetic nanotechnological systems. We review recent advances in both of these areas and conclude by discussing future directions in engineering the cytoskeleton and its motors for transport.

Colorimetric Oxygen Imaging And Quantification With Easily Accessible Optical Devices, Satya Achanta, Sanghan Park, Chang-Soo Kim

Electrical and Computer Engineering Faculty Research & Creative Works

Optical oxygen imaging is essential in monitoring two-dimensional analysis of oxygen distribution. Two easily accessible optical devices were used for oxygen analysis to demonstrate the feasibility of an innovatively simple method. a light panel screen with light-emitting diode (LED) backlight was used as a light source to excite a luminophore film responsive to oxygen. Meso-scale fluidic sensor platform was prepared using porphyrin complex (PtOEP) as the luminophore embedded within ethyl cellulose (EC) polymer matrix. Green LED light uniformly displayed from the light panel excited the luminophore film to exhibit two-dimensional luminescence distribution corresponding to wet gaseous oxygen. a color camera …

Cytoskeletal Strains In Modeled Optohydrodynamically Stressed Healthy And Diseased Biological Cells, Sean S. Kohles, Yu Liang, Asit K. Saha

Mechanical and Materials Engineering Faculty Publications and Presentations

Controlled external chemomechanical stimuli have been shown to influence cellular and tissue regeneration/degeneration, especially with regards to distinct disease sequelae or health maintenance. Recently, a unique three-dimensional stress state was mathematically derived to describe the experimental stresses applied to isolated living cells suspended in an optohydrodynamic trap (optical tweezers combined with microfluidics). These formulae were previously developed in two and three dimensions from the fundamental equations describing creeping flows past a suspended sphere. The objective of the current study is to determine the full-field cellular strain response due to the applied three-dimensional stress environment through a multiphysics computational simulation. In …

The Bellagio Global Dialogues On Intellectual Property, Joe Karaganis

Joint PIJIP/TLS Research Paper Series

This paper is an account of the Bellagio conferences and of their place within the larger arc of Rockefeller intellectual property work since 2002. In a more limited fashion, it is also an account of the transformation of IP from an obscure legal specialty into a major discourse of power and debate about the shape of globalization. The broadest achievement of the Bellagio series—and of Rockefeller Foundation work more generally in this area—has been to make this debate more open, participatory, and engaged with questions of poverty and human development.

Educational Concerns Of Implementing Biosand Water Filters In Rural Uganda, Matthew Engman Spowart

Dissertations, Masters Theses, Capstones, and Culminating Projects

The world is facing a shortage of clean drinking water. Current predictions, due to growing population, urbanization, and climate change estimate access to clean water to be further challenged in the coming years. Research has indicated that point of use (POU) technologies are likely to be the most efficient at delivering clean water (water cleaned of diarrhea causing microbes and bacteria) to rural populations. POU technologies, and specifically the biosand filter (BSF) are shown to be affordable, effective, and sustainable in rural areas. Many studies point to the need of proper education and follow-up with BSF users. BSF technology has …

Redundancy, Discrimination And Corruption In The Multibillion-Dollar Business Of College Admissions Testing, Monica Ellen Rizzo

Dissertations, Masters Theses, Capstones, and Culminating Projects

Most American colleges and universities require standardized entrance exams when making admissions decisions. Scores on these exams help determine if, when and where students will be allowed to pursue higher education. These scores are also used to determine eligibility for merit based financial aid. This testing persists even though half of the institutions that require the test scores from applicants have no idea if the scores offer any valuable information about prospective students. The purpose of this study is to examine the biases inherent in standardized college entrance exams, their validity as predictors of college completion, the actual value of …

Analysis Of Microsatellites From Sclerocactus Glaucus And Sclerocactus Parviflorus To Assess Hybridization Levels And Genetic Diversity, Anna Louise Schwabe

Master's Theses

Sclerocactus glaucus is an endemic Colorado species that is federally threatened under the Endangered Species Act. Sclerocactus glaucus is losing habitat due to disturbance by oil and gas exploration, urbanization, open range cattle grazing and recreational land use. Due to the low number of wild populations, conservationists question the genetic integrity of the species. Field biologists have observed S. glaucus populations with individuals possessing morphological characteristics of the closely related and widely distributed Sclerocactus parviflorus. Individuals from 28 populations of S. glaucus, 9 populations of S. parviflorus, and 1 population of S. cloveriae were sampled. Microsatellite analysis using 13 variable …

Pumilio Proteins Regulate Translation In Embryonic Stem Cells And Are Essential For Early Embryonic Development, Katherine Elizabeth Uyhazi

Yale Medicine Thesis Digital Library

Embryonic stem (ES) cells are defined by their dual abilities to self-renew and to differentiate into any cell type in the body. This vast potential is precisely controlled by spatial and temporal gene regulation at transcriptional, post-transcriptional, and epigenetic levels. Recent studies have revealed several transcription factors that are essential for stem cell self-renewal and pluripotency, but the role of translational control in ES cells is poorly understood. Translational control is a fundamental mechanism of gene regulation during early development, and likely explains the discrepancies between the transcriptome and proteome profiles of stem cells and their differentiated progeny. Pumilio proteins …

Friends Of The Library Mcnair Awards, The Mcnair Team

McNair Scholars Research Journal

No abstract provided.

Faculty Mentor Profile, The Mcnair Team

McNair Scholars Research Journal

No abstract provided.

Spatial Effect Of Reovirus Co-Infection On Production Of Rotavirus, Patricia Vignaux

McNair Scholars Research Journal

No abstract provided.

Life In Rural Ghana, Nidun Daniel

Verbum

In lieu of an abstract, below is the essay's first paragraph.

"I am a graduate of Saint John Fisher College (Class of 2011) with a double major in biology and religious studies. I recently took part in an international trip at my medical school in Old Westbury, NY. I attend the New York College of Osteopathic Medicine at NYIT. The collaboration between the NYIT Center for Global Health and the Jesse M. Rohde Foundation in Ghana helped create a trip that in itself was a life changing experience. Each and every day offered something new to our thoughts that paved …

Toxicity And Biological Effects Of Azo Dyes On Caenorhabdits Elegans, Dominique Sapp

Theses (Pre-2016)

Azote (AZO) dyes are a large class of synthetic organic dyes that contains in its structure an azo group, R-N=N-R', and make up most of the commercial dyes used in clothes and some in food. Some of these dyes have been found to cause carcinogenesis in different specimens. Caenorhabditis elegans is used to test the toxicity of several azo dyes at 50􁪽g/mL (50 ppm) and 20 ug/ml. (20 ppm) concentrations through bioassay. The brood size and life span are also determined placing the C. elegans onto Nematode Growth Media (NGM) agar that contains the concentrations of the highly toxic azo …

Tropisetron As A Neuroprotective Agent Against Glutamate-Induced Excitotoxicity: Potential Mechanisms Of Neuroprotection, Michael M. Swartz

Masters Theses

Glutamate-induced excitotoxicity has been shown to play a key role in a number of neurodegenerative diseases of the central nervous system. Activation of nicotinic acetylcholine receptors (nAChRs) significantly protects various types of neuronal tissues from excitotoxic cell death (Kaneko et al., 1997; Dajas-Bailador et al., 2000; Wehrwein et al., 2004; Thompson et al., 2006). Tropisetron is a highly selective 5-HT3 class serotonin receptor antagonist that is also a partial acetylcholine (ACh) agonist of the α7 nAChR (Papke et al., 2005). In the current study we aim to determine if tropisetron offers protection to adult pig RGCs. We further aim to …

Public Land Management Values: A Delphi Study Of Austrian And Pacific Northwest United States Recreation Resource Managers, Jessie Meybin

Graduate Theses, Dissertations, and Problem Reports (ETD)

There is a continuing global increase in recreational visitor use of public land. This rise in visitation can be a good thing if a proactive management plan utilizing strong methodology to anticipate impacts to an area and sustain its natural and social resources is in place. Although a wide spectrum of issues is presented to each management, few of the concepts are new to any of the administrators. With increasing duties, newly emerging concerns, and decreasing time, there is little room or patience for error concerning the implementation of any management derivatives or techniques. If the existing research on all …

Stream Restoration: Project Evaluation And Site Selection In The Cacapon River Watershed, West Virginia, Jonathan L. Pitchford

Graduate Theses, Dissertations, and Problem Reports (ETD)

Stream restoration is being conducted throughout the world at unprecedented rates to address stream channel degradation and water quality concerns. Natural Channel Design (NCD) is a common method used for restoration and has received governmental endorsement; however, the effects of NCD on channel stability and ecosystem functioning are poorly studied. We examined the effects of a reach-scale NCD project on channel stability, riparian vegetation, and water quality along the Cacapon River, West Virginia using a before-after-control-impact design and determined that restoration increased the abundance and diversity of woody vegetation, but had minimal effects on streambank stability and water quality. Increased …

Switchgrass Potential On Reclaimed Surface Mines For Biofuel Production In West Virginia, Michael A. Marra

Graduate Theses, Dissertations, and Problem Reports (ETD)

The high cost and environmental risks associated with non-renewable energy sources has caused an increased interest in, and development of renewable biofuels. Switchgrass (Panicum virgatum L.), a warm season perennial grass, has been investigated as a source of biofuel feedstock due to its high biomass production on marginal soils, its tolerance of harsh growing conditions, and its ability to provide habitat for wildlife and soil conservation cover. West Virginia contains vast expanses of reclaimed surface mine lands and could potentially benefit from the production of switchgrass as a biofuel feedstock. Furthermore, switchgrass production could satisfy Surface Mining Reclamation and Control …